Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_file Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID Genome_Change Annotation_Transcript Transcript_Strand Transcript_Exon Transcript_Position cDNA_Change Codon_Change Protein_Change Other_Transcripts Refseq_mRNA_Id Refseq_prot_Id SwissProt_acc_Id SwissProt_entry_Id Description UniProt_AApos UniProt_Region UniProt_Site UniProt_Natural_Variations UniProt_Experimental_Info GO_Biological_Process GO_Cellular_Component GO_Molecular_Function COSMIC_overlapping_mutations COSMIC_fusion_genes COSMIC_tissue_types_affected COSMIC_total_alterations_in_gene Tumorscape_Amplification_Peaks Tumorscape_Deletion_Peaks TCGAscape_Amplification_Peaks TCGAscape_Deletion_Peaks DrugBank ref_context gc_content CCLE_ONCOMAP_overlapping_mutations CCLE_ONCOMAP_total_mutations_in_gene CGC_Mutation_Type CGC_Translocation_Partner CGC_Tumor_Types_Somatic CGC_Tumor_Types_Germline CGC_Other_Diseases DNARepairGenes_Role FamilialCancerDatabase_Syndromes MUTSIG_Published_Results OREGANNO_ID OREGANNO_Values t_alt_count t_ref_count validation_alt_allele validation_method validation_status validation_tumor_sample pox qox pox_cutoff isArtifactMode oxoGCut MYH7 4625 broad.mit.edu 37 14 23887583 23887583 + Silent SNP C C T rs144465613 byFrequency TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr14:23887583C>T ENST00000355349.3 - 30 4167 c.4005G>A c.(4003-4005)tcG>tcA p.S1335S NM_000257.2 NP_000248.2 P12883 MYH7_HUMAN myosin, heavy chain 7, cardiac muscle, beta 1335 adult heart development|muscle filament sliding|regulation of heart rate|ventricular cardiac muscle tissue morphogenesis focal adhesion|muscle myosin complex|myosin filament|nucleus|sarcomere actin binding|actin-dependent ATPase activity|ATP binding|calmodulin binding|microfilament motor activity|structural constituent of muscle p.S1335S(3) NS(3)|breast(4)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(3)|kidney(5)|large_intestine(19)|lung(57)|ovary(5)|prostate(9)|skin(5)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(5) 137 all_cancers(95;2.54e-05) GBM - Glioblastoma multiforme(265;0.00725) CATGCCGGGCCGACTGCAGTG 0.662000 5 40 0 0 1 0 0 TUBB3 10381 broad.mit.edu 37 16 90002016 90002016 + Missense_Mutation SNP C C T TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr16:90002016C>T ENST00000304984.5 + 3 3236 c.941C>T c.(940-942)aCg>aTg p.T314M TUBB3_ENST00000555576.1_Intron|TUBB3_ENST00000556922.1_Missense_Mutation_p.T733M|TUBB3_ENST00000315491.7_Missense_Mutation_p.T386M|TUBB3_ENST00000554444.1_Missense_Mutation_p.T314M Q13509 TBB3_HUMAN tubulin, beta 3 class III 386 'de novo' posttranslational protein folding|axon guidance|microtubule-based movement|protein polymerization cytoplasm|microtubule GTP binding|GTPase activity|structural molecule activity cervix(1)|endometrium(2)|kidney(1)|large_intestine(3)|lung(3)|ovary(3)|pancreas(1)|skin(1)|stomach(1)|urinary_tract(1) 17 all_cancers(9;1.69e-11)|Lung NSC(15;8.94e-06)|all_lung(18;1.39e-05)|all_neural(9;0.00581)|all_hematologic(23;0.0194) BRCA - Breast invasive adenocarcinoma(80;0.0273) GAGCAGTTCACGGCCATGTTC 0.622000 4 148 0 0 1 0 0 VPS28 51160 broad.mit.edu 37 8 145649475 145649475 + Missense_Mutation SNP C C T TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr8:145649475C>T ENST00000377348.2 - 9 586 c.497G>A c.