Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PPP2R5D	0	genome.wustl.edu	37	6	42974819	42974819	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	6	42974819	42974819	G	T	SNP	PPP2R5D	ENST00000485511	human	ensembl	74_37	+1	known	nonsense	c.493	p.E165*	0.999	pfam_PP2A_B56,superfamily_ARM-type_fold,pirsf_PP2A_B56	pfam_PP2A_B56,superfamily_ARM-type_fold,pirsf_PP2A_B56	-	no_errors	PPP2R5D	HGNC	ENSG00000112640	tier1	-	-	42	0	0.00	14	3	17.65						
DHX35	0	genome.wustl.edu	37	20	37617497	37617497	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	20	37617497	37617497	C	T	SNP	DHX35	ENST00000252011	human	ensembl	74_37	+1	known	silent	c.387	p.G129	1.000	pfam_D/R_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_DUF1605,pfam_Helicase-assoc_dom,pfam_Helicase_C,pfam_D/R_helicase_DEAD/DEAH_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,smart_Helicase_C,smart_Helicase-assoc_dom,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	DHX35	HGNC	ENSG00000101452	tier1	-	-	28	0	0.00	15	3	16.67						
ANKFN1	0	genome.wustl.edu	37	17	54400786	54400786	+	R	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	17	54400786	54400786	C	T	SNP	ANKFN1	ENST00000572312	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.823	-	-	-	no_errors	ANKFN1	HGNC	ENSG00000153930	tier1	-	-	22	0	0.00	16	3	15.79						
C9orf78	0	genome.wustl.edu	37	9	132595850	132595850	+	R	DEL	T	T	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	9	132595850	132595850	T	-	DEL	C9orf78	ENST00000461762	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.032	-	-	-	no_errors	C9orf78	HGNC	ENSG00000136819	tier1			32	0	0.00	29	4	12.12						
SLK	0	genome.wustl.edu	37	10	105762924	105762924	+	Missense_Mutation	SNP	A	A	G			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	10	105762924	105762924	A	G	SNP	SLK	ENST00000369755	human	ensembl	74_37	+1	known	missense	c.1988	p.K663R	0.000	superfamily_Kinase-like_dom	pfam_PKK,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_UVR_dom,pfscan_Prot_kinase_dom	-	no_errors	SLK	HGNC	ENSG00000065613	tier1	-	-	45	0	0.00	27	3	10.00						
NBPF14	0	genome.wustl.edu	37	1	148024804	148024804	+	Missense_Mutation	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	148024804	148024804	C	A	SNP	NBPF14	ENST00000369219	human	ensembl	74_37	-1	known	missense	c.193	p.D65Y	0.011	NULL	pfam_NBPF_dom	-	no_errors	NBPF14	HGNC	ENSG00000122497	tier1	-	-	26	0	0.00	78	14	15.22						
CABS1	0	genome.wustl.edu	37	4	71201610	71201610	+	Missense_Mutation	SNP	T	T	C			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	4	71201610	71201610	T	C	SNP	CABS1	ENST00000273936	human	ensembl	74_37	+1	known	missense	c.854	p.L285P	0.000	NULL	NULL	-	no_errors	CABS1	HGNC	ENSG00000145309	tier1	-	-	49	0	0.00	14	18	56.25						
RRP7B	0	genome.wustl.edu	37	22	42970772	42970772	+	R	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	22	42970772	42970772	C	T	SNP	RRP7B	ENST00000357802	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RRP7B	HGNC	ENSG00000182841	tier1	-	-	61	0	0.00	21	4	16.00						
ENSG00000249149	0	genome.wustl.edu	37	5	72706210	72706210	+	R	DEL	A	A	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	5	72706210	72706210	A	-	DEL	ENSG00000249149	ENST00000505955	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	RP11-79P5.3	Clone_based_vega_gene	ENSG00000249149	tier1			13	0	0.00	11	2	15.38						
