Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
HNRNPCL1	0	genome.wustl.edu	37	1	12907990	12907990	+	Silent	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	12907990	12907990	G	T	SNP	HNRNPCL1	ENST00000317869	human	ensembl	74_37	-1	known	silent	c.153	p.G51	1.000	pfam_RRM_dom,smart_RRM_dom,pirsf_hnRNP_C_Raly,pfscan_RRM_dom	pfam_RRM_dom,smart_RRM_dom,pirsf_hnRNP_C_Raly,pfscan_RRM_dom	-	no_errors	HNRNPCL1	HGNC	ENSG00000179172	tier1	-	-	283	0	0.00	290	45	13.43	166	0	0.00	150	22	12.79
LHCGR	0	genome.wustl.edu	37	2	48936105	48936105	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	2	48936105	48936105	G	A	SNP	LHCGR	ENST00000294954	human	ensembl	74_37	-1	known	missense	c.662	p.A221V	1.000	prints_TSH_rcpt	pfam_GPCR_Rhodpsn,prints_LSH_rcpt,prints_Gphrmn_rcpt_fam,prints_GPCR_Rhodpsn,prints_TSH_rcpt,pfscan_GPCR_Rhodpsn_7TM	-	no_errors	LHCGR	HGNC	ENSG00000138039	tier1	-	-	110	0	0.00	85	53	38.41	101	0	0.00	65	45	40.91
ZNF568	0	genome.wustl.edu	37	19	37440596	37440596	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	19	37440596	37440596	C	T	SNP	ZNF568	ENST00000333987	human	ensembl	74_37	+1	known	missense	c.541	p.L181F	0.000	NULL	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF568	HGNC	ENSG00000198453	tier1	-	-	47	0	0.00	87	10	10.31	105	0	0.00	174	26	13.00
DH7	0	genome.wustl.edu	37	2	196799353	196799353	+	Missense_Mutation	SNP	C	C	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	2	196799353	196799353	C	A	SNP	DH7	ENST00000312428	human	ensembl	74_37	-1	known	missense	c.3433	p.V1145F	1.000	pfam_Dynein_heavy_dom-2	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,superfamily_P-loop_NTPase,superfamily_Signal_recog_particle_SRP9/14,smart_AAA+_ATPase,pfscan_EF_hand_dom	-	no_errors	DH7	HGNC	ENSG00000118997	tier1	-	-	59	0	0.00	31	23	42.59	115	1	0.86	80	32	28.32
ALDH1A3	0	genome.wustl.edu	37	15	101438364	101438364	+	Missense_Mutation	SNP	C	C	G			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	15	101438364	101438364	C	G	SNP	ALDH1A3	ENST00000329841	human	ensembl	74_37	+1	known	missense	c.857	p.P286R	1.000	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	pfam_Aldehyde_DH_dom,superfamily_Ald_DH/histidinol_DH	-	no_errors	ALDH1A3	HGNC	ENSG00000184254	tier1	-	-	27	0	0.00	31	36	53.73	54	0	0.00	38	44	53.66
RSF1	0	genome.wustl.edu	37	11	77378084	77378084	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	11	77378084	77378084	C	T	SNP	RSF1	ENST00000308488	human	ensembl	74_37	-1	known	missense	c.4204	p.A1402T	1.000	NULL	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD,pfscan_Znf_PHD-finger	-	no_errors	RSF1	HGNC	ENSG00000048649	tier1	-	-	55	0	0.00	38	24	38.71	86	1	1.15	54	29	34.94
ACBD5	0	genome.wustl.edu	37	10	27499800	27499800	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	10	27499800	27499800	G	T	SNP	ACBD5	ENST00000375888	human	ensembl	74_37	-1	known	missense	c.1174	p.H392N	0.958	pirsf_M-assoc_diazepam-bd-inh	pfam_Acyl-CoA-binding_protein,superfamily_Acyl-CoA-binding_protein,pirsf_M-assoc_diazepam-bd-inh,prints_Acyl-CoA-binding_protein	-	no_errors	ACBD5	HGNC	ENSG00000107897	tier1	-	-	93	0	0.00	30	31	50.82	119	0	0.00	64	48	42.48
DGCR6	0	genome.wustl.edu	37	22	18898464	18898464	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	22	18898464	18898464	G	A	SNP	DGCR6	ENST00000331444	human	ensembl	74_37	+1	known	missense	c.436	p.D146N	1.000	pfam_DGCR6	pfam_DGCR6	-	no_errors	DGCR6	HGNC	ENSG00000183628	tier1	-	-	99	0	0.00	104	39	27.27	36	0	0.00	28	5	15.15
