Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
LRRC48	0	genome.wustl.edu	37	17	17896105	17896105	+	Silent	SNP	C	C	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	17	17896105	17896105	C	T	SNP	LRRC48	ENST00000313838	human	ensembl	74_37	+1	known	silent	c.471	p.C157	0.739	NULL	NULL	-	no_errors	LRRC48	HGNC	ENSG00000171962	tier1	-	-	46	0	0.00	47	5	9.62	61	0	0.00	29	8	21.62
COL4A3	0	genome.wustl.edu	37	2	228104874	228104874	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	2	228104874	228104874	C	T	SNP	COL4A3	ENST00000396578	human	ensembl	74_37	+1	known	missense	c.160	p.P54S	0.853	pfam_Collagen	pfam_Collagen,pfam_Collagen_VI_NC,superfamily_C-type_lectin_fold,smart_Collagen_VI_NC	-	no_errors	COL4A3	HGNC	ENSG00000169031	tier1	-	-	35	0	0.00	43	4	8.51	85	0	0.00	61	11	15.28
AMBRA1	0	genome.wustl.edu	37	11	46568608	46568609	+	R	INS	-	-	A			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	-	-	-	A	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	11	46568608	46568609	-	A	INS	AMBRA1	ENST00000524783	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.032:0.881	-	-	-	no_errors	AMBRA1	HGNC	ENSG00000110497	tier1			22	0	0.00	26	4	13.33	27	0	0.00	13	2	13.33
GRIP1	0	genome.wustl.edu	37	12	67072671	67072671	+	Missense_Mutation	SNP	G	G	C			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	12	67072671	67072671	G	C	SNP	GRIP1	ENST00000359742	human	ensembl	74_37	-1	known	missense	c.14	p.S5C	1.000	NULL	pfam_PDZ,superfamily_PDZ,smart_PDZ,pfscan_PDZ	-	no_errors	GRIP1	HGNC	ENSG00000155974	tier1	-	-	41	0	0.00	51	5	8.93	88	0	0.00	59	5	7.58
SLC13A4	0	genome.wustl.edu	37	7	135377097	135377097	+	Silent	SNP	G	G	C			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	7	135377097	135377097	G	C	SNP	SLC13A4	ENST00000354042	human	ensembl	74_37	-1	known	silent	c.1194	p.V398	0.997	pfam_Na/sul_symport	pfam_Na/sul_symport,pfam_Cit_transptr-like_dom,pfam_DctM	-	no_errors	SLC13A4	HGNC	ENSG00000164707	tier1	-	-	82	0	0.00	122	19	13.48	109	0	0.00	96	7	6.80
PHF23	0	genome.wustl.edu	37	17	7140765	7140765	+	Missense_Mutation	SNP	T	T	C			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	17	7140765	7140765	T	C	SNP	PHF23	ENST00000320316	human	ensembl	74_37	-1	known	missense	c.98	p.D33G	1.000	NULL	pfam_Znf_PHD-finger,superfamily_Znf_FYVE_PHD,smart_Znf_PHD	-	no_errors	PHF23	HGNC	ENSG00000040633	tier1	-	-	78	0	0.00	85	8	8.60	103	0	0.00	88	6	6.38
AMZ1	0	genome.wustl.edu	37	7	2741852	2741906	+	R	DEL	TGTGTGCTACTCTGCCCCAGCCAGGCTGGCATTTTGCAGCCATGCAGCCTGGCTC	TGTGTGCTACTCTGCCCCAGCCAGGCTGGCATTTTGCAGCCATGCAGCCTGGCTC	-			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	TGTGTGCTACTCTGCCCCAGCCAGGCTGGCATTTTGCAGCCATGCAGCCTGGCTC	TGTGTGCTACTCTGCCCCAGCCAGGCTGGCATTTTGCAGCCATGCAGCCTGGCTC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	7	2741852	2741906	TGTGTGCTACTCTGCCCCAGCCAGGCTGGCATTTTGCAGCCATGCAGCCTGGCTC	-	DEL	AMZ1	ENST00000485540	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000:0.001:0.002:0.002:0.003:0.004:0.003:0.001:0.000:0.000:0.004:0.003:0.003:0.002:0.002:0.002:0.003:0.003:0.001:0.005:0.071:0.077:0.080:0.076:0.071:0.067:0.056:0.014:0.004:0.001:0.002:0.002:0.000:0.001:0.002:0.003:0.004:0.005:0.002:0.002:0.002:0.002:0.002:0.002:0.003:0.000:0.001:0.001:0.000:0.000:0.000:0.001:0.000:0.000	-	-	-	no_errors	AMZ1	HGNC	ENSG00000174945	tier1			2	0	0.00	2	0	0.00	2	0	0.00	2	0	0.00
