Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
CRELD2	79174	broad.mit.edu	37	22	50316920	50316920	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr22:50316920G>A	ENST00000404488.3	+	8	1009	c.874G>A	c.(874-876)Gct>Act	p.A292T	CRELD2_ENST00000403427.3_Intron|CRELD2_ENST00000407217.3_Missense_Mutation_p.A243T|CRELD2_ENST00000444954.1_3'UTR|CRELD2_ENST00000328268.4_Missense_Mutation_p.A243T	NM_001135101.1	NP_001128573.1	Q6UXH1	CREL2_HUMAN	cysteine-rich with EGF-like domains 2	243	EGF-like 2; calcium-binding (Potential).					endoplasmic reticulum|extracellular region	calcium ion binding			endometrium(1)|large_intestine(1)|lung(3)|ovary(1)|stomach(3)	9		all_cancers(38;5.53e-07)|all_epithelial(38;3.84e-06)|all_lung(38;0.00208)|Breast(42;0.0104)|Lung NSC(38;0.0199)|Ovarian(80;0.0907)|Lung SC(80;0.236)		BRCA - Breast invasive adenocarcinoma(115;0.198)|LUAD - Lung adenocarcinoma(64;0.247)		TCCCTGCAGCGCTGCGCAGTT	0.692000													14	26					0	0	1	0	0
PRKD2	25865	broad.mit.edu	37	19	47197153	47197153	+	Missense_Mutation	SNP	C	C	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr19:47197153C>A	ENST00000433867.1	-	11	2032	c.1555G>T	c.(1555-1557)Gcc>Tcc	p.A519S	PRKD2_ENST00000595515.1_Missense_Mutation_p.A519S|PRKD2_ENST00000600194.1_Missense_Mutation_p.A362S|PRKD2_ENST00000291281.4_Missense_Mutation_p.A519S|PRKD2_ENST00000601806.1_Missense_Mutation_p.A362S	NM_001079880.1|NM_001079881.1|NM_016457.4	NP_001073349.1|NP_001073350.1|NP_057541.2	Q9BZL6	KPCD2_HUMAN	protein kinase D2	519					cell death|intracellular signal transduction|positive regulation of transcription from RNA polymerase II promoter|protein autophosphorylation|T cell receptor signaling pathway	cytoplasm|membrane|nucleus	ATP binding|metal ion binding|protein kinase C activity			central_nervous_system(3)|endometrium(4)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(9)|lung(13)|ovary(2)|prostate(2)|skin(1)|stomach(2)|urinary_tract(1)	41		Ovarian(192;0.0129)|all_neural(266;0.0459)|Breast(70;0.212)		OV - Ovarian serous cystadenocarcinoma(262;0.000189)|all cancers(93;0.000545)|Epithelial(262;0.0219)|GBM - Glioblastoma multiforme(486;0.0353)		TGGCCTGGGGCGCTGGGTGCG	0.672000													13	44					7.93312e-07	8.96788e-07	1	1	0
TTI1	9675	broad.mit.edu	37	20	36640810	36640810	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr20:36640810C>T	ENST00000373448.2	-	3	1647	c.1409G>A	c.(1408-1410)cGc>cAc	p.R470H	TTI1_ENST00000487362.1_5'UTR|TTI1_ENST00000373447.3_Missense_Mutation_p.R470H|TTI1_ENST00000449821.1_Missense_Mutation_p.R470H	NM_014657.1	NP_055472.1	O43156	TTI1_HUMAN	TELO2 interacting protein 1	470							binding			breast(3)|central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(6)|liver(1)|lung(18)|ovary(3)|pancreas(1)|prostate(3)|skin(3)	47						CCTCTGGATGCGGTTCCAAGG	0.463000													3	63					0	0	1	0	0
