Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID transcript_name strand transcript_status amino_acid_change ucsc_cons normal_depth normal_vaf tumor_depth tumor_vaf rna_depth rna_vaf polyphen sift condel domain EXOSC10 5394 genome.wustl.edu 37 1 11158135 11158135 + Nonsense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001001998.1 -1 validated p.R64* 1.000 106 0% 127 28.3% 1 100% - - - HMMPfam_PMC2NT PUM1 9698 genome.wustl.edu 37 1 31465245 31465245 + Nonsense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001020658.1 -1 reviewed p.Q384* 1.000 256 0% 520 32.1% 5 20% - - - NULL COL16A1 1307 genome.wustl.edu 37 1 32157635 32157635 + Missense_Mutation SNP T T G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001856.3 -1 reviewed p.K410Q 1.000 51 0% 41 41.5% 2 0% unknown(0) tolerated(0.09) - HMMPfam_Collagen USP33 23032 genome.wustl.edu 37 1 78207369 78207369 + Missense_Mutation SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_015017.3 -1 validated p.R36Q 0.997 80 0% 78 35.9% 0 - possibly_damaging(0.516) tolerated(0.05) deleterious(0.519) NULL DPYD 1806 genome.wustl.edu 37 1 98058899 98058899 + Missense_Mutation SNP C C T rs72549306 byCluster TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000110.3 -1 reviewed p.V335M 1.000 134 0% 153 50.3% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Pyr_redox_2,superfamily_SSF51971 STXBP3 6814 genome.wustl.edu 37 1 109340814 109340814 + Silent SNP T T C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_007269.2 +1 validated p.T468 0.829 326 0% 356 45.2% 10 40% - - - HMMPfam_Sec1,superfamily_Sec1-like BCL2L15 440603 genome.wustl.edu 37 1 114429241 114429241 + Missense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001010922.2 -1 validated p.R56P 1.000 124 0% 187 43.3% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) NULL CEP350 9857 genome.wustl.edu 37 1 180000560 180000560 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_014810.4 +1 reviewed p.S1219Y 0.406 55 0% 101 23.8% 0 - probably_damaging(0.955) deleterious(0) deleterious(0.843) NULL TPR 7175 genome.wustl.edu 37 1 186331435 186331435 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_003292.2 -1 reviewed p.L258 1.000 90 0% 88 36.4% 0 - - - - NULL SERTAD4 56256 genome.wustl.edu 37 1 210415592 210415592 + Missense_Mutation SNP T T G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_019605.3 +1 validated p.N327K 0.488 122 0% 115 46.1% 0 - benign(0.026) tolerated(1) neutral(0.001) NULL OBSCN 84033 genome.wustl.edu 37 1 228461239 228461239 + Missense_Mutation SNP C C T rs189809636 by1000genomes TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001098623.1 +1 reviewed p.H1710Y 0.763 8 0.000 9 0.667 0 - benign(0.025) deleterious(0.05) neutral(0.346) HMMSmart_SM00406,HMMSmart_SM00409,superfamily_Immunoglobulin LOC644006 644006 genome.wustl.edu 37 1 231157656 231157656 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e XM_929433.4 +1 model p.L100F 0.924 65 0% 76 52.6% 0 - - - - NULL APOB 338 genome.wustl.edu 37 2 21235038 21235038 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000384.2 -1 reviewed p.L1568M 0.999 211 0% 395 31.1% 0 - probably_damaging(0.991) - - NULL ATAD2B 54454 genome.wustl.edu 37 2 24033196 24033196 + Nonsense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_017552.1 -1 validated p.S815* 1.000 53 0% 127 30.7% 0 - - - - superfamily_P-loop containing nucleoside triphosphate hydrolases OTOF 9381 genome.wustl.edu 37 2 26725223 26725223 + Missense_Mutation SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_194248.2 -1 reviewed p.D219N 1.000 31 0% 65 35.4% 0 - probably_damaging(0.959) deleterious(0) deleterious(0.847) NULL BIRC6 57448 genome.wustl.edu 37 2 32733118 32733118 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_016252.3 +1 reviewed p.V3258F 1.000 99 0% 197 22.8% 1 0% benign(0.002) tolerated(0.05) neutral(0.345) superfamily_Galactose-binding domain-like MSH2 4436 genome.wustl.edu 37 2 47657080 47657089 + Frame_Shift_Del DEL GGTAACAAGT GGTAACAAGT - novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 GGTAACAAGT GGTAACAAGT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000251.1 +1 reviewed p.G426fs 1.000 - - - - - - - - - HMMPfam_MutS_III,HMMSmart_MUTSd,superfamily_DNA_repair_MutS_domIII USP19 10869 genome.wustl.edu 37 3 49154344 49154344 + Silent SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_006677.1 -1 provisional p.P213 0.003 49 0% 40 52.5% 2 0% - - - HMMPfam_DUF1872 SLMAP 7871 genome.wustl.edu 37 3 57857375 57857375 + Nonsense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_007159.2 +1 validated p.S383* 1.000 107 0% 120 38.3% 0 - - - - NULL ATXN7 6314 genome.wustl.edu 37 3 63973759 63973759 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001128149.2 +1 reviewed p.A374S 1.000 425 0% 403 44.7% 0 - probably_damaging(0.999) deleterious(0.04) deleterious(0.839) HMMPfam_SCA7 POLQ 10721 genome.wustl.edu 37 3 121200581 121200581 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_199420.3 -1 validated p.L2017I 0.999 164 0% 208 36.1% 1 0% probably_damaging(0.978) deleterious(0.04) deleterious(0.769) superfamily_Ribonuclease H-like NPHP3 27031 genome.wustl.edu 37 3 132413683 132413683 + Missense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_153240.3 -1 reviewed p.E766D 0.192 240 0% 252 42.9% 0 - benign(0) tolerated(0.09) neutral(0.296) NULL PEX5L 51555 genome.wustl.edu 37 3 179576911 179576911 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_016559.1 -1 provisional p.A254G 0.989 198 0% 216 44.9% 0 - benign(0.111) tolerated(0.06) neutral(0.331) NULL MUC20 200958 genome.wustl.edu 37 3 195460044 195460044 + Missense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_152673.2 +1 reviewed p.H524Q 0.000 29 0% 38 15.8% 119 0.8% possibly_damaging(0.873) tolerated(0.45) neutral(0.351) NULL FBXW7 55294 genome.wustl.edu 37 4 153249384 153249384 + Missense_Mutation SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_033632.2 -1 reviewed p.R465H 1.000 341 0% 392 44.6% 1 0% probably_damaging(1) deleterious(0) deleterious(0.945) HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40 STOX2 56977 genome.wustl.edu 37 4 184938282 184938282 + Missense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_020225.1 +1 provisional p.E876K 1.000 60 0% 55 50.9% 0 - probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL LPCAT1 79888 genome.wustl.edu 37 5 1463855 1463855 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_024830.3 -1 validated p.P506T 0.000 129 0% 148 36.5% 4 0% benign(0.001) deleterious(0.03) neutral(0.364) NULL RAI14 26064 genome.wustl.edu 37 5 34824014 34824014 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001145525.1 +1 validated p.N692 0.000 158 0% 208 37% 2 50% - - - NULL VCAN 1462 genome.wustl.edu 37 5 82815532 82815532 + Nonsense_Mutation SNP T T A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_004385.4 +1 reviewed p.Y469* 0.236 228 0% 293 48.5% 0 - - - - NULL PCDHB16 57717 genome.wustl.edu 37 5 140562499 140562499 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_020957.1 +1 reviewed p.R122M 0.000 95 2.1% 89 38.2% 0 - benign(0.002) tolerated(0.06) neutral(0.323) PatternScan_CADHERIN_1,superfamily_Cadherin OR12D3 81797 genome.wustl.edu 37 6 29236369 29236369 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000396806 -1 known p.S273I 0.000 102 0% 123 51.2% 0 - - - - HMMPfam_7tm_1,superfamily_SSF81321 NOTCH4 4855 genome.wustl.edu 37 6 32163293 32163293 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_004557.3 -1 reviewed p.R1978L 0.013 212 0% 192 41.1% 1 100% possibly_damaging(0.83) deleterious(0) deleterious(0.760) NULL RING1 6015 genome.wustl.edu 37 6 33178980 33178980 + Silent SNP A A C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_002931.3 +1 reviewed p.T167 0.938 397 0% 292 40.1% 3 66.6% - - - NULL GRIK2 2898 genome.wustl.edu 37 6 102503408 102503408 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_021956.4 +1 reviewed p.V839L 1.000 280 0% 265 39.6% 0 - benign(0.045) tolerated(0.15) neutral(0.243) HMMPfam_Lig_chan COL10A1 1300 