Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ROR2	0	genome.wustl.edu	37	9	94484841	94484841	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	9	94484841	94484841	C	T	SNP	ROR2	ENST00000375715	human	ensembl	74_37	-1	putative	missense	c.1942	p.G648R	0.000	NULL	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Kringle,pfam_Frizzled_dom,superfamily_Kinase-like_dom,superfamily_Kringle-like,superfamily_Frizzled_dom,smart_Kringle,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Frizzled_dom,pfscan_Kringle,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	ROR2	HGNC	ENSG00000169071	tier1	-	-	21	0	0.00	21	6	22.22	97	0	0.00	131	23	14.94
MAGED1	0	genome.wustl.edu	37	X	51638173	51638173	+	Missense_Mutation	SNP	G	G	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	X	51638173	51638173	G	A	SNP	MAGED1	ENST00000375695	human	ensembl	74_37	+1	known	missense	c.238	p.A80T	0.950	NULL	pfam_MAGE,pfscan_MAGE	-	no_errors	MAGED1	HGNC	ENSG00000179222	tier1	-	-	61	0	0.00	23	30	56.60	68	0	0.00	70	22	23.91
UBXN4	0	genome.wustl.edu	37	2	136530072	136530072	+	Missense_Mutation	SNP	A	A	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	2	136530072	136530072	A	G	SNP	UBXN4	ENST00000272638	human	ensembl	74_37	+1	known	missense	c.905	p.Q302R	1.000	NULL	pfam_UBX,superfamily_Thioredoxin-like_fold,smart_UBX,pfscan_UBX	-	no_errors	UBXN4	HGNC	ENSG00000144224	tier1	-	-	61	0	0.00	57	41	41.84	79	0	0.00	117	16	12.03
LIN37	0	genome.wustl.edu	37	19	36244131	36244131	+	Missense_Mutation	SNP	C	C	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	19	36244131	36244131	C	G	SNP	LIN37	ENST00000301159	human	ensembl	74_37	+1	known	missense	c.421	p.P141A	0.901	NULL	NULL	-	no_errors	LIN37	HGNC	ENSG00000267796	tier1	-	-	58	0	0.00	68	22	24.44	9	0	0.00	17	8	32.00
LOC440700	0	genome.wustl.edu	37	1	165677941	165677941	+	R	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	165677941	165677941	C	T	SNP	LOC440700	ENST00000400982	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.013	-	-	-	no_errors	RP11-466F5.6	Clone_based_vega_gene	ENSG00000215838	tier1	-	-	38	0	0.00	2	10	83.33	54	0	0.00	65	20	23.53
FLG2	0	genome.wustl.edu	37	1	152328366	152328366	+	Silent	SNP	G	G	C			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	152328366	152328366	G	C	SNP	FLG2	ENST00000388718	human	ensembl	74_37	-1	known	silent	c.1896	p.G632	0.000	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom,prints_Filaggrin	-	no_errors	FLG2	HGNC	ENSG00000143520	tier1	-	-	107	1	0.92	61	40	39.22	52	0	0.00	95	24	20.00
ARRDC1	0	genome.wustl.edu	37	9	140507315	140507315	+	R	SNP	T	T	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	9	140507315	140507315	T	A	SNP	ARRDC1	ENST00000491911	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.300	-	-	-	no_errors	ARRDC1	HGNC	ENSG00000197070	tier1	-	-	47	0	0.00	16	6	27.27	15	0	0.00	27	4	12.90
SASH1	0	genome.wustl.edu	37	6	148846428	148846428	+	Missense_Mutation	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	6	148846428	148846428	G	T	SNP	SASH1	ENST00000367467	human	ensembl	74_37	+1	known	missense	c.1211	p.R404I	1.000	pfam_rSAM/SH3_domain-containing	pfam_rSAM/SH3_domain-containing,pfam_SAM_2,pfam_SAM_type1,pfam_SH3_2,superfamily_SAM/pointed,superfamily_SH3_domain,smart_SH3_domain,smart_SAM,pfscan_SAM	-	no_errors	SASH1	HGNC	ENSG00000111961	tier1	-	-	50	0	0.00	31	43	58.11	124	0	0.00	128	38	22.89