PLCB2	0	genome.wustl.edu	37	15	40594507	40594507	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	15	40594507	40594507	G	A	SNP	PLCB2	ENST00000260402	human	ensembl	74_37	-1	known	missense	c.416	p.T139M	0.155	pirsf_PLC-beta	pirsf_PLC-beta,pfam_PLipase_C_PInositol-sp_X_dom,pfam_PLC-beta_C,pfam_PLipase_C_Pinositol-sp_Y,pfam_PLipase_C_EF-hand-like,pfam_C2_dom,superfamily_PLC-like_Pdiesterase_TIM-brl,superfamily_C2_dom,smart_PLipase_C_PInositol-sp_X_dom,smart_PLipase_C_Pinositol-sp_Y,smart_C2_dom,prints_Pinositol_PLipase_C,pfscan_C2_dom,pfscan_PLipase_C_PInositol-sp_X_dom,pfscan_PLipase_C_Pinositol-sp_Y	-	no_errors	PLCB2	HGNC	ENSG00000137841	tier1	-	-	26	0	0.00	14	12	46.15						
DMRT2	0	genome.wustl.edu	37	9	1056545	1056545	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	9	1056545	1056545	G	T	SNP	DMRT2	ENST00000302441	human	ensembl	74_37	+1	known	nonsense	c.958	p.E320*	1.000	NULL	pfam_DM_D-bd,superfamily_DM_D-bd,smart_DM_D-bd,pfscan_DM_D-bd	-	no_errors	DMRT2	HGNC	ENSG00000173253	tier1	-	-	39	0	0.00	34	4	10.53						
GPR143	0	genome.wustl.edu	37	X	9711677	9711677	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	X	9711677	9711677	G	A	SNP	GPR143	ENST00000380929	human	ensembl	74_37	-1	known	missense	c.755	p.T252M	1.000	pfam_Ocular_alb1,pfam_GPCR_2_secretin-like	pfam_Ocular_alb1,pfam_GPCR_2_secretin-like,prints_Ocular_alb1	-	no_errors	GPR143	HGNC	ENSG00000101850	tier1	-	-	47	0	0.00	44	4	8.33						
NEXN	0	genome.wustl.edu	37	1	78408542	78408543	+	R	INS	-	-	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	78408542	78408543	-	T	INS	NEXN	ENST00000480732	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.007:0.000	-	-	-	no_errors	NEXN	HGNC	ENSG00000162614	tier1			44	0	0.00	13	3	18.75						
ZNF285	0	genome.wustl.edu	37	19	44892206	44892206	+	Silent	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	19	44892206	44892206	C	A	SNP	ZNF285	ENST00000330997	human	ensembl	74_37	-1	known	silent	c.201	p.S67	0.000	pfscan_Krueppel-associated_box	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF285	HGNC	ENSG00000267508	tier1	rs73557001	-	31	0	0.00	19	6	24.00						
RNF212	0	genome.wustl.edu	37	4	1087327	1087328	+	In_Frame_Ins	INS	-	-	CTGCCCAGGCTGGAGCCAGCC			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	4	1087327	1087328	-	CTGCCCAGGCTGGAGCCAGCC	INS	RNF212	ENST00000333673	human	ensembl	74_37	-1	known	in_frame_ins	c.722_721	p.S241in_frame_insWLAPAWAA	0.085:0.000	NULL	pfscan_Znf_RING	-	no_errors	RNF212	HGNC	ENSG00000178222	tier1														
ENO1	0	genome.wustl.edu	37	1	8925473	8925473	+	Missense_Mutation	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	8925473	8925473	C	T	SNP	ENO1	ENST00000234590	human	ensembl	74_37	-1	known	missense	c.736	p.V246I	1.000	pfam_Enolase_C,pirsf_Enolase,tigrfam_Enolase	pfam_Enolase_C,pfam_Enolase_N,pirsf_Enolase,prints_Enolase,tigrfam_Enolase	-	no_errors	ENO1	HGNC	ENSG00000074800	tier1	-	-	27	0	0.00	9	3	25.00						
POGK	0	genome.wustl.edu	37	1	166810314	166810314	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	166810314	166810314	G	T	SNP	POGK	ENST00000367875	human	ensembl	74_37	+1	known	nonsense	c.121	p.E41*	0.999	superfamily_Krueppel-associated_box	pfam_DDE_SF_endonuclease_CENPB-like,pfam_Brinker_D-bd,pfam_HTH_CenpB_D-bd_dom,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,superfamily_Homeodomain-like,smart_Krueppel-associated_box,smart_HTH_CenpB_D-bd_dom,pfscan_Krueppel-associated_box,pfscan_Krueppel-associated_box-rel	-	no_errors	POGK	HGNC	ENSG00000143157	tier1	-	-	31	0	0.00	58	7	10.77						
ENSG00000171658	0	genome.wustl.edu	37	3	185693044	185693044	+	R	DEL	T	T	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	3	185693044	185693044	T	-	DEL	ENSG00000171658	ENST00000423298	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.985	-	-	-	no_errors	RP11-443P15.2	Clone_based_vega_gene	ENSG00000171658	tier1			19	0	0.00	18	2	10.00						
