Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TTBK2	0	genome.wustl.edu	37	15	43045133	43045133	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	15	43045133	43045133	C	G	SNP	TTBK2	ENST00000267890	human	ensembl	74_37	-1	known	missense	c.2311	p.E771Q	0.997	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TTBK2	HGNC	ENSG00000128881	tier1	-	-	62	0	0.00	42	31	42.47	109	0	0.00	49	59	54.63
DH17	0	genome.wustl.edu	37	17	76446859	76446859	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	17	76446859	76446859	G	A	SNP	DH17	ENST00000389840	human	ensembl	74_37	-1	known	missense	c.10762	p.R3588C	1.000	superfamily_P-loop_NTPase	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-1,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,superfamily_HR1_rho-bd	-	no_errors	DH17	HGNC	ENSG00000187775	tier1	-	-	62	0	0.00	27	24	47.06	72	0	0.00	43	36	45.57
TTBK2	0	genome.wustl.edu	37	15	43044957	43044957	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	15	43044957	43044957	C	T	SNP	TTBK2	ENST00000267890	human	ensembl	74_37	-1	known	silent	c.2487	p.Q829	1.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	TTBK2	HGNC	ENSG00000128881	tier1	-	-	46	0	0.00	25	29	53.70	115	0	0.00	57	35	38.04
WDFY4	0	genome.wustl.edu	37	10	49951200	49951200	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951200	49951200	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	missense	c.2066	p.S689F	0.991	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	63	0	0.00	88	14	13.73	72	0	0.00	64	24	27.27
CUX1	0	genome.wustl.edu	37	7	101801856	101801856	+	Missense_Mutation	SNP	A	A	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	101801856	101801856	A	T	SNP	CUX1	ENST00000360264	human	ensembl	74_37	+1	known	missense	c.724	p.M242L	1.000	NULL	pfam_Hmoeo_CUT,pfam_Homeobox_dom,superfamily_Lambda_D-bd_dom,superfamily_Homeodomain-like,superfamily_LemA-like_dom,smart_Homeobox_dom,pfscan_Homeobox_dom,pfscan_Hmoeo_CUT	-	no_errors	CUX1	HGNC	ENSG00000257923	tier1	-	-	57	0	0.00	24	24	50.00	68	0	0.00	56	31	35.63
ASTN1	0	genome.wustl.edu	37	1	177001821	177001821	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	177001821	177001821	G	A	SNP	ASTN1	ENST00000367654	human	ensembl	74_37	-1	known	silent	c.636	p.H212	0.099	NULL	superfamily_Fibronectin_type3,smart_EG-like_dom,smart_MACPF,pfscan_Fibronectin_type3	-	no_errors	ASTN1	HGNC	ENSG00000152092	tier1	-	-	52	0	0.00	45	22	32.84	24	0	0.00	21	8	27.59
HNF1B	0	genome.wustl.edu	37	17	36091772	36091772	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	17	36091772	36091772	C	G	SNP	HNF1B	ENST00000225893	human	ensembl	74_37	-1	known	missense	c.859	p.G287R	1.000	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Homeobox_dom,pfscan_Homeobox_dom	pfam_HNF1b_C,pfam_HNF-1_N,pfam_Homeobox_dom,superfamily_Lambda_D-bd_dom,superfamily_Homeodomain-like,superfamily_HNF1_dimer_dom,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	HNF1B	HGNC	ENSG00000108753	tier1	-	-	34	0	0.00	15	20	57.14	81	0	0.00	23	30	56.60
