Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	default_gene_name	gene_name_source	 ensembl_gene_id	tier	dbSNP	GMAF	n_ref_count	n_alt_count	normal_vaf	t_ref_count	t_alt_count	tumor_vaf	n_ref_count_val	n_alt_count_val	normal_vaf_val	t_ref_count_val	t_alt_count_val	tumor_vaf_val
TTC23	0	genome.wustl.edu	37	15	99759242	99759242	+	Missense_Mutation	SNP	G	G	T			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G	G	T	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	15	99759242	99759242	G	T	SNP	TTC23	ENST00000262074	human	ensembl	74_37	-1	known	missense	c.316	p.Q106K	0.998	smart_TPR_repeat	smart_TPR_repeat	-	no_errors	TTC23	HGNC	ENSG00000103852	tier1	-	-	18	0	0.00	46	15	24.59	62	0	0.00	114	31	21.23
TRAF7	0	genome.wustl.edu	37	16	2225556	2225556	+	Missense_Mutation	SNP	A	A	G			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	A	A	A	G	A	A	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	16	2225556	2225556	A	G	SNP	TRAF7	ENST00000326181	human	ensembl	74_37	+1	known	missense	c.1559	p.N520S	1.000	pfam_WD40_repeat,superfamily_WD40_repeat_dom,smart_WD40_repeat,pfscan_WD40_repeat_dom	pfam_WD40_repeat,superfamily_WD40_repeat_dom,superfamily_TRAF-like,smart_Znf_RING,smart_WD40_repeat,pfscan_Znf_RING,pfscan_Znf_TRAF,pfscan_WD40_repeat,pfscan_WD40_repeat_dom,prints_G-protein_beta_WD-40_rep	-	no_errors	TRAF7	HGNC	ENSG00000131653	tier1	-	-	13	0	0.00	17	6	26.09	58	0	0.00	49	7	12.50
STAB2	0	genome.wustl.edu	37	12	104092880	104092880	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	12	104092880	104092880	G	A	SNP	STAB2	ENST00000388887	human	ensembl	74_37	+1	known	missense	c.3589	p.D1197N	0.018	pfam_FAS1_domain,superfamily_FAS1_domain,superfamily_Growth_fac_rcpt_N_dom,smart_FAS1_domain,pfscan_FAS1_domain	pfam_FAS1_domain,pfam_Link,superfamily_C-type_lectin_fold,superfamily_FAS1_domain,superfamily_Growth_fac_rcpt_N_dom,smart_EG-like_dom,smart_EGF_laminin,smart_EGF-like_Ca-bd_dom,smart_FAS1_domain,smart_Link,pfscan_EG-like_dom,pfscan_FAS1_domain,pfscan_Link	-	no_errors	STAB2	HGNC	ENSG00000136011	tier1	-	-	36	0	0.00	77	326	80.89	60	0	0.00	106	339	76.01
MON2	0	genome.wustl.edu	37	12	62949949	62949949	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	12	62949949	62949949	G	A	SNP	MON2	ENST00000393630	human	ensembl	74_37	+1	known	missense	c.3389	p.R1130K	1.000	superfamily_ARM-type_fold	pfam_DUF1981_Sec7_assoc,superfamily_ARM-type_fold	-	no_errors	MON2	HGNC	ENSG00000061987	tier1	-	-	14	0	0.00	34	68	66.67	69	0	0.00	86	151	63.71
PLEKHG2	0	genome.wustl.edu	37	19	39911414	39911414	+	Silent	SNP	C	C	T			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	19	39911414	39911414	C	T	SNP	PLEKHG2	ENST00000409794	human	ensembl	74_37	+1	known	silent	c.1321	p.L441	0.984	NULL	pfam_DH-domain,superfamily_DH-domain,smart_DH-domain,smart_Pleckstrin_homology,pfscan_Pleckstrin_homology,pfscan_DH-domain	-	no_errors	PLEKHG2	HGNC	ENSG00000090924	tier1	-	-	33	0	0.00	36	5	12.20	133	0	0.00	131	18	12.08
