Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	validation_method	t_ref_count	validation_status	validation_tumor_sample	t_alt_count	validation_alt_allele	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
FAT3	120114	broad.mit.edu	37	11	92523221	92523221	+	Missense_Mutation	SNP	A	C	C			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr11:92523221A>C	uc001pdj.4	+	6	4465	c.4448A>C	c.(4447-4449)gAa>gCa	p.E1483A		NM_001008781	NP_001008781	Q8TDW7	FAT3_HUMAN	Homo sapiens FAT tumor suppressor homolog 3 (Drosophila) (FAT3), mRNA.	1483	Cadherin 14.				homophilic cell adhesion|multicellular organismal development	integral to membrane|plasma membrane	calcium ion binding			NS(1)|breast(2)|endometrium(10)|kidney(4)|large_intestine(11)|liver(2)|lung(37)|ovary(5)|pancreas(1)|prostate(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(5)	85		Acute lymphoblastic leukemia(157;3.01e-05)|all_hematologic(158;0.00858)				CTGCAGATTGAAGCCACAGAT	0.473000										TCGA Ovarian(4;0.039)				184			127		0	0	0.000781405	0	0
GABRE	2564	broad.mit.edu	37	X	151128359	151128359	+	Missense_Mutation	SNP	C	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chrX:151128359C>A	uc004ffi.3	-	5	790	c.736G>T	c.(736-738)Gat>Tat	p.D246Y	GABRE_uc011myd.2_Non-coding_Transcript|GABRE_uc011mye.1_Non-coding_Transcript|MIR452_uc022cgx.1_5'Flank	NM_004961	NP_004952	P78334	GBRE_HUMAN	Homo sapiens gamma-aminobutyric acid (GABA) A receptor, epsilon (GABRE), mRNA.	246					gamma-aminobutyric acid signaling pathway	cell junction|chloride channel complex|integral to plasma membrane|postsynaptic membrane	GABA-A receptor activity|chloride channel activity|extracellular ligand-gated ion channel activity	p.A246V(1)		breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(9)|ovary(2)|skin(1)	27	Acute lymphoblastic leukemia(192;6.56e-05)					CCTGTAAAATCAAACTGGAAG	0.443000														64			31		2.80507e-11	1.78258e-10	0.000409698	1	0
HJURP	55355	broad.mit.edu	37	2	234749833	234749833	+	Missense_Mutation	SNP	G	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr2:234749833G>T	uc002vvg.3	-	7	1659	c.1593C>A	c.(1591-1593)caC>caA	p.H531Q	HJURP_uc010znd.2_Missense_Mutation_p.H470Q|HJURP_uc010zne.2_Missense_Mutation_p.H439Q	NM_018410	NP_060880	Q8NCD3	HJURP_HUMAN	Homo sapiens Holliday junction recognition protein (HJURP), mRNA.	531					CenH3-containing nucleosome assembly at centromere|cell cycle|centromeric core chromatin assembly|chromosome segregation|regulation of DNA binding|regulation of protein complex assembly	condensed chromosome kinetochore|cytoplasm|nucleolus|nucleoplasm	DNA binding|histone binding			NS(2)|breast(2)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(3)|kidney(3)|large_intestine(3)|lung(11)|ovary(2)|prostate(3)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	38		Breast(86;0.00204)|all_lung(227;0.00433)|Renal(207;0.00685)|all_hematologic(139;0.0116)|Acute lymphoblastic leukemia(138;0.0326)|Lung NSC(271;0.0719)|Lung SC(224;0.128)		Epithelial(121;2.01e-18)|BRCA - Breast invasive adenocarcinoma(100;0.000186)|Lung(119;0.00521)|LUSC - Lung squamous cell carcinoma(224;0.00829)		GAGTTGCGCTGTGTGTGGGGT	0.488000														36			27		0.000117367	0.000680038	0.000878237	1	0
OR2B11	127623	broad.mit.edu	37	1	247614382	247614382	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr1:247614382C>T	uc010pyx.2	-	0	903	c.903G>A	c.(901-903)atG>atA	p.M301I		NM_001004492	NP_001004492	Q5JQS5	OR2BB_HUMAN	Homo sapiens olfactory receptor, family 2, subfamily B, member 11 (OR2B11), mRNA.	301					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(3)|kidney(13)|large_intestine(7)|lung(31)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)	60	all_cancers(71;4.51e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)	all_cancers(173;0.241)	OV - Ovarian serous cystadenocarcinoma(106;0.0188)			GAGCCCCCTTCATATCTTTAT	0.468000														168			71		0	0	0.000781405	0	0
