Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
MST1L	11223	broad.mit.edu	37	1	17083685	17083685	+	RNA	SNP	C	C	A	rs3197973	by1000genomes	TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr1:17083685C>A	ENST00000455405.2	-	0	903																											ACTGTACTTACAAGTTTTGTC	0.403000													4	12					0.27861	0.27861	1	1	0
FAM194A	131831	broad.mit.edu	37	3	150377880	150377880	+	Silent	SNP	C	C	T			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr3:150377880C>T	ENST00000295910.6	-	14	1843	c.1791G>A	c.(1789-1791)ctG>ctA	p.L597L	FAM194A_ENST00000491361.1_Silent_p.L451L	NM_152394.3	NP_689607.2	Q7L0X2	F194A_HUMAN	family with sequence similarity 194, member A	597										NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(3)|kidney(1)|large_intestine(10)|lung(14)|ovary(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)	38						TTAAACTGGCCAGCAGAAGAA	0.438000													22	66					0	0	1	0	0
AFAP1L1	134265	broad.mit.edu	37	5	148679174	148679174	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr5:148679174T>C	ENST00000296721.4	+	2	217	c.119T>C	c.(118-120)aTc>aCc	p.I40T	AFAP1L1_ENST00000515000.1_Missense_Mutation_p.I40T|AFAP1L1_ENST00000522492.1_3'UTR	NM_001146337.1|NM_152406.2	NP_001139809.1|NP_689619.1	Q8TED9	AF1L1_HUMAN	actin filament associated protein 1-like 1	40							protein binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(6)|liver(1)|lung(10)|ovary(1)|pancreas(1)|skin(2)	26			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GTGGCCTCCATCCTGCAGAGC	0.602000													6	42					0	0	1	0	0
GAS2L2	246176	broad.mit.edu	37	17	34072885	34072885	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr17:34072885T>C	ENST00000254466.6	-	6	1658	c.1631A>G	c.(1630-1632)gAc>gGc	p.D544G	GAS2L2_ENST00000587565.1_Missense_Mutation_p.D528G	NM_139285.3	NP_644814.1	Q8NHY3	GA2L2_HUMAN	growth arrest-specific 2 like 2	544					cell cycle arrest	cytoplasm|cytoskeleton				central_nervous_system(1)|endometrium(1)|large_intestine(7)|lung(14)|ovary(2)|pancreas(1)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	35		Ovarian(249;0.17)		UCEC - Uterine corpus endometrioid carcinoma (308;0.0182)		CCCAGCCAGGTCCACAGTGAC	0.617000													3	27					0	0	1	0	0
GMPR	2766	broad.mit.edu	37	6	16274725	16274725	+	Missense_Mutation	SNP	C	C	T			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr6:16274725C>T	ENST00000259727.4	+	5	659	c.545C>T	c.(544-546)cCa>cTa	p.P182L		NM_006877.3	NP_006868.3	P36959	GMPR1_HUMAN	guanosine monophosphate reductase	182					nucleotide metabolic process|purine base metabolic process|purine-containing compound salvage|response to cold	cytosol	GMP reductase activity|metal ion binding			NS(1)|breast(1)|cervix(1)|endometrium(4)|kidney(2)|large_intestine(5)|lung(5)|ovary(1)	20	Breast(50;0.0427)|Ovarian(93;0.103)	all_hematologic(90;0.0895)				GGAGTTGGACCAGGTAAGACT	0.512000													7	39					0	0	1	0	0
SAMD9L	219285	broad.mit.edu	37	7	92763379	92763379	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr7:92763379G>A	ENST00000318238.4	-	5	3122	c.1906C>T	c.(1906-1908)Ccc>Tcc	p.P636S	SAMD9L_ENST00000437805.1_Missense_Mutation_p.P636S|SAMD9L_ENST00000411955.1_Missense_Mutation_p.P636S	NM_152703.2	NP_689916.2	Q8IVG5	SAM9L_HUMAN	sterile alpha motif domain containing 9-like	636										central_nervous_system(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(23)|liver(2)|lung(31)|ovary(5)|prostate(2)|skin(6)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(4)	88	all_cancers(62;4.15e-11)|all_epithelial(64;2.29e-10)|Breast(17;0.000675)|Lung NSC(181;0.0755)|all_lung(186;0.0989)		STAD - Stomach adenocarcinoma(171;0.000302)			CCACGGGCGGGCAAAAACCTT	0.398000													4	121					0	0	1	0	0
