Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
PCLO	0	genome.wustl.edu	37	7	82784233	82784233	+	Missense_Mutation	SNP	G	G	C			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	7	82784233	82784233	G	C	SNP	PCLO	ENST00000333891	human	ensembl	74_37	-1	known	missense	c.1724	p.S575C	0.665	NULL	pfam_Znf_piccolo,pfam_C2_dom,pfam_PDZ,superfamily_C2_dom,superfamily_PDZ,superfamily_Znf_FYVE_PHD,smart_PDZ,smart_C2_dom,pfscan_C2_dom,pfscan_PDZ	-	no_errors	PCLO	HGNC	ENSG00000186472	tier1	-	-	129	0	0.00	63	47	42.73	78	1	1.27	56	56	50.00
GALNT5	0	genome.wustl.edu	37	2	158115495	158115495	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	2	158115495	158115495	T	G	SNP	GALNT5	ENST00000259056	human	ensembl	74_37	+1	known	missense	c.901	p.L301V	0.000	NULL	pfam_Glyco_trans_2,pfam_Ricin_B_lectin,superfamily_Ricin_B_lectin,smart_Ricin_B_lectin,pfscan_Ricin_B_lectin	-	no_errors	GALNT5	HGNC	ENSG00000136542	tier1	-	-	24	0	0.00	14	8	36.36	105	0	0.00	61	46	42.99
LOC652276	0	genome.wustl.edu	37	16	2653400	2653400	+	R	SNP	C	C	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	16	2653400	2653400	C	G	SNP	LOC652276	ENST00000399702	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.001	-	-	-	no_errors	AC141586.5	Clone_based_vega_gene	ENSG00000215154	tier1	-	-	47	0	0.00	34	20	37.04	90	0	0.00	60	44	42.31
TESPA1	0	genome.wustl.edu	37	12	55354969	55354969	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	55354969	55354969	G	A	SNP	TESPA1	ENST00000316577	human	ensembl	74_37	-1	known	missense	c.1550	p.A517V	0.001	NULL	NULL	-	no_errors	TESPA1	HGNC	ENSG00000135426	tier1	-	-	35	0	0.00	253	81	24.25	98	0	0.00	690	251	26.56
I	0	genome.wustl.edu	37	10	105038013	105038013	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	10	105038013	105038013	G	A	SNP	I	ENST00000369849	human	ensembl	74_37	+1	known	missense	c.1045	p.A349T	0.984	pfam_IF	pfam_IF,pfam_Intermed_filament_D-bd,superfamily_Prefoldin	-	no_errors	I	HGNC	ENSG00000148798	tier1	-	-	51	0	0.00	13	20	60.61	17	0	0.00	12	14	53.85
PTPRC	0	genome.wustl.edu	37	1	198685967	198685967	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	1	198685967	198685967	C	T	SNP	PTPRC	ENST00000442510	human	ensembl	74_37	+1	known	missense	c.1448	p.A483V	0.000	pirsf_Leukocyte_common_ag,superfamily_Fibronectin_type3	pirsf_Leukocyte_common_ag,pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Leukocyte_common_ag,pfam_PTP_recept_N,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,prints_Tyr_Pase_rcpt/non-rcpt,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRC	HGNC	ENSG00000081237	tier1	-	-	51	0	0.00	16	11	40.74	96	0	0.00	53	46	46.46
FAT3	0	genome.wustl.edu	37	11	92534174	92534174	+	Missense_Mutation	SNP	T	T	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	11	92534174	92534174	T	G	SNP	FAT3	ENST00000298047	human	ensembl	74_37	+1	known	missense	c.7995	p.N2665K	0.763	pfam_Cadherin,superfamily_Cadherin-like,smart_Cadherin,pfscan_Cadherin	pfam_Cadherin,pfam_Laminin_G,pfam_EGF-like_Ca-bd_dom,superfamily_ConA-like_lec_gl_sf,superfamily_Cadherin-like,smart_Cadherin,smart_EG-like_dom,smart_Laminin_G,smart_EGF-like_Ca-bd_dom,pfscan_EG-like_dom,pfscan_Laminin_G,pfscan_Cadherin,prints_Cadherin	-	no_errors	FAT3	HGNC	ENSG00000165323	tier1	-	-	47	0	0.00	24	20	45.45	101	0	0.00	52	39	42.86
