Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
SLC39A5	0	genome.wustl.edu	37	12	56625110	56625110	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	56625110	56625110	G	A	SNP	SLC39A5	ENST00000266980	human	ensembl	74_37	+1	known	missense	c.52	p.V18I	0.011	NULL	pfam_ZIP	-	no_errors	SLC39A5	HGNC	ENSG00000139540	tier1	-	-	63	0	0.00	64	7	9.86	67	0	0.00	50	11	18.03
AQP6	0	genome.wustl.edu	37	12	50367325	50367325	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	50367325	50367325	G	A	SNP	AQP6	ENST00000315520	human	ensembl	74_37	+1	known	silent	c.369	p.P123	0.001	pfam_MIP,superfamily_Aquaporin-like,prints_Aquaporin_6,tigrfam_MIP	pfam_MIP,superfamily_Aquaporin-like,prints_MIP,prints_Aquaporin_6,tigrfam_MIP	-	no_errors	AQP6	HGNC	ENSG00000086159	tier1	rs150838227	-	167	0	0.00	97	42	30.22	62	0	0.00	38	8	17.39
ATRX	0	genome.wustl.edu	37	X	76875920	76875920	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	X	76875920	76875920	G	A	SNP	ATRX	ENST00000373344	human	ensembl	74_37	-1	known	nonsense	c.5215	p.R1739*	0.998	pfam_SNF2_N,superfamily_P-loop_NTPase,smart_Helicase_ATP-bd,pfscan_Helicase_ATP-bd	pfam_SNF2_N,pfam_Helicase_C,superfamily_P-loop_NTPase,superfamily_Znf_FYVE_PHD,smart_Helicase_ATP-bd,smart_Helicase_C,pfscan_Helicase_ATP-bd,pfscan_Helicase_C	-	no_errors	ATRX	HGNC	ENSG00000085224	tier1	-	-	50	0	0.00	46	32	41.03	64	0	0.00	37	30	44.78
TMEM52B	0	genome.wustl.edu	37	12	10339077	10339077	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	10339077	10339077	C	G	SNP	TMEM52B	ENST00000381923	human	ensembl	74_37	+1	known	missense	c.196	p.R66G	1.000	NULL	NULL	-	no_errors	TMEM52B	HGNC	ENSG00000165685	tier1	-	-	44	0	0.00	32	8	20.00	55	0	0.00	39	8	17.02
ERVMER61-1	0	genome.wustl.edu	37	1	187611080	187611080	+	R	SNP	T	T	G			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	187611080	187611080	T	G	SNP	ERVMER61-1	ENST00000429725	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.044	-	-	-	no_errors	ERVMER61-1	HGNC	ENSG00000230426	tier1	-	-	10	0	0.00	11	4	26.67	65	0	0.00	42	5	10.64
SLC6A17	0	genome.wustl.edu	37	1	110714771	110714771	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	110714771	110714771	C	T	SNP	SLC6A17	ENST00000331565	human	ensembl	74_37	+1	known	missense	c.376	p.R126C	1.000	pfam_Na/ntran_symport,pfscan_Na/ntran_symport	pfam_Na/ntran_symport,pfscan_Na/ntran_symport,prints_Na/ntran_symport,prints_Na/ntran_symport_orphan	-	no_errors	SLC6A17	HGNC	ENSG00000197106	tier1	-	-	93	0	0.00	78	25	24.27	32	0	0.00	34	13	27.66
PRKCG	0	genome.wustl.edu	37	19	54403679	54403679	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	54403679	54403679	C	T	SNP	PRKCG	ENST00000540413	human	ensembl	74_37	+1	known	silent	c.1380	p.Y460	0.992	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pirsf_Protein_kinase_C_a/b/g,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_C2_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_C2_dom,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_C2_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,pirsf_Protein_kinase_C_a/b/g,prints_DAG/PE-bd,prints_C2_dom,pfscan_C2_dom,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	PRKCG	HGNC	ENSG00000126583	tier1	-	-	55	0	0.00	51	13	20.31	105	0	0.00	75	16	17.20
WDR87	0	genome.wustl.edu	37	19	38380902	38380902	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	38380902	38380902	G	A	SNP	WDR87	ENST00000447313	human	ensembl	74_37	-1	known	missense	c.3409	p.R1137W	0.002	superfamily_ARM-type_fold	pfam_WD40_repeat,superfamily_WD40_repeat_dom,superfamily_ARM-type_fold,superfamily_Quinolinate_PRibosylTrfase_C,smart_WD40_repeat,pfscan_WD40_repeat,pfscan_WD40_repeat_dom	-	no_errors	WDR87	HGNC	ENSG00000171804	tier1	-	-	59	0	0.00	57	18	24.00	94	0	0.00	56	22	28.21
MGAM	0	genome.wustl.edu	37	7	141783107	141783107	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	7	141783107	141783107	C	T	SNP	MGAM	ENST00000475668	human	ensembl	74_37	+1	putative	missense	c.6275	p.T2092M	0.997	superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,smart_P_trefoil	-	no_errors	MGAM	HGNC	ENSG00000257335	tier1	-	-	36	0	0.00	39	4	9.30	47	0	0.00	36	11	23.40
ZSCAN1	0	genome.wustl.edu	37	19	58564938	58564938	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	58564938	58564938	G	A	SNP	ZSCAN1	ENST00000282326	human	ensembl	74_37	+1	known	missense	c.746	p.R249Q	0.015	NULL	pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	ZSCAN1	HGNC	ENSG00000152467	tier1	-	-	55	0	0.00	32	8	20.00	94	0	0.00	52	10	16.13
SPINK5	0	genome.wustl.edu	37	5	147499644	147499644	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	147499644	147499644	C	T	SNP	SPINK5	ENST00000359874	human	ensembl	74_37	+1	known	missense	c.2386	p.R796W	0.959	pfam_Kazal_dom,smart_Kazal_dom	pfam_Kazal_dom,smart_Kazal_dom	-	no_errors	SPINK5	HGNC	ENSG00000133710	tier1	-	-	35	0	0.00	29	5	14.71	120	0	0.00	87	19	17.92
TAS1R1	0	genome.wustl.edu	37	1	6635087	6635087	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	6635087	6635087	G	A	SNP	TAS1R1	ENST00000333172	human	ensembl	74_37	+1	known	missense	c.895	p.A299T	1.000	pfam_ANF_lig-bd_rcpt,superfamily_Peripla_BP_I	pfam_ANF_lig-bd_rcpt,pfam_GPCR_3_C,pfam_GPCR_3_9-Cys_dom,superfamily_Peripla_BP_I,pfscan_GPCR_3_C,prints_GPCR_3	-	no_errors	TAS1R1	HGNC	ENSG00000173662	tier1	-	-	32	0	0.00	27	9	25.00	32	0	0.00	37	21	36.21
ELOVL2	0	genome.wustl.edu	37	6	10995345	10995345	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	6	10995345	10995345	C	T	SNP	ELOVL2	ENST00000354666	human	ensembl	74_37	-1	known	missense	c.400	p.V134I	1.000	pfam_GNS1_SUR4	pfam_GNS1_SUR4	-	no_errors	ELOVL2	HGNC	ENSG00000197977	tier1	-	-	32	0	0.00	51	8	13.56	140	0	0.00	105	17	13.93
