Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ZFHX3	463	broad.mit.edu	37	16	72845826	72845826	+	Missense_Mutation	SNP	G	G	C			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr16:72845826G>C	uc002fck.3	-	5	4314	c.3641C>G	c.(3640-3642)gCt>gGt	p.A1214G	ZFHX3_uc002fcl.3_Missense_Mutation_p.A300G	NM_006885	NP_008816	Q15911	ZFHX3_HUMAN	Homo sapiens zinc finger homeobox 3 (ZFHX3), transcript variant A, mRNA.	1214					muscle organ development|negative regulation of myoblast differentiation|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-dependent|positive regulation of myoblast differentiation	transcription factor complex	enzyme binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|transcription regulatory region DNA binding|zinc ion binding			NS(3)|breast(7)|cervix(2)|endometrium(18)|haematopoietic_and_lymphoid_tissue(5)|kidney(8)|large_intestine(22)|liver(1)|lung(46)|ovary(5)|pancreas(1)|prostate(15)|skin(6)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(11)	153		Ovarian(137;0.13)				GATCTCCTCAGCTGTTTTTGG	0.542000													123	227					0	0	1	0	0
EIF3L	51386	broad.mit.edu	37	22	38251638	38251638	+	Silent	SNP	A	A	G			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr22:38251638A>G	uc003auf.3	+	3	438	c.360A>G	c.(358-360)ccA>ccG	p.P120P	EIF3L_uc011ann.2_Silent_p.P120P|EIF3L_uc003aug.3_Intron	NM_016091	NP_057175	Q9Y262	EIF3L_HUMAN	Homo sapiens eukaryotic translation initiation factor 3, subunit L (EIF3L), transcript variant 1, mRNA.	120						eukaryotic translation initiation factor 3 complex	protein binding|translation initiation factor activity			kidney(2)|large_intestine(3)|lung(4)|ovary(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	15						CCATTGCTCCACAGGTTGGCA	0.448000													10	29					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr7:140453136A>T	uc003vwc.4	-	14	1860	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333	NP_004324	P15056	BRAF_HUMAN	Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA.	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				29	63					0	0	1	0	0
OTUD4	54726	broad.mit.edu	37	4	146059006	146059006	+	Missense_Mutation	SNP	G	G	A			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr4:146059006G>A	uc003ika.4	-	20	2864	c.2726C>T	c.(2725-2727)aCt>aTt	p.T909I		NM_001102653	NP_001096123	Q01804	OTUD4_HUMAN	Homo sapiens OTU domain containing 4 (OTUD4), transcript variant 3, mRNA.	973							protein binding			breast(1)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|lung(10)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)	33	all_hematologic(180;0.151)					AACAGGCACAGTTTCTCTCTC	0.463000													4	160					0	0	1	0	0
VGLL3	389136	broad.mit.edu	37	3	87017837	87017837	+	Silent	SNP	T	T	C			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr3:87017837T>C	uc003dqn.3	-	2	1204	c.840A>G	c.(838-840)acA>acG	p.T280T		NM_016206	NP_057290	A8MV65	VGLL3_HUMAN	Homo sapiens vestigial like 3 (Drosophila) (VGLL3), mRNA.	280					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus				NS(1)|breast(1)|endometrium(4)|large_intestine(2)|lung(11)	19	all_cancers(8;0.109)|Lung SC(3;0.184)	Lung NSC(201;0.0777)		LUSC - Lung squamous cell carcinoma(29;0.00241)|Lung(72;0.00712)		GTTCTGTCTTTGTGATGTCAC	0.557000													9	29					0	0	1	0	0
MYH14	79784	broad.mit.edu	37	19	50812344	50812344	+	Missense_Mutation	SNP	G	G	A			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr19:50812344G>A	uc010enu.1	+	41	5917	c.5870G>A	c.(5869-5871)gGc>gAc	p.G1957D	MYH14_uc002prq.1_Missense_Mutation_p.G1924D|MYH14_uc002prr.1_Missense_Mutation_p.G1916D|MYH14_uc010ycb.2_Missense_Mutation_p.G267D|MYH14_uc002prs.1_Missense_Mutation_p.G267D	NM_001145809	NP_001139281	Q7Z406	MYH14_HUMAN	Homo sapiens myosin, heavy chain 14, non-muscle (MYH14), transcript variant 3, mRNA.	1916					axon guidance|regulation of cell shape	myosin complex	ATP binding|actin binding|calmodulin binding|motor activity			central_nervous_system(1)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(10)|ovary(1)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)	46		all_neural(266;0.0571)|Ovarian(192;0.0728)		OV - Ovarian serous cystadenocarcinoma(262;0.00389)|GBM - Glioblastoma multiforme(134;0.0195)		GCTCAGGCCGGCCGCCGGAGG	0.627000													3	100					0	0	1	0	0