CEP290	0	genome.wustl.edu	37	12	88505602	88505602	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	88505602	88505602	C	G	SNP	CEP290	ENST00000309041	human	ensembl	74_37	-1	known	missense	c.2092	p.D698H	1.000	NULL	NULL	-	no_errors	CEP290	HGNC	ENSG00000198707	tier1	-	-	62	0	0.00	33	278	89.39	78	0	0.00	52	487	90.02
EPHB2	0	genome.wustl.edu	37	1	23111370	23111370	+	Silent	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	1	23111370	23111370	C	T	SNP	EPHB2	ENST00000400191	human	ensembl	74_37	+1	known	silent	c.612	p.G204	0.239	pirsf_Tyr_kinase_ephrin_rcpt	pirsf_Tyr_kinase_ephrin_rcpt,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Ephrin_rcpt_lig-bd_dom,pfam_Prot_kinase_dom,pfam_Fibronectin_type3,pfam_SAM_type1,pfam_SAM_2,pfam_Tyr-kin_ephrin_A/B_rcpt-like,superfamily_Galactose-bd-like,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_SAM/pointed,superfamily_Growth_fac_rcpt_N_dom,smart_Ephrin_rcpt_lig-bd_dom,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_SAM,pfscan_Fibronectin_type3,pfscan_SAM,pfscan_Prot_kinase_dom,prints_Ser-Thr/Tyr_kinase_cat_dom	-	no_errors	EPHB2	HGNC	ENSG00000133216	tier1	-	-	64	0	0.00	62	7	10.14	31	0	0.00	28	5	15.15
ZHX3	0	genome.wustl.edu	37	20	39833134	39833134	+	Silent	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	20	39833134	39833134	G	A	SNP	ZHX3	ENST00000309060	human	ensembl	74_37	-1	known	silent	c.423	p.N141	0.974	NULL	pfam_Homeobox_dom,superfamily_Homeodomain-like,smart_Znf_C2H2-like,smart_Homeobox_dom,pfscan_Homeobox_dom	-	no_errors	ZHX3	HGNC	ENSG00000174306	tier1	rs113667928	-	33	0	0.00	14	14	50.00	59	0	0.00	29	28	48.28
SERPINB1	0	genome.wustl.edu	37	6	2840713	2840713	+	Silent	SNP	T	T	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	T	T	T	G	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	6	2840713	2840713	T	G	SNP	SERPINB1	ENST00000380739	human	ensembl	74_37	-1	known	silent	c.108	p.S36	0.029	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	pfam_Serpin_dom,superfamily_Serpin_dom,smart_Serpin_dom	-	no_errors	SERPINB1	HGNC	ENSG00000021355	tier1	-	-	79	0	0.00	57	24	29.63	76	0	0.00	48	49	50.52
CEP290	0	genome.wustl.edu	37	12	88505548	88505548	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	88505548	88505548	C	T	SNP	CEP290	ENST00000309041	human	ensembl	74_37	-1	known	missense	c.2146	p.E716K	1.000	NULL	NULL	-	no_errors	CEP290	HGNC	ENSG00000198707	tier1	-	-	81	0	0.00	41	368	89.98	99	1	1.00	51	599	92.15
