Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HRC	3270	broad.mit.edu	37	19	49657720	49657720	+	Missense_Mutation	SNP	C	C	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr19:49657720C>G	ENST00000252825.4	-	1	961	c.775G>C	c.(775-777)Gat>Cat	p.D259H	HRC_ENST00000595625.1_Missense_Mutation_p.D259H	NM_002152.2	NP_002143.1	P23327	SRCH_HUMAN	histidine rich calcium binding protein	259	4 X tandem repeats, acidic.|6 X approximate tandem repeats.|Asp-rich (acidic).				muscle contraction	sarcoplasmic reticulum lumen	calcium ion binding	p.D259H(1)		endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(10)|lung(10)|ovary(1)|prostate(3)|urinary_tract(2)	34		all_lung(116;3.16e-06)|Lung NSC(112;6.25e-06)|all_neural(266;0.0189)|Ovarian(192;0.0392)		all cancers(93;2.01e-05)|OV - Ovarian serous cystadenocarcinoma(262;0.00019)|GBM - Glioblastoma multiforme(486;0.00279)|Epithelial(262;0.00622)		Acatcatcatcatcatcatca	0.488000													4	34					0	0	0.009096	0	0
CNTNAP4	85445	broad.mit.edu	37	16	76486488	76486488	+	Missense_Mutation	SNP	C	C	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:76486488C>A	ENST00000307431.8	+	9	1537	c.1152C>A	c.(1150-1152)gaC>gaA	p.D384E	CNTNAP4_ENST00000377504.4_Missense_Mutation_p.D336E|CNTNAP4_ENST00000469589.1_3'UTR|CNTNAP4_ENST00000478060.1_Missense_Mutation_p.D312E|CNTNAP4_ENST00000476707.1_Missense_Mutation_p.D388E	NM_033401.3	NP_207837.2	Q9C0A0	CNTP4_HUMAN	contactin associated protein-like 4	385					cell adhesion|signal transduction	integral to membrane	receptor binding	p.D384E(1)|p.D312E(1)|p.D360E(1)		breast(4)|central_nervous_system(1)|cervix(3)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(6)|lung(33)|ovary(2)|pancreas(1)|prostate(3)|upper_aerodigestive_tract(1)	64						CACTGCCAGACTTCTCTGGAG	0.438000													11	155					3.86212e-05	4.7421e-05	0.008291	1	0
IGHV1OR16-3	28313	broad.mit.edu	37	16	32070612	32070612	+	RNA	SNP	A	A	C			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:32070612A>C	ENST00000566806.1	-	0	499																											GGTCTCCTGCAAGGCTTCTGG	0.552000													3	85					0	0	0.009096	0	0
RPS6KA3	6197	broad.mit.edu	37	X	20195194	20195194	+	Missense_Mutation	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:20195194A>G	ENST00000379565.3	-	11	1061	c.854T>C	c.(853-855)cTt>cCt	p.L285P	RPS6KA3_ENST00000540702.1_Missense_Mutation_p.L257P|RPS6KA3_ENST00000544447.1_Missense_Mutation_p.L257P|RPS6KA3_ENST00000379548.4_Missense_Mutation_p.L256P	NM_004586.2	NP_004577.1	P51812	KS6A3_HUMAN	ribosomal protein S6 kinase, 90kDa, polypeptide 3	285	Protein kinase 1.				axon guidance|central nervous system development|innate immune response|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|nerve growth factor receptor signaling pathway|skeletal system development|stress-activated MAPK cascade|synaptic transmission|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|nucleoplasm	ATP binding|caspase inhibitor activity|magnesium ion binding|protein serine/threonine kinase activity	p.L285P(1)		breast(4)|central_nervous_system(4)|endometrium(3)|kidney(2)|large_intestine(5)|liver(14)|lung(7)|ovary(1)|stomach(1)	41						TGGCATTCCAAGTTTGGCTCT	0.284000													45	154					0	0	0.014410	0	0
DCAF12L2	340578	broad.mit.edu	37	X	125298988	125298988	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:125298988C>T	ENST00000538699.1	-	2	1000	c.920G>A	c.(919-921)cGa>cAa	p.R307Q	DCAF12L2_ENST00000360028.2_Missense_Mutation_p.R307Q	NM_001013628.2	NP_001013650.1	Q5VW00	DC122_HUMAN	DDB1 and CUL4 associated factor 12-like 2	307								p.R307Q(2)		NS(2)|central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(11)|lung(36)|ovary(2)|pancreas(1)|skin(2)|upper_aerodigestive_tract(3)	64						CACATTCTCTCGGCAGTAGGG	0.607000													23	245					0	0	0.003954	0	0
MAP2K7	5609	broad.mit.edu	37	19	7975197	7975197	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr19:7975197G>A	ENST00000545011.1	+	4	577	c.512G>A	c.(511-513)gGc>gAc	p.G171D	MAP2K7_ENST00000397981.3_Missense_Mutation_p.G129D|MAP2K7_ENST00000397979.3_Missense_Mutation_p.G129D|MAP2K7_ENST00000397983.3_Missense_Mutation_p.G145D			O14733	MP2K7_HUMAN	mitogen-activated protein kinase kinase 7	129	Protein kinase.				activation of JUN kinase activity|innate immune response|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|nucleus	ATP binding|JUN kinase kinase activity|magnesium ion binding|protein binding|protein kinase binding|protein phosphatase binding|protein serine/threonine kinase activity|protein tyrosine kinase activity	p.G129D(1)		breast(2)|central_nervous_system(3)|endometrium(1)|large_intestine(8)|lung(4)|ovary(1)	19					Etoposide(DB00773)	ATGGGCAGCGGCACCTGCGGC	0.672000													3	18					0	0	0.009096	0	0
PTBP3	9991	broad.mit.edu	37	9	115092722	115092722	+	Splice_Site	SNP	T	T	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr9:115092722T>A	ENST00000334318.6	-	2	227	c.42_splice	c.e2+1	p.K14_splice	PTBP3_ENST00000374255.2_Splice_Site_p.K14_splice|PTBP3_ENST00000487997.1_Intron|PTBP3_ENST00000458258.1_Intron|PTBP3_ENST00000343327.2_Intron|PTBP3_ENST00000374257.1_Intron	NM_001163790.2|NM_005156.6	NP_001157262.1|NP_005147.3	O95758	ROD1_HUMAN	polypyrimidine tract binding protein 3	14					anatomical structure morphogenesis|mRNA processing	nucleus	nucleotide binding|RNA binding	p.K14M(1)									GATTCCTACCTTTAAACCGAC	0.289000													13	62					0	0	0.004990	0	0
BBS10	79738	broad.mit.edu	37	12	76740459	76740459	+	Missense_Mutation	SNP	T	T	C			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr12:76740459T>C	ENST00000393262.3	-	2	1389	c.1306A>G	c.(1306-1308)Acc>Gcc	p.T436A		NM_024685.3	NP_078961.3	Q8TAM1	BBS10_HUMAN	Bardet-Biedl syndrome 10	436					cellular protein metabolic process|nonmotile primary cilium assembly|photoreceptor cell maintenance|response to stimulus|retina homeostasis	cilium	ATP binding	p.T436A(1)		endometrium(2)|kidney(2)|large_intestine(4)|lung(8)|ovary(1)|prostate(1)|skin(1)	19						TGGTCATTGGTTTGTGTCATG	0.368000									Bardet-Biedl syndrome				3	166					0	0	0.004672	0	0
MYEOV2	150678	broad.mit.edu	37	2	241073371	241073371	+	Missense_Mutation	SNP	C	C	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:241073371C>A	ENST00000307266.3	-	2	207	c.208G>T	c.(208-210)Gtt>Ttt	p.V70F	MYEOV2_ENST00000607357.1_Missense_Mutation_p.V39F|MYEOV2_ENST00000489698.1_5'UTR	NM_138336.1	NP_612209.1	Q8WXC6	MYOV2_HUMAN	myeloma overexpressed 2	39								p.V70F(1)		breast(1)|lung(5)|pancreas(1)	7		all_epithelial(40;1.56e-11)|Breast(86;0.0002)|Renal(207;0.00571)|Ovarian(221;0.104)|all_hematologic(139;0.182)|all_lung(227;0.229)|Melanoma(123;0.238)		Epithelial(121;3.81e-30)|all cancers(36;1.1e-27)|OV - Ovarian serous cystadenocarcinoma(60;2.74e-14)|Kidney(56;2.99e-09)|KIRC - Kidney renal clear cell carcinoma(57;3.23e-08)|BRCA - Breast invasive adenocarcinoma(100;8.54e-06)|Lung(119;0.00361)|LUSC - Lung squamous cell carcinoma(224;0.0153)|Colorectal(34;0.0202)|COAD - Colon adenocarcinoma(134;0.143)		TCTGCATGAACGGCCTTTTCA	0.483000													41	103					6.48837e-15	8.99102e-15	0.010771	1	0