GGT8P	645367	broad.mit.edu	37	2	91968570	91968570	+	RNA	SNP	G	G	A			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr2:91968570G>A	uc010fho.1	+	1		c.901G>A								Homo sapiens gamma-glutamyltransferase 8 pseudogene (GGT8P), non-coding RNA.																		CGTGGGCAAGGGCTTGGCAGC	0.667000													10	62					0	0	1	0	0
GMIP	51291	broad.mit.edu	37	19	19750895	19750895	+	Splice_Site	SNP	T	T	C			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr19:19750895T>C	uc002nnd.3	-	7	654	c.537_splice	c.e7+1	p.Q179_splice	GMIP_uc010xrb.2_Splice_Site_p.Q179_splice|GMIP_uc010xrc.2_Splice_Site_p.Q179_splice	NM_016573	NP_057657	Q9P107	GMIP_HUMAN	Homo sapiens GEM interacting protein (GMIP), mRNA.	179					negative regulation of Rho GTPase activity|small GTPase mediated signal transduction	cytosol	Rho GTPase activator activity|metal ion binding|protein binding			breast(1)|endometrium(6)|kidney(1)|large_intestine(2)|lung(9)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	24						CCCCCTCACCTGGTAGTAGTC	0.577000													11	32					0	0	1	0	0
MYH10	4628	broad.mit.edu	37	17	8397110	8397110	+	Missense_Mutation	SNP	C	C	G			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr17:8397110C>G	uc002glm.3	-	31	4246	c.4150G>C	c.(4150-4152)Gag>Cag	p.E1384Q	MYH10_uc002gll.3_Missense_Mutation_p.E1353Q|MYH10_uc010cnx.3_Missense_Mutation_p.E1362Q	NM_005964	NP_005955	P35580	MYH10_HUMAN	Homo sapiens myosin, heavy chain 10, non-muscle (MYH10), transcript variant 2, mRNA.	1353					actin filament-based movement|axon guidance|cytokinesis after mitosis|regulation of cell shape	cell cortex|cleavage furrow|midbody|myosin complex|stress fiber	ADP binding|ATP binding|actin filament binding|actin-dependent ATPase activity|calmodulin binding|microfilament motor activity			breast(5)|endometrium(9)|kidney(2)|large_intestine(16)|lung(9)|ovary(3)|prostate(3)|skin(4)|stomach(1)	52						TCCTCCTCCTCCTGCTGCTCC	0.587000													3	52					0	0	1	0	0
ESPN	83715	broad.mit.edu	37	1	6511719	6511719	+	Missense_Mutation	SNP	G	G	C			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr1:6511719G>C	uc001amy.3	+	8	2140	c.1972G>C	c.(1972-1974)Gag>Cag	p.E658Q	ESPN_uc001amz.3_Missense_Mutation_p.E92Q	NM_031475	NP_113663	B1AK53	ESPN_HUMAN	Homo sapiens espin (ESPN), mRNA.	658	Pro-rich.|WH2.				sensory perception of sound	brush border|cytoplasm|filamentous actin|stereocilium	SH3 domain binding|actin filament binding			NS(1)|breast(2)|cervix(1)|kidney(1)|large_intestine(2)|lung(7)|ovary(1)|prostate(1)|skin(1)	17	Ovarian(185;0.0386)|all_lung(157;0.154)	all_cancers(23;3.6e-37)|all_epithelial(116;2.56e-22)|all_lung(118;7.57e-07)|Lung NSC(185;4.26e-06)|all_hematologic(16;6.92e-06)|Colorectal(325;4.47e-05)|Acute lymphoblastic leukemia(12;4.92e-05)|Breast(487;7.61e-05)|Renal(390;0.0007)|Hepatocellular(190;0.00308)|Myeloproliferative disorder(586;0.0255)|Ovarian(437;0.0392)		Epithelial(90;1.82e-35)|GBM - Glioblastoma multiforme(13;3e-28)|Kidney(185;3.04e-09)|KIRC - Kidney renal clear cell carcinoma(229;5.63e-08)|Colorectal(212;7e-08)|COAD - Colon adenocarcinoma(227;1.41e-05)|BRCA - Breast invasive adenocarcinoma(365;0.000109)|STAD - Stomach adenocarcinoma(132;0.00167)|Lung(427;0.0108)|LUSC - Lung squamous cell carcinoma(448;0.0253)|READ - Rectum adenocarcinoma(331;0.0419)		GCTACTGGCTGAGATTAAGGC	0.637000													5	22					0	0	1	0	0
IGSF10	285313	broad.mit.edu	37	3	151171242	151171242	+	Silent	SNP	G	G	A			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr3:151171242G>A	uc011bod.2	-	2	645	c.645C>T	c.(643-645)taC>taT	p.Y215Y		NM_178822	NP_849144	Q6WRI0	IGS10_HUMAN	Homo sapiens immunoglobulin superfamily, member 10 (IGSF10), transcript variant 1, mRNA.	215					cell differentiation|multicellular organismal development|ossification	extracellular region				NS(1)|breast(1)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(24)|liver(4)|lung(43)|ovary(8)|prostate(4)|skin(9)|stomach(1)|urinary_tract(3)	116			LUSC - Lung squamous cell carcinoma(72;0.0394)|Lung(72;0.0517)			TTCCATGCAGGTAAAGGCTGT	0.413000													3	107					0	0	1	0	0