ABT1	0	genome.wustl.edu	37	6	26598573	26598573	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	6	26598573	26598573	G	A	SNP	ABT1	ENST00000274849	human	ensembl	74_37	+1	known	silent	c.519	p.A173	0.188	NULL	NULL	-	no_errors	ABT1	HGNC	ENSG00000146109	tier1	-	-	107	0	0.00	86	23	21.10	44	0	0.00	57	16	21.62
SPRED1	0	genome.wustl.edu	37	15	38641674	38641674	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	38641674	38641674	G	A	SNP	SPRED1	ENST00000299084	human	ensembl	74_37	+1	known	missense	c.634	p.V212I	0.997	NULL	pfam_Sprouty,pfam_WH1/EVH1,smart_WH1/EVH1,pfscan_WH1/EVH1	-	no_errors	SPRED1	HGNC	ENSG00000166068	tier1	-	-	43	0	0.00	41	11	21.15	132	0	0.00	83	21	20.19
ENSG00000257743	0	genome.wustl.edu	37	7	141871131	141871131	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	7	141871131	141871131	G	A	SNP	ENSG00000257743	ENST00000477922	human	ensembl	74_37	+1	putative	missense	c.3242	p.R1081H	0.948	superfamily_Gal_mutarotase_SF_dom	pfam_Glyco_hydro_31,pfam_P_trefoil,superfamily_Glycoside_hydrolase_SF,superfamily_Gal_mutarotase_SF_dom,superfamily_P_trefoil,smart_P_trefoil	-	no_errors	RP11-1220K2.2	Clone_based_vega_gene	ENSG00000257743	tier1	-	-	119	0	0.00	120	18	13.04	78	0	0.00	57	10	14.93
SPHK2	0	genome.wustl.edu	37	19	49129289	49129289	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	49129289	49129289	C	T	SNP	SPHK2	ENST00000443164	human	ensembl	74_37	+1	known	nonsense	c.367	p.R123*	0.058	NULL	pfam_Diacylglycerol_kinase_cat_dom,smart_Diacylglycerol_kinase_cat_dom	-	no_errors	SPHK2	HGNC	ENSG00000063176	tier1	-	-	34	0	0.00	29	8	21.62	23	0	0.00	11	4	26.67
CASQ2	0	genome.wustl.edu	37	1	116247891	116247891	+	Silent	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	116247891	116247891	G	T	SNP	CASQ2	ENST00000261448	human	ensembl	74_37	-1	known	silent	c.861	p.I287	1.000	pfam_Calsequestrin,superfamily_Thioredoxin-like_fold	pfam_Calsequestrin,superfamily_Thioredoxin-like_fold,prints_Calsequestrin	-	no_errors	CASQ2	HGNC	ENSG00000118729	tier1	rs143718767	-	56	0	0.00	45	16	26.23	129	0	0.00	94	19	16.81
MYO15A	0	genome.wustl.edu	37	17	18023186	18023186	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	18023186	18023186	C	A	SNP	MYO15A	ENST00000205890	human	ensembl	74_37	+1	known	missense	c.1072	p.L358I	0.759	NULL	pfam_Myosin_head_motor_dom,pfam_MyTH4_dom,pfam_SH3_2,pfam_FERM_central,pfam_IQ_motif_EF-hand-BS,superfamily_P-loop_NTPase,superfamily_FERM_central,superfamily_SH3_domain,smart_Myosin_head_motor_dom,smart_IQ_motif_EF-hand-BS,smart_MyTH4_dom,smart_SH3_domain,smart_Band_41_domain,pfscan_FERM_domain,pfscan_IQ_motif_EF-hand-BS,pfscan_MyTH4_dom,prints_Myosin_head_motor_dom	-	no_errors	MYO15A	HGNC	ENSG00000091536	tier1	-	-	59	0	0.00	62	10	13.89	118	0	0.00	110	13	10.57
MLLT6	0	genome.wustl.edu	37	17	36883244	36883244	+	R	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	36883244	36883244	C	T	SNP	MLLT6	ENST00000582830	human	ensembl	74_37	+1	putative	rna	NULL	NULL	0.075	-	-	-	no_errors	MLLT6	HGNC	ENSG00000108292	tier1	-	-	73	0	0.00	39	9	18.75	71	0	0.00	56	13	18.84
CCDC63	0	genome.wustl.edu	37	12	111322003	111322003	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	111322003	111322003	G	A	SNP	CCDC63	ENST00000308208	human	ensembl	74_37	+1	known	silent	c.1023	p.T341	0.777	NULL	NULL	-	no_errors	CCDC63	HGNC	ENSG00000173093	tier1	-	-	62	0	0.00	45	5	10.00	126	0	0.00	91	12	11.54
FPGT	0	genome.wustl.edu	37	1	74670983	74670983	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	74670983	74670983	G	A	SNP	FPGT	ENST00000370898	human	ensembl	74_37	+1	known	missense	c.1291	p.V431I	1.000	pfam_Fucokinase,superfamily_Trimer_LpxA-like,pirsf_Fucose-1-phosphate_GuaTrfase	pfam_Fucokinase,superfamily_Trimer_LpxA-like,pirsf_Fucose-1-phosphate_GuaTrfase	-	no_errors	FPGT	HGNC	ENSG00000254685	tier1	-	-	68	0	0.00	62	24	27.91	117	0	0.00	62	29	31.87
CAC1E	0	genome.wustl.edu	37	1	181727998	181727998	+	Silent	SNP	C	C	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	181727998	181727998	C	A	SNP	CAC1E	ENST00000367573	human	ensembl	74_37	+1	known	silent	c.4599	p.G1533	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_hand_dom,prints_VDCCAlpha1,prints_VDCC_R_a1su	-	no_errors	CAC1E	HGNC	ENSG00000198216	tier1	-	-	164	0	0.00	160	19	10.61	142	0	0.00	99	12	10.81
HTT	0	genome.wustl.edu	37	4	3215720	3215720	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	4	3215720	3215720	G	A	SNP	HTT	ENST00000355072	human	ensembl	74_37	+1	known	silent	c.6810	p.P2270	0.508	NULL	pfam_Huntingtin_middle-repeat,pfam_HEAT,superfamily_ARM-type_fold,prints_Huntingtin	-	no_errors	HTT	HGNC	ENSG00000197386	tier1	-	-	45	0	0.00	36	13	26.53	73	0	0.00	63	19	23.17
GPR151	0	genome.wustl.edu	37	5	145894881	145894881	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	145894881	145894881	C	T	SNP	GPR151	ENST00000311104	human	ensembl	74_37	-1	known	missense	c.796	p.E266K	0.894	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	-	no_errors	GPR151	HGNC	ENSG00000173250	tier1	-	-	30	0	0.00	27	11	28.95	50	0	0.00	61	12	16.44
HPN	0	genome.wustl.edu	37	19	35550828	35550828	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	35550828	35550828	C	T	SNP	HPN	ENST00000262626	human	ensembl	74_37	+1	known	missense	c.341	p.T114M	0.995	pfam_Hepsin-SRCR,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel	pfam_Peptidase_S1,pfam_Hepsin-SRCR,superfamily_Trypsin-like_Pept_dom,superfamily_Srcr_rcpt-rel,smart_Srcr_rcpt-rel,smart_Peptidase_S1,pfscan_Peptidase_S1,prints_Peptidase_S1A	-	no_errors	HPN	HGNC	ENSG00000105707	tier1	-	-	42	0	0.00	30	12	28.57	19	0	0.00	14	6	30.00
