Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
CHIAP2	0	genome.wustl.edu	37	1	111824840	111824840	+	RNA	SNP	T	T	A			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	1	111824840	111824840	T	A	SNP	CHIAP2	ENST00000369743	human	ensembl	74_37	1	known	rna	NULL	NULL	0.014	0	0	0	no_errors	0	0	0	14	0	0	14	4	21.05	151	1	0.65	181	8	4.19
NLRC4	0	genome.wustl.edu	37	2	32477618	32477618	+	Missense_Mutation	SNP	C	C	A			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	2	32477618	32477618	C	A	SNP	NLRC4	ENST00000360906	human	ensembl	74_37	-1	known	missense	c.132	p.E44D	0.468	pfam_CARD,superfamily_DEATH-like_dom,pfscan_CARD	pfam_CARD,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,pfscan_NACHT_NTPase,pfscan_CARD	0	no_errors	0	0	0	52	0	0	44	23	34.33	192	0	0.00	121	103	45.98
PKP4	0	genome.wustl.edu	37	2	159530414	159530414	+	Missense_Mutation	SNP	A	A	G			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	2	159530414	159530414	A	G	SNP	PKP4	ENST00000389759	human	ensembl	74_37	1	known	missense	c.3029	p.H1010R	1	NULL	pfam_Armadillo,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	0	no_errors	0	0	0	49	0	0	32	4	11.11	213	0	0.00	269	58	17.74
ZDHHC11B	0	genome.wustl.edu	37	5	751357	751357	+	Silent	SNP	A	A	G			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	5	751357	751357	A	G	SNP	ZDHHC11B	ENST00000382776	human	ensembl	74_37	-1	known	silent	c.519	p.T173	0.001	pfam_Znf_DHHC_palmitoyltrfase,pfscan_Znf_DHHC_palmitoyltrfase	pfam_Znf_DHHC_palmitoyltrfase,pfscan_Znf_DHHC_palmitoyltrfase	0	no_errors	0	0	0	88	0	0	58	18	23.68	8	0	0.00	16	5	23.81
SLC25A46	0	genome.wustl.edu	37	5	110074966	110074966	+	Missense_Mutation	SNP	T	T	G			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	5	110074966	110074966	T	G	SNP	SLC25A46	ENST00000355943	human	ensembl	74_37	1	known	missense	c.146	p.I49S	1	NULL	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier	0	no_errors	0	0	0	84	0	0	52	46	46.94	72	0	0.00	47	33	40.74
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	354	0	0	225	149	39.84	110	0	0.00	69	70	50.36
TSPYL5	0	genome.wustl.edu	37	8	98289254	98289254	+	Silent	SNP	T	T	A			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	8	98289254	98289254	T	A	SNP	TSPYL5	ENST00000322128	human	ensembl	74_37	-1	known	silent	c.819	p.V273	0	pfam_NAP_family	pfam_NAP_family	0	no_errors	0	0	0	32	0	0	20	7	25.93	171	0	0.00	223	44	16.48
MYOF	0	genome.wustl.edu	37	10	95097618	95097618	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	10	95097618	95097618	T	C	SNP	MYOF	ENST00000359263	human	ensembl	74_37	-1	known	missense	c.4391	p.H1464R	0.892	NULL	pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,pfam_Ferlin_A-domain,superfamily_C2_dom,smart_C2_dom,smart_Peroxin/Ferlin,pfscan_C2_dom	0	no_errors	0	0	0	77	0	0	86	8	8.51	255	0	0.00	297	22	6.90
SLC18A2	0	genome.wustl.edu	37	10	119013570	119013570	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	10	119013570	119013570	T	C	SNP	SLC18A2	ENST00000298472	human	ensembl	74_37	1	known	missense	c.535	p.S179P	1	pfam_MFS,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	0	no_errors	0	0	0	24	0	0	17	2	10.53	92	0	0.00	128	10	7.25
KRAS	0	genome.wustl.edu	37	12	25398284	25398284	+	Missense_Mutation	SNP	C	C	T			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	12	25398284	25398284	C	T	SNP	KRAS	ENST00000256078	human	ensembl	74_37	-1	known	missense	c.35	p.G12D	1	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	pfam_Small_GTPase,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_EF_GTP-bd_dom,superfamily_P-loop_NTPase,smart_Small_GTPase_Ras,smart_Small_GTPase_Rab_type,smart_Small_GTPase_Rho,smart_Ran_GTPase,prints_Small_GTPase,tigrfam_Small_GTP-bd_dom	0	no_errors	rs121913529	C->A,G,T	0	69	0	0	32	24	42.86	180	0	0.00	133	104	43.88
