Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
FRG2B	0	genome.wustl.edu	37	10	135438937	135438937	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	10	135438937	135438937	G	A	SNP	FRG2B	ENST00000425520	human	ensembl	74_37	-1	known	missense	c.503	p.T168I	0.147	NULL	NULL	-	no_errors	FRG2B	HGNC	ENSG00000225899	tier1	-	-	97	0	0.00	100	38	27.54	104	0	0.00	45	16	26.23
LOXHD1	0	genome.wustl.edu	37	18	44114401	44114401	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	18	44114401	44114401	C	T	SNP	LOXHD1	ENST00000536736	human	ensembl	74_37	-1	known	missense	c.4109	p.G1370E	1.000	pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,pfscan_PLAT/LH2_dom	pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,pfscan_PLAT/LH2_dom	-	no_errors	LOXHD1	HGNC	ENSG00000167210	tier1	-	-	40	0	0.00	34	24	41.38	105	0	0.00	57	33	36.67
GPRIN3	0	genome.wustl.edu	37	4	90169946	90169946	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	4	90169946	90169946	C	G	SNP	GPRIN3	ENST00000333209	human	ensembl	74_37	-1	known	missense	c.1316	p.R439T	0.000	NULL	NULL	-	no_errors	GPRIN3	HGNC	ENSG00000185477	tier1	-	-	22	0	0.00	27	12	30.77	89	0	0.00	43	21	32.81
IRGC	0	genome.wustl.edu	37	19	44223484	44223484	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	19	44223484	44223484	G	C	SNP	IRGC	ENST00000244314	human	ensembl	74_37	+1	known	missense	c.774	p.K258N	1.000	pfam_Interferon-induced_GTPase,superfamily_P-loop_NTPase	pfam_Interferon-induced_GTPase,superfamily_P-loop_NTPase	-	no_errors	IRGC	HGNC	ENSG00000124449	tier1	-	-	22	0	0.00	13	41	75.93	37	0	0.00	11	11	50.00
GLYATL1	0	genome.wustl.edu	37	11	58722681	58722681	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	58722681	58722681	G	T	SNP	GLYATL1	ENST00000300079	human	ensembl	74_37	+1	known	missense	c.439	p.V147L	0.000	pfam_Glycine_N-acyltransferase_N,superfamily_Acyl_CoA_acyltransferase	pfam_Glycine_N-acyltransferase_N,pfam_Glycine_N-acyltransferase_C,superfamily_Acyl_CoA_acyltransferase	-	no_errors	GLYATL1	HGNC	ENSG00000166840	tier1	-	-	63	0	0.00	56	16	22.22	35	0	0.00	23	13	36.11
CD48	0	genome.wustl.edu	37	1	160651093	160651093	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	1	160651093	160651093	G	A	SNP	CD48	ENST00000368046	human	ensembl	74_37	-1	known	missense	c.551	p.T184I	0.000	pfscan_Ig-like_dom	pfam_Ig_V-set,smart_Ig_sub,pfscan_Ig-like_dom	-	no_errors	CD48	HGNC	ENSG00000117091	tier1	-	-	69	0	0.00	133	25	15.82	111	0	0.00	147	31	17.42
VPS13C	0	genome.wustl.edu	37	15	62261524	62261524	+	Missense_Mutation	SNP	A	A	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	15	62261524	62261524	A	C	SNP	VPS13C	ENST00000261517	human	ensembl	74_37	-1	known	missense	c.2885	p.I962S	1.000	NULL	pfam_VPSAP_dom,pfam_Autophagy-rel_C	-	no_errors	VPS13C	HGNC	ENSG00000129003	tier1	-	-	39	0	0.00	37	41	52.56	76	0	0.00	41	59	59.00
MCCC1-AS1	0	genome.wustl.edu	37	3	182735048	182735048	+	R	SNP	C	C	G			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	3	182735048	182735048	C	G	SNP	MCCC1-AS1	ENST00000471731	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.104	-	-	-	no_errors	MCCC1-AS1	HGNC	ENSG00000243368	tier1	-	-	43	0	0.00	43	18	29.51	102	0	0.00	84	65	43.62