DYNLL2	140735	broad.mit.edu	37	17	56166633	56166633	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr17:56166633C>T	ENST00000240343.6	+	3	541	c.263C>T	c.(262-264)tCa>tTa	p.S88L		NM_080677.2	NP_542408.1	Q96FJ2	DYL2_HUMAN	dynein, light chain, LC8-type 2	88					activation of pro-apoptotic gene products|induction of apoptosis by intracellular signals|microtubule-based process|transport	centrosome|cytosol|dynein complex|microtubule|myosin complex|plasma membrane	motor activity	p.S88L(1)		lung(3)	3						CTCTTCAAGTCAGGCTAGGTG	0.532000													6	68					0	0	0.001168	0	0
CCT7	10574	broad.mit.edu	37	2	73467659	73467659	+	Silent	SNP	C	C	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:73467659C>A	ENST00000539919.1	+	4	494	c.123C>A	c.(121-123)tcC>tcA	p.S41S	CCT7_ENST00000398422.2_Intron|CCT7_ENST00000258091.5_Silent_p.S85S|CCT7_ENST00000537131.1_Intron|CCT7_ENST00000538797.1_5'UTR|CCT7_ENST00000540468.1_Intron|CCT7_ENST00000473786.1_Intron	NM_001166285.1	NP_001159757.1	Q99832	TCPH_HUMAN	chaperonin containing TCP1, subunit 7 (eta)	85					'de novo' posttranslational protein folding		ATP binding|unfolded protein binding	p.S85S(1)		breast(1)|cervix(1)|endometrium(1)|lung(3)|stomach(1)	7						TTGCCAAATCCCAAGATGCTG	0.373000													6	48					3.59834e-05	4.47485e-05	0.001168	1	0
ESRP2	80004	broad.mit.edu	37	16	68266596	68266596	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:68266596G>A	ENST00000565858.1	-	7	821	c.735C>T	c.(733-735)ccC>ccT	p.P245P	ESRP2_ENST00000473183.2_Intron	NM_024939.2	NP_079215.2	Q9H6T0	ESRP2_HUMAN	epithelial splicing regulatory protein 2	245					mRNA processing|regulation of RNA splicing|RNA splicing	nucleus	mRNA binding|nucleotide binding	p.?(2)		NS(1)|central_nervous_system(1)|kidney(2)|large_intestine(4)|lung(5)|ovary(1)|prostate(2)	16						TGCTGCTGTAGGGGCAGGGCA	0.587000													24	113					0	0	0.002780	0	0
HS6ST1	9394	broad.mit.edu	37	2	129026419	129026419	+	Nonsense_Mutation	SNP	G	G	A	rs139541363	by1000genomes	TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:129026419G>A	ENST00000259241.6	-	2	566	c.553C>T	c.(553-555)Cga>Tga	p.R185*		NM_004807.2	NP_004798.3	O60243	H6ST1_HUMAN	heparan sulfate 6-O-sulfotransferase 1	185	3'-phosphate binding (Potential).				heparan sulfate proteoglycan biosynthetic process, enzymatic modification	integral to plasma membrane	sulfotransferase activity	p.R185*(2)		endometrium(3)|liver(1)|lung(7)|pancreas(1)|prostate(2)|skin(1)	15	Colorectal(110;0.1)			BRCA - Breast invasive adenocarcinoma(221;0.117)		ACGGGGTCTCGTAGCAGGGTG	0.627000													4	53					0	0	0.003080	0	0
BRD1	23774	broad.mit.edu	37	22	50216780	50216780	+	Silent	SNP	T	T	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr22:50216780T>G	ENST00000216267.8	-	1	1672	c.1186A>C	c.(1186-1188)Agg>Cgg	p.R396R	BRD1_ENST00000404760.1_Silent_p.R396R|BRD1_ENST00000457780.2_Silent_p.R396R|BRD1_ENST00000542442.1_Silent_p.R35R|BRD1_ENST00000404034.1_Silent_p.R396R|BRD1_ENST00000459821.1_5'UTR|BRD1_ENST00000342989.5_5'UTR	NM_014577.1	NP_055392.1	O95696	BRD1_HUMAN	bromodomain containing 1	396					histone H3 acetylation	MOZ/MORF histone acetyltransferase complex	zinc ion binding	p.R396R(1)		endometrium(6)|kidney(3)|large_intestine(5)|lung(17)|ovary(1)|pancreas(1)|prostate(3)|skin(1)	37		all_cancers(38;6.11e-10)|all_epithelial(38;8.06e-09)|all_lung(38;6.64e-05)|Lung NSC(38;0.0011)|Breast(42;0.00235)|Ovarian(80;0.0139)|Lung SC(80;0.164)		UCEC - Uterine corpus endometrioid carcinoma (28;0.0369)|BRCA - Breast invasive adenocarcinoma(115;0.21)		TTCAGAGGCCTCCGGGTGCAG	0.532000													5	209					0	0	0.001168	0	0
TEKT5	146279	broad.mit.edu	37	16	10788536	10788536	+	Silent	SNP	C	C	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:10788536C>A	ENST00000283025.2	-	1	266	c.195G>T	c.(193-195)ccG>ccT	p.P65P		NM_144674.1	NP_653275.1	Q96M29	TEKT5_HUMAN	tektin 5	65					microtubule cytoskeleton organization	cilium axoneme|flagellar axoneme|microtubule		p.P65P(1)		breast(2)|cervix(1)|endometrium(2)|kidney(2)|large_intestine(9)|lung(9)|ovary(2)|prostate(2)|skin(1)|upper_aerodigestive_tract(4)	34						TGCTCTCGTCCGGGCAGGTCT	0.612000													21	91					1.96895e-08	2.65261e-08	0.002780	1	0
NPY1R	4886	broad.mit.edu	37	4	164247318	164247318	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr4:164247318G>A	ENST00000296533.2	-	2	920	c.389C>T	c.(388-390)tCt>tTt	p.S130F	NPY1R_ENST00000509586.1_Intron	NM_000909.5	NP_000900.1	P25929	NPY1R_HUMAN	neuropeptide Y receptor Y1	130					inhibition of adenylate cyclase activity by G-protein signaling pathway|outflow tract morphogenesis	integral to plasma membrane	protein binding	p.S130F(1)		breast(1)|cervix(1)|large_intestine(4)|lung(18)|pancreas(1)|skin(1)|upper_aerodigestive_tract(4)	30	all_hematologic(180;0.166)	Prostate(90;0.0959)|all_neural(102;0.223)				GAGAACCAGAGAGAAAATGGA	0.423000													13	61					0	0	0.003163	0	0
ACHE	43	broad.mit.edu	37	7	100491461	100491461	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:100491461G>A	ENST00000302913.4	-	2	531	c.393C>T	c.(391-393)aaC>aaT	p.N131N	ACHE_ENST00000241069.5_Silent_p.N131N|ACHE_ENST00000428317.1_Silent_p.N131N|ACHE_ENST00000419336.2_Silent_p.N131N|ACHE_ENST00000412389.1_Silent_p.N131N|ACHE_ENST00000411582.1_Silent_p.N131N	NM_015831.2	NP_056646.1	P22303	ACES_HUMAN	acetylcholinesterase	131					acetylcholine catabolic process in synaptic cleft|amyloid precursor protein metabolic process|cell adhesion|cell proliferation|choline metabolic process|DNA replication|muscle organ development|neurotransmitter biosynthetic process|osteoblast development|positive regulation of protein secretion|regulation of axonogenesis|regulation of dendrite morphogenesis|response to wounding|synapse assembly	anchored to membrane|axon|basal lamina|cell junction|cell surface|dendrite|endoplasmic reticulum lumen|extracellular space|Golgi apparatus|neuromuscular junction|nucleus|perinuclear region of cytoplasm|postsynaptic membrane|presynaptic membrane|synaptic cleft	acetylcholine binding|acetylcholinesterase activity|beta-amyloid binding|carboxylesterase activity|cholinesterase activity|collagen binding|laminin-1 binding|protein homodimerization activity|serine hydrolase activity	p.N131N(2)		large_intestine(3)|lung(7)|skin(3)|urinary_tract(3)	16	Lung NSC(181;0.041)|all_lung(186;0.0581)				Ambenonium(DB01122)|Atropine(DB00572)|Choline(DB00122)|Decamethonium(DB01245)|Demecarium bromide(DB00944)|Donepezil(DB00843)|Edrophonium(DB01010)|Ephedrine(DB01364)|Galantamine(DB00674)|Gallamine Triethiodide(DB00483)|Isoflurophate(DB00677)|Neostigmine(DB01400)|Physostigmine(DB00981)|Pyridostigmine(DB00545)|Rivastigmine(DB00989)|Tacrine(DB00382)|Tubocurarine(DB01199)	GTGTCCACACGTTGAGGTACA	0.592000													5	140					0	0	0.001168	0	0
SPATA16	83893	broad.mit.edu	37	3	172835183	172835183	+	Silent	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr3:172835183A>G	ENST00000351008.3	-	2	522	c.339T>C	c.(337-339)ccT>ccC	p.P113P		NM_031955.5	NP_114161.3	Q9BXB7	SPT16_HUMAN	spermatogenesis associated 16	113					cell differentiation|multicellular organismal development|spermatogenesis	Golgi apparatus	binding	p.P113P(1)		breast(2)|cervix(1)|large_intestine(8)|lung(20)|ovary(2)|prostate(1)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(1)	43	Ovarian(172;0.00319)|Breast(254;0.197)		LUSC - Lung squamous cell carcinoma(14;1.48e-14)|Lung(28;6.63e-14)			AGGGGATGTGAGGCAGAGGCA	0.413000													3	131					0	0	0.004672	0	0