SEC23A	0	genome.wustl.edu	37	14	39512039	39512039	+	Missense_Mutation	SNP	C	C	G			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	14	39512039	39512039	C	G	SNP	SEC23A	ENST00000307712	human	ensembl	74_37	-1	known	missense	c.1937	p.R646P	1	pfam_Gelsolin_dom	pfam_Sec23/24_trunk_dom,pfam_Sec23/24_helical_dom,pfam_Sec23_24_beta_S,pfam_Znf_Sec23_Sec24,pfam_Gelsolin_dom,superfamily_Sec23/24_helical_dom,superfamily_Znf_Sec23_Sec24	0	no_errors	0	0	0	192	0	0	109	84	43.52	217	0	0.00	119	115	49.15
CD226	0	genome.wustl.edu	37	18	67563024	67563024	+	Missense_Mutation	SNP	C	C	G			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	18	67563024	67563024	C	G	SNP	CD226	ENST00000280200	human	ensembl	74_37	-1	known	missense	c.640	p.V214L	0	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	0	no_errors	0	0	0	42	0	0	24	22	45.83	116	0	0.00	98	61	38.36
FCGBP	0	genome.wustl.edu	37	19	40366440	40366440	+	Silent	SNP	G	G	T			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	19	40366440	40366440	G	T	SNP	FCGBP	ENST00000221347	human	ensembl	74_37	-1	known	silent	c.13794	p.R4598	0.995	pfam_VWF_type-D,smart_VWF_type-D	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,smart_Fol_N,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_EG-like_dom,smart_VWF_C,smart_VWC_out	0	no_errors	0	0	0	92	0	0	132	20	13.16	132	2	1.49	152	38	19.90
OPRL1	0	genome.wustl.edu	37	20	62730015	62730015	+	Missense_Mutation	SNP	T	T	C			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	20	62730015	62730015	T	C	SNP	OPRL1	ENST00000336866	human	ensembl	74_37	1	known	missense	c.976	p.F326L	1	pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,prints_GPCR_Rhodpsn,prints_Opioid_rcpt,prints_Somatstn_rcpt,prints_NPY_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfam_7TM_GPCR_serpentine_rcpt_Srv,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfscan_GPCR_Rhodpsn_7TM,prints_X_opioid_rcpt,prints_GPCR_Rhodpsn,prints_Opioid_rcpt,prints_Somatstn_rcpt,prints_Neuropept_B/W_rcpt,prints_NPY_rcpt	0	no_errors	0	0	0	21	0	0	6	10	62.5	69	0	0.00	52	35	40.23
DNER	0	genome.wustl.edu	37	2	230456533	230456535	+	In_Frame_Del	DEL	GCT	GCT	-			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	GCT	GCT	GCT	-	GCT	GCT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	2	230456533	230456535	GCT	0	DEL	DNER	ENST00000341772	human	ensembl	74_37	-1	known	in_frame_del	c.348_346	p.S116in_frame_del	0.003:0.004:0.006	pfam_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pfam_EG-like_dom,pfam_EGF_extracell,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	0	no_errors	0	0	0	28	0	0	35	3	7.89	51	0	0.00	53	3	5.36
UBA6	0	genome.wustl.edu	37	4	68488877	68488877	+	Frame_Shift_Del	DEL	G	G	-			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	4	68488877	68488877	G	0	DEL	UBA6	ENST00000322244	human	ensembl	74_37	-1	known	frame_shift_del	c.2904	p.L969fs	0.959	pfam_Ub-activating_enz_e1_C,tigrfam_UBQ-activ_enz_E1	pfam_ThiF_NAD_FAD-bd,pfam_Ub-activating_enz_e1_C,pfam_UBact_repeat,pfam_Ubiquitin-activating_enzyme,superfamily_Molybdenum_cofac_synth_MoeB,prints_UBQ/SUMO-activ_enz_E1-like,tigrfam_UBQ-activ_enz_E1	0	no_errors	0	0	0	79	0	0	72	14	16.28	264	0	0.00	321	33	9.32
RAI1	0	genome.wustl.edu	37	17	17697094	17697096	+	In_Frame_Del	DEL	CAG	CAG	-			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	CAG	CAG	CAG	-	CAG	CAG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	17	17697094	17697096	CAG	0	DEL	RAI1	ENST00000353383	human	ensembl	74_37	1	known	in_frame_del	c.832_834	p.Q281in_frame_del	0.831:0.157:0.050	NULL	smart_Znf_PHD	0	no_errors	rs113303801	CCAG->C	0	42	0	0	42	6	12.5	18	0	0.00	23	7	23.33
PHF2	0	genome.wustl.edu	37	9	96435987	96435987	+	Silent	SNP	C	C	T			TCGA-ZB-A96H-01A-11D-A428-09	TCGA-ZB-A96H-10A-01D-A42B-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	573c0a47-4c4e-4952-b5c7-8d1c1eecfe04	eabeb6bb-4935-4514-8c57-330b48d8634e	9	96435987	96435987	C	T	SNP	PHF2	ENST00000359246	human	ensembl	74_37	1	known	silent	c.2469	p.S823	1	NULL	pfam_JmjC_dom,pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,smart_JmjC_dom,pfscan_JmjC_dom,pfscan_Znf_PHD-finger	0	no_errors	0	0	0	44	0	0	31	4	11.43	2	0	0.00	7	0	0.00