Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HMGB3	3149	broad.mit.edu	37	X	150156360	150156360	+	Silent	SNP	G	G	A			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chrX:150156360G>A	ENST00000325307.7	+	5	672	c.576G>A	c.(574-576)gaG>gaA	p.E192E	HMGB3_ENST00000448905.2_Silent_p.E192E	NM_005342.2	NP_005333.2	O15347	HMGB3_HUMAN	high mobility group box 3	192	Asp/Glu-rich (acidic).				DNA recombination|multicellular organismal development	chromosome|nucleus	DNA bending activity|double-stranded DNA binding	p.E192E(1)		endometrium(3)|large_intestine(2)|lung(2)|skin(1)	8	Acute lymphoblastic leukemia(192;6.56e-05)					aggaagaagaggaggaggagg	0.443000													4	122					0	0	1	0	0
HRAS	3265	broad.mit.edu	37	11	533874	533874	+	Missense_Mutation	SNP	T	T	C	rs121913233		TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr11:533874T>C	ENST00000417302.1	-	3	369	c.182A>G	c.(181-183)cAg>cGg	p.Q61R	HRAS_ENST00000451590.1_Missense_Mutation_p.Q61R|HRAS_ENST00000397594.1_Missense_Mutation_p.Q61R|HRAS_ENST00000468682.2_5'UTR|HRAS_ENST00000397596.2_Missense_Mutation_p.Q61R|HRAS_ENST00000311189.7_Missense_Mutation_p.Q61R	NM_176795.3	NP_789765.1	P01112	RASH_HUMAN	Harvey rat sarcoma viral oncogene homolog	61			Q -> K (in follicular thyroid carcinoma samples; somatic mutation; increases transformation of cultured cell lines; dbSNP:rs28933406).|Q -> L (in melanoma; strongly reduced GTP hydrolysis in the presence of RAF1; increases transformation of cultured cell lines).		activation of MAPKK activity|axon guidance|blood coagulation|cell cycle arrest|cellular senescence|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|mitotic cell cycle G1/S transition checkpoint|negative regulation of cell proliferation|nerve growth factor receptor signaling pathway|organ morphogenesis|positive regulation of DNA replication|positive regulation of epithelial cell proliferation|Ras protein signal transduction|synaptic transmission	cytosol|Golgi membrane|plasma membrane	GTP binding|GTPase activity|protein C-terminus binding	p.Q61R(136)|p.Q61L(117)|p.Q61P(3)		adrenal_gland(1)|bone(3)|breast(7)|cervix(23)|endometrium(4)|haematopoietic_and_lymphoid_tissue(12)|kidney(1)|large_intestine(2)|liver(1)|lung(16)|oesophagus(2)|penis(2)|pituitary(10)|prostate(31)|salivary_gland(24)|skin(184)|soft_tissue(38)|stomach(14)|testis(5)|thymus(1)|thyroid(173)|upper_aerodigestive_tract(122)|urinary_tract(225)	901		all_cancers(49;4.37e-09)|all_epithelial(84;2.09e-06)|Breast(177;0.000162)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.0538)|all_lung(207;0.0713)		all cancers(45;7.63e-28)|Epithelial(43;7.29e-27)|OV - Ovarian serous cystadenocarcinoma(40;7.15e-21)|BRCA - Breast invasive adenocarcinoma(625;3.56e-05)|Lung(200;0.0375)|LUSC - Lung squamous cell carcinoma(625;0.0703)	Sulindac(DB00605)	GTACTCCTCCTGGCCGGCGGT	0.597000	Q61L(KNS62_LUNG)|Q61L(KYSE30_OESOPHAGUS)|Q61L(NCIH1915_LUNG)	6	Mis		"""infrequent sarcomas, rare other types"""	"""rhadomyosarcoma, ganglioneuroblastoma, bladder"""			Costello syndrome	HNSCC(11;0.0054)			40	49					0	0	1	0	0
IGHV1OR16-3	28313	broad.mit.edu	37	16	32070612	32070612	+	RNA	SNP	A	A	C			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr16:32070612A>C	ENST00000566806.1	-	0	499																											GGTCTCCTGCAAGGCTTCTGG	0.552000													4	56					0	0	1	0	0
