Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ABL2	27	broad.mit.edu	37	1	179090742	179090742	+	Silent	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr1:179090742C>T	uc001gmj.4	-	4	1235	c.948G>A	c.(946-948)gtG>gtA	p.V316V	ABL2_uc010pnf.2_Silent_p.V316V|ABL2_uc010png.2_Silent_p.V295V|ABL2_uc010pnh.2_Silent_p.V295V|ABL2_uc009wxe.3_Silent_p.V295V|ABL2_uc001gmg.4_Silent_p.V301V|ABL2_uc001gmi.4_Silent_p.V301V|ABL2_uc010pne.2_Silent_p.V280V|ABL2_uc001gmk.3_Silent_p.V280V|ABL2_uc009wxf.2_Silent_p.V301V	NM_007314	NP_009298	P42684	ABL2_HUMAN	Homo sapiens v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2), transcript variant b, mRNA.	316	Protein kinase.				axon guidance|cell adhesion|peptidyl-tyrosine phosphorylation|positive regulation of oxidoreductase activity|signal transduction	cytoskeleton|cytosol	ATP binding|magnesium ion binding|manganese ion binding|non-membrane spanning protein tyrosine kinase activity|protein binding			breast(8)|central_nervous_system(1)|endometrium(7)|kidney(1)|large_intestine(9)|lung(32)|ovary(3)|prostate(2)|skin(1)|upper_aerodigestive_tract(1)	65					Adenosine triphosphate(DB00171)|Dasatinib(DB01254)	TCAATGTTTTCACAGCAACTG	0.428000			T	ETV6	AML								9	232					0	0	1	0	0
FLII	2314	broad.mit.edu	37	17	18149316	18149316	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr17:18149316C>T	uc002gsr.1	-	25	3379	c.3328G>A	c.(3328-3330)Gac>Aac	p.D1110N	FLII_uc002gsq.1_Missense_Mutation_p.D981N|FLII_uc010vxn.1_Missense_Mutation_p.D1079N|FLII_uc010vxo.1_Missense_Mutation_p.D1055N	NM_002018	NP_002009	Q13045	FLII_HUMAN	Homo sapiens flightless I homolog (Drosophila) (FLII), transcript variant 1, mRNA.	1110					multicellular organismal development|muscle contraction|regulation of transcription, DNA-dependent|transcription, DNA-dependent	centrosome|nucleus	actin binding			central_nervous_system(2)|endometrium(5)|kidney(1)|large_intestine(6)|lung(11)|ovary(2)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	32	all_neural(463;0.228)					TCGTCAGGGTCTGATGCCCGG	0.617000													21	43					0	0	1	0	0
CORO2A	7464	broad.mit.edu	37	9	100919655	100919655	+	Silent	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr9:100919655G>A	uc004ayn.2	-	1	404	c.288C>T	c.(286-288)tcC>tcT	p.S96S	CORO2A_uc004ayl.3_Intron|CORO2A_uc004aym.3_Intron			Q92828	COR2A_HUMAN	Homo sapiens coronin, actin binding protein, 2A (CORO2A), transcript variant 2, mRNA.	0					actin cytoskeleton organization|intracellular signal transduction	actin cytoskeleton|transcriptional repressor complex	actin filament binding			endometrium(2)|kidney(2)|large_intestine(8)|lung(7)|ovary(1)|pancreas(1)|skin(4)|urinary_tract(1)	26		Acute lymphoblastic leukemia(62;0.0559)				ggcagggctaggactttctag	0.512000													5	14					0	0	1	0	0