SLC4A4	0	genome.wustl.edu	37	4	72412066	72412066	+	Splice_Site	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	4	72412066	72412066	G	A	SNP	SLC4A4	ENST00000425175	human	ensembl	74_37	+1	known	splice_site	c.2443-1	e18-1	1.000	-	-	-	no_errors	SLC4A4	HGNC	ENSG00000080493	tier1	-	-	103	0	0.00	38	35	47.95	100	0	0.00	42	29	40.85
IGFBP5	0	genome.wustl.edu	37	2	217559222	217559222	+	Silent	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	2	217559222	217559222	G	A	SNP	IGFBP5	ENST00000233813	human	ensembl	74_37	-1	known	silent	c.277	p.L93	1.000	superfamily_Growth_fac_rcpt_N_dom,smart_IGFBP-like,prints_IGFBP_1-6_chordata	pfam_Thyroglobulin_1,pfam_IGFBP-like,superfamily_Thyroglobulin_1,superfamily_Growth_fac_rcpt_N_dom,smart_IGFBP-like,smart_Thyroglobulin_1,pfscan_Thyroglobulin_1,prints_IGFBP_1-6_chordata,prints_IGFBP-5	-	no_errors	IGFBP5	HGNC	ENSG00000115461	tier1	-	-	65	0	0.00	30	20	40.00	14	0	0.00	21	11	33.33
KCNH1	0	genome.wustl.edu	37	1	210977435	210977435	+	Nonsense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	210977435	210977435	G	T	SNP	KCNH1	ENST00000271751	human	ensembl	74_37	-1	known	nonsense	c.1536	p.Y512*	1.000	superfamily_cNMP-bd-like	pfam_Ion_trans_dom,pfam_cNMP-bd_dom,pfam_2pore_dom_K_chnl_dom,pfam_PAS_fold,superfamily_cNMP-bd-like,superfamily_PAS,smart_PAC,smart_cNMP-bd_dom,prints_K_chnl_volt-dep_EAG,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ERG,pfscan_cNMP-bd_dom,pfscan_PAS,pfscan_PAS-assoc_C,tigrfam_PAS	-	no_errors	KCNH1	HGNC	ENSG00000143473	tier1	-	-	102	0	0.00	49	29	37.18	117	0	0.00	76	64	45.71
TECTA	0	genome.wustl.edu	37	11	121037373	121037373	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	11	121037373	121037373	G	A	SNP	TECTA	ENST00000264037	human	ensembl	74_37	+1	known	missense	c.5470	p.G1824S	1.000	pfam_ZP_dom,smart_ZP_dom,pfscan_ZP_dom	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_ZP_dom,pfam_Nidogen_extracell_dom,pfam_TIL_dom,superfamily_TIL_dom,smart_Nidogen_extracell_dom,smart_VWC_out,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_EG-like_dom,smart_ZP_dom,pfscan_ZP_dom	-	no_errors	TECTA	HGNC	ENSG00000109927	tier1	-	-	72	0	0.00	41	18	30.51	93	0	0.00	42	37	46.84
FAM47C	0	genome.wustl.edu	37	X	37026659	37026659	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	X	37026659	37026659	G	A	SNP	FAM47C	ENST00000358047	human	ensembl	74_37	+1	known	missense	c.176	p.R59H	0.000	NULL	NULL	-	no_errors	FAM47C	HGNC	ENSG00000198173	tier1	-	-	106	0	0.00	54	33	37.93	40	0	0.00	19	13	40.62
RASSF9	0	genome.wustl.edu	37	12	86198968	86198968	+	Nonsense_Mutation	SNP	T	T	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	12	86198968	86198968	T	A	SNP	RASSF9	ENST00000361228	human	ensembl	74_37	-1	known	nonsense	c.820	p.K274*	0.017	NULL	smart_Ras-assoc,pfscan_Ras-assoc	-	no_errors	RASSF9	HGNC	ENSG00000198774	tier1	-	-	42	0	0.00	20	15	42.86	79	0	0.00	54	49	47.12
NF1	0	genome.wustl.edu	37	17	29553702	29553702	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	17	29553702	29553702	G	C	SNP	NF1	ENST00000358273	human	ensembl	74_37	+1	known	missense	c.2251	p.G751R	1.000	superfamily_ARM-type_fold	pfam_RasGAP,superfamily_Rho_GTPase_activation_prot,superfamily_ARM-type_fold,superfamily_CRAL-TRIO_dom,smart_RasGAP,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom,pfscan_RasGAP	-	no_errors	NF1	HGNC	ENSG00000196712	tier1	-	-	48	0	0.00	16	15	48.39	38	0	0.00	17	6	26.09