FSTL4	0	genome.wustl.edu	37	5	132545944	132545944	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	5	132545944	132545944	G	A	SNP	FSTL4	ENST00000265342	human	ensembl	74_37	-1	known	missense	c.1655	p.S552L	1.000	NULL	pfam_Ig_I-set,pfam_Immunoglobulin,pfam_Kazal_dom,smart_Kazal_dom,smart_Ig_sub,smart_Ig_sub2,pfscan_EF_hand_dom,pfscan_Ig-like_dom	-	no_errors	FSTL4	HGNC	ENSG00000053108	tier1	-	-	52	0	0.00	17	20	54.05	53	0	0.00	32	37	53.62
ENSG00000229481	0	genome.wustl.edu	37	19	38321280	38321280	+	R	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	19	38321280	38321280	C	T	SNP	ENSG00000229481	ENST00000443870	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.096	-	-	-	no_errors	CTD-2554C21.3	Clone_based_vega_gene	ENSG00000229481	tier1	-	-	75	0	0.00	33	33	50.00	108	0	0.00	65	69	51.49
TRIM9	0	genome.wustl.edu	37	14	51446051	51446051	+	Silent	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	14	51446051	51446051	C	T	SNP	TRIM9	ENST00000338969	human	ensembl	74_37	-1	known	silent	c.2367	p.R789	0.310	NULL	pfam_SPRY_rcpt,pfam_Fibronectin_type3,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,superfamily_Fibronectin_type3,superfamily_Znf_FYVE_PHD,smart_Znf_RING,smart_Znf_B-box,smart_Bbox_C,smart_Fibronectin_type3,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Fibronectin_type3,pfscan_Znf_B-box,pfscan_Znf_RING	-	no_errors	TRIM9	HGNC	ENSG00000100505	tier1	-	-	68	0	0.00	23	12	34.29	79	0	0.00	49	44	47.31
DH12	0	genome.wustl.edu	37	3	57443570	57443570	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	3	57443570	57443570	G	A	SNP	DH12	ENST00000351747	human	ensembl	74_37	-1	known	nonsense	c.3145	p.R1049*	1.000	pfam_Dynein_heavy_dom-2	pfam_Dynein_heavy_dom,pfam_Dynein_heavy_dom-2,pfam_ATPase_dyneun-rel_AAA,superfamily_P-loop_NTPase,smart_AAA+_ATPase	-	no_errors	DH12	HGNC	ENSG00000174844	tier1	-	-	58	0	0.00	19	16	45.71	73	0	0.00	48	45	48.39
ENSG00000259966	0	genome.wustl.edu	37	16	32618890	32618890	+	R	SNP	G	G	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	16	32618890	32618890	G	T	SNP	ENSG00000259966	ENST00000562976	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.000	-	-	-	no_errors	RP11-652G5.1	Clone_based_vega_gene	ENSG00000259966	tier1	-	-	56	0	0.00	38	20	34.48	14	0	0.00	11	9	45.00
AK7	0	genome.wustl.edu	37	14	96875257	96875257	+	Silent	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	14	96875257	96875257	G	A	SNP	AK7	ENST00000267584	human	ensembl	74_37	+1	known	silent	c.477	p.A159	0.372	NULL	pfam_Dpy-30_motif,pfam_Adenylate_kin,superfamily_P-loop_NTPase	-	no_errors	AK7	HGNC	ENSG00000140057	tier1	-	-	71	0	0.00	196	23	10.50	84	0	0.00	337	49	12.69
REV3L	0	genome.wustl.edu	37	6	111680107	111680107	+	Silent	SNP	A	A	C			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	A	A	A	C	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	6	111680107	111680107	A	C	SNP	REV3L	ENST00000358835	human	ensembl	74_37	-1	known	silent	c.6990	p.S2330	0.996	pfam_D-dir_D_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_B	pfam_D-dir_D_pol_B_multi_dom,pfam_D-dir_D_pol_B_exonuc,superfamily_RNaseH-like_dom,smart_D-dir_D_pol_B,prints_D-dir_D_pol_B	-	no_errors	REV3L	HGNC	ENSG00000009413	tier1	-	-	57	0	0.00	25	11	30.56	93	0	0.00	68	50	42.37