ZCCHC12	0	genome.wustl.edu	37	X	117960020	117960020	+	Silent	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	X	117960020	117960020	C	T	SNP	ZCCHC12	ENST00000310164	human	ensembl	74_37	+1	known	silent	c.813	p.D271	0.946	NULL	superfamily_Znf_CCHC	-	no_errors	ZCCHC12	HGNC	ENSG00000174460	tier1	-	-	35	0	0.00	5	11	68.75	28	0	0.00	40	13	24.53
LRIT2	0	genome.wustl.edu	37	10	85982349	85982349	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	10	85982349	85982349	C	T	SNP	LRIT2	ENST00000538192	human	ensembl	74_37	-1	known	missense	c.1010	p.C337Y	0.998	pfam_Ig_I-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Leu-rich_rpt,superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	LRIT2	HGNC	ENSG00000204033	tier1	-	-	37	0	0.00	10	15	60.00	102	0	0.00	121	29	19.21
AHK2	0	genome.wustl.edu	37	14	105413459	105413459	+	Missense_Mutation	SNP	A	A	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	14	105413459	105413459	A	G	SNP	AHK2	ENST00000333244	human	ensembl	74_37	-1	known	missense	c.8329	p.S2777P	0.466	NULL	superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	AHK2	HGNC	ENSG00000185567	tier1	-	-	97	0	0.00	67	60	47.24	31	0	0.00	22	4	15.38
ADCY8	0	genome.wustl.edu	37	8	132051899	132051899	+	Silent	SNP	G	G	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	8	132051899	132051899	G	A	SNP	ADCY8	ENST00000286355	human	ensembl	74_37	-1	known	silent	c.681	p.C227	0.998	NULL	pfam_A/G_cyclase,pfam_Adenylate_cyclase-like,superfamily_A/G_cyclase,smart_A/G_cyclase,pfscan_A/G_cyclase	-	no_errors	ADCY8	HGNC	ENSG00000155897	tier1	-	-	24	0	0.00	10	12	54.55	51	0	0.00	85	28	24.78
TP53	0	genome.wustl.edu	37	17	7578393	7578393	+	Missense_Mutation	SNP	A	A	C			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	17	7578393	7578393	A	C	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.537	p.H179Q	0.699	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	39	0	0.00	8	7	46.67	67	0	0.00	55	13	19.12
FAM210B	0	genome.wustl.edu	37	20	54941148	54941148	+	Missense_Mutation	SNP	C	C	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	20	54941148	54941148	C	G	SNP	FAM210B	ENST00000371384	human	ensembl	74_37	+1	known	missense	c.384	p.I128M	0.995	pfam_DUF1279	pfam_DUF1279	-	no_errors	FAM210B	HGNC	ENSG00000124098	tier1	-	-	21	0	0.00	30	11	26.83	45	0	0.00	69	11	13.75
BMP6	0	genome.wustl.edu	37	6	7727534	7727534	+	Missense_Mutation	SNP	C	C	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	6	7727534	7727534	C	A	SNP	BMP6	ENST00000283147	human	ensembl	74_37	+1	known	missense	c.346	p.Q116K	0.341	pfam_TGF-b_N	pfam_TGF-b_N,pfam_TGF-b_C,smart_TGF-b_C	-	no_errors	BMP6	HGNC	ENSG00000153162	tier1	-	-	10	0	0.00	7	4	36.36	8	0	0.00	1	3	75.00
CDH26	0	genome.wustl.edu	37	20	58577889	58577889	+	Missense_Mutation	SNP	C	C	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	20	58577889	58577889	C	G	SNP	CDH26	ENST00000348616	human	ensembl	74_37	+1	known	missense	c.2188	p.P730A	0.008	NULL	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH26	HGNC	ENSG00000124215	tier1	-	-	78	0	0.00	66	16	19.28	109	0	0.00	143	12	7.74
