Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
MED12L	0	genome.wustl.edu	37	3	151101578	151101578	+	Missense_Mutation	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	3	151101578	151101578	G	A	SNP	MED12L	ENST00000474524	human	ensembl	74_37	+1	known	missense	c.4587	p.M1529I	1.000	NULL	pfam_Mediator_Med12_LCEWAV,pfam_Mediator_Med12,pfam_Mediator_Med12_catenin-bd	-	no_errors	MED12L	HGNC	ENSG00000144893	tier1	-	-	59	0	0.00	32	20	38.46	89	0	0.00	44	29	39.73
OPTC	0	genome.wustl.edu	37	1	203468847	203468847	+	Silent	SNP	A	A	G			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	203468847	203468847	A	G	SNP	OPTC	ENST00000367222	human	ensembl	74_37	+1	known	silent	c.600	p.L200	0.997	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	OPTC	HGNC	ENSG00000188770	tier1	-	-	79	0	0.00	41	43	51.19	102	0	0.00	38	43	53.09
ARID1B	0	genome.wustl.edu	37	6	157521934	157521934	+	Silent	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	6	157521934	157521934	G	A	SNP	ARID1B	ENST00000367148	human	ensembl	74_37	+1	known	silent	c.4326	p.E1442	0.987	NULL	pfam_DUF3518,pfam_ARID/BRIGHT_D-bd,superfamily_ARID/BRIGHT_D-bd,superfamily_ARM-type_fold,smart_ARID/BRIGHT_D-bd,pfscan_ARID/BRIGHT_D-bd	-	no_errors	ARID1B	HGNC	ENSG00000049618	tier1	rs139512931	-	41	0	0.00	38	4	9.52	62	0	0.00	68	10	12.82
ENSG00000258727	0	genome.wustl.edu	37	14	24037134	24037134	+	R	SNP	G	G	C			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	14	24037134	24037134	G	C	SNP	ENSG00000258727	ENST00000555968	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	RP11-66N24.3	Clone_based_vega_gene	ENSG00000258727	tier1	-	-	39	0	0.00	20	12	37.50	58	0	0.00	32	22	40.00
TRIML1	0	genome.wustl.edu	37	4	189064937	189064937	+	R	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	4	189064937	189064937	C	T	SNP	TRIML1	ENST00000507581	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	TRIML1	HGNC	ENSG00000184108	tier1	-	-	43	0	0.00	21	16	43.24	73	0	0.00	27	29	51.79
ADAM6	0	genome.wustl.edu	37	14	106437040	106437040	+	R	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	14	106437040	106437040	G	A	SNP	ADAM6	ENST00000452053	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	ADAM6	HGNC	ENSG00000233988	tier1	-	-	95	0	0.00	41	42	50.60	53	0	0.00	35	16	31.37
RIMS1	0	genome.wustl.edu	37	6	72960727	72960727	+	Nonsense_Mutation	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	6	72960727	72960727	C	T	SNP	RIMS1	ENST00000521978	human	ensembl	74_37	+1	known	nonsense	c.2476	p.R826*	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_Znf_FYVE_PHD,superfamily_PDZ,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ,pfscan_Znf_FYVE-typ,pfscan_Znf_FYVE-rel	-	no_errors	RIMS1	HGNC	ENSG00000079841	tier1	-	-	35	0	0.00	16	15	48.39	115	0	0.00	57	44	43.56
TMEM244	0	genome.wustl.edu	37	6	130166922	130166922	+	Missense_Mutation	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	6	130166922	130166922	C	T	SNP	TMEM244	ENST00000368143	human	ensembl	74_37	-1	known	missense	c.109	p.V37M	0.000	pfam_Integral_membrane_SYS1-rel	pfam_Integral_membrane_SYS1-rel	-	no_errors	TMEM244	HGNC	ENSG00000203756	tier1	rs143949103	GMAF=0.0005	41	0	0.00	27	22	44.90	99	0	0.00	43	35	44.87
POLR3C	0	genome.wustl.edu	37	1	145598254	145598254	+	Missense_Mutation	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	145598254	145598254	C	T	SNP	POLR3C	ENST00000334163	human	ensembl	74_37	-1	known	missense	c.999	p.M333I	1.000	pfam_R_pol_III_Rpc82_C	pfam_R_pol_III_Rpc82_C,pfam_R_pol_III_RPC82-rel_HTH	-	no_errors	POLR3C	HGNC	ENSG00000186141	tier1	-	-	46	0	0.00	26	13	33.33	77	0	0.00	42	32	43.24