ADAM29	11086	broad.mit.edu	37	4	175897117	175897117	+	Silent	SNP	T	T	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr4:175897117T>C	uc003iuc.3	+	4	1111	c.441T>C	c.(439-441)caT>caC	p.H147H	ADAM29_uc003iud.3_Silent_p.H147H|ADAM29_uc010irr.3_Silent_p.H147H|ADAM29_uc011cki.2_Silent_p.H147H|ADAM29_uc021xuo.1_Silent_p.H147H	NM_014269	NP_055084	Q9UKF5	ADA29_HUMAN	Homo sapiens ADAM metallopeptidase domain 29 (ADAM29), transcript variant 1, mRNA.	147					proteolysis|spermatogenesis	integral to plasma membrane	metalloendopeptidase activity|zinc ion binding			NS(1)|breast(1)|central_nervous_system(3)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(16)|lung(25)|ovary(3)|pancreas(1)|prostate(7)|skin(24)|urinary_tract(2)	93		Breast(14;0.00908)|Melanoma(52;0.00951)|Prostate(90;0.00996)|Renal(120;0.0183)|all_hematologic(60;0.107)|all_neural(102;0.164)		all cancers(43;3.08e-19)|Epithelial(43;6.24e-18)|OV - Ovarian serous cystadenocarcinoma(60;1.78e-09)|STAD - Stomach adenocarcinoma(60;0.00303)|GBM - Glioblastoma multiforme(59;0.0106)|LUSC - Lung squamous cell carcinoma(193;0.0286)		CGTTTGAACATCTGGTATACA	0.368000													46	78					0	0	1	0	0
USP9Y	8287	broad.mit.edu	37	Y	14924964	14924964	+	Missense_Mutation	SNP	A	A	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chrY:14924964A>C	uc004fst.1	+	30	5531	c.4586A>C	c.(4585-4587)tAt>tCt	p.Y1529S	USP9Y_uc010nwu.1_Non-coding_Transcript	NM_004654	NP_004645	O00507	USP9Y_HUMAN	Homo sapiens ubiquitin specific peptidase 9, Y-linked (USP9Y), mRNA.	1529					BMP signaling pathway|protein deubiquitination|spermatogenesis|transforming growth factor beta receptor signaling pathway|ubiquitin-dependent protein catabolic process	cytoplasm	co-SMAD binding|ubiquitin thiolesterase activity|ubiquitin-specific protease activity			kidney(1)|large_intestine(8)|lung(5)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	17						ACTGAAATGTATTACATGGGC	0.333000													29	8					0	0	1	0	0
PRDM2	7799	broad.mit.edu	37	1	14075951	14075951	+	Silent	SNP	G	G	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr1:14075951G>C	uc001avi.3	+	5	1336	c.480G>C	c.(478-480)cgG>cgC	p.R160R	PRDM2_uc001avg.3_Silent_p.R160R|PRDM2_uc001avh.3_Silent_p.R160R|PRDM2_uc021ogk.1_5'UTR|PRDM2_uc001avk.3_5'UTR|PRDM2_uc009voe.3_Non-coding_Transcript|PRDM2_uc009vof.3_Non-coding_Transcript	NM_012231	NP_036363	Q13029	PRDM2_HUMAN	Homo sapiens PR domain containing 2, with ZNF domain (PRDM2), transcript variant 1, mRNA.	160						Golgi apparatus|nucleus	DNA binding|histone-lysine N-methyltransferase activity|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(16)|lung(20)|ovary(3)|prostate(3)|skin(1)|urinary_tract(2)	55	Ovarian(185;0.249)	all_lung(284;2.56e-05)|Lung NSC(185;4.94e-05)|Renal(390;0.000147)|Breast(348;0.000162)|Colorectal(325;0.00058)|Ovarian(437;0.00965)|Hepatocellular(190;0.0245)|Myeloproliferative disorder(586;0.0255)	GBM - Glioblastoma multiforme(2;0.00182)	UCEC - Uterine corpus endometrioid carcinoma (279;0.00224)|Colorectal(212;3.23e-08)|BRCA - Breast invasive adenocarcinoma(304;2.16e-05)|COAD - Colon adenocarcinoma(227;2.53e-05)|Kidney(185;0.000762)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.00446)|READ - Rectum adenocarcinoma(331;0.0276)|Lung(427;0.145)		CCAGCGCCCGGAGCAAGCGGA	0.726000													13	6					0	0	1	0	0