ABCB5	340273	broad.mit.edu	37	7	20698192	20698192	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr7:20698192G>A	ENST00000404938.2	+	14	2252	c.1600G>A	c.(1600-1602)Gca>Aca	p.A534T	ABCB5_ENST00000258738.6_Missense_Mutation_p.A89T|ABCB5_ENST00000443026.2_Missense_Mutation_p.A89T|ABCB5_ENST00000406935.1_Missense_Mutation_p.A89T	NM_001163941.1	NP_001157413.1	Q2M3G0	ABCB5_HUMAN	ATP-binding cassette, sub-family B (MDR/TAP), member 5	89	ABC transmembrane type-1.				regulation of membrane potential	apical plasma membrane|Golgi membrane|integral to plasma membrane|intercellular canaliculus	ATP binding|ATPase activity, coupled to transmembrane movement of substances|efflux transmembrane transporter activity			breast(2)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(11)|liver(1)|lung(37)|ovary(1)|pancreas(1)|prostate(1)|skin(10)|upper_aerodigestive_tract(1)	77						ACAGAGGATCGCAATTGCTCG	0.433000													10	34					0	0	1	0	0
BCOR	54880	broad.mit.edu	37	X	39911406	39911406	+	Missense_Mutation	SNP	C	C	G			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chrX:39911406C>G	ENST00000342274.4	-	15	5484	c.5122G>C	c.(5122-5124)Gag>Cag	p.E1708Q	BCOR_ENST00000378455.4_Missense_Mutation_p.E1690Q|BCOR_ENST00000397354.3_Missense_Mutation_p.E1708Q|BCOR_ENST00000378444.4_Missense_Mutation_p.E1742Q|BCOR_ENST00000378463.1_Missense_Mutation_p.E585Q	NM_001123383.1	NP_001116855.1	Q6W2J9	BCOR_HUMAN	BCL6 corepressor	1742					heart development|histone H2A monoubiquitination|negative regulation of bone mineralization|negative regulation of histone H3-K36 methylation|negative regulation of histone H3-K4 methylation|negative regulation of tooth mineralization|negative regulation of transcription from RNA polymerase II promoter|odontogenesis|palate development|specification of axis polarity|transcription, DNA-dependent	nucleus	heat shock protein binding|histone deacetylase binding|transcription corepressor activity|transcription factor binding|transcription regulatory region DNA binding			breast(4)|central_nervous_system(11)|cervix(1)|endometrium(24)|eye(6)|haematopoietic_and_lymphoid_tissue(33)|kidney(2)|large_intestine(11)|lung(22)|ovary(2)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	126						TGGAGCCACTCTACAGAGGAG	0.493000			"""F, N, S, T"""	RARA	"""retinoblastoma, AML, APL(translocation)"""		oculo-facio-cardio-dental genetic						3	26					0	0	1	0	0
CROCCP2	84809	broad.mit.edu	37	1	16956575	16956575	+	RNA	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr1:16956575G>A	ENST00000412962.1	-	0	294																											TCTCGCTGTCGCTAAGCTGCT	0.647000													3	30					0	0	1	0	0