FAM184A	0	genome.wustl.edu	37	6	119345393	119345393	+	Nonsense_Mutation	SNP	C	C	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	6	119345393	119345393	C	A	SNP	FAM184A	ENST00000338891	human	ensembl	74_37	-1	known	nonsense	c.745	p.E249*	1.000	NULL	superfamily_Prefoldin	-	no_errors	FAM184A	HGNC	ENSG00000111879	tier1	-	-	79	0	0.00	61	11	15.28	134	0	0.00	109	23	17.42
GPR144	0	genome.wustl.edu	37	9	127232787	127232787	+	Missense_Mutation	SNP	C	C	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	9	127232787	127232787	C	A	SNP	GPR144	ENST00000334810	human	ensembl	74_37	+1	known	missense	c.2573	p.P858H	1.000	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like,prints_GPCR_2_secretin-like	pfam_GPCR_2_secretin-like,pfam_Pentaxin,pfam_GPS_dom,superfamily_ConA-like_lec_gl_sf,superfamily_C-type_lectin_fold,smart_Pentaxin,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2-like,prints_Pentaxin,prints_GPCR_2_secretin-like	-	no_errors	GPR144	HGNC	ENSG00000180264	tier1	-	-	130	0	0.00	77	27	25.96	2	0	0.00	10	3	23.08
TUBA8	0	genome.wustl.edu	37	22	18609580	18609580	+	Missense_Mutation	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	22	18609580	18609580	G	A	SNP	TUBA8	ENST00000330423	human	ensembl	74_37	+1	known	missense	c.835	p.E279K	1.000	pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tub_FtsZ_C,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Beta_tubulin	pfam_Tubulin_FtsZ_GTPase,pfam_Tubulin/FtsZ_2-layer-sand-dom,superfamily_Tubulin_FtsZ_GTPase,superfamily_Tub_FtsZ_C,smart_Tubulin_FtsZ_GTPase,smart_Tubulin/FtsZ_2-layer-sand-dom,prints_Alpha_tubulin,prints_Tubulin,prints_Epsilon_tubulin,prints_Delta_tubulin,prints_Beta_tubulin	-	no_errors	TUBA8	HGNC	ENSG00000183785	tier1	-	-	78	0	0.00	35	38	52.05	43	0	0.00	40	28	41.18
SLC22A14	0	genome.wustl.edu	37	3	38350537	38350537	+	Missense_Mutation	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	3	38350537	38350537	G	A	SNP	SLC22A14	ENST00000273173	human	ensembl	74_37	+1	known	missense	c.868	p.A290T	0.031	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_Sub_transporter,pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC22A14	HGNC	ENSG00000144671	tier1	-	-	129	0	0.00	103	56	35.22	77	0	0.00	42	21	33.33
TENM3	0	genome.wustl.edu	37	4	183267832	183267832	+	Silent	SNP	A	A	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	4	183267832	183267832	A	T	SNP	TENM3	ENST00000406950	human	ensembl	74_37	+1	known	silent	c.261	p.G87	0.995	pfam_Ten_N	pfam_Ten_N,pfam_EGF_extracell,superfamily_CarboxyPept-like_regulatory,superfamily_Cyt_c-like_dom,smart_EG-like_dom,pfscan_EG-like_dom,tigrfam_YD,tigrfam_Rhs_assc_core	-	no_errors	TENM3	HGNC	ENSG00000218336	tier1	-	-	79	0	0.00	84	8	8.70	143	0	0.00	101	20	16.39
GDF3	0	genome.wustl.edu	37	12	7843092	7843092	+	Silent	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	12	7843092	7843092	G	A	SNP	GDF3	ENST00000329913	human	ensembl	74_37	-1	known	silent	c.477	p.T159	0.000	pfam_TGF-b_N	pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C,prints_Inhibin_asu	-	no_errors	GDF3	HGNC	ENSG00000184344	tier1	-	-	43	0	0.00	23	33	58.93	80	0	0.00	54	42	43.75
