Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
ENSG00000233836	0	genome.wustl.edu	37	19	24014700	24014700	+	R	SNP	T	T	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	19	24014700	24014700	T	A	SNP	ENSG00000233836	ENST00000471224	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.812	-	-	-	no_errors	RP11-255H23.2	Clone_based_vega_gene	ENSG00000233836	tier1	-	-	24	0	0.00	7	9	56.25	30	0	0.00	14	5	26.32
HRNR	0	genome.wustl.edu	37	1	152191612	152191612	+	Silent	SNP	A	A	G			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	1	152191612	152191612	A	G	SNP	HRNR	ENST00000368801	human	ensembl	74_37	-1	known	silent	c.2493	p.H831	0.002	NULL	pfam_S100_Ca-bd_sub,pfscan_EF_hand_dom	-	no_errors	HRNR	HGNC	ENSG00000197915	tier1	-	-	85	0	0.00	57	26	31.33	64	0	0.00	48	29	37.66
RUSC2	0	genome.wustl.edu	37	9	35560483	35560483	+	Silent	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	9	35560483	35560483	C	T	SNP	RUSC2	ENST00000361226	human	ensembl	74_37	+1	known	silent	c.3846	p.I1282	0.938	NULL	pfam_Run,pfam_SH3_2,superfamily_SH3_domain,smart_Run,smart_SH3_domain,pfscan_Run,pfscan_SH3_domain	-	no_errors	RUSC2	HGNC	ENSG00000198853	tier1	-	-	44	0	0.00	29	22	43.14	42	0	0.00	38	27	41.54
NXF4	0	genome.wustl.edu	37	X	101821949	101821949	+	R	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	X	101821949	101821949	C	T	SNP	NXF4	ENST00000360035	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.061	-	-	-	no_errors	NXF4	HGNC	ENSG00000196970	tier1	-	-	80	0	0.00	49	41	45.56	76	0	0.00	38	42	52.50
KDM5C	0	genome.wustl.edu	37	X	53239969	53239969	+	Missense_Mutation	SNP	T	T	C			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	X	53239969	53239969	T	C	SNP	KDM5C	ENST00000375401	human	ensembl	74_37	-1	known	missense	c.1472	p.N491S	1.000	smart_JmjC_dom,pfscan_JmjC_dom	pfam_Lys_sp_deMease_like_dom,pfam_JmjC_dom,pfam_ARID/BRIGHT_D-bd,pfam_Znf_C5HC2,pfam_Znf_PHD-finger,pfam_TF_JmjN,superfamily_ARID/BRIGHT_D-bd,superfamily_Znf_FYVE_PHD,smart_TF_JmjN,smart_ARID/BRIGHT_D-bd,smart_Znf_PHD,smart_JmjC_dom,pfscan_TF_JmjN,pfscan_JmjC_dom,pfscan_Znf_PHD-finger,pfscan_ARID/BRIGHT_D-bd	-	no_errors	KDM5C	HGNC	ENSG00000126012	tier1	-	-	45	0	0.00	18	15	45.45	72	0	0.00	53	31	36.90
KLHL11	0	genome.wustl.edu	37	17	40011164	40011164	+	Missense_Mutation	SNP	C	C	G			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	17	40011164	40011164	C	G	SNP	KLHL11	ENST00000319121	human	ensembl	74_37	-1	known	missense	c.955	p.V319L	0.997	NULL	pfam_BACK,pfam_BTB_POZ,pfam_Kelch_1,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pfscan_BTB/POZ-like	-	no_errors	KLHL11	HGNC	ENSG00000178502	tier1	-	-	29	0	0.00	13	6	31.58	70	0	0.00	50	44	46.32
ABCC3	0	genome.wustl.edu	37	17	48757261	48757261	+	Splice_Site	SNP	G	G	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	17	48757261	48757261	G	A	SNP	ABCC3	ENST00000285238	human	ensembl	74_37	+1	known	splice_site	c.3807+1	e26+1	1.000	-	-	-	no_errors	ABCC3	HGNC	ENSG00000108846	tier1	-	-	31	0	0.00	20	16	44.44	96	0	0.00	77	48	38.40
FRMD1	0	genome.wustl.edu	37	6	168461515	168461515	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	6	168461515	168461515	C	T	SNP	FRMD1	ENST00000283309	human	ensembl	74_37	-1	known	missense	c.1268	p.G423E	0.000	NULL	pfam_FERM_central,pfam_FERM_N,superfamily_FERM_central,smart_Band_41_domain,pfscan_FERM_domain	-	no_errors	FRMD1	HGNC	ENSG00000153303	tier1	-	-	83	0	0.00	63	44	41.12	36	0	0.00	19	18	48.65
