Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
HERC1	0	genome.wustl.edu	37	15	63928318	63928318	+	Missense_Mutation	SNP	T	T	C			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	15	63928318	63928318	T	C	SNP	HERC1	ENST00000443617	human	ensembl	74_37	-1	known	missense	c.12256	p.T4086A	1.000	pfam_Reg_chr_condens,superfamily_RCC1/BLIP-II,pfscan_Reg_chr_condens	pfam_Reg_chr_condens,pfam_HECT,pfam_WD40_repeat,pfam_SPRY_rcpt,superfamily_RCC1/BLIP-II,superfamily_HECT,superfamily_WD40_repeat_dom,superfamily_ConA-like_lec_gl_sf,superfamily_UBA-like,superfamily_ARM-type_fold,smart_SPla/RYanodine_receptor_subgr,smart_WD40_repeat,smart_HECT,pfscan_B30.2/SPRY,pfscan_HECT,pfscan_Reg_chr_condens,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_Reg_chr_condens	-	no_errors	HERC1	HGNC	ENSG00000103657	tier1	-	-	67	0	0.00	34	37	52.11	97	0	0.00	65	59	47.58
TRDN	0	genome.wustl.edu	37	6	123869712	123869712	+	Missense_Mutation	SNP	C	C	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	6	123869712	123869712	C	T	SNP	TRDN	ENST00000398178	human	ensembl	74_37	-1	known	missense	c.278	p.R93H	0.983	pfam_Asp-B-hydro/Triadin_dom	pfam_Asp-B-hydro/Triadin_dom	-	no_errors	TRDN	HGNC	ENSG00000186439	tier1	-	-	51	0	0.00	30	10	25.00	104	0	0.00	63	17	20.73
ZEB2-AS1	0	genome.wustl.edu	37	2	145277515	145277515	+	R	SNP	C	C	G			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	2	145277515	145277515	C	G	SNP	ZEB2-AS1	ENST00000421083	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	ZEB2-AS1	HGNC	ENSG00000238057	tier1	-	-	81	0	0.00	34	21	38.18	143	0	0.00	56	56	50.00
POU2F2	0	genome.wustl.edu	37	19	42626729	42626729	+	Splice_Site	SNP	C	C	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	19	42626729	42626729	C	T	SNP	POU2F2	ENST00000342301	human	ensembl	74_37	-1	known	splice_site	c.29-1	e2-1	1.000	-	-	-	no_errors	POU2F2	HGNC	ENSG00000028277	tier1	-	-	103	0	0.00	66	24	26.67	82	0	0.00	45	19	29.69
TTLL11	0	genome.wustl.edu	37	9	124801570	124801570	+	Silent	SNP	A	A	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	9	124801570	124801570	A	T	SNP	TTLL11	ENST00000321582	human	ensembl	74_37	-1	known	silent	c.810	p.G270	1.000	pfam_TTL/TTLL_fam	pfam_TTL/TTLL_fam	-	no_errors	TTLL11	HGNC	ENSG00000175764	tier1	-	-	97	0	0.00	62	8	11.43	141	0	0.00	96	15	13.51
ATG16L1	0	genome.wustl.edu	37	2	234173536	234173536	+	Splice_Site	SNP	A	A	G			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	2	234173536	234173536	A	G	SNP	ATG16L1	ENST00000392017	human	ensembl	74_37	+1	known	splice_site	c.390-2	e5-2	1.000	-	-	-	no_errors	ATG16L1	HGNC	ENSG00000085978	tier1	-	-	54	0	0.00	26	14	35.00	84	0	0.00	29	28	49.12
COPE	0	genome.wustl.edu	37	19	19021743	19021748	+	R	DEL	CCCGCG	CCCGCG	-			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	CCCGCG	CCCGCG	CCCGCG	-	CCCGCG	CCCGCG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	19	19021743	19021748	CCCGCG	-	DEL	COPE	ENST00000597646	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.003:0.001:0.002:0.002:0.015:0.028	-	-	-	no_errors	COPE	HGNC	ENSG00000105669	tier1			100	0	0.00	32	35	52.24	100	0	0.00	32	35	52.24
DBN1	0	genome.wustl.edu	37	5	176885489	176885490	+	Frame_Shift_Ins	INS	-	-	C			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	-	-	-	C	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	5	176885489	176885490	-	C	INS	DBN1	ENST00000292385	human	ensembl	74_37	-1	known	frame_shift_ins	c.1352_1351	p.A451fs	0.212:0.018	NULL	pfam_Actin-bd_cofilin/tropomyosin,smart_Actin-bd_cofilin/tropomyosin	-	no_errors	DBN1	HGNC	ENSG00000113758	tier1			68	0	0.00	22	15	40.54	88	0	0.00	29	31	51.67