ARFGAP2	84364	broad.mit.edu	37	11	47189578	47189578	+	Missense_Mutation	SNP	A	A	G			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr11:47189578A>G	uc001ndt.3	-	11	1359	c.1087T>C	c.(1087-1089)Ttt>Ctt	p.F363L	ARFGAP2_uc010rha.2_Missense_Mutation_p.F94L|ARFGAP2_uc010rhb.2_Missense_Mutation_p.F335L|ARFGAP2_uc001ndu.3_Missense_Mutation_p.F227L|ARFGAP2_uc010rhc.2_Missense_Mutation_p.F94L	NM_032389	NP_115765	Q8N6H7	ARFG2_HUMAN	Homo sapiens ADP-ribosylation factor GTPase activating protein 2 (ARFGAP2), transcript variant 1, mRNA.	363	Required for interaction with coatomer.				protein transport|regulation of ARF GTPase activity|vesicle-mediated transport	Golgi membrane|nucleolus|plasma membrane	ARF GTPase activator activity|zinc ion binding			breast(2)|kidney(2)|large_intestine(5)|lung(7)|ovary(3)|prostate(1)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	23						CCTAAGGAAAAGGGATTGTCC	0.512000													3	61					0	0	1	0	0
CACNG7	59284	broad.mit.edu	37	19	54416099	54416099	+	Missense_Mutation	SNP	G	G	T			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr19:54416099G>T	uc002qcr.2	+	0	109	c.14G>T	c.(13-15)aGc>aTc	p.S5I	CACNG7_uc010era.2_Missense_Mutation_p.S5I	NM_031896	NP_114102	P62955	CCG7_HUMAN	Homo sapiens calcium channel, voltage-dependent, gamma subunit 7 (CACNG7), mRNA.	5					regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex|voltage-gated calcium channel complex	voltage-gated calcium channel activity	p.C4S(1)		NS(1)|kidney(1)|large_intestine(6)|lung(12)|ovary(1)|prostate(1)|upper_aerodigestive_tract(1)	23	all_cancers(19;0.0462)|all_epithelial(19;0.0258)|all_lung(19;0.185)|Ovarian(34;0.19)|Lung NSC(19;0.218)			GBM - Glioblastoma multiforme(134;0.0711)		AGTCACTGCAGCAGCCGCGCC	0.637000											OREG0003671	type=REGULATORY REGION|Gene=CACNG7|Dataset=Stanford ENCODE Dataset|EvidenceSubtype=Transient transfection luciferase assay	3	72					0	0	1	0	0
TRIM8	81603	broad.mit.edu	37	10	104416787	104416787	+	Silent	SNP	G	G	A			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr10:104416787G>A	uc001kvz.2	+	5	1455	c.1332G>A	c.(1330-1332)tcG>tcA	p.S444S		NM_030912	NP_112174	Q9BZR9	TRIM8_HUMAN	Homo sapiens tripartite motif containing 8 (TRIM8), mRNA.	444						PML body|cytoplasm	ligase activity|protein homodimerization activity|zinc ion binding			endometrium(4)|kidney(1)|large_intestine(2)|lung(5)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	15		Colorectal(252;0.122)		Epithelial(162;3.93e-09)|all cancers(201;1.02e-07)|BRCA - Breast invasive adenocarcinoma(275;0.215)		TCCCCCCATCGCAGTATCCCA	0.657000													3	70					0	0	1	0	0
HSF4	3299	broad.mit.edu	37	16	67203680	67203680	+	Missense_Mutation	SNP	T	T	C			TCGA-FK-A3SB-01A-11D-A22D-08	TCGA-FK-A3SB-10A-01D-A22D-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	f5c194a9-c0e9-4c8a-8d3c-01edd70bdbd7	c7f4c035-cf6d-455d-9f91-540c961ceb34	g.chr16:67203680T>C	uc002erl.2	+	14	2436	c.1471T>C	c.(1471-1473)Tcc>Ccc	p.S491P	HSF4_uc002erm.2_Missense_Mutation_p.S461P|HSF4_uc002ern.1_Non-coding_Transcript|HSF4_uc010cec.1_Non-coding_Transcript|NOL3_uc010vjc.2_5'Flank	NM_001040667	NP_001035757	Q9ULV5	HSF4_HUMAN	Homo sapiens heat shock transcription factor 4 (HSF4), transcript variant 2, mRNA.	491					response to stress	nucleus	sequence-specific DNA binding transcription factor activity|transcription corepressor activity			central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(1)|lung(3)|prostate(1)|skin(1)	12		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0143)|Epithelial(162;0.0335)|all cancers(182;0.184)		AGCCAGTCCCTCCCCCTAAGA	0.662000											OREG0023873	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	109					0	0	1	0	0