Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
HLA-DRA	3122	broad.mit.edu	37	6	32411098	32411098	+	Silent	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:32411098A>T	ENST00000395388.2	+	3	574	c.465A>T	c.(463-465)acA>acT	p.T155T	HLA-DRA_ENST00000374982.5_Silent_p.T130T	NM_019111.4	NP_061984.2	P01903	DRA_HUMAN	major histocompatibility complex, class II, DR alpha	155	Alpha-2.|Ig-like C1-type.				antigen processing and presentation of peptide or polysaccharide antigen via MHC class II|interferon-gamma-mediated signaling pathway|T cell costimulation|T cell receptor signaling pathway	endoplasmic reticulum membrane|Golgi apparatus|integral to plasma membrane|late endosome membrane|lysosomal membrane|MHC class II protein complex	MHC class II receptor activity			NS(1)|breast(1)|large_intestine(6)|lung(5)|ovary(1)|skin(4)|upper_aerodigestive_tract(1)	19						CTGTCACCACAGGAGTGTCAG	0.522000									T-cell Lymphoma, (Cutaneous) , Familial Clustering of;Kaposi Sarcoma, Familial Clustering of				12	77					0	0	0.016723	0	0
PCNXL2	80003	broad.mit.edu	37	1	233296031	233296031	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:233296031C>G	ENST00000258229.8	-	19	3749	c.3515G>C	c.(3514-3516)aGa>aCa	p.R1172T	PCNXL2_ENST00000520463.1_5'UTR|PCNXL2_ENST00000488780.2_Missense_Mutation_p.R305T	NM_014801.3	NP_055616.3	A6NKB5	PCX2_HUMAN	pecanex-like 2 (Drosophila)	1172						integral to membrane				NS(1)|autonomic_ganglia(1)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(16)|kidney(7)|large_intestine(19)|lung(30)|pancreas(1)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	86		all_cancers(173;0.0347)|Prostate(94;0.137)				TTACTAACCTCTCACTTCCCG	0.413000													11	24					0	0	0.008291	0	0
OR2T8	343172	broad.mit.edu	37	1	248084349	248084349	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:248084349C>T	ENST00000319968.4	+	1	30	c.30C>T	c.(28-30)ttC>ttT	p.F10F		NM_001005522.1	NP_001005522.1	A6NH00	OR2T8_HUMAN	olfactory receptor, family 2, subfamily T, member 8	10					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(6)|lung(20)|pancreas(1)|prostate(1)|upper_aerodigestive_tract(1)	34	all_cancers(71;0.000139)|all_epithelial(71;1.58e-05)|Breast(184;0.0117)|Ovarian(71;0.0377)|all_lung(81;0.127)|Lung NSC(105;0.136)	all_cancers(173;0.0211)	OV - Ovarian serous cystadenocarcinoma(106;0.0319)			CCTCTTATTTCATTCTCCTAG	0.413000													10	87					0	0	0.006214	0	0
ARHGAP31	57514	broad.mit.edu	37	3	119133503	119133503	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:119133503G>T	ENST00000264245.4	+	12	3259	c.2727G>T	c.(2725-2727)gaG>gaT	p.E909D		NM_020754.2	NP_065805.2	Q2M1Z3	RHG31_HUMAN	Rho GTPase activating protein 31	909					regulation of small GTPase mediated signal transduction|small GTPase mediated signal transduction	cytosol|focal adhesion|lamellipodium	GTPase activator activity			breast(5)|central_nervous_system(1)|cervix(1)|endometrium(10)|kidney(3)|large_intestine(11)|lung(29)|ovary(2)|pancreas(1)|prostate(1)|skin(1)|stomach(1)|urinary_tract(1)	67						AGCCCTGGGAGGAACCCCAGT	0.582000													43	370					1.15505e-17	1.64061e-17	0.009718	1	0
PHKG2	5261	broad.mit.edu	37	16	30768220	30768220	+	Silent	SNP	T	T	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:30768220T>C	ENST00000563588.1	+	10	1262	c.1023T>C	c.(1021-1023)taT>taC	p.Y341Y	PHKG2_ENST00000328273.7_Silent_p.Y345Y|PHKG2_ENST00000424889.3_Silent_p.Y341Y	NM_000294.2	NP_000285.1	P15735	PHKG2_HUMAN	phosphorylase kinase, gamma 2 (testis)	341					glucose metabolic process|glycogen biosynthetic process|glycogen catabolic process	cytosol	ATP binding|calmodulin binding|phosphorylase kinase activity			ovary(1)|skin(1)	2			Colorectal(24;0.198)			GGGACCCTTATGCGCTGCGGT	0.612000													4	76					0	0	0.014758	0	0
SF3A1	10291	broad.mit.edu	37	22	30741134	30741134	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:30741134G>A	ENST00000215793.7	-	4	593	c.439C>T	c.(439-441)Cct>Tct	p.P147S	SF3A1_ENST00000439242.1_Intron	NM_005877.4	NP_005868.1	Q15459	SF3A1_HUMAN	splicing factor 3a, subunit 1, 120kDa	147					nuclear mRNA 3'-splice site recognition	catalytic step 2 spliceosome|nucleoplasm|U2-type spliceosomal complex	protein binding|RNA binding			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(9)|ovary(4)|pancreas(1)|prostate(1)|urinary_tract(1)	29						AACTCAGGAGGAGGCTCTTTG	0.552000													7	97					0	0	0.003080	0	0
ZNF717	100131827	broad.mit.edu	37	3	75790798	75790798	+	Translation_Start_Site	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:75790798G>A	ENST00000478296.1	-	0	273				ZNF717_ENST00000477374.1_Silent_p.D49D|ZNF717_ENST00000422325.1_Silent_p.D49D|ZNF717_ENST00000491507.1_5'UTR|ZNF717_ENST00000400845.3_Silent_p.D42D			C9JSV9	C9JSV9_HUMAN	zinc finger protein 717						regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding			autonomic_ganglia(6)|endometrium(3)|lung(2)|ovary(1)|stomach(7)	19						CCAGCATCACGTCCCTGTACA	0.502000													3	14					0	0	0.004672	0	0
TTF2	8458	broad.mit.edu	37	1	117618261	117618261	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:117618261A>G	ENST00000369466.3	+	5	1099	c.1055A>G	c.(1054-1056)gAc>gGc	p.D352G		NM_003594.3	NP_003585.3	Q9UNY4	TTF2_HUMAN	transcription termination factor, RNA polymerase II	352					mRNA processing|regulation of transcription, DNA-dependent|RNA splicing|termination of RNA polymerase II transcription	cytoplasm|spliceosomal complex|transcription elongation factor complex	ATP binding|ATP-dependent helicase activity|DNA binding|DNA-dependent ATPase activity|protein binding|zinc ion binding			NS(1)|autonomic_ganglia(1)|breast(1)|cervix(2)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|liver(1)|lung(24)|ovary(1)|prostate(2)|skin(2)|urinary_tract(2)	50	Lung SC(450;0.225)	all_cancers(81;4.23e-06)|all_epithelial(167;3.65e-07)|all_lung(203;2.81e-06)|Lung NSC(69;1.98e-05)		Lung(183;0.0553)|Colorectal(144;0.179)|LUSC - Lung squamous cell carcinoma(189;0.19)		ACAAGCAGTGACGACGAGGAG	0.572000													3	28					0	0	0.009096	0	0
PPM1H	57460	broad.mit.edu	37	12	63042360	63042360	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:63042360C>A	ENST00000228705.6	-	10	1754	c.1454G>T	c.(1453-1455)aGa>aTa	p.R485I	PPM1H_ENST00000551214.1_5'UTR	NM_020700.1	NP_065751.1	Q9ULR3	PPM1H_HUMAN	protein phosphatase, Mg2+/Mn2+ dependent, 1H	485	PP2C-like.						phosphoprotein phosphatase activity			breast(1)|endometrium(2)|kidney(1)|large_intestine(4)|lung(9)|ovary(1)	18			GBM - Glioblastoma multiforme(1;0.000443)|BRCA - Breast invasive adenocarcinoma(9;0.209)	GBM - Glioblastoma multiforme(28;0.0126)		CCGCCATCCTCTGTCCTTCAG	0.507000													5	51					3.09899e-07	4.13817e-07	0.004482	1	0
