Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CEP128	145508	broad.mit.edu	37	14	81371163	81371163	+	Missense_Mutation	SNP	C	C	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr14:81371163C>A	ENST00000555265.1	-	6	849	c.474G>T	c.(472-474)atG>atT	p.M158I	CEP128_ENST00000281129.3_Missense_Mutation_p.M158I|CEP128_ENST00000327841.2_Missense_Mutation_p.M98I|CEP128_ENST00000216517.6_Missense_Mutation_p.M158I			Q6ZU80	CE128_HUMAN	centrosomal protein 128kDa	158						centriole|spindle pole				NS(1)|breast(3)|central_nervous_system(2)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(7)|lung(22)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	51						GTACCTGAGTCATATCATCAG	0.378000													3	50					1	1	1	1	0
PCSK4	54760	broad.mit.edu	37	19	1490315	1490315	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr19:1490315G>A	ENST00000300954.5	-	1	92	c.31C>T	c.(31-33)Cgc>Tgc	p.R11C	PCSK4_ENST00000587784.1_Intron	NM_017573.3	NP_060043.2	Q6UW60	PCSK4_HUMAN	proprotein convertase subtilisin/kexin type 4	11					proteolysis	integral to membrane	serine-type endopeptidase activity			cervix(2)|endometrium(2)|kidney(1)|lung(6)|ovary(2)|skin(1)|upper_aerodigestive_tract(1)	15		Acute lymphoblastic leukemia(61;3.02e-13)|all_hematologic(61;4.32e-09)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		AAGACCAGGCGCAGCCACAGC	0.751000													2	1					0	0	1	0	0
PLXNC1	10154	broad.mit.edu	37	12	94641772	94641772	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr12:94641772G>A	ENST00000258526.4	+	13	2731	c.2482G>A	c.(2482-2484)Gta>Ata	p.V828I		NM_005761.2	NP_005752.1	O60486	PLXC1_HUMAN	plexin C1	828					axon guidance|cell adhesion	integral to membrane|intracellular|plasma membrane	receptor activity|receptor binding			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(4)|kidney(4)|large_intestine(12)|lung(30)|ovary(2)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	64						GAAGCTGAGAGTACAAGACAC	0.507000													3	38					0	0	1	0	0
CLTCL1	8218	broad.mit.edu	37	22	19183842	19183842	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr22:19183842G>A	ENST00000263200.10	-	26	4198	c.4126C>T	c.(4126-4128)Ctc>Ttc	p.L1376F	CLTCL1_ENST00000427926.1_Missense_Mutation_p.L1376F|CLTCL1_ENST00000353891.5_Missense_Mutation_p.L1376F|CLTCL1_ENST00000442042.2_5'UTR	NM_007098.3	NP_009029.3	P53675	CLH2_HUMAN	clathrin, heavy chain-like 1	1376	Heavy chain arm.|Involved in binding clathrin light chain (By similarity).|Proximal segment.				anatomical structure morphogenesis|intracellular protein transport|mitosis|positive regulation of glucose import|receptor-mediated endocytosis	clathrin coat of coated pit|clathrin coat of trans-Golgi network vesicle|spindle|trans-Golgi network	protein binding|signal transducer activity|structural molecule activity			breast(2)|central_nervous_system(3)|cervix(2)|endometrium(9)|kidney(3)|large_intestine(11)|lung(9)|ovary(5)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	49	Colorectal(54;0.0993)					ATCATGGTGAGCACAGCATTG	0.567000			T	?	ALCL								3	46					0	0	1	0	0
LETM1	3954	broad.mit.edu	37	4	1843468	1843468	+	Missense_Mutation	SNP	C	C	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr4:1843468C>A	ENST00000302787.2	-	3	496	c.200G>T	c.(199-201)gGc>gTc	p.G67V		NM_012318.2	NP_036450.1	O95202	LETM1_HUMAN	leucine zipper-EF-hand containing transmembrane protein 1	67					cristae formation	integral to membrane|mitochondrial inner membrane	calcium ion binding|protein binding			breast(3)|central_nervous_system(2)|large_intestine(3)|lung(3)|prostate(1)|urinary_tract(1)	13			all cancers(2;0.00756)|OV - Ovarian serous cystadenocarcinoma(23;0.00989)|Epithelial(3;0.0141)			GAGGTGATCGCCTCTGGAGGA	0.552000													7	26					5.18039e-06	5.82794e-06	1	1	0