SYNGAP1	0	genome.wustl.edu	37	6	33411019	33411019	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	6	33411019	33411019	C	T	SNP	SYNGAP1	ENST00000418600	human	ensembl	74_37	+1	known	missense	c.2690	p.S897L	0.909	pfam_DUF3498	pfam_DUF3498,pfam_RasGAP,pfam_C2_dom,superfamily_Rho_GTPase_activation_prot,superfamily_C2_dom,smart_Pleckstrin_homology,smart_C2_dom,smart_RasGAP,pfscan_Pleckstrin_homology,pfscan_RasGAP	-	no_errors	SYNGAP1	HGNC	ENSG00000197283	tier1	-	-	72	0	0.00	24	21	46.67	12	0	0.00	12	8	40.00
CD3EAP	0	genome.wustl.edu	37	19	45912057	45912057	+	Silent	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	19	45912057	45912057	G	A	SNP	CD3EAP	ENST00000589804	human	ensembl	74_37	+1	known	silent	c.837	p.E279	0.006	NULL	pfam_D-dir_R_pol1_su_RPA34	-	no_errors	CD3EAP	HGNC	ENSG00000117877	tier1	-	-	44	0	0.00	26	15	36.59	73	0	0.00	36	19	34.55
OPN4	0	genome.wustl.edu	37	10	88418324	88418324	+	Silent	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	10	88418324	88418324	C	T	SNP	OPN4	ENST00000372071	human	ensembl	74_37	+1	known	silent	c.541	p.L181	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn,prints_Opsin	-	no_errors	OPN4	HGNC	ENSG00000122375	tier1	-	-	76	0	0.00	12	25	67.57	36	0	0.00	16	31	65.96
DICER1	0	genome.wustl.edu	37	14	95560464	95560464	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	14	95560464	95560464	C	T	SNP	DICER1	ENST00000343455	human	ensembl	74_37	-1	known	missense	c.5125	p.D1709N	1.000	pfam_RNase_III_dom,superfamily_RNase_III_dom,smart_RNase_III_dom,pfscan_RNase_III_dom	pfam_RNase_III_dom,pfam_PAZ_dom,pfam_Dicer_dimerisation_dom,pfam_Helicase_C,pfam_D/R_helicase_DEAD/DEAH_N,pfam_Helicase/UvrB_dom,superfamily_RNase_III_dom,superfamily_P-loop_NTPase,superfamily_PAZ_dom,smart_Helicase_ATP-bd,smart_Helicase_C,smart_PAZ_dom,smart_RNase_III_dom,smart_dsR-bd_dom,pfscan_PAZ_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C,pfscan_dsR-bd_dom,pfscan_RNase_III_dom	-	no_errors	DICER1	HGNC	ENSG00000100697	tier1	-	-	49	0	0.00	7	40	85.11	135	0	0.00	11	113	90.40
FAM47C	0	genome.wustl.edu	37	X	37026574	37026574	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	X	37026574	37026574	G	A	SNP	FAM47C	ENST00000358047	human	ensembl	74_37	+1	known	missense	c.91	p.A31T	0.002	NULL	NULL	-	no_errors	FAM47C	HGNC	ENSG00000198173	tier1	-	-	104	0	0.00	40	29	42.03	37	0	0.00	23	16	41.03
ZC4H2	0	genome.wustl.edu	37	X	64140081	64140081	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	X	64140081	64140081	G	T	SNP	ZC4H2	ENST00000374839	human	ensembl	74_37	-1	known	missense	c.278	p.S93Y	1.000	pfam_Znf-C4H2	pfam_Znf-C4H2	-	no_errors	ZC4H2	HGNC	ENSG00000126970	tier1	-	-	83	0	0.00	35	7	16.67	122	0	0.00	34	7	17.07
SGIP1	0	genome.wustl.edu	37	1	67160987	67160987	+	R	SNP	C	C	G			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	67160987	67160987	C	G	SNP	SGIP1	ENST00000320161	human	ensembl	74_37	+1	putative	rna	NULL	NULL	1.000	-	-	-	no_errors	SGIP1	HGNC	ENSG00000118473	tier1	-	-	60	0	0.00	18	14	43.75	30	0	0.00	15	15	50.00
APC	0	genome.wustl.edu	37	5	112128170	112128170	+	Missense_Mutation	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	5	112128170	112128170	G	A	SNP	APC	ENST00000257430	human	ensembl	74_37	+1	known	missense	c.673	p.E225K	1.000	NULL	pfam_APC_basic_dom,pfam_EB1-bd,pfam_APC_Cys-rich_rpt,pfam_Armadillo,pfam_APC_dom,pfam_SAMP,pfam_APC_15aa_rpt,superfamily_ARM-type_fold,smart_Armadillo,pfscan_Armadillo	-	no_errors	APC	HGNC	ENSG00000134982	tier1	-	-	83	0	0.00	36	36	49.32	110	0	0.00	68	24	26.09