(496-498)cGc>cAc p.R166H VPS28_ENST00000292510.4_Missense_Mutation_p.R166H|VPS28_ENST00000529182.1_Missense_Mutation_p.R166H|VPS28_ENST00000526054.1_Missense_Mutation_p.R166H NM_183057.1 NP_898880.1 Q9UK41 VPS28_HUMAN vacuolar protein sorting 28 homolog (S. cerevisiae) 166 VPS28 C-terminal. cellular membrane organization|endosome transport|negative regulation of protein ubiquitination|protein transport cytosol|late endosome membrane|plasma membrane protein binding kidney(1)|large_intestine(1)|lung(4)|prostate(1) 7 all_cancers(97;6.64e-12)|all_epithelial(106;2.89e-10)|Lung NSC(106;5.7e-05)|all_lung(105;0.000174)|Ovarian(258;0.0173)|Acute lymphoblastic leukemia(118;0.155) OV - Ovarian serous cystadenocarcinoma(54;1.08e-41)|Epithelial(56;8.67e-41)|all cancers(56;1.1e-35)|BRCA - Breast invasive adenocarcinoma(115;0.035)|Colorectal(110;0.055) GTGGCTCATGCGGTGCATGGT 0.692000 3 45 0 0 1 0 0 RNASEH2B 79621 broad.mit.edu 37 13 51530586 51530586 + Missense_Mutation SNP T T A rs75254367 TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr13:51530586T>A ENST00000336617.3 + 11 1314 c.915T>A c.(913-915)aaT>aaA p.N305K RNASEH2B_ENST00000422660.1_Intron|RNASEH2B_ENST00000495244.2_3'UTR NM_024570.3 NP_078846.2 Q5TBB1 RNH2B_HUMAN ribonuclease H2, subunit B 305 RNA catabolic process nucleus|ribonuclease H2 complex endometrium(2)|liver(1)|lung(1)|upper_aerodigestive_tract(1) 5 Acute lymphoblastic leukemia(7;1.03e-07)|Breast(56;0.00122)|Lung NSC(96;0.00143)|Prostate(109;0.0047)|Hepatocellular(98;0.152)|Glioma(44;0.236) GBM - Glioblastoma multiforme(99;9e-08) GGGTAAAAAATAAAAAAAAAA 0.299000 5 68 0 0 1 0 0 LMO7 4008 broad.mit.edu 37 13 76375012 76375012 + Missense_Mutation SNP C C T TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr13:76375012C>T ENST00000357063.3 + 8 2071 c.811C>T c.(811-813)Cgt>Tgt p.R271C LMO7_ENST00000465261.2_5'UTR|RP11-29G8.3_ENST00000563635.1_RNA|LMO7_ENST00000321797.8_5'UTR|LMO7_ENST00000341547.4_Missense_Mutation_p.R271C|LMO7_ENST00000526202.1_Missense_Mutation_p.R180C|LMO7_ENST00000377534.3_Missense_Mutation_p.R271C Q8WWI1 LMO7_HUMAN LIM domain 7 271 cytoplasm|nucleus|ubiquitin ligase complex ubiquitin-protein ligase activity|zinc ion binding NS(1)|autonomic_ganglia(1)|breast(2)|endometrium(2)|kidney(2)|large_intestine(20)|lung(15)|ovary(2)|prostate(5)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(2) 56 Breast(118;0.0992) GBM - Glioblastoma multiforme(99;0.0109) GAGAGGGGGGCGTGAAGGTGT 0.448000 4 144 0 0 1 0 0 ZKSCAN1 7586 broad.mit.edu 37 7 99621184 99621184 + Missense_Mutation SNP G G A TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr7:99621184G>A ENST00000324306.6 + 2 289 c.55G>A c.(55-57)Gag>Aag p.E19K ZKSCAN1_ENST00000426572.1_5'UTR|ZKSCAN1_ENST00000535170.1_Intron NM_003439.1 NP_003430.1 P17029 ZKSC1_HUMAN zinc finger with KRAB and SCAN domains 1 19 viral reproduction mitochondrion|nucleus DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding p.E19K(1) breast(2)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(5)|lung(5)|ovary(3)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(1) 25 Lung NSC(181;0.0211)|all_lung(186;0.0323)|Esophageal squamous(72;0.0439) STAD - Stomach adenocarcinoma(171;0.129) GGCTGCACAGGAGAAGGATGG 0.557000 4 49 0 0 1 0 0 KBTBD12 166348 broad.mit.edu 37 3 127646684 127646684 + Missense_Mutation SNP T T C TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr3:127646684T>C ENST00000405109.1 + 3 1615 c.1148T>C c.(1147-1149)aTt>aCt p.I383T KBTBD12_ENST00000492025.1_Intron|KBTBD12_ENST00000343941.4_Intron|KBTBD12_ENST00000405256.1_Missense_Mutation_p.I383T|KBTBD12_ENST00000407609.3_5'UTR Q3ZCT8 KBTBC_HUMAN kelch repeat and BTB (POZ) domain containing 12 383 endometrium(1)|large_intestine(6)|lung(5)|ovary(1) 13 CTGGGCAGTATTCATAATGAC 0.373000 5 99 0 0 1 0 0 HMGB3 3149 broad.mit.edu 37 X 150156360 150156360 + Silent SNP G G A TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chrX:150156360G>A ENST00000325307.7 + 5 672 c.576G>A c.