CLIP2	7461	broad.mit.edu	37	7	73731926	73731926	+	Missense_Mutation	SNP	C	C	G			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr7:73731926C>G	uc003uam.3	+	1	377	c.50C>G	c.(49-51)tCc>tGc	p.S17C	CLIP2_uc003uan.3_Missense_Mutation_p.S17C	NM_003388	NP_003379	Q9UDT6	CLIP2_HUMAN	Homo sapiens CAP-GLY domain containing linker protein 2 (CLIP2), transcript variant 1, mRNA.	17						microtubule associated complex				breast(1)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(7)|lung(13)|pancreas(1)|prostate(2)|skin(3)	30						GGGAAGCACTCCAGCCCCATG	0.672000													65	80					0	0	1	0	0
ARHGEF15	22899	broad.mit.edu	37	17	8218800	8218800	+	Silent	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr17:8218800C>T	uc002glc.3	+	6	1484	c.1329C>T	c.(1327-1329)ttC>ttT	p.F443F	ARHGEF15_uc002gld.3_Silent_p.F443F|ARHGEF15_uc010vuw.2_Silent_p.F332F	NM_173728	NP_776089	O94989	ARHGF_HUMAN	Homo sapiens Rho guanine nucleotide exchange factor (GEF) 15 (ARHGEF15), transcript variant 1, mRNA.	443	DH.				negative regulation of synapse maturation|regulation of Rho protein signal transduction	dendrite|intracellular	GTPase activator activity|Rho guanyl-nucleotide exchange factor activity			breast(1)|endometrium(9)|large_intestine(5)|lung(11)|ovary(5)|prostate(3)|skin(2)|urinary_tract(1)	37						CCGACACCTTCGTGCTGAGCC	0.617000													50	127					0	0	1	0	0
DHX8	1659	broad.mit.edu	37	17	41585706	41585706	+	Splice_Site	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr17:41585706G>A	uc002idu.1	+	16	2393	c.2321_splice	c.e16-1	p.G774_splice	DHX8_uc010wif.1_Splice_Site_p.G683_splice|DHX8_uc010wig.2_Splice_Site_p.G774_splice	NM_004941	NP_004932	Q14562	DHX8_HUMAN	Homo sapiens DEAH (Asp-Glu-Ala-His) box polypeptide 8 (DHX8), mRNA.	774	Helicase C-terminal.					catalytic step 2 spliceosome	ATP binding|ATP-dependent RNA helicase activity|RNA binding|protein binding			breast(1)|central_nervous_system(1)|endometrium(3)|kidney(3)|large_intestine(9)|lung(17)|ovary(2)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(1)	42		Breast(137;0.00908)		BRCA - Breast invasive adenocarcinoma(366;0.08)		TCTGCTCGTAGGTGATATCCT	0.388000													43	84					0	0	1	0	0
DNAH9	1770	broad.mit.edu	37	17	11757354	11757354	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr17:11757354C>T	uc002gne.3	+	49	9610	c.9542C>T	c.(9541-9543)cCg>cTg	p.P3181L	DNAH9_uc010coo.3_Missense_Mutation_p.P2475L	NM_001372	NP_001363	Q9NYC9	DYH9_HUMAN	Homo sapiens dynein, axonemal, heavy chain 9 (DNAH9), transcript variant 2, mRNA.	3181	Stalk (By similarity).				cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity	p.P3181Q(2)		NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4)	290		Breast(5;0.0122)|all_epithelial(5;0.131)		Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157)		TTTGGCTCTCCGCCTCTGGCC	0.572000													36	47					0	0	1	0	0