SORCS3	22986	broad.mit.edu	37	10	106982994	106982994	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr10:106982994G>A	ENST00000369701.3	+	20	3082	c.2855G>A	c.(2854-2856)gGc>gAc	p.G952D	SORCS3_ENST00000369699.4_3'UTR	NM_014978.1	NP_055793.1	Q9UPU3	SORC3_HUMAN	sortilin-related VPS10 domain containing receptor 3	952						integral to membrane	neuropeptide receptor activity			autonomic_ganglia(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(19)|lung(63)|ovary(6)|pancreas(1)|prostate(6)|skin(8)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(2)	131		Colorectal(252;0.134)|Breast(234;0.142)|Lung NSC(174;0.191)		Epithelial(162;1.58e-07)|all cancers(201;1.02e-05)|BRCA - Breast invasive adenocarcinoma(275;0.0628)		TGGTGGTTCGGCAATAGCACA	0.458000													5	196					0	0	1	0	0
TUBB8P7	197331	broad.mit.edu	37	16	90162513	90162513	+	RNA	SNP	T	T	C			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr16:90162513T>C	ENST00000567960.1	+	0	1249				TUBB8P7_ENST00000564451.1_RNA														p.N415N(2)									GCAACATGAATGACCTGGTGT	0.537000													4	140					0	0	1	0	0
NRSN2	80023	broad.mit.edu	37	20	333947	333947	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr20:333947G>A	ENST00000382291.3	+	4	523	c.283G>A	c.(283-285)Gag>Aag	p.E95K	NRSN2_ENST00000382285.2_Missense_Mutation_p.E95K|NRSN2_ENST00000492242.1_3'UTR	NM_024958.2	NP_079234.1	Q9GZP1	NRSN2_HUMAN	neurensin 2	95						integral to membrane|plasma membrane|transport vesicle				endometrium(1)|large_intestine(2)|lung(4)|urinary_tract(1)	8		all_cancers(10;0.0834)				GGGCATCGGTGAGGGTGAGTT	0.652000													4	78					0	0	1	0	0
SNHG14	104472715	broad.mit.edu	37	15	25467500	25467500	+	RNA	SNP	G	G	C			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr15:25467500G>C	ENST00000453082.2	+	0	753				SNORD115-28_ENST00000363931.1_RNA	NR_003343.1																						GGTTGGGGTGGTGATGAGAAC	0.522000													84	195					0	0	1	0	0
FOXD4	2298	broad.mit.edu	37	9	117692	117692	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr9:117692C>T	ENST00000382500.2	-	1	725	c.428G>A	c.(427-429)cGc>cAc	p.R143H		NM_207305.4	NP_997188.2	Q12950	FOXD4_HUMAN	forkhead box D4	143					axon extension involved in axon guidance|cartilage development|dichotomous subdivision of terminal units involved in ureteric bud branching|embryo development|enteric nervous system development|iridophore differentiation|lateral line nerve glial cell development|melanocyte differentiation|neural crest cell migration|pattern specification process|peripheral nervous system development|positive regulation of BMP signaling pathway|positive regulation of kidney development|positive regulation of transcription from RNA polymerase II promoter|regulation of sequence-specific DNA binding transcription factor activity|sympathetic nervous system development	transcription factor complex	DNA bending activity|double-stranded DNA binding|promoter binding|sequence-specific DNA binding|sequence-specific enhancer binding RNA polymerase II transcription factor activity|specific RNA polymerase II transcription factor activity|specific transcriptional repressor activity|transcription activator activity|transcription factor binding			endometrium(5)|large_intestine(2)|lung(3)|prostate(1)|skin(3)	14	all_lung(41;0.218)	all_cancers(5;0.0395)|Acute lymphoblastic leukemia(5;1.91e-07)|all_hematologic(5;1.95e-06)	Kidney(42;0.112)|KIRC - Kidney renal clear cell carcinoma(5;0.157)	all cancers(5;0.000704)|Lung(218;0.00755)|GBM - Glioblastoma multiforme(5;0.0149)|Epithelial(6;0.0154)		GGGGAACTTGCGGCGGTAGTA	0.642000													6	371					0	0	1	0	0