AC024560.3	0	broad.mit.edu	37	3	197348674	197348674	+	RNA	SNP	A	A	G	rs144273946	by1000genomes	TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr3:197348674A>G	ENST00000418868.1	-	0	585					NR_003266.2																						GGCTCTGTCCACCAAATGCAC	0.478000													4	82					0	0	1	0	0
ZNF225	7768	broad.mit.edu	37	19	44635831	44635831	+	Missense_Mutation	SNP	A	A	G			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr19:44635831A>G	ENST00000262894.6	+	5	1344	c.1064A>G	c.(1063-1065)tAt>tGt	p.Y355C	ZNF225_ENST00000592780.1_3'UTR|ZNF225_ENST00000590612.1_Missense_Mutation_p.Y355C	NM_013362.2	NP_037494.2	Q9UK10	ZN225_HUMAN	zinc finger protein 225	355					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			NS(1)|breast(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(7)|skin(1)|stomach(1)	16		Prostate(69;0.0352)|all_neural(266;0.202)				CGCTTCATTTATAGGCAAGAT	0.423000													17	29					0	0	1	0	0
NRAS	4893	broad.mit.edu	37	1	115256529	115256529	+	Missense_Mutation	SNP	T	T	C	rs11554290		TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr1:115256529T>C	ENST00000369535.4	-	3	435	c.182A>G	c.(181-183)cAa>cGa	p.Q61R		NM_002524.4	NP_002515.1	P01111	RASN_HUMAN	neuroblastoma RAS viral (v-ras) oncogene homolog	61			Q -> K (in neuroblastoma cell).|Q -> R (in lung carcinoma cell and melanoma; dbSNP:rs11554290).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	Golgi membrane|plasma membrane	GTP binding|GTPase activity	p.Q61R(817)|p.Q61L(175)|p.Q61P(23)|p.Q61K(1)		NS(134)|adrenal_gland(9)|autonomic_ganglia(9)|biliary_tract(6)|bone(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(11)|eye(3)|haematopoietic_and_lymphoid_tissue(1115)|kidney(3)|large_intestine(105)|liver(10)|lung(42)|meninges(2)|ovary(7)|pancreas(5)|prostate(8)|skin(1144)|soft_tissue(37)|stomach(5)|testis(8)|thyroid(359)|upper_aerodigestive_tract(28)|urinary_tract(13)	3085	all_epithelial(7;5.11e-05)|all_lung(7;0.000179)|Lung NSC(6;0.00195)|Lung SC(450;0.211)	all_cancers(81;4.64e-07)|all_epithelial(167;4.2e-07)|all_lung(203;9.97e-06)|Lung NSC(69;1.74e-05)		Lung(183;0.0234)|Colorectal(144;0.0686)|COAD - Colon adenocarcinoma(174;0.111)|all cancers(265;0.112)|Epithelial(280;0.124)|LUSC - Lung squamous cell carcinoma(189;0.133)		GTACTCTTCTTGTCCAGCTGT	0.458000	Q61L(C3A_LIVER)|Q61L(HEPG2_LIVER)|Q61L(HL60_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(IPC298_SKIN)|Q61L(KMS21BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(MELJUSO_SKIN)|Q61L(MHHES1_BONE)|Q61L(MOLP8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61L(OCIAML3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61P(TF1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(HT1197_URINARY_TRACT)|Q61R(KMS27_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|Q61R(KU1919_URINARY_TRACT)|Q61R(NCIH2347_LUNG)|Q61R(ONS76_CENTRAL_NERVOUS_SYSTEM)|Q61R(SKMEL2_SKIN)|Q61R(SW1271_LUNG)|Q61R(TT2609C02_THYROID)	50	Mis		"""melanoma, MM, AML, thyroid"""				Noonan syndrome	TSP Lung(23;0.16)|Multiple Myeloma(1;<1E-6)			39	71					0	0	1	0	0
LPHN1	22859	broad.mit.edu	37	19	14267930	14267930	+	Silent	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr19:14267930G>A	ENST00000340736.6	-	16	3085	c.2788C>T	c.(2788-2790)Ctg>Ttg	p.L930L	CTB-55O6.12_ENST00000592086.1_RNA|LPHN1_ENST00000361434.3_Silent_p.L925L|CTB-55O6.12_ENST00000588387.1_RNA	NM_001008701.2	NP_001008701.1	O94910	LPHN1_HUMAN	latrophilin 1	930					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity|sugar binding			central_nervous_system(1)|cervix(2)|endometrium(6)|kidney(1)|large_intestine(3)|liver(1)|lung(10)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	32						AAATAGTGCAGCAGGCCGGCG	0.642000													3	30					0	0	1	0	0