SPTBN2	0	genome.wustl.edu	37	11	66468674	66468675	+	Frame_Shift_Ins	INS	-	-	TT			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	66468674	66468675	-	TT	INS	SPTBN2	ENST00000309996	human	ensembl	74_37	-1	known	frame_shift_ins	c.2896_2895	p.E965fs	1.000:0.970	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTBN2	HGNC	ENSG00000173898	tier1			23	0	0.00	9	7	43.75						
BICD1	0	genome.wustl.edu	37	12	32520618	32520618	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	32520618	32520618	G	T	SNP	BICD1	ENST00000281474	human	ensembl	74_37	+1	known	missense	c.2779	p.A927S	1.000	NULL	pfam_Bicaudal-D_microtubule-assoc,superfamily_SPOC_like_C_dom	-	no_errors	BICD1	HGNC	ENSG00000151746	tier1	-	-	28	0	0.00	34	4	10.53						
XPNPEP3	0	genome.wustl.edu	37	22	41278171	41278171	+	Frame_Shift_Del	DEL	A	A	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	22	41278171	41278171	A	-	DEL	XPNPEP3	ENST00000357137	human	ensembl	74_37	+1	known	frame_shift_del	c.579	p.M195fs	0.003	pfam_Aminopep_P_N	pfam_Pept_M24_structural-domain,pfam_Aminopep_P_N,superfamily_Pept_M24_structural-domain	-	no_errors	XPNPEP3	HGNC	ENSG00000196236	tier1			17	0	0.00	14	3	17.65						
GALNT6	0	genome.wustl.edu	37	12	51785401	51785402	+	R	INS	-	-	AGCCGC			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	51785401	51785402	-	AGCCGC	INS	GALNT6	ENST00000603203	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.021:0.127	-	-	-	no_errors	GALNT6	HGNC	ENSG00000139629	tier1														
NLRC3	0	genome.wustl.edu	37	16	3604283	3604283	+	Missense_Mutation	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	16	3604283	3604283	C	T	SNP	NLRC3	ENST00000448023	human	ensembl	74_37	-1	known	missense	c.2368	p.A790T	1.000	smart_Leu-rich_rpt_RNase_inh_sub-typ	superfamily_P-loop_NTPase,smart_Leu-rich_rpt_RNase_inh_sub-typ,pfscan_CHT_NTPase	-	no_errors	NLRC3	HGNC	ENSG00000167984	tier1	-	-	52	0	0.00	39	4	9.30						
NEB	0	genome.wustl.edu	37	2	152521285	152521285	+	Silent	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	2	152521285	152521285	G	A	SNP	NEB	ENST00000397345	human	ensembl	74_37	-1	known	silent	c.5331	p.I1777	0.564	pfam_Nebulin_35r-motif,smart_Nebulin_35r-motif,pfscan_Nebulin_35r-motif	pfam_Nebulin_35r-motif,pfam_SH3_domain,pfam_SH3_2,superfamily_SH3_domain,superfamily_Adhesion_dom,superfamily_6-PGluconate_DH_C-like,smart_Nebulin_35r-motif,smart_SH3_domain,pfscan_Nebulin_35r-motif,pfscan_SH3_domain,prints_Nebulin	-	no_errors	NEB	HGNC	ENSG00000183091	tier1	-	-	48	0	0.00	32	22	40.74						
MAP2K3	0	genome.wustl.edu	37	17	21206524	21206524	+	Missense_Mutation	SNP	C	C	G			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	17	21206524	21206524	C	G	SNP	MAP2K3	ENST00000342679	human	ensembl	74_37	+1	known	missense	c.546	p.S182R	1.000	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	MAP2K3	HGNC	ENSG00000034152	tier1	-	-	53	0	0.00	52	15	22.39						
ENSG00000257769	0	genome.wustl.edu	37	16	15702432	15702432	+	R	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	16	15702432	15702432	G	A	SNP	ENSG00000257769	ENST00000549756	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	CTB-193M12.1	Clone_based_vega_gene	ENSG00000257769	tier1	-	-	9	0	0.00	6	6	50.00						