EZR	0	genome.wustl.edu	37	6	159206479	159206479	+	Missense_Mutation	SNP	A	A	G			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	6	159206479	159206479	A	G	SNP	EZR	ENST00000337147	human	ensembl	74_37	-1	known	missense	c.329	p.I110T	0.998	pirsf_ERM,pfam_FERM_central,superfamily_FERM_central,smart_Band_41_domain,prints_Band_41_fam,pfscan_FERM_domain	pirsf_ERM,pfam_ERM_C_dom,pfam_FERM_PH-like_C,pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,superfamily_Moesin_tail,smart_Band_41_domain,prints_Ez/rad/moesin_like,prints_Band_41_fam,pfscan_FERM_domain	-	no_errors	EZR	HGNC	ENSG00000092820	tier1	-	-	98	0	0.00	55	36	39.56	56	0	0.00	32	24	42.86
LRRIQ3	0	genome.wustl.edu	37	1	74649253	74649253	+	Missense_Mutation	SNP	T	T	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	74649253	74649253	T	A	SNP	LRRIQ3	ENST00000354431	human	ensembl	74_37	-1	known	missense	c.116	p.H39L	1.000	NULL	pfscan_IQ_motif_EF-hand-BS	-	no_errors	LRRIQ3	HGNC	ENSG00000162620	tier1	-	-	44	0	0.00	13	12	48.00	81	0	0.00	49	38	43.68
SCN9A	0	genome.wustl.edu	37	2	167168143	167168143	+	Missense_Mutation	SNP	C	C	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	2	167168143	167168143	C	A	SNP	SCN9A	ENST00000303354	human	ensembl	74_37	-1	known	missense	c.124	p.D42Y	0.843	NULL	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,smart_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN9A	HGNC	ENSG00000169432	tier1	-	-	62	0	0.00	35	20	36.36	45	0	0.00	19	24	55.81
CRB1	0	genome.wustl.edu	37	1	197390617	197390617	+	Frame_Shift_Del	DEL	G	G	-			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	197390617	197390617	G	-	DEL	CRB1	ENST00000367400	human	ensembl	74_37	+1	known	frame_shift_del	c.1659	p.V554fs	0.002	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	pfam_EG-like_dom,pfam_Laminin_G,pfam_EGF_extracell,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G	-	no_errors	CRB1	HGNC	ENSG00000134376	tier1			60	0	0.00	33	40	54.79	116	0	0.00	55	38	40.86
LOC399715	0	genome.wustl.edu	37	10	6369914	6369914	+	R	DEL	G	G	-			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	10	6369914	6369914	G	-	DEL	LOC399715	ENST00000399868	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-563J2.2	Clone_based_vega_gene	ENSG00000215244	tier1			75	0	0.00	56	36	39.13	117	0	0.00	86	45	34.35
FAM204A	0	genome.wustl.edu	37	10	120081869	120081869	+	Missense_Mutation	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	10	120081869	120081869	C	T	SNP	FAM204A	ENST00000470476	human	ensembl	74_37	-1	known	missense	c.598	p.V200M	0.000	NULL	NULL	-	no_errors	FAM204A	HGNC	ENSG00000165669	tier1	-	-	22	0	0.00	2	13	86.67	87	0	0.00	3	47	94.00
PTEN	0	genome.wustl.edu	37	10	89692895	89692895	+	Missense_Mutation	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	10	89692895	89692895	G	A	SNP	PTEN	ENST00000371953	human	ensembl	74_37	+1	known	missense	c.379	p.G127R	1.000	pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Tyr/Dual-sp_Pase,pfscan_Phosphatase_tensin-typ	pfam_Tensin_phosphatase_C2-dom,pfam_Dual-sp_phosphatase_cat-dom,pfam_Tyr_Pase_rcpt/non-rcpt,superfamily_C2_dom,smart_Tyr_Pase_cat,pirsf_Bifunc_PIno_P3_Pase/Pase_PTEN,pfscan_Tyr/Dual-sp_Pase,pfscan_Phosphatase_tensin-typ,pfscan_Tensin_phosphatase_C2-dom	-	no_errors	PTEN	HGNC	ENSG00000171862	tier1	-	-	90	0	0.00	6	38	86.36	56	0	0.00	1	17	94.44
TTC6	0	genome.wustl.edu	37	14	38091983	38091983	+	Silent	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	14	38091983	38091983	G	A	SNP	TTC6	ENST00000533625	human	ensembl	74_37	+1	known	silent	c.714	p.E238	0.000	NULL	NULL	-	no_errors	TTC6	HGNC	ENSG00000139865	tier1	-	-	12	0	0.00	9	4	30.77	12	0	0.00	5	10	66.67
UBA6-AS1	0	genome.wustl.edu	37	4	68928384	68928384	+	R	SNP	T	T	C			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	4	68928384	68928384	T	C	SNP	UBA6-AS1	ENST00000500538	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	UBA6-AS1	HGNC	ENSG00000248049	tier1	-	-	78	0	0.00	56	29	34.12	21	0	0.00	9	4	30.77