TGIF2LX	90316	broad.mit.edu	37	X	89177411	89177411	+	Silent	SNP	C	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chrX:89177411C>A	uc022bzr.1	+	0	327	c.327C>A	c.(325-327)ctC>ctA	p.L109L	TGIF2LX_uc004efe.3_Silent_p.L109L	NM_138960	NP_620410	Q8IUE1	TF2LX_HUMAN	Homo sapiens TGFB-induced factor homeobox 2-like, X-linked (TGIF2LX), mRNA.	109						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(29)|ovary(1)|skin(3)|urinary_tract(1)	40						GACGCATTCTCCCGGATATGC	0.502000														62			35		1.32136e-16	8.9761e-16	0.00195071	1	0
SNX16	64089	broad.mit.edu	37	8	82714665	82714665	+	Silent	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr8:82714665C>T	uc003ycn.3	-	6	1149	c.888G>A	c.(886-888)gtG>gtA	p.V296V	SNX16_uc003yco.3_Silent_p.V267V|SNX16_uc011lft.2_Silent_p.V296V	NM_152836	NP_690049	P57768	SNX16_HUMAN	Homo sapiens sorting nexin 16 (SNX16), transcript variant 2, mRNA.	296					cell communication|early endosome to late endosome transport|endosome to lysosome transport|protein targeting to lysosome	early endosome membrane|extrinsic to endosome membrane|late endosome membrane|lysosome	identical protein binding|phosphatidylinositol binding	p.V296M(1)		large_intestine(1)|ovary(1)|pancreas(1)|skin(2)	5						CAGAGGACTCCACCTTTAGGA	0.343000														14			10		0	0	0.000442599	0	0
MBTD1	54799	broad.mit.edu	37	17	49279428	49279428	+	Silent	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr17:49279428C>T	uc002itr.4	-	10	1418	c.1074G>A	c.(1072-1074)aaG>aaA	p.K358K	MBTD1_uc002itp.4_Silent_p.K194K|MBTD1_uc002itq.4_Silent_p.K358K	NM_017643	NP_060113	Q05BQ5	MBTD1_HUMAN	Homo sapiens mbt domain containing 1 (MBTD1), mRNA.	358					chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	zinc ion binding			breast(1)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(1)|ovary(2)|skin(1)|urinary_tract(1)	12			BRCA - Breast invasive adenocarcinoma(22;1.54e-08)			CATCCTGTTTCTTTGTAATAT	0.343000														31			12		0	0	0.000308642	0	0
MAP1B	4131	broad.mit.edu	37	5	71491677	71491677	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr5:71491677C>T	uc003kbw.4	+	4	2736	c.2495C>T	c.(2494-2496)tCt>tTt	p.S832F	MAP1B_uc010iyw.1_Missense_Mutation_p.S849F|MAP1B_uc010iyx.1_Missense_Mutation_p.S706F|MAP1B_uc010iyy.1_Missense_Mutation_p.S706F	NM_005909	NP_005900	P46821	MAP1B_HUMAN	Homo sapiens microtubule-associated protein 1B (MAP1B), mRNA.	832						microtubule|microtubule associated complex	structural molecule activity			NS(1)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(42)|liver(1)|lung(28)|ovary(1)|pancreas(1)|prostate(3)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	104		Lung NSC(167;0.00202)|Ovarian(174;0.0175)|Prostate(461;0.142)|Breast(144;0.198)		OV - Ovarian serous cystadenocarcinoma(47;7.99e-54)		CTTATGTCATCTCCTGAGGAT	0.522000														54			6		0	0	0.00116845	0	0
GRM3	2913	broad.mit.edu	37	7	86468997	86468997	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr7:86468997C>T	uc003uid.3	+	3	3266	c.2167C>T	c.(2167-2169)Cgg>Tgg	p.R723W	GRM3_uc010lef.3_Intron|GRM3_uc010leg.3_Missense_Mutation_p.R595W|GRM3_uc010leh.3_Missense_Mutation_p.R315W	NM_000840	NP_000831	Q14832	GRM3_HUMAN	Homo sapiens glutamate receptor, metabotropic 3 (GRM3), mRNA.	723					synaptic transmission	integral to plasma membrane		p.R723W(2)		NS(2)|breast(6)|central_nervous_system(2)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(9)|lung(43)|ovary(3)|pancreas(2)|prostate(4)|skin(25)|upper_aerodigestive_tract(5)	109	Esophageal squamous(14;0.0058)|all_lung(186;0.132)|Lung NSC(181;0.142)				Acamprosate(DB00659)|Nicotine(DB00184)	TGCAGAGAAGCGGGAAACAGT	0.493000														10			30		0	0	0.00106085	0	0