SUN1	23353	broad.mit.edu	37	7	882981	882981	+	Missense_Mutation	SNP	G	G	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr7:882981G>T	ENST00000456758.2	+	8	656	c.656G>T	c.(655-657)gGa>gTa	p.G219V	SUN1_ENST00000457378.2_Missense_Mutation_p.G182V|SUN1_ENST00000452783.2_Intron|SUN1_ENST00000401592.1_Missense_Mutation_p.G161V|SUN1_ENST00000425407.2_Missense_Mutation_p.G111V|SUN1_ENST00000389574.3_Missense_Mutation_p.G111V|SUN1_ENST00000405266.1_Missense_Mutation_p.G161V|SUN1_ENST00000403868.1_Missense_Mutation_p.G161V			O94901	SUN1_HUMAN	Sad1 and UNC84 domain containing 1	161	SYNE2-binding.				cytoskeletal anchoring at nuclear membrane|nuclear matrix anchoring at nuclear membrane	integral to membrane|nuclear inner membrane|SUN-KASH complex	protein binding			NS(1)|endometrium(1)|kidney(2)|large_intestine(7)|lung(17)|upper_aerodigestive_tract(1)|urinary_tract(1)	30						ACTTTAGGTGGAAATAAAGCT	0.468000													11	133					3.07112e-06	3.32704e-06	1	1	0
WDR63	126820	broad.mit.edu	37	1	85547042	85547042	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr1:85547042G>A	ENST00000294664.6	+	4	409	c.229G>A	c.(229-231)Gac>Aac	p.D77N	WDR63_ENST00000370596.1_Missense_Mutation_p.D77N|WDR63_ENST00000326813.8_Missense_Mutation_p.D77N	NM_145172.3	NP_660155.2	Q8IWG1	WDR63_HUMAN	WD repeat domain 63	77										NS(1)|breast(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(7)|lung(13)|ovary(2)|skin(2)|upper_aerodigestive_tract(3)	36				all cancers(265;0.00391)|Epithelial(280;0.00922)|Colorectal(170;0.166)		CATTTTTGAGGACCTGCGCAA	0.378000													21	34					0	0	1	0	0
MLLT3	4300	broad.mit.edu	37	9	20414346	20414346	+	Silent	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr9:20414346G>A	ENST00000380338.4	-	5	784	c.498C>T	c.(496-498)agC>agT	p.S166S	MLLT3_ENST00000475957.1_5'UTR|MLLT3_ENST00000355930.6_5'UTR|MLLT3_ENST00000429426.2_Silent_p.S163S	NM_004529.2	NP_004520.2	P42568	AF9_HUMAN	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	166	Poly-Ser.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	protein binding	p.S166S(4)		central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(6)|lung(24)|ovary(1)|prostate(4)|skin(1)|urinary_tract(7)	66				GBM - Glioblastoma multiforme(3;4.35e-105)|Lung(42;3.48e-06)|LUSC - Lung squamous cell carcinoma(42;7.92e-05)		tgctgctactgctgctgctgc	0.527000			T	MLL	ALL								4	70					0	0	1	0	0
MGAM	8972	broad.mit.edu	37	7	141708443	141708443	+	Nonsense_Mutation	SNP	G	G	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr7:141708443G>T	ENST00000475668.2	+	3	319	c.265G>T	c.(265-267)Gaa>Taa	p.E89*	MGAM_ENST00000549489.2_Nonsense_Mutation_p.E89*			O43451	MGA_HUMAN	maltase-glucoamylase (alpha-glucosidase)	89	P-type 1.				polysaccharide digestion|starch catabolic process	apical plasma membrane|integral to membrane	carbohydrate binding|glucan 1,4-alpha-glucosidase activity|maltose alpha-glucosidase activity			cervix(1)|endometrium(1)|large_intestine(4)|lung(3)|ovary(2)|skin(2)	13	Melanoma(164;0.0272)				Acarbose(DB00284)|Miglitol(DB00491)|Voglibose(DB04878)	TGTTTCTGCTGAATGTCCAGT	0.448000													7	54					2.52707e-12	2.98654e-12	1	1	0