DERL1	0	genome.wustl.edu	37	8	124031520	124031520	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	8	124031520	124031520	G	C	SNP	DERL1	ENST00000259512	human	ensembl	74_37	-1	known	missense	c.532	p.L178V	1.000	pfam_DER1	pfam_DER1	-	no_errors	DERL1	HGNC	ENSG00000136986	tier1	-	-	27	0	0.00	30	7	18.92	85	0	0.00	65	22	25.29
ZNF215	0	genome.wustl.edu	37	11	6977273	6977273	+	Nonsense_Mutation	SNP	T	T	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	6977273	6977273	T	A	SNP	ZNF215	ENST00000278319	human	ensembl	74_37	+1	known	nonsense	c.1065	p.Y355*	0.013	NULL	pfam_Tscrpt_reg_SCAN,pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Retrov_capsid_C,superfamily_Krueppel-associated_box,smart_Tscrpt_reg_SCAN,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZNF215	HGNC	ENSG00000149054	tier1	-	-	13	0	0.00	13	9	40.91	100	0	0.00	39	21	35.00
FAT4	0	genome.wustl.edu	37	4	126328179	126328179	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	4	126328179	126328179	G	T	SNP	FAT4	ENST00000394329	human	ensembl	74_37	+1	known	missense	c.5452	p.D1818Y	1.000	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EG-like_dom,pfam_EGF-like_Ca-bd_dom,superfamily_Cadherin-like,superfamily_ConA-like_lec_gl_sf,smart_Cadherin,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Laminin_G,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT4	HGNC	ENSG00000196159	tier1	-	-	46	0	0.00	43	14	24.56	67	0	0.00	39	17	30.36
KCNH8	0	genome.wustl.edu	37	3	19556882	19556882	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	3	19556882	19556882	G	A	SNP	KCNH8	ENST00000328405	human	ensembl	74_37	+1	known	missense	c.2504	p.R835Q	0.970	NULL	pfam_Ion_trans_dom,pfam_cNMP-bd_dom,pfam_2pore_dom_K_chnl_dom,pfam_PAS_fold_3,pfam_PAS_4,pfam_PAS_fold,superfamily_cNMP-bd-like,superfamily_PAS,superfamily_tR-bd_arm,smart_PAC,smart_cNMP-bd_dom,pfscan_cNMP-bd_dom,pfscan_PAS-assoc_C,prints_K_chnl_volt-dep_EAG/ELK/ERG,prints_K_chnl_volt-dep_ELK,prints_K_chnl_volt-dep_ERG,prints_K_chnl_volt-dep_EAG,tigrfam_PAS	-	no_errors	KCNH8	HGNC	ENSG00000183960	tier1	-	-	48	0	0.00	26	15	36.59	94	0	0.00	38	20	34.48
UNC13C	0	genome.wustl.edu	37	15	54542514	54542514	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	15	54542514	54542514	C	T	SNP	UNC13C	ENST00000260323	human	ensembl	74_37	+1	known	missense	c.3320	p.T1107I	0.911	pfam_Prot_Kinase_C-like_PE/DAG-bd,smart_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_Kinase_C-like_PE/DAG-bd	pfam_Munc13_subgr_dom-2,pfam_Ca-dep_secretion_activator,pfam_C2_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,prints_C2_dom	-	no_errors	UNC13C	HGNC	ENSG00000137766	tier1	-	-	58	0	0.00	71	28	28.28	73	0	0.00	44	28	38.89
DCBLD2	0	genome.wustl.edu	37	3	98536625	98536625	+	Silent	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	3	98536625	98536625	C	T	SNP	DCBLD2	ENST00000326857	human	ensembl	74_37	-1	known	silent	c.1200	p.V400	0.999	pfam_Coagulation_fac_5/8-C_type_dom,superfamily_Galactose-bd-like,smart_Coagulation_fac_5/8-C_type_dom,pfscan_Coagulation_fac_5/8-C_type_dom	pfam_Coagulation_fac_5/8-C_type_dom,pfam_CUB_dom,pfam_LCCL,superfamily_Galactose-bd-like,superfamily_CUB_dom,superfamily_LCCL,smart_CUB_dom,smart_LCCL,smart_Coagulation_fac_5/8-C_type_dom,pfscan_CUB_dom,pfscan_Coagulation_fac_5/8-C_type_dom,pfscan_LCCL	-	no_errors	DCBLD2	HGNC	ENSG00000057019	tier1	-	-	63	0	0.00	76	22	22.45	52	1	1.89	39	5	11.36