PCDHB5	26167	broad.mit.edu	37	5	140516880	140516880	+	Missense_Mutation	SNP	G	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr5:140516880G>A	uc003liq.3	+	0	2081	c.1864G>A	c.(1864-1866)Gag>Aag	p.E622K		NM_015669	NP_056484	Q9Y5E4	PCDB5_HUMAN	Homo sapiens protocadherin beta 5 (PCDHB5), mRNA.	622	Cadherin 6.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding|protein binding	p.G621G(1)		breast(2)|central_nervous_system(1)|cervix(1)|endometrium(12)|kidney(1)|large_intestine(18)|lung(25)|ovary(3)|prostate(6)|skin(7)|upper_aerodigestive_tract(3)|urinary_tract(2)	81			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			GCACAATGGCGAGGTGCGCAC	0.706000														23			27		0	0	0.000878237	0	0
NLRP13	126204	broad.mit.edu	37	19	56423975	56423975	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr19:56423975C>T	uc010ygg.2	-	4	1233	c.1208G>A	c.(1207-1209)aGt>aAt	p.S403N		NM_176810	NP_789780	Q86W25	NAL13_HUMAN	Homo sapiens NLR family, pyrin domain containing 13 (NLRP13), mRNA.	403	NACHT.						ATP binding			NS(2)|breast(2)|central_nervous_system(1)|cervix(1)|endometrium(6)|kidney(2)|large_intestine(13)|lung(58)|ovary(4)|pancreas(2)|prostate(2)|skin(13)|stomach(2)|urinary_tract(1)	109		Colorectal(82;3.48e-05)|Ovarian(87;0.0481)|Renal(1328;0.218)		GBM - Glioblastoma multiforme(193;0.0642)		CTCAACTTCACTTGAGTCATC	0.443000														36			25		0	0	0.00047179	0	0
DCDC5	100506627	broad.mit.edu	37	11	30944050	30944050	+	Splice_Site	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr11:30944050C>T	uc009yjk.1	-	12	1546	c.1477_splice	c.e12+1	p.A493_splice	DCDC5_uc001mss.1_Splice_Site|DCDC5_uc021qfk.1_Splice_Site_p.A152_splice	NM_020869	NP_065920	Q6ZRR9	DCDC5_HUMAN	Homo sapiens doublecortin domain containing 5 (DCDC5), mRNA.	124	Doublecortin 2.				intracellular signal transduction					NS(1)|breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(3)|lung(17)|prostate(1)|stomach(1)	31						CAATGCTTACCTTCTATTTTA	0.308000														32			20		0	0	0.00152264	0	0
DDX11	1663	broad.mit.edu	37	12	31237922	31237922	+	Missense_Mutation	SNP	G	C	C			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr12:31237922G>C	uc001rjt.1	+	4	751	c.500G>C	c.(499-501)aGa>aCa	p.R167T	DDX11_uc010sjw.1_Missense_Mutation_p.R167T|DDX11_uc010sjx.1_Non-coding_Transcript|DDX11_uc001rjr.1_Missense_Mutation_p.R167T|DDX11_uc001rjs.1_Missense_Mutation_p.R167T|DDX11_uc001rju.1_5'UTR|DDX11_uc001rjv.1_Missense_Mutation_p.R167T|DDX11_uc001rjw.1_Missense_Mutation_p.R141T|DDX11_uc001rjx.1_5'Flank	NM_152438	NP_689651	Q96FC9	DDX11_HUMAN	Homo sapiens DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 (DDX11), transcript variant 3, mRNA.	167	Glu-rich.|Helicase ATP-binding.				G2/M transition of mitotic cell cycle|S phase of mitotic cell cycle|interspecies interaction between organisms|mitotic sister chromatid segregation|positive regulation of cell proliferation|sister chromatid cohesion	midbody|nuclear chromatin|nucleolus|spindle pole	ATP binding|ATP-dependent DNA helicase activity|DNA binding|RNA binding|protein binding	p.R167T(18)		breast(4)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(11)|large_intestine(5)|lung(23)|prostate(3)|skin(2)|stomach(1)|upper_aerodigestive_tract(2)	57	all_cancers(9;1.77e-11)|all_lung(12;6.21e-11)|all_epithelial(9;6.49e-11)|Lung NSC(12;1.06e-08)|Acute lymphoblastic leukemia(23;0.0122)|all_hematologic(23;0.0429)|Lung SC(12;0.0592)|Esophageal squamous(101;0.233)					GAAGAAGAAAGAGAGAATCTC	0.612000										Multiple Myeloma(12;0.14)				16			3		0	0	6.4e-05	0	0