SRC	6714	broad.mit.edu	37	20	36031692	36031692	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr20:36031692G>C	uc002xgx.3	+	13	1970	c.1521G>C	c.(1519-1521)gaG>gaC	p.E507D	SRC_uc002xgy.3_Missense_Mutation_p.E507D|SRC_uc021wdd.1_Non-coding_Transcript	NM_005417	NP_938033	P12931	SRC_HUMAN	Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, mRNA.	507	Protein kinase.				Ras protein signal transduction|T cell costimulation|axon guidance|bone resorption|cell junction assembly|cellular membrane organization|epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|interspecies interaction between organisms|intracellular protein kinase cascade|leukocyte migration|nerve growth factor receptor signaling pathway|platelet activation|positive regulation of integrin activation|regulation of bone resorption|regulation of vascular permeability|response to interleukin-1|signal complex assembly	caveola|cytosol|mitochondrial inner membrane	ATP binding|SH2 domain binding|SH3/SH2 adaptor activity|heme binding|integrin binding|ion channel binding|non-membrane spanning protein tyrosine kinase activity			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(2)|large_intestine(16)|lung(4)|ovary(1)|prostate(1)|urinary_tract(1)	30		Myeloproliferative disorder(115;0.00878)			Dasatinib(DB01254)	AGGAGCCTGAGGAGCGGCCCA	0.677000													3	15					0	0	1	0	0
CIRH1A	84916	broad.mit.edu	37	16	69200994	69200994	+	Missense_Mutation	SNP	A	A	G			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr16:69200994A>G	uc002ews.4	+	15	1946	c.1850A>G	c.(1849-1851)aAa>aGa	p.K617R	CIRH1A_uc002ewr.2_3'UTR|CIRH1A_uc002ewt.4_Missense_Mutation_p.K534R|CIRH1A_uc010cfi.3_Missense_Mutation_p.K419R	NM_032830	NP_116219	Q969X6	CIR1A_HUMAN	Homo sapiens cirrhosis, autosomal recessive 1A (cirhin) (CIRH1A), mRNA.	617						nucleolus	protein binding			breast(2)|endometrium(1)|kidney(3)|large_intestine(4)|lung(4)|prostate(1)|urinary_tract(1)	16				OV - Ovarian serous cystadenocarcinoma(108;0.125)		CCAAATGACAAAACCTTACTC	0.378000													59	70					0	0	1	0	0
TMEM176B	28959	broad.mit.edu	37	7	150490266	150490266	+	Silent	SNP	G	G	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr7:150490266G>C	uc022apx.1	-	3	636	c.510C>G	c.(508-510)gtC>gtG	p.V170V	TMEM176B_uc003whu.4_Silent_p.V170V|TMEM176B_uc003whv.4_Silent_p.V133V|TMEM176B_uc003whw.4_Silent_p.V170V	NM_014020	NP_054739	Q3YBM2	T176B_HUMAN	Homo sapiens transmembrane protein 176B (TMEM176B), transcript variant 1, mRNA.	170					cell differentiation|organ morphogenesis	integral to membrane|nuclear membrane				cervix(1)|large_intestine(4)|lung(10)|ovary(1)|skin(3)	19			OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)		TGGTAGGGAAGACAGGGTCTG	0.507000													53	69					0	0	1	0	0
CYTH1	9267	broad.mit.edu	37	17	76695039	76695039	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr17:76695039C>T	uc021ueg.1	-	7	633	c.562G>A	c.(562-564)Gtc>Atc	p.V188I	CYTH1_uc002jvw.3_Missense_Mutation_p.V188I|U6_uc021ueh.1_5'Flank|CYTH1_uc010wtw.1_Missense_Mutation_p.V129I|CYTH1_uc010wtx.1_Missense_Mutation_p.V129I	NM_004762	NP_004753	Q15438	CYH1_HUMAN	Homo sapiens cytohesin 1 (CYTH1), transcript variant 1, mRNA.	188	SEC7.				regulation of ARF protein signal transduction|regulation of cell adhesion|vesicle-mediated transport	cytoplasm|plasma membrane	ARF guanyl-nucleotide exchange factor activity|protein binding			endometrium(4)|kidney(1)|large_intestine(2)|lung(7)|ovary(1)|skin(2)|upper_aerodigestive_tract(2)	19						AAGGAGAGGACGTAACAAGTA	0.478000													7	232					0	0	1	0	0