FSTL5	0	genome.wustl.edu	37	4	162463768	162463768	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	4	162463768	162463768	C	G	SNP	FSTL5	ENST00000306100	human	ensembl	74_37	-1	known	missense	c.1093	p.E365Q	1.000	pfam_Ig_I-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Kazal_dom,pfam_Ig_V-set,smart_Kazal_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_EF_hand_dom,pfscan_Ig-like_dom	-	no_errors	FSTL5	HGNC	ENSG00000168843	tier1	-	-	32	0	0.00	31	19	38.00	80	0	0.00	33	16	32.65
RET	0	genome.wustl.edu	37	10	43615578	43615578	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	10	43615578	43615578	G	A	SNP	RET	ENST00000355710	human	ensembl	74_37	+1	known	missense	c.2657	p.R886Q	0.997	pirsf_Tyr_kinase_Ret_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pirsf_Tyr_kinase_Ret_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Cadherin,superfamily_Kinase-like_dom,superfamily_Cadherin-like,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Cadherin	-	no_errors	RET	HGNC	ENSG00000165731	tier1	-	-	59	0	0.00	29	18	38.30	95	0	0.00	33	11	25.00
COLEC12	0	genome.wustl.edu	37	18	357461	357461	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	18	357461	357461	G	C	SNP	COLEC12	ENST00000400256	human	ensembl	74_37	-1	known	missense	c.120	p.I40M	1.000	NULL	pfam_C-type_lectin,pfam_Collagen,superfamily_C-type_lectin_fold,smart_C-type_lectin,prints_AntifreezeII,pfscan_C-type_lectin	-	no_errors	COLEC12	HGNC	ENSG00000158270	tier1	-	-	29	0	0.00	65	21	24.42	85	0	0.00	132	15	10.14
ERVMER34-1	0	genome.wustl.edu	37	4	53611579	53611579	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	4	53611579	53611579	T	C	SNP	ERVMER34-1	ENST00000440542	human	ensembl	74_37	-1	known	missense	c.109	p.I37V	0.008	NULL	pfam_TLV/ENV_coat_polyprotein	-	no_errors	ERVMER34-1	HGNC	ENSG00000226887	tier1	-	-	37	0	0.00	57	9	13.64	79	0	0.00	69	27	28.12
MMP1	0	genome.wustl.edu	37	11	102666020	102666020	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	102666020	102666020	G	T	SNP	MMP1	ENST00000315274	human	ensembl	74_37	-1	known	missense	c.784	p.R262S	0.285	smart_Peptidase_Metallo,pirsf_Pept_M10A_Metazoans	pfam_Pept_M10_metallopeptidase,pfam_Hemopexin-like_repeat,pfam_Peptidoglycan-bd-like,superfamily_Hemopexin-like_dom,superfamily_Peptidoglycan-bd-like,smart_Peptidase_Metallo,smart_Hemopexin-like_repeat,pirsf_Pept_M10A_Metazoans,prints_Pept_M10A	-	no_errors	MMP1	HGNC	ENSG00000196611	tier1	rs12282811	GMAF=0.0005	9	0	0.00	7	15	68.18	127	0	0.00	44	33	42.86
ADAMTS17	0	genome.wustl.edu	37	15	100516423	100516423	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	15	100516423	100516423	G	A	SNP	ADAMTS17	ENST00000268070	human	ensembl	74_37	-1	known	missense	c.2954	p.S985L	1.000	pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_Thrombospondin_1_rpt,pfscan_Thrombospondin_1_rpt	pfam_Thrombospondin_1_rpt,pfam_Peptidase_M12B,pfam_Peptidase_M12B_N,pfam_ADAM_spacer1,pfam_PLAC,superfamily_Thrombospondin_1_rpt,smart_ADAM_Cys-rich,smart_Thrombospondin_1_rpt,pfscan_PLAC,pfscan_Thrombospondin_1_rpt,pfscan_Peptidase_M12B,prints_Peptidase_M12B_ADAM-TS	-	no_errors	ADAMTS17	HGNC	ENSG00000140470	tier1	-	-	23	0	0.00	55	50	47.62	26	0	0.00	29	14	32.56