FRAS1	80144	broad.mit.edu	37	4	79410160	79410160	+	Missense_Mutation	SNP	G	G	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr4:79410160G>T	ENST00000264895.6	+	59	9324	c.8884G>T	c.(8884-8886)Gct>Tct	p.A2962S		NM_025074.6	NP_079350.5	Q86XX4	FRAS1_HUMAN	Fraser syndrome 1	2957	Calx-beta 4.				cell communication	integral to membrane|plasma membrane	metal ion binding	p.A2963S(1)|p.A2962S(1)		breast(2)|central_nervous_system(2)|cervix(2)|endometrium(14)|haematopoietic_and_lymphoid_tissue(2)|kidney(9)|large_intestine(5)|lung(54)|prostate(7)|skin(2)|urinary_tract(4)	103						GAGCCATTCCGCTCAGGTCAT	0.502000													10	50					7.48243e-07	9.80805e-07	0.006214	1	0
DAGLA	747	broad.mit.edu	37	11	61508792	61508792	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr11:61508792G>A	ENST00000257215.5	+	19	2258	c.2142G>A	c.(2140-2142)ccG>ccA	p.P714P		NM_006133.2	NP_006124.1	Q9Y4D2	DGLA_HUMAN	diacylglycerol lipase, alpha	714					cell death|lipid catabolic process|platelet activation	integral to membrane|plasma membrane	acylglycerol lipase activity|metal ion binding|triglyceride lipase activity	p.P714P(1)		breast(1)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(4)|liver(2)|lung(17)|ovary(2)|prostate(1)|skin(1)|upper_aerodigestive_tract(4)	43				READ - Rectum adenocarcinoma(4;0.219)		TGGAGCTGCCGACTGCAGACC	0.642000													9	30					0	0	0.008291	0	0
ARID3B	10620	broad.mit.edu	37	15	74883672	74883672	+	Silent	SNP	T	T	C			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr15:74883672T>C	ENST00000346246.5	+	6	1293	c.1062T>C	c.(1060-1062)ctT>ctC	p.L354L		NM_006465.2	NP_006456.1	Q8IVW6	ARI3B_HUMAN	AT rich interactive domain 3B (BRIGHT-like)	354	Interaction with RB1.				regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding	p.L354L(1)		NS(1)|breast(1)|endometrium(1)|large_intestine(2)|lung(7)|prostate(2)	14						CCCCTGCCCTTCTCTCCCCAC	0.647000													3	96					0	0	0.004672	0	0
CHRM2	1129	broad.mit.edu	37	7	136700046	136700046	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:136700046C>T	ENST00000445907.2	+	3	962	c.434C>T	c.(433-435)gCa>gTa	p.A145V	CHRM2_ENST00000401861.1_Missense_Mutation_p.A145V|CHRM2_ENST00000320658.5_Missense_Mutation_p.A145V|AC009264.1_ENST00000598184.1_RNA|AC009264.1_ENST00000439694.1_RNA|CHRM2_ENST00000453373.1_Missense_Mutation_p.A145V|CHRM2_ENST00000397608.3_Missense_Mutation_p.A145V|AC009264.1_ENST00000597642.1_RNA|AC009264.1_ENST00000425981.2_RNA|AC009264.1_ENST00000593789.1_RNA|AC009264.1_ENST00000592183.1_RNA|AC009264.1_ENST00000586239.1_RNA|CHRM2_ENST00000402486.3_Missense_Mutation_p.A145V	NM_001006627.1|NM_001006629.1	NP_001006628.1|NP_001006630.1	P08172	ACM2_HUMAN	cholinergic receptor, muscarinic 2	145					activation of phospholipase C activity by muscarinic acetylcholine receptor signaling pathway|G-protein signaling, coupled to cAMP nucleotide second messenger|nervous system development|regulation of heart contraction|response to virus	cell junction|integral to plasma membrane|postsynaptic membrane	muscarinic acetylcholine receptor activity|protein binding	p.A145V(1)		central_nervous_system(1)|cervix(1)|endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(13)|liver(1)|lung(29)|ovary(4)|pancreas(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(1)	68					Anisotropine Methylbromide(DB00517)|Atropine(DB00572)|Benzquinamide(DB00767)|Carbachol(DB00411)|Cryptenamine(DB00785)|Cyclizine(DB01176)|Desipramine(DB01151)|Diphenidol(DB01231)|Doxacurium chloride(DB01135)|Doxacurium(DB01334)|Flavoxate(DB01148)|Gallamine Triethiodide(DB00483)|Homatropine Methylbromide(DB00725)|Hyoscyamine(DB00424)|Ipratropium(DB00332)|Methotrimeprazine(DB01403)|Metixene(DB00340)|Metocurine(DB01336)|Mivacurium(DB01226)|Olanzapine(DB00334)|Oxybutynin(DB01062)|Oxyphencyclimine(DB00383)|Pilocarpine(DB01085)|Procyclidine(DB00387)|Promazine(DB00420)|Promethazine(DB01069)|Propiomazine(DB00777)|Rocuronium(DB00728)|Thiethylperazine(DB00372)|Tolterodine(DB01036)|Tridihexethyl(DB00505)|Triflupromazine(DB00508)	ATGATGATTGCAGCTGCCTGG	0.498000													5	173					0	0	0.001168	0	0
GRIN2A	2903	broad.mit.edu	37	16	9857312	9857312	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:9857312G>A	ENST00000396573.2	-	14	4398	c.4089C>T	c.(4087-4089)tcC>tcT	p.S1363S	GRIN2A_ENST00000404927.2_Intron|GRIN2A_ENST00000330684.3_Silent_p.S1363S|GRIN2A_ENST00000562109.1_Intron|GRIN2A_ENST00000535259.1_Intron|GRIN2A_ENST00000396575.2_Silent_p.S1363S	NM_000833.3	NP_000824.1	Q12879	NMDE1_HUMAN	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	1363					response to ethanol	cell junction|N-methyl-D-aspartate selective glutamate receptor complex|outer membrane-bounded periplasmic space|postsynaptic membrane	N-methyl-D-aspartate selective glutamate receptor activity|zinc ion binding	p.S1363S(1)		NS(7)|breast(5)|cervix(1)|endometrium(11)|kidney(6)|large_intestine(36)|lung(71)|ovary(4)|prostate(9)|skin(45)|upper_aerodigestive_tract(2)|urinary_tract(1)	198					Felbamate(DB00949)|Glycine(DB00145)|L-Glutamic Acid(DB00142)|Loperamide(DB00836)|Memantine(DB01043)	AAGGGTTATCGGAGGTGTGGT	0.557000													19	81					0	0	0.007413	0	0
CEBPZ	10153	broad.mit.edu	37	2	37454813	37454813	+	Missense_Mutation	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:37454813A>G	ENST00000234170.5	-	2	1668	c.1523T>C	c.(1522-1524)aTt>aCt	p.I508T		NM_005760.2	NP_005751.2	Q03701	CEBPZ_HUMAN	CCAAT/enhancer binding protein (C/EBP), zeta	508					regulation of transcription, DNA-dependent|transcription from RNA polymerase II promoter	nucleus	DNA binding	p.I508T(1)		breast(3)|endometrium(2)|large_intestine(7)|lung(12)|ovary(1)|pancreas(1)|prostate(1)|skin(1)	28		all_hematologic(82;0.21)				CAGTGTGTCAATCTGCTCCCT	0.378000													15	57					0	0	0.002450	0	0
GPATCH1	55094	broad.mit.edu	37	19	33584407	33584407	+	Missense_Mutation	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr19:33584407A>G	ENST00000170564.2	+	4	751	c.437A>G	c.(436-438)gAc>gGc	p.D146G		NM_018025.2	NP_060495.2	Q9BRR8	GPTC1_HUMAN	G patch domain containing 1	146						catalytic step 2 spliceosome	nucleic acid binding	p.D146G(1)		breast(4)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(7)|lung(15)|prostate(4)|skin(4)	40	Esophageal squamous(110;0.137)					CTCCTTGATGACCTCATAACG	0.478000													3	166					0	0	0.009096	0	0
TTN	7273	broad.mit.edu	37	2	179584290	179584290	+	Missense_Mutation	SNP	G	G	C			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:179584290G>C	ENST00000589042.1	-	82	24153	c.23929C>G	c.(23929-23931)Cat>Gat	p.H7977D	TTN_ENST00000591111.1_Missense_Mutation_p.H7660D|TTN-AS1_ENST00000585451.1_RNA|TTN_ENST00000460472.2_Intron|TTN_ENST00000359218.5_Intron|TTN_ENST00000342992.6_Missense_Mutation_p.H6733D|TTN_ENST00000342175.6_Intron	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	7660	Ig-like 62.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity	p.H6733D(1)		NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			CCAGAAACATGGACGGATACA	0.398000													28	254					0	0	0.007291	0	0
