Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
ITPR2	3709	broad.mit.edu	37	12	26628350	26628350	+	Splice_Site	SNP	A	A	C			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr12:26628350A>C	ENST00000381340.3	-	45	6637	c.6219_splice	c.e45-1	p.V2074_splice		NM_002223.2	NP_002214.2	Q14571	ITPR2_HUMAN	inositol 1,4,5-trisphosphate receptor, type 2	2074					activation of phospholipase C activity|energy reserve metabolic process|nerve growth factor receptor signaling pathway|platelet activation|regulation of insulin secretion|response to hypoxia	integral to membrane|plasma membrane enriched fraction|platelet dense tubular network membrane|sarcoplasmic reticulum membrane	calcium ion transmembrane transporter activity|inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity		ETV6/ITPR2(2)	biliary_tract(1)|breast(3)|central_nervous_system(1)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(2)|kidney(16)|large_intestine(20)|liver(1)|lung(51)|ovary(5)|pancreas(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(5)|urinary_tract(3)	125	Colorectal(261;0.0847)					CATCACATCCACCTATCCAAA	0.358000													6	37					0	0	1	0	0
ZBTB45	84878	broad.mit.edu	37	19	59028621	59028621	+	Silent	SNP	C	C	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:59028621C>G	ENST00000594051.1	-	2	900	c.420G>C	c.(418-420)gtG>gtC	p.V140V	ZBTB45_ENST00000600990.1_Silent_p.V140V|ZBTB45_ENST00000354590.3_Silent_p.V140V			Q96K62	ZBT45_HUMAN	zinc finger and BTB domain containing 45	140	Pro-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(2)|endometrium(3)|lung(5)|urinary_tract(1)	11		all_cancers(17;1.81e-17)|all_epithelial(17;1.21e-12)|Lung NSC(17;2.8e-05)|all_lung(17;0.000139)|Colorectal(82;0.000147)|Renal(17;0.00528)|all_neural(62;0.0133)|Ovarian(87;0.156)|Medulloblastoma(540;0.232)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0165)|Lung(386;0.18)		GTGGCGGGGGCACAGGGGTGG	0.701000											OREG0025700	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	5	13					0	0	1	0	0
TPTE2P6	374491	broad.mit.edu	37	13	25161397	25161397	+	RNA	SNP	C	C	G	rs3874227	by1000genomes	TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr13:25161397C>G	ENST00000453498.1	+	0	921																											TGAAACATCTCTACAACTGGA	0.343000													3	67					0	0	1	0	0
ZNF419	79744	broad.mit.edu	37	19	58004913	58004913	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:58004913C>G	ENST00000424930.2	+	5	1220	c.991C>G	c.(991-993)Ctc>Gtc	p.L331V	ZNF419_ENST00000415379.2_Missense_Mutation_p.L284V|ZNF419_ENST00000347466.6_Missense_Mutation_p.L298V|ZNF419_ENST00000442920.2_Missense_Mutation_p.L317V|AC003005.4_ENST00000601674.1_Intron|ZNF419_ENST00000354197.4_Missense_Mutation_p.L318V|ZNF419_ENST00000221735.7_Missense_Mutation_p.L330V|ZNF419_ENST00000426954.2_Missense_Mutation_p.L318V	NM_001098491.1|NM_024691.3	NP_001091961.1|NP_078967.3	Q96HQ0	ZN419_HUMAN	zinc finger protein 419	330					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(8)|lung(10)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	26		Colorectal(82;5.46e-05)|all_neural(62;0.0218)|Ovarian(87;0.0694)|Breast(46;0.0848)|Renal(1328;0.157)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0252)|Lung(386;0.171)		CAACTCCAGCCTCATGAAACA	0.408000													30	26					0	0	1	0	0