KIAA1211	57482	broad.mit.edu	37	4	57182258	57182258	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:57182258G>C	ENST00000504228.1	+	6	2695	c.2590G>C	c.(2590-2592)Gca>Cca	p.A864P	KIAA1211_ENST00000264229.6_Missense_Mutation_p.A864P|KIAA1211_ENST00000541073.1_Missense_Mutation_p.A857P			Q6ZU35	K1211_HUMAN	KIAA1211	864										endometrium(7)|large_intestine(10)|lung(39)|ovary(2)|prostate(3)|skin(3)|stomach(1)	65	Glioma(25;0.08)|all_neural(26;0.101)					CGACCAACAGGCAGAACAGAA	0.567000													6	87					0	0	0.001984	0	0
HS3ST5	222537	broad.mit.edu	37	6	114383995	114383995	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:114383995C>A	ENST00000312719.5	-	4	1203	c.15G>T	c.(13-15)caG>caT	p.Q5H	RP3-399L15.3_ENST00000523087.1_RNA|HS3ST5_ENST00000411826.1_Missense_Mutation_p.Q5H|RP3-399L15.3_ENST00000519104.1_RNA			Q8IZT8	HS3S5_HUMAN	heparan sulfate (glucosamine) 3-O-sulfotransferase 5	5					heparan sulfate proteoglycan biosynthetic process, enzymatic modification|negative regulation of coagulation|protein sulfation|regulation of virion penetration into host cell	Golgi membrane|integral to membrane	3'-phosphoadenosine 5'-phosphosulfate binding|[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity|protein binding			breast(4)|endometrium(2)|kidney(1)|large_intestine(7)|lung(17)|ovary(1)|pancreas(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(3)	41		all_cancers(87;0.0587)|Colorectal(196;0.0676)|all_epithelial(87;0.154)		OV - Ovarian serous cystadenocarcinoma(136;0.00937)|all cancers(137;0.0117)|Epithelial(106;0.0274)|GBM - Glioblastoma multiforme(226;0.143)		GCCACGCCTGCTGTTTGAATA	0.557000													8	78					2.17888e-05	2.66972e-05	0.006214	1	0
ATP8B4	79895	broad.mit.edu	37	15	50154509	50154509	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:50154509G>A	ENST00000284509.6	-	27	3371	c.3230C>T	c.(3229-3231)gCt>gTt	p.A1077V	ATP8B4_ENST00000559829.1_Missense_Mutation_p.A1077V	NM_024837.2	NP_079113.2	Q8TF62	AT8B4_HUMAN	ATPase, class I, type 8B, member 4	1077					ATP biosynthetic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			breast(6)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(14)|lung(27)|ovary(2)|pancreas(1)|prostate(1)|skin(7)|urinary_tract(1)	73		all_lung(180;0.00183)		all cancers(107;2.41e-07)|GBM - Glioblastoma multiforme(94;8.28e-05)		CATAACTGAAGCCACTGTTGT	0.413000													7	30					0	0	0.001984	0	0
DNMT3B	1789	broad.mit.edu	37	20	31376692	31376692	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:31376692G>T	ENST00000328111.2	+	7	1008	c.687G>T	c.(685-687)gtG>gtT	p.V229V	DNMT3B_ENST00000353855.2_Silent_p.V229V|DNMT3B_ENST00000344505.4_Silent_p.V229V|DNMT3B_ENST00000201963.3_Silent_p.V241V|DNMT3B_ENST00000456297.2_Silent_p.V153V|DNMT3B_ENST00000348286.2_Silent_p.V229V|DNMT3B_ENST00000443239.3_Silent_p.V187V|DNMT3B_ENST00000375623.4_Silent_p.V187V	NM_006892.3	NP_008823.1	Q9UBC3	DNM3B_HUMAN	DNA (cytosine-5-)-methyltransferase 3 beta	229	Interaction with DNMT1 and DNMT3A.|PWWP.				negative regulation of histone H3-K9 methylation|positive regulation of gene expression|positive regulation of histone H3-K4 methylation		metal ion binding|protein binding|transcription corepressor activity			endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(10)|lung(16)|ovary(3)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	39						GGGACCTCGTGTGGGGAAAGA	0.577000													7	64					0.00448238	0.00492399	0.004482	1	0
POLR2C	5432	broad.mit.edu	37	16	57503186	57503186	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:57503186A>G	ENST00000219252.5	+	5	706	c.368A>G	c.(367-369)aAc>aGc	p.N123S	POLR2C_ENST00000564651.1_3'UTR	NM_032940.2	NP_116558.1	P19387	RPB3_HUMAN	polymerase (RNA) II (DNA directed) polypeptide C, 33kDa	123					mRNA capping|nuclear mRNA splicing, via spliceosome|positive regulation of viral transcription|protein phosphorylation|transcription elongation from RNA polymerase II promoter|transcription initiation from RNA polymerase II promoter|transcription-coupled nucleotide-excision repair|viral reproduction	DNA-directed RNA polymerase II, core complex	DNA binding|DNA-directed RNA polymerase activity|protein dimerization activity			breast(1)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|lung(2)|upper_aerodigestive_tract(1)	10						CTCATCTCCAACAGCCCCCGG	0.587000													9	70					0	0	0.010729	0	0
NPIPA5	100288332	broad.mit.edu	37	16	15457676	15457676	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:15457676A>G	ENST00000360151.4	-	8	892	c.893T>C	c.(892-894)cTa>cCa	p.L298P		NM_001277325.1	NP_001264254.1			nuclear pore complex interacting protein family, member A5																		CGCTGAGGGTAGAGCTGAGGG	0.562000													4	120					0	0	0.001984	0	0
LCK	3932	broad.mit.edu	37	1	32745227	32745227	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:32745227C>A	ENST00000333070.4	+	10	1110	c.1010C>A	c.(1009-1011)tCc>tAc	p.S337Y	LCK_ENST00000373564.3_Intron|LCK_ENST00000336890.5_Intron	NM_001042771.1	NP_001036236.1	P06239	LCK_HUMAN	lymphocyte-specific protein tyrosine kinase	321	Protein kinase.				activation of caspase activity|cellular zinc ion homeostasis|induction of apoptosis|interspecies interaction between organisms|leukocyte migration|platelet activation|positive regulation of T cell receptor signaling pathway|regulation of defense response to virus by virus|release of sequestered calcium ion into cytosol|response to drug|T cell costimulation|T cell differentiation|T cell receptor signaling pathway|viral reproduction	cytosol|Golgi apparatus|membrane raft|pericentriolar material|plasma membrane	ATP binding|ATPase binding|CD4 receptor binding|CD8 receptor binding|glycoprotein binding|non-membrane spanning protein tyrosine kinase activity|phosphatidylinositol 3-kinase binding|protein C-terminus binding|protein kinase binding|protein serine/threonine phosphatase activity|SH2 domain binding			breast(2)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(5)|kidney(1)|large_intestine(5)|lung(15)|ovary(2)|skin(2)|urinary_tract(1)	37		Myeloproliferative disorder(586;0.0255)|all_neural(195;0.0837)|Ovarian(437;0.101)|Breast(348;0.212)			Dasatinib(DB01254)	CTGGGGGCCTCCCCCTGGGGC	0.517000			T	TRB@	T-ALL								5	73					8.12818e-05	9.64141e-05	0.001984	1	0