CDH10	1008	broad.mit.edu	37	5	24537504	24537504	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr5:24537504C>T	ENST00000264463.4	-	3	1018	c.511G>A	c.(511-513)Gaa>Aaa	p.E171K		NM_006727.3	NP_006718.2	Q9Y6N8	CAD10_HUMAN	cadherin 10, type 2 (T2-cadherin)	171	Cadherin 2.				adherens junction organization|cell junction assembly|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding	p.E171K(2)		NS(1)|breast(8)|central_nervous_system(2)|cervix(1)|endometrium(9)|kidney(2)|large_intestine(29)|lung(111)|ovary(6)|pancreas(6)|skin(4)|stomach(2)|upper_aerodigestive_tract(4)	185				STAD - Stomach adenocarcinoma(35;0.0556)		ACAGACATTTCGGGAACACTA	0.333000										HNSCC(23;0.051)			17	198					0	0	0.004990	0	0
ANK2	287	broad.mit.edu	37	4	114170985	114170985	+	Missense_Mutation	SNP	G	G	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr4:114170985G>T	ENST00000357077.4	+	10	1010	c.957G>T	c.(955-957)ttG>ttT	p.L319F	ANK2_ENST00000394537.3_Missense_Mutation_p.L319F|ANK2_ENST00000506722.1_Missense_Mutation_p.L298F|ANK2_ENST00000264366.6_Missense_Mutation_p.L319F	NM_001148.4	NP_001139.3	Q01484	ANK2_HUMAN	ankyrin 2, neuronal	319					axon guidance|signal transduction	apical plasma membrane|basolateral plasma membrane|cytoskeleton|cytosol|sarcomere	protein binding	p.L319F(1)		NS(1)|biliary_tract(1)|breast(9)|central_nervous_system(10)|cervix(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(7)|large_intestine(54)|liver(2)|lung(112)|ovary(8)|pancreas(1)|prostate(7)|skin(11)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(10)	248		Ovarian(17;0.0448)|Hepatocellular(203;0.218)		OV - Ovarian serous cystadenocarcinoma(123;4.92e-05)		AACTTCTGTTGGAACGGGGTG	0.453000													17	57					1.15919e-05	1.46027e-05	0.008871	1	0
DCDC1	341019	broad.mit.edu	37	11	31312327	31312327	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr11:31312327C>T	ENST00000597505.1	-	5	826	c.827G>A	c.(826-828)cGg>cAg	p.R276Q	DCDC1_ENST00000452803.1_Missense_Mutation_p.R276Q			P59894	DCDC1_HUMAN	doublecortin domain containing 1	276					intracellular signal transduction			p.R276Q(1)|p.R276L(1)		central_nervous_system(1)|cervix(1)|endometrium(1)|kidney(2)|large_intestine(4)|lung(17)|pancreas(2)|prostate(1)|skin(1)|stomach(1)	31	Lung SC(675;0.225)					CTTGGTTTTCCGTCTTTTGAT	0.378000													9	73					0	0	0.006214	0	0
NRXN2	9379	broad.mit.edu	37	11	64434911	64434911	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr11:64434911G>A	ENST00000265459.6	-	9	2070	c.1609C>T	c.(1609-1611)Cgg>Tgg	p.R537W	NRXN2_ENST00000377551.1_Missense_Mutation_p.R537W|NRXN2_ENST00000377559.3_Missense_Mutation_p.R506W|NRXN2_ENST00000409571.1_Missense_Mutation_p.R530W	NM_015080.3	NP_055895.1	Q9P2S2	NRX2A_HUMAN	neurexin 2	537	Laminin G-like 3.				cell adhesion	integral to membrane	metal ion binding	p.R537W(1)		breast(2)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(6)|liver(1)|lung(34)|ovary(6)|pancreas(1)|prostate(2)|skin(3)|upper_aerodigestive_tract(6)|urinary_tract(1)	71						CCCCCAGCCCGCCGGCCCTGG	0.657000													11	69					0	0	0.010729	0	0
SCN7A	6332	broad.mit.edu	37	2	167327178	167327178	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:167327178G>A	ENST00000409855.1	-	6	737	c.611C>T	c.(610-612)aCg>aTg	p.T204M		NM_002976.3	NP_002967.2	Q01118	SCN7A_HUMAN	sodium channel, voltage-gated, type VII, alpha subunit	204					muscle contraction	voltage-gated sodium channel complex	voltage-gated sodium channel activity	p.T204M(2)		breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(1)|lung(30)|prostate(4)|soft_tissue(1)|urinary_tract(1)	44						AGTTTGAAGCGTTGGAATGAA	0.299000													6	34					0	0	0.004482	0	0
AKAP9	10142	broad.mit.edu	37	7	91645514	91645514	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:91645514G>A	ENST00000359028.2	+	12	3945	c.3720G>A	c.(3718-3720)gaG>gaA	p.E1240E	AKAP9_ENST00000358100.2_Silent_p.E1240E|AKAP9_ENST00000356239.3_Silent_p.E1228E			Q99996	AKAP9_HUMAN	A kinase (PRKA) anchor protein 9	1240					G2/M transition of mitotic cell cycle|signal transduction|synaptic transmission|transport	centrosome|cytosol|Golgi apparatus	receptor binding	p.E1240E(1)|p.E1228E(1)		NS(1)|autonomic_ganglia(2)|breast(14)|central_nervous_system(3)|cervix(1)|endometrium(13)|kidney(12)|large_intestine(35)|lung(49)|ovary(8)|prostate(6)|skin(8)|stomach(1)|urinary_tract(2)	155	all_cancers(62;2.46e-09)|all_epithelial(64;4.42e-08)|Breast(17;0.00206)|all_lung(186;0.185)|all_hematologic(106;0.215)|Lung NSC(181;0.249)		STAD - Stomach adenocarcinoma(171;6.16e-05)|Lung(22;0.123)|LUSC - Lung squamous cell carcinoma(200;0.225)			AAGACAAAGAGAATTCTGGTG	0.294000			T	BRAF	papillary thyroid								6	51					0	0	0.001168	0	0
ADCY2	108	broad.mit.edu	37	5	7706887	7706887	+	Silent	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr5:7706887C>T	ENST00000338316.4	+	8	1229	c.1140C>T	c.(1138-1140)atC>atT	p.I380I	ADCY2_ENST00000537121.1_Silent_p.I200I	NM_020546.2	NP_065433.2	Q08462	ADCY2_HUMAN	adenylate cyclase 2 (brain)	380					activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	cytoplasm|dendrite|integral to membrane|plasma membrane	ATP binding|metal ion binding	p.I380I(1)		NS(3)|breast(2)|central_nervous_system(2)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(22)|lung(56)|ovary(8)|pancreas(1)|prostate(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(7)	119						GAGTTGATATCAACATGCGCG	0.463000													16	242					0	0	0.004990	0	0
CORO2A	7464	broad.mit.edu	37	9	100893269	100893269	+	Missense_Mutation	SNP	C	C	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr9:100893269C>G	ENST00000343933.5	-	7	1095	c.838G>C	c.(838-840)Gcg>Ccg	p.A280P	CORO2A_ENST00000375077.4_Missense_Mutation_p.A280P	NM_003389.3	NP_003380.3	Q92828	COR2A_HUMAN	coronin, actin binding protein, 2A	280					actin cytoskeleton organization|intracellular signal transduction	actin cytoskeleton|transcriptional repressor complex	actin filament binding	p.A280P(1)		endometrium(2)|kidney(2)|large_intestine(8)|lung(7)|ovary(1)|pancreas(1)|skin(4)|urinary_tract(1)	26		Acute lymphoblastic leukemia(62;0.0559)				CTGGTGTCCGCGTCATAGAAG	0.652000													3	26					0	0	0.009096	0	0
SLC22A2	6582	broad.mit.edu	37	6	160679385	160679385	+	Silent	SNP	G	G	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr6:160679385G>T	ENST00000366952.1	-	3	1823	c.342C>A	c.(340-342)atC>atA	p.I114I	SLC22A2_ENST00000491092.1_5'UTR|SLC22A2_ENST00000366953.3_Silent_p.I135I			O15244	S22A2_HUMAN	solute carrier family 22 (organic cation transporter), member 2	135					body fluid secretion|neurotransmitter biosynthetic process|neurotransmitter secretion	integral to plasma membrane|membrane fraction	neurotransmitter transporter activity|organic cation transmembrane transporter activity	p.I135I(1)		breast(2)|endometrium(3)|kidney(1)|large_intestine(2)|lung(16)|prostate(2)|skin(1)	27		Breast(66;0.000776)|Ovarian(120;0.0303)		OV - Ovarian serous cystadenocarcinoma(65;2.28e-17)|BRCA - Breast invasive adenocarcinoma(81;6.29e-06)		CCTCGGTGACGATGGACGAGC	0.617000													7	76					2.7689e-08	3.67922e-08	0.001984	1	0