MYL1	0	genome.wustl.edu	37	2	211179643	211179643	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	2	211179643	211179643	C	T	SNP	MYL1	ENST00000352451	human	ensembl	74_37	-1	known	missense	c.124	p.A42T	0.993	NULL	smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	MYL1	HGNC	ENSG00000168530	tier1	-	-	61	0	0.00	59	7	10.61	86	0	0.00	99	10	9.17
NCKIPSD	0	genome.wustl.edu	37	3	48701489	48701489	+	Missense_Mutation	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	3	48701489	48701489	G	T	SNP	NCKIPSD	ENST00000341520	human	ensembl	74_37	-1	known	missense	c.2044	p.P682T	0.098	NULL	pfam_DUF2013,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,smart_SH3_domain,pfscan_SH3_domain	-	no_errors	NCKIPSD	HGNC	ENSG00000213672	tier1	-	-	179	0	0.00	119	26	17.93	28	0	0.00	89	5	5.26
MYADML	0	genome.wustl.edu	37	2	33952141	33952141	+	R	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	2	33952141	33952141	C	T	SNP	MYADML	ENST00000474610	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	MYADML	HGNC	ENSG00000239649	tier1	-	-	61	0	0.00	49	20	28.99	148	0	0.00	174	12	6.45
FILIP1	0	genome.wustl.edu	37	6	76023331	76023331	+	Silent	SNP	A	A	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	6	76023331	76023331	A	G	SNP	FILIP1	ENST00000237172	human	ensembl	74_37	-1	known	silent	c.2217	p.D739	0.956	NULL	pfam_Cortactin-binding_p2_N,prints_Tropomyosin	-	no_errors	FILIP1	HGNC	ENSG00000118407	tier1	-	-	24	0	0.00	9	10	52.63	88	0	0.00	79	6	7.06
CHD5	0	genome.wustl.edu	37	1	6206323	6206323	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	6206323	6206323	C	T	SNP	CHD5	ENST00000262450	human	ensembl	74_37	-1	known	missense	c.1751	p.R584H	1.000	superfamily_Chromodomain-like	pfam_CHD_C2,pfam_SNF2_N,pfam_DUF1086,pfam_CHD_N,pfam_DUF1087,pfam_Znf_PHD-finger,pfam_Chromo_domain,pfam_Helicase_C,pfam_Helicase/UvrB_dom,superfamily_P-loop_NTPase,superfamily_Chromodomain-like,superfamily_Znf_FYVE_PHD,superfamily_HMG_box_dom,smart_Znf_PHD,smart_Chromo_domain/shadow,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Znf_PHD-finger,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_Chromo_domain/shadow	-	no_errors	CHD5	HGNC	ENSG00000116254	tier1	rs141210110	-	35	0	0.00	17	9	34.62	63	0	0.00	96	7	6.80
CPS1	0	genome.wustl.edu	37	2	211540493	211540493	+	Missense_Mutation	SNP	C	C	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	2	211540493	211540493	C	A	SNP	CPS1	ENST00000430249	human	ensembl	74_37	+1	known	missense	c.4221	p.N1407K	1.000	pfam_MGS-like_dom,superfamily_MGS-like_dom,smart_MGS-like_dom,tigrfam_CarbamoylP_synth_lsu	pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_CarbamoylP_synth_ssu_N,pfam_CarbamoylP_synth_lsu_oligo,pfam_GATASE,pfam_CarbamoylP_synth_lsu_N,pfam_MGS-like_dom,pfam_ATP-grasp_carboxylate-amine,pfam_Dala_Dala_lig_C,superfamily_CarbamoylP_synth_lsu_oligo,superfamily_CarbamoylP_synth_ssu_N,superfamily_PreATP-grasp_dom,superfamily_MGS-like_dom,smart_MGS-like_dom,pfscan_ATP-grasp,prints_CbamoylP_synth_lsu_CPSase_dom,tigrfam_CarbamoylP_synth_lsu,tigrfam_CarbamoylP_synth_ssu	-	no_errors	CPS1	HGNC	ENSG00000021826	tier1	-	-	43	0	0.00	39	9	18.75	61	0	0.00	101	9	8.18