CIT	0	genome.wustl.edu	37	12	120172048	120172048	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	120172048	120172048	C	T	SNP	CIT	ENST00000261833	human	ensembl	74_37	-1	known	missense	c.3145	p.V1049I	0.981	pirsf_Citron_Rho-interacting_kinase	pfam_Citron,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_HR1_rho-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Pleckstrin_homology,smart_Citron,pirsf_Citron_Rho-interacting_kinase,pfscan_Pleckstrin_homology,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_dom	-	no_errors	CIT	HGNC	ENSG00000122966	tier1	rs200184645	GMAF=0.0005	86	0	0.00	77	11	12.50	70	0	0.00	29	5	14.71
CACNG6	0	genome.wustl.edu	37	19	54515432	54515432	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	54515432	54515432	C	T	SNP	CACNG6	ENST00000252729	human	ensembl	74_37	+1	known	missense	c.772	p.R258W	0.000	NULL	prints_VDCC_g6su,prints_VDCC_gsu,prints_Claudin	-	no_errors	CACNG6	HGNC	ENSG00000130433	tier1	-	-	44	0	0.00	52	5	8.77	22	0	0.00	17	2	10.53
SPEF2	0	genome.wustl.edu	37	5	35793303	35793303	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	35793303	35793303	G	A	SNP	SPEF2	ENST00000356031	human	ensembl	74_37	+1	known	missense	c.4597	p.V1533M	0.988	NULL	pfam_DUF1042,pfam_Adenylate_kin,pfam_HATC_dom_C,superfamily_P-loop_NTPase,superfamily_CH-domain,pfscan_CH-domain	-	no_errors	SPEF2	HGNC	ENSG00000152582	tier1	rs200747497	-	23	0	0.00	42	14	25.00	141	0	0.00	163	45	21.63
SV2B	0	genome.wustl.edu	37	15	91827281	91827281	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	91827281	91827281	G	A	SNP	SV2B	ENST00000330276	human	ensembl	74_37	+1	known	missense	c.1538	p.R513Q	0.897	superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_SV2	pfam_MFS,pfam_Sub_transporter,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_SV2	-	no_errors	SV2B	HGNC	ENSG00000185518	tier1	-	-	41	0	0.00	45	6	11.54	63	1	1.56	59	7	10.61
SIGLEC12	0	genome.wustl.edu	37	19	52002731	52002731	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	52002731	52002731	C	T	SNP	SIGLEC12	ENST00000291707	human	ensembl	74_37	-1	known	missense	c.1048	p.G350S	0.000	smart_Ig_sub,pfscan_Ig-like_dom	pfam_Ig_V-set,pfam_Ig_I-set,pfam_CD80_C2-set,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	-	no_errors	SIGLEC12	HGNC	ENSG00000254521	tier1	-	-	60	0	0.00	55	5	8.33	30	0	0.00	39	6	13.33
TP53	0	genome.wustl.edu	37	17	7577570	7577570	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	7577570	7577570	C	T	SNP	TP53	ENST00000269305	human	ensembl	74_37	-1	known	missense	c.711	p.M237I	1.000	pfam_p53_D-bd,superfamily_p53-like_TF_D-bd,prints_p53_tumour_suppressor	pfam_p53_D-bd,pfam_p53_tetrameristn,pfam_p53_transactivation_domain,superfamily_p53-like_TF_D-bd,superfamily_p53_tetrameristn,prints_p53_tumour_suppressor	-	no_errors	TP53	HGNC	ENSG00000141510	tier1	-	-	105	0	0.00	66	57	46.34	82	1	1.19	50	45	46.88
KNDC1	0	genome.wustl.edu	37	10	134981792	134981792	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	134981792	134981792	C	T	SNP	KNDC1	ENST00000368572	human	ensembl	74_37	+1	known	silent	c.336	p.F112	0.987	superfamily_Kinase-like_dom,smart_KIND	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,superfamily_Kinase-like_dom,smart_KIND,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	KNDC1	HGNC	ENSG00000171798	tier1	-	-	103	0	0.00	55	25	31.25	116	0	0.00	80	22	21.57
CXorf30	0	genome.wustl.edu	37	X	36329023	36329023	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	X	36329023	36329023	C	T	SNP	CXorf30	ENST00000378657	human	ensembl	74_37	+1	known	missense	c.601	p.R201C	0.000	NULL	NULL	-	no_errors	CXorf30	HGNC	ENSG00000205081	tier1	-	-	24	0	0.00	31	11	26.19	80	0	0.00	52	16	23.53
MIR202	0	genome.wustl.edu	37	10	135061123	135061123	+	R	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	135061123	135061123	C	T	SNP	MIR202	ENST00000300167	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	MIR202	HGNC	ENSG00000166917	tier1	-	-	100	0	0.00	67	22	23.66	73	0	0.00	57	21	26.92
OR8H1	0	genome.wustl.edu	37	11	56057792	56057792	+	Silent	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	56057792	56057792	G	T	SNP	OR8H1	ENST00000313022	human	ensembl	74_37	-1	known	silent	c.747	p.I249	0.089	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8H1	HGNC	ENSG00000181693	tier1	-	-	42	0	0.00	48	13	21.31	55	0	0.00	47	15	24.19
KRT6C	0	genome.wustl.edu	37	12	52867478	52867478	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	52867478	52867478	C	T	SNP	KRT6C	ENST00000252250	human	ensembl	74_37	-1	known	missense	c.44	p.R15H	0.000	NULL	pfam_IF,superfamily_Prefoldin,prints_Keratin_II	-	no_errors	KRT6C	HGNC	ENSG00000170465	tier1	rs142765056	-	100	0	0.00	72	31	30.10	34	0	0.00	22	7	24.14
KDM5C	0	genome.wustl.edu	37	X	53246347	53246347	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	X	53246347	53246347	C	T	SNP	KDM5C	ENST00000375401	human	ensembl	74_37	-1	known	missense	c.635	p.R212Q	1.000	NULL	pfam_Lys_sp_deMease_like_dom,pfam_JmjC_dom,pfam_ARID/BRIGHT_D-bd,pfam_Znf_C5HC2,pfam_Znf_PHD-finger,pfam_TF_JmjN,superfamily_ARID/BRIGHT_D-bd,superfamily_Znf_FYVE_PHD,smart_TF_JmjN,smart_ARID/BRIGHT_D-bd,smart_Znf_PHD,smart_JmjC_dom,pfscan_TF_JmjN,pfscan_JmjC_dom,pfscan_Znf_PHD-finger,pfscan_ARID/BRIGHT_D-bd	-	no_errors	KDM5C	HGNC	ENSG00000126012	tier1	-	-	19	0	0.00	10	14	58.33	39	0	0.00	24	14	36.84
GPT2	0	genome.wustl.edu	37	16	46943614	46943614	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	16	46943614	46943614	G	A	SNP	GPT2	ENST00000340124	human	ensembl	74_37	+1	known	missense	c.595	p.V199I	1.000	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase	pfam_Aminotransferase_I/II,superfamily_PyrdxlP-dep_Trfase	-	no_errors	GPT2	HGNC	ENSG00000166123	tier1	-	-	75	0	0.00	101	25	19.84	119	0	0.00	124	42	25.30