FBLN2	0	genome.wustl.edu	37	3	13613042	13613042	+	Missense_Mutation	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	3	13613042	13613042	C	T	SNP	FBLN2	ENST00000404922	human	ensembl	74_37	+1	known	missense	c.1187	p.A396V	0.000	NULL	pfam_EGF-like_Ca-bd_dom,pfam_Anaphylatoxin/fibulin,superfamily_Anaphylatoxin_comp_syst,smart_EG-like_dom,smart_Anaphylatoxin/fibulin,smart_EGF-like_Ca-bd_dom,pfscan_Anaphylatoxin/fibulin,pfscan_EG-like_dom	-	no_errors	FBLN2	HGNC	ENSG00000163520	tier1	-	-	35	0	0.00	32	4	11.11						
JAKMIP3	0	genome.wustl.edu	37	10	133930998	133930998	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	10	133930998	133930998	G	T	SNP	JAKMIP3	ENST00000298622	human	ensembl	74_37	+1	known	nonsense	c.553	p.E185*	1.000	NULL	NULL	-	no_errors	JAKMIP3	HGNC	ENSG00000188385	tier1	-	-	29	0	0.00	12	3	20.00						
RAPGEF4	0	genome.wustl.edu	37	2	173782548	173782548	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	2	173782548	173782548	G	T	SNP	RAPGEF4	ENST00000397081	human	ensembl	74_37	+1	known	missense	c.463	p.A155S	1.000	superfamily_cNMP-bd-like,smart_cNMP-bd_dom	pfam_RasGRF_CDC25,pfam_cNMP-bd_dom,pfam_DEP_dom,pfam_Ras-like_Gua-exchang_fac_N,pfam_Ras-assoc,superfamily_Ras_GEF_dom,superfamily_cNMP-bd-like,smart_cNMP-bd_dom,smart_DEP_dom,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_cNMP-bd_dom,pfscan_DEP_dom,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N,prints_cAMP/cGMP_kin	-	no_errors	RAPGEF4	HGNC	ENSG00000091428	tier1	-	-	35	0	0.00	36	4	10.00						
TCEB3C	0	genome.wustl.edu	37	18	44554838	44554838	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	18	44554838	44554838	G	A	SNP	TCEB3C	ENST00000330682	human	ensembl	74_37	-1	known	missense	c.1376	p.P459L	0.023	NULL	pfam_R_pol_II_trans_fac_SIII_A,pfam_TFIIS_N,superfamily_TFIIS_N,smart_TFIIS/CRSP70_N_sub	-	no_errors	TCEB3C	HGNC	ENSG00000183791	tier1	-	-	26	0	0.00	31	5	13.89						
WLS	0	genome.wustl.edu	37	1	68564403	68564403	+	Missense_Mutation	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	68564403	68564403	C	A	SNP	WLS	ENST00000540432	human	ensembl	74_37	-1	known	missense	c.1550	p.C517F	0.001	NULL	NULL	-	no_errors	WLS	HGNC	ENSG00000116729	tier1	-	-	26	0	0.00	0	17	100.00						
BOD1L1	0	genome.wustl.edu	37	4	13616072	13616072	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	4	13616072	13616072	G	T	SNP	BOD1L1	ENST00000040738	human	ensembl	74_37	-1	known	missense	c.922	p.Q308K	0.023	NULL	NULL	-	no_errors	BOD1L1	HGNC	ENSG00000038219	tier1	-	-	43	0	0.00	45	4	8.00						
ENSG00000215527	0	genome.wustl.edu	37	18	12658668	12658668	+	R	SNP	T	T	C			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	18	12658668	12658668	T	C	SNP	ENSG00000215527	ENST00000585853	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	AP005482.1	Clone_based_vega_gene	ENSG00000215527	tier1	-	-	31	0	0.00	35	4	10.26						
CCDC24	0	genome.wustl.edu	37	1	44458252	44458252	+	Frame_Shift_Del	DEL	G	G	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	44458252	44458252	G	-	DEL	CCDC24	ENST00000372318	human	ensembl	74_37	+1	known	frame_shift_del	c.360	p.E121fs	0.998	NULL	NULL	-	no_errors	CCDC24	HGNC	ENSG00000159214	tier1			52	0	0.00	16	2	11.11						
KCNB2	0	genome.wustl.edu	37	8	73480540	73480540	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	8	73480540	73480540	G	T	SNP	KCNB2	ENST00000523207	human	ensembl	74_37	+1	known	missense	c.571	p.A191S	1.000	prints_K_chnl	pfam_K_chnl_volt-dep_Kv2,pfam_Ion_trans_dom,pfam_T1-type_BTB,pfam_2pore_dom_K_chnl_dom,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,prints_K_chnl,prints_K_chnl_volt-dep_Kv2.2,prints_K_chnl_volt-dep_Kv2,prints_K_chnl_volt-dep_Kv9,prints_K_chnl_volt-dep_Kv,prints_K_chnl_volt-dep_Kv6,prints_K_chnl_volt-dep_Kv3,prints_K_chnl_volt-dep_Kv8	-	no_errors	KCNB2	HGNC	ENSG00000182674	tier1	-	-	31	0	0.00	37	4	9.76						