MTTP	4547	broad.mit.edu	37	4	100534244	100534244	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr4:100534244G>A	uc011cej.2	+	14	2258	c.2245G>A	c.(2245-2247)Ggc>Agc	p.G749S	MTTP_uc003hvc.4_Missense_Mutation_p.G722S	NM_000253	NP_000244	P55157	MTP_HUMAN	Homo sapiens microsomal triglyceride transfer protein (MTTP), mRNA.	722					lipid metabolic process|lipoprotein metabolic process	endoplasmic reticulum lumen	lipid binding|lipid transporter activity			breast(3)|central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(3)|large_intestine(14)|lung(19)|ovary(4)|prostate(5)|skin(1)|urinary_tract(1)	57				OV - Ovarian serous cystadenocarcinoma(123;6.04e-09)	Hesperetin(DB01094)	GTCAGCATCTGGCGACCCTAT	0.423000													3	75					0	0	1	0	0
KIAA0556	23247	broad.mit.edu	37	16	27763240	27763240	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr16:27763240G>C	uc002dow.3	+	16	3571	c.3547G>C	c.(3547-3549)Gaa>Caa	p.E1183Q		NM_015202	NP_056017	O60303	K0556_HUMAN	Homo sapiens KIAA0556 (KIAA0556), mRNA.	1183										breast(4)|endometrium(7)|kidney(8)|large_intestine(17)|lung(24)|ovary(5)|prostate(3)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	76						GGGGGCTGATGAACGGGTAGG	0.612000													22	20					0	0	1	0	0
NUDT15	55270	broad.mit.edu	37	13	48611888	48611888	+	Silent	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr13:48611888G>A	uc001vbw.1	+	0	186	c.6G>A	c.(4-6)acG>acA	p.T2T	SUCLA2_uc010tgd.2_5'UTR|NUDT15_uc001vbv.3_Silent_p.T2T	NM_018283	NP_060753	Q9NV35	NUD15_HUMAN	Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 15 (NUDT15), mRNA.	2							hydrolase activity|metal ion binding			endometrium(1)|kidney(3)|large_intestine(2)|lung(1)	7		all_cancers(8;3.75e-25)|all_epithelial(8;1.78e-13)|all_lung(13;2.85e-06)|Breast(56;0.000141)|all_hematologic(8;0.000219)|Lung NSC(96;0.000226)|Prostate(109;0.00132)|Acute lymphoblastic leukemia(8;0.0167)|Myeloproliferative disorder(33;0.039)|Hepatocellular(98;0.0556)|Lung SC(185;0.102)|Glioma(44;0.236)		GBM - Glioblastoma multiforme(144;4.83e-07)		GCGCTATGACGGCCAGCGCAC	0.721000											OREG0022405	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	0					0	0	1	0	0
NBPF10	100132406	broad.mit.edu	37	1	145293460	145293460	+	Missense_Mutation	SNP	G	G	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr1:145293460G>C	uc021oul.1	+	0	90	c.55G>C	c.(55-57)Gaa>Caa	p.E19Q	NBPF10_uc021ots.1_Intron|NBPF10_uc010oye.2_Intron|NBPF10_uc010oyh.1_Non-coding_Transcript|NBPF10_uc021ouk.1_Missense_Mutation_p.E19Q|NBPF10_uc001emq.1_Missense_Mutation_p.E19Q	NM_001039703	NP_001034792	A6NDV3	A6NDV3_HUMAN	Homo sapiens neuroblastoma breakpoint family, member 10 (NBPF10), mRNA.	19										NS(3)|breast(1)|central_nervous_system(3)|endometrium(12)|kidney(23)|lung(15)|ovary(1)|prostate(7)|skin(6)|urinary_tract(2)	73	all_hematologic(923;0.032)			Colorectal(1306;1.36e-07)|KIRC - Kidney renal clear cell carcinoma(1967;0.00258)		GAACATTCTAGAAATCAACGA	0.522000													96	650					0	0	1	0	0