GAPVD1	0	genome.wustl.edu	37	9	128025963	128025989	+	Splice_Site	DEL	CAGCACTCCATCTGTAGGTATGTCTGT	CAGCACTCCATCTGTAGGTATGTCTGT	-			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	CAGCACTCCATCTGTAGGTATGTCTGT	CAGCACTCCATCTGTAGGTATGTCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	9	128025963	128025989	CAGCACTCCATCTGTAGGTATGTCTGT	-	DEL	GAPVD1	ENST00000469528	human	ensembl	74_37	+1	known	splice_site_del	c.NULL	NULL	1.000:1.000:1.000:1.000:1.000:0.999:0.996:0.980:0.970:0.963:0.961:0.959:0.952:0.948:0.947:0.950:0.961:0.966:0.966:0.969:0.974:0.982:0.984:0.985:0.984:0.985:0.993	-	-	-	no_errors	GAPVD1	HGNC	ENSG00000165219	tier1			0	0	0.00	1	1	50.00	0	0	0.00	1	1	50.00
PLXNB3	0	genome.wustl.edu	37	X	153033837	153033837	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	X	153033837	153033837	G	T	SNP	PLXNB3	ENST00000538966	human	ensembl	74_37	+1	known	missense	c.1289	p.G430V	0.996	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Plexin_cytoplasmic_RasGAP_dom,pfam_IPT,pfam_Plexin_repeat,pfam_Semap_dom,superfamily_Semap_dom,superfamily_Rho_GTPase_activation_prot,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,pfscan_Semap_dom	-	no_errors	PLXNB3	HGNC	ENSG00000198753	tier1	-	-	17	0	0.00	14	4	22.22	4	0	0.00	8	0	0.00
POTEE	0	genome.wustl.edu	37	2	132022031	132022031	+	Silent	SNP	C	C	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	2	132022031	132022031	C	T	SNP	POTEE	ENST00000356920	human	ensembl	74_37	+1	known	silent	c.3003	p.G1001	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,smart_Actin-related,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Actin-related	-	no_errors	POTEE	HGNC	ENSG00000188219	tier1	-	-	19	0	0.00	11	5	29.41	0	0	0.00	0	1	100.00
RCVRN	0	genome.wustl.edu	37	17	9801316	9801317	+	R	INS	-	-	GTGTGTGCGC			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	17	9801316	9801317	-	GTGTGTGCGC	INS	RCVRN	ENST00000570909	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	RCVRN	HGNC	ENSG00000109047	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
APBA2	0	genome.wustl.edu	37	15	29393906	29393906	+	Missense_Mutation	SNP	G	G	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	15	29393906	29393906	G	T	SNP	APBA2	ENST00000558259	human	ensembl	74_37	+1	known	missense	c.1443	p.Q481H	0.998	pfam_PTB/PI_dom,smart_PTB/PI_dom,pfscan_PTB/PI_dom	pfam_PTB/PI_dom,pfam_PDZ,superfamily_PDZ,smart_PTB/PI_dom,smart_PDZ,pfscan_PDZ,pfscan_PTB/PI_dom	-	no_errors	APBA2	HGNC	ENSG00000034053	tier1	-	-	26	0	0.00	37	4	9.76	52	0	0.00	36	3	7.69
VRTN	0	genome.wustl.edu	37	14	74824312	74824312	+	Missense_Mutation	SNP	C	C	T			TCGA-QQ-A8VD-01A-42D-A38Z-09	TCGA-QQ-A8VD-10A-01D-A38Z-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	076d23f5-8017-4f0b-b9a1-462386d9e1ed	34a49c5e-6a61-43d0-82b6-2b597c3cbab8	14	74824312	74824312	C	T	SNP	VRTN	ENST00000256362	human	ensembl	74_37	+1	known	missense	c.826	p.R276C	0.846	pfam_Transposase_8	pfam_Transposase_8	-	no_errors	VRTN	HGNC	ENSG00000133980	tier1	-	-	43	0	0.00	59	6	9.23	29	0	0.00	31	3	8.57