PRB4	5545	broad.mit.edu	37	12	11461589	11461589	+	Missense_Mutation	SNP	A	A	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr12:11461589A>G	ENST00000279575.1	-	3	361	c.328T>C	c.(328-330)Tcc>Ccc	p.S110P	PRB4_ENST00000445719.2_Missense_Mutation_p.S110P|PRB4_ENST00000535904.1_Missense_Mutation_p.S110P	NM_001261399.1|NM_002723.4	NP_001248328.1|NP_002714.2	P10163	PRB4_HUMAN	proline-rich protein BstNI subfamily 4	152	9.5 X 21 AA tandem repeats of K-P-[EQ]- [GR]-[PR]-[PR]-P-Q-G-G-N-Q-[PS]-[QH]- [RG]-[PT]-P-P-[PH]-P-G.					extracellular region				breast(2)|endometrium(2)|kidney(2)|large_intestine(4)|lung(12)|ovary(1)|skin(4)|upper_aerodigestive_tract(3)	30						GTACCTTGGGACTGGTTTCCT	0.602000										HNSCC(22;0.051)			6	213					0	0	1	0	0
ANKRD36C	400986	broad.mit.edu	37	2	96593016	96593016	+	Missense_Mutation	SNP	C	C	A	rs79307257	by1000genomes	TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr2:96593016C>A	ENST00000456556.1	-	28	1969	c.1885G>T	c.(1885-1887)Gat>Tat	p.D629Y						ankyrin repeat domain 36C									p.D629Y(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						GAAACAGAATCTTTCTCATCA	0.318000													4	65					0.014758	0.014758	1	1	0
NUP107	57122	broad.mit.edu	37	12	69115645	69115645	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr12:69115645G>A	ENST00000229179.4	+	16	1668	c.1336G>A	c.(1336-1338)Gaa>Aaa	p.E446K	NUP107_ENST00000378905.2_Missense_Mutation_p.E295K|NUP107_ENST00000539906.1_Missense_Mutation_p.E417K	NM_020401.2	NP_065134.1	P57740	NU107_HUMAN	nucleoporin 107kDa	446					carbohydrate metabolic process|glucose transport|mitotic prometaphase|mRNA export from nucleus|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	condensed chromosome kinetochore|cytosol|Nup107-160 complex	nucleocytoplasmic transporter activity|protein binding		NUP107/LGR5(2)	breast(3)|endometrium(4)|kidney(4)|large_intestine(12)|lung(11)|prostate(1)|skin(2)|urinary_tract(2)	39	Breast(13;6.25e-06)		Lung(24;0.000131)|LUAD - Lung adenocarcinoma(15;0.00107)|STAD - Stomach adenocarcinoma(21;0.00694)			TGACACCTGGGAAGACACAGT	0.438000													4	81					0	0	1	0	0
KIAA0247	9766	broad.mit.edu	37	14	70170160	70170160	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr14:70170160C>T	ENST00000342745.4	+	3	483	c.170C>T	c.(169-171)cCc>cTc	p.P57L		NM_014734.3	NP_055549.1	Q92537	K0247_HUMAN	KIAA0247	57	Sushi.					integral to membrane				endometrium(1)|kidney(1)|lung(4)|ovary(3)|upper_aerodigestive_tract(1)	10				all cancers(60;0.00155)|BRCA - Breast invasive adenocarcinoma(234;0.0164)|OV - Ovarian serous cystadenocarcinoma(108;0.0196)		ATCTGCCACCCCCGGCCCTGC	0.567000													18	66					0	0	1	0	0
LEFTY1	10637	broad.mit.edu	37	1	226076584	226076584	+	Silent	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr1:226076584G>A	ENST00000272134.5	-	1	262	c.183C>T	c.(181-183)taC>taT	p.Y61Y	RP4-559A3.7_ENST00000432920.2_Intron|LEFTY1_ENST00000492457.1_Intron	NM_020997.3	NP_066277.1	O75610	LFTY1_HUMAN	left-right determination factor 1	61					cell growth|multicellular organismal development|transforming growth factor beta receptor signaling pathway	extracellular space	cytokine activity|growth factor activity|transforming growth factor beta receptor binding			cervix(1)|endometrium(1)|large_intestine(1)|lung(4)|ovary(1)|skin(1)|upper_aerodigestive_tract(1)	10	Breast(184;0.197)					GCAGGGCCACGTACTGGGCCC	0.697000													7	16					0	0	1	0	0
HNRNPH1	3187	broad.mit.edu	37	5	179044053	179044053	+	Splice_Site	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr5:179044053G>A	ENST00000356731.5	-	9	2651	c.1117_splice	c.e9+1	p.Y372_splice	HNRNPH1_ENST00000442819.2_Splice_Site_p.Y372_splice|HNRNPH1_ENST00000329433.6_Splice_Site_p.Y372_splice|HNRNPH1_ENST00000511300.2_Silent_p.Y102Y|HNRNPH1_ENST00000510411.1_Silent_p.Y372Y|HNRNPH1_ENST00000393432.4_Splice_Site_p.Y372_splice			P31943	HNRH1_HUMAN	heterogeneous nuclear ribonucleoprotein H1 (H)	372	2 X 16 AA Gly-rich approximate repeats.|2 X 19 AA perfect repeats.				regulation of RNA splicing	actin cytoskeleton|catalytic step 2 spliceosome|cytoplasm|heterogeneous nuclear ribonucleoprotein complex|nucleoplasm	nucleotide binding|poly(U) RNA binding|protein binding			breast(1)|cervix(1)|endometrium(2)|kidney(3)|large_intestine(2)|lung(4)|skin(1)	14						TTTGGCTACCGTAAGCACCAC	0.373000													4	101					0	0	1	0	0