ADAM19	8728	broad.mit.edu	37	5	156915310	156915310	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr5:156915310C>T	ENST00000257527.4	-	21	2591	c.2513G>A	c.(2512-2514)cGg>cAg	p.R838Q	ADAM19_ENST00000394020.1_Missense_Mutation_p.R840Q|ADAM19_ENST00000430702.2_Missense_Mutation_p.R571Q|ADAM19_ENST00000517905.1_Missense_Mutation_p.R838Q	NM_033274.3	NP_150377.1	Q9H013	ADA19_HUMAN	ADAM metallopeptidase domain 19	838					proteolysis	integral to membrane	metalloendopeptidase activity|SH3 domain binding|zinc ion binding	p.R838Q(1)|p.R839Q(1)		breast(1)|endometrium(2)|kidney(1)|large_intestine(6)|lung(33)|ovary(3)|pancreas(1)|prostate(1)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	53	Renal(175;0.00488)	Medulloblastoma(196;0.0359)|all_neural(177;0.14)	Kidney(164;0.000171)|KIRC - Kidney renal clear cell carcinoma(164;0.000785)			GGGAATTGGCCGGCTTGGAGG	0.572000													17	145					0	0	0.006122	0	0
SSNA1	8636	broad.mit.edu	37	9	140083651	140083651	+	Silent	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr9:140083651A>G	ENST00000322310.5	+	2	266	c.186A>G	c.(184-186)gcA>gcG	p.A62A	SSNA1_ENST00000459860.1_3'UTR	NM_003731.2	NP_003722.2	O43805	SSNA1_HUMAN	Sjogren syndrome nuclear autoantigen 1	62					G2/M transition of mitotic cell cycle	centrosome|cytosol|nucleus		p.A62A(1)		breast(2)|kidney(1)|large_intestine(1)|lung(2)	6	all_cancers(76;0.0926)		STAD - Stomach adenocarcinoma(284;0.0698)	OV - Ovarian serous cystadenocarcinoma(145;6.43e-05)|Epithelial(140;0.00087)		AGAACCTGGCACGCAAGATTG	0.647000													5	24					0	0	0.001168	0	0
SNX31	169166	broad.mit.edu	37	8	101612642	101612642	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr8:101612642C>T	ENST00000311812.2	-	9	859	c.709G>A	c.(709-711)Gcc>Acc	p.A237T	SNX31_ENST00000428383.2_Missense_Mutation_p.A138T	NM_152628.3	NP_689841.3	Q8N9S9	SNX31_HUMAN	sorting nexin 31	237					cell communication|protein transport		phosphatidylinositol binding			NS(1)|breast(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(12)|prostate(1)|skin(3)|urinary_tract(1)	26	all_cancers(14;4.01e-05)|all_epithelial(15;1.26e-07)|Lung NSC(17;0.000453)|all_lung(17;0.00125)		Epithelial(11;1.21e-11)|all cancers(13;2.62e-09)|OV - Ovarian serous cystadenocarcinoma(57;3.22e-06)|STAD - Stomach adenocarcinoma(118;0.206)			GTGGGTTTGGCCCATCCTTTT	0.363000													4	235					0	0	0.001168	0	0
LYST	1130	broad.mit.edu	37	1	235950598	235950598	+	Silent	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr1:235950598G>A	ENST00000389794.3	-	14	4938	c.4764C>T	c.(4762-4764)ctC>ctT	p.L1588L	LYST_ENST00000536965.1_3'UTR|LYST_ENST00000389793.2_Silent_p.L1588L			Q99698	LYST_HUMAN	lysosomal trafficking regulator	1588					defense response to bacterium|defense response to protozoan|defense response to virus|endosome to lysosome transport via multivesicular body sorting pathway|leukocyte chemotaxis|mast cell secretory granule organization|melanosome organization|natural killer cell mediated cytotoxicity|protein transport	cytoplasm|microtubule cytoskeleton	protein binding	p.L1588L(1)		NS(1)|breast(13)|central_nervous_system(3)|cervix(3)|endometrium(17)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(27)|lung(66)|ovary(7)|pancreas(1)|prostate(4)|skin(4)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	162	Ovarian(103;0.0634)|Breast(184;0.23)	all_cancers(173;0.00246)|Prostate(94;0.0771)|Acute lymphoblastic leukemia(190;0.228)	OV - Ovarian serous cystadenocarcinoma(106;0.000674)			ATTTGCTTGGGAGGAAAATAT	0.423000													45	148					0	0	0.013114	0	0
ADAMTS18	170692	broad.mit.edu	37	16	77398246	77398246	+	Missense_Mutation	SNP	G	G	C			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:77398246G>C	ENST00000282849.5	-	5	1229	c.811C>G	c.(811-813)Cta>Gta	p.L271V		NM_199355.2	NP_955387.1	Q8TE60	ATS18_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 18	271					proteolysis	proteinaceous extracellular matrix	metalloendopeptidase activity|zinc ion binding	p.L271V(1)		NS(1)|breast(5)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(9)|large_intestine(26)|lung(44)|ovary(2)|pancreas(1)|prostate(1)|skin(19)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	118						TCAAACCTTAGATAGGTGTCC	0.468000													4	78					0	0	0.009096	0	0
SALL1	6299	broad.mit.edu	37	16	51173150	51173150	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:51173150G>A	ENST00000440970.1	-	2	3123	c.2692C>T	c.(2692-2694)Cgg>Tgg	p.R898W	SALL1_ENST00000541611.1_Intron|SALL1_ENST00000251020.4_Missense_Mutation_p.R995W|SALL1_ENST00000566102.1_Intron	NM_001127892.1	NP_001121364.1	Q9NSC2	SALL1_HUMAN	spalt-like transcription factor 1	995					adrenal gland development|branching involved in ureteric bud morphogenesis|embryonic digestive tract development|embryonic digit morphogenesis|gonad development|histone deacetylation|inductive cell-cell signaling|mesenchymal to epithelial transition involved in metanephros morphogenesis|negative regulation of transcription from RNA polymerase II promoter|olfactory bulb interneuron differentiation|olfactory bulb mitral cell layer development|olfactory nerve development|outer ear morphogenesis|pituitary gland development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of Wnt receptor signaling pathway|ureteric bud invasion|ventricular septum development	chromocenter|cytoplasm|heterochromatin|nucleus	beta-catenin binding|DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.R995W(2)		NS(4)|breast(2)|central_nervous_system(2)|endometrium(3)|kidney(5)|large_intestine(25)|lung(61)|ovary(3)|prostate(6)|skin(12)|upper_aerodigestive_tract(3)	126		all_cancers(37;0.0322)	COAD - Colon adenocarcinoma(2;0.24)			AATTTACCCCGGTCTCTAAAA	0.433000													6	85					0	0	0.001168	0	0
FKBP2	2286	broad.mit.edu	37	11	64011314	64011314	+	Splice_Site	SNP	G	G	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr11:64011314G>T	ENST00000394540.3	+	5	803	c.331_splice	c.e5-1	p.G111_splice	FKBP2_ENST00000449942.2_Splice_Site_p.G111_splice|FKBP2_ENST00000309366.4_Splice_Site_p.G111_splice	NM_057092.2	NP_476433.1	P26885	FKBP2_HUMAN	FK506 binding protein 2, 13kDa	111	PPIase FKBP-type.				protein folding	endoplasmic reticulum membrane	FK506 binding|peptidyl-prolyl cis-trans isomerase activity|protein binding	p.G111G(1)		endometrium(2)|lung(3)	5						CTTCAACAGGGTATGGAGAGC	0.562000													32	134					3.86903e-22	5.43907e-22	0.013726	1	0
MED14	9282	broad.mit.edu	37	X	40569230	40569230	+	Splice_Site	SNP	C	C	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:40569230C>A	ENST00000324817.1	-	9	1292		c.e9+1			NM_004229.3	NP_004220.2	O60244	MED14_HUMAN	mediator complex subunit 14						androgen receptor signaling pathway|positive regulation of transcription from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter	mediator complex	ligand-dependent nuclear receptor transcription coactivator activity|receptor activity|RNA polymerase II transcription cofactor activity|thyroid hormone receptor binding|vitamin D receptor binding	p.?(1)		NS(2)|breast(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(4)|kidney(3)|large_intestine(7)|lung(8)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	39						AGATCTTTTACCTTCATGGCT	0.303000													13	33					0.000151284	0.000183432	0.001855	1	0
LOXL4	84171	broad.mit.edu	37	10	100011426	100011426	+	Missense_Mutation	SNP	C	C	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr10:100011426C>G	ENST00000260702.3	-	13	2135	c.1985G>C	c.(1984-1986)gGa>gCa	p.G662A		NM_032211.6	NP_115587.6	Q96JB6	LOXL4_HUMAN	lysyl oxidase-like 4	662	Lysyl-oxidase like.					extracellular space|membrane	copper ion binding|protein binding|scavenger receptor activity	p.G662A(1)		breast(1)|endometrium(6)|kidney(1)|large_intestine(3)|lung(8)|ovary(4)|prostate(1)|skin(2)	26		Colorectal(252;0.234)		Epithelial(162;2.14e-11)|all cancers(201;2.49e-09)		TCCCTGTTCTCCAAAGTTGGC	0.527000													3	56					0	0	0.004672	0	0