ENSG00000212768	0	genome.wustl.edu	37	15	35271833	35271833	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	15	35271833	35271833	C	A	SNP	ENSG00000212768	ENST00000391457	human	ensembl	74_37	+1	known	missense	c.60	p.S20R	0.003	NULL	NULL	-	no_errors	AC114546.1	Clone_based_ensembl_gene	ENSG00000212768	tier1	-	-	45	0	0.00	24	18	42.86	32	0	0.00	23	18	43.90
ZBBX	0	genome.wustl.edu	37	3	167031769	167031769	+	Silent	SNP	A	A	G			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	3	167031769	167031769	A	G	SNP	ZBBX	ENST00000307529	human	ensembl	74_37	-1	known	silent	c.1410	p.N470	0.001	NULL	pfam_Znf_B-box	-	no_errors	ZBBX	HGNC	ENSG00000169064	tier1	-	-	25	0	0.00	17	16	48.48	92	0	0.00	53	49	48.04
TP53	0	genome.wustl.edu	37	17	7579415	7579415	+	Nonsense_Mutation	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	17	7579415	7579415	C	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	nonsense	c.272	p.W91*	1.000	NULL	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	54	0	0.00	5	17	77.27	70	0	0.00	17	29	63.04
ANKRD44	0	genome.wustl.edu	37	2	197857417	197857417	+	R	SNP	A	A	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	2	197857417	197857417	A	T	SNP	ANKRD44	ENST00000486006	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.984	-	-	-	no_errors	ANKRD44	HGNC	ENSG00000065413	tier1	-	-	54	0	0.00	28	21	42.86	108	0	0.00	88	56	38.89
ARHGAP27	0	genome.wustl.edu	37	17	43474297	43474297	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	17	43474297	43474297	C	T	SNP	ARHGAP27	ENST00000428638	human	ensembl	74_37	-1	known	missense	c.1936	p.A646T	0.000	NULL	pfam_RhoGAP_dom,pfam_WW_dom,pfam_Pleckstrin_homology,superfamily_Rho_GTPase_activation_prot,superfamily_SH3_domain,superfamily_WW_dom,smart_WW_dom,smart_Pleckstrin_homology,smart_RhoGAP_dom,pfscan_Pleckstrin_homology,pfscan_SH3_domain,pfscan_WW_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP27	HGNC	ENSG00000159314	tier1	-	-	60	0	0.00	36	16	30.19	34	0	0.00	22	12	35.29
FKBP10	0	genome.wustl.edu	37	17	39976138	39976138	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	17	39976138	39976138	G	T	SNP	FKBP10	ENST00000544340	human	ensembl	74_37	+1	known	missense	c.245	p.R82L	0.000	pfam_PPIase_FKBP_dom,pfscan_PPIase_FKBP_dom	pfam_PPIase_FKBP_dom,smart_EF_hand_dom,pfscan_EF_hand_dom,pfscan_PPIase_FKBP_dom	-	no_errors	FKBP10	HGNC	ENSG00000141756	tier1	-	-	34	0	0.00	10	14	58.33	67	0	0.00	67	36	34.95
ARL13A	0	genome.wustl.edu	37	X	100229170	100229170	+	Silent	SNP	G	G	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	X	100229170	100229170	G	T	SNP	ARL13A	ENST00000450457	human	ensembl	74_37	+1	known	silent	c.114	p.V38	0.000	pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_MIRO-like,pfam_Small_GTPase,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_SAR1,prints_Small_GTPase_ARF/SAR	pfam_Small_GTPase_ARF/SAR,pfam_SRP_receptor_beta_su,pfam_MIRO-like,pfam_Small_GTPase,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_SAR1,prints_Small_GTPase_ARF/SAR	-	no_errors	ARL13A	HGNC	ENSG00000174225	tier1	-	-	61	0	0.00	32	30	48.39	105	0	0.00	53	37	41.11
DMD	0	genome.wustl.edu	37	X	32481570	32481570	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	X	32481570	32481570	G	T	SNP	DMD	ENST00000357033	human	ensembl	74_37	-1	known	missense	c.3418	p.H1140N	0.016	pfam_Spectrin_repeat,smart_Spectrin/alpha-actinin,pirsf_Dystrophin/utrophin	pfam_Spectrin_repeat,pfam_EF-hand_dom_typ1,pfam_EF-hand_dom_typ2,pfam_CH-domain,pfam_Znf_ZZ,pfam_WW_dom,pfam_CAMSAP_CH,superfamily_CH-domain,superfamily_WW_dom,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_WW_dom,smart_Znf_ZZ,pirsf_Dystrophin/utrophin,pfscan_CH-domain,pfscan_WW_dom,pfscan_Znf_ZZ	-	no_errors	DMD	HGNC	ENSG00000198947	tier1	-	-	83	0	0.00	33	34	50.75	105	1	0.94	69	45	39.13