SPTBN4	0	genome.wustl.edu	37	19	41025405	41025405	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	41025405	41025405	G	A	SNP	SPTBN4	ENST00000352632	human	ensembl	74_37	+1	known	missense	c.3001	p.A1001T	0.990	pirsf_Spectrin_bsu,smart_Spectrin/alpha-actinin	pirsf_Spectrin_bsu,pfam_Spectrin_repeat,pfam_CH-domain,pfam_Pleckstrin_homology,pfam_CAMSAP_CH,superfamily_CH-domain,smart_CH-domain,smart_Spectrin/alpha-actinin,smart_Pleckstrin_homology,prints_PH_dom-spectrin-type,pfscan_CH-domain,pfscan_Pleckstrin_homology	-	no_errors	SPTBN4	HGNC	ENSG00000160460	tier1	-	-	86	0	0.00	50	9	15.25	18	0	0.00	12	4	25.00
OR7G2	0	genome.wustl.edu	37	19	9213641	9213641	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	9213641	9213641	C	T	SNP	OR7G2	ENST00000305456	human	ensembl	74_37	-1	known	silent	c.342	p.T114	0.000	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt	pfam_GPCR_Rhodpsn,pfam_7TM_GPCR_olfarory/Srsx,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR7G2	HGNC	ENSG00000170923	tier1	-	-	80	0	0.00	76	23	23.23	85	0	0.00	73	31	29.81
WDFY4	0	genome.wustl.edu	37	10	49944117	49944117	+	Splice_Site	SNP	T	T	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	49944117	49944117	T	A	SNP	WDFY4	ENST00000325239	human	ensembl	74_37	+1	known	splice_site	c.1878+2	e10+2	0.999	-	-	-	no_errors	WDFY4	HGNC	ENSG00000128815	tier1	-	-	44	0	0.00	38	11	22.45	55	0	0.00	62	7	10.14
SCAF1	0	genome.wustl.edu	37	19	50150007	50150007	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	50150007	50150007	G	A	SNP	SCAF1	ENST00000360565	human	ensembl	74_37	+1	known	missense	c.398	p.R133Q	0.909	NULL	NULL	-	no_errors	SCAF1	HGNC	ENSG00000126461	tier1	-	-	40	0	0.00	44	7	13.73	64	0	0.00	37	8	17.78
PEG3	0	genome.wustl.edu	37	19	57329980	57329980	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	57329980	57329980	G	T	SNP	PEG3	ENST00000326441	human	ensembl	74_37	-1	known	missense	c.760	p.L254M	1.000	NULL	pfam_Znf_C2H2,pfam_Tscrpt_reg_SCAN,superfamily_Retrov_capsid_C,smart_Tscrpt_reg_SCAN,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Tscrpt_reg_SCAN	-	no_errors	PEG3	HGNC	ENSG00000198300	tier1	-	-	109	0	0.00	96	11	10.28	89	0	0.00	85	10	10.53
KRT35	0	genome.wustl.edu	37	17	39635725	39635725	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	39635725	39635725	C	T	SNP	KRT35	ENST00000393989	human	ensembl	74_37	-1	known	silent	c.585	p.L195	1.000	pfam_IF	pfam_IF,superfamily_Prefoldin,prints_Keratin_I	-	no_errors	KRT35	HGNC	ENSG00000197079	tier1	-	-	74	0	0.00	64	10	13.51	31	0	0.00	18	2	10.00
RBBP8NL	0	genome.wustl.edu	37	20	60987919	60987919	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	20	60987919	60987919	G	A	SNP	RBBP8NL	ENST00000252998	human	ensembl	74_37	-1	known	silent	c.1713	p.D571	0.000	NULL	pfam_CtIP_N	-	no_errors	RBBP8NL	HGNC	ENSG00000130701	tier1	-	-	134	0	0.00	81	34	29.57	42	0	0.00	24	13	34.21
NOTCH4	0	genome.wustl.edu	37	6	32188188	32188188	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	6	32188188	32188188	G	A	SNP	NOTCH4	ENST00000375023	human	ensembl	74_37	-1	known	missense	c.1153	p.R385C	1.000	pirsf_Notch,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,pfscan_EG-like_dom	pirsf_Notch,pfam_EG-like_dom,pfam_Ankyrin_rpt,pfam_EGF-like_Ca-bd_dom,pfam_Notch_dom,pfam_Notch_NODP_dom,superfamily_Ankyrin_rpt-contain_dom,superfamily_Notch_dom,smart_EG-like_dom,smart_EGF-like_Ca-bd_dom,smart_Notch_dom,smart_Ankyrin_rpt,prints_Notch_4,prints_Notch_dom,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,pfscan_EG-like_dom,pfscan_Notch_dom	-	no_errors	NOTCH4	HGNC	ENSG00000204301	tier1	-	-	99	0	0.00	80	22	21.57	100	0	0.00	91	19	17.27
OR8H2	0	genome.wustl.edu	37	11	55872648	55872648	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	55872648	55872648	G	A	SNP	OR8H2	ENST00000313503	human	ensembl	74_37	+1	known	missense	c.130	p.V44M	0.003	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_GPCR_Rhodpsn	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_Olfact_rcpt,prints_GPCR_Rhodpsn	-	no_errors	OR8H2	HGNC	ENSG00000181767	tier1	-	-	93	0	0.00	89	17	15.89	50	0	0.00	43	23	34.85
ENSG00000237452	0	genome.wustl.edu	37	19	46257882	46257882	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	46257882	46257882	G	A	SNP	ENSG00000237452	ENST00000457052	human	ensembl	74_37	+1	putative	silent	c.702	p.P234	0.002	NULL	pfam_HMG_box_dom,pfam_bHLH_dom,superfamily_HMG_box_dom,superfamily_bHLH_dom,smart_HMG_box_dom,pfscan_bHLH_dom,pfscan_HMG_box_dom	-	no_errors	AC074212.3	Clone_based_vega_gene	ENSG00000237452	tier1	-	-	45	0	0.00	45	8	15.09	45	0	0.00	46	12	20.69
ITGB2	0	genome.wustl.edu	37	21	46323418	46323418	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	21	46323418	46323418	G	A	SNP	ITGB2	ENST00000302347	human	ensembl	74_37	-1	known	missense	c.361	p.R121W	1.000	pirsf_Integrin_bsu,pfam_Integrin_bsu_N,smart_Integrin_bsu_N	pirsf_Integrin_bsu,pfam_Integrin_bsu_N,pfam_Integrin_bsu_tail,pfam_Integrin_bsu_cyt_dom,pfam_EGF_extracell,superfamily_Integrin_bsu_tail,superfamily_Plexin-like_fold,smart_Plexin-like_fold,smart_Integrin_bsu_N,prints_Integrin_bsu	-	no_errors	ITGB2	HGNC	ENSG00000160255	tier1	-	-	66	0	0.00	88	18	16.98	79	0	0.00	57	9	13.64
TBC1D12	0	genome.wustl.edu	37	10	96282101	96282101	+	Missense_Mutation	SNP	A	A	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	A	A	A	T	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	96282101	96282101	A	T	SNP	TBC1D12	ENST00000225235	human	ensembl	74_37	+1	known	missense	c.1891	p.M631L	1.000	pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	pfam_Rab-GTPase-TBC_dom,superfamily_Rab-GTPase-TBC_dom,smart_Rab-GTPase-TBC_dom,pfscan_Rab-GTPase-TBC_dom	-	no_errors	TBC1D12	HGNC	ENSG00000108239	tier1	-	-	29	0	0.00	33	4	10.81	100	0	0.00	50	10	16.67