SCN1A	0	genome.wustl.edu	37	2	166897761	166897761	+	Missense_Mutation	SNP	C	C	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	2	166897761	166897761	C	T	SNP	SCN1A	ENST00000303395	human	ensembl	74_37	-1	known	missense	c.2395	p.V799M	1.000	NULL	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,prints_Na_channel_a1su,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN1A	HGNC	ENSG00000144285	tier1	-	-	36	0	0.00	44	4	8.33	102	0	0.00	91	7	7.14
GDF2	0	genome.wustl.edu	37	10	48416492	48416492	+	Missense_Mutation	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	10	48416492	48416492	G	A	SNP	GDF2	ENST00000249598	human	ensembl	74_37	-1	known	missense	c.202	p.R68C	1.000	pfam_TGF-b_N	pfam_TGF-b_C,pfam_TGF-b_N,smart_TGF-b_C,prints_Inhibin_asu	-	no_errors	GDF2	HGNC	ENSG00000128802	tier1	-	-	48	0	0.00	64	6	8.57	136	0	0.00	102	5	4.59
AR	0	genome.wustl.edu	37	X	66765155	66765155	+	Missense_Mutation	SNP	T	T	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	X	66765155	66765155	T	A	SNP	AR	ENST00000374690	human	ensembl	74_37	+1	known	missense	c.167	p.L56Q	0.942	pfam_Andrgn_rcpt	pfam_Andrgn_rcpt,pfam_Znf_hrmn_rcpt,pfam_Nucl_hrmn_rcpt_lig-bd_core,superfamily_Nucl_hormone_rcpt_ligand-bd,smart_Znf_hrmn_rcpt,smart_Nucl_hrmn_rcpt_lig-bd_core,pfscan_Znf_hrmn_rcpt,prints_Andrgn_rcpt,prints_Znf_hrmn_rcpt	-	no_errors	AR	HGNC	ENSG00000169083	tier1	-	-	15	0	0.00	17	5	22.73	0	0	0.00	1	0	0.00
LOC440040	0	genome.wustl.edu	37	11	49830158	49830158	+	R	SNP	G	G	A			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	11	49830158	49830158	G	A	SNP	LOC440040	ENST00000527477	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.189	-	-	-	no_errors	RP11-707M1.1	Clone_based_vega_gene	ENSG00000205035	tier1	-	-	169	0	0.00	102	58	36.25	0	0	0.00	0	0	0.00
SH2B1	0	genome.wustl.edu	37	16	28875215	28875223	+	R	DEL	GCCGCCGCC	GCCGCCGCC	-			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	GCCGCCGCC	GCCGCCGCC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	16	28875215	28875223	GCCGCCGCC	-	DEL	SH2B1	ENST00000563674	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.968:0.615:0.267:1.000:1.000:1.000:0.999:0.964:0.945	-	-	-	no_errors	SH2B1	HGNC	ENSG00000178188	tier1			1	0	0.00	1	1	50.00	1	0	0.00	1	1	50.00
CDC42BPA	0	genome.wustl.edu	37	1	227257397	227257397	+	R	SNP	G	G	T			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	227257397	227257397	G	T	SNP	CDC42BPA	ENST00000488131	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	CDC42BPA	HGNC	ENSG00000143776	tier1	-	-	31	0	0.00	18	3	14.29	76	0	0.00	85	2	2.30
SMG5	0	genome.wustl.edu	37	1	156237384	156237423	+	Frame_Shift_Del	DEL	TGGGTGAGGAGGGCAGGTAGAAGAGGCAGAGGTTGAAGTC	TGGGTGAGGAGGGCAGGTAGAAGAGGCAGAGGTTGAAGTC	-			TCGA-IE-A4EK-01A-11D-A24N-09	TCGA-IE-A4EK-10A-01D-A24N-09	TGGGTGAGGAGGGCAGGTAGAAGAGGCAGAGGTTGAAGTC	TGGGTGAGGAGGGCAGGTAGAAGAGGCAGAGGTTGAAGTC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	56681386-d407-4f53-ae4f-6c04437652f7	0989420d-2639-41ee-912d-3526312eeb65	1	156237384	156237423	TGGGTGAGGAGGGCAGGTAGAAGAGGCAGAGGTTGAAGTC	-	DEL	SMG5	ENST00000361813	human	ensembl	74_37	-1	known	frame_shift_del	c.994_955	p.D319fs	0.982:1.000:1.000:0.998:0.963:0.996:0.995:0.914:0.996:0.996:0.994:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000:1.000	NULL	pfam_EST1,smart_PIN_dom	-	no_errors	SMG5	HGNC	ENSG00000198952	tier1			58	0	0.00	31	2	6.06	58	0	0.00	31	2	6.06