RAD51	5888	broad.mit.edu	37	15	41011072	41011072	+	Missense_Mutation	SNP	G	G	C	rs77029343		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:41011072G>C	ENST00000267868.3	+	6	773	c.505G>C	c.(505-507)Gaa>Caa	p.E169Q	RAD51_ENST00000557850.1_Intron|RAD51_ENST00000382643.3_Missense_Mutation_p.E170Q|RAD51_ENST00000532743.1_Missense_Mutation_p.E170Q|RAD51_ENST00000423169.2_Missense_Mutation_p.E169Q	NM_002875.4	NP_002866.2	Q06609	RAD51_HUMAN	RAD51 recombinase	169					DNA recombinase assembly|DNA unwinding involved in replication|mitotic recombination|positive regulation of DNA ligation|protein homooligomerization|reciprocal meiotic recombination	mitochondrial matrix|nucleus|perinuclear region of cytoplasm|PML body	ATP binding|damaged DNA binding|double-stranded DNA binding|identical protein binding|protein C-terminus binding|single-stranded DNA binding|single-stranded DNA-dependent ATPase activity			breast(2)|endometrium(1)|kidney(3)|large_intestine(1)|lung(1)|ovary(1)	9		all_cancers(109;1.19e-18)|all_epithelial(112;2.33e-15)|Lung NSC(122;5.34e-11)|all_lung(180;1.33e-09)|Melanoma(134;0.0574)|Ovarian(310;0.0822)|Colorectal(260;0.0946)		GBM - Glioblastoma multiforme(113;1.45e-05)|BRCA - Breast invasive adenocarcinoma(123;0.000421)|COAD - Colon adenocarcinoma(120;0.163)		CTTTAGGCCAGAACGGCTGCT	0.473000								Homologous recombination					7	43					0	0	0.001984	0	0
OR2W5	441932	broad.mit.edu	37	1	247655069	247655069	+	RNA	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:247655069C>T	ENST00000522351.1	+	0	700							A6NFC9	OR2W5_HUMAN							sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity	p.H214Y(1)		breast(1)|endometrium(5)|kidney(2)|large_intestine(2)|lung(24)|ovary(1)|skin(4)	39	all_cancers(71;4.51e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)	all_cancers(173;0.222)	OV - Ovarian serous cystadenocarcinoma(106;0.0188)			CGCTCTCCCTCATCCTCATCT	0.567000													9	103					0	0	0.004482	0	0
OR1S1	219959	broad.mit.edu	37	11	57983116	57983116	+	Silent	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:57983116C>G	ENST00000309433.6	+	1	900	c.900C>G	c.(898-900)ccC>ccG	p.P300P		NM_001004458.1	NP_001004458.1	Q8NH92	OR1S1_HUMAN	olfactory receptor, family 1, subfamily S, member 1	300					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|central_nervous_system(1)|endometrium(24)|kidney(1)|large_intestine(1)|liver(1)|lung(10)|prostate(1)|skin(2)|stomach(3)|urinary_tract(3)	48		Breast(21;0.0589)				TGATAAACCCCTTCATCTACA	0.453000													6	79					0	0	0.001168	0	0
MCTP2	55784	broad.mit.edu	37	15	94942203	94942203	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:94942203A>T	ENST00000357742.4	+	14	1802	c.1802A>T	c.(1801-1803)cAa>cTa	p.Q601L	MCTP2_ENST00000557742.1_Missense_Mutation_p.Q189L|MCTP2_ENST00000451018.3_Missense_Mutation_p.Q601L|MCTP2_ENST00000331706.4_Missense_Mutation_p.Q189L	NM_018349.3	NP_060819.3	Q6DN12	MCTP2_HUMAN	multiple C2 domains, transmembrane 2	601					calcium-mediated signaling	integral to membrane|membrane fraction	calcium ion binding			autonomic_ganglia(1)|breast(4)|cervix(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(12)|liver(1)|lung(12)|ovary(1)|pancreas(1)|skin(9)|stomach(2)	49	Lung NSC(78;0.0821)|all_lung(78;0.148)		BRCA - Breast invasive adenocarcinoma(143;0.0323)|OV - Ovarian serous cystadenocarcinoma(32;0.0593)			AGAGATGGACAACCGAATTGT	0.299000													13	82					0	0	0.013537	0	0
NDST1	3340	broad.mit.edu	37	5	149907815	149907815	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:149907815C>G	ENST00000261797.6	+	3	1465	c.963C>G	c.(961-963)atC>atG	p.I321M	NDST1_ENST00000523767.1_Missense_Mutation_p.I321M	NM_001543.4	NP_001534.1	P52848	NDST1_HUMAN	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	321	Heparan sulfate N-deacetylase 1.				heparan sulfate proteoglycan biosynthetic process|inflammatory response	Golgi membrane|integral to membrane	[heparan sulfate]-glucosamine N-sulfotransferase activity|hydrolase activity			breast(2)|central_nervous_system(3)|endometrium(5)|kidney(1)|large_intestine(6)|lung(10)|ovary(3)|skin(3)|upper_aerodigestive_tract(1)	34		all_hematologic(541;0.224)	KIRC - Kidney renal clear cell carcinoma(527;0.000785)|Kidney(363;0.00101)			TTGATGACATCTTCGTGGGCA	0.622000													3	43					0	0	0.009096	0	0
COL5A3	50509	broad.mit.edu	37	19	10079106	10079106	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:10079106C>T	ENST00000264828.3	-	59	4354	c.4269G>A	c.(4267-4269)caG>caA	p.Q1423Q		NM_015719.3	NP_056534.2	P25940	CO5A3_HUMAN	collagen, type V, alpha 3	1423	Triple-helical region.				collagen fibril organization|skin development	collagen type V	collagen binding|extracellular matrix structural constituent			NS(2)|breast(3)|central_nervous_system(2)|endometrium(11)|kidney(23)|large_intestine(12)|liver(2)|lung(35)|ovary(8)|prostate(5)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	116			Epithelial(33;7.11e-05)			CTGGCAACCCCTGATCTCCTT	0.602000													3	44					0	0	0.009096	0	0
SETBP1	26040	broad.mit.edu	37	18	42530630	42530630	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:42530630C>G	ENST00000282030.5	+	4	1621	c.1325C>G	c.(1324-1326)aCc>aGc	p.T442S		NM_015559.2	NP_056374.2	Q9Y6X0	SETBP_HUMAN	SET binding protein 1	442						nucleus	DNA binding			NS(1)|breast(2)|endometrium(9)|kidney(9)|large_intestine(20)|lung(47)|prostate(4)|skin(4)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(2)	104				Colorectal(1;0.0622)|COAD - Colon adenocarcinoma(74;0.201)		TCTGGAATCACCATGAGCAGT	0.448000									Schinzel-Giedion syndrome				9	118					0	0	0.006214	0	0
UQCC1	55245	broad.mit.edu	37	20	33969780	33969780	+	Missense_Mutation	SNP	C	C	T	rs143657027		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:33969780C>T	ENST00000397554.1	-	4	284	c.274G>A	c.(274-276)Gct>Act	p.A92T	UQCC_ENST00000491125.1_5'UTR|UQCC_ENST00000542501.1_Missense_Mutation_p.A92T|UQCC_ENST00000540457.1_Intron|UQCC_ENST00000407996.2_Intron|UQCC_ENST00000397556.3_5'UTR|UQCC_ENST00000374385.5_Missense_Mutation_p.A92T|UQCC_ENST00000374377.5_Intron|UQCC_ENST00000374380.2_Intron|UQCC_ENST00000374384.2_Missense_Mutation_p.A92T|UQCC_ENST00000359226.2_Missense_Mutation_p.A92T|UQCC_ENST00000349714.5_Missense_Mutation_p.A92T			Q9NVA1	UQCC_HUMAN		92						cytoplasmic membrane-bounded vesicle				breast(2)|endometrium(2)|large_intestine(4)|lung(7)|skin(1)|urinary_tract(1)	17			BRCA - Breast invasive adenocarcinoma(18;0.00252)			TTTGTGAAAGCACCAACCTTC	0.348000													15	163					0	0	0.003163	0	0