BZRAP1	9256	broad.mit.edu	37	17	56386005	56386005	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr17:56386005T>C	ENST00000355701.3	-	22	5498	c.4628A>G	c.(4627-4629)aAt>aGt	p.N1543S	BZRAP1_ENST00000343736.4_Missense_Mutation_p.N1543S|BZRAP1_ENST00000268893.6_Missense_Mutation_p.N1483S	NM_001261835.1|NM_004758.3	NP_001248764.1|NP_004749.2	O95153	RIMB1_HUMAN	benzodiazapine receptor (peripheral) associated protein 1	1543						mitochondrion	benzodiazepine receptor binding			cervix(1)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|liver(2)|lung(16)|ovary(1)|prostate(1)|skin(6)|upper_aerodigestive_tract(2)|urinary_tract(1)	54	Medulloblastoma(34;0.127)|all_neural(34;0.237)					GGGGCCTGAATTGGCCTTCGG	0.677000													8	14					0	0	1	0	0
MTOR	2475	broad.mit.edu	37	1	11169377	11169377	+	Missense_Mutation	SNP	T	T	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr1:11169377T>A	ENST00000361445.4	-	56	7574	c.7498A>T	c.(7498-7500)Att>Ttt	p.I2500F	MTOR_ENST00000376838.1_Missense_Mutation_p.I705F	NM_004958.3	NP_004949.1	P42345	MTOR_HUMAN	mechanistic target of rapamycin (serine/threonine kinase)	2500	PI3K/PI4K.				cell growth|cellular response to hypoxia|insulin receptor signaling pathway|nerve growth factor receptor signaling pathway|peptidyl-serine phosphorylation|phosphatidylinositol-mediated signaling|protein autophosphorylation|protein catabolic process|response to amino acid stimulus|response to nutrient|T cell costimulation|TOR signaling cascade	endoplasmic reticulum membrane|Golgi membrane|lysosome|mitochondrial outer membrane|phosphatidylinositol 3-kinase complex|PML body|TORC1 complex|TORC2 complex	ATP binding|phosphoprotein binding|protein serine/threonine kinase activity			breast(5)|central_nervous_system(7)|endometrium(20)|kidney(34)|large_intestine(21)|lung(43)|ovary(9)|prostate(3)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	149						CTGTTAATAATCTGGATAGCT	0.408000													16	52					0	0	1	0	0
ZNF319	57567	broad.mit.edu	37	16	58032116	58032116	+	Silent	SNP	T	T	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr16:58032116T>A	ENST00000299237.2	-	2	676	c.54A>T	c.(52-54)ccA>ccT	p.P18P		NM_020807.1	NP_065858.1	Q9P2F9	ZN319_HUMAN	zinc finger protein 319	18	Pro-rich.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			large_intestine(2)|lung(4)|ovary(1)|urinary_tract(1)	8						GAGGCTGCGGTGGCTGTGGCT	0.637000													11	44					0	0	1	0	0
SMC4	10051	broad.mit.edu	37	3	160142806	160142806	+	Splice_Site	SNP	A	A	G			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr3:160142806A>G	ENST00000357388.3	+	16	2928	c.2478_splice	c.e16+1	p.Q826_splice	RP11-432B6.3_ENST00000483754.1_Intron|SMC4_ENST00000360111.2_Splice_Site_p.Q826_splice|SMC4_ENST00000462787.1_Splice_Site_p.Q826_splice|SMC4_ENST00000469762.1_Splice_Site_p.Q801_splice|SMC4_ENST00000344722.5_Splice_Site_p.Q826_splice	NM_001002800.1	NP_001002800.1	Q9NTJ3	SMC4_HUMAN	structural maintenance of chromosomes 4	826					cell division|mitotic chromosome condensation	condensin complex|cytoplasm|nucleus	ATP binding|protein heterodimerization activity			breast(2)|central_nervous_system(1)|endometrium(4)|kidney(1)|large_intestine(15)|lung(20)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	48			Lung(72;0.00334)|LUSC - Lung squamous cell carcinoma(72;0.00523)			GCAAGCATCCAGgtatgtgtg	0.363000													3	16					0	0	1	0	0