ATP1A2	477	broad.mit.edu	37	1	160106465	160106465	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr1:160106465G>A	ENST00000361216.3	+	19	2758	c.2669G>A	c.(2668-2670)cGg>cAg	p.R890Q	ATP1A2_ENST00000392233.3_Missense_Mutation_p.R890Q|ATP1A2_ENST00000472488.1_3'UTR	NM_000702.3	NP_000693.1	P50993	AT1A2_HUMAN	ATPase, Na+/K+ transporting, alpha 2 polypeptide	890					ATP biosynthetic process		ATP binding|metal ion binding|sodium:potassium-exchanging ATPase activity			NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(13)|lung(30)|ovary(2)|skin(3)|upper_aerodigestive_tract(1)	69	all_cancers(52;1.11e-16)|all_hematologic(112;0.093)		BRCA - Breast invasive adenocarcinoma(70;0.111)|LUSC - Lung squamous cell carcinoma(543;0.246)			TGGGATGACCGGACCATGAAT	0.552000													3	61					0	0	1	0	0
OAS3	4940	broad.mit.edu	37	12	113403801	113403801	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr12:113403801G>A	ENST00000228928.7	+	12	2835	c.2656G>A	c.(2656-2658)Gac>Aac	p.D886N	RP1-71H24.1_ENST00000552784.1_RNA	NM_006187.2	NP_006178.2	Q9Y6K5	OAS3_HUMAN	2'-5'-oligoadenylate synthetase 3, 100kDa	886	OAS domain 3.				interferon-gamma-mediated signaling pathway|nucleobase, nucleoside, nucleotide and nucleic acid metabolic process|type I interferon-mediated signaling pathway	microsome	ATP binding|nucleotidyltransferase activity|RNA binding			breast(3)|central_nervous_system(2)|endometrium(2)|kidney(3)|large_intestine(8)|lung(6)|ovary(1)|skin(2)	27						CCAGAGTGTGGACTTTGATGT	0.582000													15	18					0	0	1	0	0
ENPEP	2028	broad.mit.edu	37	4	111398204	111398204	+	Missense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr4:111398204G>A	ENST00000265162.5	+	1	976	c.634G>A	c.(634-636)Gga>Aga	p.G212R		NM_001977.3	NP_001968.3	Q07075	AMPE_HUMAN	glutamyl aminopeptidase (aminopeptidase A)	212					cell migration|cell proliferation|cell-cell signaling|proteolysis	integral to plasma membrane	aminopeptidase activity|metalloexopeptidase activity|zinc ion binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(12)|lung(22)|ovary(1)|prostate(3)|skin(8)|upper_aerodigestive_tract(2)|urinary_tract(1)	54		Hepatocellular(203;0.217)		OV - Ovarian serous cystadenocarcinoma(123;0.0031)	L-Glutamic Acid(DB00142)	CACGGAGAACGGACAAGTCAA	0.453000													7	32					0	0	1	0	0
RANBP10	57610	broad.mit.edu	37	16	67762359	67762359	+	Missense_Mutation	SNP	T	T	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr16:67762359T>A	ENST00000317506.3	-	11	1523	c.1408A>T	c.(1408-1410)Atg>Ttg	p.M470L	RANBP10_ENST00000536251.1_Missense_Mutation_p.M241L|RANBP10_ENST00000448631.2_Missense_Mutation_p.M444L|RANBP10_ENST00000411657.2_Missense_Mutation_p.M383L|RANBP10_ENST00000602677.1_Missense_Mutation_p.M500L	NM_020850.1	NP_065901.1	Q6VN20	RBP10_HUMAN	RAN binding protein 10	470										endometrium(5)|kidney(2)|large_intestine(3)|lung(10)|ovary(2)|skin(1)	23		Acute lymphoblastic leukemia(13;4.34e-06)|all_hematologic(13;0.000643)|Ovarian(137;0.192)		OV - Ovarian serous cystadenocarcinoma(108;0.00522)|Epithelial(162;0.025)|all cancers(182;0.157)		CGTGTGGACATGCTTCCTAGC	0.582000													18	40					0	0	1	0	0
