Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain UBR4 23352 genome.wustl.edu 37 1 19481946 19481946 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020765.2 -1 validated p.E2097K 1.000 86 0% 67 46.3% 7 100% probably_damaging(0.971) tolerated(0.81) neutral(0.413) superfamily_ARM repeat MYOM3 127294 genome.wustl.edu 37 1 24411093 24411093 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_152372.3 -1 validated p.R612K 1.000 256 0% 161 62.1% 1 100% probably_damaging(1) tolerated(0.1) deleterious(0.786) HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III PPCS 79717 genome.wustl.edu 37 1 42925482 42925482 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024664.2 +1 validated p.S274L 1.000 168 0% 171 38.6% 10 70% possibly_damaging(0.926) tolerated(0.14) deleterious(0.624) HMMPfam_DFP,superfamily_DNA/pantothenate-metab_flavo_C PARS2 25973 genome.wustl.edu 37 1 55224179 55224179 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_152268.3 -1 validated p.A219V 0.973 49 0% 39 35.9% 10 70% possibly_damaging(0.827) deleterious(0) deleterious(0.758) HMMPfam_tRNA-synt_2b,superfamily_Class II aaRS and biotin synthetases DOCK7 85440 genome.wustl.edu 37 1 62995032 62995032 + Nonsense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000454575 -1 known p.S404* 1.000 205 0% 228 38.2% 5 60% benign(0) tolerated(1) - NULL LHX8 431707 genome.wustl.edu 37 1 75614349 75614349 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001001933.1 +1 validated p.L264 1.000 283 0% 325 36% 0 - - - - HMMPfam_Homeobox,HMMSmart_SM00389,superfamily_Homeodomain-like,PatternScan_HOMEOBOX_1 KCNC4 3749 genome.wustl.edu 37 1 110754258 110754258 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004978.3 +1 reviewed p.R46Q 1.000 50 0% 38 28.9% 3 66.6% probably_damaging(0.997) deleterious(0) deleterious(0.911) HMMSmart_SM00225,HMMPfam_K_tetra,superfamily_POZ domain PDE4DIP 9659 genome.wustl.edu 37 1 144994696 144994696 + Silent SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014644.4 -1 validated p.L12 1.000 270 0% 218 10.6% 2 0% - - - HMMPfam_Microtub_assoc BCL9 607 genome.wustl.edu 37 1 147084775 147084775 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004326.2 +1 reviewed p.Q49H 1.000 86 0% 96 40.6% 1 100% benign(0.139) tolerated(0.59) neutral(0.017) NULL BNIPL 149428 genome.wustl.edu 37 1 151010106 151010106 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_138278.3 +1 validated p.L35 1.000 417 0% 453 35.5% 0 - - - - NULL BNIPL 149428 genome.wustl.edu 37 1 151018277 151018277 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_138278.3 +1 validated p.R286W 0.997 129 0% 156 50.6% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00516,superfamily_CRAL/TRIO domain POGZ 23126 genome.wustl.edu 37 1 151380590 151380590 + Silent SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015100.2 -1 reviewed p.A787 1.000 223 0% 211 37.9% 25 60% - - - HMMSmart_SM00355 TCHH 7062 genome.wustl.edu 37 1 152085190 152085190 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007113.2 -1 provisional p.R168H 0.071 352 0% 290 36.9% 0 - unknown(0) - - NULL KCNN3 3782 genome.wustl.edu 37 1 154842430 154842430 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002249.4 -1 reviewed p.S4F 1.000 30 0% 12 33.3% 0 - unknown(0) deleterious(0) - NULL DPM3 54344 genome.wustl.edu 37 1 155112591 155112591 + Silent SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018973.3 -1 reviewed p.P72 0.996 27 0% 13 61.5% 328 32.6% - - - HMMPfam_DPM3 NOS1AP 9722 genome.wustl.edu 37 1 162313728 162313728 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014697.2 +1 reviewed p.G186E 0.906 136 0% 130 33.1% 12 41.6% possibly_damaging(0.698) tolerated(0.06) deleterious(0.574) NULL NOS1AP 9722 genome.wustl.edu 37 1 162324992 162324992 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014697.2 +1 reviewed p.G204A 0.985 82 0% 69 23.2% 10 60% benign(0.006) tolerated(0.53) neutral(0.007) NULL DARS2 55157 genome.wustl.edu 37 1 173808504 173808504 + Splice_Site SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018122.4 +1 reviewed e10-1 1.000 232 0% 228 33.3% 0 - - - - - CRB1 23418 genome.wustl.edu 37 1 197404606 197404606 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_201253.1 +1 reviewed p.G1205R 1.000 112 0% 86 23.3% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00179,HMMPfam_EGF,HMMSmart_SM00181,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_EGF/Laminin KIF21B 23046 genome.wustl.edu 37 1 200946397 200946397 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_017596.2 -1 provisional p.S1410L 0.003 100 0% 98 36.7% 14 21.4% benign(0.059) deleterious(0.01) neutral(0.410) HMMSmart_WD40,superfamily_WD40_like,HMMPfam_WD40 ELF3 1999 genome.wustl.edu 37 1 201982359 201982359 + Missense_Mutation SNP A A T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001114309.1 +1 validated p.K246N 0.863 117 0% 90 40% 950 46.7% probably_damaging(0.998) tolerated(0.4) deleterious(0.490) "superfamily_""Winged helix"" DNA-binding domain" SIPA1L2 57568 genome.wustl.edu 37 1 232649794 232649794 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020808.3 -1 validated p.S431L 0.998 124 0% 116 31% 3 0% benign(0.194) deleterious(0.02) neutral(0.401) NULL SLC35F3 148641 genome.wustl.edu 37 1 234452371 234452371 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_173508.2 +1 provisional p.I284 0.657 82 0% 60 46.7% 0 - - - - HMMPfam_DUF6,superfamily_SSF103481 COLEC11 78989 genome.wustl.edu 37 2 3660961 3660961 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024027.3 +1 validated p.T64M 0.938 46 0% 41 29.3% 0 - possibly_damaging(0.861) tolerated(0.06) deleterious(0.655) NULL FAM59B 150946 genome.wustl.edu 37 2 26399236 26399236 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000380681 +1 known p.E159K 1.000 45 0% 61 45.9% 6 33.3% probably_damaging(0.985) tolerated(0.17) deleterious(0.491) NULL C2orf16 84226 genome.wustl.edu 37 2 27804822 27804822 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032266.3 +1 validated p.E1795K 0.006 197 0% 181 34.8% 0 - benign(0.003) deleterious(0.02) neutral(0.383) NULL DHX57 90957 genome.wustl.edu 37 2 39085841 39085841 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_198963.1 -1 provisional p.E517K 1.000 224 0% 228 36.4% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) NULL MAP4K3 8491 genome.wustl.edu 37 2 39515382 39515382 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003618.2 -1 reviewed p.E452K 1.000 471 0% 442 33.7% 4 75% benign(0.042) tolerated(0.38) neutral(0.020) superfamily_Protein kinase-like (PK-like) AFTPH 54812 genome.wustl.edu 37 2 64794719 64794719 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_203437.2 +1 validated p.E653 1.000 172 0% 210 38.1% 3 66.6% - - - NULL PPP3R1 5534 genome.wustl.edu 37 2 68413769 68413769 + Missense_Mutation SNP T T C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000945.3 -1 validated p.Y99C 1.000 