OBSCN	84033	broad.mit.edu	37	1	228487119	228487119	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:228487119G>T	ENST00000570156.2	+	50	13444	c.13370G>T	c.(13369-13371)gGg>gTg	p.G4457V	OBSCN_ENST00000366709.4_Intron|OBSCN_ENST00000284548.11_Intron|RP5-1139B12.4_ENST00000602778.1_RNA|OBSCN_ENST00000422127.1_Intron|OBSCN_ENST00000366707.4_Missense_Mutation_p.G1147V|OBSCN_ENST00000359599.6_3'UTR	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	3500	Ig-like 46.				apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				AGACAAGACGGGGCTGTGTGT	0.567000													19	127					5.45024e-15	7.69243e-15	0.018920	1	0
OTX1	5013	broad.mit.edu	37	2	63282636	63282636	+	Splice_Site	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:63282636G>T	ENST00000366671.3	+	5	526	c.249_splice	c.e5-1	p.V84_splice	OTX1_ENST00000282549.2_Splice_Site_p.V84_splice	NM_001199770.1	NP_001186699.1	P32242	OTX1_HUMAN	orthodenticle homeobox 1	84						nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			endometrium(1)|kidney(2)|large_intestine(6)|lung(6)|pancreas(2)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	20	Lung NSC(7;0.121)|all_lung(7;0.211)					CCCACTGCAGGTCTGGTTCAA	0.642000													3	24					2.0095e-06	2.63599e-06	0.001984	1	0
CEP290	80184	broad.mit.edu	37	12	88505592	88505592	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:88505592A>T	ENST00000552810.1	-	21	2439	c.2096T>A	c.(2095-2097)cTg>cAg	p.L699Q	CEP290_ENST00000397838.3_5'UTR|CEP290_ENST00000309041.7_Missense_Mutation_p.L701Q	NM_025114.3	NP_079390.3	O15078	CE290_HUMAN	centrosomal protein 290kDa	699					cilium assembly|eye photoreceptor cell development|G2/M transition of mitotic cell cycle|hindbrain development|otic vesicle formation|positive regulation of transcription, DNA-dependent|pronephros development|protein transport	cell surface|centrosome|cytosol|nucleus|photoreceptor connecting cilium	protein binding			breast(4)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(20)|liver(1)|lung(18)|ovary(5)|pancreas(1)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	73						TTTCAAATGCAGACTCGCATC	0.353000													4	33					0	0	0.009096	0	0
ZNF496	84838	broad.mit.edu	37	1	247464457	247464457	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:247464457C>T	ENST00000294753.4	-	9	1592	c.1128G>A	c.(1126-1128)ggG>ggA	p.G376G	ZNF496_ENST00000462139.1_5'UTR|ZNF496_ENST00000366498.2_Silent_p.G412G	NM_032752.1	NP_116141.1	Q96IT1	ZN496_HUMAN	zinc finger protein 496	376					positive regulation of transcription, DNA-dependent|viral reproduction		DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(2)|central_nervous_system(1)|cervix(1)|endometrium(6)|kidney(3)|large_intestine(5)|lung(13)|ovary(1)|prostate(1)|skin(2)|urinary_tract(1)	36	all_cancers(71;0.000136)|all_epithelial(71;2.62e-05)|Breast(184;0.0226)|Ovarian(71;0.0377)|all_lung(81;0.0607)|Lung NSC(105;0.0661)		OV - Ovarian serous cystadenocarcinoma(106;0.00703)			CTGTGGGGCTCCCCAGCTCTT	0.627000													4	4					0	0	0.014758	0	0
PABPC1	26986	broad.mit.edu	37	8	101719131	101719131	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:101719131C>G	ENST00000318607.5	-	10	2559	c.1431G>C	c.(1429-1431)atG>atC	p.M477I	PABPC1_ENST00000519004.1_Missense_Mutation_p.M432I|PABPC1_ENST00000519596.1_Intron|PABPC1_ENST00000522387.1_Missense_Mutation_p.M445I	NM_002568.3	NP_002559.2	P11940	PABP1_HUMAN	poly(A) binding protein, cytoplasmic 1	477					mRNA polyadenylation|mRNA stabilization|negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|nuclear-transcribed mRNA poly(A) tail shortening|translation	catalytic step 2 spliceosome|cytosol	nucleotide binding|poly(A) RNA binding|protein C-terminus binding|translation activator activity			breast(2)|endometrium(4)|kidney(15)|large_intestine(4)|lung(13)|prostate(1)|skin(1)	40	all_cancers(14;6.8e-05)|all_epithelial(15;3.16e-07)|Lung NSC(17;0.000453)|all_lung(17;0.00125)		Epithelial(11;6.37e-11)|all cancers(13;1.11e-08)|OV - Ovarian serous cystadenocarcinoma(57;3.91e-05)|STAD - Stomach adenocarcinoma(118;0.206)			GCTGTGTTGACATGACTCGTG	0.403000													20	82					0	0	0.014323	0	0
OPCML	4978	broad.mit.edu	37	11	132307151	132307151	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:132307151G>C	ENST00000331898.7	-	4	1207	c.629C>G	c.(628-630)gCg>gGg	p.A210G	OPCML_ENST00000541867.1_Missense_Mutation_p.A210G|OPCML_ENST00000524381.1_Missense_Mutation_p.A203G|OPCML_ENST00000374778.4_Missense_Mutation_p.A169G|OPCML_ENST00000529038.1_5'UTR	NM_002545.3	NP_002536.1	Q14982	OPCM_HUMAN	opioid binding protein/cell adhesion molecule-like	210	Ig-like C2-type 2.				cell adhesion|neuron recognition	anchored to membrane|integral to plasma membrane	opioid receptor activity			endometrium(5)|kidney(1)|large_intestine(12)|lung(17)|ovary(2)|skin(2)|urinary_tract(8)	47	all_hematologic(175;0.019)	all_cancers(12;5.86e-24)|all_epithelial(12;2.65e-17)|all_lung(97;2.89e-05)|Lung NSC(97;6.16e-05)|Breast(109;0.000126)|Medulloblastoma(222;0.0269)|all_neural(223;0.0326)|Esophageal squamous(93;0.129)		all cancers(11;4.61e-06)|OV - Ovarian serous cystadenocarcinoma(99;0.012)		CACATCGGGCGCAGCGACATC	0.552000													11	59					0	0	0.008291	0	0
TP53	7157	broad.mit.edu	37	17	7578212	7578212	+	Nonsense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:7578212G>A	ENST00000420246.2	-	6	769	c.637C>T	c.(637-639)Cga>Tga	p.R213*	TP53_ENST00000359597.4_Nonsense_Mutation_p.R213*|TP53_ENST00000445888.2_Nonsense_Mutation_p.R213*|TP53_ENST00000574684.1_Intron|TP53_ENST00000269305.4_Nonsense_Mutation_p.R213*|TP53_ENST00000455263.2_Nonsense_Mutation_p.R213*|TP53_ENST00000413465.2_Nonsense_Mutation_p.R213*	NM_001126114.2|NM_001276696.1	NP_001119586.1|NP_001263625.1	P04637	P53_HUMAN	tumor protein p53	213	Interaction with AXIN1 (By similarity).|Interaction with HIPK1 (By similarity).|Required for interaction with FBXO42.		R -> G (in sporadic cancers; somatic mutation).|R -> L (in sporadic cancers; somatic mutation).|R -> P (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> Q (in LFS; germline mutation and in sporadic cancers; somatic mutation).|R -> W (in sporadic cancers; somatic mutation).		