KLHDC3	0	genome.wustl.edu	37	6	42986655	42986655	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	6	42986655	42986655	G	T	SNP	KLHDC3	ENST00000326974	human	ensembl	74_37	+1	known	missense	c.875	p.R292L	0.999	NULL	pfam_Kelch_2,pfam_Kelch_1	-	no_errors	KLHDC3	HGNC	ENSG00000124702	tier1	-	-	44	0	0.00	26	4	13.33						
ARID1B	0	genome.wustl.edu	37	6	157520041	157520041	+	Silent	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	6	157520041	157520041	G	A	SNP	ARID1B	ENST00000367148	human	ensembl	74_37	+1	known	silent	c.4230	p.P1410	1.000	NULL	pfam_DUF3518,pfam_ARID/BRIGHT_D-bd,superfamily_ARID/BRIGHT_D-bd,superfamily_ARM-type_fold,smart_ARID/BRIGHT_D-bd,pfscan_ARID/BRIGHT_D-bd	-	no_errors	ARID1B	HGNC	ENSG00000049618	tier1	-	-	81	0	0.00	57	40	41.24						
C5orf27	0	genome.wustl.edu	37	5	95194703	95194703	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	5	95194703	95194703	C	T	SNP	C5orf27	ENST00000357880	human	ensembl	74_37	+1	known	silent	c.270	p.S90	0.229	NULL	NULL	-	no_errors	C5orf27	HGNC	ENSG00000236882	tier1	-	-	22	0	0.00	24	4	14.29						
OS9	0	genome.wustl.edu	37	12	58109574	58109574	+	Missense_Mutation	SNP	G	G	C			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	58109574	58109574	G	C	SNP	OS9	ENST00000315970	human	ensembl	74_37	+1	known	missense	c.611	p.G204A	1.000	superfamily_Man6P_isomerase_rcpt-bd_dom	pfam_PRKCSH,superfamily_Man6P_isomerase_rcpt-bd_dom	-	no_errors	OS9	HGNC	ENSG00000135506	tier1	-	-	22	0	0.00	29	9	23.68						
MUC5B	0	genome.wustl.edu	37	11	1266537	1266537	+	Silent	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	1266537	1266537	G	T	SNP	MUC5B	ENST00000447027	human	ensembl	74_37	+1	known	silent	c.8436	p.L2812	0.000	NULL	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,pfam_VWF_C,superfamily_TIL_dom,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC5B	HGNC	ENSG00000117983	tier1	rs199659189	-	30	0	0.00	39	7	15.22						
PARP1	0	genome.wustl.edu	37	1	226549885	226549886	+	R	INS	-	-	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	226549885	226549886	-	T	INS	PARP1	ENST00000491816	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002:0.004	-	-	-	no_errors	PARP1	HGNC	ENSG00000143799	tier1			14	0	0.00	27	4	12.90						
CABP1	0	genome.wustl.edu	37	12	121094036	121094036	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	121094036	121094036	C	T	SNP	CABP1	ENST00000288616	human	ensembl	74_37	+1	known	silent	c.186	p.C62	1.000	NULL	pfam_EF_hand_dom,smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	CABP1	HGNC	ENSG00000157782	tier1	-	-	33	0	0.00	48	12	19.67						
ITGAM	0	genome.wustl.edu	37	16	31339499	31339499	+	Nonsense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	16	31339499	31339499	G	T	SNP	ITGAM	ENST00000544665	human	ensembl	74_37	+1	known	nonsense	c.2743	p.E915*	0.000	pfam_Integrin_alpha-2	pfam_Integrin_alpha-2,pfam_VWF_A,pfam_FG-GAP,pfam_Integrin_alpha_C_CS,smart_Int_alpha_beta-p,smart_VWF_A,pfscan_VWF_A,prints_Integrin_alpha	-	no_errors	ITGAM	HGNC	ENSG00000169896	tier1	-	-	49	0	0.00	42	4	8.70						
ENSG00000261759	0	genome.wustl.edu	37	16	19132369	19132369	+	R	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	16	19132369	19132369	G	T	SNP	ENSG00000261759	ENST00000567236	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.783	-	-	-	no_errors	RP11-626G11.3	Clone_based_vega_gene	ENSG00000261759	tier1	-	-	32	0	0.00	33	5	13.16						