genome.wustl.edu 37 6 116442361 116442361 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000493.3 -1 reviewed p.L306 0.253 54 0% 51 52.9% 1 0% - - - NULL MAP3K5 4217 genome.wustl.edu 37 6 136972140 136972140 + Silent SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_005923.3 -1 reviewed p.H590 0.785 22 0% 25 56% 1 0% - - - NULL UTRN 7402 genome.wustl.edu 37 6 144835132 144835132 + Missense_Mutation SNP A A C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_007124.2 +1 reviewed p.I1678L 1.000 199 0% 214 43.9% 0 - possibly_damaging(0.663) tolerated(0.51) neutral(0.243) HMMPfam_Spectrin,superfamily_Spectrin SYTL3 94120 genome.wustl.edu 37 6 159084345 159084345 + Silent SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001009991.2 +1 validated p.R15 0.632 53 0% 58 46.6% 0 - - - - superfamily_FYVE/PHD zinc finger FNDC1 84624 genome.wustl.edu 37 6 159650865 159650865 + Missense_Mutation SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_032532.2 +1 validated p.A400V 1.000 427 0% 425 40.7% 0 - unknown(0) deleterious(0.04) - HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like SCIN 85477 genome.wustl.edu 37 7 12689092 12689092 + Missense_Mutation SNP A A T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001112706.2 +1 validated p.I628F 1.000 25 0% 24 37.5% 0 - possibly_damaging(0.931) deleterious(0.01) deleterious(0.783) HMMSmart_SM00262,HMMPfam_Gelsolin,superfamily_Actin depolymerizing proteins SSPO 23145 genome.wustl.edu 37 7 149492657 149492657 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000378016 +1 known p.N2146S 0.001 27 0% 33 33.3% 0 - - - - HMMPfam_F5_F8_type_C,HMMSmart_SM00231,superfamily_Galactose-binding domain-like ABP1 26 genome.wustl.edu 37 7 150554356 150554356 + Silent SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001091.2 +1 reviewed p.P266 0.000 37 0% 34 41.2% 7 42.8% - - - superfamily_Amine oxidase N-terminal region CSMD3 114788 genome.wustl.edu 37 8 113293531 113293531 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_198123.1 -1 validated p.R3127L 1.000 104 0% 149 28.9% 0 - probably_damaging(0.997) tolerated(0.57) deleterious(0.472) HMMPfam_Sushi,HMMSmart_SM00032,superfamily_Complement control module/SCR domain CSMD3 114788 genome.wustl.edu 37 8 114111160 114111160 + Missense_Mutation SNP A A T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_198123.1 -1 validated p.S248T 1.000 94 0% 229 30.1% 0 - unknown(0) tolerated(0.75) - HMMPfam_CUB,HMMSmart_SM00042,superfamily_Spermadhesin CUB domain UGCG 7357 genome.wustl.edu 37 9 114695230 114695230 + Missense_Mutation SNP T T A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_003358.1 +1 reviewed p.Y380N 1.000 142 0% 190 30.5% 1 0% possibly_damaging(0.678) deleterious(0) deleterious(0.686) NULL LOC645954 645954 genome.wustl.edu 37 10 31001498 31001498 + RNA SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e XR_017086.3 +1 model NULL 0.988 63 0% 99 46.5% 0 - - - - - LRRC20 55222 genome.wustl.edu 37 10 72061120 72061120 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_207119.1 -1 validated p.P182H 0.037 61 0% 90 30% 1 0% possibly_damaging(0.677) deleterious(0) deleterious(0.685) NULL PLCE1 51196 genome.wustl.edu 37 10 95790936 95790936 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_016341.3 +1 reviewed p.R45G 0.000 286 0% 290 41.4% 0 - benign(0.01) deleterious(0) neutral(0.445) NULL NOLC1 9221 genome.wustl.edu 37 10 103917208 103917208 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_004741.3 +1 validated p.G113R 0.000 89 0% 112 45.5% 5 20% unknown(0) deleterious(0.03) - NULL FAM160B1 57700 genome.wustl.edu 37 10 116606408 116606408 + Nonsense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_020940.3 +1 validated p.E497* 1.000 238 0% 264 50.4% 0 - - - - NULL PTPRJ 5795 genome.wustl.edu 37 11 48146705 48146705 + Nonsense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_002843.3 +1 reviewed p.E354* 0.458 116 0% 131 46.6% 5 0% - - - HMMSmart_FN3 C11orf9 745 genome.wustl.edu 37 11 61539128 61539128 