LRP1	0	genome.wustl.edu	37	12	57572170	57572170	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	57572170	57572170	G	T	SNP	LRP1	ENST00000243077	human	ensembl	74_37	+1	known	missense	c.4390	p.D1464Y	1.000	smart_LDLR_classB_rpt,pfscan_LDLR_classB_rpt	pfam_LDrepeatLR_classA_rpt,pfam_LDLR_classB_rpt,superfamily_Growth_fac_rcpt_N_dom,superfamily_LDrepeatLR_classA_rpt,smart_LDrepeatLR_classA_rpt,smart_EGF-like_Ca-bd_dom,smart_EG-like_dom,smart_LDLR_classB_rpt,pfscan_EG-like_dom,pfscan_LDrepeatLR_classA_rpt,pfscan_LDLR_classB_rpt,prints_LDrepeatLR_classA_rpt	-	no_errors	LRP1	HGNC	ENSG00000123384	tier1	-	-	53	0	0.00	230	112	32.75	45	0	0.00	309	131	29.77
RGR	0	genome.wustl.edu	37	10	86007502	86007502	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	10	86007502	86007502	C	T	SNP	RGR	ENST00000359452	human	ensembl	74_37	+1	known	missense	c.235	p.R79C	1.000	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM	pfam_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_7TM,prints_RPE_GPCR,prints_GPCR_Rhodpsn	-	no_errors	RGR	HGNC	ENSG00000148604	tier1	rs201335015	-	69	0	0.00	30	17	36.17	62	0	0.00	26	16	38.10
SYNM	0	genome.wustl.edu	37	15	99673642	99673642	+	R	SNP	G	G	C			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	C	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	15	99673642	99673642	G	C	SNP	SYNM	ENST00000558420	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.008	-	-	-	no_errors	SYNM	HGNC	ENSG00000182253	tier1	-	-	20	0	0.00	10	9	47.37	59	0	0.00	36	46	56.10
PLEKHG4B	0	genome.wustl.edu	37	5	173084	173084	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	5	173084	173084	C	G	SNP	PLEKHG4B	ENST00000283426	human	ensembl	74_37	+1	known	missense	c.3055	p.L1019V	1.000	smart_Pleckstrin_homology,pfscan_Pleckstrin_homology	pfam_DH-domain,superfamily_DH-domain,superfamily_CRAL-TRIO_dom,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PLEKHG4B	HGNC	ENSG00000153404	tier1	-	-	117	1	0.85	86	369	81.10	87	0	0.00	110	502	82.03
MBD6	0	genome.wustl.edu	37	12	57918117	57918117	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	57918117	57918117	G	A	SNP	MBD6	ENST00000355673	human	ensembl	74_37	+1	known	missense	c.31	p.D11N	1.000	superfamily_D-bd_dom,pfscan_Methyl_CpG_D-bd	superfamily_D-bd_dom,smart_Methyl_CpG_D-bd,pfscan_Methyl_CpG_D-bd	-	no_errors	MBD6	HGNC	ENSG00000166987	tier1	-	-	56	0	0.00	524	116	18.12	37	0	0.00	337	70	17.16
MET	0	genome.wustl.edu	37	7	116371840	116371840	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	7	116371840	116371840	C	T	SNP	MET	ENST00000318493	human	ensembl	74_37	+1	known	missense	c.1319	p.T440I	1.000	pirsf_Tyr_kinase_HGF/MSP_rcpt,pfam_Semap_dom,superfamily_Semap_dom,smart_Semap_dom,pfscan_Semap_dom	pirsf_Tyr_kinase_HGF/MSP_rcpt,pfam_Semap_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Prot_kinase_dom,pfam_IPT,pfam_Plexin_repeat,superfamily_Semap_dom,superfamily_Kinase-like_dom,superfamily_Ig_E-set,superfamily_Plexin-like_fold,smart_Semap_dom,smart_Plexin-like_fold,smart_IPT,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,prints_Ser-Thr/Tyr_kinase_cat_dom,pfscan_Semap_dom,pfscan_Prot_kinase_dom	-	no_errors	MET	HGNC	ENSG00000105976	tier1	-	-	69	0	0.00	44	17	27.87	66	0	0.00	58	22	27.50