A25	0	genome.wustl.edu	37	12	112491457	112491457	+	Missense_Mutation	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	112491457	112491457	G	T	SNP	A25	ENST00000261745	human	ensembl	74_37	-1	known	missense	c.1633	p.L545I	1.000	pfam_N-acetylTrfase_B_cplx_non-cat	pfam_N-acetylTrfase_B_cplx_non-cat,pfscan_TPR-contain_dom	-	no_errors	A25	HGNC	ENSG00000111300	tier1	-	-	13	0	0.00	15	9	37.50						
ACOX3	0	genome.wustl.edu	37	4	8396467	8396467	+	Silent	SNP	T	T	C			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	4	8396467	8396467	T	C	SNP	ACOX3	ENST00000356406	human	ensembl	74_37	-1	known	silent	c.1059	p.Q353	1.000	pfam_AcylCo_DH/oxidase_C,superfamily_AcylCo_DH/oxidase_C,pirsf_Acyl-CoA_oxidase	pfam_Acyl-CoA_oxidase_C,pfam_Acyl-CoA_Oxase/DH_cen-dom,pfam_AcylCo_DH/oxidase_C,superfamily_AcylCo_DH/oxidase_C,superfamily_AcylCoA_DH/oxidase_NM_dom,pirsf_Acyl-CoA_oxidase	-	no_errors	ACOX3	HGNC	ENSG00000087008	tier1	-	-	9	0	0.00	8	6	42.86						
SH2D2A	0	genome.wustl.edu	37	1	156777009	156777009	+	Silent	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	156777009	156777009	G	A	SNP	SH2D2A	ENST00000392306	human	ensembl	74_37	-1	known	silent	c.1161	p.D387	0.938	NULL	pfam_SH2,smart_SH2,pfscan_SH2	-	no_errors	SH2D2A	HGNC	ENSG00000027869	tier1	-	-	26	0	0.00	43	15	25.86						
CNTN5	0	genome.wustl.edu	37	11	100170065	100170065	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	100170065	100170065	G	A	SNP	CNTN5	ENST00000279463	human	ensembl	74_37	+1	known	missense	c.2557	p.V853I	1.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub,smart_Ig_sub2,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	CNTN5	HGNC	ENSG00000149972	tier1	rs202207695	-	39	0	0.00	22	17	43.59						
NLRP10	0	genome.wustl.edu	37	11	7981533	7981533	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	7981533	7981533	C	T	SNP	NLRP10	ENST00000328600	human	ensembl	74_37	-1	known	silent	c.1626	p.A542	0.271	NULL	pfam_DAPIN,superfamily_DEATH-like_dom,superfamily_P-loop_NTPase,pfscan_CHT_NTPase,pfscan_DAPIN	-	no_errors	NLRP10	HGNC	ENSG00000182261	tier1	-	-	27	0	0.00	20	16	44.44						
BCKDHA	0	genome.wustl.edu	37	19	41916828	41916828	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	19	41916828	41916828	C	T	SNP	BCKDHA	ENST00000595085	human	ensembl	74_37	+1	known	silent	c.391	p.L131	1.000	NULL	pfam_DH_E1,pfam_Transketolase_N	-	no_errors	BCKDHA	HGNC	ENSG00000248098	tier1	-	-	60	0	0.00	36	4	10.00						
ASZ1	0	genome.wustl.edu	37	7	117020090	117020090	+	Silent	SNP	G	G	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	7	117020090	117020090	G	T	SNP	ASZ1	ENST00000284629	human	ensembl	74_37	-1	known	silent	c.957	p.T319	0.003	pfam_SAM_2,pfam_SAM_type1,superfamily_SAM/pointed	pfam_Ankyrin_rpt,pfam_SAM_2,pfam_SAM_type1,superfamily_Ankyrin_rpt-contain_dom,superfamily_SAM/pointed,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,prints_Ankyrin_rpt	-	no_errors	ASZ1	HGNC	ENSG00000154438	tier1	-	-	32	0	0.00	21	3	12.50						
CDH13	0	genome.wustl.edu	37	16	83813649	83813649	+	Silent	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	16	83813649	83813649	C	T	SNP	CDH13	ENST00000566620	human	ensembl	74_37	+1	known	silent	c.1758	p.Y586	0.998	superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_pro_dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH13	HGNC	ENSG00000140945	tier1	-	-	33	0	0.00	31	4	11.43						
DH11	0	genome.wustl.edu	37	7	21757493	21757493	+	Silent	SNP	A	A	C			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	7	21757493	21757493	A	C	SNP	DH11	ENST00000328843	human	ensembl	74_37	+1	known	silent	c.7105	p.R2369	1.000	NULL	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH11	HGNC	ENSG00000105877	tier1	-	-	45	0	0.00	34	6	15.00						