INPP4A	0	genome.wustl.edu	37	2	99169399	99169399	+	Silent	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	2	99169399	99169399	C	T	SNP	INPP4A	ENST00000074304	human	ensembl	74_37	+1	known	silent	c.1329	p.G443	0.990	NULL	superfamily_C2_dom	-	no_errors	INPP4A	HGNC	ENSG00000040933	tier1	-	-	27	0	0.00	33	13	28.26	40	0	0.00	33	23	41.07
TYK2	0	genome.wustl.edu	37	19	10463145	10463145	+	Silent	SNP	G	G	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	19	10463145	10463145	G	A	SNP	TYK2	ENST00000264818	human	ensembl	74_37	-1	known	silent	c.3283	p.L1095	1.000	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Tyr_kinase_non-rcpt_Jak/Tyk2,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,superfamily_FERM_central,smart_Band_41_domain,smart_SH2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Tyr_kinase_non-rcpt_Jak/Tyk2,pfscan_FERM_domain,pfscan_Prot_kinase_dom,prints_Tyr_kinase_non-rcpt_Jak/Tyk2,prints_Ser-Thr/Tyr_kinase_cat_dom,prints_Tyr_kinase_non-rcpt_TYK2_N	-	no_errors	TYK2	HGNC	ENSG00000105397	tier1	-	-	63	0	0.00	41	29	41.43	39	0	0.00	33	30	47.62
MTNR1A	0	genome.wustl.edu	37	4	187454917	187454917	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	4	187454917	187454917	C	T	SNP	MTNR1A	ENST00000307161	human	ensembl	74_37	-1	known	missense	c.979	p.V327M	0.049	prints_Mel_1A_rcpt,prints_Mel_rcpt_1C	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_serpentine_rcpt_Srx,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Melatonin_rcpt,prints_GPCR_Rhodpsn,prints_Mel_1A_rcpt,prints_NPY_rcpt,prints_Mel_rcpt_1C	-	no_errors	MTNR1A	HGNC	ENSG00000168412	tier1	-	-	83	0	0.00	48	36	42.86	109	0	0.00	59	70	53.85
LPPR5	0	genome.wustl.edu	37	1	99422183	99422183	+	Nonsense_Mutation	SNP	G	G	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	1	99422183	99422183	G	A	SNP	LPPR5	ENST00000263177	human	ensembl	74_37	-1	known	nonsense	c.352	p.R118*	0.780	superfamily_P_Acid_Pase_2/haloperoxidase	pfam_P_Acid_Pase_2/haloperoxidase,superfamily_P_Acid_Pase_2/haloperoxidase,smart_P_Acid_Pase_2/haloperoxidase	-	no_errors	LPPR5	Uniprot_gn	ENSG00000117598	tier1	-	-	51	0	0.00	21	10	32.26	101	0	0.00	70	45	39.13
PTPRM	0	genome.wustl.edu	37	18	8244162	8244162	+	Missense_Mutation	SNP	G	G	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	18	8244162	8244162	G	A	SNP	PTPRM	ENST00000400060	human	ensembl	74_37	+1	known	missense	c.2407	p.D803N	1.000	NULL	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_MAM_dom,pfam_Fibronectin_type3,pfam_Immunoglobulin,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,smart_MAM_dom,smart_Ig_sub,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_MAM_dom,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,pfscan_Ig-like_dom,prints_Tyr_Pase_rcpt/non-rcpt,prints_MAM_dom	-	no_errors	PTPRM	HGNC	ENSG00000173482	tier1	-	-	47	0	0.00	24	24	50.00	80	0	0.00	33	39	54.17
MCF2	0	genome.wustl.edu	37	X	138678809	138678809	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	X	138678809	138678809	G	T	SNP	MCF2	ENST00000370578	human	ensembl	74_37	-1	known	missense	c.2611	p.L871I	0.977	smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_DH-domain,superfamily_DH-domain,superfamily_CRAL-TRIO_dom,smart_CRAL-TRIO_dom,smart_Spectrin/alpha-actinin,smart_DH-domain,smart_Pleckstrin_homology,pfscan_CRAL-TRIO_dom,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	MCF2	HGNC	ENSG00000101977	tier1	-	-	80	0	0.00	28	28	50.00	68	0	0.00	67	31	31.63