208 0% 281 35.2% 10 30% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00054,HMMPfam_efhand,superfamily_EF-hand ARHGAP25 9938 genome.wustl.edu 37 2 69049695 69049695 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000497259 +1 known p.Q334* 0.009 76 0% 78 33.3% 7 0% benign(0.086) tolerated(0.24) neutral(0.044) NULL PDCL3 79031 genome.wustl.edu 37 2 101186146 101186146 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024065.4 +1 validated p.E111K 0.826 217 0% 183 29% 9 44.4% benign(0.005) tolerated(0.77) neutral(0.001) HMMPfam_Phosducin,superfamily_Thiordxn-like_fd TUBA3E 112714 genome.wustl.edu 37 2 130953801 130953801 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_207312.2 -1 validated p.F49 1.000 315 0% 239 36.4% 0 - - - - HMMPfam_Tubulin,superfamily_Tubulin_FtsZ DPP4 1803 genome.wustl.edu 37 2 162862305 162862305 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001935.3 -1 reviewed p.E668K 1.000 272 0% 321 30.8% 0 - probably_damaging(1) deleterious(0.01) deleterious(0.905) HMMPfam_Peptidase_S9,superfamily_alpha/beta-Hydrolases SCN9A 6335 genome.wustl.edu 37 2 167168155 167168155 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002977.3 -1 reviewed p.E38K 0.994 237 0% 214 41.1% 0 - possibly_damaging(0.882) tolerated(0.28) neutral(0.376) NULL TTN 7273 genome.wustl.edu 37 2 179455115 179455115 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000356127 -1 known p.R17876H 1.000 265 0% 190 38.9% 0 - possibly_damaging(0.737) - - HMMPfam_fn3,HMMSmart_SM00060 UNC80 285175 genome.wustl.edu 37 2 210685159 210685159 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032504.1 +1 validated p.R696K 1.000 336 0% 294 33.7% 0 - benign(0.176) tolerated(0.53) neutral(0.024) NULL UNC80 285175 genome.wustl.edu 37 2 210840973 210840973 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032504.1 +1 validated p.I2840 1.000 213 0% 164 41.5% 0 - - - - NULL COL4A4 1286 genome.wustl.edu 37 2 227959001 227959001 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000092.4 -1 reviewed p.M403I 0.867 76 0% 70 38.6% 0 - benign(0.05) tolerated(0.33) neutral(0.027) HMMPfam_Collagen DNER 92737 genome.wustl.edu 37 2 230450669 230450669 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_139072.3 -1 validated p.S251F 1.000 159 0% 124 25.8% 0 - probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL NEU2 4759 genome.wustl.edu 37 2 233897502 233897502 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005383.2 +1 reviewed p.R41W 0.950 63 0% 54 46.3% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_Sialidase RBM44 375316 genome.wustl.edu 37 2 238726205 238726205 + Nonsense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001080504.2 +1 validated p.E216* 0.001 29 0% 41 26.8% 0 - - - - NULL PASK 23178 genome.wustl.edu 37 2 242072410 242072410 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015148.2 -1 validated p.V448I 0.000 112 0% 84 41.7% 20 45% benign(0) tolerated(0.29) neutral(0.029) NULL SETD5 55209 genome.wustl.edu 37 3 9483910 9483910 + Nonsense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001080517.1 +1 provisional p.S353* 1.000 256 0% 293 30% 40 40% - - - HMMPfam_SET,HMMSmart_SM00317,superfamily_SET domain ATP2B2 491 genome.wustl.edu 37 3 10379872 10379872 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001001331.2 -1 reviewed p.R1136 1.000 30 0% 32 53.1% 0 - - - - NULL PLCD1 5333 genome.wustl.edu 37 3 38052853 38052853 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001130964.1 -1 validated p.I235 0.996 46 0% 26 38.5% 10 50% - - - HMMPfam_efhand_like,superfamily_SSF47473 CXCR6 10663 genome.wustl.edu 37 3 45988223 45988223 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006564.1 +1 validated p.L84 0.949 317 0% 247 34% 10 0% - - - HMMPfam_7tm_1,superfamily_Family A G protein-coupled receptor-like RNF123 63891 genome.wustl.edu 37 3 49735317 49735317 + Splice_Site SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_022064.2 +1 reviewed e5-1 1.000 169 0% 143 34.3% 1 100% - - - - LRIG1 26018 genome.wustl.edu 37 3 66457841 66457841 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015541.2 -1 validated p.R337H 0.975 61 0% 41 36.6% 56 53.5% benign(0.027) tolerated(0.37) neutral(0.021) HMMPfam_LRR_1,HMMSmart_SM00369,HMMSmart_SM00365,superfamily_L domain-like ABI3BP 25890 genome.wustl.edu 37 3 100621498 100621498 + Missense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015429.3 -1 validated p.P105T 0.990 207 0% 255 27.1% 0 - probably_damaging(0.99) deleterious(0) deleterious(0.886) NULL TMPRSS7 344805 genome.wustl.edu 37 3 111799921 111799921 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001042575.2 +1 validated p.S715F 1.000 356 0% 373 30.3% 0 - probably_damaging(0.996) deleterious(0) deleterious(0.906) NULL SLC9A10 285335 genome.wustl.edu 37 3 112005587 112005587 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_183061.1 -1 validated p.V18L 0.426 151 0% 203 34% 0 - benign(0.219) tolerated(0.11) neutral(0.293) NULL KIAA2018 205717 genome.wustl.edu 37 3 113393719 113393719 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001009899.2 -1 validated p.E3Q 1.000 471 0% 580 37.4% 0 - probably_damaging(0.974) deleterious(0) deleterious(0.861) NULL ATP6V1A 523 genome.wustl.edu 37 3 113507614 113507614 + Silent SNP A A T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001690.2 +1 reviewed p.T257 0.637 264 0% 268 31.7% 27 40.7% - - - HMMPfam_ATP-synt_ab,superfamily_P-loop containing nucleoside triphosphate hydrolases IGSF11 152404 genome.wustl.edu 37 3 118647390 118647390 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001015887.1 -1 validated p.G130 1.000 171 0% 126 30.2% 9 55.5% - - - HMMSmart_SM00409,HMMPfam_V-set,superfamily_Immunoglobulin STXBP5L 9515 genome.wustl.edu 37 3 121097727 121097727 + Missense_Mutation SNP A A G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014980.2 +1 validated p.T805A 1.000 93 0% 118 40.7% 0 - benign(0.004) tolerated(0.77) neutral(0.001) NULL PIK3CA 5290 genome.wustl.edu 37 3 178952074 178952074 + Missense_Mutation SNP G G A rs121913283 TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006218.2 +1 reviewed p.M1043I 1.000 171 0% 152 36.8% 4 25% benign(0.256) deleterious(0.02) neutral(0.410) HMMSmart_PI3Kc,superfamily_Kinase_like TTC14 151613 genome.wustl.edu 37 3 180327803 180327803 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_133462.3 +1 validated p.D596N 1.000 94 0% 136 35.3% 0 - probably_damaging(1) tolerated(0.82) deleterious(0.500) NULL MCCC1 56922 genome.wustl.edu 37 3 182735089 182735089 + Missense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020166.3 -1 reviewed p.D672Y 1.000 214 0% 191 38.7% 25 44% probably_damaging(0.991) deleterious(0.02) deleterious(0.827) HMMPfam_Biotin_lipoyl,PatternScan_BIOTIN,superfamily_Hybrid_motif MUC4 4585 genome.wustl.edu 37 3 195512774 195512774 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018406.5 -1 reviewed p.D1893N 