TMEM139	135932	broad.mit.edu	37	7	142983274	142983274	+	Missense_Mutation	SNP	C	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr7:142983274C>A	uc003wcl.3	+	3	478	c.224C>A	c.(223-225)cCa>cAa	p.P75Q	CASP2_uc003wco.3_5'Flank|CASP2_uc003wcp.3_5'Flank|CASP2_uc011kta.2_5'Flank|TMEM139_uc022aoc.1_Missense_Mutation_p.P75Q|TMEM139_uc010lov.3_Missense_Mutation_p.P75Q|TMEM139_uc003wck.4_Missense_Mutation_p.P75Q|TMEM139_uc003wcn.3_Intron|TMEM139_uc022aod.1_Intron|TMEM139_uc003wcm.3_Missense_Mutation_p.P75Q	NM_001242774	NP_001229703	Q8IV31	TM139_HUMAN	Homo sapiens transmembrane protein 139 (TMEM139), transcript variant 3, mRNA.	75						integral to membrane				endometrium(1)|lung(4)|ovary(1)|prostate(1)	7	Melanoma(164;0.059)					ACTGAGAGCCCAGGGCCCTCA	0.557000														32			18		2.4624e-09	1.51591e-08	0.00121646	1	0
ANKRD30BP2	149992	broad.mit.edu	37	21	14439185	14439185	+	RNA	SNP	C	A	A	rs112098339		TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr21:14439185C>A	uc002yja.4	+	9		c.2703C>A								Homo sapiens ankyrin repeat domain 30B pseudogene 2 (ANKRD30BP2), non-coding RNA.																		TGACTTTAAACCAAGAAGAAG	0.269000														23			8		0.000274275	0.00154378	0.000274275	1	0
MYO3A	53904	broad.mit.edu	37	10	26463096	26463097	+	Missense_Mutation	DNP	GG	AA	AA			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr10:26463096_26463097GG>AA	uc001isn.2	+	29	4263_4264	c.3903_3904GG>AA	c.(3901-3906)atggaa>atAAaa	p.1301_1302ME>IK	MYO3A_uc009xkp.1_Intron|MYO3A_uc009xkq.1_Intron	NM_017433	NP_059129	Q8NEV4	MYO3A_HUMAN	Homo sapiens myosin IIIA (MYO3A), mRNA.	1301					protein autophosphorylation|response to stimulus|sensory perception of sound|visual perception	cytoplasm|filamentous actin|filopodium|myosin complex	ADP binding|ATP binding|actin binding|actin-dependent ATPase activity|calmodulin binding|plus-end directed microfilament motor activity|protein serine/threonine kinase activity			NS(2)|breast(9)|central_nervous_system(3)|endometrium(9)|kidney(10)|large_intestine(28)|liver(1)|lung(46)|ovary(11)|pancreas(1)|prostate(6)|skin(11)|stomach(6)|upper_aerodigestive_tract(1)|urinary_tract(2)	146						CAAACAGCATGGAAAAAGAAAA	0.450000														17			23		0	0	6.4e-05	0	0
HSF5	124535	broad.mit.edu	37	17	56565264	56565264	+	Silent	SNP	G	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr17:56565264G>A	uc002iwi.1	-	0	496	c.372C>T	c.(370-372)ctC>ctT	p.L124L		NM_001080439	NP_001073908	Q4G112	HSF5_HUMAN	Homo sapiens heat shock transcription factor family member 5 (HSF5), mRNA.	124						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(7)|ovary(3)|skin(1)	16	Medulloblastoma(34;0.127)|all_neural(34;0.237)					TGAGGTGCACGAGCAGCTGTG	0.711000														43			5		0	0	0.000157383	0	0
CD19	930	broad.mit.edu	37	16	28943670	28943670	+	Missense_Mutation	SNP	G	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr16:28943670G>A	uc010byo.2	+	1	154	c.92G>A	c.(91-93)gGa>gAa	p.G31E	NPIPL1_uc010vct.2_Intron|CD19_uc002drs.3_Missense_Mutation_p.G31E	NM_001178098	NP_001171569	P15391	CD19_HUMAN	Homo sapiens CD19 molecule (CD19), transcript variant 1, mRNA.	31	Ig-like C2-type 1.				cellular defense response	external side of plasma membrane|integral to plasma membrane	protein binding|receptor signaling protein activity	p.G31R(1)		NS(1)|breast(3)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(11)|ovary(2)|skin(4)|urinary_tract(1)	29						TCCACAGAGGGAGATAACGCT	0.592000														14			11		0	0	0.000673444	0	0