EPS8L2	64787	broad.mit.edu	37	11	721659	721659	+	Missense_Mutation	SNP	A	A	G			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr11:721659A>G	ENST00000533256.1	+	11	1238	c.863A>G	c.(862-864)aAg>aGg	p.K288R	EPS8L2_ENST00000526198.1_Missense_Mutation_p.K304R|EPS8L2_ENST00000530636.1_Missense_Mutation_p.K288R|EPS8L2_ENST00000318562.8_Missense_Mutation_p.K288R|AP006621.9_ENST00000527021.2_RNA			Q9H6S3	ES8L2_HUMAN	EPS8-like 2	288						cytoplasm				NS(1)|endometrium(1)|kidney(2)|large_intestine(2)|lung(2)|pancreas(1)|prostate(2)|soft_tissue(1)|urinary_tract(1)	13		all_cancers(49;1.24e-08)|all_epithelial(84;1.87e-05)|Breast(177;0.000286)|Ovarian(85;0.000953)|Medulloblastoma(188;0.0109)|all_neural(188;0.0299)|Lung NSC(207;0.106)|all_lung(207;0.136)		all cancers(45;4.37e-27)|Epithelial(43;2.81e-26)|OV - Ovarian serous cystadenocarcinoma(40;1.33e-20)|BRCA - Breast invasive adenocarcinoma(625;4.29e-05)|Lung(200;0.0582)|LUSC - Lung squamous cell carcinoma(625;0.0703)		CAGCGGAAAAAGGGGAAGAAG	0.657000													3	39					0	0	1	0	0
GOT1	2805	broad.mit.edu	37	10	101157431	101157431	+	Missense_Mutation	SNP	T	T	C			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr10:101157431T>C	ENST00000370508.5	-	9	1142	c.1115A>G	c.(1114-1116)gAg>gGg	p.E372G	GOT1_ENST00000543866.1_Missense_Mutation_p.E351G	NM_002079.2	NP_002070.1	P17174	AATC_HUMAN	glutamic-oxaloacetic transaminase 1, soluble	372					aspartate catabolic process|cellular response to insulin stimulus|gluconeogenesis|response to glucocorticoid stimulus	cytosol	L-aspartate:2-oxoglutarate aminotransferase activity|pyridoxal phosphate binding			endometrium(2)|kidney(1)|large_intestine(6)|lung(5)|prostate(2)	16		Ovarian(717;0.028)|Colorectal(252;0.234)		Epithelial(162;4.76e-10)|all cancers(201;3.84e-08)	L-Aspartic Acid(DB00128)|L-Cysteine(DB00151)|L-Glutamic Acid(DB00142)|Pyridoxal Phosphate(DB00114)	GACCAGATACTCAACCTGCTT	0.443000													4	52					0	0	1	0	0
ACIN1	22985	broad.mit.edu	37	14	23531643	23531643	+	Silent	SNP	T	T	C			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr14:23531643T>C	ENST00000262710.1	-	15	3474	c.3147A>G	c.(3145-3147)aaA>aaG	p.K1049K	ACIN1_ENST00000397341.3_Silent_p.K291K|ACIN1_ENST00000557515.1_Silent_p.K290K|ACIN1_ENST00000357481.2_Silent_p.K291K|ACIN1_ENST00000338631.6_Silent_p.K322K|ACIN1_ENST00000555053.1_Silent_p.K1036K|ACIN1_ENST00000457657.1_Silent_p.K1009K|ACIN1_ENST00000605057.1_Silent_p.K991K	NM_001164814.1|NM_014977.3	NP_001158286.1|NP_055792.1	Q9UKV3	ACINU_HUMAN	apoptotic chromatin condensation inducer 1	1049					apoptotic chromosome condensation|erythrocyte differentiation|positive regulation of monocyte differentiation	cytosol	ATPase activity|enzyme binding|nucleic acid binding|nucleotide binding			breast(1)|endometrium(6)|kidney(4)|large_intestine(9)|lung(10)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	37	all_cancers(95;1.36e-05)			GBM - Glioblastoma multiforme(265;0.00816)		AGCAATGAGATTTGATCTTGT	0.478000													91	148					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414343	20414343	+	Silent	SNP	A	A	G			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr9:20414343A>G	ENST00000380338.4	-	5	787	c.501T>C	c.(499-501)agT>agC	p.S167S	MLLT3_ENST00000429426.2_Silent_p.S164S|MLLT3_ENST00000355930.6_5'UTR|MLLT3_ENST00000475957.1_5'UTR	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	167	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S167S(19)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctgctactgctgctgc	0.532000			T	MLL	ALL								5	69					0	0	1	0	0