ADAM28	0	genome.wustl.edu	37	8	24168921	24168921	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	24168921	24168921	C	T	SNP	ADAM28	ENST00000265769	human	ensembl	74_37	+1	known	silent	c.354	p.D118	0.730	pfam_Peptidase_M12B_N	pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_Cys-rich,pfam_Blood-coag_inhib_Disintegrin,superfamily_Blood-coag_inhib_Disintegrin,smart_Blood-coag_inhib_Disintegrin,smart_ADAM_Cys-rich,pfscan_Blood-coag_inhib_Disintegrin,pfscan_EG-like_dom,pfscan_Peptidase_M12B,prints_Blood-coag_inhib_Disintegrin	-	no_errors	ADAM28	HGNC	ENSG00000042980	tier1	rs144018592	-	64	0	0.00	61	22	26.51	98	0	0.00	56	14	20.00
TSPAN6	0	genome.wustl.edu	37	X	99890554	99890554	+	Splice_Site	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	X	99890554	99890554	C	A	SNP	TSPAN6	ENST00000373020	human	ensembl	74_37	-1	known	splice_site	c.276+1	e2+1	1.000	-	-	-	no_errors	TSPAN6	HGNC	ENSG00000000003	tier1	-	-	41	0	0.00	18	4	18.18	112	1	0.88	34	5	12.82
WDFY4	0	genome.wustl.edu	37	10	49951225	49951225	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951225	49951225	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2091	p.V697	1.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	53	0	0.00	87	15	14.71	71	0	0.00	70	28	28.57
WDFY4	0	genome.wustl.edu	37	10	49951426	49951426	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951426	49951426	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2292	p.L764	0.014	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	42	0	0.00	87	20	18.69	94	0	0.00	93	23	19.66
WDFY4	0	genome.wustl.edu	37	10	49951403	49951403	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951403	49951403	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	missense	c.2269	p.P757S	1.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	42	0	0.00	74	16	17.78	85	0	0.00	85	19	18.27
TCTN1	0	genome.wustl.edu	37	12	111065921	111065921	+	Silent	SNP	A	A	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	111065921	111065921	A	G	SNP	TCTN1	ENST00000397656	human	ensembl	74_37	+1	known	silent	c.537	p.P179	0.000	NULL	pfam_DUF1619	-	no_errors	TCTN1	HGNC	ENSG00000204852	tier1	-	-	53	0	0.00	19	25	56.82	53	0	0.00	34	17	33.33
LOC100507600	0	genome.wustl.edu	37	2	136579728	136579728	+	R	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	2	136579728	136579728	G	A	SNP	LOC100507600	ENST00000437007	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.002	-	-	-	no_errors	AC011893.3	Clone_based_vega_gene	ENSG00000226806	tier1	-	-	28	0	0.00	19	7	26.92	101	1	0.98	76	22	22.45
DLGAP4	0	genome.wustl.edu	37	20	35075162	35075162	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	20	35075162	35075162	G	A	SNP	DLGAP4	ENST00000339266	human	ensembl	74_37	+1	known	silent	c.1470	p.A490	0.001	NULL	pfam_GKAP	-	no_errors	DLGAP4	HGNC	ENSG00000080845	tier1	-	-	86	0	0.00	28	23	45.10	21	0	0.00	11	3	21.43
TRPM3	0	genome.wustl.edu	37	9	73391377	73391377	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	9	73391377	73391377	C	G	SNP	TRPM3	ENST00000396283	human	ensembl	74_37	-1	putative	missense	c.791	p.R264T	0.004	NULL	NULL	-	no_errors	TRPM3	HGNC	ENSG00000083067	tier1	-	-	57	0	0.00	25	23	47.92	49	0	0.00	20	25	55.56