CELSR2	1952	broad.mit.edu	37	1	109804140	109804140	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr1:109804140C>T	uc001dxa.4	+	3	4248	c.4187C>T	c.(4186-4188)gCc>gTc	p.A1396V		NM_001408	NP_001399	Q9HCU4	CELR2_HUMAN	Homo sapiens cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) (CELSR2), mRNA.	1396	Laminin G-like 1.				Wnt receptor signaling pathway|dendrite morphogenesis|homophilic cell adhesion|neural plate anterior/posterior regionalization|neuropeptide signaling pathway|regulation of cell-cell adhesion|regulation of transcription, DNA-dependent	cytoplasm|integral to membrane|plasma membrane	G-protein coupled receptor activity|calcium ion binding|protein binding			NS(1)|autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|cervix(3)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(14)|lung(27)|ovary(5)|prostate(1)|skin(3)|urinary_tract(2)	82		all_epithelial(167;0.000114)|all_lung(203;0.000321)|Lung NSC(277;0.000626)|Breast(1374;0.244)		Colorectal(144;0.0296)|Lung(183;0.067)|COAD - Colon adenocarcinoma(174;0.114)|Epithelial(280;0.193)|all cancers(265;0.219)		TTCAGGTTTGCCACAAAGGAG	0.602000														195			6		0	0	0.000274275	0	0
SENP2	59343	broad.mit.edu	37	3	185339666	185339666	+	Missense_Mutation	SNP	A	G	G			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr3:185339666A>G	uc003fpn.3	+	13	1670	c.1499A>G	c.(1498-1500)aAg>aGg	p.K500R	SENP2_uc011brv.2_Missense_Mutation_p.K490R|SENP2_uc011brw.2_Missense_Mutation_p.K313R	NM_021627	NP_067640	Q9HC62	SENP2_HUMAN	Homo sapiens SUMO1/sentrin/SMT3 specific peptidase 2 (SENP2), mRNA.	500	Protease.				Wnt receptor signaling pathway|mRNA transport|protein desumoylation|protein transport|proteolysis|regulation of Wnt receptor signaling pathway|transmembrane transport	cytoplasm|nuclear membrane|nuclear pore	SUMO-specific protease activity|protein binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(5)|skin(3)	12	all_cancers(143;1.28e-10)|Ovarian(172;0.0386)		OV - Ovarian serous cystadenocarcinoma(80;1.31e-21)			ATGGGACAAAAGGGCCACAGG	0.388000														216			4		0	0	0.000602214	0	0
GPR112	139378	broad.mit.edu	37	X	135427555	135427555	+	Missense_Mutation	SNP	T	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chrX:135427555T>A	uc004ezu.1	+	5	1981	c.1690T>A	c.(1690-1692)Tca>Aca	p.S564T	GPR112_uc010nsb.1_Missense_Mutation_p.S359T|GPR112_uc010nsc.1_Missense_Mutation_p.S331T	NM_153834	NP_722576	Q8IZF6	GP112_HUMAN	Homo sapiens G protein-coupled receptor 112 (GPR112), mRNA.	564					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(2)|breast(13)|central_nervous_system(2)|cervix(3)|endometrium(17)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(33)|lung(97)|ovary(5)|pancreas(2)|prostate(4)|skin(10)|upper_aerodigestive_tract(1)|urinary_tract(2)	199	Acute lymphoblastic leukemia(192;0.000127)					AACATCCTTTTCATTTACTGG	0.418000														46			12		0	0	0.00136819	0	0
FAM134C	162427	broad.mit.edu	37	17	40761321	40761321	+	Missense_Mutation	SNP	G	C	C			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr17:40761321G>C	uc002ial.2	-	0	125	c.22C>G	c.(22-24)Ccc>Gcc	p.P8A	TUBG1_uc002ian.3_5'Flank|FAM134C_uc010wgq.1_5'UTR|FAM134C_uc002iam.1_5'UTR|FAM134C_uc010cyk.1_Intron	NM_178126	NP_835227	Q86VR2	F134C_HUMAN	Homo sapiens family with sequence similarity 134, member C (FAM134C), transcript variant 1, mRNA.	8						integral to membrane				endometrium(1)|large_intestine(3)|liver(1)|lung(2)|ovary(1)|prostate(1)|upper_aerodigestive_tract(2)	11		Breast(137;0.00116)		BRCA - Breast invasive adenocarcinoma(366;0.134)		GGGGTCGTGGGAACCCCTTCG	0.687000														33			13		0	0	0.000219431	0	0