TTN-AS1	0	genome.wustl.edu	37	2	179510603	179510603	+	R	SNP	A	A	G			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	2	179510603	179510603	A	G	SNP	TTN-AS1	ENST00000418062	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TTN-AS1	HGNC	ENSG00000237298	tier1	-	-	42	0	0.00	11	24	68.57						
MALAT1	0	genome.wustl.edu	37	11	65271779	65271780	+	R	INS	-	-	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	65271779	65271780	-	T	INS	MALAT1	ENST00000534336	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.994:0.994	-	-	-	no_errors	MALAT1	HGNC	ENSG00000251562	tier1			30	0	0.00	30	5	14.29						
GYS2	0	genome.wustl.edu	37	12	21716178	21716178	+	Nonsense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	12	21716178	21716178	G	A	SNP	GYS2	ENST00000261195	human	ensembl	74_37	-1	known	nonsense	c.925	p.R309*	1.000	pfam_Glycogen_synth	pfam_Glycogen_synth,pfam_Glyco_trans_1	-	no_errors	GYS2	HGNC	ENSG00000111713	tier1	-	-	33	0	0.00	28	14	33.33						
ABCC2	0	genome.wustl.edu	37	10	101590148	101590148	+	Missense_Mutation	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	10	101590148	101590148	C	A	SNP	ABCC2	ENST00000370449	human	ensembl	74_37	+1	known	missense	c.2705	p.T902N	1.000	tigrfam_Multidrug-R_assoc	pfam_ABC_transptr_TM_dom,pfam_ABC_transporter-like,superfamily_ABC1_TM_dom,superfamily_P-loop_NTPase,smart_AAA+_ATPase,pfscan_ABC_transporter-like,pfscan_ABC1_TM_dom,tigrfam_Multidrug-R_assoc	-	no_errors	ABCC2	HGNC	ENSG00000023839	tier1	-	-	58	0	0.00	37	4	9.76						
ENSG00000212939	0	genome.wustl.edu	37	22	49947411	49947411	+	R	SNP	A	A	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	A	A					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	22	49947411	49947411	A	T	SNP	ENSG00000212939	ENST00000391625	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP1-29C18.10	Clone_based_vega_gene	ENSG00000212939	tier1	-	-	31	0	0.00	1	13	92.86						
CBX8	0	genome.wustl.edu	37	17	77770335	77770335	+	Missense_Mutation	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	17	77770335	77770335	C	T	SNP	CBX8	ENST00000269385	human	ensembl	74_37	-1	known	missense	c.74	p.R25H	1.000	pfam_Chromo_domain,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,pfscan_Chromo_domain/shadow	pfam_Chromo_domain,superfamily_Chromodomain-like,smart_Chromo_domain/shadow,pfscan_Chromo_domain/shadow	-	no_errors	CBX8	HGNC	ENSG00000141570	tier1	-	-	29	0	0.00	28	5	15.15						
PLD1	0	genome.wustl.edu	37	3	171452702	171452702	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	3	171452702	171452702	G	A	SNP	PLD1	ENST00000351298	human	ensembl	74_37	-1	known	missense	c.493	p.R165C	0.024	pfam_Phox,superfamily_Phox,smart_Phox,pirsf_PLipase_D_euk,pfscan_Phox	pfam_Phox,pfam_PLipase_D/transphosphatidylase,pfam_Pleckstrin_homology,superfamily_Phox,smart_Phox,smart_Pleckstrin_homology,smart_PLipase_D/transphosphatidylase,pirsf_PLipase_D_euk,pfscan_Phox,pfscan_PLipase_D/transphosphatidylase	-	no_errors	PLD1	HGNC	ENSG00000075651	tier1	-	-	20	0	0.00	10	5	33.33						
BCL6B	0	genome.wustl.edu	37	17	6928000	6928000	+	Missense_Mutation	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	17	6928000	6928000	C	A	SNP	BCL6B	ENST00000293805	human	ensembl	74_37	+1	known	missense	c.682	p.P228T	0.457	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	BCL6B	HGNC	ENSG00000161940	tier1	-	-	46	0	0.00	39	4	9.30						
TPTE2P2	0	genome.wustl.edu	37	13	52793775	52793776	+	R	INS	-	-	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	13	52793775	52793776	-	A	INS	TPTE2P2	ENST00000606973	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002:0.003	-	-	-	no_errors	TPTE2P2	HGNC	ENSG00000272281	tier1			15	0	0.00	23	3	11.54						