TRIM22	0	genome.wustl.edu	37	11	5730822	5730822	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	11	5730822	5730822	T	C	SNP	TRIM22	ENST00000379965	human	ensembl	74_37	+1	known	missense	c.1441	p.Y481H	0.976	pfam_SPRY_rcpt,superfamily_ConA-like_lec_gl_sf,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,prints_Butyrophylin	pfam_SPRY_rcpt,pfam_Znf_B-box,pfam_Znf_C3HC4_RING-type,superfamily_ConA-like_lec_gl_sf,smart_Znf_RING,smart_Znf_B-box,smart_SPla/RYanodine_receptor_subgr,pfscan_B30.2/SPRY,pfscan_Znf_B-box,pfscan_Znf_RING,prints_Butyrophylin	-	no_errors	TRIM22	HGNC	ENSG00000132274	tier1	-	-	39	0	0.00	28	16	36.36	61	0	0.00	31	40	56.34
CCT2	0	genome.wustl.edu	37	12	69986852	69986852	+	Missense_Mutation	SNP	C	C	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	G	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	69986852	69986852	C	G	SNP	CCT2	ENST00000299300	human	ensembl	74_37	+1	known	missense	c.847	p.L283V	1.000	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,tigrfam_Chap_CCT_beta	pfam_Cpn60/TCP-1,superfamily_Cpn60/TCP-1,superfamily_GroEL-like_apical_dom,prints_Chaperone_TCP-1,prints_Chaprnin_Cpn60,tigrfam_Chap_CCT_beta	-	no_errors	CCT2	HGNC	ENSG00000166226	tier1	-	-	63	0	0.00	29	219	88.31	121	0	0.00	83	438	84.07
CHN1	0	genome.wustl.edu	37	2	175666532	175666532	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	2	175666532	175666532	C	A	SNP	CHN1	ENST00000409900	human	ensembl	74_37	-1	known	missense	c.1111	p.D371Y	1.000	pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pirsf_N-chimaerin,pfscan_RhoGAP_dom	pfam_RhoGAP_dom,pfam_Prot_Kinase_C-like_PE/DAG-bd,pfam_SH2,superfamily_Rho_GTPase_activation_prot,smart_SH2,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_RhoGAP_dom,pirsf_N-chimaerin,pfscan_SH2,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_RhoGAP_dom,prints_DAG/PE-bd	-	no_errors	CHN1	HGNC	ENSG00000128656	tier1	-	-	51	0	0.00	25	16	39.02	66	0	0.00	71	40	36.04
RASGRF1	0	genome.wustl.edu	37	15	79292172	79292172	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	15	79292172	79292172	C	T	SNP	RASGRF1	ENST00000419573	human	ensembl	74_37	-1	known	missense	c.2707	p.A903T	0.971	pfam_Ras-like_Gua-exchang_fac_N,superfamily_Ras_GEF_dom,smart_Ras-like_Gua-exchang_fac_N	pfam_RasGRF_CDC25,pfam_Ras-like_Gua-exchang_fac_N,pfam_DH-domain,pfam_Pleckstrin_homology,superfamily_Ras_GEF_dom,superfamily_DH-domain,smart_Pleckstrin_homology,smart_DH-domain,smart_Ras-like_Gua-exchang_fac_N,smart_RasGRF_CDC25,pfscan_IQ_motif_EF-hand-BS,pfscan_Pleckstrin_homology,pfscan_DH-domain,pfscan_RasGRF_CDC25,pfscan_Ras-like_Gua-exchang_fac_N	-	no_errors	RASGRF1	HGNC	ENSG00000058335	tier1	rs199661393	-	78	0	0.00	90	37	29.13	64	0	0.00	57	31	35.23