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001127392.1 +1 validated p.P299 0.999 114 0% 72 44.4% 0 - - - - NULL SLC22A25 387601 genome.wustl.edu 37 11 62995935 62995935 + Missense_Mutation SNP G G T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_199352.3 -1 validated p.D168E 1.000 151 0% 180 36.1% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_MFS_1,superfamily_MFS general substrate transporter SYVN1 84447 genome.wustl.edu 37 11 64900985 64900985 + Missense_Mutation SNP A A T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_172230.2 -1 reviewed p.Y30N 1.000 59 0% 76 35.5% 8 37.5% probably_damaging(0.999) deleterious(0) deleterious(0.935) NULL RNF214 257160 genome.wustl.edu 37 11 117152119 117152119 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001077239.1 +1 validated p.R412P 1.000 235 0% 216 48.1% 7 71.4% probably_damaging(0.97) deleterious(0.01) deleterious(0.818) NULL CHD4 1108 genome.wustl.edu 37 12 6701600 6701600 + Missense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001273.2 -1 reviewed p.K969N 1.000 331 0.3% 408 59.1% 6 50% probably_damaging(0.998) deleterious(0) deleterious(0.919) HMMPfam_SNF2_N MCRS1 10445 genome.wustl.edu 37 12 49953511 49953511 + Splice_Site SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001012300.1 -1 validated e10+1 1.000 47 0% 43 41.9% 2 100% - - - - ACVR1B 91 genome.wustl.edu 37 12 52379078 52379078 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_004302.3 +1 reviewed p.D361G 0.996 118 0% 138 25.4% 2 0% probably_damaging(0.961) tolerated(0.1) deleterious(0.691) HMMSmart_SM00219,HMMSmart_SM00220,superfamily_Protein kinase-like (PK-like),HMMPfam_Pkinase CCT2 10576 genome.wustl.edu 37 12 69990984 69990984 + Missense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_006431.2 +1 reviewed p.G344E 1.000 255 0.4% 385 61% 72 51.3% probably_damaging(0.999) deleterious(0) deleterious(0.935) HMMPfam_Cpn60_TCP1,superfamily_GroEL equatorial domain-like,superfamily_GroEL apical domain-like,superfamily_GroEL-intermediate domain like PRKAB1 5564 genome.wustl.edu 37 12 120110179 120110179 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_006253.4 +1 reviewed p.R78P 1.000 118 0% 93 41.9% 0 - possibly_damaging(0.628) tolerated(0.26) neutral(0.253) NULL LRRC43 254050 genome.wustl.edu 37 12 122670797 122670797 + Missense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001098519.1 +1 validated p.A158T 1.000 45 0% 33 30.3% 0 - probably_damaging(0.98) tolerated(0.13) deleterious(0.676) superfamily_Outer arm dynein light chain 1 DNAJC15 29103 genome.wustl.edu 37 13 43643082 43643082 + Silent SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_013238.2 +1 validated p.R59 0.962 92 0% 80 38.8% 51 3.9% - - - NULL LIPC 3990 genome.wustl.edu 37 15 58840773 58840773 + Splice_Site SNP T T A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000236.2 +1 reviewed e6+2 1.000 21 0% 21 47.6% 0 - - - - - GRIN2A 2903 genome.wustl.edu 37 16 10274194 10274194 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000833.3 -1 reviewed p.A25 0.992 46 0% 34 61.8% 0 - - - - superfamily_Periplasmic binding protein-like I MYH11 4629 genome.wustl.edu 37 16 15813109 15813109 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001040114.1 -1 reviewed p.L1720 1.000 110 0% 116 50% 1 0% - - - HMMPfam_Myosin_tail_1 GTF3C1 2975 genome.wustl.edu 37 16 27503657 27503657 + Splice_Site SNP A A T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001520.3 -1 validated e19+2 1.000 80 0% 98 45.9% 1 100% - - - - HYDIN 54768 genome.wustl.edu 37 16 71098642 71098642 + Missense_Mutation SNP T T A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_032821.2 -1 validated p.D726V 0.126 80 0% 44 90.9% 0 - probably_damaging(0.999) tolerated(0.07) deleterious(0.809) NULL ZFHX3 463 genome.wustl.edu 37 16 72821683 72821683 + Nonsense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_006885.3 -1 reviewed p.Q3498* 1.000 49 0% 21 81% 1 100% - - - NULL TP53 7157 genome.wustl.edu 37 17 7578235 7578235 + Missense_Mutation SNP T T