TUB	0	genome.wustl.edu	37	11	8123044	8123044	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	8123044	8123044	G	A	SNP	TUB	ENST00000305253	human	ensembl	74_37	+1	known	missense	c.1564	p.V522M	1.000	pfam_Tubby_C,superfamily_Tubby_C-like,prints_Tubby_C	pfam_Tubby_C,superfamily_Tubby_C-like,prints_Tubby_N,prints_Tubby_C	-	no_errors	TUB	HGNC	ENSG00000166402	tier1	-	-	129	0	0.00	108	13	10.74	96	0	0.00	79	9	10.23
ZNF85	0	genome.wustl.edu	37	19	21132245	21132245	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	21132245	21132245	A	G	SNP	ZNF85	ENST00000328178	human	ensembl	74_37	+1	known	missense	c.925	p.T309A	1.000	pfscan_Znf_C2H2	pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box	-	no_errors	ZNF85	HGNC	ENSG00000105750	tier1	-	-	18	0	0.00	17	14	45.16	20	0	0.00	17	12	41.38
GBGT1	0	genome.wustl.edu	37	9	136030486	136030486	+	R	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	9	136030486	136030486	G	A	SNP	GBGT1	ENST00000470431	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	GBGT1	HGNC	ENSG00000148288	tier1	-	-	74	0	0.00	56	14	20.00	69	0	0.00	66	18	21.18
PCDH1	0	genome.wustl.edu	37	5	141248661	141248661	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	141248661	141248661	G	T	SNP	PCDH1	ENST00000287008	human	ensembl	74_37	-1	known	missense	c.376	p.Q126K	1.000	pfam_Cadherin_N,superfamily_Cadherin-like,pfscan_Cadherin	pfam_Cadherin,pfam_Protocadherin,pfam_Cadherin_N,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin,prints_Cadherin	-	no_errors	PCDH1	HGNC	ENSG00000156453	tier1	-	-	39	0	0.00	23	8	25.81	71	0	0.00	59	9	13.24
ARHGAP21	0	genome.wustl.edu	37	10	24874948	24874948	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	24874948	24874948	G	T	SNP	ARHGAP21	ENST00000396432	human	ensembl	74_37	-1	known	missense	c.4270	p.P1424T	0.795	NULL	pfam_RhoGAP_dom,pfam_Pleckstrin_homology,pfam_PDZ,superfamily_Rho_GTPase_activation_prot,superfamily_PDZ,smart_PDZ,smart_Pleckstrin_homology,smart_RhoGAP_dom,pfscan_PDZ,pfscan_Pleckstrin_homology,pfscan_RhoGAP_dom	-	no_errors	ARHGAP21	HGNC	ENSG00000107863	tier1	-	-	82	0	0.00	74	8	9.76	40	0	0.00	32	6	15.79
MICAL2	0	genome.wustl.edu	37	11	12231105	12231105	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	12231105	12231105	C	T	SNP	MICAL2	ENST00000256194	human	ensembl	74_37	+1	known	silent	c.651	p.D217	0.995	prints_Rng_hydrolase-like	pfam_CH-domain,pfam_CAMSAP_CH,pfam_Znf_LIM,pfam_mOase_FAD-bd,pfam_FAD_bind_dom,superfamily_CH-domain,smart_CH-domain,smart_Znf_LIM,pfscan_CH-domain,pfscan_Znf_LIM,prints_Rng_hydrolase-like	-	no_errors	MICAL2	HGNC	ENSG00000133816	tier1	-	-	48	0	0.00	44	4	8.33	94	0	0.00	84	10	10.64
TECTA	0	genome.wustl.edu	37	11	120989346	120989346	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	120989346	120989346	C	T	SNP	TECTA	ENST00000264037	human	ensembl	74_37	+1	known	silent	c.1122	p.A374	0.012	pfam_VWF_type-D,smart_VWF_type-D	pfam_VWF_type-D,pfam_Unchr_dom_Cys-rich,pfam_ZP_dom,pfam_Nidogen_extracell_dom,pfam_TIL_dom,superfamily_TIL_dom,smart_Nidogen_extracell_dom,smart_VWC_out,smart_VWF_type-D,smart_Unchr_dom_Cys-rich,smart_EG-like_dom,smart_ZP_dom,pfscan_ZP_dom	-	no_errors	TECTA	HGNC	ENSG00000109927	tier1	-	-	58	0	0.00	40	6	13.04	106	0	0.00	63	9	12.50
LOC100996415	0	genome.wustl.edu	37	22	20341941	20341941	+	R	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	22	20341941	20341941	C	T	SNP	LOC100996415	ENST00000454636	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	XXbac-B33L19.3	Clone_based_vega_gene	ENSG00000188424	tier1	-	-	127	0	0.00	110	27	19.71	19	0	0.00	10	2	16.67
FAM135B	0	genome.wustl.edu	37	8	139268947	139268947	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	8	139268947	139268947	G	A	SNP	FAM135B	ENST00000395297	human	ensembl	74_37	-1	known	missense	c.353	p.T118M	1.000	pfam_DUF3657	pfam_DUF676_lipase-like,pfam_DUF3657,pfam_PGAP1-like	-	no_errors	FAM135B	HGNC	ENSG00000147724	tier1	-	-	32	0	0.00	18	5	21.74	120	0	0.00	56	23	29.11
HDAC6	0	genome.wustl.edu	37	X	48678568	48678568	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	X	48678568	48678568	C	T	SNP	HDAC6	ENST00000444343	human	ensembl	74_37	+1	known	missense	c.2285	p.P762L	0.999	pfam_His_deacetylse_dom	pfam_His_deacetylse_dom,pfam_Znf_UBP,smart_Znf_UBP,pfscan_Znf_UBP,prints_His_deacetylse	-	no_errors	HDAC6	HGNC	ENSG00000094631	tier1	-	-	55	0	0.00	46	7	13.21	18	0	0.00	13	5	27.78
EPYC	0	genome.wustl.edu	37	12	91363850	91363850	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	91363850	91363850	G	A	SNP	EPYC	ENST00000261172	human	ensembl	74_37	-1	known	missense	c.769	p.P257S	1.000	smart_Leu-rich_rpt_typical-subtyp	pfam_LRR-contain_N,smart_LRR-contain_N,smart_Leu-rich_rpt_typical-subtyp	-	no_errors	EPYC	HGNC	ENSG00000083782	tier1	-	-	91	0	0.00	102	18	15.00	101	0	0.00	103	26	20.00
SLC16A5	0	genome.wustl.edu	37	17	73096768	73096768	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	73096768	73096768	C	T	SNP	SLC16A5	ENST00000329783	human	ensembl	74_37	+1	known	missense	c.1010	p.A337V	0.959	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt	pfam_MFS,superfamily_MFS_dom_general_subst_transpt,pfscan_MFS_dom,tigrfam_Monocarb_transpt	-	no_errors	SLC16A5	HGNC	ENSG00000170190	tier1	-	-	50	0	0.00	39	13	25.00	59	0	0.00	53	18	25.35
RSAD1	0	genome.wustl.edu	37	17	48562112	48562112	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	17	48562112	48562112	C	T	SNP	RSAD1	ENST00000258955	human	ensembl	74_37	+1	known	missense	c.1219	p.R407W	1.000	pfam_HemN_C_dom	pfam_HemN_C_dom,pfam_rSAM,smart_Elp3/MiaB/NifB,tigrfam_Coprogen_oxidase_HemN-rel	-	no_errors	RSAD1	HGNC	ENSG00000136444	tier1	-	-	89	0	0.00	95	11	10.38	99	0	0.00	70	12	14.63