0.053 622 0% 455 19.3% 3477 26.9% possibly_damaging(0.748) - - NULL IDUA 3425 genome.wustl.edu 37 4 995294 995294 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000203.3 +1 reviewed p.E178K 1.000 74 0% 57 36.8% 105 23.8% probably_damaging(1) tolerated(0.11) deleterious(0.772) HMMPfam_Glyco_hydro_39,PatternScan_GLYCOSYL_HYDROL_F39,superfamily_Glyco_hydro_cat ATP8A1 10396 genome.wustl.edu 37 4 42583660 42583660 + Missense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006095.2 -1 reviewed p.G271V 1.000 180 0% 192 32.3% 1 0% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_E1-E2_ATPase,superfamily_Calcium ATPase transduction domain A CORIN 10699 genome.wustl.edu 37 4 47605589 47605589 + Silent SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006587.2 -1 reviewed p.I879 1.000 197 0% 190 38.9% 1 0% - - - HMMPfam_Trypsin,HMMSmart_SM00020,superfamily_Trypsin-like serine proteases FRYL 285527 genome.wustl.edu 37 4 48577226 48577226 + Missense_Mutation SNP A A C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015030.1 -1 validated p.F918L 1.000 145 0% 167 33.5% 1 0% benign(0.002) tolerated(0.7) neutral(0.002) superfamily_ARM repeat G3BP2 9908 genome.wustl.edu 37 4 76571551 76571551 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_012297.4 -1 validated p.E383K 1.000 188 0% 245 31.8% 4 25% possibly_damaging(0.456) deleterious(0.05) deleterious(0.495) HMMPfam_RRM_1,HMMSmart_SM00360,superfamily_RNA-binding domain RBD WDFY3 23001 genome.wustl.edu 37 4 85625503 85625503 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014991.4 -1 reviewed p.F2810L 1.000 204 0% 279 35.5% 8 62.5% possibly_damaging(0.92) deleterious(0.04) deleterious(0.720) HMMPfam_Beach,superfamily_BEACH domain C4orf3 401152 genome.wustl.edu 37 4 120225492 120225492 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000399075 -1 known p.H37Y 0.402 602 0% 622 30.7% 0 - benign(0.429) - - NULL FAT4 79633 genome.wustl.edu 37 4 126371928 126371928 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024582.4 +1 validated p.Q3253E 1.000 54 0% 58 29.3% 0 - probably_damaging(0.992) tolerated(1) neutral(0.448) HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like NAA15 80155 genome.wustl.edu 37 4 140263992 140263992 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_057175.3 +1 validated p.Q139* 1.000 190 0% 223 36.3% 2 0% - - - superfamily_TPR-like FGG 2266 genome.wustl.edu 37 4 155527950 155527950 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_021870.2 -1 reviewed p.D346H 1.000 318 0% 303 31.4% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Fibrinogen_C,HMMSmart_SM00186,superfamily_Fibrinogen C-terminal domain-like FGG 2266 genome.wustl.edu 37 4 155529686 155529686 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_021870.2 -1 reviewed p.L261 1.000 244 0% 206 33.5% 0 - - - - HMMPfam_Fibrinogen_C,HMMSmart_SM00186,superfamily_Fibrinogen C-terminal domain-like CLPTM1L 81037 genome.wustl.edu 37 5 1320770 1320770 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_030782.3 -1 provisional p.R498Q 1.000 54 0% 39 33.3% 357 43.4% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_CLPTM1 CTNND2 1501 genome.wustl.edu 37 5 11346575 11346575 + Nonsense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001332.2 -1 validated p.E513* 1.000 196 0% 177 34.5% 0 - - - - NULL ENSG00000249556 0 genome.wustl.edu 37 5 14652391 14652391 + RNA SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000515374 +1 novel NULL 1.000 38 0% 30 30% 606 0% - - - - PAIP1 10605 genome.wustl.edu 37 5 43529910 43529910 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006451.4 -1 reviewed p.D442N 1.000 294 0% 335 29.3% 4 25% possibly_damaging(0.786) tolerated(0.12) deleterious(0.555) NULL GPR98 84059 genome.wustl.edu 37 5 89990518 89990518 + Missense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032119.3 +1 reviewed p.G2649C 1.000 198 0.5% 182 33% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Calx-beta,HMMSmart_SM00237 ADAMTS19 171019 genome.wustl.edu 37 5 128796169 128796169 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_133638.3 +1 reviewed p.V23I 0.001 271 0% 220 30% 0 - benign(0.235) - - NULL C5orf15 56951 genome.wustl.edu 37 5 133304207 133304207 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020199.2 -1 validated p.I23 0.031 13 0% 19 52.6% 46 60.8% - - - NULL SEC24A 10802 genome.wustl.edu 37 5 134029434 134029434 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_021982.1 +1 validated p.L599 1.000 70 0% 69 36.2% 0 - - - - HMMPfam_Sec23_trunk,superfamily_vWA-like PKD2L2 27039 genome.wustl.edu 37 5 137257412 137257412 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014386.2 +1 validated p.I472 1.000 724 0% 977 33.8% 0 - - - - HMMPfam_PKD_channel PCDHA4 56144 genome.wustl.edu 37 5 140188298 140188298 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018907.2 +1 reviewed p.S509L 0.995 38 0% 28 17.9% 33 0% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like PCDHB3 56132 genome.wustl.edu 37 5 140482390 140482390 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018937.2 +1 reviewed p.A719 0.001 75 0% 54 20.4% 2 0% - - - NULL PCDHGA2 56113 genome.wustl.edu 37 5 140720331 140720331 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018915.2 +1 reviewed p.S598L 0.991 34 0% 29 27.6% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like PCDHGA10 56106 genome.wustl.edu 37 5 140794341 140794341 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018913.2 +1 reviewed p.Q533H 0.006 132 0% 127 37.8% 0 - benign(0.01) tolerated(0.08) neutral(0.300) HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like WWC1 23286 genome.wustl.edu 37 5 167850639 167850639 + Nonsense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015238.2 +1 reviewed p.S459* 1.000 69 0% 40 37.5% 37 18.9% - - - NULL EXOC2 55770 genome.wustl.edu 37 6 598888 598888 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018303.4 -1 reviewed p.G314 1.000 144 0% 182 38.5% 1 0% - - - NULL KIF13A 63971 genome.wustl.edu 37 6 17826044 17826044 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_022113.4 -1 validated p.E581Q 1.000 231 0% 197 36.5% 4 50% probably_damaging(0.996) tolerated(0.16) deleterious(0.521) NULL ARMC12 221481 genome.wustl.edu 37 6 35716402 35716402 + Nonsense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_145028.3 +1 predicted p.E287* 1.000 161 0% 100 36% 0 - - - - HMMPfam_DUF634,superfamily_ARM-type_fold ZUFSP 221302 genome.wustl.edu 37 6 116988183 116988183 + Missense_Mutation SNP A A C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_145062.2 -1 validated p.L58R 0.001 492 0% 569 32% 0 - benign(0.014) tolerated(0.38) neutral(0.018) NULL NMBR 4829 genome.wustl.edu 37 6 142409553 142409553 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002511.2 -1 validated p.F81 1.000 81 0% 59 33.9% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 AKAP12 9590 genome.wustl.edu 37 6 151673958 