PAN2	0	genome.wustl.edu	37	12	56718437	56718437	+	Silent	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	12	56718437	56718437	C	T	SNP	PAN2	ENST00000425394	human	ensembl	74_37	-1	known	silent	c.1656	p.K552	1.000	pfam_Peptidase_C19/C67,pfscan_Peptidase_C19/C67	pfam_Exonuclease_RNaseT/D_pol3,pfam_Peptidase_C19/C67,superfamily_RNaseH-like_dom,superfamily_WD40_repeat_dom,smart_Exonuclease,pfscan_Peptidase_C19/C67	-	no_errors	PAN2	HGNC	ENSG00000135473	tier1	-	-	55	0	0.00	343	35	9.26	61	0	0.00	524	95	15.32
PTPRH	0	genome.wustl.edu	37	19	55715272	55715272	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	19	55715272	55715272	C	T	SNP	PTPRH	ENST00000376350	human	ensembl	74_37	-1	known	missense	c.764	p.R255Q	0.000	pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,pfscan_Fibronectin_type3	pfam_Tyr_Pase_rcpt/non-rcpt,pfam_Fibronectin_type3,superfamily_Fibronectin_type3,smart_Fibronectin_type3,smart_Tyr_Pase_rcpt/non-rcpt,smart_Tyr_Pase_cat,pfscan_Fibronectin_type3,pfscan_Tyr/Dual-sp_Pase,pfscan_Tyr_Pase_rcpt/non-rcpt,prints_Tyr_Pase_rcpt/non-rcpt	-	no_errors	PTPRH	HGNC	ENSG00000080031	tier1	rs199739996	-	116	0	0.00	43	27	38.57	83	0	0.00	56	22	28.21
NRD1	0	genome.wustl.edu	37	1	52264037	52264037	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	1	52264037	52264037	C	T	SNP	NRD1	ENST00000354831	human	ensembl	74_37	-1	known	missense	c.2692	p.D898N	1.000	superfamily_Metalloenz_LuxS/M16	pfam_Pept_M16_N,pfam_Peptidase_M16_C,superfamily_Metalloenz_LuxS/M16	-	no_errors	NRD1	HGNC	ENSG00000078618	tier1	-	-	26	0	0.00	30	175	85.37	81	0	0.00	113	737	86.50
FER1L6	0	genome.wustl.edu	37	8	125113350	125113350	+	Silent	SNP	C	C	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	8	125113350	125113350	C	A	SNP	FER1L6	ENST00000399018	human	ensembl	74_37	+1	known	silent	c.4896	p.G1632	0.012	pfam_C2_dom,superfamily_C2_dom,smart_C2_dom,pfscan_C2_dom	pfam_C2_dom,pfam_Ferlin_B-domain,pfam_FerIin-domain,superfamily_C2_dom,superfamily_ABC1_TM_dom,smart_C2_dom,pfscan_C2_dom	-	no_errors	FER1L6	HGNC	ENSG00000214814	tier1	-	-	30	0	0.00	22	14	38.89	45	0	0.00	66	37	35.92
L1TD1	0	genome.wustl.edu	37	1	62672850	62672850	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	1	62672850	62672850	A	G	SNP	L1TD1	ENST00000498273	human	ensembl	74_37	+1	known	missense	c.550	p.R184G	0.001	NULL	pfam_Transposase_22,superfamily_STAT_TF_coiled-coil	-	no_errors	L1TD1	HGNC	ENSG00000240563	tier1	-	-	34	0	0.00	62	7	10.14	90	0	0.00	289	40	12.16
SPN	0	genome.wustl.edu	37	16	29675786	29675786	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	16	29675786	29675786	G	A	SNP	SPN	ENST00000360121	human	ensembl	74_37	+1	known	missense	c.737	p.R246Q	0.000	NULL	NULL	-	no_errors	SPN	HGNC	ENSG00000197471	tier1	rs181483014	GMAF=0.0005	107	0	0.00	51	37	42.05	71	0	0.00	38	20	34.48