CEACAM5	1048	broad.mit.edu	37	19	42213811	42213811	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:42213811C>T	ENST00000221992.6	+	2	391	c.277C>T	c.(277-279)Ccc>Tcc	p.P93S	CEACAM5_ENST00000405816.1_Missense_Mutation_p.P93S|CEA_ENST00000598976.1_Missense_Mutation_p.P93S|CEACAM5_ENST00000398599.4_Missense_Mutation_p.P93S	NM_004363.2	NP_004354.2	P06731	CEAM5_HUMAN	carcinoembryonic antigen-related cell adhesion molecule 5	93	Ig-like 1.					anchored to membrane|basolateral plasma membrane|integral to plasma membrane				breast(1)|endometrium(3)|kidney(5)|large_intestine(4)|lung(10)|ovary(2)|skin(7)|stomach(1)|urinary_tract(1)	34				OV - Ovarian serous cystadenocarcinoma(3;0.00278)|all cancers(3;0.00625)|Epithelial(262;0.0379)|GBM - Glioblastoma multiforme(1328;0.142)		TACCCCAGGGCCCGCATACAG	0.458000													114	115					0	0	1	0	0
SULT6B1	391365	broad.mit.edu	37	2	37406671	37406671	+	Missense_Mutation	SNP	G	G	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr2:37406671G>T	ENST00000535679.1	-	4	458	c.459C>A	c.(457-459)caC>caA	p.H153Q	SULT6B1_ENST00000407963.1_Missense_Mutation_p.H115Q|SULT6B1_ENST00000260637.3_Missense_Mutation_p.H115Q|SULT6B1_ENST00000379149.2_Intron			Q6IMI4	ST6B1_HUMAN	sulfotransferase family, cytosolic, 6B, member 1	153						cytoplasm	sulfotransferase activity			NS(1)|breast(1)|central_nervous_system(1)|large_intestine(3)|lung(5)|ovary(1)	12		all_hematologic(82;0.248)				GGACATCGTTGTGGAAATGCA	0.363000													41	63					6.68952e-21	7.50532e-21	1	1	0
OR2A2	442361	broad.mit.edu	37	7	143807200	143807200	+	Missense_Mutation	SNP	C	C	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr7:143807200C>A	ENST00000408979.2	+	1	594	c.525C>A	c.(523-525)caC>caA	p.H175Q		NM_001005480.2	NP_001005480.2	Q6IF42	OR2A2_HUMAN	olfactory receptor, family 2, subfamily A, member 2	175					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(1)|kidney(1)|large_intestine(2)|lung(13)|prostate(1)|skin(4)	22	Melanoma(164;0.0783)					ATGTGAACCACCTCTTCTGTG	0.522000													29	105					9.39395e-14	1.02886e-13	1	1	0
CAPG	822	broad.mit.edu	37	2	85628999	85628999	+	Silent	SNP	C	C	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr2:85628999C>T	ENST00000263867.4	-	3	354	c.105G>A	c.(103-105)gcG>gcA	p.A35A	CAPG_ENST00000409921.1_Silent_p.A35A|CAPG_ENST00000409724.1_Silent_p.A35A|CAPG_ENST00000409670.1_Silent_p.A35A	NM_001256140.1|NM_001747.3	NP_001243069.1|NP_001738.2	P40121	CAPG_HUMAN	capping protein (actin filament), gelsolin-like	35					barbed-end actin filament capping|protein complex assembly	F-actin capping protein complex|melanosome|nuclear membrane|nucleolus	actin binding			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(1)|lung(6)	11						GGTTCTCTTGCGCCACAGGCA	0.597000													4	129					0	0	1	0	0
CYP2B7P	1556	broad.mit.edu	37	19	41447337	41447337	+	RNA	SNP	C	C	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:41447337C>T	ENST00000599198.1	+	0	836					NR_001278.1															NS(1)|endometrium(6)|kidney(1)|lung(2)|ovary(1)|skin(1)	12						CCCAGCGCCCCCAGGGACCTC	0.557000													48	112					0	0	1	0	0