(574-576)gaG>gaA p.E192E HMGB3_ENST00000448905.2_Silent_p.E192E NM_005342.2 NP_005333.2 O15347 HMGB3_HUMAN high mobility group box 3 192 Asp/Glu-rich (acidic). DNA recombination|multicellular organismal development chromosome|nucleus DNA bending activity|double-stranded DNA binding p.E192E(1) endometrium(3)|large_intestine(2)|lung(2)|skin(1) 8 Acute lymphoblastic leukemia(192;6.56e-05) aggaagaagaggaggaggagg 0.443000 5 97 0 0 1 0 0 SIRPB1 10326 broad.mit.edu 37 20 1585397 1585397 + Missense_Mutation SNP T T C rs148754551 by1000genomes TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr20:1585397T>C ENST00000279477.7 - 3 806 c.742A>G c.(742-744)Acc>Gcc p.T248A SIRPB1_ENST00000568365.1_Missense_Mutation_p.T248A|SIRPB1_ENST00000381603.3_Intron|RP4-576H24.4_ENST00000564763.1_Intron|SIRPB1_ENST00000381605.4_Intron NM_001135844.2 NP_001129316.1 O00241 SIRB1_HUMAN signal-regulatory protein beta 1 248 cell junction assembly|cell surface receptor linked signaling pathway integral to plasma membrane protein binding p.T248A(5) central_nervous_system(2)|kidney(2)|large_intestine(4)|lung(16)|ovary(1)|prostate(4)|skin(1)|upper_aerodigestive_tract(1) 31 CCTCGGATGGTCTCAGACAAG 0.627000 4 24 0 0 1 0 0 DNAH9 1770 broad.mit.edu 37 17 11642318 11642318 + Missense_Mutation SNP G G A TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr17:11642318G>A ENST00000262442.3 + 29 6004 c.5936G>A c.(5935-5937)cGc>cAc p.R1979H DNAH9_ENST00000454412.2_Missense_Mutation_p.R1979H NM_001372.3 NP_001363.2 Q9NYC9 DYH9_HUMAN dynein, axonemal, heavy chain 9 1979 AAA 1 (By similarity). cell projection organization|cellular component movement|microtubule-based movement|spermatogenesis axonemal dynein complex|cilium axoneme|cytoplasm|microtubule ATP binding|ATPase activity|microtubule motor activity NS(2)|autonomic_ganglia(1)|breast(15)|central_nervous_system(5)|endometrium(17)|haematopoietic_and_lymphoid_tissue(6)|kidney(17)|large_intestine(49)|liver(2)|lung(123)|ovary(6)|pancreas(1)|prostate(6)|skin(21)|stomach(2)|upper_aerodigestive_tract(13)|urinary_tract(4) 290 Breast(5;0.0122)|all_epithelial(5;0.131) Colorectal(4;6.88e-05)|COAD - Colon adenocarcinoma(4;0.000813)|READ - Rectum adenocarcinoma(10;0.157) TATGCTGGCCGCACAGAGCTG 0.478000 3 46 0 0 1 0 0 HCN2 610 broad.mit.edu 37 19 605212 605212 + Missense_Mutation SNP A A G TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr19:605212A>G ENST00000251287.2 + 3 1261 c.1208A>G c.(1207-1209)aAt>aGt p.N403S NM_001194.3 NP_001185.3 Q9UL51 HCN2_HUMAN hyperpolarization activated cyclic nucleotide-gated potassium channel 2 403 cell-cell signaling|muscle contraction voltage-gated potassium channel complex cAMP binding|protein binding|sodium channel activity|voltage-gated potassium channel activity endometrium(5)|lung(4) 9 all_epithelial(18;2.78e-22)|Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;3.55e-06)|all_lung(49;5.41e-06)|Breast(49;4.08e-05)|Hepatocellular(1079;0.137)|Renal(1328;0.228) UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18) GTGTCCATCAATGGCATGGTG 0.647000 8 35 0 0 1 0 0 IRAK4 51135 broad.mit.edu 37 12 44171441 44171441 + Missense_Mutation SNP A A G TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr12:44171441A>G ENST00000431837.1 + 6 661 c.353A>G c.