Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	rsID	rsID_ref_var_alleles	CAF	normal_ref_reads	normal_var_reads	normal_vaf	tumor_ref_reads	tumor_var_reads	tumor_vaf	normal_ref_reads_val	normal_var_reads_val	normal_vaf_val	tumor_ref_reads_val	tumor_var_reads_val	tumor_vaf_val
ZNF638	0	genome.wustl.edu	37	2	71595630	71595630	+	Missense_Mutation	SNP	A	A	G			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	2	71595630	71595630	A	G	SNP	ZNF638	ENST00000264447	human	ensembl	74_37	1	known	missense	c.2114	p.D705G	1	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	pfam_RRM_dom,smart_Znf_U1,smart_Znf_C2H2-like,smart_RRM_dom,pfscan_Znf_C2H2_matrin,pfscan_RRM_dom	0	no_errors	0	0	0	98	0	0	76	13	14.61	255	0	0.00	162	53	24.65
MARCH7	0	genome.wustl.edu	37	2	160615812	160615812	+	Missense_Mutation	SNP	T	T	G			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	2	160615812	160615812	T	G	SNP	MARCH7	ENST00000259050	human	ensembl	74_37	1	known	missense	c.1859	p.I620S	1	NULL	pfam_Znf_C3HC4_RING-type,smart_Znf_RING-CH	0	no_errors	0	0	0	67	0	0	62	11	15.07	276	0	0.00	171	50	22.62
ATG9A	0	genome.wustl.edu	37	2	220091611	220091611	+	Nonsense_Mutation	SNP	G	G	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	2	220091611	220091611	G	T	SNP	ATG9A	ENST00000412355	human	ensembl	74_37	-1	known	nonsense	c.194	p.S65*	0.595	NULL	NULL	0	no_errors	0	0	0	94	0	0	48	22	31.43	284	0	0.00	159	58	26.73
PARP15	0	genome.wustl.edu	37	3	122351025	122351025	+	Missense_Mutation	SNP	G	G	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	3	122351025	122351025	G	T	SNP	PARP15	ENST00000464300	human	ensembl	74_37	1	known	missense	c.1531	p.D511Y	0	pfam_Poly(ADP-ribose)pol_cat_dom,pfscan_Poly(ADP-ribose)pol_cat_dom	pfam_Macro_dom,pfam_Poly(ADP-ribose)pol_cat_dom,smart_Macro_dom,pfscan_Macro_dom,pfscan_Poly(ADP-ribose)pol_cat_dom	0	no_errors	0	0	0	33	0	0	31	5	13.89	193	0	0.00	129	43	24.71
MMRN1	0	genome.wustl.edu	37	4	90856011	90856011	+	Nonsense_Mutation	SNP	C	C	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	4	90856011	90856011	C	T	SNP	MMRN1	ENST00000264790	human	ensembl	74_37	1	known	nonsense	c.1180	p.Q394*	1	NULL	pfam_C1q,pfam_EMI_domain,pfam_EG-like_dom,superfamily_Tumour_necrosis_fac-like_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_C1q,prints_C1q,pfscan_C1q,pfscan_EG-like_dom,pfscan_EMI_domain	0	no_errors	0	0	0	83	0	0	55	8	12.7	183	0	0.00	137	26	15.95
ATG5	0	genome.wustl.edu	37	6	106634402	106634402	+	RNA	SNP	A	A	C			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	6	106634402	106634402	A	C	SNP	ATG5	ENST00000475645	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	0	0	0	no_errors	0	0	0	20	0	0	24	6	20	276	0	0.00	188	59	23.89
WBSCR17	0	genome.wustl.edu	37	7	70880948	70880948	+	Missense_Mutation	SNP	G	G	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	7	70880948	70880948	G	T	SNP	WBSCR17	ENST00000333538	human	ensembl	74_37	1	known	missense	c.663	p.Q221H	0.998	pfam_Glyco_trans_2	pfam_Glyco_trans_2,pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	0	no_errors	0	0	0	33	0	0	23	8	25.81	207	0	0.00	127	26	16.99