ZNF773	374928	broad.mit.edu	37	19	58018415	58018415	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:58018415C>G	ENST00000282292.4	+	4	1092	c.952C>G	c.(952-954)Ctc>Gtc	p.L318V	ZNF773_ENST00000593916.1_Intron|ZNF773_ENST00000599847.1_Intron|ZNF773_ENST00000598770.1_Missense_Mutation_p.L317V	NM_198542.1	NP_940944.1	Q6PK81	ZN773_HUMAN	zinc finger protein 773	318					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(6)|ovary(1)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	22		Colorectal(82;0.000256)|all_neural(62;0.0577)|Ovarian(87;0.221)		UCEC - Uterine corpus endometrioid carcinoma (67;0.168)|GBM - Glioblastoma multiforme(193;0.0254)		CAACTCCAGCCTCATGAAACA	0.423000													15	144					0	0	1	0	0
FAM47C	442444	broad.mit.edu	37	X	37026997	37026997	+	Missense_Mutation	SNP	A	A	C			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chrX:37026997A>C	ENST00000358047.3	+	1	566	c.514A>C	c.(514-516)Act>Cct	p.T172P		NM_001013736.2	NP_001013758.1	Q5HY64	FA47C_HUMAN	family with sequence similarity 47, member C	172										breast(4)|central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(15)|lung(63)|ovary(6)|pancreas(1)|prostate(6)|skin(8)|upper_aerodigestive_tract(4)|urinary_tract(1)	120						GGAGAAGACAACTGACGAACC	0.597000													5	30					0	0	1	0	0
WASH3P	374666	broad.mit.edu	37	15	102516473	102516473	+	RNA	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr15:102516473G>A	ENST00000557932.1	+	0	1421																				central_nervous_system(1)|endometrium(6)|kidney(11)|prostate(5)|stomach(1)|urinary_tract(1)	25						ATCCTAGGGGGCTCCATGACA	0.642000													5	68					0	0	1	0	0
PRR12	57479	broad.mit.edu	37	19	50102938	50102938	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:50102938G>A	ENST00000418929.2	+	5	4100	c.4088G>A	c.(4087-4089)tGc>tAc	p.C1363Y		NM_020719.1	NP_065770.1	Q9ULL5	PRR12_HUMAN	proline rich 12	542							DNA binding			NS(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(2)|pancreas(1)|prostate(2)	11		all_lung(116;2.45e-07)|Lung NSC(112;1.24e-06)|Ovarian(192;0.0728)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00319)|GBM - Glioblastoma multiforme(134;0.0132)		CCTTCACCCTGCAAGCGGCTT	0.642000													3	20					0	0	1	0	0
PPP1R17	10842	broad.mit.edu	37	7	31736577	31736577	+	Splice_Site	SNP	A	A	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr7:31736577A>T	ENST00000342032.3	+	4	863		c.e4-1		PPP1R17_ENST00000498609.1_Splice_Site|PPP1R17_ENST00000409146.3_Splice_Site	NM_006658.4	NP_006649.2	O96001	GSUB_HUMAN	protein phosphatase 1, regulatory subunit 17						behavior|central nervous system development|intracellular protein kinase cascade|protein phosphorylation	soluble fraction											CTAACCATGCAGGTGTGTTTT	0.373000													21	35					0	0	1	0	0
ANKRD36C	400986	broad.mit.edu	37	2	96593000	96593000	+	Missense_Mutation	SNP	A	A	G	rs111976783		TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr2:96593000A>G	ENST00000456556.1	-	28	1985	c.1901T>C	c.(1900-1902)aTa>aCa	p.I634T						ankyrin repeat domain 36C									p.I634T(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						TTCTGTGGCTATATTTGAAAC	0.338000													4	71					0	0	1	0	0
PSG11	5680	broad.mit.edu	37	19	43528993	43528993	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr19:43528993C>T	ENST00000401740.1	-	2	383	c.280G>A	c.(280-282)Gca>Aca	p.A94T	PSG11_ENST00000403486.1_Intron|PSG11_ENST00000320078.7_Missense_Mutation_p.A94T|PSG11_ENST00000306322.7_Intron			Q9UQ72	PSG11_HUMAN	pregnancy specific beta-1-glycoprotein 11	94	Ig-like V-type.				female pregnancy	extracellular region				breast(1)|endometrium(2)|kidney(1)|large_intestine(3)|lung(15)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	26		Prostate(69;0.00682)				CCACTGTATGCCGGTCCATAT	0.443000													5	287					0	0	1	0	0