DTX1	0	genome.wustl.edu	37	12	113532615	113532615	+	Nonsense_Mutation	SNP	C	C	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	12	113532615	113532615	C	T	SNP	DTX1	ENST00000257600	human	ensembl	74_37	+1	known	nonsense	c.1249	p.R417*	1.000	smart_Znf_RING,pfscan_Znf_RING	pfam_WWE-dom,smart_WWE-dom_subgr,smart_Znf_RING,pfscan_WWE-dom,pfscan_Znf_RING	-	no_errors	DTX1	HGNC	ENSG00000135144	tier1	-	-	33	0	0.00	31	4	11.43	5	0	0.00	8	0	0.00
LOC440905	0	genome.wustl.edu	37	2	130807905	130807905	+	R	SNP	G	G	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	2	130807905	130807905	G	T	SNP	LOC440905	ENST00000325390	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.233	-	-	-	no_errors	AC018865.8	Clone_based_vega_gene	ENSG00000180178	tier1	rs201541587	-	32	0	0.00	16	4	20.00	6	0	0.00	9	0	0.00
RPL13A	0	genome.wustl.edu	37	19	49993810	49993810	+	Missense_Mutation	SNP	G	G	A			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	19	49993810	49993810	G	A	SNP	RPL13A	ENST00000391857	human	ensembl	74_37	+1	known	missense	c.233	p.R78H	1.000	pfam_Ribosomal_L13,superfamily_Ribosomal_L13_dom,tigrfam_Ribosomal_L13_euk/arc	pfam_Ribosomal_L13,superfamily_Ribosomal_L13_dom,tigrfam_Ribosomal_L13_euk/arc	-	no_errors	RPL13A	HGNC	ENSG00000142541	tier1	-	-	50	0	0.00	46	4	8.00	6	0	0.00	2	0	0.00
STAB1	0	genome.wustl.edu	37	3	52540712	52540712	+	Missense_Mutation	SNP	G	G	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	3	52540712	52540712	G	T	SNP	STAB1	ENST00000321725	human	ensembl	74_37	+1	known	missense	c.1835	p.R612L	1.000	pfam_FAS1_domain,superfamily_FAS1_domain,smart_FAS1_domain,pfscan_FAS1_domain	pfam_FAS1_domain,pfam_Link,superfamily_C-type_lectin_fold,superfamily_FAS1_domain,smart_EG-like_dom,smart_EGF_laminin,smart_FAS1_domain,smart_EGF-like_Ca-bd_dom,smart_Link,pfscan_EG-like_dom,pfscan_FAS1_domain,pfscan_Link	-	no_errors	STAB1	HGNC	ENSG00000010327	tier1	-	-	30	0	0.00	8	4	33.33	6	0	0.00	5	0	0.00
ENSG00000221280	0	genome.wustl.edu	37	12	118604652	118604653	+	R	INS	-	-	ACAC			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	12	118604652	118604653	-	ACAC	INS	ENSG00000221280	ENST00000408353	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.002:0.000	-	-	-	no_errors	AC026366.1	Clone_based_ensembl_gene	ENSG00000221280	tier1			19	0	0.00	8	3	27.27	0	0	0.00	0	0	0.00
NUTM2E	0	genome.wustl.edu	37	10	81606700	81606700	+	Silent	SNP	C	C	T			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	10	81606700	81606700	C	T	SNP	NUTM2E	ENST00000429984	human	ensembl	74_37	+1	known	silent	c.1197	p.Y399	0.069	NULL	NULL	-	no_errors	NUTM2E	HGNC	ENSG00000228570	tier1	-	-	17	0	0.00	3	5	62.50	3	0	0.00	1	1	50.00
ENSG00000267075	0	genome.wustl.edu	37	17	20451293	20451293	+	R	SNP	A	A	G			TCGA-X6-A8C7-01A-11D-A36J-09	TCGA-X6-A8C7-10A-01D-A36M-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	b052af04-ea5e-4acc-8fd1-1b647128a35b	ef4fb3ba-651c-48b8-b2c6-5e957c154b14	17	20451293	20451293	A	G	SNP	ENSG00000267075	ENST00000591705	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.033	-	-	-	no_errors	RP11-434D2.3	Clone_based_vega_gene	ENSG00000267075	tier1	-	-	24	0	0.00	15	5	25.00	2	0	0.00	9	2	18.18