JAKMIP1	0	genome.wustl.edu	37	4	6082016	6082016	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	4	6082016	6082016	C	T	SNP	JAKMIP1	ENST00000409021	human	ensembl	74_37	-1	known	silent	c.1125	p.A375	0.048	NULL	NULL	-	no_errors	JAKMIP1	HGNC	ENSG00000152969	tier1	rs150623866	-	59	0	0.00	46	15	24.59	43	0	0.00	26	4	13.33
LPCAT4	0	genome.wustl.edu	37	15	34651485	34651489	+	Frame_Shift_Del	DEL	GAGAA	GAGAA	-			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	GAGAA	GAGAA	GAGAA	-	GAGAA	GAGAA	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	34651485	34651489	GAGAA	-	DEL	LPCAT4	ENST00000314891	human	ensembl	74_37	-1	known	frame_shift_del	c.1418_1414	p.F472fs	1.000:1.000:1.000:1.000:1.000	NULL	pfam_Plipid/glycerol_acylTrfase,smart_Plipid/glycerol_acylTrfase	-	no_errors	LPCAT4	HGNC	ENSG00000176454	tier1			104	0	0.00	91	15	14.15	104	0	0.00	91	15	14.15
CAC1F	0	genome.wustl.edu	37	X	49074970	49074970	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	X	49074970	49074970	G	A	SNP	CAC1F	ENST00000376265	human	ensembl	74_37	-1	known	nonsense	c.2905	p.R969*	0.989	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,prints_VDCCAlpha1,prints_VDCC_L_a1su	-	no_errors	CAC1F	HGNC	ENSG00000102001	tier1	rs122456134	-	43	0	0.00	21	23	52.27	15	0	0.00	3	3	50.00
LINC00917	0	genome.wustl.edu	37	16	86371004	86371004	+	R	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	16	86371004	86371004	G	A	SNP	LINC00917	ENST00000304488	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	LINC00917	HGNC	ENSG00000168367	tier1	-	-	48	0	0.00	61	15	19.74	20	0	0.00	7	5	41.67
SCN3A	0	genome.wustl.edu	37	2	166011012	166011012	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	2	166011012	166011012	C	T	SNP	SCN3A	ENST00000283254	human	ensembl	74_37	-1	known	missense	c.1330	p.E444K	1.000	NULL	pfam_Ion_trans_dom,pfam_DUF3451,pfam_Na_trans_assoc,pfam_PKD1_2_channel,pfscan_IQ_motif_EF-hand-BS,prints_Na_channel_asu,prints_PKD_2	-	no_errors	SCN3A	HGNC	ENSG00000153253	tier1	-	-	77	0	0.00	51	29	36.25	13	0	0.00	8	4	33.33
LINC00905	0	genome.wustl.edu	37	19	16145008	16145008	+	R	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	16145008	16145008	G	A	SNP	LINC00905	ENST00000588838	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.954	-	-	-	no_errors	LINC00905	HGNC	ENSG00000167459	tier1	-	-	73	0	0.00	60	6	9.09	77	0	0.00	101	7	6.48
CEP350	0	genome.wustl.edu	37	1	179983057	179983057	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	179983057	179983057	G	A	SNP	CEP350	ENST00000367607	human	ensembl	74_37	+1	known	missense	c.1469	p.R490H	1.000	NULL	pfam_CAP-Gly_domain,superfamily_CAP-Gly_domain,pfscan_CAP-Gly_domain	-	no_errors	CEP350	HGNC	ENSG00000135837	tier1	-	-	44	0	0.00	44	4	8.33	106	0	0.00	99	7	6.60
RP1	0	genome.wustl.edu	37	8	55534123	55534123	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	8	55534123	55534123	C	T	SNP	RP1	ENST00000220676	human	ensembl	74_37	+1	known	silent	c.597	p.Y199	0.762	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	pfam_Doublecortin_dom,smart_Doublecortin_dom,pfscan_Doublecortin_dom	-	no_errors	RP1	HGNC	ENSG00000104237	tier1	-	-	44	0	0.00	38	6	13.64	71	0	0.00	39	4	9.30
SEMA6D	0	genome.wustl.edu	37	15	48057167	48057167	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	48057167	48057167	G	T	SNP	SEMA6D	ENST00000316364	human	ensembl	74_37	+1	known	missense	c.1341	p.M447I	0.849	pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pfam_Semap_dom,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,pfscan_Semap_dom	-	no_errors	SEMA6D	HGNC	ENSG00000137872	tier1	-	-	57	0	0.00	49	10	16.95	118	0	0.00	72	7	8.86
NSUN6	0	genome.wustl.edu	37	10	18874941	18874941	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	10	18874941	18874941	T	A	SNP	NSUN6	ENST00000377304	human	ensembl	74_37	-1	known	missense	c.859	p.I287F	1.000	pfam_Fmu/NOL1/Nop2p,pfam_rR_MeTrfase_FtsJ_dom	pfam_Fmu/NOL1/Nop2p,pfam_rR_MeTrfase_FtsJ_dom,pfam_PUA,superfamily_PUA-like_domain,pfscan_PUA,prints_RCMT	-	no_errors	NSUN6	HGNC	ENSG00000241058	tier1	-	-	42	0	0.00	45	5	10.00	149	0	0.00	101	9	8.11
C1orf61	0	genome.wustl.edu	37	1	156377337	156377337	+	R	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	156377337	156377337	C	T	SNP	C1orf61	ENST00000488498	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.946	-	-	-	no_errors	C1orf61	HGNC	ENSG00000125462	tier1	-	-	43	0	0.00	44	10	18.52	98	0	0.00	54	5	8.47
RASAL2	0	genome.wustl.edu	37	1	178427542	178427542	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	178427542	178427542	G	A	SNP	RASAL2	ENST00000367649	human	ensembl	74_37	+1	known	missense	c.3115	p.G1039R	0.994	pfam_DUF3498	pfam_DUF3498,pfam_RasGAP,pfam_Pleckstrin_homology,pfam_C2_dom,superfamily_Rho_GTPase_activation_prot,superfamily_C2_dom,superfamily_PP1_inhibitor,smart_Pleckstrin_homology,smart_C2_dom,smart_RasGAP,pfscan_Pleckstrin_homology,pfscan_RasGAP	-	no_errors	RASAL2	HGNC	ENSG00000075391	tier1	-	-	59	0	0.00	50	9	15.25	101	0	0.00	63	4	5.97
LRRK1	0	genome.wustl.edu	37	15	101605774	101605774	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	101605774	101605774	C	T	SNP	LRRK1	ENST00000388948	human	ensembl	74_37	+1	known	missense	c.5132	p.P1711L	1.000	superfamily_WD40_repeat_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Leu-rich_rpt,pfam_MIRO-like,pfam_Small_GTPase_ARF/SAR,pfam_Small_GTPase,superfamily_Kinase-like_dom,superfamily_P-loop_NTPase,superfamily_Ankyrin_rpt-contain_dom,superfamily_WD40_repeat_dom,smart_Ankyrin_rpt,smart_Leu-rich_rpt_typical-subtyp,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Ankyrin_rpt-contain_dom,pfscan_Prot_kinase_dom	-	no_errors	LRRK1	HGNC	ENSG00000154237	tier1	-	-	29	0	0.00	22	4	15.38	76	0	0.00	77	4	4.94