FL	0	genome.wustl.edu	37	X	153583396	153583396	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	X	153583396	153583396	T	C	SNP	FL	ENST00000369850	human	ensembl	74_37	-1	known	missense	c.5014	p.I1672V	1.000	pfam_Filamin/ABP280_repeat-like,superfamily_Ig_E-set,smart_Filamin,pfscan_Filamin/ABP280_repeat-like	pfam_Filamin/ABP280_repeat-like,pfam_CH-domain,superfamily_CH-domain,superfamily_Ig_E-set,smart_CH-domain,smart_Filamin,pfscan_CH-domain,pfscan_Filamin/ABP280_repeat-like	-	no_errors	FL	HGNC	ENSG00000196924	tier1	-	-	45	0	0.00	22	19	46.34	92	0	0.00	64	59	47.97
QRICH2	0	genome.wustl.edu	37	17	74288739	74288739	+	Nonsense_Mutation	SNP	A	A	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	17	74288739	74288739	A	T	SNP	QRICH2	ENST00000262765	human	ensembl	74_37	-1	known	nonsense	c.1571	p.L524*	0.010	NULL	NULL	-	no_errors	QRICH2	HGNC	ENSG00000129646	tier1	-	-	89	0	0.00	51	44	46.32	29	0	0.00	32	20	38.46
DCAF11	0	genome.wustl.edu	37	14	24590047	24590047	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	14	24590047	24590047	G	T	SNP	DCAF11	ENST00000446197	human	ensembl	74_37	+1	known	missense	c.1093	p.G365C	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_WD_repeat_p23,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pirsf_WD_repeat_p23,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	DCAF11	HGNC	ENSG00000100897	tier1	-	-	33	0	0.00	24	26	52.00	97	0	0.00	57	82	58.99
ARHGAP30	0	genome.wustl.edu	37	1	161022582	161022582	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	161022582	161022582	C	T	SNP	ARHGAP30	ENST00000368013	human	ensembl	74_37	-1	known	missense	c.670	p.E224K	0.926	NULL	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP30	HGNC	ENSG00000186517	tier1	rs202221316	GMAF=0.0005	23	0	0.00	18	11	37.93	99	0	0.00	42	54	56.25
GSTCD	0	genome.wustl.edu	37	4	106629991	106629991	+	R	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	4	106629991	106629991	G	T	SNP	GSTCD	ENST00000515255	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	GSTCD	HGNC	ENSG00000138780	tier1	-	-	50	0	0.00	29	27	48.21	76	0	0.00	53	23	30.26
C9orf96	0	genome.wustl.edu	37	9	136270476	136270476	+	Missense_Mutation	SNP	C	C	G			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	9	136270476	136270476	C	G	SNP	C9orf96	ENST00000371957	human	ensembl	74_37	+1	known	missense	c.1974	p.F658L	0.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	C9orf96	HGNC	ENSG00000198870	tier1	-	-	13	0	0.00	6	5	45.45	19	0	0.00	14	22	61.11
AGPAT6	0	genome.wustl.edu	37	8	41467400	41467400	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	8	41467400	41467400	G	C	SNP	AGPAT6	ENST00000396987	human	ensembl	74_37	+1	known	missense	c.462	p.Q154H	0.983	NULL	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase	-	no_errors	AGPAT6	HGNC	ENSG00000158669	tier1	-	-	47	0	0.00	7	24	77.42	84	0	0.00	10	33	76.74
IFIH1	0	genome.wustl.edu	37	2	163136618	163136618	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	2	163136618	163136618	C	T	SNP	IFIH1	ENST00000263642	human	ensembl	74_37	-1	known	missense	c.1529	p.C510Y	1.000	superfamily_P-loop_NTPase,smart_Helicase_ATP-bd	pfam_RIG-I_C-RD,pfam_Helicase/UvrB_dom,pfam_D/R_helicase_DEAD/DEAH_N,pfam_Helicase_C,pfam_CARD,superfamily_P-loop_NTPase,superfamily_DEATH-like_dom,superfamily_ARM-type_fold,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	IFIH1	HGNC	ENSG00000115267	tier1	-	-	92	0	0.00	42	38	47.50	119	0	0.00	36	31	46.27