AR	367	broad.mit.edu	37	X	66931530	66931530	+	Splice_Site	SNP	T	T	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:66931530T>A	ENST00000374690.3	+	4	2696	c.2173_splice	c.e4+1	p.P724_splice	AR_ENST00000396044.3_Splice_Site_p.P724_splice|AR_ENST00000396043.2_Splice_Site_p.P192_splice	NM_000044.3	NP_000035.2	P10275	ANDR_HUMAN	androgen receptor	723	Interaction with MYST2.|Ligand-binding.		G -> D (in AIS and prostate cancer).		cell death|cell growth|cell proliferation|cell-cell signaling|negative regulation of apoptosis|negative regulation of integrin biosynthetic process|positive regulation of cell proliferation|positive regulation of integrin biosynthetic process|positive regulation of NF-kappaB transcription factor activity|positive regulation of phosphorylation|positive regulation of transcription from RNA polymerase II promoter|positive regulation of transcription from RNA polymerase III promoter|regulation of establishment of protein localization in plasma membrane|regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor|transport	cytoplasm|nuclear chromatin|nucleoplasm	androgen binding|androgen receptor activity|beta-catenin binding|enzyme binding|ligand-regulated transcription factor activity|protein dimerization activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|transcription regulatory region DNA binding|zinc ion binding	p.P534P(1)|p.P724P(1)		breast(4)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(1)|large_intestine(12)|lung(20)|ovary(3)|prostate(11)|stomach(2)|upper_aerodigestive_tract(3)	67	all_cancers(1;0.173)|Prostate(1;2.27e-16)|all_epithelial(1;0.102)	all_lung(315;1.3e-11)			Bicalutamide(DB01128)|Cyproterone(DB04839)|Dromostanolone(DB00858)|Finasteride(DB01216)|Fluoxymesterone(DB01185)|Flutamide(DB00499)|Nandrolone(DB00984)|Nilutamide(DB00665)|Oxandrolone(DB00621)|Testosterone(DB00624)	AGGCCTTGCCTGGTAAGGAAA	0.517000									Androgen Insensitivity Syndrome				11	71					0	0	0.013537	0	0
KCNV2	169522	broad.mit.edu	37	9	2719006	2719006	+	Missense_Mutation	SNP	T	T	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr9:2719006T>G	ENST00000382082.3	+	1	1505	c.1267T>G	c.(1267-1269)Ttc>Gtc	p.F423V		NM_133497.3	NP_598004.1	Q8TDN2	KCNV2_HUMAN	potassium channel, subfamily V, member 2	423						voltage-gated potassium channel complex	voltage-gated potassium channel activity	p.F423V(1)		NS(1)|breast(1)|central_nervous_system(3)|endometrium(5)|kidney(4)|large_intestine(7)|lung(9)|ovary(1)|prostate(2)|skin(2)	35				GBM - Glioblastoma multiforme(50;0.0257)		CATGGGCATCTTCACTTTCTC	0.632000													5	35					0	0	0.000602	0	0
OR1E1	8387	broad.mit.edu	37	17	3301440	3301440	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr17:3301440C>T	ENST00000322608.2	-	1	264	c.265G>A	c.(265-267)Gac>Aac	p.D89N		NM_003553.2	NP_003544.2	P30953	OR1E1_HUMAN	olfactory receptor, family 1, subfamily E, member 1	89					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.D89N(1)		endometrium(3)|large_intestine(2)|lung(5)	10						ATGGATGGGTCCTGGTTCTGC	0.507000													7	46					0	0	0.003080	0	0
SFMBT2	57713	broad.mit.edu	37	10	7409719	7409719	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr10:7409719C>T	ENST00000361972.4	-	4	418	c.328G>A	c.(328-330)Ggt>Agt	p.G110S	SFMBT2_ENST00000397160.3_Missense_Mutation_p.G110S|SFMBT2_ENST00000379711.2_Missense_Mutation_p.G110S|SFMBT2_ENST00000379713.3_Missense_Mutation_p.G110S|SFMBT2_ENST00000397167.1_Missense_Mutation_p.G110S	NM_001018039.1	NP_001018049.1	Q5VUG0	SMBT2_HUMAN	Scm-like with four mbt domains 2	110					regulation of transcription, DNA-dependent	nucleus		p.G110S(1)		NS(2)|breast(3)|central_nervous_system(4)|endometrium(7)|kidney(2)|large_intestine(26)|lung(34)|ovary(5)|pancreas(2)|skin(9)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	99						TCCCCGTAACCGCAGTAGCGC	0.572000													4	25					0	0	0.009096	0	0
F9	2158	broad.mit.edu	37	X	138630531	138630531	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:138630531G>A	ENST00000218099.2	+	5	408	c.401G>A	c.(400-402)tGt>tAt	p.C134Y	F9_ENST00000479617.1_3'UTR|F9_ENST00000394090.2_Missense_Mutation_p.C96Y	NM_000133.3	NP_000124.1	P00740	FA9_HUMAN	coagulation factor IX	134	EGF-like 2.		C -> Y (in HEMB).		blood coagulation, extrinsic pathway|blood coagulation, intrinsic pathway|peptidyl-glutamic acid carboxylation|post-translational protein modification|proteolysis	endoplasmic reticulum lumen|extracellular region|Golgi lumen|plasma membrane	calcium ion binding|serine-type endopeptidase activity	p.C134Y(1)		breast(1)|central_nervous_system(2)|endometrium(4)|large_intestine(7)|lung(19)|ovary(1)|skin(1)	35	Acute lymphoblastic leukemia(192;0.000127)				Antihemophilic Factor(DB00025)|Coagulation Factor IX(DB00100)|Heparin(DB01109)|Menadione(DB00170)	GATGTAACATGTAACATTAAG	0.363000													9	234					0	0	0.006214	0	0
ST6GAL2	84620	broad.mit.edu	37	2	107460326	107460326	+	Silent	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:107460326A>G	ENST00000409382.3	-	2	718	c.108T>C	c.(106-108)gcT>gcC	p.A36A	ST6GAL2_ENST00000361686.4_Silent_p.A36A|ST6GAL2_ENST00000409087.3_Silent_p.A36A	NM_001142351.1	NP_001135823.1	Q96JF0	SIAT2_HUMAN	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	36					growth|multicellular organismal development|oligosaccharide metabolic process|protein glycosylation	Golgi cisterna membrane|integral to Golgi membrane	beta-galactoside alpha-2,6-sialyltransferase activity	p.A36A(1)		autonomic_ganglia(1)|breast(1)|endometrium(2)|kidney(1)|large_intestine(8)|liver(1)|lung(30)|ovary(5)|pancreas(6)|prostate(2)|skin(4)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	65						GTACAGGCTCAGCGGGGTTGC	0.582000													4	65					0	0	0.000602	0	0
ST8SIA2	8128	broad.mit.edu	37	15	92981770	92981770	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr15:92981770G>A	ENST00000268164.3	+	4	715	c.478G>A	c.(478-480)Gtg>Atg	p.V160M	ST8SIA2_ENST00000539113.1_Missense_Mutation_p.V139M	NM_006011.3	NP_006002.1	Q92186	SIA8B_HUMAN	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	160					axon guidance|N-glycan processing|oligosaccharide biosynthetic process|post-translational protein modification|protein N-linked glycosylation via asparagine	integral to Golgi membrane	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	p.V160M(1)		endometrium(2)|large_intestine(6)|lung(9)|skin(2)|urinary_tract(1)	20	Lung NSC(78;0.0893)|all_lung(78;0.125)		BRCA - Breast invasive adenocarcinoma(143;0.0355)|OV - Ovarian serous cystadenocarcinoma(32;0.203)			TTGTGCCATCGTGGGCAACTC	0.582000													4	64					0	0	0.009096	0	0
CXADRP3	440224	broad.mit.edu	37	18	14479126	14479126	+	RNA	SNP	A	A	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr18:14479126A>T	ENST00000581457.1	-	0	782					NR_024076.1																						CCTGGTCTTCAGGACTAAGCG	0.418000													3	18					0	0	0.004672	0	0