SLC27A4	10999	broad.mit.edu	37	9	131118065	131118065	+	Silent	SNP	G	G	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr9:131118065G>A	ENST00000300456.3	+	12	1881	c.1764G>A	c.(1762-1764)ctG>ctA	p.L588L	SLC27A4_ENST00000372870.1_Silent_p.L182L	NM_005094.3	NP_005085.2	Q6P1M0	S27A4_HUMAN	solute carrier family 27 (fatty acid transporter), member 4	588					long-chain fatty acid transport|transmembrane transport	integral to membrane	fatty acid transporter activity|nucleotide binding|protein binding			autonomic_ganglia(1)|kidney(1)|large_intestine(1)|lung(7)|ovary(1)|prostate(2)	13						TGCCTGAGCTGCACAAAACAG	0.612000													4	93					0	0	1	0	0
TIMELESS	8914	broad.mit.edu	37	12	56822781	56822781	+	Missense_Mutation	SNP	C	C	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr12:56822781C>A	ENST00000229201.4	-	11	1341	c.1187G>T	c.(1186-1188)gGc>gTc	p.G396V	TIMELESS_ENST00000554616.1_Intron|TIMELESS_ENST00000553532.1_Missense_Mutation_p.G397V	NM_003920.3	NP_003911.2	Q9UNS1	TIM_HUMAN	timeless circadian clock	397					cell division|circadian rhythm|detection of abiotic stimulus|mitosis|morphogenesis of an epithelium|negative regulation of transcription, DNA-dependent|regulation of S phase|response to DNA damage stimulus|transcription, DNA-dependent	nuclear chromatin				NS(1)|breast(2)|cervix(3)|endometrium(3)|kidney(3)|large_intestine(8)|lung(14)|ovary(7)|pancreas(2)|prostate(3)|skin(1)|stomach(1)|urinary_tract(1)	49						AGAAACCAGGCCTGGCCGGAA	0.537000													27	25					4.22769e-11	4.52265e-11	1	1	0
BCRP7	100133163	broad.mit.edu	37	22	18844704	18844704	+	RNA	SNP	T	T	C			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr22:18844704T>C	ENST00000412938.1	+	0	2954																											TGGGTTAAAATTCCGACCATG	0.562000													3	4					0	0	1	0	0
ANKRD36C	400986	broad.mit.edu	37	2	96593025	96593025	+	Missense_Mutation	SNP	C	C	T	rs75189823	by1000genomes	TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr2:96593025C>T	ENST00000456556.1	-	28	1960	c.1876G>A	c.(1876-1878)Gat>Aat	p.D626N						ankyrin repeat domain 36C									p.D626N(1)		breast(1)|endometrium(8)|kidney(5)|lung(4)	18						TCTTTCTCATCACTTGTAGCC	0.318000													4	61					0	0	1	0	0
CMYA5	202333	broad.mit.edu	37	5	79031172	79031172	+	Missense_Mutation	SNP	A	A	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr5:79031172A>G	ENST00000446378.2	+	2	6615	c.6584A>G	c.(6583-6585)aAa>aGa	p.K2195R		NM_153610.3	NP_705838.3	Q8N3K9	CMYA5_HUMAN	cardiomyopathy associated 5	2195						perinuclear region of cytoplasm				NS(2)|breast(4)|central_nervous_system(1)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|kidney(4)|large_intestine(37)|lung(34)|ovary(6)|pancreas(2)|prostate(5)|skin(5)|stomach(11)|upper_aerodigestive_tract(3)|urinary_tract(1)	128		Lung NSC(167;0.00296)|all_lung(232;0.00327)|Ovarian(174;0.0262)		OV - Ovarian serous cystadenocarcinoma(54;9.85e-46)|Epithelial(54;3.38e-40)|all cancers(79;3.43e-35)		CCAGATAACAAAGTTGCTGAA	0.418000													5	80					0	0	1	0	0
POM121L9P	29774	broad.mit.edu	37	22	24659578	24659578	+	RNA	SNP	A	A	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr22:24659578A>G	ENST00000414583.2	+	0	3103					NR_003714.1																						TGCGCAGGCCAACACTCACTG	0.617000													3	10					0	0	1	0	0