activation of caspase activity by cytochrome c|base-excision repair|blood coagulation|cell cycle arrest|cell differentiation|cell proliferation|cellular protein localization|cellular response to drug|cellular response to glucose starvation|cellular response to hypoxia|cellular response to ionizing radiation|cellular response to UV|determination of adult lifespan|DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest|DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator|ER overload response|interspecies interaction between organisms|negative regulation of apoptosis|negative regulation of cell growth|negative regulation of cell proliferation|negative regulation of helicase activity|negative regulation of transcription from RNA polymerase II promoter|nucleotide-excision repair|oxidative stress-induced premature senescence|positive regulation of histone deacetylation|positive regulation of neuron apoptosis|positive regulation of peptidyl-tyrosine phosphorylation|positive regulation of reactive oxygen species metabolic process|positive regulation of thymocyte apoptosis|positive regulation of transcription from RNA polymerase II promoter|protein localization|protein tetramerization|Ras protein signal transduction|regulation of mitochondrial membrane permeability|replicative senescence|response to antibiotic|response to gamma radiation|response to X-ray	cytoplasm|cytosol|endoplasmic reticulum|insoluble fraction|mitochondrion|nuclear chromatin|nuclear matrix|nucleolus|nucleus|PML body|protein complex|replication fork	ATP binding|chaperone binding|chromatin binding|copper ion binding|damaged DNA binding|DNA strand annealing activity|histone acetyltransferase binding|p53 binding|protease binding|protein binding|protein heterodimerization activity|protein kinase binding|protein N-terminus binding|protein phosphatase 2A binding|RNA polymerase II transcription factor binding|sequence-specific DNA binding transcription factor activity|transcription regulatory region DNA binding|transcription repressor activity|ubiquitin protein ligase binding|zinc ion binding	p.R213*(250)|p.R81*(21)|p.R120*(21)|p.0?(8)|p.?(5)|p.R213G(5)|p.R213fs*35(3)|p.R213fs*34(3)|p.D208_V216delDRNTFRHSV(1)|p.R120G(1)|p.D207_R213delDDRNTFR(1)|p.T211_S215delTFRHS(1)|p.R81fs*>11(1)|p.D208fs*1(1)|p.R120fs*35(1)|p.R81G(1)|p.R209_R213delRNTFR(1)|p.R213fs*2(1)|p.T211fs*28(1)|p.R213_S215>X(1)|p.D207_V216del10(1)|p.R213R(1)|p.R213fs*32(1)|p.R209fs*6(1)|p.R213W(1)		NS(16)|adrenal_gland(37)|autonomic_ganglia(16)|biliary_tract(273)|bone(108)|breast(2530)|central_nervous_system(1264)|cervix(68)|endometrium(223)|eye(24)|fallopian_tube(1)|gastrointestinal_tract_(site_indeterminate)(1)|genital_tract(16)|haematopoietic_and_lymphoid_tissue(1301)|kidney(96)|large_intestine(5124)|liver(897)|lung(2388)|meninges(5)|oesophagus(1473)|ovary(1659)|pancreas(452)|penis(10)|peritoneum(33)|pituitary(4)|placenta(1)|pleura(3)|prostate(235)|salivary_gland(43)|skin(791)|small_intestine(14)|soft_tissue(220)|stomach(1158)|testis(11)|thymus(21)|thyroid(54)|upper_aerodigestive_tract(2271)|urinary_tract(1259)|vagina(6)|vulva(79)	24185		all_cancers(10;1.01e-06)|Myeloproliferative disorder(207;0.0122)|Prostate(122;0.081)		GBM - Glioblastoma multiforme(2;1.59e-06)|READ - Rectum adenocarcinoma(115;0.174)		ACACTATGTCGAAAAGTGTTT	0.532000		111	"""Mis, N, F"""		"""breast, colorectal, lung, sarcoma, adrenocortical, glioma, multiple other tumour types"""	"""breast, sarcoma, adrenocortical carcinoma, glioma, multiple other tumour types"""		Other conserved DNA damage response genes	Osteosarcoma, Familial Clustering of;Li-Fraumeni syndrome;Hereditary Breast-Ovarian Cancer, non-BRCA1/2;Hereditary Adrenocortical Cancer;Endometrial Cancer, Familial Clustering of	HNSCC(1;<9.43e-08)|TCGA GBM(1;<1E-08)|TSP Lung(2;<1E-08)|TCGA Ovarian(1;<1.89e-07)|Multiple Myeloma(5;0.019)			6	46					0	0	0.001168	0	0
WDFY3	23001	broad.mit.edu	37	4	85771114	85771114	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:85771114G>A	ENST00000322366.6	-	5	652	c.245C>T	c.(244-246)aCa>aTa	p.T82I	WDFY3_ENST00000295888.4_Missense_Mutation_p.T82I			Q8IZQ1	WDFY3_HUMAN	WD repeat and FYVE domain containing 3	82						cytoplasmic part|extrinsic to membrane|nuclear envelope	1-phosphatidylinositol binding|metal ion binding|protein binding			breast(5)|central_nervous_system(5)|endometrium(15)|haematopoietic_and_lymphoid_tissue(3)|kidney(8)|large_intestine(32)|lung(50)|ovary(3)|prostate(5)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(2)	134		Hepatocellular(203;0.114)		OV - Ovarian serous cystadenocarcinoma(123;0.000808)		TGAGACTTGTGTTGTGAACTG	0.373000													14	121					0	0	0.016723	0	0
EPRS	2058	broad.mit.edu	37	1	220154722	220154722	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:220154722C>A	ENST00000366923.3	-	24	3720	c.3451G>T	c.(3451-3453)Gtg>Ttg	p.V1151L		NM_004446.2	NP_004437.2	P07814	SYEP_HUMAN	glutamyl-prolyl-tRNA synthetase	1151	Prolyl-tRNA synthetase.				glutamyl-tRNA aminoacylation|prolyl-tRNA aminoacylation|protein complex assembly	cytosol|soluble fraction	ATP binding|glutamate-tRNA ligase activity|proline-tRNA ligase activity|protein binding|RNA binding			breast(2)|endometrium(11)|kidney(2)|large_intestine(13)|lung(24)|ovary(1)|prostate(3)|skin(2)|stomach(2)|urinary_tract(3)	63				GBM - Glioblastoma multiforme(131;0.0735)	L-Glutamic Acid(DB00142)|L-Proline(DB00172)	ATACCTACCACCACATTGCAC	0.363000													6	81					0.00307968	0.00339984	0.003080	1	0
ZNF599	148103	broad.mit.edu	37	19	35251308	35251308	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:35251308C>T	ENST00000329285.7	-	4	771	c.398G>A	c.(397-399)gGg>gAg	p.G133E		NM_001007248.2	NP_001007249.1	Q96NL3	ZN599_HUMAN	zinc finger protein 599	133					regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding			endometrium(3)|large_intestine(10)|lung(8)|ovary(1)|pancreas(1)|skin(1)	24	all_lung(56;1.13e-07)|Lung NSC(56;1.81e-07)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.138)			CCTCAAGTTCCCTTCCTGAAT	0.453000													6	68					0	0	0.001984	0	0
POP1	10940	broad.mit.edu	37	8	99169981	99169981	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:99169981C>T	ENST00000401707.2	+	16	2638	c.2557C>T	c.(2557-2559)Ccc>Tcc	p.P853S	POP1_ENST00000349693.3_Missense_Mutation_p.P853S	NM_001145860.1|NM_001145861.1	NP_001139332.1|NP_001139333.1	Q99575	POP1_HUMAN	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	853					tRNA 5'-leader removal|tRNA catabolic process	nucleolar ribonuclease P complex|ribonuclease MRP complex	identical protein binding|ribonuclease MRP activity|ribonuclease P activity			autonomic_ganglia(1)|breast(3)|endometrium(4)|large_intestine(9)|lung(15)|ovary(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	36	Breast(36;1.78e-06)		OV - Ovarian serous cystadenocarcinoma(57;0.145)			GGGCCACTTCCCCAGGGCCCT	0.642000													4	83					0	0	0.009096	0	0