DNAJC2	27000	broad.mit.edu	37	7	102956536	102956536	+	Splice_Site	SNP	C	C	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:102956536C>G	ENST00000379263.3	-	14	1678		c.e14-1		PMPCB_ENST00000420236.2_Intron|DNAJC2_ENST00000249270.7_Splice_Site	NM_014377.1	NP_055192.1	Q99543	DNJC2_HUMAN	DnaJ (Hsp40) homolog, subfamily C, member 2						'de novo' cotranslational protein folding|chromatin modification|positive regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytosol|nuclear membrane	chromatin binding|DNA binding|histone binding|Hsp70 protein binding|ubiquitin binding	p.?(2)		endometrium(1)|kidney(9)|large_intestine(6)|lung(4)|ovary(1)	21						AACTTCCCATCTGATAGGATA	0.308000													5	53					0	0	0.000602	0	0
ARSD	414	broad.mit.edu	37	X	2828021	2828021	+	Splice_Site	SNP	C	C	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:2828021C>G	ENST00000381154.1	-	8	1211		c.e8-1			NM_001669.3	NP_001660.2	P51689	ARSD_HUMAN	arylsulfatase D							lysosome	arylsulfatase activity|metal ion binding	p.?(1)		large_intestine(3)|lung(3)	6		all_cancers(21;4.28e-07)|all_epithelial(21;2.07e-08)|all_lung(23;2.81e-05)|Lung NSC(23;0.000693)|Lung SC(21;0.122)				CCCTTCCCACCTGTAAGTAGA	0.577000													19	60					0	0	0.008871	0	0
BASP1	10409	broad.mit.edu	37	5	17275411	17275411	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr5:17275411C>T	ENST00000322611.3	+	2	346	c.86C>T	c.(85-87)gCg>gTg	p.A29V		NM_001271606.1|NM_006317.3	NP_001258535.1|NP_006308.3	P80723	BASP1_HUMAN	brain abundant, membrane attached signal protein 1	29					glomerular visceral epithelial cell differentiation|negative regulation of transcription, DNA-dependent	cytoplasm|cytoskeleton|growth cone|nuclear speck|plasma membrane	protein domain specific binding|transcription corepressor activity|transcription regulatory region DNA binding	p.A29V(2)		endometrium(1)|lung(8)	9						GCCGAGGGCGCGGCGACGGAA	0.627000													4	58					0	0	0.009096	0	0
FAM120C	54954	broad.mit.edu	37	X	54209079	54209079	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chrX:54209079G>A	ENST00000375180.2	-	1	609	c.553C>T	c.(553-555)Cgt>Tgt	p.R185C	FAM120C_ENST00000477084.1_Missense_Mutation_p.R185C|FAM120C_ENST00000497680.1_5'UTR|FAM120C_ENST00000328235.4_Missense_Mutation_p.R185C	NM_017848.4	NP_060318.3	Q9NX05	F120C_HUMAN	family with sequence similarity 120C	185								p.R185C(1)		breast(3)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(5)|lung(9)|ovary(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	28						TGGCACCGACGGCCCCACTCG	0.716000													4	38					0	0	0.009096	0	0
RARS	5917	broad.mit.edu	37	5	167922429	167922429	+	Missense_Mutation	SNP	A	A	G			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr5:167922429A>G	ENST00000231572.3	+	6	743	c.689A>G	c.(688-690)tAt>tGt	p.Y230C	RARS_ENST00000538719.1_Missense_Mutation_p.Y24C	NM_002887.3	NP_002878.2	P54136	SYRC_HUMAN	arginyl-tRNA synthetase	230					arginyl-tRNA aminoacylation	cytosol|nucleus|soluble fraction	arginine-tRNA ligase activity|ATP binding|protein binding	p.Y230C(1)		breast(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(11)|ovary(2)|skin(1)|stomach(1)	22	Renal(175;0.000159)|Lung NSC(126;0.0875)|all_lung(126;0.166)	Medulloblastoma(196;0.0208)|all_neural(177;0.0227)	Kidney(164;7.53e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)	all cancers(165;0.0693)|Epithelial(171;0.131)|OV - Ovarian serous cystadenocarcinoma(192;0.156)		TTTGCAGGGTATGACGTGCTC	0.408000													7	168					0	0	0.001984	0	0
CDK5RAP2	55755	broad.mit.edu	37	9	123298731	123298731	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr9:123298731C>T	ENST00000349780.4	-	7	760	c.581G>A	c.(580-582)cGt>cAt	p.R194H	CDK5RAP2_ENST00000359309.3_Missense_Mutation_p.R194H|CDK5RAP2_ENST00000360822.3_Missense_Mutation_p.R194H|CDK5RAP2_ENST00000360190.4_Missense_Mutation_p.R194H	NM_018249.4	NP_060719.4	Q96SN8	CK5P2_HUMAN	CDK5 regulatory subunit associated protein 2	194					brain development|centrosome organization|chromosome segregation|G2/M transition of mitotic cell cycle|microtubule bundle formation|negative regulation of centriole replication|positive regulation of transcription, DNA-dependent|regulation of neuron differentiation|regulation of spindle checkpoint	cytosol|Golgi apparatus|microtubule|pericentriolar material|perinuclear region of cytoplasm|spindle pole	calmodulin binding|microtubule binding|neuronal Cdc2-like kinase binding|transcription regulatory region DNA binding	p.R194H(1)		breast(6)|central_nervous_system(1)|endometrium(3)|kidney(4)|large_intestine(12)|lung(21)|ovary(2)|prostate(2)|skin(6)|urinary_tract(1)	58						GCTTTCCAAACGCAACCGAAG	0.517000													8	65					0	0	0.003080	0	0
SALL1	6299	broad.mit.edu	37	16	51171227	51171227	+	Silent	SNP	G	G	A	rs145423593		TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr16:51171227G>A	ENST00000440970.1	-	3	3911	c.3480C>T	c.(3478-3480)aaC>aaT	p.N1160N	SALL1_ENST00000541611.1_Silent_p.N80N|SALL1_ENST00000251020.4_Silent_p.N1257N|SALL1_ENST00000566102.1_3'UTR	NM_001127892.1	NP_001121364.1	Q9NSC2	SALL1_HUMAN	spalt-like transcription factor 1	1257					adrenal gland development|branching involved in ureteric bud morphogenesis|embryonic digestive tract development|embryonic digit morphogenesis|gonad development|histone deacetylation|inductive cell-cell signaling|mesenchymal to epithelial transition involved in metanephros morphogenesis|negative regulation of transcription from RNA polymerase II promoter|olfactory bulb interneuron differentiation|olfactory bulb mitral cell layer development|olfactory nerve development|outer ear morphogenesis|pituitary gland development|positive regulation of transcription from RNA polymerase II promoter|positive regulation of Wnt receptor signaling pathway|ureteric bud invasion|ventricular septum development	chromocenter|cytoplasm|heterochromatin|nucleus	beta-catenin binding|DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding	p.N1257N(1)		NS(4)|breast(2)|central_nervous_system(2)|endometrium(3)|kidney(5)|large_intestine(25)|lung(61)|ovary(3)|prostate(6)|skin(12)|upper_aerodigestive_tract(3)	126		all_cancers(37;0.0322)	COAD - Colon adenocarcinoma(2;0.24)			GGATGCCACCGTTCTGAATGA	0.577000													6	87					0	0	0.003080	0	0
GRHL1	29841	broad.mit.edu	37	2	10130834	10130834	+	Missense_Mutation	SNP	G	G	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:10130834G>A	ENST00000324907.9	+	10	1416	c.1280G>A	c.(1279-1281)cGg>cAg	p.R427Q	GRHL1_ENST00000324883.5_Missense_Mutation_p.R238Q|GRHL1_ENST00000405379.2_Missense_Mutation_p.R427Q	NM_198182.2	NP_937825.2	Q9NZI5	GRHL1_HUMAN	grainyhead-like 1 (Drosophila)	427					cellular lipid metabolic process|multicellular organismal development|regulation of transcription, DNA-dependent|transcription, DNA-dependent	Golgi apparatus|nucleus	DNA binding	p.R427Q(1)|p.R238Q(1)		cervix(1)|endometrium(1)|large_intestine(2)|lung(8)|ovary(1)|pancreas(1)|skin(1)|stomach(1)|urinary_tract(1)	17	all_hematologic(175;0.127)|Acute lymphoblastic leukemia(172;0.155)			Epithelial(75;0.172)|OV - Ovarian serous cystadenocarcinoma(76;0.246)		GGAGCTGAGCGGAAAATCAGG	0.423000													6	18					0	0	0.001168	0	0