KIAA1429	0	genome.wustl.edu	37	8	95547168	95547168	+	Missense_Mutation	SNP	A	A	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	95547168	95547168	A	T	SNP	KIAA1429	ENST00000297591	human	ensembl	74_37	-1	known	missense	c.383	p.V128E	1.000	NULL	superfamily_ARM-type_fold	-	no_errors	KIAA1429	HGNC	ENSG00000164944	tier1	-	-	32	0	0.00	30	15	33.33	76	0	0.00	41	34	45.33
FBXO38	0	genome.wustl.edu	37	5	147806999	147806999	+	Missense_Mutation	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	147806999	147806999	C	G	SNP	FBXO38	ENST00000340253	human	ensembl	74_37	+1	known	missense	c.2142	p.N714K	0.980	NULL	superfamily_F-box_dom	-	no_errors	FBXO38	HGNC	ENSG00000145868	tier1	-	-	10	0	0.00	10	6	37.50	51	1	1.92	23	20	46.51
HMGCLL1	0	genome.wustl.edu	37	6	55406543	55406543	+	Missense_Mutation	SNP	G	G	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	55406543	55406543	G	C	SNP	HMGCLL1	ENST00000398661	human	ensembl	74_37	-1	known	missense	c.371	p.S124C	1.000	pfam_PYR_CT,pfscan_PYR_CT	pfam_PYR_CT,pfscan_PYR_CT	-	no_errors	HMGCLL1	HGNC	ENSG00000146151	tier1	-	-	69	0	0.00	41	49	54.44	74	0	0.00	67	49	42.24
KNTC1	0	genome.wustl.edu	37	12	123070191	123070191	+	Silent	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	123070191	123070191	T	C	SNP	KNTC1	ENST00000333479	human	ensembl	74_37	+1	known	silent	c.3543	p.F1181	0.989	NULL	pfam_RZZ-complex_KNTC1/ROD_C,superfamily_Quino_amine_DH_bsu,superfamily_WD40_repeat_dom,superfamily_PAH	-	no_errors	KNTC1	HGNC	ENSG00000184445	tier1	-	-	92	0	0.00	56	35	38.46	83	0	0.00	31	33	51.56
KLC4	0	genome.wustl.edu	37	6	43041689	43041689	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	43041689	43041689	G	A	SNP	KLC4	ENST00000259708	human	ensembl	74_37	+1	known	missense	c.1849	p.A617T	0.909	NULL	pfam_Rabaptin_Rab5-bd_dom,pfam_TPR_1,smart_TPR_repeat,pfscan_TPR_repeat,pfscan_TPR-contain_dom,prints_Kinesin_light	-	no_errors	KLC4	HGNC	ENSG00000137171	tier1	-	-	127	0	0.00	76	41	34.75	109	0	0.00	60	22	26.83
GPRIN3	0	genome.wustl.edu	37	4	90168982	90168982	+	Missense_Mutation	SNP	G	G	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	4	90168982	90168982	G	C	SNP	GPRIN3	ENST00000333209	human	ensembl	74_37	-1	known	missense	c.2280	p.F760L	0.015	NULL	NULL	-	no_errors	GPRIN3	HGNC	ENSG00000185477	tier1	-	-	46	0	0.00	26	28	51.85	60	0	0.00	29	13	30.95
HSD17B12	0	genome.wustl.edu	37	11	43819959	43819959	+	Missense_Mutation	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	43819959	43819959	C	T	SNP	HSD17B12	ENST00000278353	human	ensembl	74_37	+1	known	missense	c.373	p.L125F	0.999	pfam_DH_sc/Rdtase_SDR,prints_Glc/ribitol_DH,prints_DH_sc/Rdtase_SDR	pfam_DH_sc/Rdtase_SDR,prints_Glc/ribitol_DH,prints_DH_sc/Rdtase_SDR	-	no_errors	HSD17B12	HGNC	ENSG00000149084	tier1	-	-	47	0	0.00	18	13	41.94	66	0	0.00	53	29	35.37
WDFY4	0	genome.wustl.edu	37	10	49951504	49951504	+	Silent	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	49951504	49951504	C	T	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	silent	c.2370	p.T790	0.000	superfamily_ARM-type_fold	pfam_BEACH_dom,pfam_WD40_repeat,superfamily_BEACH_dom,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,smart_WD40_repeat,pfscan_BEACH_dom,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	39	0	0.00	60	18	23.08	93	0	0.00	118	30	20.27