MCCC1	0	genome.wustl.edu	37	3	182789076	182789076	+	Silent	SNP	T	T	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	3	182789076	182789076	T	A	SNP	MCCC1	ENST00000265594	human	ensembl	74_37	-1	known	silent	c.561	p.S187	0.238	pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_Dala_Dala_lig_C,pfam_ATP-grasp_carboxylate-amine,pfam_ATP-grasp_RimK-type,pfscan_ATP-grasp,pfscan_Biotin_carboxylation_dom	pfam_CbamoylP_synth_lsu-like_ATP-bd,pfam_CarbamoylP_synth_lsu_N,pfam_Biotin_COase_C,pfam_Biotin_lipoyl,pfam_Dala_Dala_lig_C,pfam_ATP-grasp_carboxylate-amine,pfam_ATP-grasp_RimK-type,pfam_ATP-grasp_DUF201-type,superfamily_PreATP-grasp_dom,superfamily_Rudment_hybrid_motif,superfamily_Single_hybrid_motif,smart_Biotin_COase_C,pfscan_ATP-grasp,pfscan_Biotin_carboxylation_dom,pfscan_Biotin_lipoyl	-	no_errors	MCCC1	HGNC	ENSG00000078070	tier1	-	-	46	0	0.00	45	16	26.23	122	0	0.00	91	19	17.27
DYNC2LI1	0	genome.wustl.edu	37	2	44028001	44028001	+	Silent	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	2	44028001	44028001	C	T	SNP	DYNC2LI1	ENST00000605786	human	ensembl	74_37	+1	known	silent	c.679	p.L227	0.987	NULL	pfam_Dynein_light_int_chain,superfamily_P-loop_NTPase	-	no_errors	DYNC2LI1	HGNC	ENSG00000138036	tier1	-	-	51	0	0.00	26	52	66.67	117	0	0.00	21	54	71.05
COL17A1	0	genome.wustl.edu	37	10	105798854	105798854	+	Silent	SNP	A	A	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	10	105798854	105798854	A	T	SNP	COL17A1	ENST00000353479	human	ensembl	74_37	-1	known	silent	c.2922	p.L974	0.973	NULL	pfam_Collagen	-	no_errors	COL17A1	HGNC	ENSG00000065618	tier1	-	-	32	0	0.00	40	6	13.04	133	0	0.00	90	19	17.27
RPGRIP1	0	genome.wustl.edu	37	14	21789428	21789428	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	14	21789428	21789428	C	T	SNP	RPGRIP1	ENST00000206660	human	ensembl	74_37	+1	known	missense	c.1478	p.P493L	0.030	NULL	pfam_DUF3250,superfamily_C2_dom	-	no_errors	RPGRIP1	HGNC	ENSG00000092200	tier1	-	-	57	0	0.00	112	21	15.79	117	1	0.85	103	29	21.64
ANKRD62	0	genome.wustl.edu	37	18	12125943	12125943	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	18	12125943	12125943	A	T	SNP	ANKRD62	ENST00000314074	human	ensembl	74_37	+1	known	missense	c.2081	p.K694I	0.133	NULL	pfam_Ankyrin_rpt,superfamily_Ankyrin_rpt-contain_dom,smart_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom	-	no_errors	ANKRD62	HGNC	ENSG00000181626	tier1	-	-	71	0	0.00	89	15	14.42	48	0	0.00	28	14	33.33
TMCO6	0	genome.wustl.edu	37	5	140024571	140024571	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	5	140024571	140024571	C	G	SNP	TMCO6	ENST00000252100	human	ensembl	74_37	+1	known	missense	c.1388	p.A463G	0.998	superfamily_ARM-type_fold	superfamily_ARM-type_fold,smart_Armadillo,pfscan_Importin-a_IBB	-	no_errors	TMCO6	HGNC	ENSG00000113119	tier1	-	-	22	0	0.00	19	9	32.14	49	0	0.00	42	16	27.59