ODAM	54959	broad.mit.edu	37	4	71062416	71062416	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr4:71062416C>G	ENST00000396094.2	+	2	107	c.59C>G	c.(58-60)cCa>cGa	p.P20R		NM_017855.3	NP_060325.3	A1E959	ODAM_HUMAN	odontogenic, ameloblast asssociated	20					biomineral tissue development|odontogenesis of dentine-containing tooth	fibril				NS(1)|breast(2)|endometrium(2)|large_intestine(2)|lung(8)|ovary(3)|skin(2)	20						TAGCTTATCCCACAGCGTCTC	0.333000													9	85					0	0	1	0	0
FAM86JP	100125556	broad.mit.edu	37	3	125647387	125647387	+	RNA	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr3:125647387G>A	ENST00000485843.1	+	0	532					NR_024251.1																						ACCAGAAACTGTTTCCCTATG	0.502000													5	152					0	0	1	0	0
DNM1P47	100216544	broad.mit.edu	37	15	102304896	102304896	+	RNA	SNP	C	C	G	rs145942024	by1000genomes	TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr15:102304896C>G	ENST00000561463.1	+	0	12942																											GAAGACACTCCTGGAGGAGTC	0.562000													3	26					0	0	1	0	0
NBEAL2	23218	broad.mit.edu	37	3	47041446	47041446	+	Translation_Start_Site	SNP	A	A	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr3:47041446A>T	ENST00000383740.2	+	0	4036				NBEAL2_ENST00000292309.5_Intron|NBEAL2_ENST00000450053.3_Missense_Mutation_p.D1286V			Q6ZNJ1	NBEL2_HUMAN	neurobeachin-like 2								binding			NS(1)|breast(1)|central_nervous_system(3)|cervix(2)|endometrium(8)|kidney(5)|large_intestine(9)|lung(9)|ovary(4)|pancreas(1)|prostate(3)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	51		Acute lymphoblastic leukemia(5;0.0534)		BRCA - Breast invasive adenocarcinoma(193;0.0012)|KIRC - Kidney renal clear cell carcinoma(197;0.00575)|Kidney(197;0.00656)		GGCTGGCAAGATGTGCTGACC	0.632000													10	30					0	0	1	0	0
TRBV6-5	28602	broad.mit.edu	37	7	142180979	142180979	+	RNA	SNP	C	C	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr7:142180979C>T	ENST00000390368.2	-	0	37																											GAGGGGTCTTCTGTATCTGTG	0.602000													4	40					0	0	1	0	0
SIGLEC16	400709	broad.mit.edu	37	19	50473221	50473221	+	RNA	SNP	T	T	C	rs117072442	by1000genomes	TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr19:50473221T>C	ENST00000602139.1	+	0	222									sialic acid binding Ig-like lectin 16 (gene/pseudogene)									p.W65R(3)		endometrium(2)|kidney(2)|lung(6)	10						GTTCAAAGGATGGACCAGCCC	0.602000													6	27					0	0	1	0	0
HEPN1	641654	broad.mit.edu	37	11	124789688	124789688	+	Silent	SNP	C	C	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr11:124789688C>T	ENST00000408930.5	+	1	543	c.42C>T	c.(40-42)ggC>ggT	p.G14G	HEPACAM_ENST00000298251.4_3'UTR	NM_001037558.2	NP_001032647.2	Q6WQI6	HEPN1_HUMAN	hepatocellular carcinoma, down-regulated 1	14						cytoplasm				large_intestine(1)|lung(1)|stomach(1)	3	all_hematologic(175;0.215)	Medulloblastoma(222;0.0523)|Lung NSC(97;0.118)|all_lung(97;0.126)|Breast(109;0.171)|all_neural(223;0.224)		BRCA - Breast invasive adenocarcinoma(274;1.49e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.0287)		GGGTTGATGGCGAATCAGAGC	0.512000													8	45					0	0	1	0	0