151673958 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005100.3 +1 reviewed p.D1478N 0.002 91 0% 90 28.9% 16 31.2% benign(0.001) tolerated(0.06) neutral(0.323) NULL TULP4 56995 genome.wustl.edu 37 6 158923300 158923300 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020245.3 +1 validated p.D869N 1.000 22 0% 11 45.5% 6 100% possibly_damaging(0.638) deleterious(0) deleterious(0.668) NULL LOC100132858 100132858 genome.wustl.edu 37 7 31131 31131 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 XM_001715131.2 -1 model p.P274S 0.286 46 0% 44 15.9% 1 0% - - - NULL CCDC129 223075 genome.wustl.edu 37 7 31617535 31617535 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_194300.2 +1 validated p.L219 1.000 89 0% 83 32.5% 0 - - - - NULL GPR141 353345 genome.wustl.edu 37 7 37780210 37780210 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_181791.1 +1 provisional p.R72H 0.996 167 0% 114 44.7% 1 0% probably_damaging(1) tolerated(0.08) deleterious(0.800) HMMPfam_7tm_1,superfamily_SSF81321 KCTD7 154881 genome.wustl.edu 37 7 66098391 66098391 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_153033.3 +1 validated p.E92K 0.998 84 0% 122 32% 7 14.2% benign(0.018) tolerated(0.07) neutral(0.320) HMMSmart_SM00225,HMMPfam_K_tetra,superfamily_POZ domain POR 5447 genome.wustl.edu 37 7 75583403 75583403 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000941.2 +1 reviewed p.M31I 0.000 256 0% 241 33.6% 47 38.2% benign(0) tolerated(1) - NULL PON1 5444 genome.wustl.edu 37 7 94931625 94931625 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000446.5 -1 reviewed p.L267 0.028 112 0% 113 36.3% 0 - - - - superfamily_Calcium-dependent phosphotriesterase GAL3ST4 79690 genome.wustl.edu 37 7 99758228 99758228 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024637.4 -1 reviewed p.P262A 0.540 18 0% 24 29.2% 17 35.2% probably_damaging(0.998) tolerated(0.29) deleterious(0.503) HMMPfam_Gal-3-0_sulfotr ZAN 7455 genome.wustl.edu 37 7 100374089 100374089 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003386.1 +1 reviewed p.M2073I 0.068 288 0% 283 39.6% 0 - unknown(0) tolerated(0.4) - NULL RBM28 55131 genome.wustl.edu 37 7 127965868 127965869 + Splice_Site INS - - A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 - - Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018077.2 -1 reviewed e11+2 0.991:1.000 - - - - - - - - - - CPA1 1357 genome.wustl.edu 37 7 130021554 130021554 + Silent SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001868.2 +1 reviewed p.I77 0.285 36 0% 42 35.7% 0 - - - - HMMPfam_Propep_M14,superfamily_Prot_inh_propept MGAM 8972 genome.wustl.edu 37 7 141719060 141719060 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004668.2 +1 reviewed p.C130Y 1.000 136 0% 132 41.7% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Trefoil KCNH2 3757 genome.wustl.edu 37 7 150649644 150649644 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000238.2 -1 reviewed p.V476I 1.000 131 0% 102 44.1% 28 32.1% possibly_damaging(0.584) deleterious(0.03) deleterious(0.566) HMMPfam_Ion_trans,superfamily_Voltage-gated potassium channels BLK 640 genome.wustl.edu 37 8 11418839 11418839 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001715.2 +1 validated p.R353H 0.021 104 0% 91 38.5% 6 0% benign(0) deleterious(0.01) neutral(0.406) HMMPfam_Pkinase_Tyr,HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like) MIR383 494332 genome.wustl.edu 37 8 14710954 14710954 + RNA SNP T T A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000362257 -1 known NULL 1.000 134 0% 115 29.6% 0 - - - - - KCNU1 157855 genome.wustl.edu 37 8 36793343 36793343 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001031836.2 +1 validated p.Q1119* 0.000 172 0% 153 35.3% 0 - - - - NULL ARFGEF1 10565 genome.wustl.edu 37 8 68151038 68151038 + Missense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006421.3 -1 reviewed p.D1024Y 1.000 500 0% 539 32.1% 10 0% probably_damaging(1) deleterious(0) deleterious(0.945) superfamily_ARM-type_fold ARFGEF1 10565 genome.wustl.edu 37 8 68163587 68163587 + Nonsense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006421.3 -1 reviewed p.Q933* 1.000 309 0% 356 38.2% 32 9.3% - - - superfamily_ARM-type_fold NCOA2 10499 genome.wustl.edu 37 8 71036975 71036975 + Nonsense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006540.2 -1 validated p.Q1348* 1.000 264 0% 185 37.3% 47 23.4% - - - NULL CSMD3 114788 genome.wustl.edu 37 8 113332145 113332145 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_198123.1 -1 validated p.D2411N 1.000 249 0% 349 34.7% 0 - benign(0.198) tolerated(0.23) neutral(0.060) HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain DENND4C 55667 genome.wustl.edu 37 9 19341013 19341013 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_017925.4 +1 provisional p.G684R 1.000 166 0% 200 32% 12 33.3% probably_damaging(0.988) deleterious(0.03) deleterious(0.802) NULL C9orf51 647044 genome.wustl.edu 37 9 38527179 38527179 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000377689 +1 known p.S29N 0.001 12 0% 13 38.5% 0 - possibly_damaging(0.85) tolerated(0.09) deleterious(0.623) NULL FAM75A6 389730 genome.wustl.edu 37 9 43627803 43627803 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001145196.1 -1 predicted p.S295L 0.001 39 0% 27 33.3% 0 - probably_damaging(0.999) tolerated(0.69) deleterious(0.492) NULL XPA 7507 genome.wustl.edu 37 9 100447258 100447258 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000380.3 -1 reviewed p.R207Q 1.000 679 0.1% 886 36.6% 1 100% probably_damaging(0.999) deleterious(0.02) deleterious(0.873) superfamily_Putativ_DNA_bind OR13F1 138805 genome.wustl.edu 37 9 107267278 107267278 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001004485.1 +1 provisional p.L245 0.996 210 0% 158 39.9% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 ZNF883 169834 genome.wustl.edu 37 9 115760054 115760054 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001101338.1 -1 validated p.F162 0.981 394 0% 410 35.9% 0 - - - - HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers CNTRL 11064 genome.wustl.edu 37 9 123858837 123858837 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007018.4 +1 reviewed p.S206L 1.000 292 0% 415 30.6% 1 100% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_LRR_1,HMMSmart_SM00369,HMMSmart_SM00365,superfamily_L domain-like C9orf50 375759 genome.wustl.edu 37 9 132381882 132381882 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_199350.3 -1 validated p.T211 0.003 227 0% 184 38% 0 - - - - NULL DDX31 64794 genome.wustl.edu 37 9 135501083 135501083 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_022779.7 -1 reviewed p.D666N 1.000 308 0% 342 31.3% 1 0% probably_damaging(0.969) tolerated(0.14) deleterious(0.661) NULL SNAPC4 6621 genome.wustl.edu 37 9 139272273 139272273 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003086.2 -1 validated p.E1336K 0.000 18 0.000 