PEX7	0	genome.wustl.edu	37	6	137147605	137147605	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	6	137147605	137147605	G	C	SNP	PEX7	ENST00000318471	human	ensembl	74_37	+1	known	missense	c.337	p.E113Q	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	PEX7	HGNC	ENSG00000112357	tier1	-	-	48	0	0.00	42	18	30.00	79	0	0.00	38	30	44.12
SCGB1D4	0	genome.wustl.edu	37	11	62066450	62066450	+	Silent	SNP	C	C	G			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	62066450	62066450	C	G	SNP	SCGB1D4	ENST00000358585	human	ensembl	74_37	-1	known	silent	c.33	p.S11	0.540	pfam_Secretoglobin	pfam_Secretoglobin,superfamily_Secretoglobin	-	no_errors	SCGB1D4	HGNC	ENSG00000197745	tier1	-	-	68	0	0.00	48	26	35.14	39	0	0.00	11	5	31.25
KCNQ1OT1	0	genome.wustl.edu	37	11	2683460	2683460	+	R	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	2683460	2683460	G	A	SNP	KCNQ1OT1	ENST00000597346	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	KCNQ1OT1	HGNC	ENSG00000269821	tier1	-	-	9	0	0.00	8	8	50.00	51	0	0.00	20	8	28.57
COL18A1	0	genome.wustl.edu	37	21	46888236	46888236	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	21	46888236	46888236	G	A	SNP	COL18A1	ENST00000359759	human	ensembl	74_37	+1	known	missense	c.1432	p.D478N	0.975	superfamily_ConA-like_lec_gl_sf,smart_Laminin_G	pfam_Collagenase_NC10/endostatin,pfam_DUF959_COL18_N,pfam_Collagen,pfam_Frizzled_dom,superfamily_C-type_lectin_fold,superfamily_ConA-like_lec_gl_sf,superfamily_Frizzled_dom,smart_Frizzled_dom,smart_Laminin_G,pfscan_Frizzled_dom	-	no_errors	COL18A1	HGNC	ENSG00000182871	tier1	-	-	49	0	0.00	54	13	19.40	31	0	0.00	20	11	35.48
F13A1	0	genome.wustl.edu	37	6	6174956	6174956	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	6	6174956	6174956	T	A	SNP	F13A1	ENST00000264870	human	ensembl	74_37	-1	known	missense	c.1604	p.K535M	1.000	pfam_Transglutaminase_C,superfamily_Transglutaminase_C	pfam_Transglutaminase_C,pfam_Transglutaminase_N,pfam_Transglutaminase-like,superfamily_Ig_E-set,superfamily_Transglutaminase_C,smart_Transglutaminase-like	-	no_errors	F13A1	HGNC	ENSG00000124491	tier1	-	-	118	0	0.00	92	38	29.23	156	0	0.00	68	32	32.00
ZNF106	0	genome.wustl.edu	37	15	42727686	42727686	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	15	42727686	42727686	G	T	SNP	ZNF106	ENST00000263805	human	ensembl	74_37	-1	known	missense	c.4708	p.H1570N	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_Znf_C2H2-like,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	ZNF106	HGNC	ENSG00000103994	tier1	-	-	33	0	0.00	31	32	50.79	116	0	0.00	73	75	50.68
USP24	0	genome.wustl.edu	37	1	55537558	55537559	+	Frame_Shift_Ins	INS	-	-	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	-	-	-	T	-	-	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	1	55537558	55537559	-	T	INS	USP24	ENST00000407756	human	ensembl	74_37	-1	known	frame_shift_ins	c.7249_7248	p.E2416fs	1.000:0.920	NULL	pfam_Peptidase_C19/C67,superfamily_UBA-like,superfamily_ARM-type_fold,pfscan_UBA/transl_elong_EF1B_N_euk,pfscan_Peptidase_C19/C67	-	no_errors	USP24	HGNC	ENSG00000162402	tier1			48	0	0.00	58	21	26.58	57	0	0.00	74	13	14.94