GTF2I	0	genome.wustl.edu	37	7	74146970	74146970	+	Missense_Mutation	SNP	T	T	A			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	7	74146970	74146970	T	A	SNP	GTF2I	ENST00000324896	human	ensembl	74_37	1	known	missense	c.1271	p.L424H	1	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	pfam_GTF2I,superfamily_GTF2I,pirsf_TF_II-I,pfscan_GTF2I	0	no_errors	0	0	0	292	0	0	244	78	24.22	133	0	0.00	89	24	21.24
ZNF7	0	genome.wustl.edu	37	8	146063439	146063439	+	Silent	SNP	G	G	A			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	8	146063439	146063439	G	A	SNP	ZNF7	ENST00000528130	human	ensembl	74_37	1	putative	silent	c.294	p.P98	0	NULL	pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,pfscan_Krueppel-associated_box	0	no_errors	0	0	0	90	0	0	59	12	16.9	186	2	1.06	94	32	25.40
PCSK5	0	genome.wustl.edu	37	9	78953202	78953202	+	Missense_Mutation	SNP	G	G	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	9	78953202	78953202	G	T	SNP	PCSK5	ENST00000545128	human	ensembl	74_37	1	known	missense	c.4724	p.G1575V	0.001	superfamily_Growth_fac_rcpt_N_dom,smart_Furin_repeat	pfam_Peptidase_S8/S53_dom,pfam_PrprotnconvertsP,superfamily_Peptidase_S8/S53_dom,superfamily_Galactose-bd-like,superfamily_Growth_fac_rcpt_N_dom,superfamily_Prot_inh_propept,smart_Furin_repeat,smart_EG-like_dom,prints_Peptidase_S8_subtilisin-rel	0	no_errors	rs535037527	G->T	0.9998,0.0001997	40	0	0	30	9	22.5	121	0	0.00	58	17	22.67
ALOX5	0	genome.wustl.edu	37	10	45939679	45939679	+	Missense_Mutation	SNP	G	G	A			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	10	45939679	45939679	G	A	SNP	ALOX5	ENST00000374391	human	ensembl	74_37	1	known	missense	c.1790	p.R597H	1	pfam_LipOase_C,superfamily_LipOase_C,prints_LipOase_mml	pfam_LipOase_C,pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,prints_LipOase_mml,prints_LipOase_C,pfscan_PLAT/LH2_dom	0	no_errors	0	0	0	119	0	0	86	25	22.52	45	0	0.00	25	15	37.50
ABTB2	0	genome.wustl.edu	37	11	34378463	34378463	+	Missense_Mutation	SNP	A	A	G			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	11	34378463	34378463	A	G	SNP	ABTB2	ENST00000435224	human	ensembl	74_37	-1	known	missense	c.668	p.I223T	1	superfamily_Histone-fold	pfam_BTB_POZ,pfam_Ankyrin_rpt,superfamily_Histone-fold,superfamily_BTB/POZ_fold,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_BTB/POZ-like,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_BTB/POZ-like	0	no_errors	0	0	0	66	1	1.49	37	21	36.21	48	0	0.00	46	11	19.30
SYT7	0	genome.wustl.edu	37	11	61291930	61291930	+	Missense_Mutation	SNP	C	C	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	11	61291930	61291930	C	T	SNP	SYT7	ENST00000263846	human	ensembl	74_37	-1	known	missense	c.697	p.D233N	1	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom,prints_Synaptotagmin,prints_C2_dom	0	no_errors	0	0	0	55	0	0	43	16	27.12	181	0	0.00	102	39	27.66
OR6C65	0	genome.wustl.edu	37	12	55794550	55794550	+	Silent	SNP	C	C	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	12	55794550	55794550	C	T	SNP	OR6C65	ENST00000379665	human	ensembl	74_37	1	known	silent	c.238	p.L80	0.004	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,prints_Olfact_rcpt,prints_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	0	no_errors	0	0	0	34	0	0	31	13	29.55	259	0	0.00	207	48	18.82