SERPINA13	388007	broad.mit.edu	37	14	95111314	95111314	+	Missense_Mutation	SNP	C	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr14:95111314C>A	uc001ydt.3	+	3	1134	c.1046C>A	c.(1045-1047)cCc>cAc	p.P349H						Homo sapiens serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 13 (pseudogene) (SERPINA13), non-coding RNA.											endometrium(1)|large_intestine(1)|lung(9)|skin(1)	12						TTCCACTTCCCCAAATTTTCC	0.522000														18			19		7.45023e-12	4.89231e-11	0.00152264	1	0
AIRE	326	broad.mit.edu	37	21	45709924	45709924	+	Silent	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr21:45709924C>T	uc002zei.2	+	6	979	c.852C>T	c.(850-852)gcC>gcT	p.A284A	AIRE_uc010gpq.2_5'Flank|AIRE_uc002zej.2_5'Flank|AIRE_uc010gpr.2_5'Flank	NM_000383	NP_000374	O43918	AIRE_HUMAN	Homo sapiens autoimmune regulator (AIRE), transcript variant AIRE-1, mRNA.	284					positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	chromatin binding|histone binding|transcription regulatory region DNA binding|translation regulator activity|zinc ion binding			breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(7)|skin(2)|urinary_tract(1)	14				Colorectal(79;0.0806)		CCCCTCTGGCCCTCCCCAGTG	0.687000									Autoimmune PolyEndocrinopathy Candidiasis Ectodermal Dystrophy					16			7		0	0	0.000442599	0	0
SC5DL	6309	broad.mit.edu	37	11	121178150	121178150	+	Missense_Mutation	SNP	C	T	T	rs118099079	by1000genomes	TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr11:121178150C>T	uc001pxu.3	+	4	977	c.829C>T	c.(829-831)Cgc>Tgc	p.R277C	SC5DL_uc001pxt.3_3'UTR|SC5DL_uc001pxv.3_Missense_Mutation_p.R277C	NM_006918	NP_008849	O75845	SC5D_HUMAN	Homo sapiens sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like (SC5DL), transcript variant 1, mRNA.	277				PQILQPFINGSAHHTDHHMFFDYNYGQYFTLWDRIGGSFKN PSSFEGKGPLSYVKEMTEGKRSSHSGNGCKNEKLFNGEFTK TE -> RMKNYSMESLQRLNRLLPSYS (in Ref. 1; BAA18970).	fatty acid biosynthetic process	endoplasmic reticulum membrane|integral to membrane	C-5 sterol desaturase activity|iron ion binding|lathosterol oxidase activity			endometrium(1)|kidney(1)|large_intestine(4)|lung(4)|ovary(1)|pancreas(1)|skin(1)	13		Breast(109;0.00328)|Medulloblastoma(222;0.0425)|all_neural(223;0.112)	OV - Ovarian serous cystadenocarcinoma(1;0.0334)	BRCA - Breast invasive adenocarcinoma(274;5.1e-06)|OV - Ovarian serous cystadenocarcinoma(223;0.144)		AGAGGGAAAGCGCAGCAGCCA	0.413000														23			11		0	0	0.000978159	0	0
ADAM20	8748	broad.mit.edu	37	14	70991372	70991372	+	Missense_Mutation	SNP	G	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr14:70991372G>T	uc021rvs.1	-	0	253	c.253C>A	c.(253-255)Cag>Aag	p.Q85K	ADAM20_uc001xme.3_Missense_Mutation_p.Q85K	NM_003814	NP_003805	O43506	ADA20_HUMAN	Homo sapiens ADAM metallopeptidase domain 20 (ADAM20), mRNA.	35					proteolysis|single fertilization	integral to membrane	metalloendopeptidase activity|zinc ion binding			autonomic_ganglia(1)|breast(2)|endometrium(2)|kidney(1)|large_intestine(3)|lung(15)|prostate(1)|skin(2)	27			KIRC - Kidney renal clear cell carcinoma(12;0.133)|Kidney(31;0.188)	all cancers(60;0.00294)|BRCA - Breast invasive adenocarcinoma(234;0.00668)|OV - Ovarian serous cystadenocarcinoma(108;0.0344)		GTGAAATACTGGGAGGGCCTG	0.557000														11			13		2.27111e-07	1.35578e-06	0.00136819	1	0
KRT10	3858	broad.mit.edu	37	17	38976882	38976882	+	Missense_Mutation	SNP	C	T	T			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr17:38976882C>T	uc002hvi.3	-	2	774	c.748G>A	c.(748-750)Gct>Act	p.A250T	TMEM99_uc021txc.1_Intron|TMEM99_uc002hvj.1_Intron|TMEM99_uc021txd.1_Intron	NM_000421	NP_000412	P13645	K1C10_HUMAN	Homo sapiens keratin 10 (KRT10), mRNA.	250	Coil 1B.|Gly-rich.|Rod.				epidermis development		protein binding|structural constituent of epidermis			NS(2)|kidney(1)|large_intestine(3)|lung(4)|prostate(1)	11		Breast(137;0.000301)				TTGATGTCAGCCTCCACGCTC	0.507000														31			23		0	0	0.000375601	0	0