GLI1	0	genome.wustl.edu	37	12	57864284	57864284	+	Nonsense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	57864284	57864284	C	A	SNP	GLI1	ENST00000228682	human	ensembl	74_37	+1	known	nonsense	c.1761	p.Y587*	1.000	NULL	smart_Znf_C2H2-like,pfscan_Znf_C2H2	-	no_errors	GLI1	HGNC	ENSG00000111087	tier1	-	-	60	0	0.00	34	16	32.00	50	0	0.00	13	14	51.85
OR10S1	0	genome.wustl.edu	37	11	123847411	123847411	+	Missense_Mutation	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	123847411	123847411	G	T	SNP	OR10S1	ENST00000531945	human	ensembl	74_37	-1	known	missense	c.988	p.P330T	0.014	NULL	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR10S1	HGNC	ENSG00000196248	tier1	-	-	16	0	0.00	17	7	29.17	41	0	0.00	39	27	40.91
SLC24A4	0	genome.wustl.edu	37	14	92923649	92923650	+	R	INS	-	-	ACACCAGG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-	-	ACACCAGG	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	14	92923649	92923650	-	ACACCAGG	INS	SLC24A4	ENST00000556739	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	SLC24A4	HGNC	ENSG00000140090	tier1			44	0	0.00	17	2	10.53	44	0	0.00	17	2	10.53
ACTA2	0	genome.wustl.edu	37	10	90701022	90701025	+	Frame_Shift_Del	DEL	TCTT	TCTT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCTT	TCTT	TCTT	-	TCTT	TCTT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	90701022	90701025	TCTT	-	DEL	ACTA2	ENST00000224784	human	ensembl	74_37	-1	known	frame_shift_del	c.580_577	p.K193fs	1.000:1.000:1.000:1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTA2	HGNC	ENSG00000107796	tier1			75	0	0.00	10	26	72.22	36	0	0.00	6	18	75.00
ACTA2	0	genome.wustl.edu	37	10	90701026	90701026	+	Missense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	90701026	90701026	C	A	SNP	ACTA2	ENST00000224784	human	ensembl	74_37	-1	known	missense	c.576	p.M192I	1.000	pfam_Actin-related,smart_Actin-related	pfam_Actin-related,smart_Actin-related,prints_Actin-related	-	no_errors	ACTA2	HGNC	ENSG00000107796	tier1	-	-	73	0	0.00	9	30	76.92	36	0	0.00	6	18	75.00
ADAMTS18	0	genome.wustl.edu	37	16	77325184	77325184	+	Missense_Mutation	SNP	C	C	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	77325184	77325184	C	A	SNP	ADAMTS18	ENST00000282849	human	ensembl	74_37	-1	known	missense	c.3381	p.W1127C	1.000	superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS18	HGNC	ENSG00000140873	tier1	-	-	72	0	0.00	11	21	65.62	86	0	0.00	6	36	85.71
ANGPTL3	0	genome.wustl.edu	37	1	63070097	63070097	+	R	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	63070097	63070097	C	T	SNP	ANGPTL3	ENST00000493994	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.000	-	-	-	no_errors	ANGPTL3	HGNC	ENSG00000132855	tier1	-	-	14	0	0.00	5	4	44.44	59	0	0.00	3	44	93.62
ELFN2	0	genome.wustl.edu	37	22	37770666	37770666	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	22	37770666	37770666	G	A	SNP	ELFN2	ENST00000402918	human	ensembl	74_37	-1	known	silent	c.909	p.H303	0.337	superfamily_Fibronectin_type3	superfamily_Fibronectin_type3,smart_Leu-rich_rpt_typical-subtyp,pfscan_LPXTG_anchor	-	no_errors	ELFN2	HGNC	ENSG00000166897	tier1	rs201226596	-	94	0	0.00	14	45	76.27	31	0	0.00	3	13	81.25