CAC1G	0	genome.wustl.edu	37	17	48646553	48646553	+	Missense_Mutation	SNP	T	T	C			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	T	T	T	C	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	17	48646553	48646553	T	C	SNP	CAC1G	ENST00000359106	human	ensembl	74_37	+1	known	missense	c.382	p.F128L	1.000	pfam_Ion_trans_dom	pfam_Ion_trans_dom,pfam_PKD1_2_channel,prints_VDCC_T_a1su,prints_VDCCAlpha1	-	no_errors	CAC1G	HGNC	ENSG00000006283	tier1	-	-	103	0	0.00	155	16	9.36	115	0	0.00	113	13	10.24
HLA-F	0	genome.wustl.edu	37	6	29692901	29692901	+	Missense_Mutation	SNP	C	C	T			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	C	C	C	T	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	6	29692901	29692901	C	T	SNP	HLA-F	ENST00000259951	human	ensembl	74_37	+1	known	missense	c.704	p.T235M	0.675	pfam_Ig_C1-set,smart_Ig_C1-set,pfscan_Ig-like_dom	pfam_MHC_I_a_a1/a2,pfam_Ig_C1-set,superfamily_MHC_I/II-like_Ag-recog,smart_Ig_C1-set,pfscan_Ig-like_dom,prints_MHC_I_a	-	no_errors	HLA-F	HGNC	ENSG00000204642	tier1	-	-	90	0	0.00	144	26	15.20	29	0	0.00	29	4	12.12
ALOX12B	0	genome.wustl.edu	37	17	7989357	7989357	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	17	7989357	7989357	G	A	SNP	ALOX12B	ENST00000319144	human	ensembl	74_37	-1	known	missense	c.329	p.T110I	0.921	pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,pfscan_PLAT/LH2_dom	pfam_LipOase_C,pfam_PLAT/LH2_dom,superfamily_LipOase_C,superfamily_Lipase_LipOase,smart_PLAT/LH2_dom,pfscan_PLAT/LH2_dom,prints_LipOase_C,prints_LipOase_mml	-	no_errors	ALOX12B	HGNC	ENSG00000179477	tier1	-	-	26	0	0.00	52	5	8.77	74	0	0.00	69	4	5.48
ADTRP	0	genome.wustl.edu	37	6	11714728	11714728	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G	G	A	G	G	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	6	11714728	11714728	G	A	SNP	ADTRP	ENST00000229583	human	ensembl	74_37	-1	known	missense	c.730	p.R244W	0.000	NULL	pfam_Far-17a_AIG1	-	no_errors	ADTRP	HGNC	ENSG00000111863	tier1	-	-	77	0	0.00	111	13	10.48	96	0	0.00	135	11	7.53
CDC7	0	genome.wustl.edu	37	1	91977217	91977217	+	Silent	SNP	T	T	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	T	T	T	A	T	T	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	1	91977217	91977217	T	A	SNP	CDC7	ENST00000234626	human	ensembl	74_37	+1	known	silent	c.399	p.A133	0.984	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	pfam_Prot_kinase_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_dom	-	no_errors	CDC7	HGNC	ENSG00000097046	tier1	-	-	43	0	0.00	91	10	9.90	106	0	0.00	121	8	6.20
NPVF	0	genome.wustl.edu	37	7	25266594	25266594	+	Missense_Mutation	SNP	C	C	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	C	C	C	A	C	C	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	7	25266594	25266594	C	A	SNP	NPVF	ENST00000222674	human	ensembl	74_37	-1	known	missense	c.190	p.D64Y	1.000	NULL	NULL	-	no_errors	NPVF	HGNC	ENSG00000105954	tier1	-	-	47	0	0.00	75	11	12.79	127	0	0.00	129	11	7.86