6 0.667 19 47.3% possibly_damaging(0.662) tolerated(0.07) deleterious(0.553) NULL OPTN 10133 genome.wustl.edu 37 10 13164418 13164418 + Silent SNP T T C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000424614 +1 known p.V87A 0.000 223 0% 226 29.6% 8 25% - - - NULL ACBD7 414149 genome.wustl.edu 37 10 15120550 15120550 + Silent SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001039844.2 -1 validated p.L82 1.000 313 0% 214 14% 1 0% - - - HMMPfam_ACBP,superfamily_Acyl-CoA binding protein RPP38 10557 genome.wustl.edu 37 10 15145710 15145710 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001097590.1 +1 validated p.L133 0.836 96 0% 54 13% 42 21.4% - - - HMMPfam_Ribosomal_L7Ae,superfamily_SSF55315 CUBN 8029 genome.wustl.edu 37 10 17171680 17171680 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001081.3 -1 reviewed p.E29Q 0.008 534 0% 333 52% 0 - probably_damaging(0.96) deleterious(0.04) deleterious(0.752) NULL FAS 355 genome.wustl.edu 37 10 90770355 90770355 + Frame_Shift_Del DEL A A - novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000043.3 +1 reviewed p.G169fs 0.509 - - - - - - - - - NULL PHRF1 57661 genome.wustl.edu 37 11 609285 609285 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020901.2 +1 validated p.D1276N 0.756 49 0% 39 15.4% 33 3% benign(0.025) deleterious(0) neutral(0.446) NULL ZNF195 7748 genome.wustl.edu 37 11 3381373 3381373 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001130520.1 -1 validated p.E289K 0.000 142 0% 184 35.3% 1 0% benign(0.002) tolerated(1) - superfamily_C2H2 and C2HC zinc fingers DBX1 120237 genome.wustl.edu 37 11 20178719 20178719 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001029865.1 -1 provisional p.R179Q 1.000 19 0% 10 80% 0 - probably_damaging(0.999) deleterious(0) deleterious(0.935) superfamily_Homeodomain-like MARK2 2011 genome.wustl.edu 37 11 63670132 63670132 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001039469.2 +1 reviewed p.A399T 0.982 68 0% 84 33.3% 26 46.1% benign(0.006) tolerated(0.24) neutral(0.037) NULL MRPL49 740 genome.wustl.edu 37 11 64893016 64893016 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004927.2 +1 reviewed p.V96I 1.000 212 0% 242 33.1% 103 52.4% probably_damaging(0.991) tolerated(0.06) deleterious(0.766) HMMPfam_Img2 TBX10 347853 genome.wustl.edu 37 11 67401671 67401671 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005995.3 -1 provisional p.D180N 1.000 34 0% 27 48.1% 0 - benign(0.17) deleterious(0.04) neutral(0.364) HMMPfam_T-box,HMMSmart_TBOX,superfamily_P53_like_DNA_bnd LRP5 4041 genome.wustl.edu 37 11 68201159 68201159 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002335.2 +1 reviewed p.E1285K 1.000 33 0% 17 35.3% 146 54.1% probably_damaging(0.994) tolerated(0.09) deleterious(0.748) HMMPfam_Ldl_recept_a,HMMSmart_SM00192,PatternScan_LDLRA_1,superfamily_LDL receptor-like module CCDC67 159989 genome.wustl.edu 37 11 93088706 93088706 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_181645.3 +1 validated p.E67Q 1.000 232 0% 199 33.7% 0 - probably_damaging(0.994) deleterious(0) deleterious(0.897) NULL EXPH5 23086 genome.wustl.edu 37 11 108384595 108384595 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015065.2 -1 validated p.E547Q 0.012 116 0% 112 40.2% 1 0% possibly_damaging(0.488) deleterious(0.01) deleterious(0.568) NULL DSCAML1 57453 genome.wustl.edu 37 11 117303143 117303143 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020693.2 -1 provisional p.V1762I 0.998 191 0% 151 34.4% 0 - possibly_damaging(0.893) tolerated(0.5) neutral(0.362) NULL MCAM 4162 genome.wustl.edu 37 11 119182786 119182786 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006500.2 -1 validated p.L373 0.759 39 0% 56 39.3% 25 12% - - - HMMSmart_SM00408,HMMSmart_SM00409,HMMPfam_ig,superfamily_Immunoglobulin TMEM225 338661 genome.wustl.edu 37 11 123755313 123755313 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001013743.1 -1 provisional p.T71M 0.001 215 0% 238 31.9% 0 - benign(0) tolerated(0.28) neutral(0.032) NULL GLB1L3 112937 genome.wustl.edu 37 11 134188824 134188824 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001080407.2 +1 validated p.K650 0.001 222 0% 221 44.8% 0 - - - - NULL ANO2 57101 genome.wustl.edu 37 12 5756964 5756964 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020373.2 -1 validated p.D517N 1.000 238 0% 243 35.8% 0 - benign(0.124) tolerated(0.23) neutral(0.052) NULL CASC1 55259 genome.wustl.edu 37 12 25307271 25307271 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018272.3 -1 validated p.K140 0.986 388 0% 433 36.3% 0 - - - - NULL IRAK4 51135 genome.wustl.edu 37 12 44166772 44166772 + Missense_Mutation SNP G G A rs186194251 by1000genomes TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001114182.2 +1 reviewed p.R183Q 0.998 240 0% 308 32.8% 4 50% possibly_damaging(0.638) tolerated(0.17) neutral(0.282) superfamily_Protein kinase-like (PK-like) SLC11A2 4891 genome.wustl.edu 37 12 51386088 51386088 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000617.2 -1 reviewed p.R411Q 1.000 174 0% 179 41.3% 87 47.1% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Nramp ENSG00000135477 0 genome.wustl.edu 37 12 52652235 52652235 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000257935 -1 known p.A35T 1.000 13 0% 15 46.7% 0 - - - - NULL ESPL1 9700 genome.wustl.edu 37 12 53677890 53677890 + Silent SNP T T C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_012291.4 +1 validated p.N1042 0.124 218 0% 219 41.6% 18 55.5% - - - NULL LOC100289011 100289011 genome.wustl.edu 37 12 54962946 54962946 + Missense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 XM_002343169.1 -1 model p.H57N 0.813 36 0% 20 20% 0 - unknown(0) deleterious(0) - NULL ERBB3 2065 genome.wustl.edu 37 12 56481612 56481612 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001982.2 +1 reviewed p.G216A 1.000 208 0% 155 42.6% 116 54.3% possibly_damaging(0.928) tolerated(0.21) neutral(0.419) HMMPfam_Furin-like,HMMSmart_SM00261,superfamily_Growth factor receptor domain GRIP1 23426 genome.wustl.edu 37 12 66814557 66814557 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_021150.3 -1 reviewed p.R542T 1.000 356 0% 371 38.3% 0 - possibly_damaging(0.864) deleterious(0.01) deleterious(0.740) HMMPfam_PDZ,HMMSmart_SM00228,superfamily_PDZ domain-like PARPBP 55010 genome.wustl.edu 37 12 102572517 102572517 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_017915.2 +1 predicted p.H304Y 0.000 299 0% 334 34.4% 3 66.6% benign(0) tolerated(1) - NULL IGF1 3479 genome.wustl.edu 37 12 102869441 102869441 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001111285.1 -1 reviewed p.G67E 1.000 53 0% 33 33.3% 6 0% probably_damaging(1) tolerated(0.27) deleterious(0.533) HMMPfam_Insulin,HMMSmart_SM00078,superfamily_Insulin-like VSIG10 54621 genome.wustl.edu 37 12 118533379 118533379 + Missense_Mutation SNP A A C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_019086.5 -1 validated p.L107R 0.994 125 0% 92 34.8% 14 64.2% probably_damaging(0.987) deleterious(0.04) deleterious(0.785) HMMSmart_SM00408,HMMSmart_SM00409,superfamily_Immunoglobulin GLT1D1 144423 genome.wustl.edu 37 12 129373189 129373189 + Nonsense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_144669.1 +1 provisional p.R75* 0.000 259 0% 264 32.2% 0 - - - - NULL ZNF140 7699 genome.wustl.edu 37 12 133683082 133683082 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003440.2 +1 validated p.H407Y 1.000 131 0% 171 29.8% 9 11.1% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 NAA16 79612 genome.wustl.edu 37 13 41899893 41899893 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024561.4 +1 validated p.V199 1.000 199 0% 264 37.9% 0 - - - - superfamily_TPR-like FAM194B 220081 genome.wustl.edu 37 13 46142541 46142541 + Nonsense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_182542.2 -1 predicted p.E366* 0.011 481 0% 563 37.1% 0 - - - - NULL PCDH17 27253 genome.wustl.edu 37 13 58298758 58298758 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001040429.2 +1 reviewed p.C937Y 1.000 54 0% 42 31% 1 0% possibly_damaging(0.95) deleterious(0.03) deleterious(0.758) NULL DIAPH3 81624 genome.wustl.edu 37 13 60407388 60407388 + Silent SNP T T G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001042517.1 -1 validated p.A960 0.926 236 0% 313 36.1% 6 33.3% - - - HMMSmart_SM00498,HMMPfam_FH2,superfamily_Formin homology 2 domain (FH2 domain) LOC643677 643677 genome.wustl.edu 37 13 103386886 103386886 + Silent SNP T T C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 XM_002344085.1 -1 model p.S5235 0.518 657 0% 630 37% 0 - - - - NULL SALL2 6297 genome.wustl.edu 37 14 22004984 22004984 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005407.1 -1 validated p.N24 1.000 89 0% 92 34.8% 0 - - - - NULL KIAA0391 9692 genome.wustl.edu 37 14 35592628 35592628 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014672.2 +1 provisional p.T59 0.000 150 0% 157 29.3% 2 100% - - - NULL KIAA0391 9692 genome.wustl.edu 37 14 35592755 35592755 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014672.2 +1 provisional p.D102N 0.018 66 0% 79 19% 7 57.1% benign(0.009) tolerated(0.38) neutral(0.018) NULL KIAA0391 9692 genome.wustl.edu 37 14 35593125 35593125 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014672.2 +1 provisional p.R225T 0.980 111 0% 101 32.7% 0 - probably_damaging(0.999) tolerated(0.06) deleterious(0.813) NULL NIN 51199 genome.wustl.edu 37 14 51224804 51224804 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020921.3 -1 reviewed p.E982K 0.987 101 1% 105 40% 1 100% possibly_damaging(0.455) tolerated(0.08) neutral(0.449) NULL FERMT2 10979 genome.wustl.edu 37 14 53347766 53347766 + Missense_Mutation SNP A A C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001134999.1 -1 validated p.D281E 1.000 228 0% 235 35.7% 4 25% probably_damaging(0.998) deleterious(0.02) deleterious(0.857) HMMPfam_FERM_M,superfamily_FERM_3-hlx,HMMSmart_B41 LTBP2 4053 genome.wustl.edu 37 14 74975349 74975349 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000428.2 -1 reviewed p.A1204T 0.987 43 0% 27 44.4% 31 9.6% possibly_damaging(0.743) tolerated(0.08) deleterious(0.573) HMMSmart_SM00179,HMMSmart_SM00181,PatternScan_EGF_2,HMMPfam_EGF_CA,superfamily_EGF/Laminin CEP128 145508 genome.wustl.edu 37 14 81244378 81244378 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_152446.3 -1 validated p.E742Q 1.000 136 0% 123 47.2% 0 - possibly_damaging(0.875) tolerated(0.51) neutral(0.349) NULL TUBGCP5 114791 genome.wustl.edu 37 15 22864282 22864282 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001102610.1 +1 validated p.R747K 1.000 196 0% 211 29.9% 1 0% benign(0.291) tolerated(0.85) neutral(0.090) HMMPfam_Spc97_Spc98 LOC728310 728310 genome.wustl.edu 37 15 29088506 29088523 + RNA DEL CTCCTGATCCCGTAGCTC CTCCTGATCCCGTAGCTC - novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 CTCCTGATCCCGTAGCTC CTCCTGATCCCGTAGCTC Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 XR_078490.1 -1 model NULL 0.220:0.284:0.294:0.271:0.220:0.227:0.201:0.214:0.229:0.214:0.212:0.219:0.322:0.587:0.890:0.940:0.965:0.985 - - - - - - - - - - RYR3 6263 genome.wustl.edu 37 15 34102823 34102823 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001036.3 +1 validated p.I3390M 1.000 118 0% 86 31.4% 0 - possibly_damaging(0.606) - - NULL ZFP106 64397 genome.wustl.edu 37 15 42720288 42720288 + Silent SNP G G A rs11544099 byCluster;byFrequency;by1000genomes TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_022473.1 -1 provisional p.L1619 1.000 148 0% 106 27.4% 13 30.7% - - - superfamily_WD40_like CEP152 22995 genome.wustl.edu 37 15 49036482 49036482 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014985.2 -1 provisional p.E1208K 1.000 148 0% 149 20.8% 1 100% probably_damaging(0.971) deleterious(0.04) deleterious(0.762) NULL AP4E1 23431 genome.wustl.edu 37 15 51242333 51242333 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007347.3 +1 validated p.F505L 0.048 289 0% 286 42.3% 1 100% benign(0) tolerated(0.64) neutral(0.003) HMMPfam_Adaptin_N,superfamily_ARM-type_fold SKOR1 390598 genome.wustl.edu 37 15 68124682 68124682 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001031807.1 +1 provisional p.L842 1.000 147 0% 130 33.8% 0 - - - - NULL ABHD2 11057 genome.wustl.edu 37 15 89698680 89698680 + Missense_Mutation SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007011.7 +1 reviewed p.Q151H 1.000 160 0% 126 38.9% 67 44.7% benign(0.19) deleterious(0.02) neutral(0.401) superfamily_SSF53474 FAM174B 400451 genome.wustl.edu 37 15 93198572 93198572 + Silent SNP G G T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_207446.2 -1 validated p.I106 1.000 23 0% 25 56% 54 66.6% - - - HMMPfam_DUF1180 EME2 197342 genome.wustl.edu 37 16 1825808 1825808 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001010865.1 +1 provisional p.E329K 0.992 44 0% 50 22% 3 33.3% probably_damaging(0.975) deleterious(0.04) deleterious(0.766) HMMPfam_ERCC4 TIGD7 91151 genome.wustl.edu 37 16 3349103 3349103 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_033208.2 -1 validated p.L504 0.981 188 0% 271 50.2% 2 0% - - - NULL GRIN2A 2903 genome.wustl.edu 37 16 9857895 9857895 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000833.3 -1 reviewed p.R1169Q 1.000 165 0% 184 25.5% 0 - possibly_damaging(0.805) tolerated(0.41) neutral(0.318) HMMPfam_NMDAR2_C ITGAX 3687 genome.wustl.edu 37 16 31384633 31384633 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000887.3 +1 reviewed p.D810 0.977 117 0% 131 20.6% 36 0% - - - HMMPfam_Integrin_alpha2,superfamily_SSF69179 PHKB 5257 genome.wustl.edu 37 16 47732443 47732443 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000293.2 +1 reviewed p.E1030K 1.000 118 0% 217 23.5% 13 30.7% probably_damaging(0.996) tolerated(0.21) deleterious(0.506) HMMPfam_PHK_AB FOXC2 2303 genome.wustl.edu 