FAM47A	158724	broad.mit.edu	37	X	34148898	34148898	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:34148898G>T	ENST00000346193.3	-	1	1549	c.1498C>A	c.(1498-1500)Cgg>Agg	p.R500R		NM_203408.3	NP_981953.2	Q5JRC9	FA47A_HUMAN	family with sequence similarity 47, member A	500			Missing.							NS(1)|biliary_tract(1)|breast(2)|central_nervous_system(1)|endometrium(9)|kidney(5)|large_intestine(17)|lung(44)|ovary(5)|prostate(2)|skin(4)|upper_aerodigestive_tract(4)|urinary_tract(2)	97						CTGGACGTCCGACGAGTCTTG	0.657000													5	31					1.12685e-05	1.40384e-05	0.004482	1	0
COL6A3	1293	broad.mit.edu	37	2	238277341	238277341	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:238277341C>G	ENST00000295550.4	-	10	5217	c.4765G>C	c.(4765-4767)Gac>Cac	p.D1589H	COL6A3_ENST00000346358.4_Missense_Mutation_p.D1389H|COL6A3_ENST00000353578.4_Missense_Mutation_p.D1383H|COL6A3_ENST00000347401.3_Missense_Mutation_p.D1388H|COL6A3_ENST00000409809.1_Missense_Mutation_p.D1383H|COL6A3_ENST00000472056.1_Missense_Mutation_p.D982H	NM_004369.3	NP_004360.2	P12111	CO6A3_HUMAN	collagen, type VI, alpha 3	1589	Nonhelical region.|VWFA 8.				axon guidance|cell adhesion|muscle organ development	collagen type VI|extracellular space	serine-type endopeptidase inhibitor activity			breast(6)|central_nervous_system(7)|cervix(3)|endometrium(7)|haematopoietic_and_lymphoid_tissue(2)|kidney(13)|large_intestine(64)|lung(62)|ovary(14)|pancreas(2)|prostate(11)|skin(14)|stomach(2)|upper_aerodigestive_tract(6)|urinary_tract(4)	217		Breast(86;0.000301)|Renal(207;0.000966)|all_hematologic(139;0.067)|Ovarian(221;0.0694)|all_lung(227;0.0943)|Melanoma(123;0.203)		Epithelial(121;1.23e-21)|OV - Ovarian serous cystadenocarcinoma(60;1.34e-10)|Kidney(56;5.71e-09)|KIRC - Kidney renal clear cell carcinoma(57;1.51e-07)|BRCA - Breast invasive adenocarcinoma(100;0.00025)|Lung(119;0.0142)|LUSC - Lung squamous cell carcinoma(224;0.034)		AGTCTGGGGTCATTGGTGATG	0.542000													15	197					0	0	0.004990	0	0
ROBO1	6091	broad.mit.edu	37	3	78763565	78763565	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:78763565C>T	ENST00000436010.2	-	6	1907	c.910G>A	c.(910-912)Gct>Act	p.A304T	ROBO1_ENST00000467549.1_Missense_Mutation_p.A304T|ROBO1_ENST00000495273.1_Missense_Mutation_p.A304T|ROBO1_ENST00000464233.1_Missense_Mutation_p.A343T			Q9Y6N7	ROBO1_HUMAN	roundabout, axon guidance receptor, homolog 1 (Drosophila)	343	Ig-like C2-type 3.				activation of caspase activity|axon midline choice point recognition|cell migration involved in sprouting angiogenesis|chemorepulsion involved in postnatal olfactory bulb interneuron migration|homophilic cell adhesion|negative regulation of chemokine-mediated signaling pathway|negative regulation of mammary gland epithelial cell proliferation|negative regulation of negative chemotaxis|positive regulation of axonogenesis|Roundabout signaling pathway	cell surface|cytoplasm|integral to plasma membrane	axon guidance receptor activity|identical protein binding|LRR domain binding			breast(1)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(2)|lung(25)|urinary_tract(1)	44		Lung SC(41;0.0257)|Lung NSC(201;0.0439)		LUSC - Lung squamous cell carcinoma(21;0.008)|Epithelial(33;0.00999)|Lung(72;0.0177)|BRCA - Breast invasive adenocarcinoma(55;0.0274)		GTCAGAGTAGCAGATGCTTCA	0.393000													8	71					0	0	0.004482	0	0
TRIM3	10612	broad.mit.edu	37	11	6472123	6472123	+	Splice_Site	SNP	T	T	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:6472123T>A	ENST00000525074.1	-	9	2263	c.1870_splice	c.e9+1	p.A623_splice	TRIM3_ENST00000345851.3_Splice_Site_p.A623_splice|TRIM3_ENST00000359518.3_Splice_Site_p.A623_splice|TRIM3_ENST00000537602.1_Splice_Site_p.A545_splice|TRIM3_ENST00000536344.1_Splice_Site_p.A504_splice	NM_001248006.1	NP_001234935.1	O75382	TRIM3_HUMAN	tripartite motif containing 3	623					nervous system development|protein transport	early endosome	protein C-terminus binding|zinc ion binding			breast(1)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(8)|ovary(1)|prostate(2)|skin(3)	27		all_lung(207;9.97e-06)|Lung NSC(207;1.74e-05)|Medulloblastoma(188;0.00225)|Breast(177;0.0204)|all_neural(188;0.0212)		Epithelial(150;9.34e-10)|Lung(200;0.0234)|LUSC - Lung squamous cell carcinoma(625;0.133)|BRCA - Breast invasive adenocarcinoma(625;0.135)		CCCCTATACCTGCAAAGTGGC	0.552000													4	28					0	0	0.001168	0	0
MUC16	94025	broad.mit.edu	37	19	9074052	9074052	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:9074052G>T	ENST00000397910.4	-	3	13597	c.13394C>A	c.(13393-13395)cCt>cAt	p.P4465H		NM_024690.2	NP_078966.2	Q8WXI7	MUC16_HUMAN	mucin 16, cell surface associated	4467	Thr-rich.				cell adhesion	extracellular space|extrinsic to membrane|integral to membrane|plasma membrane	protein binding			NS(9)|autonomic_ganglia(1)|breast(26)|central_nervous_system(11)|cervix(1)|endometrium(46)|haematopoietic_and_lymphoid_tissue(5)|kidney(35)|large_intestine(91)|liver(1)|lung(278)|ovary(17)|pancreas(2)|prostate(17)|skin(18)|soft_tissue(1)|stomach(8)|upper_aerodigestive_tract(16)|urinary_tract(7)	590						AGTGGCAGGAGGTATGGTTGT	0.502000													11	129					6.40141e-05	7.7163e-05	0.010729	1	0
CHD7	55636	broad.mit.edu	37	8	61757453	61757453	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:61757453C>G	ENST00000423902.2	+	22	5360	c.4881C>G	c.(4879-4881)caC>caG	p.H1627Q	CHD7_ENST00000524602.1_Intron	NM_017780.3	NP_060250.2	Q9P2D1	CHD7_HUMAN	chromodomain helicase DNA binding protein 7	1627					central nervous system development|chromatin modification|cognition|cranial nerve development|face development|heart morphogenesis|in utero embryonic development|inner ear morphogenesis|nose development|palate development|regulation of growth hormone secretion|regulation of transcription, DNA-dependent|retina development in camera-type eye|skeletal system development|T cell differentiation|transcription, DNA-dependent	nucleus	ATP binding|chromatin binding|DNA binding|helicase activity			NS(1)|breast(6)|central_nervous_system(8)|cervix(2)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(16)|lung(49)|ovary(4)|pancreas(2)|prostate(4)|skin(2)|urinary_tract(3)	123		all_cancers(86;0.2)|all_lung(136;0.0402)|Lung NSC(129;0.0459)|all_epithelial(80;0.0477)	BRCA - Breast invasive adenocarcinoma(89;0.143)			TTCTTTCCCACGGACGCTATA	0.443000													3	67					0	0	0.014758	0	0