TRPM1	0	genome.wustl.edu	37	15	31294794	31294797	+	Frame_Shift_Del	DEL	TTCT	TTCT	-			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	TTCT	TTCT	TTCT	-	TTCT	TTCT	Unknown	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	15	31294794	31294797	TTCT	-	DEL	TRPM1	ENST00000542188	human	ensembl	74_37	-1	known	frame_shift_del	c.4160_4157	p.K1386fs	0.000:0.000:0.002:0.002	NULL	pfam_Ion_trans_dom	-	no_errors	TRPM1	HGNC	ENSG00000134160	tier1			34	0	0.00	36	6	14.29	113	0	0.00	119	10	7.75
ENSG00000203849	0	genome.wustl.edu	37	1	142620676	142620678	+	R	DEL	ATA	ATA	-			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	ATA	ATA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	1	142620676	142620678	ATA	-	DEL	ENSG00000203849	ENST00000369381	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.222:0.217:0.212	-	-	-	no_errors	RP11-417J8.6	Clone_based_vega_gene	ENSG00000203849	tier1			19	0	0.00	18	3	14.29	0	0	0.00	0	0	0.00
MT-RNR2	0	genome.wustl.edu	37	MT	2226	2226	+	R	SNP	T	T	C			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	T	T					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	MT	2226	2226	T	C	SNP	MT-RNR2	ENST00000387347	human	ensembl	74_37	+1	known	rna	NULL	NULL	NULL	-	-	-	no_errors	MT-RNR2	HGNC	ENSG00000210082	tier1	-	-	49	0	0.00	75	8	9.64	2	0	0.00	0	0	0.00
PCOLCE2	0	genome.wustl.edu	37	3	142607822	142607823	+	R	INS	-	-	GCTCACACTGGCAGCAGCGCTG			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	-	-					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	3	142607822	142607823	-	GCTCACACTGGCAGCAGCGCTG	INS	PCOLCE2	ENST00000461818	human	ensembl	74_37	-1	known	rna	NULL	NULL	0.000:0.000	-	-	-	no_errors	PCOLCE2	HGNC	ENSG00000163710	tier1			0	0	0.00	0	0	0.00	0	0	0.00	0	0	0.00
SRPX	0	genome.wustl.edu	37	X	38079976	38079978	+	In_Frame_Del	DEL	GCA	GCA	-			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	GCA	GCA					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	X	38079976	38079978	GCA	-	DEL	SRPX	ENST00000378533	human	ensembl	74_37	-1	known	in_frame_del	c.70_68	p.L23in_frame_del	0.000:0.001:0.002	NULL	pfam_Hyalin,pfam_Sushi_SCR_CCP,superfamily_Sushi_SCR_CCP,smart_Sushi_SCR_CCP,pfscan_Hyalin,pfscan_Sushi_SCR_CCP	-	no_errors	SRPX	HGNC	ENSG00000101955	tier1			10	0	0.00	20	2	9.09	0	0	0.00	0	0	0.00
KLHL18	0	genome.wustl.edu	37	3	47385390	47385390	+	Missense_Mutation	SNP	G	G	A			TCGA-DX-A1L4-01A-12D-A26G-09	TCGA-DX-A1L4-10A-01D-A26G-09	G	G					Unknown	Untested	Somatic	Phase_IV	WXS	none			Illumina HiSeq	6c1aa1b8-f02c-43e7-a410-cc0344f0107e	6c11585a-6ac8-4f59-90c4-cae54eb89e0e	3	47385390	47385390	G	A	SNP	KLHL18	ENST00000232766	human	ensembl	74_37	+1	known	missense	c.1684	p.G562R	1.000	smart_Kelch_1,pirsf_Kelch-like_gigaxonin	pfam_Kelch_1,pfam_Kelch_2,pfam_BACK,pfam_BTB_POZ,superfamily_BTB/POZ_fold,smart_BTB/POZ-like,smart_BACK,smart_Kelch_1,pirsf_Kelch-like_gigaxonin,pfscan_BTB/POZ-like	-	no_errors	KLHL18	HGNC	ENSG00000114648	tier1	-	-	12	0	0.00	37	7	15.91	48	0	0.00	41	2	4.65