PCDH9	5101	broad.mit.edu	37	13	67802021	67802021	+	Silent	SNP	C	C	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr13:67802021C>T	ENST00000544246.1	-	2	1243	c.552G>A	c.(550-552)ggG>ggA	p.G184G	PCDH9_ENST00000377865.2_Silent_p.G184G|PCDH9_ENST00000377861.3_Silent_p.G184G|PCDH9_ENST00000328454.5_Silent_p.G184G|PCDH9_ENST00000456367.1_Silent_p.G184G	NM_203487.2	NP_982354.1	Q9HC56	PCDH9_HUMAN	protocadherin 9	184	Cadherin 2.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			breast(2)|central_nervous_system(3)|cervix(2)|endometrium(7)|kidney(4)|large_intestine(33)|lung(30)|ovary(5)|pancreas(2)|prostate(1)|skin(4)|stomach(2)|upper_aerodigestive_tract(5)|urinary_tract(3)	103		Hepatocellular(98;0.0906)|Breast(118;0.107)		GBM - Glioblastoma multiforme(99;0.00819)		AAACACTCTGCCCATTTAACA	0.428000													4	169					0	0	1	0	0
PRELP	5549	broad.mit.edu	37	1	203453039	203453039	+	Missense_Mutation	SNP	G	G	A			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr1:203453039G>A	ENST00000343110.2	+	2	854	c.727G>A	c.(727-729)Gcc>Acc	p.A243T		NM_002725.3|NM_201348.1	NP_002716.1|NP_958505.1	P51888	PRELP_HUMAN	proline/arginine-rich end leucine-rich repeat protein	243					skeletal system development	proteinaceous extracellular matrix	extracellular matrix structural constituent			breast(1)|central_nervous_system(1)|endometrium(4)|kidney(2)|large_intestine(7)|lung(15)|ovary(2)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	36			BRCA - Breast invasive adenocarcinoma(75;0.109)			GGTCCCCACCGCCATTCACCA	0.532000													45	111					0	0	1	0	0
MAGEC1	9947	broad.mit.edu	37	X	140994960	140994960	+	Silent	SNP	G	G	A			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chrX:140994960G>A	ENST00000285879.4	+	4	2056	c.1770G>A	c.(1768-1770)ctG>ctA	p.L590L	MAGEC1_ENST00000406005.2_Intron	NM_005462.4	NP_005453.2	O60732	MAGC1_HUMAN	melanoma antigen family C, 1	590							protein binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(8)|large_intestine(22)|lung(60)|ovary(1)|pancreas(1)|prostate(1)|skin(7)|stomach(5)|upper_aerodigestive_tract(7)|urinary_tract(1)	127	Acute lymphoblastic leukemia(192;6.56e-05)					AGGACTCCCTGTCTCCTCACT	0.567000										HNSCC(15;0.026)			6	438					0	0	1	0	0
PCLO	27445	broad.mit.edu	37	7	82784468	82784468	+	Missense_Mutation	SNP	C	C	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr7:82784468C>T	ENST00000423517.2	-	2	1826	c.1489G>A	c.(1489-1491)Gca>Aca	p.A497T	PCLO_ENST00000333891.8_Missense_Mutation_p.A497T	NM_014510.2	NP_055325.2	Q9Y6V0	PCLO_HUMAN	piccolo presynaptic cytomatrix protein	443	10 X 10 AA tandem approximate repeats of P-A-K-P-Q-P-Q-Q-P-X.|Gln-rich.|Pro-rich.				cytoskeleton organization|synaptic vesicle exocytosis	cell junction|cytoskeleton|synaptic vesicle	calcium ion binding|calcium-dependent phospholipid binding|profilin binding|transporter activity			breast(3)|central_nervous_system(3)|cervix(5)|endometrium(19)|haematopoietic_and_lymphoid_tissue(3)|kidney(19)|large_intestine(35)|lung(145)|ovary(7)|prostate(4)|upper_aerodigestive_tract(14)|urinary_tract(2)	259						GGGGGCTTTGCTGAGCCAGGC	0.612000													4	208					0	0	1	0	0