EMP2	0	genome.wustl.edu	37	16	10625606	10625613	+	R	DEL	ATGAATGA	ATGAATGA	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	ATGAATGA	ATGAATGA	ATGAATGA	-	ATGAATGA	ATGAATGA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	10625606	10625613	ATGAATGA	-	DEL	EMP2	ENST00000566033	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.092:0.092:0.091:0.090:0.088:0.085:0.082:0.078	-	-	-	no_errors	EMP2	HGNC	ENSG00000213853	tier1			6	0	0.00	6	2	25.00	6	0	0.00	6	2	25.00
GATC	0	genome.wustl.edu	37	12	120884319	120884319	+	Silent	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884319	120884319	C	G	SNP	GATC	ENST00000551765	human	ensembl	74_37	+1	known	silent	c.36	p.A12	0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1	-	-	110	0	0.00	62	20	24.39	18	0	0.00	4	4	50.00
GATC	0	genome.wustl.edu	37	12	120884322	120884331	+	Frame_Shift_Del	DEL	TCTGGGCGGG	TCTGGGCGGG	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TCTGGGCGGG	TCTGGGCGGG	TCTGGGCGGG	-	TCTGGGCGGG	TCTGGGCGGG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884322	120884331	TCTGGGCGGG	-	DEL	GATC	ENST00000551765	human	ensembl	74_37	+1	known	frame_shift_del	c.39_48	p.L14fs	0.000:0.000:0.000:0.001:0.000:0.000:0.000:0.000:0.000:0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1			15	0	0.00	4	4	50.00	15	0	0.00	4	4	50.00
MRGPRX3	0	genome.wustl.edu	37	11	18159001	18159001	+	Silent	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	18159001	18159001	G	A	SNP	MRGPRX3	ENST00000396275	human	ensembl	74_37	+1	known	silent	c.252	p.P84	0.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	MRGPRX3	HGNC	ENSG00000179826	tier1	rs148328055	-	57	0	0.00	12	25	67.57	45	0	0.00	6	16	72.73
MUC2	0	genome.wustl.edu	37	11	1098687	1098687	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	11	1098687	1098687	G	A	SNP	MUC2	ENST00000441003	human	ensembl	74_37	+1	known	missense	c.7057	p.D2353N	0.118	pfam_Unchr_dom_Cys-rich,smart_Unchr_dom_Cys-rich	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_TIL_dom,superfamily_TIL_dom,superfamily_Prot_inh_PMP,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_VWC_out,smart_VWF_C,smart_Cys_knot_C,pfscan_Cys_knot_C,pfscan_VWF_C	-	no_errors	MUC2	HGNC	ENSG00000198788	tier1	-	-	112	0	0.00	10	54	84.38	15	0	0.00	3	3	50.00
SLC17A4	0	genome.wustl.edu	37	6	25771211	25771211	+	Missense_Mutation	SNP	T	T	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	6	25771211	25771211	T	A	SNP	SLC17A4	ENST00000377905	human	ensembl	74_37	+1	known	missense	c.677	p.I226K	0.004	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom	-	no_errors	SLC17A4	HGNC	ENSG00000146039	tier1	-	-	128	0	0.00	6	43	87.76	83	0	0.00	4	26	86.67
TM2D1	0	genome.wustl.edu	37	1	62190776	62190776	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	62190776	62190776	G	A	SNP	TM2D1	ENST00000371180	human	ensembl	74_37	-1	known	missense	c.203	p.P68L	0.004	NULL	pfam_TM2	-	no_errors	TM2D1	HGNC	ENSG00000162604	tier1	-	-	56	0	0.00	5	24	82.76	18	0	0.00	1	5	83.33