GNPAT	8443	broad.mit.edu	37	1	231401089	231401089	+	Missense_Mutation	SNP	T	T	C			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr1:231401089T>C	uc001hup.4	+	4	825	c.619T>C	c.(619-621)Ttt>Ctt	p.F207L	GNPAT_uc009xfo.1_Missense_Mutation_p.F98L|GNPAT_uc009xfp.3_Missense_Mutation_p.F146L	NM_014236	NP_055051	O15228	GNPAT_HUMAN	Homo sapiens glyceronephosphate O-acyltransferase (GNPAT), mRNA.	207					ether lipid biosynthetic process|fatty acid metabolic process|organ morphogenesis	peroxisomal matrix|peroxisomal membrane	glycerone-phosphate O-acyltransferase activity			breast(2)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(2)|lung(9)|ovary(3)|prostate(1)|skin(1)	23	Breast(184;0.0871)	all_cancers(173;0.2)|Prostate(94;0.183)				GTCGGGTGCCTTTTTCATGCG	0.383000													3	92					0	0	1	0	0
PIK3CA	5290	broad.mit.edu	37	3	178952074	178952074	+	Missense_Mutation	SNP	G	G	C	rs121913283		TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr3:178952074G>C	uc003fjk.3	+	20	3286	c.3129G>C	c.(3127-3129)atG>atC	p.M1043I		NM_006218	NP_006209	P42336	PK3CA_HUMAN	Homo sapiens phosphoinositide-3-kinase, catalytic, alpha polypeptide (PIK3CA), mRNA.	1043	PI3K/PI4K.		M -> I (in cancer; shows an increase in lipid kinase activity).		T cell costimulation|T cell receptor signaling pathway|epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol-mediated signaling|platelet activation		1-phosphatidylinositol-3-kinase activity|ATP binding|phosphatidylinositol-4,5-bisphosphate 3-kinase activity	p.M1043I(128)|p.M1043V(21)|p.M1043T(4)		NS(16)|autonomic_ganglia(4)|biliary_tract(22)|bone(1)|breast(2150)|central_nervous_system(110)|cervix(33)|endometrium(473)|eye(1)|haematopoietic_and_lymphoid_tissue(35)|kidney(14)|large_intestine(1202)|liver(42)|lung(202)|meninges(1)|oesophagus(28)|ovary(235)|pancreas(17)|penis(8)|pituitary(12)|prostate(10)|skin(155)|small_intestine(1)|soft_tissue(18)|stomach(121)|thyroid(80)|upper_aerodigestive_tract(70)|urinary_tract(208)	5269	all_cancers(143;1.19e-17)|Ovarian(172;0.00769)|Breast(254;0.155)		OV - Ovarian serous cystadenocarcinoma(80;9.59e-28)|GBM - Glioblastoma multiforme(14;0.003)|BRCA - Breast invasive adenocarcinoma(182;0.0282)			TGAAACAAATGAATGATGCAC	0.368000		57	Mis		"""colorectal, gastric, gliobastoma, breast"""					HNSCC(19;0.045)|TSP Lung(28;0.18)			40	55					0	0	1	0	0
CAMK2A	815	broad.mit.edu	37	5	149602592	149602592	+	Missense_Mutation	SNP	C	C	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr5:149602592C>T	uc003lrt.2	-	17	1641	c.1426G>A	c.(1426-1428)Gtc>Atc	p.V476I	CAMK2A_uc003lru.2_Missense_Mutation_p.V465I	NM_015981	NP_057065	Q9UQM7	KCC2A_HUMAN	Homo sapiens calcium/calmodulin-dependent protein kinase II alpha (CAMK2A), transcript variant 1, mRNA.	465					interferon-gamma-mediated signaling pathway|positive regulation of NF-kappaB transcription factor activity|synaptic transmission	cell junction|cytosol|endocytic vesicle membrane|nucleoplasm|presynaptic membrane	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity	p.I475I(1)		cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(3)|lung(6)|skin(1)|stomach(1)	15		all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TGGAAGTGGACGATCTGCCAT	0.632000													57	67					0	0	1	0	0