SCAF8	22828	broad.mit.edu	37	6	155126575	155126575	+	Silent	SNP	A	A	C			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr6:155126575A>C	ENST00000367178.3	+	9	1512	c.936A>C	c.(934-936)ctA>ctC	p.L312L	SCAF8_ENST00000367186.4_Silent_p.L378L|SCAF8_ENST00000417268.1_Silent_p.L312L	NM_014892.3	NP_055707.3	Q9UPN6	SCAF8_HUMAN	SR-related CTD-associated factor 8	312	Gln-rich.				mRNA processing|RNA splicing	nuclear matrix|spliceosomal complex	nucleotide binding|RNA binding|RNA polymerase core enzyme binding			breast(4)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(14)|lung(15)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)	46						AGCAAAACCTAGAACATCTCA	0.358000													7	69					0	0	1	0	0
COL5A3	50509	broad.mit.edu	37	19	10089840	10089840	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr19:10089840G>A	ENST00000264828.3	-	39	2927	c.2842C>T	c.(2842-2844)Ctt>Ttt	p.L948F		NM_015719.3	NP_056534.2	P25940	CO5A3_HUMAN	collagen, type V, alpha 3	948	Triple-helical region.				collagen fibril organization|skin development	collagen type V	collagen binding|extracellular matrix structural constituent			NS(2)|breast(3)|central_nervous_system(2)|endometrium(11)|kidney(23)|large_intestine(12)|liver(2)|lung(35)|ovary(8)|prostate(5)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	116			Epithelial(33;7.11e-05)			AGGCCAGGAAGACCTTGTTCA	0.567000													8	36					0	0	1	0	0
LLPH	84298	broad.mit.edu	37	12	66517700	66517700	+	Missense_Mutation	SNP	T	T	C			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr12:66517700T>C	ENST00000266604.2	-	3	380	c.310A>G	c.(310-312)Agg>Ggg	p.R104G	LLPH_ENST00000446587.2_Missense_Mutation_p.R104G|TMBIM4_ENST00000539652.1_3'UTR	NM_032338.3	NP_115714.1	Q9BRT6	LLPH_HUMAN	LLP homolog, long-term synaptic facilitation (Aplysia)	104	Lys-rich.									central_nervous_system(1)|cervix(1)|kidney(1)|large_intestine(1)|skin(1)	5						GCCTTCAGCCTTTTTCTTTGC	0.408000													5	135					0	0	1	0	0
DPEP1	1800	broad.mit.edu	37	16	89702399	89702399	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr16:89702399G>A	ENST00000393092.3	+	3	479	c.188G>A	c.(187-189)gGc>gAc	p.G63D	DPEP1_ENST00000261615.4_Missense_Mutation_p.G63D|DPEP1_ENST00000421184.1_Missense_Mutation_p.G63D	NM_004413.3	NP_004404.1	P16444	DPEP1_HUMAN	dipeptidase 1 (renal)	63					proteolysis	anchored to membrane|apical plasma membrane|microvillus membrane	dipeptidase activity|dipeptidyl-peptidase activity|metal ion binding|metalloexopeptidase activity|protein binding			large_intestine(2)|lung(10)|prostate(1)|urinary_tract(1)	14		all_lung(18;0.0054)|all_hematologic(23;0.094)		BRCA - Breast invasive adenocarcinoma(80;0.0258)	Cilastatin(DB01597)	ACCTTGGCCGGCACACACACC	0.637000													3	19					0	0	1	0	0
TENM1	10178	broad.mit.edu	37	X	123526098	123526098	+	Missense_Mutation	SNP	T	T	G			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chrX:123526098T>G	ENST00000422452.2	-	28	5555	c.5492A>C	c.(5491-5493)gAc>gCc	p.D1831A	TENM1_ENST00000371130.3_Missense_Mutation_p.D1824A|STAG2_ENST00000469481.1_Intron	NM_001163278.1|NM_001163279.1	NP_001156750.1|NP_001156751.1			teneurin transmembrane protein 1																		CCCAGTCTGGTCATAAAGAAT	0.423000													36	54					0	0	1	0	0
MYOM1	8736	broad.mit.edu	37	18	3188963	3188963	+	Missense_Mutation	SNP	G	G	A			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr18:3188963G>A	ENST00000356443.4	-	4	887	c.554C>T	c.(553-555)aCg>aTg	p.T185M	MYOM1_ENST00000261606.7_Missense_Mutation_p.T185M|MYOM1_ENST00000400569.3_Missense_Mutation_p.T185M	NM_003803.3|NM_019856.1	NP_003794.3|NP_062830.1	P52179	MYOM1_HUMAN	myomesin 1	185	6 X 6 AA tandem repeats.					striated muscle myosin thick filament	structural constituent of muscle			NS(2)|autonomic_ganglia(1)|central_nervous_system(2)|endometrium(15)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(15)|lung(20)|ovary(4)|pancreas(1)|prostate(4)|skin(1)|stomach(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	77						CTTGGATGCCGTGGACTGTTT	0.507000													4	73					0	0	1	0	0