UBAC2	0	genome.wustl.edu	37	13	100038221	100038221	+	R	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	13	100038221	100038221	C	G	SNP	UBAC2	ENST00000460562	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.685	-	-	-	no_errors	UBAC2	HGNC	ENSG00000134882	tier1	-	-	12	0	0.00	3	8	72.73	36	0	0.00	0	24	100.00
WDR11	0	genome.wustl.edu	37	10	122648750	122648751	+	R	INS	-	-	TTTTGTTTTG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-	-	TTTTGTTTTG	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	122648750	122648751	-	TTTTGTTTTG	INS	WDR11	ENST00000604509	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.024:0.006	-	-	-	no_errors	WDR11	HGNC	ENSG00000120008	tier1			12	0	0.00	8	2	20.00	12	0	0.00	8	2	20.00
ARFGEF1	0	genome.wustl.edu	37	8	68188215	68188215	+	Missense_Mutation	SNP	G	G	A			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	8	68188215	68188215	G	A	SNP	ARFGEF1	ENST00000262215	human	ensembl	74_37	-1	known	missense	c.1333	p.P445S	1.000	superfamily_ARM-type_fold	pfam_Sec7_dom,pfam_DUF1981_Sec7_assoc,superfamily_Sec7_dom,superfamily_ARM-type_fold,smart_Sec7_dom,pfscan_Sec7_dom	-	no_errors	ARFGEF1	HGNC	ENSG00000066777	tier1	-	-	58	0	0.00	54	8	12.90	105	0	0.00	97	9	8.49
GATC	0	genome.wustl.edu	37	12	120884315	120884324	+	Frame_Shift_Del	DEL	GGGCCCCTCT	GGGCCCCTCT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	GGGCCCCTCT	GGGCCCCTCT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	12	120884315	120884324	GGGCCCCTCT	-	DEL	GATC	ENST00000551765	human	ensembl	74_37	+1	known	frame_shift_del	c.32_41	p.P13fs	0.002:0.002:0.000:0.000:0.000:0.000:0.000:0.000:0.000:0.000	NULL	pfam_Asp/Glu-ADT_csu,tigrfam_Asp/Glu-ADT_csu	-	no_errors	GATC	HGNC	ENSG00000257218	tier1			17	0	0.00	8	0	0.00	17	0	0.00	8	0	0.00
MIR3177	0	genome.wustl.edu	37	16	1785034	1785034	+	R	SNP	C	C	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	1785034	1785034	C	T	SNP	MIR3177	ENST00000578255	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR3177	HGNC	ENSG00000265820	tier1	-	-	24	0	0.00	25	17	40.48	11	0	0.00	5	0	0.00
ENSG00000221732	0	genome.wustl.edu	37	7	140280130	140280130	+	R	SNP	T	T	C			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	7	140280130	140280130	T	C	SNP	ENSG00000221732	ENST00000408805	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.057	-	-	-	no_errors	AC006452.1	Clone_based_ensembl_gene	ENSG00000221732	tier1	rs62485838	-	16	0	0.00	15	5	25.00	0	0	0.00	0	0	0.00
FOXA2	0	genome.wustl.edu	37	20	22562842	22562842	+	Silent	SNP	C	C	G			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	20	22562842	22562842	C	G	SNP	FOXA2	ENST00000419308	human	ensembl	74_37	-1	known	silent	c.1038	p.G346	0.997	NULL	pfam_TF_fork_head,pfam_Fork-head_N,pfam_Forkhead_box_C,smart_TF_fork_head,pfscan_TF_fork_head,prints_TF_fork_head	-	no_errors	FOXA2	HGNC	ENSG00000125798	tier1	-	-	8	0	0.00	5	4	44.44	0	0	0.00	0	0	0.00
IL21R-AS1	0	genome.wustl.edu	37	16	27459684	27459684	+	R	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	16	27459684	27459684	G	T	SNP	IL21R-AS1	ENST00000563191	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.004	-	-	-	no_errors	IL21R-AS1	HGNC	ENSG00000259954	tier1	-	-	13	0	0.00	5	8	61.54	0	0	0.00	0	0	0.00