LETM2	137994	broad.mit.edu	37	8	38264955	38264955	+	Nonsense_Mutation	SNP	G	G	T			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr8:38264955G>T	uc003xlm.2	+	9	1478	c.1246G>T	c.(1246-1248)Gga>Tga	p.G416*	LETM2_uc003xll.2_Nonsense_Mutation_p.G368*|LETM2_uc003xln.2_Nonsense_Mutation_p.G260*|LETM2_uc003xlo.2_Nonsense_Mutation_p.G260*	NM_001199659	NP_001186588	Q2VYF4	LETM2_HUMAN	Homo sapiens leucine zipper-EF-hand containing transmembrane protein 2 (LETM2), transcript variant 1, mRNA.	463						integral to membrane|mitochondrial inner membrane				NS(1)|large_intestine(1)|lung(3)|prostate(2)	7	all_cancers(2;6.77e-47)|all_epithelial(2;1.01e-50)|all_lung(3;1.25e-23)|Lung NSC(2;2.76e-23)|Colorectal(12;0.000442)|Esophageal squamous(3;0.00202)	all_lung(54;0.0657)|Hepatocellular(245;0.152)|Lung NSC(58;0.175)	Epithelial(3;1.17e-42)|all cancers(3;5.44e-38)|BRCA - Breast invasive adenocarcinoma(5;5.44e-27)|LUSC - Lung squamous cell carcinoma(2;7.12e-25)|Lung(2;4.49e-22)|COAD - Colon adenocarcinoma(9;0.114)			ATTACCTAAAGGACCCATCAC	0.388000													68	113					0	0	1	0	0
ZNF48	197407	broad.mit.edu	37	16	30409512	30409512	+	Missense_Mutation	SNP	G	G	A	rs145091254		TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr16:30409512G>A	uc021tgi.1	+	2	1055	c.941G>A	c.(940-942)cGg>cAg	p.R314Q	ZNF48_uc021tgj.1_Missense_Mutation_p.R191Q|ZNF48_uc021tgk.1_Missense_Mutation_p.R314Q|ZNF48_uc002dya.2_Missense_Mutation_p.R314Q	NM_001214906	NP_001201835	Q96MX3	ZNF48_HUMAN	Homo sapiens zinc finger protein 48 (ZNF48), transcript variant 2, mRNA.	314					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(1)|lung(11)|ovary(2)|pancreas(1)|skin(1)	21						GAGTTTGCCCGGGGATCCGAC	0.622000													43	42					0	0	1	0	0
MTMR12	54545	broad.mit.edu	37	5	32230250	32230250	+	Missense_Mutation	SNP	C	C	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr5:32230250C>A	uc003jhq.3	-	15	2048	c.1878G>T	c.(1876-1878)ttG>ttT	p.L626F	MTMR12_uc010iuk.3_Missense_Mutation_p.L572F|MTMR12_uc010iul.3_Missense_Mutation_p.L516F	NM_001040446	NP_001035536	Q9C0I1	MTMRC_HUMAN	Homo sapiens myotubularin related protein 12 (MTMR12), mRNA.	626	Myotubularin phosphatase.					cytoplasm	phosphatase activity			breast(3)|endometrium(3)|kidney(2)|large_intestine(7)|lung(11)|ovary(2)|prostate(1)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	34						GCGGTAACAACAAACCATGGT	0.483000													72	96					0	0	1	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	A	T	rs121913377		TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr7:140453136A>T	uc003vwc.4	-	14	1860	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333	NP_004324	P15056	BRAF_HUMAN	Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA.	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome				46	63					0	0	1	0	0