GINS1	0	genome.wustl.edu	37	20	25422336	25422336	+	Splice_Site	SNP	A	A	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	20	25422336	25422336	A	G	SNP	GINS1	ENST00000262460	human	ensembl	74_37	+1	known	splice_site	c.448-2	e6-2	1.000	-	-	-	no_errors	GINS1	HGNC	ENSG00000101003	tier1	-	-	49	0	0.00	45	13	22.41	83	0	0.00	74	4	5.13
TRPM6	0	genome.wustl.edu	37	9	77502760	77502760	+	Missense_Mutation	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	9	77502760	77502760	G	T	SNP	TRPM6	ENST00000451710	human	ensembl	74_37	-1	known	missense	c.13	p.P5T	0.000	NULL	pfam_MHCK_EF2_kinase,pfam_Ion_trans_dom,superfamily_Kinase-like_dom,smart_MHCK_EF2_kinase,pfscan_MHCK_EF2_kinase	-	no_errors	TRPM6	HGNC	ENSG00000119121	tier1	-	-	34	0	0.00	22	14	38.89	74	1	1.33	139	15	9.74
NPFFR2	0	genome.wustl.edu	37	4	73013005	73013005	+	Missense_Mutation	SNP	T	T	C			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	4	73013005	73013005	T	C	SNP	NPFFR2	ENST00000308744	human	ensembl	74_37	+1	known	missense	c.1045	p.F349L	0.998	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_NPFF_rcpt_2,prints_NPFF_rcpt,prints_GPCR_Rhodpsn,prints_NPY_rcpt	-	no_errors	NPFFR2	HGNC	ENSG00000056291	tier1	-	-	54	0	0.00	42	17	28.81	91	1	1.09	112	6	5.08
SYNE4	0	genome.wustl.edu	37	19	36497392	36497392	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	19	36497392	36497392	C	T	SNP	SYNE4	ENST00000324444	human	ensembl	74_37	-1	known	missense	c.800	p.R267Q	0.030	NULL	pfam_KASH,pfscan_KASH	-	no_errors	SYNE4	HGNC	ENSG00000181392	tier1	rs200616477	-	56	0	0.00	63	13	17.11	33	0	0.00	83	7	7.78
RGS21	0	genome.wustl.edu	37	1	192316509	192316522	+	Frame_Shift_Del	DEL	AGCCAACCAAGGTA	AGCCAACCAAGGTA	-			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	AGCCAACCAAGGTA	AGCCAACCAAGGTA	AGCCAACCAAGGTA	-	AGCCAACCAAGGTA	AGCCAACCAAGGTA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	192316509	192316522	AGCCAACCAAGGTA	-	DEL	RGS21	ENST00000417209	human	ensembl	74_37	+1	known	frame_shift_del	c.78_88	p.L26fs	1.000:1.000:1.000:0.991:0.990:0.968:0.645:0.950:1.000:1.000:1.000	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	pfam_RGS_dom,superfamily_Regulat_G_prot_signal_superfam,smart_Regulat_G_prot_signal_superfam,pfscan_Regulat_G_prot_signal_superfam,prints_RGS_dom	-	no_errors	RGS21	HGNC	ENSG00000253148	tier1			82	0	0.00	85	4	4.49	82	0	0.00	85	4	4.49
ESRP1	0	genome.wustl.edu	37	8	95677276	95677276	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	8	95677276	95677276	C	T	SNP	ESRP1	ENST00000433389	human	ensembl	74_37	+1	known	missense	c.877	p.R293W	1.000	smart_RRM_dom,pfscan_RRM_dom	superfamily_RNaseH-like_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	ESRP1	HGNC	ENSG00000104413	tier1	-	-	68	0	0.00	37	10	21.28	106	2	1.85	146	52	26.26
ATAD3C	0	genome.wustl.edu	37	1	1387815	1387815	+	Splice_Site	SNP	G	G	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	1387815	1387815	G	A	SNP	ATAD3C	ENST00000378785	human	ensembl	74_37	+1	known	splice_site	c.222+1	e3+1	1.000	-	-	-	no_errors	ATAD3C	HGNC	ENSG00000215915	tier1	-	-	112	0	0.00	25	36	59.02	105	2	1.87	90	9	9.09
DMD	0	genome.wustl.edu	37	X	33229530	33229530	+	R	SNP	C	C	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	X	33229530	33229530	C	G	SNP	DMD	ENST00000463609	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.902	-	-	-	no_errors	DMD	HGNC	ENSG00000198947	tier1	-	-	71	0	0.00	57	53	48.18	130	2	1.52	158	60	27.52