CDK5RAP2	0	genome.wustl.edu	37	9	123215781	123215781	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	9	123215781	123215781	G	A	SNP	CDK5RAP2	ENST00000349780	human	ensembl	74_37	-1	known	missense	c.2746	p.P916S	0.003	NULL	pfam_Spindle_assoc	-	no_errors	CDK5RAP2	HGNC	ENSG00000136861	tier1	-	-	38	0	0.00	35	4	10.26						
PRDM13	0	genome.wustl.edu	37	6	100062378	100062378	+	Missense_Mutation	SNP	C	C	T			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	6	100062378	100062378	C	T	SNP	PRDM13	ENST00000369215	human	ensembl	74_37	+1	known	missense	c.1867	p.H623Y	1.000	smart_Znf_C2H2-like,pfscan_Znf_C2H2	smart_Znf_C2H2-like,pfscan_SET_dom,pfscan_Znf_C2H2	-	no_errors	PRDM13	HGNC	ENSG00000112238	tier1	-	-	19	0	0.00	14	4	22.22						
COL4A2-AS1	0	genome.wustl.edu	37	13	111160095	111160099	+	Splice_Site	DEL	GAGTC	GAGTC	-			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	GAGTC	GAGTC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	13	111160095	111160099	GAGTC	-	DEL	COL4A2-AS1	ENST00000417970	human	ensembl	74_37	-1	known	splice_site_del	c.NULL	NULL	0.000:0.001:0.009:0.008:0.007	-	-	-	no_errors	COL4A2-AS1	HGNC	ENSG00000232814	tier1														
RDX	0	genome.wustl.edu	37	11	110070369	110070369	+	Missense_Mutation	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	11	110070369	110070369	G	A	SNP	RDX	ENST00000530749	human	ensembl	74_37	-1	known	missense	c.1783	p.R595C	1.000	NULL	pirsf_ERM,pfam_ERM_C_dom,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,superfamily_Moesin_tail,superfamily_Adenylate_cyclase-assoc_CAP_N,smart_Band_41_domain,prints_Ez/rad/moesin_like,prints_Band_41_fam,pfscan_FERM_domain	-	no_errors	RDX	HGNC	ENSG00000137710	tier1	-	-	43	0	0.00	22	3	12.00						
TNS3	0	genome.wustl.edu	37	7	47343111	47343111	+	Missense_Mutation	SNP	C	C	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	7	47343111	47343111	C	A	SNP	TNS3	ENST00000311160	human	ensembl	74_37	-1	known	missense	c.2894	p.R965L	0.977	NULL	pfam_PTB,pfam_Tensin_phosphatase_C2-dom,pfam_SH2,superfamily_C2_dom,smart_Tyr_Pase_cat,smart_SH2,smart_PTB/PI_dom,pfscan_SH2,pfscan_Tyr/Dual-sp_Pase,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	TNS3	HGNC	ENSG00000136205	tier1	-	-	25	0	0.00	9	6	40.00						
ABR	0	genome.wustl.edu	37	17	961175	961175	+	R	SNP	C	C	G			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	17	961175	961175	C	G	SNP	ABR	ENST00000575770	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	ABR	HGNC	ENSG00000159842	tier1	-	-	26	0	0.00	23	7	23.33						
FHL3	0	genome.wustl.edu	37	1	38463098	38463098	+	Silent	SNP	G	G	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	1	38463098	38463098	G	A	SNP	FHL3	ENST00000373016	human	ensembl	74_37	-1	known	silent	c.822	p.G274	0.992	pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM	pfam_Znf_LIM,smart_Znf_LIM,pfscan_Znf_LIM	-	no_errors	FHL3	HGNC	ENSG00000183386	tier1	-	-	39	0	0.00	20	4	16.67						
ENSG00000257931	0	genome.wustl.edu	37	14	19969313	19969313	+	R	SNP	T	T	A			TCGA-PT-A8TR-01A-11D-A37C-09	TCGA-PT-A8TR-10A-01D-A37F-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq 2500	a50049df-aa30-4674-8d4b-59c52a4e6a72	cc16650a-701b-47d5-83f5-556b0619165a	14	19969313	19969313	T	A	SNP	ENSG00000257931	ENST00000547399	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.005	-	-	-	no_errors	CTD-2311B13.7	Clone_based_vega_gene	ENSG00000257931	tier1	rs201001641	-	13	0	0.00	8	4	33.33