PRKAA2	5563	broad.mit.edu	37	1	57111088	57111089	+	Frame_Shift_Ins	INS	-	-	G			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr1:57111088_57111089insG	ENST00000371244.4	+	1	94_95	c.28_29insG	c.(28-30)ggtfs	p.G10fs		NM_006252.3	NP_006243.2	P54646	AAPK2_HUMAN	protein kinase, AMP-activated, alpha 2 catalytic subunit	10					carnitine shuttle|cell cycle arrest|cholesterol biosynthetic process|energy reserve metabolic process|fatty acid biosynthetic process|insulin receptor signaling pathway|regulation of fatty acid biosynthetic process|regulation of fatty acid oxidation	cytosol|nucleoplasm	ATP binding|metal ion binding			breast(6)|endometrium(1)|large_intestine(6)|lung(7)|ovary(1)|prostate(1)|stomach(1)	23						GCACGACGGGCGGGTGAAGATC	0.703													2	4	---	---	---	---					
RP11-242J7.1	0	broad.mit.edu	37	4	185536410	185536413	+	RNA	DEL	TTTG	TTTG	-	rs146473442		TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr4:185536410_185536413delTTTG	ENST00000522554.1	-	0	292																											CAAAGCCGATtttgtttgtttgtt	0.451													5	3	---	---	---	---					
TRBV5-6	28609	broad.mit.edu	37	7	142131738	142131739	+	RNA	INS	-	-	A			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr7:142131738_142131739insA	ENST00000390375.2	-	0	90																											ATGAGCACAGGGACAGCCTGGA	0.579													8	63	---	---	---	---					
CREB3	10488	broad.mit.edu	37	9	35736088	35736089	+	Frame_Shift_Del	DEL	GA	GA	-			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr9:35736088_35736089delGA	ENST00000353704.2	+	7	1093_1094	c.655_656delGA	c.(655-657)gfs	p.E219fs	CREB3_ENST00000486056.1_3'UTR	NM_006368.4	NP_006359.3	O43889	CREB3_HUMAN	cAMP responsive element binding protein 3	243	Leucine-zipper.				chemotaxis|induction of positive chemotaxis|interspecies interaction between organisms|negative regulation of cell cycle|positive regulation of calcium ion transport|positive regulation of cell migration|positive regulation of transcription, DNA-dependent|reactivation of latent virus|regulation of cell proliferation	cytosol|endoplasmic reticulum|endoplasmic reticulum membrane|Golgi apparatus|integral to membrane|nucleus	cAMP response element binding protein binding|CCR1 chemokine receptor binding|DNA binding|protein dimerization activity|protein homodimerization activity|sequence-specific DNA binding transcription factor activity			endometrium(1)|kidney(2)|large_intestine(3)|lung(2)|urinary_tract(1)	9	all_epithelial(49;0.167)		Lung(28;0.00276)|LUSC - Lung squamous cell carcinoma(32;0.00418)|STAD - Stomach adenocarcinoma(86;0.194)	GBM - Glioblastoma multiforme(74;0.0285)		CATGGTGATTGAGATATCAAAC	0.520											OREG0019176	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	66	84	---	---	---	---					
WDR73	84942	broad.mit.edu	37	15	85186877	85186894	+	In_Frame_Del	DEL	CTTGGCTCCGTGTTCCAT	CTTGGCTCCGTGTTCCAT	-	rs143462247		TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr15:85186877_85186894delCTTGGCTCCGTGTTCCAT	ENST00000434634.2	-	8	1004_1021	c.944_961delATGGAACACGGAGCCAAG	c.(943-963)gta>g	p.DGTRSQV315del	WDR73_ENST00000398528.3_5'UTR	NM_032856.2	NP_116245.2	Q6P4I2	WDR73_HUMAN	WD repeat domain 73	315										cervix(1)|large_intestine(1)|lung(1)	3						AGAGGTTCTACTTGGCTCCGTGTTCCATCTTGGCTCCG	0.509													6	9	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11085531	11085533	+	RNA	DEL	AAA	AAA	-			TCGA-QR-A70O-01A-11D-A35D-08	TCGA-QR-A70O-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	4776a3fb-8da7-4565-9c39-9427b044c297	78f8c217-e394-49cf-bf5a-e75c85240160	g.chr21:11085531_11085533delAAA	ENST00000470054.1	-	0	324									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		caccaccactaaaaccacgacca	0.596													4	4	---	---	---	---