LOC644669	644669	broad.mit.edu	37	18	15323276	15323276	+	RNA	SNP	A	A	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr18:15323276A>T	ENST00000455308.2	-	0	572					NR_027417.1																						ATCAACTGCAATTGCATTTGC	0.308000													3	22					0	0	1	0	0
SPATA31C1	441452	broad.mit.edu	37	9	90535468	90535468	+	RNA	SNP	T	T	C			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr9:90535468T>C	ENST00000602681.1	+	0	1372																											ACCTGCACTTTTCCCTCACCC	0.612000													5	298					0	0	1	0	0
GLTSCR2	29997	broad.mit.edu	37	19	48255821	48255821	+	Missense_Mutation	SNP	C	C	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr19:48255821C>T	ENST00000246802.5	+	6	760	c.722C>T	c.(721-723)gCg>gTg	p.A241V	GLTSCR2_ENST00000598681.1_3'UTR	NM_015710.4	NP_056525.2	Q9NZM5	GSCR2_HUMAN	glioma tumor suppressor candidate region gene 2	241						nucleolus				central_nervous_system(1)|endometrium(2)|kidney(2)|large_intestine(3)|lung(5)|ovary(1)|prostate(1)	15		all_cancers(25;1.47e-06)|all_lung(116;6.89e-05)|all_epithelial(76;0.000108)|Lung NSC(112;0.000117)|all_neural(266;0.0332)|Ovarian(192;0.086)		all cancers(93;0.000301)|OV - Ovarian serous cystadenocarcinoma(262;0.00031)|Epithelial(262;0.0149)|GBM - Glioblastoma multiforme(486;0.0278)		GTGGAGGTGGCGCCTGCCGGA	0.667000													3	47					0	0	1	0	0
CHRM4	1132	broad.mit.edu	37	11	46408059	46408059	+	Missense_Mutation	SNP	G	G	A			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr11:46408059G>A	ENST00000433765.2	-	1	48	c.49C>T	c.(49-51)Cgc>Tgc	p.R17C		NM_000741.2	NP_000732.2	P08173	ACM4_HUMAN	cholinergic receptor, muscarinic 4	17					cell proliferation	cell junction|integral to plasma membrane|postsynaptic membrane	muscarinic acetylcholine receptor activity			breast(1)|endometrium(7)|kidney(1)|large_intestine(1)|lung(6)|prostate(3)|skin(1)	20				GBM - Glioblastoma multiforme(35;0.0254)|Lung(87;0.14)	Atropine(DB00572)|Benzquinamide(DB00767)|Cryptenamine(DB00785)|Homatropine Methylbromide(DB00725)|Methotrimeprazine(DB01403)|Metixene(DB00340)|Olanzapine(DB00334)|Procyclidine(DB00387)|Promazine(DB00420)|Promethazine(DB01069)|Propiomazine(DB00777)|Thiethylperazine(DB00372)|Tropicamide(DB00809)	GTGACCAGGCGCACGGACTGA	0.577000													4	127					0	0	1	0	0
GPRC5B	51704	broad.mit.edu	37	16	19873270	19873270	+	Silent	SNP	G	G	A	rs146737474	byFrequency	TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr16:19873270G>A	ENST00000300571.2	-	3	1247	c.1056C>T	c.(1054-1056)aaC>aaT	p.N352N	GPRC5B_ENST00000569847.1_Silent_p.N352N|GPRC5B_ENST00000569479.1_Silent_p.N352N|GPRC5B_ENST00000535671.1_Silent_p.N352N|GPRC5B_ENST00000537135.1_Silent_p.N378N	NM_016235.1	NP_057319.1	Q9NZH0	GPC5B_HUMAN	G protein-coupled receptor, family C, group 5, member B	352										breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(5)|lung(11)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	25						CCAAGCTGCCGTTGGGAAATC	0.517000													4	64					0	0	1	0	0