RSPH6A	0	genome.wustl.edu	37	19	46303816	46303816	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	19	46303816	46303816	T	C	SNP	RSPH6A	ENST00000221538	human	ensembl	74_37	-1	known	missense	c.1804	p.M602V	0.106	pfam_Radial_spoke	pfam_Radial_spoke	-	no_errors	RSPH6A	HGNC	ENSG00000104941	tier1	-	-	157	0	0.00	71	34	32.38	32	0	0.00	24	17	41.46
CLVS1	0	genome.wustl.edu	37	8	62371079	62371081	+	In_Frame_Del	DEL	TGC	TGC	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	TGC	TGC	TGC	-	TGC	TGC	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	8	62371079	62371081	TGC	-	DEL	CLVS1	ENST00000325897	human	ensembl	74_37	+1	known	in_frame_del	c.955_957	p.C319in_frame_del	0.586:0.792:0.937	NULL	pfam_CRAL-TRIO_dom,pfam_CRAL/TRIO_N_dom,superfamily_CRAL-TRIO_dom,superfamily_CRAL/TRIO_N_dom,smart_CRAL-TRIO_dom,pfscan_CRAL-TRIO_dom,prints_CRAL-bd_toc_tran	-	no_errors	CLVS1	HGNC	ENSG00000177182	tier1			42	0	0.00	22	21	48.84	72	0	0.00	39	19	32.76
WDR61	0	genome.wustl.edu	37	15	78575602	78575608	+	R	DEL	AAGTATG	AAGTATG	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	AAGTATG	AAGTATG	AAGTATG	-	AAGTATG	AAGTATG	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	15	78575602	78575608	AAGTATG	-	DEL	WDR61	ENST00000559332	human	ensembl	74_37	-1	putative	rna	NULL	NULL	0.044:0.027:0.020:0.017:0.024:0.039:0.066	-	-	-	no_errors	WDR61	HGNC	ENSG00000140395	tier1			96	0	0.00	66	24	26.67	96	0	0.00	66	24	26.67
ARL13B	0	genome.wustl.edu	37	3	93769680	93769680	+	Frame_Shift_Del	DEL	C	C	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	C	C	C	-	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	3	93769680	93769680	C	-	DEL	ARL13B	ENST00000394222	human	ensembl	74_37	+1	known	frame_shift_del	c.1154	p.P386fs	1.000	NULL	pfam_Small_GTPase_ARF/SAR,pfam_Small_GTPase,pfam_SRP_receptor_beta_su,superfamily_P-loop_NTPase,smart_Small_GTPase_ARF,smart_Small_GTPase_SAR1,prints_Small_GTPase_ARF/SAR,tigrfam_Small_GTP-bd_dom	-	no_errors	ARL13B	HGNC	ENSG00000169379	tier1			33	0	0.00	15	14	48.28	76	0	0.00	55	26	32.10
DCTN4	0	genome.wustl.edu	37	5	150097914	150097914	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	5	150097914	150097914	G	-	DEL	DCTN4	ENST00000446090	human	ensembl	74_37	-1	known	frame_shift_del	c.1016	p.P339fs	1.000	pfam_Dynactin_p62	pfam_Dynactin_p62	-	no_errors	DCTN4	HGNC	ENSG00000132912	tier1			62	0	0.00	31	17	35.42	75	0	0.00	64	26	28.89
DERL3	0	genome.wustl.edu	37	22	24176678	24176700	+	R	DEL	CAACAGGTCATGTTCAATTTCTT	CAACAGGTCATGTTCAATTTCTT	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	CAACAGGTCATGTTCAATTTCTT	CAACAGGTCATGTTCAATTTCTT	CAACAGGTCATGTTCAATTTCTT	-	CAACAGGTCATGTTCAATTTCTT	CAACAGGTCATGTTCAATTTCTT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	22	24176678	24176700	CAACAGGTCATGTTCAATTTCTT	-	DEL	DERL3	ENST00000464023	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.881:0.744:0.541:0.169:0.191:0.247:0.273:0.214:0.004:0.003:0.003:0.004:0.017:0.025:0.031:0.034:0.036:0.045:0.051:0.010:0.016:0.016:0.010	-	-	-	no_errors	DERL3	HGNC	ENSG00000099958	tier1			77	1	1.28	19	3	13.64	77	1	1.28	19	3	13.64