LOR	0	genome.wustl.edu	37	1	153233991	153233992	+	In_Frame_Ins	INS	-	-	CTCTGGCGGCGG			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	1	153233991	153233992	-	CTCTGGCGGCGG	INS	LOR	ENST00000368742	human	ensembl	74_37	+1	known	in_frame_ins	c.566_567	p.193in_frame_insGSGG	0.014:0.200	NULL	NULL	-	no_errors	LOR	HGNC	ENSG00000203782	tier1			1	0	0.00	0	0	0.00	1	0	0.00	0	0	0.00
MSH3	0	genome.wustl.edu	37	5	79950712	79950738	+	In_Frame_Del	DEL	GCGGCCGCAGCGGCCGCAGCGCCCCCA	GCGGCCGCAGCGGCCGCAGCGCCCCCA	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	GCGGCCGCAGCGGCCGCAGCGCCCCCA	GCGGCCGCAGCGGCCGCAGCGCCCCCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	5	79950712	79950738	GCGGCCGCAGCGGCCGCAGCGCCCCCA	-	DEL	MSH3	ENST00000265081	human	ensembl	74_37	+1	known	in_frame_del	c.166_192	p.AAAAAAPPA57in_frame_del	0.238:0.205:0.172:0.140:0.107:0.075:0.032:0.035:0.048:0.057:0.087:0.730:0.747:0.894:0.911:0.915:0.941:0.965:0.997:1.000:1.000:1.000:1.000:0.988:0.984:0.963:0.965	NULL	pfam_D_mismatch_repair_MutS_C,pfam_D_mismatch_repair_MutS_core,pfam_D_mmatch_repair_MutS_con_dom,pfam_D_mismatch_repair_MutS-lik_N,pfam_D_mismatch_repair_MutS_clamp,superfamily_D_mismatch_repair_MutS_core,superfamily_P-loop_NTPase,superfamily_D_mismatch_repair_MutS_N,superfamily_D_mmatch_repair_MutS_con_dom,smart_D_mismatch_repair_MutS_core,smart_D_mismatch_repair_MutS_C	-	no_errors	MSH3	HGNC	ENSG00000113318	tier1			0	0	0.00	2	0	0.00	0	0	0.00	2	0	0.00
NUMBL	0	genome.wustl.edu	37	19	41173893	41173898	+	In_Frame_Del	DEL	TGCTGT	TGCTGT	-			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	TGCTGT	TGCTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	19	41173893	41173898	TGCTGT	-	DEL	NUMBL	ENST00000252891	human	ensembl	74_37	-1	known	in_frame_del	c.1310_1305	p.QQ439in_frame_del	1.000:1.000:1.000:1.000:1.000:0.998	pirsf_Numb/numb-like	pfam_Numb_domain,pfam_PTB/PI_dom,pfam_PTB,smart_PTB/PI_dom,pirsf_Numb/numb-like,pfscan_PTB/PI_dom	-	no_errors	NUMBL	HGNC	ENSG00000105245	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
GPR125	0	genome.wustl.edu	37	4	22404357	22404357	+	Silent	SNP	G	G	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	4	22404357	22404357	G	T	SNP	GPR125	ENST00000334304	human	ensembl	74_37	-1	known	silent	c.2298	p.T766	0.819	pfam_GPCR_2_secretin-like,pfscan_GPCR_2-like	pfam_GPCR_2_secretin-like,pfam_GPS_dom,pfam_Leu-rich_rpt,pfam_Ig_I-set,pfam_GPCR_2_extracellular_dom,smart_Leu-rich_rpt_typical-subtyp,smart_Cys-rich_flank_reg_C,smart_Ig_sub,smart_GPS_dom,pfscan_GPS_dom,pfscan_GPCR_2_extracellular_dom,pfscan_GPCR_2-like,pfscan_Ig-like_dom	-	no_errors	GPR125	HGNC	ENSG00000152990	tier1	-	-	51	0	0.00	32	4	11.11	123	0	0.00	124	2	1.59
ENSG00000200294	0	genome.wustl.edu	37	10	73940732	73940733	+	R	INS	-	-	T			TCGA-FX-A48G-01A-11D-A24N-09	TCGA-FX-A48G-11A-12D-A24N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	cb5e1546-cda6-4991-911c-f3dd9f1a475a	9ff2246f-8c56-445f-b2d9-aeeff5ce527a	10	73940732	73940733	-	T	INS	ENSG00000200294	ENST00000363424	human	ensembl	74_37	+1	novel	rna	NULL	NULL	0.371:0.371	-	-	-	no_errors	SNORA36	RFAM	ENSG00000200294	tier1			13	0	0.00	7	3	30.00	49	0	0.00	25	2	7.41