QTRTD1	0	genome.wustl.edu	37	3	113804664	113804664	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	3	113804664	113804664	C	T	SNP	QTRTD1	ENST00000281273	human	ensembl	74_37	+1	known	silent	c.1161	p.Y387	0.995	pfam_tR_ribo_trans-like,superfamily_tR_ribo_trans-like,tigrfam_tR_ribo_trans-like	pfam_tR_ribo_trans-like,superfamily_tR_ribo_trans-like,tigrfam_tR_ribo_trans-like	-	no_errors	QTRTD1	HGNC	ENSG00000151576	tier1	-	-	124	0	0.00	115	13	10.16	107	0	0.00	84	9	9.68
ASPG	0	genome.wustl.edu	37	14	104565230	104565230	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	14	104565230	104565230	G	A	SNP	ASPG	ENST00000455920	human	ensembl	74_37	+1	known	missense	c.554	p.R185Q	0.994	pfam_Asparaginase/glutaminase,superfamily_Asparaginase/glutaminase,smart_Asparaginase/glutaminase,tigrfam_AsnASEI	pfam_Asparaginase/glutaminase,pfam_Ankyrin_rpt,superfamily_Asparaginase/glutaminase,superfamily_Ankyrin_rpt-contain_dom,smart_Asparaginase/glutaminase,smart_Ankyrin_rpt,prints_Asparaginase/glutaminase,prints_Ankyrin_rpt,pfscan_Ankyrin_rpt,pfscan_Ankyrin_rpt-contain_dom,tigrfam_AsnASEI	-	no_errors	ASPG	HGNC	ENSG00000166183	tier1	-	-	105	0	0.00	115	11	8.73	76	1	1.30	62	5	7.46
ERAP2	0	genome.wustl.edu	37	5	96215697	96215697	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	96215697	96215697	A	G	SNP	ERAP2	ENST00000437043	human	ensembl	74_37	+1	known	missense	c.308	p.N103S	0.102	pfam_Peptidase_M1_N	pfam_Peptidase_M1_N,prints_Peptidase_M1_N	-	no_errors	ERAP2	HGNC	ENSG00000164308	tier1	-	-	52	0	0.00	52	5	8.77	63	0	0.00	66	5	7.04
ENSG00000254553	0	genome.wustl.edu	37	1	32950780	32950780	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	32950780	32950780	C	T	SNP	ENSG00000254553	ENST00000480336	human	ensembl	74_37	+1	known	missense	c.1249	p.R417C	1.000	NULL	pfam_BTB_POZ,pfam_Znf_C2H2,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_Znf_C2H2-like,pfscan_BTB/POZ-like,pfscan_Znf_C2H2	-	no_errors	RP1-27O5.3	Clone_based_vega_gene	ENSG00000254553	tier1	-	-	50	0	0.00	63	6	8.70	42	0	0.00	48	5	9.43
TAF6L	0	genome.wustl.edu	37	11	62553797	62553797	+	Missense_Mutation	SNP	T	T	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	11	62553797	62553797	T	A	SNP	TAF6L	ENST00000294168	human	ensembl	74_37	+1	known	missense	c.1026	p.D342E	0.957	NULL	pfam_TAF_TATA-bd,pfam_DUF1546,superfamily_Histone-fold,smart_TAF_TATA-bd	-	no_errors	TAF6L	HGNC	ENSG00000162227	tier1	-	-	42	0	0.00	49	6	10.91	120	0	0.00	102	5	4.67
TMEFF1	0	genome.wustl.edu	37	9	103261070	103261070	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	9	103261070	103261070	G	A	SNP	TMEFF1	ENST00000374879	human	ensembl	74_37	+1	known	missense	c.220	p.V74I	0.945	NULL	pfam_Kazal_dom,smart_Kazal_dom,pfscan_EG-like_dom	-	no_errors	TMEFF1	HGNC	ENSG00000241697	tier1	-	-	37	0	0.00	65	6	8.45	93	0	0.00	85	6	6.59
SLC32A1	0	genome.wustl.edu	37	20	37356570	37356570	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	20	37356570	37356570	C	T	SNP	SLC32A1	ENST00000217420	human	ensembl	74_37	+1	known	missense	c.866	p.A289V	1.000	pfam_AA_transpt_TM	pfam_AA_transpt_TM	-	no_errors	SLC32A1	HGNC	ENSG00000101438	tier1	-	-	56	0	0.00	66	6	8.33	107	0	0.00	86	7	7.53
PIWIL2	0	genome.wustl.edu	37	8	22172555	22172555	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	8	22172555	22172555	G	A	SNP	PIWIL2	ENST00000356766	human	ensembl	74_37	+1	known	missense	c.2105	p.R702Q	1.000	pfam_Piwi,superfamily_RNaseH-like_dom,smart_Piwi,pfscan_Piwi	pfam_Piwi,pfam_PAZ_dom,superfamily_RNaseH-like_dom,superfamily_PAZ_dom,smart_PAZ_dom,smart_Piwi,pfscan_PAZ_dom,pfscan_Piwi	-	no_errors	PIWIL2	HGNC	ENSG00000197181	tier1	-	-	86	0	0.00	79	8	9.20	107	0	0.00	125	11	8.09
GSK3A	0	genome.wustl.edu	37	19	42744317	42744317	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	42744317	42744317	G	A	SNP	GSK3A	ENST00000398249	human	ensembl	74_37	-1	novel	silent	c.15	p.I5	0.000	NULL	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	GSK3A	HGNC	ENSG00000105723	tier1	-	-	90	0	0.00	82	9	9.89	86	0	0.00	71	6	7.79
LOXHD1	0	genome.wustl.edu	37	18	44102227	44102227	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	18	44102227	44102227	G	A	SNP	LOXHD1	ENST00000536736	human	ensembl	74_37	-1	known	missense	c.4922	p.A1641V	0.727	superfamily_Lipase_LipOase	pfam_PLAT/LH2_dom,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,pfscan_PLAT/LH2_dom	-	no_errors	LOXHD1	HGNC	ENSG00000167210	tier1	-	-	36	0	0.00	33	6	15.38	91	0	0.00	85	4	4.49
TLN2	0	genome.wustl.edu	37	15	63097816	63097816	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	63097816	63097816	C	T	SNP	TLN2	ENST00000306829	human	ensembl	74_37	+1	known	silent	c.6495	p.D2165	0.000	NULL	pfam_Talin_cent,pfam_ILWEQ_dom,pfam_Vinculin-bd_dom,pfam_FERM_N,pfam_FERM_central,pfam_Insln_rcpt_S1,superfamily_Talin_cent,superfamily_Vinculin/catenin,superfamily_FERM_central,smart_Band_41_domain,smart_ILWEQ_dom,pfscan_FERM_domain,pfscan_ILWEQ_dom	-	no_errors	TLN2	HGNC	ENSG00000171914	tier1	-	-	46	0	0.00	41	6	12.77	95	0	0.00	80	8	9.09
ARHGAP18	0	genome.wustl.edu	37	6	129905211	129905211	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	6	129905211	129905211	G	A	SNP	ARHGAP18	ENST00000368149	human	ensembl	74_37	-1	known	missense	c.1760	p.S587L	1.000	NULL	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom	-	no_errors	ARHGAP18	HGNC	ENSG00000146376	tier1	rs137871841	-	50	0	0.00	48	5	9.43	79	0	0.00	76	8	9.52
SYT4	0	genome.wustl.edu	37	18	40850433	40850433	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	18	40850433	40850433	C	T	SNP	SYT4	ENST00000255224	human	ensembl	74_37	-1	known	missense	c.1151	p.R384Q	1.000	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom,prints_Synaptotagmin	-	no_errors	SYT4	HGNC	ENSG00000132872	tier1	rs149020215	-	43	0	0.00	45	4	8.16	114	0	0.00	97	5	4.85