DPH6	0	genome.wustl.edu	37	15	35746987	35746987	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	15	35746987	35746987	G	T	SNP	DPH6	ENST00000256538	human	ensembl	74_37	-1	known	missense	c.347	p.A116D	1.000	pfam_DUF71_dom,tigrfam_DUF71_dom	pfam_DUF71_dom,tigrfam_DUF71_dom	-	no_errors	DPH6	HGNC	ENSG00000134146	tier1	-	-	11	0	0.00	2	10	83.33	44	0	0.00	3	27	90.00
EFHD2	0	genome.wustl.edu	37	1	15753676	15753676	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	1	15753676	15753676	G	A	SNP	EFHD2	ENST00000375980	human	ensembl	74_37	+1	known	missense	c.487	p.G163R	1.000	pfscan_EF_hand_dom	smart_EF_hand_dom,pfscan_EF_hand_dom	-	no_errors	EFHD2	HGNC	ENSG00000142634	tier1	-	-	34	0	0.00	14	16	53.33	15	0	0.00	1	5	83.33
HNRNPDL	0	genome.wustl.edu	37	4	83350511	83350511	+	Silent	SNP	G	G	A			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	4	83350511	83350511	G	A	SNP	HNRNPDL	ENST00000295470	human	ensembl	74_37	-1	known	silent	c.333	p.H111	0.080	NULL	pfam_RRM_dom,smart_RRM_dom,pfscan_RRM_dom	-	no_errors	HNRNPDL	HGNC	ENSG00000152795	tier1	-	-	74	0	0.00	12	32	69.57	18	0	0.00	1	9	90.00
AK7	0	genome.wustl.edu	37	14	96909100	96909100	+	Frame_Shift_Del	DEL	G	G	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G	G	-	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	14	96909100	96909100	G	-	DEL	AK7	ENST00000267584	human	ensembl	74_37	+1	known	frame_shift_del	c.724	p.V242fs	0.377	NULL	pfam_Dpy-30_motif,pfam_Adenylate_kin,superfamily_P-loop_NTPase	-	no_errors	AK7	HGNC	ENSG00000140057	tier1			122	0	0.00	320	48	13.04	87	0	0.00	429	44	9.30
EHD2	0	genome.wustl.edu	37	19	48244692	48244693	+	R	INS	-	-	G			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	19	48244692	48244693	-	G	INS	EHD2	ENST00000540884	human	ensembl	74_37	+1	known	rna	NULL	NULL	0.938:0.089	-	-	-	no_errors	EHD2	HGNC	ENSG00000024422	tier1			12	0	0.00	12	4	25.00	2	0	0.00	0	0	0.00
ENSG00000216191	0	genome.wustl.edu	37	2	50923314	50923319	+	R	DEL	GTGTGT	GTGTGT	-			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	GTGTGT	GTGTGT					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	2	50923314	50923319	GTGTGT	-	DEL	ENSG00000216191	ENST00000401372	human	ensembl	74_37	-1	novel	rna	NULL	NULL	0.006:0.004:0.003:0.002:0.002:0.000	-	-	-	no_errors	AC009234.2	Clone_based_ensembl_gene	ENSG00000216191	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
ENSG00000259455	0	genome.wustl.edu	37	15	23406924	23406924	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A2IZ-01A-11D-A21Q-09	TCGA-DX-A2IZ-10A-01D-A21Q-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	67bb70b2-b6f8-4aa9-80ce-48829f9fec56	9dc2fa01-ef68-44ce-98d0-dddcb6ef4f46	15	23406924	23406924	G	T	SNP	ENSG00000259455	ENST00000558241	human	ensembl	74_37	-1	novel	missense	c.1912	p.Q638K	0.078	NULL	superfamily_Ribosomal_L7/12_C/ClpS-like,prints_Tropomyosin	-	no_errors	RP11-467N20.5	Clone_based_vega_gene	ENSG00000259455	tier1	-	-	233	0	0.00	153	53	25.73	2	0	0.00	2	0	0.00