SETD5	0	genome.wustl.edu	37	3	9470539	9470539	+	R	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	3	9470539	9470539	C	T	SNP	SETD5	ENST00000468208	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	SETD5	HGNC	ENSG00000168137	tier1	-	-	32	0	0.00	15	11	42.31	72	0	0.00	46	39	45.35
TNFRSF21	0	genome.wustl.edu	37	6	47252150	47252150	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	6	47252150	47252150	G	T	SNP	TNFRSF21	ENST00000296861	human	ensembl	74_37	-1	known	missense	c.767	p.S256Y	0.999	NULL	pfam_Death_domain,superfamily_DEATH-like_dom,smart_TNFR/NGFR_Cys_rich_reg,smart_Death_domain,pfscan_Death_domain,pfscan_TNFR/NGFR_Cys_rich_reg,prints_TNFR_21	-	no_errors	TNFRSF21	HGNC	ENSG00000146072	tier1	-	-	67	0	0.00	31	19	38.00	63	0	0.00	42	33	44.00
ZDHHC13	0	genome.wustl.edu	37	11	19184856	19184856	+	Missense_Mutation	SNP	C	C	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	11	19184856	19184856	C	A	SNP	ZDHHC13	ENST00000446113	human	ensembl	74_37	+1	known	missense	c.1115	p.A372E	0.999	NULL	pfam_Ankyrin_rpt,pfam_Znf_DHHC_palmitoyltrfase,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_Znf_DHHC_palmitoyltrfase	-	no_errors	ZDHHC13	HGNC	ENSG00000177054	tier1	-	-	95	0	0.00	98	36	26.87	144	0	0.00	110	35	23.97
NONO	0	genome.wustl.edu	37	X	70520091	70520091	+	R	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	X	70520091	70520091	G	A	SNP	NONO	ENST00000473525	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	NONO	HGNC	ENSG00000147140	tier1	-	-	35	0	0.00	12	15	55.56	90	0	0.00	18	30	62.50
KCNH8	0	genome.wustl.edu	37	3	19432128	19432128	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	3	19432128	19432128	G	T	SNP	KCNH8	ENST00000328405	human	ensembl	74_37	+1	known	missense	c.967	p.V323L	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_cNMP-bd_dom,pfam_2pore_dom_K_chnl_dom,pfam_PAS_fold_3,pfam_PAS_4,pfam_PAS_fold,superfamily_cNMP-bd-like,superfamily_PAS,superfamily_tR-bd_arm,smart_PAC,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom,pfscan_PAS-assoc_C,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ELK,prints_K_chnl_volt-dep_ERG,prints_K_chnl_volt-dep_EAG,tigrfam_PAS	-	no_errors	KCNH8	HGNC	ENSG00000183960	tier1	-	-	87	0	0.00	47	22	31.88	93	0	0.00	62	26	29.55
PTPRU	0	genome.wustl.edu	37	1	29630418	29630418	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	29630418	29630418	C	T	SNP	PTPRU	ENST00000345512	human	ensembl	74_37	+1	known	missense	c.2558	p.S853F	0.999	NULL	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_MAM_dom,pfam_Fibronectin_type3,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_MAM_dom,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_MAM_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt,prints_MAM_dom	-	no_errors	PTPRU	HGNC	ENSG00000060656	tier1	-	-	65	0	0.00	33	31	48.44	12	0	0.00	13	7	35.00
SHPRH	0	genome.wustl.edu	37	6	146256227	146256227	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	6	146256227	146256227	G	C	SNP	SHPRH	ENST00000367503	human	ensembl	74_37	-1	known	missense	c.2806	p.R936G	1.000	pfam_SNF2_N,superfamily_P-loop_NTPase	pfam_SNF2_N,pfam_Histone_H1/H5_H15,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,superfamily_WW_dom,smart_Helicase_ATP-bd,smart_Histone_H1/H5_H15,smart_Znf_PHD,smart_Znf_RING,smart_Helicase_C,pfscan_Znf_RING,pfscan_Helicase_C	-	no_errors	SHPRH	HGNC	ENSG00000146414	tier1	-	-	69	0	0.00	43	10	18.52	109	0	0.00	63	14	18.18