(352-354)cAt>cGt p.H118R IRAK4_ENST00000551736.1_Missense_Mutation_p.H242R|IRAK4_ENST00000448290.2_Missense_Mutation_p.H242R|IRAK4_ENST00000440781.2_Missense_Mutation_p.H118R NM_001145256.1|NM_001145257.1 NP_001138728.1|NP_001138729.1 Q9NWZ3 IRAK4_HUMAN interleukin-1 receptor-associated kinase 4 242 innate immune response|MyD88-dependent toll-like receptor signaling pathway|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 4 signaling pathway cytosol|endosome membrane|plasma membrane ATP binding|magnesium ion binding|protein serine/threonine kinase activity all_cancers(12;0.00149) Lung NSC(34;0.0804)|all_lung(34;0.181) GBM - Glioblastoma multiforme(48;0.04) AGGTGTCAACATGAAAACTTA 0.303000 16 27 0 0 1 0 0 ZNF780A 284323 broad.mit.edu 37 19 40581529 40581529 + Missense_Mutation SNP C C T TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr19:40581529C>T ENST00000450241.2 - 6 1029 c.718G>A c.(718-720)Gta>Ata p.V240I ZNF780A_ENST00000595687.2_Missense_Mutation_p.V274I|ZNF780A_ENST00000455521.1_Missense_Mutation_p.V275I|ZNF780A_ENST00000594395.1_Missense_Mutation_p.V275I|ZNF780A_ENST00000340963.5_Missense_Mutation_p.V274I|AC005614.5_ENST00000595508.1_RNA|ZNF780A_ENST00000414720.2_Intron O75290 Z780A_HUMAN zinc finger protein 780A 274 regulation of transcription, DNA-dependent|transcription, DNA-dependent nucleus DNA binding|zinc ion binding breast(2)|endometrium(1)|kidney(1)|large_intestine(7)|lung(16)|upper_aerodigestive_tract(3)|urinary_tract(1) 31 all_cancers(60;9.55e-06)|all_lung(34;1.17e-07)|Lung NSC(34;1.41e-07)|Ovarian(47;0.0925) TATGGTTTTACACCAGAATGA 0.388000 6 209 0 0 1 0 0 GPR128 84873 broad.mit.edu 37 3 100328717 100328717 + Missense_Mutation SNP C C T TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr3:100328717C>T ENST00000273352.3 + 1 285 c.17C>T c.(16-18)gCc>gTc p.A6V NM_032787.2 NP_116176.2 Q96K78 GP128_HUMAN G protein-coupled receptor 128 6 neuropeptide signaling pathway integral to membrane|plasma membrane G-protein coupled receptor activity NS(1)|autonomic_ganglia(1)|breast(2)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(9)|liver(2)|lung(20)|ovary(3)|prostate(2)|skin(3)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(2) 56 TCCTGCCGTGCCTGGAACCTT 0.483000 4 45 0 0 1 0 0 ANKRD36BP2 645784 broad.mit.edu 37 2 89083945 89083946 + RNA INS - - GC TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr2:89083945_89083946insGC ENST00000393525.3 + 0 576 GTATTCCTTTTTTTTCAGTGTA 0.347 3 3 --- --- --- --- DPY19L2P2 349152 broad.mit.edu 37 7 102883498 102883498 + RNA DEL A A - TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr7:102883498delA ENST00000312132.4 - 0 2616 GTACCACTGTAAAAAAAAAAA 0.284 3 4 --- --- --- --- RP11-863P13.2 0 broad.mit.edu 37 16 88226611 88226611 + RNA DEL G G - TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr16:88226611delG ENST00000568587.1 - 0 91 tggtggtgatggtggtgatgg 0.522 3 6 --- --- --- --- CDC27 996 broad.mit.edu 37 17 45219612 45219612 + Frame_Shift_Del DEL A A - TCGA-P7-A5NY-01A-12D-A35D-08 TCGA-P7-A5NY-10A-01D-A35B-08 Untested Somatic Phase_I WXS none Illumina GAIIx 68fd9953-4dca-40f6-a422-28b82a371e12 87bae02a-0994-4ce5-a27b-72494a4a1b5f g.chr17:45219612delA ENST00000066544.3 - 11 1454 c.1361delT c.(1360-1362)cafs p.L454fs CDC27_ENST00000531206.1_Frame_Shift_Del_p.L460fs|CDC27_ENST00000446365.2_Frame_Shift_Del_p.L393fs|CDC27_ENST00000527547.1_Frame_Shift_Del_p.L454fs NM_001114091.1|NM_001256.3 NP_001107563.1|NP_001247.3 P30260 CDC27_HUMAN cell division cycle 27 454 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process|cell proliferation|mitotic cell cycle spindle assembly checkpoint|mitotic metaphase/anaphase transition|negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle|protein K11-linked ubiquitination anaphase-promoting complex|centrosome|cytosol|nucleoplasm|spindle microtubule protein phosphatase binding NS(1)|breast(5)|central_nervous_system(3)|cervix(1)|endometrium(2)|kidney(17)|large_intestine(18)|lung(11)|ovary(5)|pancreas(1)|prostate(19)|skin(5)|upper_aerodigestive_tract(2) 90 TGCTTTTTGTAGATTAAAGGC 0.308 7 40 --- --- --- ---