FRG2B	441581	broad.mit.edu	37	10	135440166	135440166	+	Silent	SNP	G	G	T			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr10:135440166G>T	ENST00000443774.1	-	1	130	c.81C>A	c.(79-81)atC>atA	p.I27I	FRG2B_ENST00000425520.1_Silent_p.I27I			Q96QU4	FRG2B_HUMAN	FSHD region gene 2 family, member B	27						nucleus				endometrium(2)|kidney(2)|lung(14)|ovary(1)|prostate(1)	20		all_cancers(35;7.01e-07)|all_epithelial(44;1.45e-05)|Lung NSC(174;0.027)|all_lung(145;0.0384)|all_neural(114;0.0726)|Glioma(114;0.172)|Melanoma(40;0.175)		OV - Ovarian serous cystadenocarcinoma(35;1.12e-06)|all cancers(32;1.43e-06)|Epithelial(32;1.71e-06)		CTGTAAAGGAGATCTGTTGGA	0.488000													8	66					0.0809354	0.0856963	1	1	0
KCNH7	90134	broad.mit.edu	37	2	163302758	163302758	+	Nonsense_Mutation	SNP	G	G	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr2:163302758G>A	ENST00000332142.5	-	7	1423	c.1324C>T	c.(1324-1326)Cga>Tga	p.R442*	KCNH7_ENST00000328032.4_Nonsense_Mutation_p.R435*	NM_033272.3	NP_150375.2	Q9NS40	KCNH7_HUMAN	potassium voltage-gated channel, subfamily H (eag-related), member 7	442					regulation of transcription, DNA-dependent	integral to membrane	protein binding|signal transducer activity	p.R442*(1)|p.R435*(1)		NS(1)|biliary_tract(1)|breast(4)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(22)|lung(53)|ovary(3)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(3)	108					Ibutilide(DB00308)	CCACATTCTCGTCTTTTCTGT	0.383000													15	16					0	0	1	0	0
ZNF878	729747	broad.mit.edu	37	19	12155673	12155673	+	Missense_Mutation	SNP	A	A	C			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr19:12155673A>C	ENST00000602107.1	-	5	683	c.684T>G	c.(682-684)agT>agG	p.S228R	CTD-2006C1.2_ENST00000591898.1_RNA|CTD-2006C1.2_ENST00000591838.1_RNA|CTD-2006C1.2_ENST00000476474.1_RNA|CTD-2006C1.10_ENST00000547473.1_Intron|ZNF878_ENST00000547628.1_Missense_Mutation_p.S181R			C9JN71	ZN878_HUMAN	zinc finger protein 878	181					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	nucleic acid binding|zinc ion binding			cervix(1)|endometrium(1)|kidney(1)|lung(4)|urinary_tract(1)	8						AACTGGGAAAACTGAATGCTT	0.403000													4	97					0	0	1	0	0
AC133680.1	0	broad.mit.edu	37	3	24870607	24870607	+	RNA	DEL	A	A	-			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr3:24870607delA	ENST00000455576.1	+	0	132																											cacagcggtgaaggcggcagg	0.657													2	4	---	---	---	---					
FBXW4	6468	broad.mit.edu	37	10	103454358	103454360	+	In_Frame_Del	DEL	CCT	CCT	-			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr10:103454358_103454360delCCT	ENST00000331272.7	-	1	656_658	c.38_40delAGG	c.(37-42)gcg>g	p.EA13del		NM_022039.3	NP_071322.1	P57775	FBXW4_HUMAN	F-box and WD repeat domain containing 4	13					ubiquitin-dependent protein catabolic process|Wnt receptor signaling pathway	ubiquitin ligase complex				breast(3)|endometrium(2)|large_intestine(4)|lung(4)|skin(1)|stomach(1)	15		Colorectal(252;0.123)		Epithelial(162;4.35e-08)|all cancers(201;1.92e-06)		TCCCGAGCCGcctcctcctcctc	0.754													2	4	---	---	---	---					
RP11-307C19.2	0	broad.mit.edu	37	15	77868660	77868662	+	RNA	DEL	GGA	GGA	-			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr15:77868660_77868662delGGA	ENST00000561123.1	+	0	577																											GCCTCATGCTggaggaggaggag	0.621													3	3	---	---	---	---					
MIR3648	0	broad.mit.edu	37	21	9825852	9825853	+	RNA	INS	-	-	A			TCGA-FY-A3NP-01A-11D-A21A-08	TCGA-FY-A3NP-10A-01D-A21A-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	d117c65a-9493-4628-9eb0-1450fed1fb4f	7e10e1f6-d078-4e0b-aa0a-4be138ac0a3a	g.chr21:9825852_9825853insA	ENST00000581792.1	+	0	21_22					NR_037421.1																						gcggcggtggtggggggagccg	0.837													8	91	---	---	---	---