AGBL2	0	genome.wustl.edu	37	11	47711627	47711627	+	Splice_Site	DEL	C	C	-			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	11	47711627	47711627	C	-	DEL	AGBL2	ENST00000357610	human	ensembl	74_37	-1	known	splice_site_del	c.1631+1	e9+1	1.000	-	-	-	no_errors	AGBL2	HGNC	ENSG00000165923	tier1			32	0	0.00	45	15	25.00	116	0	0.00	111	26	18.98
RSE8	0	genome.wustl.edu	37	14	21526082	21526084	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	CTG	CTG	CTG	-	CTG	CTG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	14	21526082	21526084	CTG	-	DEL	RSE8	ENST00000308227	human	ensembl	74_37	+1	known	in_frame_del	c.31_33	p.L14in_frame_del	0.001:0.002:0.001	NULL	pfam_RNaseA_domain,superfamily_RNaseA_domain,smart_RNaseA_domain,prints_RNaseA	-	no_errors	RSE8	HGNC	ENSG00000173431	tier1			49	0	0.00	19	4	17.39	46	0	0.00	27	3	10.00
MAPK15	0	genome.wustl.edu	37	8	144801595	144801595	+	Missense_Mutation	SNP	T	T	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	8	144801595	144801595	T	A	SNP	MAPK15	ENST00000338033	human	ensembl	74_37	+1	known	missense	c.664	p.S222T	0.997	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAPK15	HGNC	ENSG00000181085	tier1	rs139010308	-	166	0	0.00	14	103	87.29	21	0	0.00	5	25	83.33
SDK1	0	genome.wustl.edu	37	7	4169647	4169647	+	Nonsense_Mutation	SNP	C	C	G			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	7	4169647	4169647	C	G	SNP	SDK1	ENST00000404826	human	ensembl	74_37	+1	known	nonsense	c.4047	p.Y1349*	0.933	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Fibronectin_type3,pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	SDK1	HGNC	ENSG00000146555	tier1	-	-	78	0	0.00	40	33	45.21	10	0	0.00	7	13	65.00
TP53	0	genome.wustl.edu	37	17	7578443	7578443	+	Missense_Mutation	SNP	A	A	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	17	7578443	7578443	A	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.487	p.Y163N	1.000	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	32	0	0.00	5	22	81.48	52	0	0.00	9	28	75.68
ZBTB12	0	genome.wustl.edu	37	6	31868321	31868321	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	6	31868321	31868321	G	C	SNP	ZBTB12	ENST00000375527	human	ensembl	74_37	-1	known	missense	c.762	p.S254R	0.004	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	ZBTB12	HGNC	ENSG00000204366	tier1	-	-	80	0	0.00	67	46	40.71	24	0	0.00	8	10	55.56
MEG3	0	genome.wustl.edu	37	14	101299003	101299003	+	R	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	14	101299003	101299003	G	A	SNP	MEG3	ENST00000452120	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.046	-	-	-	no_errors	MEG3	HGNC	ENSG00000214548	tier1	-	-	42	0	0.00	45	17	26.56	78	0	0.00	69	6	8.00
KIT	0	genome.wustl.edu	37	4	55603360	55603360	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	4	55603360	55603360	T	C	SNP	KIT	ENST00000288135	human	ensembl	74_37	+1	known	missense	c.2716	p.C906R	1.000	pirsf_Tyr_kinase_CSF1/PDGF_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_CSF1/PDGF_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,pfam_Immunoglobulin,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom	-	no_errors	KIT	HGNC	ENSG00000157404	tier1	-	-	28	0	0.00	33	7	17.50	81	0	0.00	101	9	8.18