HSPG2	3339	broad.mit.edu	37	1	22199255	22199255	+	Splice_Site	DEL	T	T	-			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr1:22199255delT	ENST00000374695.3	-	32	3968		c.e32-2			NM_005529.5	NP_005520.4	P98160	PGBM_HUMAN	heparan sulfate proteoglycan 2						angiogenesis|cell adhesion|lipid metabolic process|lipoprotein metabolic process	basement membrane|extracellular space|plasma membrane	protein C-terminus binding			breast(6)|central_nervous_system(1)|cervix(1)|endometrium(12)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(15)|liver(1)|lung(44)|ovary(10)|pancreas(1)|prostate(10)|skin(9)|upper_aerodigestive_tract(3)|urinary_tract(3)	127		Colorectal(325;3.46e-05)|all_lung(284;7.93e-05)|Lung NSC(340;8.71e-05)|Renal(390;0.000219)|Breast(348;0.00222)|Ovarian(437;0.00308)|Myeloproliferative disorder(586;0.0255)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0498)|OV - Ovarian serous cystadenocarcinoma(117;1.14e-26)|Colorectal(126;4.18e-07)|COAD - Colon adenocarcinoma(152;1.82e-05)|GBM - Glioblastoma multiforme(114;3.13e-05)|BRCA - Breast invasive adenocarcinoma(304;0.000756)|STAD - Stomach adenocarcinoma(196;0.00656)|KIRC - Kidney renal clear cell carcinoma(1967;0.00942)|READ - Rectum adenocarcinoma(331;0.0721)|Lung(427;0.223)	Becaplermin(DB00102)|Palifermin(DB00039)	CACCTGGGCCTGGGTAGACGG	0.682													2	4	---	---	---	---					
FER1L5	90342	broad.mit.edu	37	2	97361186	97361186	+	RNA	DEL	G	G	-			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr2:97361186delG	ENST00000457909.1	+	0	3185							A0AVI2	FR1L5_HUMAN	fer-1-like 5 (C. elegans)							integral to membrane				NS(1)|autonomic_ganglia(1)|breast(4)|cervix(1)|endometrium(9)|large_intestine(9)|lung(6)|ovary(2)|prostate(2)|skin(1)|urinary_tract(2)	38						TCTCTGGCCAGGACCCCATTA	0.632													2	4	---	---	---	---					
AC073321.4	0	broad.mit.edu	37	2	217475031	217475032	+	RNA	INS	-	-	AA	rs71401156		TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr2:217475031_217475032insAA	ENST00000441803.1	+	0	195																											AATTTTATTTCAAAAAAAAAAA	0.376													4	5	---	---	---	---					
CDC27	996	broad.mit.edu	37	17	45219612	45219612	+	Frame_Shift_Del	DEL	A	A	-			TCGA-QR-A6GX-01A-11D-A35D-08	TCGA-QR-A6GX-10A-01D-A35B-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7398e690-eed2-486c-8f3e-728337467264	8514d7ec-0a74-4299-af21-f2d46100b2b5	g.chr17:45219612delA	ENST00000066544.3	-	11	1454	c.1361delT	c.(1360-1362)cafs	p.L454fs	CDC27_ENST00000531206.1_Frame_Shift_Del_p.L460fs|CDC27_ENST00000527547.1_Frame_Shift_Del_p.L454fs|CDC27_ENST00000446365.2_Frame_Shift_Del_p.L393fs	NM_001114091.1|NM_001256.3	NP_001107563.1|NP_001247.3	P30260	CDC27_HUMAN	cell division cycle 27	454					anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination	anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule	protein phosphatase binding			NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2)	90						TGCTTTTTGTAGATTAAAGGC	0.308													9	37	---	---	---	---