FAM86JP	100125556	broad.mit.edu	37	3	125647396	125647396	+	RNA	SNP	T	T	C			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr3:125647396T>C	ENST00000485843.1	+	0	541					NR_024251.1																						TGTTTCCCTATGAAGAGCACT	0.502000													6	154					0	0	1	0	0
ING3	54556	broad.mit.edu	37	7	120607662	120607662	+	Silent	SNP	A	A	G			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr7:120607662A>G	ENST00000315870.5	+	7	664	c.516A>G	c.(514-516)ctA>ctG	p.L172L	ING3_ENST00000431467.1_Silent_p.L157L	NM_019071.2	NP_061944.2	Q9NXR8	ING3_HUMAN	inhibitor of growth family, member 3	172					histone H2A acetylation|histone H4 acetylation|positive regulation of apoptosis|regulation of growth|regulation of transcription, DNA-dependent|transcription, DNA-dependent	NuA4 histone acetyltransferase complex|Piccolo NuA4 histone acetyltransferase complex	zinc ion binding			NS(1)|large_intestine(2)|lung(7)|ovary(1)|urinary_tract(1)	12	all_neural(327;0.117)					AAGCTCTTCTATCCACCCTTA	0.303000													51	146					0	0	1	0	0
LDLRAD2	401944	broad.mit.edu	37	1	22142457	22142457	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr1:22142457G>A	ENST00000344642.2	+	3	720	c.533G>A	c.(532-534)cGc>cAc	p.R178H	LDLRAD2_ENST00000543870.1_Missense_Mutation_p.R178H	NM_001013693.2	NP_001013715.2	Q5SZI1	LRAD2_HUMAN	low density lipoprotein receptor class A domain containing 2	178	LDL-receptor class A.					integral to membrane	receptor activity			endometrium(2)|large_intestine(1)|lung(3)	6		Colorectal(325;0.000147)|Renal(390;0.000734)|Lung NSC(340;0.00166)|all_lung(284;0.00172)|Breast(348;0.012)|Myeloproliferative disorder(586;0.0393)|Ovarian(437;0.0427)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0416)|OV - Ovarian serous cystadenocarcinoma(117;5.2e-26)|COAD - Colon adenocarcinoma(152;1.13e-05)|GBM - Glioblastoma multiforme(114;1.36e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000544)|KIRC - Kidney renal clear cell carcinoma(1967;0.00598)|STAD - Stomach adenocarcinoma(196;0.00644)|READ - Rectum adenocarcinoma(331;0.0649)|Lung(427;0.197)		GCCTACTTCCGCTGCCAGAAT	0.622000													4	44					0	0	1	0	0
ZNF773	374928	broad.mit.edu	37	19	58016080	58016080	+	Missense_Mutation	SNP	G	G	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr19:58016080G>T	ENST00000599847.1	+	2	231	c.89G>T	c.(88-90)aGa>aTa	p.R30I	ZNF773_ENST00000282292.4_Missense_Mutation_p.R30I|AC003005.4_ENST00000601674.1_3'UTR|ZNF773_ENST00000593916.1_Missense_Mutation_p.R29I|ZNF773_ENST00000598770.1_Missense_Mutation_p.R29I			Q6PK81	ZN773_HUMAN	zinc finger protein 773	30	KRAB.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(6)|ovary(1)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	22		Colorectal(82;0.000256)|all_neural(62;0.0577)|Ovarian(87;0.221)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0254)		GAGGAATGGAGATTGCTTGAT	0.532000													5	125					0.184627	0.184627	1	1	0
OR7E62P	26479	broad.mit.edu	37	2	71283122	71283123	+	RNA	INS	-	-	T	rs35074164		TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr2:71283122_71283123insT	ENST00000434990.1	-	0	61																											GGCACCACCCCCAGGAGTGGTG	0.530													7	4	---	---	---	---					