GAB	0	genome.wustl.edu	37	11	62414079	62414080	+	R	DEL	AG	AG	-			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	AG	AG	AG	-	AG	AG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	11	62414079	62414080	AG	-	DEL	GAB	ENST00000534419	human	ensembl	74_37	-1	known	rna	NULL	NULL	1.000:1.000	-	-	-	no_errors	GAB	HGNC	ENSG00000089597	tier1			58	0	0.00	56	15	21.13	33	0	0.00	11	4	26.67
CCDC157	0	genome.wustl.edu	37	22	30768185	30768185	+	Silent	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	22	30768185	30768185	G	A	SNP	CCDC157	ENST00000338306	human	ensembl	74_37	+1	known	silent	c.1245	p.R415	1.000	NULL	superfamily_Prefoldin,superfamily_t-SRE	-	no_errors	CCDC157	HGNC	ENSG00000187860	tier1	-	-	71	0	0.00	35	32	47.76	12	0	0.00	2	2	50.00
OR7E24	0	genome.wustl.edu	37	19	9362102	9362102	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	19	9362102	9362102	T	A	SNP	OR7E24	ENST00000456448	human	ensembl	74_37	+1	known	missense	c.383	p.M128K	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR7E24	HGNC	ENSG00000237521	tier1	-	-	106	1	0.93	98	61	38.36	10	0	0.00	3	4	57.14
SLC8A2	0	genome.wustl.edu	37	19	47941209	47941209	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	19	47941209	47941209	G	C	SNP	SLC8A2	ENST00000236877	human	ensembl	74_37	-1	known	missense	c.1907	p.T636R	0.924	tigrfam_Na_Ca_Ex	pfam_Calx_beta,pfam_NaCa_Exmemb,smart_Calx_beta,prints_Na_Ca_Ex,tigrfam_Na_Ca_Ex	-	no_errors	SLC8A2	HGNC	ENSG00000118160	tier1	-	-	22	0	0.00	3	12	80.00	84	0	0.00	8	18	69.23
CCNYL2	0	genome.wustl.edu	37	10	42924593	42924594	+	R	INS	-	-	C			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	10	42924593	42924594	-	C	INS	CCNYL2	ENST00000483242	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.996:0.999	-	-	-	no_errors	CCNYL2	HGNC	ENSG00000182632	tier1			101	1	0.98	16	3	15.79	14	0	0.00	0	0	0.00
CGB8	0	genome.wustl.edu	37	19	49551016	49551016	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	19	49551016	49551016	C	T	SNP	CGB8	ENST00000448456	human	ensembl	74_37	-1	known	missense	c.394	p.D132N	0.915	NULL	pfam_Cys_knot,smart_Gonadotropin_bsu	-	no_errors	CGB8	HGNC	ENSG00000213030	tier1	-	-	17	0	0.00	6	16	72.73	0	0	0.00	0	0	0.00
PBX2P1	0	genome.wustl.edu	37	3	142897185	142897202	+	R	DEL	TGTTTTTGTTGTTGTTGT	TGTTTTTGTTGTTGTTGT	-			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	TGTTTTTGTTGTTGTTGT	TGTTTTTGTTGTTGTTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	3	142897185	142897202	TGTTTTTGTTGTTGTTGT	-	DEL	PBX2P1	ENST00000560287	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.639:0.474:0.235:0.119:0.110:0.097:0.077:0.050:0.050:0.048:0.043:0.034:0.032:0.028:0.024:0.019:0.015:0.009	-	-	-	no_errors	PBX2P1	HGNC	ENSG00000244171	tier1			1	0	0.00	0	0	0.00	1	0	0.00	0	0	0.00
C19orf57	0	genome.wustl.edu	37	19	14000051	14000051	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A3U7-01A-11D-A29N-09	TCGA-DX-A3U7-10A-01D-A29N-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	9e7b51fb-2249-451a-bf23-bb2a3d935928	d4b86f75-b56f-404f-b88d-20adf47e17dd	19	14000051	14000051	G	A	SNP	C19orf57	ENST00000454313	human	ensembl	74_37	-1	known	nonsense	c.1618	p.Q540*	0.896	NULL	NULL	-	no_errors	C19orf57	HGNC	ENSG00000132016	tier1	-	-	48	0	0.00	68	14	17.07	38	0	0.00	25	2	7.41