ARRDC5	645432	broad.mit.edu	37	19	4891083	4891083	+	Missense_Mutation	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr19:4891083G>A	uc002mbm.3	-	2	1004	c.1004C>T	c.(1003-1005)cCc>cTc	p.P335L		NM_001080523	NP_001073992	A6NEK1	ARRD5_HUMAN	Homo sapiens arrestin domain containing 5 (ARRDC5), mRNA.	335					signal transduction					endometrium(2)|kidney(1)|large_intestine(2)|lung(6)|upper_aerodigestive_tract(1)	12				UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|BRCA - Breast invasive adenocarcinoma(158;0.0257)		TGGGTTCACGGGTAACACTCC	0.512000													38	56					0	0	1	0	0
ABP1	26	broad.mit.edu	37	7	150558122	150558122	+	Missense_Mutation	SNP	T	T	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr7:150558122T>A	uc003wia.1	+	4	2228	c.2138T>A	c.(2137-2139)tTc>tAc	p.F713Y	ABP1_uc003why.1_Missense_Mutation_p.F694Y|ABP1_uc003whz.1_Missense_Mutation_p.F694Y	NM_001091	NP_001082	P19801	ABP1_HUMAN	Homo sapiens amiloride binding protein 1 (amine oxidase (copper-containing)) (ABP1), mRNA.	694					amine metabolic process	extracellular space|peroxisome	copper ion binding|diamine oxidase activity|heparin binding|histamine oxidase activity|methylputrescine oxidase activity|primary amine oxidase activity|propane-1,3-diamine oxidase activity|quinone binding			NS(1)|breast(4)|endometrium(2)|kidney(4)|large_intestine(3)|lung(18)|ovary(3)|prostate(2)|skin(3)|stomach(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	45	all_neural(206;0.219)		OV - Ovarian serous cystadenocarcinoma(82;0.0121)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)	Amiloride(DB00594)|Spermine(DB00127)	TCCGTGGGCTTCCTGCTCCGG	0.627000													41	50					0	0	1	0	0
INTS1	26173	broad.mit.edu	37	7	1542823	1542823	+	Silent	SNP	G	G	A			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr7:1542823G>A	uc003skn.2	-	2	164	c.63C>T	c.(61-63)caC>caT	p.H21H	INTS1_uc003skq.2_Silent_p.H21H	NM_001080453	NP_001073922	Q8N201	INT1_HUMAN	Homo sapiens integrator complex subunit 1 (INTS1), mRNA.	21					snRNA processing	integral to membrane|integrator complex|nuclear membrane				autonomic_ganglia(1)|cervix(1)|endometrium(14)|kidney(3)|large_intestine(7)|lung(24)|ovary(1)|prostate(4)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	62		Ovarian(82;0.0253)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0181)|OV - Ovarian serous cystadenocarcinoma(56;6.99e-15)		CTGGGGGAGGGTGCCCTGCAG	0.542000													30	50					0	0	1	0	0
ZNF337	26152	broad.mit.edu	37	20	25656557	25656557	+	Frame_Shift_Del	DEL	T	T	-			TCGA-BJ-A3EZ-01A-11D-A202-08	TCGA-BJ-A3EZ-10A-01D-A202-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5ec345a2-a9b0-4c70-a967-9616460830b6	447950c6-32d0-4916-a3ca-d3d0ed83a32f	g.chr20:25656557delT	uc002wva.3	-	3	1889	c.1367delA	c.(1366-1368)gagfs	p.E456fs	ZNF337_uc002wuz.3_Non-coding_Transcript|ZNF337_uc010ztg.2_Frame_Shift_Del_p.E424fs|ZNF337_uc002wvc.3_Frame_Shift_Del_p.E456fs	NM_015655	NP_056470			Homo sapiens zinc finger protein 337 (ZNF337), mRNA.											breast(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(9)|lung(8)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	32						AGGCTTCTCCTCTGAGTGTGT	0.453													99	132	---	---	---	---