37 16 86601025 86601025 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005251.2 +1 reviewed p.A28 0.410 28 0% 16 87.5% 0 - - - - NULL SGSM2 9905 genome.wustl.edu 37 17 2280296 2280296 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014853.2 +1 validated p.M912I 1.000 88 0% 76 50% 75 42.6% possibly_damaging(0.837) deleterious(0.01) deleterious(0.725) HMMPfam_TBC,HMMSmart_TBC,superfamily_RabGAP_TBC C17orf85 55421 genome.wustl.edu 37 17 3721643 3721643 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001114118.1 -1 provisional p.L408 1.000 129 0% 116 41.4% 6 50% - - - NULL ZMYND15 84225 genome.wustl.edu 37 17 4644179 4644179 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001136046.1 +1 provisional p.G112 0.985 72 0% 78 43.6% 1 100% - - - NULL DVL2 1856 genome.wustl.edu 37 17 7130433 7130433 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004422.2 -1 reviewed p.D507N 1.000 102 0% 81 11.1% 91 4.3% probably_damaging(1) deleterious(0.04) deleterious(0.849) "HMMSmart_SM00049,superfamily_""Winged helix"" DNA-binding domain" CNTROB 116840 genome.wustl.edu 37 17 7851917 7851917 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000380262 +1 known p.L831 1.000 279 0.4% 215 34.9% 26 42.3% - - - NULL MYH10 4628 genome.wustl.edu 37 17 8492423 8492423 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005964.1 -1 validated p.R169H 1.000 277 0% 321 34% 3 0% possibly_damaging(0.931) tolerated(0.07) deleterious(0.697) HMMPfam_Myosin_head,HMMSmart_SM00242,superfamily_P-loop containing nucleoside triphosphate hydrolases MYH3 4621 genome.wustl.edu 37 17 10545570 10545570 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002470.2 -1 reviewed p.S649C 1.000 170 0% 125 37.6% 0 - probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_Myosin_head,HMMSmart_MYSc,superfamily_SSF52540 LOC100128006 100128006 genome.wustl.edu 37 17 12664059 12664059 + RNA SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 XR_078523.1 -1 model NULL 0.000 195 0% 179 34.6% 0 - - - - - ENSG00000251558 0 genome.wustl.edu 37 17 26206277 26206277 + RNA SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000502259 +1 known NULL 0.825 14 0% 19 26.3% 0 - - - - - SEBOX 645832 genome.wustl.edu 37 17 26691495 26691495 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001080837.2 -1 validated p.S149L 0.002 242 0% 211 35.5% 0 - probably_damaging(0.98) deleterious(0.04) deleterious(0.773) NULL ARL4D 379 genome.wustl.edu 37 17 41477351 41477351 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001661.3 +1 reviewed p.R84Q 1.000 70 0% 56 41.1% 22 59% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00173,HMMSmart_SM00175,HMMSmart_SM00178,HMMSmart_SM00177,HMMPfam_Arf,superfamily_P-loop containing nucleoside triphosphate hydrolases CD300LG 146894 genome.wustl.edu 37 17 41931389 41931389 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_145273.3 +1 validated p.L232 0.928 61 0% 38 44.7% 0 - - - - NULL DGKE 8526 genome.wustl.edu 37 17 54939507 54939507 + Silent SNP C C T rs148695016 by1000genomes TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003647.2 +1 reviewed p.D473 0.988 225 0.9% 303 32.7% 11 27.2% - - - HMMPfam_DAGK_acc,HMMSmart_SM00045 OTOP2 92736 genome.wustl.edu 37 17 72921753 72921753 + Missense_Mutation SNP A A G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_178160.2 +1 validated p.H139R 0.998 164 0% 111 42.3% 1 0% possibly_damaging(0.704) deleterious(0.05) deleterious(0.599) NULL SMCHD1 23347 genome.wustl.edu 37 18 2656168 2656168 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015295.2 +1 validated p.D32H 1.000 44 0% 39 12.8% 1 0% probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL CEP192 55125 genome.wustl.edu 37 18 13015357 13015357 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000506447 +1 known p.E184K 0.137 316 0% 291 33.7% 0 - possibly_damaging(0.93) deleterious(0.02) deleterious(0.760) NULL ANKRD30B 374860 genome.wustl.edu 37 18 14748608 14748608 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001145029.1 +1 validated p.V64I 0.000 72 0% 48 35.4% 0 - benign(0.004) tolerated(1) - superfamily_Ankyrin repeat LOXHD1 125336 genome.wustl.edu 37 18 44087609 44087609 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001145472.2 -1 reviewed p.R751W 0.980 148 0.7% 134 30.6% 0 - possibly_damaging(0.908) deleterious(0.02) deleterious(0.744) superfamily_Lipase/lipooxygenase domain (PLAT/LH2 domain) ZNF407 55628 genome.wustl.edu 37 18 72344821 72344821 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_017757.2 +1 reviewed p.L616V 0.000 149 0% 97 38.1% 1 100% possibly_damaging(0.527) tolerated(0.07) deleterious(0.497) HMMSmart_SM00451,HMMSmart_SM00355 MUC16 94025 genome.wustl.edu 37 19 9015661 9015661 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024690.2 -1 validated p.S12721F 0.036 564 0% 478 34.1% 71 49.2% probably_damaging(0.996) - - HMMPfam_SEA,superfamily_SEA domain MUC16 94025 genome.wustl.edu 37 19 9062695 9062695 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024690.2 -1 validated p.D8251N 0.000 133 0% 96 40.6% 9 66.6% unknown(0) - - NULL MUC16 94025 genome.wustl.edu 37 19 9071910 9071910 + Missense_Mutation SNP T T C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_024690.2 -1 validated p.N5179S 0.000 367 0% 310 36.1% 6 33.3% unknown(0) - - NULL LDLR 3949 genome.wustl.edu 37 19 11238760 11238760 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_000527.3 +1 reviewed p.I796 0.022 119 0% 86 23.3% 115 40.8% - - - NULL ZNF443 10224 genome.wustl.edu 37 19 12543962 12543962 + Missense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005815.4 -1 validated p.W18L 1.000 502 0% 475 17.5% 2 50% probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352) HOOK2 29911 genome.wustl.edu 37 19 12874404 12874404 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_013312.2 -1 validated p.E650Q 1.000 175 0% 138 30.4% 72 45.8% benign(0.259) deleterious(0.03) neutral(0.392) HMMPfam_HOOK CPAMD8 27151 genome.wustl.edu 37 19 17086035 17086035 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_015692.2 -1 validated p.D695H 1.000 95 0% 80 42.5% 11 9% possibly_damaging(0.767) tolerated(0.22) neutral(0.326) NULL CRTC1 23373 genome.wustl.edu 37 19 18882289 18882289 + Missense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001098482.1 +1 validated p.S469Y 1.000 100 0% 55 27.3% 20 40% probably_damaging(0.998) tolerated(0.52) deleterious(0.483) NULL UPF1 5976 genome.wustl.edu 37 19 18965998 18965998 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002911.3 +1 reviewed p.G497 0.908 30 0% 41 24.4% 120 33.3% - - - HMMPfam_ResIII,superfamily_SSF52540 ZNF181 339318 genome.wustl.edu 37 19 35232054 35232054 + Nonsense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001029997.3 +1 validated p.W256* 0.832 175 0% 172 23.3% 6 33.3% - - - HMMSmart_SM00614,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers ACTN4 81 genome.wustl.edu 37 19 