PRKDC	5591	broad.mit.edu	37	8	48866909	48866910	+	Frame_Shift_Ins	INS	-	-	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr8:48866909_48866910insT	ENST00000314191.2	-	5	552_553	c.496_497insA	c.(496-498)accfs	p.T166fs	PRKDC_ENST00000338368.3_Frame_Shift_Ins_p.T166fs|PRKDC_ENST00000523565.1_5'UTR	NM_006904.6	NP_008835.5	P78527	PRKDC_HUMAN	protein kinase, DNA-activated, catalytic polypeptide	166					cellular response to insulin stimulus|double-strand break repair via nonhomologous end joining|peptidyl-serine phosphorylation|positive regulation of transcription from RNA polymerase II promoter	DNA-dependent protein kinase-DNA ligase 4 complex|transcription factor complex	ATP binding|DNA binding|DNA-dependent protein kinase activity|transcription factor binding			NS(1)|autonomic_ganglia(1)|breast(2)|central_nervous_system(9)|cervix(3)|endometrium(15)|haematopoietic_and_lymphoid_tissue(2)|kidney(6)|large_intestine(30)|lung(56)|ovary(6)|pancreas(1)|prostate(8)|skin(7)	147		all_cancers(86;0.0336)|all_epithelial(80;0.00111)|Lung NSC(129;0.00363)|all_lung(136;0.00391)				TGTATCTGGTATTTTTTTTTTC	0.267								Non-homologous end-joining					2	4	---	---	---	---					
BHLHE22	27319	broad.mit.edu	37	8	65493617	65493618	+	In_Frame_Ins	INS	-	-	GGC			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr8:65493617_65493618insGGC	ENST00000321870.1	+	1	804_805	c.270_271insGGC	c.(268-273)aggcgg>agGGCgcgg	p.90_91RR>RAR	RP11-21C4.1_ENST00000517909.1_RNA	NM_152414.4	NP_689627.1	Q8NFJ8	BHE22_HUMAN	basic helix-loop-helix family, member e22	90	Gly-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus				NS(1)|central_nervous_system(1)|lung(1)|prostate(1)|skin(1)	5						gcgcgggaagtggcggcggcgg	0.782													2	4	---	---	---	---					
TRAV9-1	28678	broad.mit.edu	37	14	22279845	22279846	+	RNA	INS	-	-	T			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr14:22279845_22279846insT	ENST00000390431.3	+	0	46																											TAATTTGTTTATTTTTTTTTCA	0.406													4	8	---	---	---	---					
SREBF1	6720	broad.mit.edu	37	17	17720609	17720609	+	Frame_Shift_Del	DEL	G	G	-			TCGA-QR-A70R-01A-11D-A35D-08	TCGA-QR-A70R-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	bf81a264-33bd-46bd-b03c-7c4537ee09e5	98d97958-f30c-438c-8f84-9d556fce7477	g.chr17:17720609delG	ENST00000355815.4	-	9	1826	c.1657delC	c.(1657-1659)atfs	p.H553fs	SREBF1_ENST00000338854.5_Frame_Shift_Del_p.H523fs|SREBF1_ENST00000395757.1_Frame_Shift_Del_p.H269fs|SREBF1_ENST00000261646.5_Frame_Shift_Del_p.H523fs	NM_001005291.2	NP_001005291.1	P36956	SRBP1_HUMAN	sterol regulatory element binding transcription factor 1	523					cellular response to starvation|cholesterol metabolic process|positive regulation of transcription from RNA polymerase II promoter|regulation of transcription from RNA polymerase II promoter	endoplasmic reticulum|endoplasmic reticulum membrane|ER to Golgi transport vesicle membrane|Golgi membrane|integral to membrane|nuclear envelope|nucleus	protein binding|sequence-specific DNA binding transcription factor activity|sterol response element binding			cervix(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(2)|lung(5)|skin(1)|urinary_tract(1)	14						CCAGGGCTATGGTAGACGCTG	0.677													3	3	---	---	---	---