BRAF	673	broad.mit.edu	37	7	140453136	140453136	+	Missense_Mutation	SNP	A	T	T	rs121913377		TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr7:140453136A>T	uc003vwc.4	-	14	1860	c.1799T>A	c.(1798-1800)gTg>gAg	p.V600E		NM_004333	NP_004324	P15056	BRAF_HUMAN	Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF), mRNA.	600	Protein kinase.		V -> D (in a melanoma cell line; requires 2 nucleotide substitutions).|V -> E (in sarcoma, colorectal adenocarcinoma, metastatic melanoma, ovarian serous carcinoma, pilocytic astrocytoma; somatic mutation; most common mutation; constitutive and elevated kinase activity; efficiently induces cell transformation; suppression of mutation in melanoma causes growth arrest and promotes apoptosis).		activation of MAPKK activity|anti-apoptosis|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of peptidyl-serine phosphorylation|small GTPase mediated signal transduction|synaptic transmission	cytosol|nucleus|plasma membrane	ATP binding|metal ion binding	p.V600E(41204)|p.V600K(615)|p.V600?(377)|p.V600R(99)|p.V600D(40)|p.V600_K601>E(30)|p.V600L(28)|p.V600A(24)|p.V600G(22)|p.V600M(22)|p.A598_T599insV(7)|p.T599_V600insT(7)|p.T599I(5)|p.V600Q(4)|p.T599_R603>I(4)|p.T599_V600insTT(3)|p.T599_V600insDFGLAT(2)|p.T599_V600>IAL(2)|p.V600_S605>EK(2)|p.T599T(2)|p.V600_S605>DV(2)|p.V600_S605>D(2)|p.V600_W604del(1)|p.V600V(1)|p.T599_V600insV(1)|p.V600>DLAT(1)|p.D594_T599del(1)	SLC45A3/BRAF(2)|AGTRAP/BRAF(2)|FAM131B_ENST00000443739/BRAF(7)|AKAP9_ENST00000356239/BRAF(10)|KIAA1549/BRAF(703)|FCHSD1/BRAF(2)	NS(588)|adrenal_gland(3)|autonomic_ganglia(3)|biliary_tract(29)|bone(7)|breast(21)|central_nervous_system(99)|cervix(6)|endometrium(33)|eye(72)|gastrointestinal_tract_(site_indeterminate)(2)|genital_tract(4)|haematopoietic_and_lymphoid_tissue(436)|kidney(3)|large_intestine(6953)|liver(17)|lung(192)|oesophagus(4)|ovary(275)|pancreas(15)|pituitary(1)|prostate(25)|salivary_gland(1)|skin(6285)|small_intestine(12)|soft_tissue(40)|stomach(11)|testis(7)|thyroid(12220)|upper_aerodigestive_tract(13)|urinary_tract(3)	27380	Melanoma(164;0.00956)				Sorafenib(DB00398)	TCGAGATTTCACTGTAGCTAG	0.368000	V600D(K029AX_SKIN)|V600D(WM115_SKIN)|V600D(WM2664_SKIN)|V600E(8505C_THYROID)|V600E(A101D_SKIN)|V600E(A2058_SKIN)|V600E(A375_SKIN)|V600E(A673_BONE)|V600E(AM38_CENTRAL_NERVOUS_SYSTEM)|V600E(BCPAP_THYROID)|V600E(BHT101_THYROID)|V600E(BT474_BREAST)|V600E(C32_SKIN)|V600E(CL34_LARGE_INTESTINE)|V600E(COLO205_LARGE_INTESTINE)|V600E(COLO679_SKIN)|V600E(COLO741_SKIN)|V600E(COLO783_SKIN)|V600E(COLO800_SKIN)|V600E(COLO818_SKIN)|V600E(COLO829_SKIN)|V600E(COLO849_SKIN)|V600E(DBTRG05MG_CENTRAL_NERVOUS_SYSTEM)|V600E(DU4475_BREAST)|V600E(ES2_OVARY)|V600E(G361_SKIN)|V600E(GCT_SOFT_TISSUE)|V600E(HS294T_SKIN)|V600E(HS695T_SKIN)|V600E(HS939T_SKIN)|V600E(IGR1_SKIN)|V600E(IGR37_SKIN)|V600E(IGR39_SKIN)|V600E(K029AX_SKIN)|V600E(KG1C_CENTRAL_NERVOUS_SYSTEM)|V600E(LOXIMVI_SKIN)|V600E(MALME3M_SKIN)|V600E(MELHO_SKIN)|V600E(OUMS23_LARGE_INTESTINE)|V600E(RKO_LARGE_INTESTINE)|V600E(RPMI7951_SKIN)|V600E(RVH421_SKIN)|V600E(SH4_SKIN)|V600E(SIGM5_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|V600E(SKHEP1_LIVER)|V600E(SKMEL24_SKIN)|V600E(SKMEL28_SKIN)|V600E(SKMEL5_SKIN)|V600E(SW1417_LARGE_INTESTINE)|V600E(UACC257_SKIN)|V600E(UACC62_SKIN)|V600E(WM793_SKIN)|V600E(WM88_SKIN)|V600E(WM983B_SKIN)	61	"""Mis, T, O"""	"""AKAP9, KIAA1549"""	"""melanoma, colorectal, papillary thyroid, borderline ov, Non small-cell lung cancer (NSCLC), cholangiocarcinoma, pilocytic astrocytoma"""		Cardio-facio-cutaneous syndrome		Cardiofaciocutaneous syndrome					10			32		0	0	0.000953801	0	0