NT5C1B	93034	broad.mit.edu	37	2	18766072	18766072	+	Missense_Mutation	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr2:18766072C>T	ENST00000304081.4	-	4	531	c.431G>A	c.(430-432)cGg>cAg	p.R144Q	NT5C1B_ENST00000600945.1_Missense_Mutation_p.R204Q|NT5C1B-RDH14_ENST00000532967.1_Missense_Mutation_p.R204Q|NT5C1B_ENST00000359846.2_Missense_Mutation_p.R204Q	NM_033253.3	NP_150278.2			5'-nucleotidase, cytosolic IB									p.R204Q(1)		endometrium(2)|kidney(2)|large_intestine(10)|lung(8)|ovary(1)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(1)	29	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.177)	Ovarian(717;0.208)				GGTGCTGCGCCGGGAGCCAGG	0.711000													8	27					0	0	0.004482	0	0
SDK2	54549	broad.mit.edu	37	17	71346817	71346817	+	Missense_Mutation	SNP	G	G	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr17:71346817G>T	ENST00000392650.3	-	42	5871	c.5871C>A	c.(5869-5871)agC>agA	p.S1957R	SDK2_ENST00000410094.1_5'UTR|SDK2_ENST00000388726.3_Missense_Mutation_p.S1938R	NM_001144952.1	NP_001138424.1	Q58EX2	SDK2_HUMAN	sidekick cell adhesion molecule 2	1957					cell adhesion	integral to membrane		p.S1957R(1)		breast(4)|central_nervous_system(2)|cervix(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(15)|lung(31)|ovary(3)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	86						CGTACTTCTTGCTCTGGCCCC	0.547000													11	48					2.80697e-09	3.83488e-09	0.010729	1	0
ASB17	127247	broad.mit.edu	37	1	76397748	76397748	+	Missense_Mutation	SNP	A	A	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr1:76397748A>T	ENST00000284142.6	-	1	368	c.229T>A	c.(229-231)Tca>Aca	p.S77T		NM_080868.2	NP_543144.1	Q8WXJ9	ASB17_HUMAN	ankyrin repeat and SOCS box containing 17	77					intracellular signal transduction			p.S77T(1)		breast(1)|central_nervous_system(1)|endometrium(2)|large_intestine(3)|lung(11)|ovary(2)|urinary_tract(1)	21						CGGTATCCTGATTTTTCCACA	0.383000													27	71					0	0	0.003954	0	0
EPS15L1	58513	broad.mit.edu	37	19	16548580	16548580	+	Splice_Site	SNP	C	C	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr19:16548580C>T	ENST00000597937.1	-	5	314		c.e5+1		EPS15L1_ENST00000248070.6_Splice_Site|EPS15L1_ENST00000455140.2_Splice_Site|EPS15L1_ENST00000594975.1_Splice_Site|EPS15L1_ENST00000535753.2_Splice_Site	NM_001258376.1	NP_001245305.1	Q9UBC2	EP15R_HUMAN	epidermal growth factor receptor pathway substrate 15-like 1						endocytosis|epidermal growth factor receptor signaling pathway|negative regulation of epidermal growth factor receptor signaling pathway	coated pit|nucleus|plasma membrane	calcium ion binding	p.?(1)		breast(2)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(3)|large_intestine(3)|lung(12)|ovary(4)|skin(2)	30						TGGACACTCACAAATTTAGGC	0.443000													13	57					0	0	0.003163	0	0
SRGAP2-AS1	100873165	broad.mit.edu	37	1	121116645	121116645	+	RNA	DEL	T	T	-			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr1:121116645delT	ENST00000437515.1	-	0	329																											CAAGCCCCCCTTTAAAAAAAA	0.393													7	67	---	---	---	---					
UBA3	9039	broad.mit.edu	37	3	69129290	69129292	+	In_Frame_Del	DEL	CTT	CTT	-			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr3:69129290_69129292delCTT	ENST00000361055.4	-	2	87_89	c.33_35delAAG	c.(31-36)agg>ag	p.RR11del	UBA3_ENST00000540295.1_Intron|UBA3_ENST00000349511.4_Intron|UBA3_ENST00000415609.2_Intron	NM_003968.3	NP_003959.3	Q8TBC4	UBA3_HUMAN	ubiquitin-like modifier activating enzyme 3	11					protein neddylation|proteolysis	nucleus	acid-amino acid ligase activity|ATP binding|protein heterodimerization activity			endometrium(1)|kidney(1)|large_intestine(4)|lung(9)|ovary(1)|skin(1)|upper_aerodigestive_tract(2)	19		Lung NSC(201;0.0193)|Prostate(884;0.174)		BRCA - Breast invasive adenocarcinoma(55;7.98e-05)|Epithelial(33;0.000363)|LUSC - Lung squamous cell carcinoma(21;0.012)|Lung(16;0.0191)|KIRC - Kidney renal clear cell carcinoma(39;0.206)|Kidney(39;0.241)		CTCTATTCTCCTTCTTTTCTTCT	0.665													18	57	---	---	---	---					
ZNRD1-AS1	80862	broad.mit.edu	37	6	29970905	29970906	+	RNA	INS	-	-	G	rs139061936	by1000genomes	TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr6:29970905_29970906insG	ENST00000376797.3	-	0	1548				ZNRD1-AS1_ENST00000420251.1_RNA|ZNRD1-AS1_ENST00000425604.1_RNA|ZNRD1-AS1_ENST00000448093.1_RNA																							gctgaggccctcttcccatggg	0.545													4	3	---	---	---	---					
ZNF318	24149	broad.mit.edu	37	6	43305942	43305954	+	Frame_Shift_Del	DEL	TTCTAGAAGCTGA	TTCTAGAAGCTGA	-			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr6:43305942_43305954delTTCTAGAAGCTGA	ENST00000361428.2	-	10	5859_5871	c.5782_5794delTCAGCTTCTAGAA	c.(5782-5796)ctfs	p.SASRT1928fs	ZNF318_ENST00000318149.3_Intron	NM_014345.2	NP_055160.2	Q5VUA4	ZN318_HUMAN	zinc finger protein 318	1928					meiosis|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	nucleic acid binding|zinc ion binding			autonomic_ganglia(1)|breast(8)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|lung(21)|ovary(3)|prostate(1)|skin(1)|stomach(1)|urinary_tract(1)	61			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.0171)|OV - Ovarian serous cystadenocarcinoma(102;0.0579)			TACCTAGAAGTTCTAGAAGCTGATTCTGGAGCT	0.413													27	138	---	---	---	---					
CCT6P3	643180	broad.mit.edu	37	7	64528813	64528814	+	RNA	INS	-	-	T			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:64528813_64528814insT	ENST00000426828.1	+	0	621					NR_033416.1																						CTTTCTGTAACTTTTTTTTTTT	0.317													7	18	---	---	---	---					
GS1-124K5.2	0	broad.mit.edu	37	7	65888988	65888989	+	RNA	DEL	TT	TT	-	rs75924435		TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:65888988_65888989delTT	ENST00000442578.1	-	0	826																											tttttttttctttttttttttt	0.485													2	4	---	---	---	---					
CTAGE6	340307	broad.mit.edu	37	7	143453350	143453353	+	Frame_Shift_Del	DEL	CCAA	CCAA	-			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr7:143453350_143453353delCCAA	ENST00000470691.2	-	1	1436_1439	c.1399_1402delTTGG	c.(1399-1404)cafs	p.LA467fs		NM_178561.4	NP_848656.2			CTAGE family, member 6													Melanoma(164;0.0903)					GTCCGAGCTGCCAACCAATTATCA	0.348													13	172	---	---	---	---					
GLIPR1	11010	broad.mit.edu	37	12	75884200	75884201	+	Frame_Shift_Ins	INS	-	-	A			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr12:75884200_75884201insA	ENST00000266659.3	+	3	636_637	c.435_436insA	c.(433-438)gagttafs	p.L146fs		NM_006851.2	NP_006842.2	P48060	GLIP1_HUMAN	GLI pathogenesis-related 1	146					cellular lipid metabolic process	extracellular region|integral to membrane				endometrium(1)|kidney(2)|large_intestine(3)|lung(6)|ovary(1)|skin(1)	14						TTTGGGCAGATAGTTACAAAGT	0.386													14	104	---	---	---	---					
CSPG4P5	114817	broad.mit.edu	37	15	84958415	84958426	+	RNA	DEL	CGAGGACATTGG	CGAGGACATTGG	-			TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr15:84958415_84958426delCGAGGACATTGG	ENST00000558801.1	-	0	6303_6314																											TCGGGCACCACGAGGACATTGGTGAGGACAGG	0.557													4	7	---	---	---	---					
DNM1P47	100216544	broad.mit.edu	37	15	102293062	102293064	+	RNA	DEL	CTC	CTC	-	rs4965539		TCGA-49-4512-01A-21D-1855-08	TCGA-49-4512-11A-01D-1855-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	fa6a60f5-8949-4e01-9435-d3117601627f	f76ef845-8a03-4b61-b1b2-3f0b4ae5a759	g.chr15:102293062_102293064delCTC	ENST00000561463.1	+	0	1108_1110																											AGTTCATCTTCTCAGAGCTGCTG	0.576													2	4	---	---	---	---