HMCES	56941	broad.mit.edu	37	3	129007830	129007830	+	Missense_Mutation	SNP	G	G	T	rs114856369	by1000genomes	TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr3:129007830G>T	ENST00000383463.4	+	3	406	c.317G>T	c.(316-318)cGg>cTg	p.R106L	C3orf37_ENST00000389735.3_Missense_Mutation_p.R106L|C3orf37_ENST00000417226.2_Missense_Mutation_p.R106L|C3orf37_ENST00000502878.2_Missense_Mutation_p.R106L	NM_020187.2	NP_064572.2	Q96FZ2	CC037_HUMAN		106										breast(1)|endometrium(1)|kidney(2)|lung(5)|ovary(1)|urinary_tract(4)	14						ATGGAGAAACGGTCATTTAAG	0.468000													3	46					0.115264	0.115264	1	1	0
PEX10	5192	broad.mit.edu	37	1	2340298	2340299	+	Splice_Site	INS	-	-	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr1:2340298_2340299insT	ENST00000288774.3	-	3	221		c.e3-1		PEX10_ENST00000515760.1_Splice_Site|PEX10_ENST00000507596.1_Splice_Site|PEX10_ENST00000447513.2_Splice_Site	NM_153818.1	NP_722540.1	O60683	PEX10_HUMAN	peroxisomal biogenesis factor 10						protein import into peroxisome matrix	integral to peroxisomal membrane|peroxisomal membrane	protein binding|protein C-terminus binding|zinc ion binding			central_nervous_system(1)|haematopoietic_and_lymphoid_tissue(1)|lung(3)|skin(2)	7	all_cancers(77;0.000247)|all_epithelial(69;9.96e-05)|all_lung(157;0.016)|Lung NSC(156;0.0376)|Ovarian(185;0.0634)	all_epithelial(116;5.35e-20)|all_lung(118;2.78e-08)|Lung NSC(185;2.69e-06)|Breast(487;0.00147)|Renal(390;0.00183)|Hepatocellular(190;0.00826)|Myeloproliferative disorder(586;0.0122)|Ovarian(437;0.0308)|Medulloblastoma(700;0.123)|Lung SC(97;0.128)		Epithelial(90;1.1e-37)|OV - Ovarian serous cystadenocarcinoma(86;6.02e-23)|GBM - Glioblastoma multiforme(42;9e-08)|Colorectal(212;3.94e-05)|COAD - Colon adenocarcinoma(227;0.000193)|Kidney(185;0.00102)|BRCA - Breast invasive adenocarcinoma(365;0.00435)|STAD - Stomach adenocarcinoma(132;0.00644)|KIRC - Kidney renal clear cell carcinoma(229;0.0169)|Lung(427;0.199)		GTCTGGTAGCCTGCGAGGAAGA	0.663													14	5	---	---	---	---					
LINC00570	100874055	broad.mit.edu	37	2	11542812	11542814	+	RNA	DEL	CCA	CCA	-			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr2:11542812_11542814delCCA	ENST00000417473.2	+	0	939_941					NR_047499.1																						gccatcaccgccaccaccaccac	0.586													4	6	---	---	---	---					
IGHV4-61	28391	broad.mit.edu	37	14	107095573	107095573	+	RNA	DEL	G	G	-			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr14:107095573delG	ENST00000390630.2	-	0	89																											TTCTTGCACAGGAGGTCCAGG	0.507													9	60	---	---	---	---					
ULK4P3	89837	broad.mit.edu	37	15	30406088	30406089	+	RNA	INS	-	-	T			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr15:30406088_30406089insT	ENST00000568486.1	+	0	402					NR_026859.1																						TGCCTCAAAAGTTTTTTTTTTT	0.297													7	20	---	---	---	---					
LOC101927755	101927755	broad.mit.edu	37	17	58066608	58066608	+	RNA	DEL	T	T	-			TCGA-SR-A6MY-01A-11D-A35I-08	TCGA-SR-A6MY-10A-01D-A35G-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	5eef7f6e-b52f-45d4-9482-4b3f926d8bbb	fa3d968f-2b1c-4658-b96b-36ee5a79b860	g.chr17:58066608delT	ENST00000586209.1	+	0	158																											TTGATTGTGATTTTTTTTTTT	0.313													4	5	---	---	---	---