ACCS	0	genome.wustl.edu	37	11	44104733	44104733	+	Missense_Mutation	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	11	44104733	44104733	G	T	SNP	ACCS	ENST00000263776	human	ensembl	74_37	+1	known	missense	c.1126	p.V376L	0.999	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase	-	no_errors	ACCS	HGNC	ENSG00000110455	tier1	-	-	54	0	0.00	9	31	77.50	157	2	1.25	165	51	23.61
PLEKHO1	0	genome.wustl.edu	37	1	150128083	150128083	+	R	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	150128083	150128083	C	T	SNP	PLEKHO1	ENST00000477309	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	PLEKHO1	HGNC	ENSG00000023902	tier1	-	-	59	0	0.00	27	25	48.08	111	2	1.77	191	52	21.40
KHDRBS1	0	genome.wustl.edu	37	1	32503558	32503558	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	32503558	32503558	C	T	SNP	KHDRBS1	ENST00000327300	human	ensembl	74_37	+1	known	missense	c.1028	p.P343L	0.997	NULL	pfam_KH_dom_type_1,smart_KH_dom,pfscan_KH_dom_type_1	-	no_errors	KHDRBS1	HGNC	ENSG00000121774	tier1	-	-	52	0	0.00	75	29	27.88	34	1	2.86	89	11	11.00
MT1HL1	0	genome.wustl.edu	37	1	237167633	237167633	+	Missense_Mutation	SNP	C	C	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	1	237167633	237167633	C	T	SNP	MT1HL1	ENST00000464121	human	ensembl	74_37	-1	known	missense	c.40	p.A14T	0.006	pfam_Metalthion_sfam_euk,superfamily_Metalthion_dom,prints_Metalthion_vert	pfam_Metalthion_sfam_euk,superfamily_Metalthion_dom,prints_Metalthion_vert	-	no_errors	MT1HL1	HGNC	ENSG00000244020	tier1	-	-	47	0	0.00	12	17	58.62	5	0	0.00	7	1	12.50
RTL1	0	genome.wustl.edu	37	14	101347810	101347810	+	Missense_Mutation	SNP	A	A	G			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	14	101347810	101347810	A	G	SNP	RTL1	ENST00000534062	human	ensembl	74_37	-1	known	missense	c.3316	p.S1106P	0.000	NULL	pfam_Retrotrans_gag_dom,superfamily_Peptidase_aspartic_dom	-	no_errors	RTL1	HGNC	ENSG00000254656	tier1	-	-	26	0	0.00	16	8	33.33	9	0	0.00	6	0	0.00
LOC645752	0	genome.wustl.edu	37	15	78207077	78207077	+	R	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	15	78207077	78207077	G	T	SNP	LOC645752	ENST00000563349	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.019	-	-	-	no_errors	RP11-114H24.2	Clone_based_vega_gene	ENSG00000260776	tier1	-	-	121	1	0.82	140	57	28.93	0	0	0.00	0	0	0.00
NPIPA1	0	genome.wustl.edu	37	16	15045631	15045631	+	Missense_Mutation	SNP	G	G	A			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	16	15045631	15045631	G	A	SNP	NPIPA1	ENST00000328085	human	ensembl	74_37	+1	novel	missense	c.802	p.E268K	0.032	NULL	NULL	-	no_errors	NPIPA1	HGNC	ENSG00000183426	tier1	rs201805072	-	41	0	0.00	7	5	41.67	0	0	0.00	0	0	0.00
SPANXD	0	genome.wustl.edu	37	X	140786506	140786506	+	Missense_Mutation	SNP	G	G	T			TCGA-VT-A80J-01A-11D-A36J-09	TCGA-VT-A80J-11A-22D-A36M-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	695291d4-4e6c-46d1-aeff-2ddaf0fdd1ee	fd6129c3-faca-4233-9ba6-92cc70bcb0de	X	140786506	140786506	G	T	SNP	SPANXD	ENST00000370515	human	ensembl	74_37	-1	known	missense	c.57	p.N19K	0.016	pfam_SPANX_prot	pfam_SPANX_prot	-	no_errors	SPANXD	HGNC	ENSG00000196406	tier1	-	-	196	1	0.51	45	74	62.18	24	0	0.00	22	2	8.33