ZNF99	7652	broad.mit.edu	37	19	22940373	22940373	+	Missense_Mutation	SNP	T	T	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:22940373T>C	ENST00000397104.3	-	5	2064	c.2065A>G	c.(2065-2067)Aag>Gag	p.K689E	ZNF99_ENST00000596209.1_Missense_Mutation_p.K780E					zinc finger protein 99									p.K689E(3)		NS(1)|breast(1)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(20)|lung(55)|ovary(2)|prostate(10)|skin(5)|stomach(9)|upper_aerodigestive_tract(2)|urinary_tract(3)	124		Lung NSC(12;0.0207)|all_lung(12;0.0214)|all_epithelial(12;0.102)				TGAATTATCTTATGTTTTCTA	0.343000													3	58					0	0	0.009096	0	0
FAM160B1	57700	broad.mit.edu	37	10	116621056	116621056	+	Nonsense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:116621056A>T	ENST00000369248.4	+	16	2490	c.2155A>T	c.(2155-2157)Aga>Tga	p.R719*	FAM160B1_ENST00000369250.3_Nonsense_Mutation_p.R719*	NM_020940.3	NP_065991.3	Q5W0V3	F16B1_HUMAN	family with sequence similarity 160, member B1	719										NS(1)|central_nervous_system(3)|endometrium(2)|kidney(1)|large_intestine(5)|lung(13)	25						TCTGTTAGTCAGAAAGCGGTT	0.413000													11	73					0	0	0.013537	0	0
SELPLG	6404	broad.mit.edu	37	12	109017870	109017870	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:109017870G>A	ENST00000388962.3	-	2	373	c.214C>T	c.(214-216)Ctg>Ttg	p.L72L	SELPLG_ENST00000550948.1_Silent_p.L72L|SELPLG_ENST00000228463.6_Silent_p.L88L	NM_003006.4	NP_002997.2	Q14242	SELPL_HUMAN	selectin P ligand	72					blood coagulation|cellular response to interleukin-6	integral to plasma membrane|membrane fraction	bacterial cell surface binding|receptor binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(3)|lung(3)|prostate(3)|skin(1)	12						GGCCCAGTCAGAGGAGTGGTG	0.572000													10	52					0	0	0.008291	0	0
NUP188	23511	broad.mit.edu	37	9	131730947	131730947	+	Missense_Mutation	SNP	A	A	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:131730947A>C	ENST00000372577.2	+	9	769	c.748A>C	c.(748-750)Aat>Cat	p.N250H		NM_015354.1	NP_056169.1	Q5SRE5	NU188_HUMAN	nucleoporin 188kDa	250					carbohydrate metabolic process|glucose transport|mRNA transport|protein transport|regulation of glucose transport|transmembrane transport|viral reproduction	nuclear pore	protein binding			breast(2)|central_nervous_system(3)|endometrium(6)|kidney(4)|large_intestine(9)|lung(20)|ovary(6)|prostate(4)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	60						TAGGCAGACCAATAGGCACCT	0.388000													9	110					0	0	0.008291	0	0
FOCAD	54914	broad.mit.edu	37	9	20981490	20981490	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:20981490G>T	ENST00000380249.1	+	40	4807	c.4443G>T	c.(4441-4443)caG>caT	p.Q1481H	FOCAD_ENST00000605086.1_Missense_Mutation_p.Q917H|FOCAD_ENST00000338382.6_Missense_Mutation_p.Q1481H	NM_017794.3	NP_060264.3	Q5VW36	K1797_HUMAN	focadhesin	1481						integral to membrane	binding										CTGATGAACAGATCCTGGGTT	0.428000													8	77					1.12685e-05	1.40384e-05	0.004482	1	0
ADPRH	141	broad.mit.edu	37	3	119305362	119305362	+	Missense_Mutation	SNP	C	C	A	rs143222300		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:119305362C>A	ENST00000478399.1	+	3	1934	c.529C>A	c.(529-531)Ctt>Att	p.L177I	ADPRH_ENST00000465513.1_Missense_Mutation_p.L177I|ADPRH_ENST00000357003.3_Missense_Mutation_p.L177I|ADPRH_ENST00000478927.1_Missense_Mutation_p.L177I|ADPRH_ENST00000471850.1_3'UTR			P54922	ADPRH_HUMAN	ADP-ribosylarginine hydrolase	177					protein de-ADP-ribosylation		ADP-ribosylarginine hydrolase activity|magnesium ion binding			breast(1)|kidney(1)|lung(10)|ovary(1)	13		Lung NSC(201;0.0977)		GBM - Glioblastoma multiforme(114;0.23)		TGCGTCTGCTCTTTTTACAGC	0.527000													10	88					7.48243e-07	9.87326e-07	0.006214	1	0
MGAT5	4249	broad.mit.edu	37	2	135107435	135107435	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:135107435A>G	ENST00000409645.1	+	10	1424	c.1172A>G	c.(1171-1173)tAt>tGt	p.Y391C	MGAT5_ENST00000281923.2_Missense_Mutation_p.Y391C			Q09328	MGT5A_HUMAN	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase	391					post-translational protein modification|protein N-linked glycosylation via asparagine	Golgi membrane|integral to membrane	alpha-1,6-mannosyl-glycoprotein 6-beta-N-acetylglucosaminyltransferase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(3)|liver(1)|lung(18)|ovary(3)|pancreas(1)|skin(3)	36				BRCA - Breast invasive adenocarcinoma(221;0.0964)		CATGCAAATTATGCCCAATCG	0.423000													11	161					0	0	0.010729	0	0
GATA5	140628	broad.mit.edu	37	20	61039976	61039976	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:61039976G>T	ENST00000252997.2	-	7	1171	c.1110C>A	c.(1108-1110)gcC>gcA	p.A370A		NM_080473.4	NP_536721.1	Q9BWX5	GATA5_HUMAN	GATA binding protein 5	370					blood coagulation|intestinal epithelial cell differentiation|positive regulation of transcription from RNA polymerase II promoter	nucleoplasm	sequence-specific DNA binding|transcription regulatory region DNA binding|zinc ion binding			kidney(1)|lung(3)|ovary(1)|stomach(1)	6	Breast(26;2.05e-08)		BRCA - Breast invasive adenocarcinoma(19;3.08e-06)			TGGAGGGGAAGGCAAAGTCCT	0.672000													4	9					0.00909568	0.00979873	0.009096	1	0
MYH4	4622	broad.mit.edu	37	17	10356999	10356999	+	Silent	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:10356999C>A	ENST00000255381.2	-	23	3005	c.2895G>T	c.(2893-2895)ctG>ctT	p.L965L	CTC-297N7.7_ENST00000399342.2_RNA|CTC-297N7.7_ENST00000581304.1_RNA|CTC-297N7.7_ENST00000587182.1_RNA	NM_017533.2	NP_060003.2	Q9Y623	MYH4_HUMAN	myosin, heavy chain 4, skeletal muscle	965					muscle filament sliding	muscle myosin complex|myosin filament|sarcomere	actin binding|ATP binding|calmodulin binding|microfilament motor activity|structural constituent of muscle			NS(4)|breast(8)|central_nervous_system(2)|cervix(1)|endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(13)|lung(72)|ovary(10)|prostate(7)|skin(9)|stomach(1)|upper_aerodigestive_tract(2)|urinary_tract(3)	149						CAACCTTGGCCAGTGTCAGCT	0.398000													12	149					4.93089e-13	6.87243e-13	0.020292	1	0