CD209	0	genome.wustl.edu	37	19	7808072	7808072	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	7808072	7808072	G	A	SNP	CD209	ENST00000601256	human	ensembl	74_37	-1	known	missense	c.883	p.R295C	0.012	NULL	superfamily_C-type_lectin_fold	-	no_errors	CD209	HGNC	ENSG00000090659	tier1	-	-	78	0	0.00	71	17	19.32	119	2	1.65	110	8	6.78
CSPG4	0	genome.wustl.edu	37	15	75982848	75982848	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	75982848	75982848	G	A	SNP	CSPG4	ENST00000308508	human	ensembl	74_37	-1	known	silent	c.558	p.P186	0.000	superfamily_ConA-like_lec_gl_sf,pfscan_Laminin_G	pfam_Laminin_G,superfamily_ConA-like_lec_gl_sf,smart_Laminin_G,pfscan_Laminin_G	-	no_errors	CSPG4	HGNC	ENSG00000173546	tier1	-	-	110	0	0.00	87	18	17.14	7	0	0.00	4	1	20.00
ENSG00000271959	0	genome.wustl.edu	37	8	142445541	142445542	+	R	INS	-	-	CCCGCGGCCCTGGCCCG			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	8	142445541	142445542	-	CCCGCGGCCCTGGCCCG	INS	ENSG00000271959	ENST00000606664	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	CTD-3064M3.7	Clone_based_vega_gene	ENSG00000271959	tier1			10	0	0.00	3	0	0.00	10	0	0.00	3	0	0.00
SOHLH1	0	genome.wustl.edu	37	9	138586907	138586907	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	9	138586907	138586907	C	T	SNP	SOHLH1	ENST00000425225	human	ensembl	74_37	-1	known	silent	c.864	p.A288	0.000	NULL	pfam_bHLH_dom,superfamily_bHLH_dom,smart_bHLH_dom,pfscan_bHLH_dom	-	no_errors	SOHLH1	HGNC	ENSG00000165643	tier1	-	-	17	0	0.00	17	4	18.18	6	0	0.00	5	0	0.00
GOLGA8S	0	genome.wustl.edu	37	15	23605389	23605389	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	15	23605389	23605389	G	A	SNP	GOLGA8S	ENST00000562295	human	ensembl	74_37	+1	novel	missense	c.602	p.R201H	0.094	NULL	NULL	-	no_errors	GOLGA8S	HGNC	ENSG00000261739	tier1	-	-	260	0	0.00	241	35	12.64	0	0	0.00	1	0	0.00
OBSCN	0	genome.wustl.edu	37	1	228451900	228451900	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	228451900	228451900	G	A	SNP	OBSCN	ENST00000422127	human	ensembl	74_37	+1	known	missense	c.4669	p.E1557K	1.000	pfam_Ig_I-set,pfam_Immunoglobulin,smart_Ig_sub,smart_Ig_sub2,pfscan_Ig-like_dom	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Fibronectin_type3,pfam_DH-domain,pfam_IQ_motif_EF-hand-BS,superfamily_Kinase-like_dom,superfamily_DH-domain,superfamily_Fibronectin_type3,superfamily_SH3_domain,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_IQ_motif_EF-hand-BS,smart_DH-domain,smart_Pleckstrin_homology,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_IQ_motif_EF-hand-BS,pfscan_Pleckstrin_homology,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,pfscan_DH-domain	-	no_errors	OBSCN	HGNC	ENSG00000154358	tier1	-	-	161	0	0.00	96	35	26.72	2	0	0.00	0	0	0.00
ATAD3C	0	genome.wustl.edu	37	1	1386075	1386075	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	1	1386075	1386075	C	T	SNP	ATAD3C	ENST00000378785	human	ensembl	74_37	+1	known	silent	c.12	p.D4	0.972	NULL	pfam_DUF3523,pfam_ATPase_AAA_core,pfam_D_helicase_Holl-junc_RuvB_N,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	ATAD3C	HGNC	ENSG00000215915	tier1	-	-	71	0	0.00	48	23	32.39	4	0	0.00	6	4	40.00
TAPBPL	0	genome.wustl.edu	37	12	6567949	6567949	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	12	6567949	6567949	C	G	SNP	TAPBPL	ENST00000266556	human	ensembl	74_37	+1	known	missense	c.1043	p.S348C	0.194	pfam_Ig_C1-set,smart_Ig_C1-set,pfscan_Ig-like_dom	pfam_Ig_C1-set,pfam_Ig_V-set,smart_Ig_sub,smart_Ig_C1-set,pfscan_Ig-like_dom	-	no_errors	TAPBPL	HGNC	ENSG00000139192	tier1	-	-	103	0	0.00	107	19	15.08	47	0	0.00	40	2	4.76
FLT4	0	genome.wustl.edu	37	5	180040031	180040031	+	Silent	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	5	180040031	180040031	C	T	SNP	FLT4	ENST00000261937	human	ensembl	74_37	-1	known	silent	c.3411	p.P1137	0.950	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_Ig_I-set,superfamily_Kinase-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom,pfscan_Ig-like_dom,prints_VEGFR3_rcpt	-	no_errors	FLT4	HGNC	ENSG00000037280	tier1	-	-	110	0	0.00	102	19	15.70	27	0	0.00	19	2	9.52
SLC7A9	0	genome.wustl.edu	37	19	33355561	33355561	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	19	33355561	33355561	G	A	SNP	SLC7A9	ENST00000023064	human	ensembl	74_37	-1	known	missense	c.209	p.A70V	0.993	pfam_AA-permease/SLC12A_dom,pirsf_AA/rel_permease1	pfam_AA-permease/SLC12A_dom,pirsf_AA/rel_permease1	-	no_errors	SLC7A9	HGNC	ENSG00000021488	tier1	-	-	110	0	0.00	84	15	15.15	60	0	0.00	45	3	6.25
DSCAM	0	genome.wustl.edu	37	21	41385013	41385013	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	C	C					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	21	41385013	41385013	C	T	SNP	DSCAM	ENST00000400454	human	ensembl	74_37	-1	known	missense	c.5987	p.R1996Q	1.000	NULL	pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,superfamily_Fibronectin_type3,smart_Ig_sub2,smart_Ig_sub,smart_Ig_V-set_subgr,smart_Fibronectin_type3,pfscan_Fibronectin_type3,pfscan_Ig-like_dom	-	no_errors	DSCAM	HGNC	ENSG00000171587	tier1	-	-	28	0	0.00	34	5	12.82	61	0	0.00	56	3	5.08
GLB1	0	genome.wustl.edu	37	3	33058210	33058210	+	Silent	SNP	G	G	A			TCGA-DX-A3M2-01A-21D-A228-09	TCGA-DX-A3M2-10A-01D-A22A-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	4817e957-b838-4898-8074-28a44c974f2b	37354b9e-6333-4411-a61c-a111fe74725a	3	33058210	33058210	G	A	SNP	GLB1	ENST00000445488	human	ensembl	74_37	-1	known	silent	c.1614	p.N538	0.169	superfamily_Galactose-bd-like	pfam_Glycoside_Hdrlase_35,pfam_Glyco_hydro_42_N,superfamily_Glycoside_hydrolase_SF,superfamily_Galactose-bd-like,prints_Glycoside_Hdrlase_35	-	no_errors	GLB1	HGNC	ENSG00000170266	tier1	-	-	62	0	0.00	51	12	19.05	133	0	0.00	93	2	2.08