NBEA	0	genome.wustl.edu	37	13	35738643	35738643	+	Silent	SNP	A	A	C			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	13	35738643	35738643	A	C	SNP	NBEA	ENST00000310336	human	ensembl	74_37	1	known	silent	c.4230	p.P1410	0.981	NULL	pfam_BEACH_dom,pfam_DUF1088,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_ConA-like_lec_gl_sf,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat_dom	0	no_errors	0	0	0	38	0	0	47	9	16.07	239	1	0.41	174	61	25.96
RSU1	0	genome.wustl.edu	37	10	16859406	16859406	+	RNA	DEL	G	G	-			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	10	16859406	16859406	G	0	DEL	RSU1	ENST00000377911	human	ensembl	74_37	-1	known	rna	NULL	NULL	0	0	0	0	no_errors	0	0	0	42	0	0	50	7	12.28	51	0	0.00	47	17	26.56
PPFIA3	0	genome.wustl.edu	37	19	49641538	49641539	+	Frame_Shift_Ins	INS	-	-	A			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	-	-	-	A	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	19	49641538	49641539	0	A	INS	PPFIA3	ENST00000334186	human	ensembl	74_37	1	known	frame_shift_ins	c.1930_1931	p.D644fs	0.999:0.852	NULL	pfam_SAM_2,pfam_SAM_type1,superfamily_SAM/pointed,smart_SAM,pfscan_SAM	0	no_errors	0	0	0	188	0	0	90	32	26.23	95	0	0.00	71	14	16.47
GOLGA6L7P	0	genome.wustl.edu	37	15	29090308	29090308	+	RNA	SNP	A	A	C			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	15	29090308	29090308	A	C	SNP	GOLGA6L7P	ENST00000569815	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.017	0	0	0	no_errors	rs2021013	A->C	0	9	0	0	2	2	40	0	0	0.00	0	0	0.00
KIR3DL2	0	genome.wustl.edu	37	19	55363631	55363631	+	Silent	SNP	C	C	T			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	19	55363631	55363631	C	T	SNP	KIR3DL2	ENST00000326321	human	ensembl	74_37	1	known	silent	c.249	p.G83	0.029	pfam_Immunoglobulin,smart_Ig_sub	pfam_Immunoglobulin,smart_Ig_sub	0	no_errors	0	0	0	21	0	0	21	3	12.5	18	0	0.00	9	0	0.00
ENSG00000216020	0	genome.wustl.edu	37	3	191693763	191693764	+	RNA	INS	-	-	GC			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	3	191693763	191693764	0	GC	INS	ENSG00000216020	ENST00000401201	human	ensembl	74_37	1	novel	rna	NULL	NULL	0.013:0.015	0	0	0	no_errors	rs142374799	T->TGC	0	13	0	0	5	4	44.44	0	0	0.00	0	0	0.00
MTCH1	0	genome.wustl.edu	37	6	36945416	36945416	+	Frame_Shift_Del	DEL	G	G	-			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	6	36945416	36945416	G	0	DEL	MTCH1	ENST00000373627	human	ensembl	74_37	-1	known	frame_shift_del	c.643	p.L215fs	1	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier	pfam_Mitochondrial_sb/sol_carrier,superfamily_Mt_carrier_dom,pfscan_Mitochondrial_sb/sol_carrier	0	no_errors	0	0	0	32	0	0	18	3	14.29	10	0	0.00	9	0	0.00
NACAD	0	genome.wustl.edu	37	7	45123654	45123655	+	Frame_Shift_Ins	INS	-	-	C			TCGA-5K-AAAP-01A-11D-A423-09	TCGA-5K-AAAP-10A-01D-A426-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e7fccb59-0f2a-4e56-a368-b4d34c474334	6c0eb94a-494b-4eb9-9a76-b0459685bd21	7	45123654	45123655	0	C	INS	NACAD	ENST00000490531	human	ensembl	74_37	-1	known	frame_shift_ins	c.2125_2124	p.Q708fs	0.000:0.000	NULL	pfam_Nas_poly-pep-assoc_cplx_dom,pfscan_Nas_poly-pep-assoc_cplx_dom	0	no_errors	0	0	0	21	0	0	26	4	13.33	0	0	0.00	0	0	0.00