ANKRD30BP2	149992	broad.mit.edu	37	21	14439208	14439208	+	RNA	SNP	A	G	G			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr21:14439208A>G	uc002yja.4	+	9		c.2726A>G								Homo sapiens ankyrin repeat domain 30B pseudogene 2 (ANKRD30BP2), non-coding RNA.																		AAGAGAAGAAATGCCAATATA	0.299000														23			8		0	0	0.000157383	0	0
C5orf38	153571	broad.mit.edu	37	5	2752737	2752742	+	In_Frame_Del	DEL	TTTGTG	-	-			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr5:2752737_2752742delTTTGTG	uc003jdc.3	+	1	319_324	c.202_207delTTTGTG	c.(202-207)tttgtgdel	p.FV68del	C5orf38_uc011cmg.2_In_Frame_Del_p.FV68del|C5orf38_uc011cmh.2_Intron|C5orf38_uc011cmi.2_Intron|C5orf38_uc011cmj.2_Intron	NM_178569	NP_848664	Q86SI9	CEI_HUMAN	Homo sapiens chromosome 5 open reading frame 38 (C5orf38), mRNA.	68						extracellular region				endometrium(2)|large_intestine(1)|lung(1)	4				GBM - Glioblastoma multiforme(108;0.205)		CTCTTTCAGATTTGTGTTGTCAAAAC	0.490													---	87	---	---	24	---					
C7orf65	401335	broad.mit.edu	37	7	47698645	47698646	+	Frame_Shift_Ins	INS	-	A	A			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr7:47698645_47698646insA	uc010kyp.1	+	2	310_311	c.275_276insA	c.(274-276)ggafs	p.G92fs		NM_001123065	NP_001116537	Q6ZTY9	CG065_HUMAN	Homo sapiens chromosome 7 open reading frame 65 (C7orf65), mRNA.	92										endometrium(1)|lung(2)	3						AATTCATGTGGAATCACCCTAG	0.515													---	58	---	---	34	---					
ARFGEF1	10565	broad.mit.edu	37	8	68152466	68152468	+	In_Frame_Del	DEL	AGT	-	-			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr8:68152466_68152468delAGT	uc003xxo.2	-	19	3298_3300	c.2908_2910delACT	c.(2908-2910)actdel	p.T970del	ARFGEF1_uc003xxl.1_In_Frame_Del_p.T424del|ARFGEF1_uc003xxn.2_5'UTR	NM_006421	NP_006412	Q9Y6D6	BIG1_HUMAN	Homo sapiens ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) (ARFGEF1), mRNA.	970					exocytosis|regulation of ARF protein signal transduction	cytoplasm	ARF guanyl-nucleotide exchange factor activity|myosin binding			breast(1)|endometrium(14)|kidney(4)|large_intestine(17)|lung(20)|ovary(4)|skin(1)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	65	Breast(64;0.214)	Lung NSC(129;0.0908)|all_lung(136;0.152)	Epithelial(68;0.0043)|OV - Ovarian serous cystadenocarcinoma(28;0.00578)|all cancers(69;0.0173)|BRCA - Breast invasive adenocarcinoma(89;0.206)			AGGCTACTTCAGTATCATCACAA	0.360													---	78	---	---	25	---					
DLG4	1742	broad.mit.edu	37	17	7096904	7096917	+	Splice_Site	DEL	CTGCAGAGAGAGCC	-	-			TCGA-FS-A1YX-06A-11D-A197-08	TCGA-FS-A1YX-10A-01D-A199-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	3b8e4b31-301c-4f19-8b9f-3995bbddb4fa	ab4c890d-d4cd-4fe8-a7d5-244d7c70e448	g.chr17:7096904_7096917delCTGCAGAGAGAGCC	uc010vtn.2	-	15	1672	c.1412_splice	c.e15-1	p.V471_splice	DLG4_uc010vtm.2_Splice_Site|DLG4_uc010cly.3_Splice_Site_p.V528_splice|DLG4_uc002get.4_Splice_Site_p.V574_splice|DLG4_uc010vto.2_Splice_Site_p.V571_splice	NM_001128827	NP_001122299	P78352	DLG4_HUMAN	Homo sapiens discs, large homolog 4 (Drosophila) (DLG4), transcript variant 2, mRNA.	531	SH3.				axon guidance|learning|protein complex assembly|protein localization to synapse|signal transduction|synaptic transmission	cell junction|cortical cytoskeleton|endocytic vesicle membrane|neuron spine|postsynaptic density|postsynaptic membrane|synaptosome	protein C-terminus binding|protein binding			breast(1)|cervix(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(8)|ovary(2)	18						GCATAGTGCACTGCAGAGAGAGCCTGGCTTAGGC	0.612													---	11	---	---	5	---