39214715 39214715 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_004924.3 +1 reviewed p.E564K 1.000 47 0% 40 35% 394 37.5% unknown(0) tolerated(0.31) - HMMPfam_Spectrin,HMMSmart_SPEC,superfamily_Spectrin MIR330 442902 genome.wustl.edu 37 19 46142270 46142270 + RNA SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000362196 -1 known NULL 1.000 49 0% 40 30% 1 0% - - - - POLD1 5424 genome.wustl.edu 37 19 50905595 50905595 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_002691.2 +1 validated p.F241 0.700 31 0% 20 40% 132 41.6% - - - HMMPfam_DNA_pol_B_exo,superfamily_RNaseH_fold USP29 57663 genome.wustl.edu 37 19 57640818 57640818 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020903.2 +1 validated p.E259K 0.000 152 0% 159 39% 0 - benign(0.018) tolerated(0.12) neutral(0.261) NULL PSMF1 9491 genome.wustl.edu 37 20 1108137 1108137 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006814.3 +1 reviewed p.L117 0.598 179 0% 195 20% 265 27.1% - - - NULL SIRPG 55423 genome.wustl.edu 37 20 1616211 1616211 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018556.3 -1 reviewed p.M261I 0.003 189 0% 233 19.3% 6 0% benign(0.001) tolerated(0.49) neutral(0.011) HMMPfam_C1-set,HMMSmart_SM00409,superfamily_Immunoglobulin ATRN 8455 genome.wustl.edu 37 20 3529829 3529829 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_139321.2 +1 reviewed p.S319L 0.998 410 0% 639 22.7% 29 31% benign(0.362) deleterious(0) deleterious(0.559) superfamily_Galactose oxidase central domain ATRN 8455 genome.wustl.edu 37 20 3581607 3581607 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_139321.2 +1 reviewed p.L1193F 1.000 160 0% 242 22.7% 65 23% probably_damaging(0.994) tolerated(0.13) deleterious(0.705) NULL E2F1 1869 genome.wustl.edu 37 20 32265234 32265234 + Missense_Mutation SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005225.2 -1 reviewed p.E280Q 0.922 140 0% 146 28.1% 59 47.4% probably_damaging(0.97) deleterious(0.01) deleterious(0.818) NULL RALGAPB 57148 genome.wustl.edu 37 20 37146448 37146448 + Missense_Mutation SNP A A G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_020336.2 +1 validated p.K408E 0.997 337 0% 450 51.1% 19 63.1% benign(0) tolerated(0.97) - NULL CHD6 84181 genome.wustl.edu 37 20 40074344 40074344 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032221.3 -1 reviewed p.E1280K 1.000 121 0.8% 167 36.5% 16 31.2% probably_damaging(0.976) tolerated(0.06) deleterious(0.740) NULL ARFGEF2 10564 genome.wustl.edu 37 20 47591368 47591368 + Nonsense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006420.2 +1 reviewed p.W577* 1.000 182 0% 212 28.8% 13 7.6% - - - superfamily_ARM-type_fold CBLN4 140689 genome.wustl.edu 37 20 54579031 54579031 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_080617.4 -1 reviewed p.A66V 1.000 98 0% 96 27.1% 0 - possibly_damaging(0.597) tolerated(0.05) deleterious(0.552) HMMSmart_C1Q KCNQ2 3785 genome.wustl.edu 37 20 62062712 62062712 + Missense_Mutation SNP G G C novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_172107.2 -1 reviewed p.Q377E 1.000 259 0% 357 27.5% 0 - benign(0.032) tolerated(1) neutral(0.002) NULL SLC19A1 6573 genome.wustl.edu 37 21 46951483 46951483 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_194255.1 -1 validated p.E257K 1.000 13 0% 11 36.4% 6 66.6% probably_damaging(0.961) deleterious(0.01) deleterious(0.810) HMMPfam_Folate_carrier,superfamily_MFS general substrate transporter KLHL22 84861 genome.wustl.edu 37 22 20812233 20812233 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_032775.2 -1 validated p.H389 0.991 85 0% 62 32.3% 215 39% - - - HMMPfam_Kelch_1,HMMSmart_SM00612,superfamily_Galactose oxidase central domain GGA1 26088 genome.wustl.edu 37 22 38017654 38017654 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_013365.4 +1 reviewed p.P187L 1.000 69 0% 65 32.3% 15 53.3% probably_damaging(0.999) deleterious(0) deleterious(0.935) superfamily_GAT-like domain SMCR7L 54471 genome.wustl.edu 37 22 39910028 39910028 + Silent SNP C C G novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_019008.4 +1 validated p.L364 1.000 62 0% 32 18.8% 54 46.2% - - - NULL PRR5 55615 genome.wustl.edu 37 22 45128211 45128211 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000455389 +1 known p.R125H 0.945 13 0% 12 58.3% 53 33.9% - - - HMMPfam_HbrB FBLN1 2192 genome.wustl.edu 37 22 45937131 45937131 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_006486.2 +1 reviewed p.I315 0.814 154 0% 124 42.7% 293 30.3% - - - HMMSmart_SM00179,HMMSmart_SM00181,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin CELSR1 9620 genome.wustl.edu 37 22 46930005 46930005 + Silent SNP A A T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 ENST00000454637 -1 known p.F396Y 0.909 106 0% 91 40.7% 82 54.8% - - - HMMPfam_Cadherin,HMMSmart_SM00112,superfamily_Cadherin-like BRD1 23774 genome.wustl.edu 37 22 50216880 50216880 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_014577.1 -1 reviewed p.M362I 1.000 99 0% 77 41.6% 34 29.4% possibly_damaging(0.786) deleterious(0) deleterious(0.739) HMMSmart_PHD FTHL17 53940 genome.wustl.edu 37 X 31089692 31089692 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_031894.2 -1 reviewed p.D127N 0.977 115 0% 83 22.9% 0 - probably_damaging(0.997) deleterious(0) deleterious(0.911) HMMPfam_Ferritin,superfamily_Ferritin/RR_like,PatternScan_FERRITIN_2 SLC35A2 7355 genome.wustl.edu 37 X 48767112 48767112 + Silent SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_005660.1 -1 provisional p.L85 1.000 99 0% 81 30.9% 127 92.9% - - - NULL ZXDB 158586 genome.wustl.edu 37 X 57619771 57619771 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007157.3 +1 validated p.G430 0.998 289 0% 191 34.6% 6 100% - - - HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355 NLGN3 54413 genome.wustl.edu 37 X 70389105 70389105 + Missense_Mutation SNP G G A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_018977.3 +1 reviewed p.D549N 1.000 66 0% 44 22.7% 0 - benign(0.38) tolerated(0.35) neutral(0.142) HMMPfam_COesterase,superfamily_SSF53474 NOX1 27035 genome.wustl.edu 37 X 100117472 100117472 + Nonsense_Mutation SNP C C A novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_007052.4 -1 reviewed p.E194* 1.000 127 0% 114 30.7% 0 - - - - HMMPfam_Ferric_reduct IRS4 8471 genome.wustl.edu 37 X 107977583 107977583 + Silent SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_003604.2 -1 reviewed p.T664 0.006 432 0% 427 30.4% 0 - - - - NULL FLNA 2316 genome.wustl.edu 37 X 153580678 153580678 + Missense_Mutation SNP C C T novel TCGA-D1-A16J-01A-11D-A12J-09 TCGA-D1-A16J-10A-01D-A12J-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx b1ed2aa0-e041-4446-ada3-0e9f45371b4d b4075a15-13b0-4664-a1f9-6a239276e6e9 NM_001110556.1 -1 reviewed p.V2214M 1.000 123 0% 106 27.4% 306 0.6% probably_damaging(0.989) deleterious(0) deleterious(0.884) HMMSmart_SM00557,superfamily_E set domains,HMMPfam_Filamin