FAM182B	0	genome.wustl.edu	37	20	25840376	25840379	+	R	DEL	CCCA	CCCA	-			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	CCCA	CCCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	20	25840376	25840379	CCCA	-	DEL	FAM182B	ENST00000584356	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.030:0.028:0.026:0.024	-	-	-	no_errors	FAM182B	HGNC	ENSG00000175170	tier1			12	0	0.00	3	7	70.00	6	0	0.00	1	0	0.00
ROCK1P1	0	genome.wustl.edu	37	18	122175	122175	+	R	SNP	T	T	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	18	122175	122175	T	C	SNP	ROCK1P1	ENST00000608049	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	ROCK1P1	HGNC	ENSG00000263006	tier1	rs201110035	-	26	0	0.00	8	3	27.27	7	0	0.00	0	0	0.00
KRTAP10-9	0	genome.wustl.edu	37	21	46048196	46048197	+	R	INS	-	-	CGCTGGT			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	21	46048196	46048197	-	CGCTGGT	INS	KRTAP10-9	ENST00000484861	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001:0.001	-	-	-	no_errors	KRTAP10-9	HGNC	ENSG00000221837	tier1			4	0	0.00	1	0	0.00	4	0	0.00	1	0	0.00
KRTAP5-5	0	genome.wustl.edu	37	11	1651159	1651169	+	Frame_Shift_Del	DEL	GCTGTGGCTCT	GCTGTGGCTCT	-			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	GCTGTGGCTCT	GCTGTGGCTCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	11	1651159	1651169	GCTGTGGCTCT	-	DEL	KRTAP5-5	ENST00000399676	human	ensembl	74_37	+1	known	frame_shift_del	c.89_99	p.C31fs	0.384:0.317:0.302:0.301:0.281:0.273:0.283:0.273:0.229:0.033:0.002	NULL	NULL	-	no_errors	KRTAP5-5	HGNC	ENSG00000185940	tier1			1	0	0.00	1	0	0.00	1	0	0.00	1	0	0.00
LCNL1	0	genome.wustl.edu	37	9	139879882	139879882	+	R	SNP	G	G	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	9	139879882	139879882	G	C	SNP	LCNL1	ENST00000432827	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	LCNL1	HGNC	ENSG00000214402	tier1	-	-	53	0	0.00	37	4	9.76	3	0	0.00	2	0	0.00
LOC730102	0	genome.wustl.edu	37	1	178006883	178006883	+	R	SNP	A	A	C			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	178006883	178006883	A	C	SNP	LOC730102	ENST00000476232	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.905	-	-	-	no_errors	RP11-568K15.1	Clone_based_vega_gene	ENSG00000242193	tier1	-	-	60	0	0.00	48	12	20.00	4	0	0.00	3	0	0.00
LOC285556	0	genome.wustl.edu	37	4	100571171	100571171	+	Silent	SNP	G	G	A			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	4	100571171	100571171	G	A	SNP	LOC285556	ENST00000511828	human	ensembl	74_37	-1	putative	silent	c.4635	p.A1545	0.007	NULL	NULL	-	no_errors	RP11-766F14.2	Clone_based_vega_gene	ENSG00000248713	tier1	-	-	22	0	0.00	14	15	51.72	2	0	0.00	1	2	66.67
NBPF1	0	genome.wustl.edu	37	1	16907298	16907298	+	Silent	SNP	C	C	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	1	16907298	16907298	C	T	SNP	NBPF1	ENST00000430580	human	ensembl	74_37	-1	novel	silent	c.1533	p.L511	0.005	pfam_NBPF_dom	pfam_NBPF_dom	-	no_errors	NBPF1	HGNC	ENSG00000219481	tier1	-	-	1438	0	0.00	1492	131	8.07	165	0	0.00	180	2	1.10
SCAND2P	0	genome.wustl.edu	37	15	85178522	85178523	+	R	INS	-	-	T			TCGA-QQ-A8VH-01A-11D-A37C-09	TCGA-QQ-A8VH-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	e4b5a400-a49b-41a3-bff0-f3b8c36e36dd	a65e8e60-03c3-468b-acb5-075ff9096122	15	85178522	85178523	-	T	INS	SCAND2P	ENST00000427525	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.260:0.227	-	-	-	no_errors	SCAND2P	HGNC	ENSG00000176700	tier1			22	0	0.00	19	3	13.64	93	0	0.00	104	2	1.89