MUC4	0	genome.wustl.edu	37	3	195516077	195516077	+	Missense_Mutation	SNP	A	A	G			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	3	195516077	195516077	A	G	SNP	MUC4	ENST00000463781	human	ensembl	74_37	-1	known	missense	c.2374	p.S792P	0.002	NULL	pfam_Nidogen_extracell_dom,pfam_AMOP,pfam_VWF_type-D,smart_Nidogen_extracell_dom,smart_AMOP,smart_VWF_type-D,smart_EG-like_dom,pfscan_AMOP,pfscan_EG-like_dom	-	no_errors	MUC4	HGNC	ENSG00000145113	tier1	-	-	21	0	0.00	9	15	60.00	71	0	0.00	58	30	34.09
TFDP1	0	genome.wustl.edu	37	13	114277516	114277516	+	Missense_Mutation	SNP	T	T	G			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	13	114277516	114277516	T	G	SNP	TFDP1	ENST00000375370	human	ensembl	74_37	+1	known	missense	c.101	p.V34G	1.000	pirsf_Transcrpt_fac_DP	pfam_Transc_factor_DP_C,pfam_E2F_TDP,pirsf_Transcrpt_fac_DP	-	no_errors	TFDP1	HGNC	ENSG00000198176	tier1	-	-	46	0	0.00	11	25	69.44	50	0	0.00	15	34	69.39
C20orf62	0	genome.wustl.edu	37	20	43080770	43080770	+	Missense_Mutation	SNP	C	C	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	20	43080770	43080770	C	A	SNP	C20orf62	ENST00000306731	human	ensembl	74_37	-1	putative	missense	c.218	p.S73I	0.000	NULL	NULL	-	no_errors	C20orf62	HGNC	ENSG00000168746	tier1	-	-	46	0	0.00	56	7	11.11	103	0	0.00	108	19	14.96
OR5M8	0	genome.wustl.edu	37	11	56258788	56258788	+	Missense_Mutation	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	11	56258788	56258788	C	T	SNP	OR5M8	ENST00000327216	human	ensembl	74_37	-1	known	missense	c.59	p.R20Q	0.000	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR5M8	HGNC	ENSG00000181371	tier1	-	-	18	0	0.00	7	9	56.25	39	0	0.00	23	12	34.29
SAG	0	genome.wustl.edu	37	2	234255546	234255546	+	Silent	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	2	234255546	234255546	C	T	SNP	SAG	ENST00000409110	human	ensembl	74_37	+1	known	silent	c.1206	p.D402	0.000	NULL	pfam_Arrestin-like_N,pfam_Arrestin_C-like,superfamily_Ig_E-set,prints_Arrestin	-	no_errors	SAG	HGNC	ENSG00000130561	tier1	-	-	63	0	0.00	35	29	45.31	71	0	0.00	44	49	52.69
SLC27A2	0	genome.wustl.edu	37	15	50515326	50515326	+	Silent	SNP	T	T	C			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	15	50515326	50515326	T	C	SNP	SLC27A2	ENST00000267842	human	ensembl	74_37	+1	known	silent	c.1137	p.G379	0.775	pfam_AMP-dep_Synth/Lig	pfam_AMP-dep_Synth/Lig	-	no_errors	SLC27A2	HGNC	ENSG00000140284	tier1	-	-	43	0	0.00	33	22	40.00	85	0	0.00	62	44	41.51
ZHX1	0	genome.wustl.edu	37	8	124266184	124266185	+	Frame_Shift_Ins	INS	-	-	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	8	124266184	124266185	-	T	INS	ZHX1	ENST00000297857	human	ensembl	74_37	-1	known	frame_shift_ins	c.2003_2002	p.T668fs	1.000:0.969	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Znf_C2H2	-	no_errors	ZHX1	HGNC	ENSG00000165156	tier1			63	0	0.00	33	12	26.67	98	0	0.00	64	29	31.18
ARHGEF17	0	genome.wustl.edu	37	11	73021059	73021059	+	Missense_Mutation	SNP	G	G	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	11	73021059	73021059	G	T	SNP	ARHGEF17	ENST00000263674	human	ensembl	74_37	+1	known	missense	c.1376	p.R459L	0.936	NULL	pfam_DH-domain,superfamily_DH-domain,superfamily_WD40_repeat_dom,superfamily_Vinculin/catenin,smart_DH-domain,pfscan_DH-domain	-	no_errors	ARHGEF17	HGNC	ENSG00000110237	tier1	-	-	31	0	0.00	9	11	55.00	77	0	0.00	7	49	87.50