C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_000546.4 -1 reviewed p.Y205C 0.989 211 0% 109 87.2% 5 100% probably_damaging(0.999) deleterious(0) deleterious(0.935) superfamily_p53-like transcription factors,HMMPfam_P53 ACSF2 80221 genome.wustl.edu 37 17 48539624 48539624 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_025149.4 +1 validated p.E196G 1.000 86 0% 37 75.7% 2 50% probably_damaging(1) deleterious(0.03) deleterious(0.865) HMMPfam_AMP-binding,superfamily_SSF56801 TEX14 56155 genome.wustl.edu 37 17 56676936 56676936 + Missense_Mutation SNP C C G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_198393.2 -1 reviewed p.E590D 0.011 127 0.8% 77 74% 0 - benign(0.15) deleterious(0.01) neutral(0.419) NULL ZNF431 170959 genome.wustl.edu 37 19 21365601 21365601 + Silent SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_133473.2 +1 validated p.N165 0.002 275 0% 248 33.1% 0 - - - - NULL ZNF99 7652 genome.wustl.edu 37 19 22940411 22940411 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001080409.1 -1 provisional p.G676V 0.043 296 0.3% 306 34.6% 0 - probably_damaging(0.998) deleterious(0) deleterious(0.919) HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667 LTBP4 8425 genome.wustl.edu 37 19 41118087 41118087 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000308370 +1 known p.G830A 1.000 25 0% 22 86.4% 4 25% probably_damaging(0.992) deleterious(0.02) deleterious(0.831) HMMSmart_EGF_CA,superfamily_Grow_fac_recept,HMMPfam_EGF_CA ARHGAP35 2909 genome.wustl.edu 37 19 47423229 47423229 + Nonsense_Mutation SNP C C T novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_004491.4 +1 reviewed p.R433* 0.723 193 0% 174 92.5% 0 - - - - HMMSmart_SM00441 PCSK2 5126 genome.wustl.edu 37 20 17434477 17434477 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_002594.2 +1 reviewed p.M326V 1.000 51 0% 66 42.4% 0 - possibly_damaging(0.889) deleterious(0) deleterious(0.794) HMMPfam_Peptidase_S8,superfamily_Subtilisin-like ENSG00000211459 0 genome.wustl.edu 37 MT 1199 1199 + RNA SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000389680 +1 known NULL NULL 65 1.5% 48 20.8% 2885 23.6% - - - - ENSG00000210140 0 genome.wustl.edu 37 MT 5791 5791 + RNA SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000387405 -1 novel NULL NULL 78 0% 48 97.9% 2095 95.3% - - - - ENSG00000210151 0 genome.wustl.edu 37 MT 7453 7453 + RNA SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e ENST00000387416 -1 novel NULL NULL 94 0% 64 100% 7928 96.1% - - - - HEPH 9843 genome.wustl.edu 37 X 65409629 65409629 + Missense_Mutation SNP C C A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_138737.3 +1 reviewed p.H307Q 1.000 130 0% 180 45% 0 - probably_damaging(1) deleterious(0) deleterious(0.945) HMMPfam_Cu-oxidase,superfamily_Cupredoxins AWAT2 158835 genome.wustl.edu 37 X 69263462 69263462 + Missense_Mutation SNP G G A novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001002254.1 -1 reviewed p.A113V 0.047 56 0% 50 56% 0 - benign(0.103) tolerated(0.49) neutral(0.019) HMMPfam_DAGAT TEX11 56159 genome.wustl.edu 37 X 69945133 69945133 + Missense_Mutation SNP A A G novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_001003811.1 -1 reviewed p.S317P 0.000 205 0% 249 41.8% 0 - benign(0.278) tolerated(0.35) neutral(0.051) HMMPfam_SPO22,superfamily_TPR-like MAGT1 84061 genome.wustl.edu 37 X 77112976 77112980 + Frame_Shift_Del DEL GAGCT GAGCT - novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 GAGCT GAGCT Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_032121.5 -1 reviewed p.A168fs 1.000:1.000:1.000:1.000:0.989 - - - - - - - - - HMMPfam_OST3_OST6,superfamily_Thioredoxin-like FATE1 89885 genome.wustl.edu 37 X 150885858 150885858 + Missense_Mutation SNP G G C novel TCGA-AP-A05A-01A-11W-A027-09 TCGA-AP-A05A-10A-01W-A027-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx 9e577e65-25e4-4d44-9900-d173f3a85e77 30a2164f-ac5a-478e-ae39-d0ef0b3f004e NM_033085.2 +1 reviewed p.R74P 0.000 190 0.5% 277 30.7% 0 - probably_damaging(0.998) tolerated(0.11) deleterious(0.746) NULL