DLK2	0	genome.wustl.edu	37	6	43420846	43420846	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	6	43420846	43420846	G	C	SNP	DLK2	ENST00000357338	human	ensembl	74_37	-1	known	missense	c.168	p.H56Q	1.000	smart_EG-like_dom,pfscan_EG-like_dom	pfam_EG-like_dom,pfam_EGF_extracell,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom	-	no_errors	DLK2	HGNC	ENSG00000171462	tier1	-	-	23	0	0.00	4	11	73.33	22	0	0.00	4	8	66.67
LRRC20	0	genome.wustl.edu	37	10	72083656	72083656	+	Silent	SNP	C	C	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	10	72083656	72083656	C	A	SNP	LRRC20	ENST00000355790	human	ensembl	74_37	-1	known	silent	c.363	p.A121	0.006	smart_Leu-rich_rpt_typical-subtyp	pfam_Leu-rich_rpt,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	LRRC20	HGNC	ENSG00000172731	tier1	-	-	31	0	0.00	9	13	59.09	56	0	0.00	4	17	80.95
CDH9	0	genome.wustl.edu	37	5	26890055	26890055	+	Missense_Mutation	SNP	G	G	C			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	5	26890055	26890055	G	C	SNP	CDH9	ENST00000231021	human	ensembl	74_37	-1	known	missense	c.1402	p.Q468E	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Cadherin_cytoplasmic-dom,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	CDH9	HGNC	ENSG00000113100	tier1	-	-	63	0	0.00	96	10	9.43	119	0	0.00	214	21	8.90
PHYHIP	0	genome.wustl.edu	37	8	22079106	22079106	+	Silent	SNP	G	G	A			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	8	22079106	22079106	G	A	SNP	PHYHIP	ENST00000454243	human	ensembl	74_37	-1	known	silent	c.753	p.R251	0.060	NULL	superfamily_Fibronectin_type3,pfscan_Fibronectin_type3	-	no_errors	PHYHIP	HGNC	ENSG00000168490	tier1	rs112627300	GMAF=0.0005	36	0	0.00	20	6	23.08	19	1	5.00	19	17	47.22
ENSG00000221121	0	genome.wustl.edu	37	12	82736380	82736385	+	R	DEL	ATATAC	ATATAC	-			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	ATATAC	ATATAC					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	12	82736380	82736385	ATATAC	-	DEL	ENSG00000221121	ENST00000408194	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.012:0.010:0.008:0.005:0.002:0.001	-	-	-	no_errors	AC083811.1	Clone_based_ensembl_gene	ENSG00000221121	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
LOC644794	0	genome.wustl.edu	37	7	66369212	66369213	+	R	INS	-	-	GGCCTTTCCAGGCCCAGCTCTCGCCTCCCGGC			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	7	66369212	66369213	-	GGCCTTTCCAGGCCCAGCTCTCGCCTCCCGGC	INS	LOC644794	ENST00000610177	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.293:0.454	-	-	-	no_errors	RP11-458F8.4	Clone_based_vega_gene	ENSG00000273142	tier1			0	0	0.00	1	0	0.00	0	0	0.00	1	0	0.00
NRXN1	0	genome.wustl.edu	37	2	50147836	50147853	+	R	DEL	GTGTGTGTGTGTGTGTGT	GTGTGTGTGTGTGTGTGT	-			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	GTGTGTGTGTGTGTGTGT	GTGTGTGTGTGTGTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	2	50147836	50147853	GTGTGTGTGTGTGTGTGT	-	DEL	NRXN1	ENST00000484192	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.001:0.005:0.106:0.113:0.127:0.107:0.109:0.093:0.096:0.025:0.055:0.070:0.324:0.354:0.283:0.295:0.258	-	-	-	no_errors	NRXN1	HGNC	ENSG00000179915	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
R5-8SP6	0	genome.wustl.edu	37	Y	10037843	10037843	+	R	SNP	C	C	T			TCGA-HB-A5W3-01A-11D-A29N-09	TCGA-HB-A5W3-10A-01D-A29N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4d4eff82-ede0-47f1-b49a-ada025952114	546cfd48-e472-4186-a83a-09f5aef53000	Y	10037843	10037843	C	T	SNP	R5-8SP6	ENST00000515896	human	ensembl	74_37	+1	known	rna	NULL	NULL	1.000	-	-	-	no_errors	R5-8SP6	HGNC	ENSG00000251705	tier1	-	-	64	0	0.00	50	5	9.09	2	0	0.00	1	0	0.00