DAPK2	23604	broad.mit.edu	37	15	64332369	64332369	+	Splice_Site	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:64332369C>A	ENST00000261891.3	-	1	97	c.92_splice	c.e1+1	p.S31_splice	DAPK2_ENST00000558069.1_Splice_Site_p.S31_splice|DAPK2_ENST00000457488.1_Splice_Site_p.S31_splice|DAPK2_ENST00000558482.1_5'UTR			Q9UIK4	DAPK2_HUMAN	death-associated protein kinase 2	31	Protein kinase.				apoptosis|induction of apoptosis|intracellular protein kinase cascade	cytoplasm	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity|identical protein binding			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(2)|lung(2)|skin(1)|stomach(1)	11				LUAD - Lung adenocarcinoma(2;0.215)		AGTCTCCTACCTCCCCAGCTC	0.547000													10	67					0.00621372	0.00679244	0.006214	1	0
ROCK1	6093	broad.mit.edu	37	18	18690844	18690844	+	Nonsense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:18690844G>A	ENST00000399799.1	-	1	968	c.28C>T	c.(28-30)Cga>Tga	p.R10*		NM_005406.2	NP_005397.1	Q13464	ROCK1_HUMAN	Rho-associated, coiled-coil containing protein kinase 1	10					actin cytoskeleton organization|axon guidance|cellular component disassembly involved in apoptosis|cytokinesis|leukocyte tethering or rolling|membrane to membrane docking|Rho protein signal transduction	centriole|cytosol|Golgi membrane	ATP binding|identical protein binding|metal ion binding|protein serine/threonine kinase activity			NS(1)|breast(4)|central_nervous_system(1)|large_intestine(8)|lung(2)	16	Melanoma(1;0.165)					TTTTCAAATCGAGTCTCAAAA	0.502000													9	66					0	0	0.006214	0	0
LRRC55	219527	broad.mit.edu	37	11	56949738	56949738	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:56949738C>T	ENST00000497933.1	+	1	518	c.371C>T	c.(370-372)cCg>cTg	p.P124L		NM_001005210.2	NP_001005210.1	Q6ZSA7	LRC55_HUMAN	leucine rich repeat containing 55	94						integral to membrane				endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(1)|large_intestine(2)|lung(13)|ovary(2)|skin(2)	25						ACAGCAGTGCCGCCTGGCTAC	0.607000													4	34					0	0	0.014758	0	0
ATG3	64422	broad.mit.edu	37	3	112255402	112255402	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:112255402C>A	ENST00000402314.2	-	10	1101	c.714G>T	c.(712-714)caG>caT	p.Q238H	ATG3_ENST00000283290.5_Missense_Mutation_p.Q238H|ATG3_ENST00000495756.1_5'UTR			Q9NT62	ATG3_HUMAN	autophagy related 3	238					autophagic vacuole assembly|mitochondrial fragmentation involved in apoptosis|protein targeting to membrane|protein ubiquitination	cytoplasmic ubiquitin ligase complex|cytosol	Atg12 ligase activity|Atg8 ligase activity|enzyme binding			breast(1)|kidney(1)|large_intestine(1)|lung(3)|ovary(3)	9						TCACATGATCCTGACTGATGT	0.433000													9	56					7.48243e-07	9.87326e-07	0.006214	1	0
KMT2D	8085	broad.mit.edu	37	12	49437156	49437156	+	Silent	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:49437156G>C	ENST00000301067.7	-	24	5522	c.5523C>G	c.(5521-5523)gcC>gcG	p.A1841A		NM_003482.3	NP_003473.3			lysine (K)-specific methyltransferase 2D																		CTGGTGTATCGGCTTTGCCCT	0.562000											OREG0021780	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	32	175					0	0	0.021022	0	0
SGOL2	151246	broad.mit.edu	37	2	201435837	201435837	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:201435837G>C	ENST00000357799.4	+	7	866	c.768G>C	c.(766-768)caG>caC	p.Q256H		NM_001160033.1|NM_001160046.1|NM_152524.5	NP_001153505.1|NP_001153518.1|NP_689737.4	Q562F6	SGOL2_HUMAN	shugoshin-like 2 (S. pombe)	256					cell division|mitotic prometaphase	condensed chromosome kinetochore|cytosol|mitotic cohesin complex	protein binding			NS(2)|breast(2)|cervix(3)|endometrium(1)|kidney(2)|large_intestine(7)|lung(20)|ovary(2)|prostate(2)|skin(2)|stomach(1)|urinary_tract(2)	46						GAAACGCCCAGTCTATTGGCC	0.418000													4	59					0	0	0.009096	0	0
CES1	1066	broad.mit.edu	37	16	55846924	55846924	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:55846924C>G	ENST00000422046.2	-	9	1255	c.974G>C	c.(973-975)gGg>gCg	p.G325A	CES1_ENST00000360526.3_Missense_Mutation_p.G326A|CES1_ENST00000361503.4_Missense_Mutation_p.G325A			P23141	EST1_HUMAN	carboxylesterase 1	325					response to toxin	endoplasmic reticulum lumen	carboxylesterase activity|methyl indole-3-acetate esterase activity|methyl jasmonate esterase activity|methyl salicylate esterase activity								all cancers(182;0.13)|Epithelial(162;0.137)	Aminoglutethimide(DB00357)|Bezafibrate(DB01393)|Cholestyramine(DB01432)|Moexipril(DB00691)	CAGCAGCATCCCATCAATCAC	0.527000													3	43					0	0	0.014758	0	0
BTBD3	22903	broad.mit.edu	37	20	11900471	11900471	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:11900471C>T	ENST00000405977.1	+	4	1148	c.523C>T	c.(523-525)Ctc>Ttc	p.L175F	BTBD3_ENST00000254977.3_Missense_Mutation_p.L114F|BTBD3_ENST00000399006.2_Missense_Mutation_p.L114F|BTBD3_ENST00000488503.1_3'UTR|BTBD3_ENST00000378226.2_Missense_Mutation_p.L175F			Q9Y2F9	BTBD3_HUMAN	BTB (POZ) domain containing 3	175	BTB.									breast(2)|central_nervous_system(1)|endometrium(5)|kidney(1)|large_intestine(2)|lung(18)|ovary(3)|skin(2)	34						TGCTGCTTTTCTCGCTATGCT	0.413000													10	54					0	0	0.020292	0	0
DACT1	51339	broad.mit.edu	37	14	59107505	59107505	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:59107505G>T	ENST00000395153.3	+	2	544	c.397G>T	c.(397-399)Gac>Tac	p.D133Y	DACT1_ENST00000541264.2_5'UTR|DACT1_ENST00000335867.4_Missense_Mutation_p.D133Y|DACT1_ENST00000555845.1_3'UTR|DACT1_ENST00000556859.1_5'UTR|DACT1_ENST00000395151.3_5'UTR	NM_001079520.1|NM_016651.5	NP_001072988.1|NP_057735.2	Q9NYF0	DACT1_HUMAN	dishevelled-binding antagonist of beta-catenin 1	133					multicellular organismal development|Wnt receptor signaling pathway	cytoplasm|nucleus				endometrium(7)|kidney(3)|large_intestine(11)|lung(27)|ovary(1)|prostate(3)|upper_aerodigestive_tract(1)	53						GCAAGAGCTTGACAAGCAGAT	0.453000													5	100					0.000157383	0.000184718	0.003080	1	0
CFHR1	3078	broad.mit.edu	37	1	196796071	196796071	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:196796071C>T	ENST00000320493.5	+	3	454	c.366C>T	c.(364-366)aaC>aaT	p.N122N	CFHR1_ENST00000498248.1_3'UTR|CFHR2_ENST00000367421.3_Intron|CFHR1_ENST00000367424.3_Silent_p.N122N	NM_002113.2	NP_002104.2	Q03591	FHR1_HUMAN	complement factor H-related 1	122	Sushi 2.				complement activation	extracellular space				NS(1)|kidney(1)|large_intestine(2)|lung(7)	11						GACTTCAAAACAATGAGAACA	0.418000													11	101					0	0	0.008291	0	0
TTC38	55020	broad.mit.edu	37	22	46685772	46685772	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:46685772C>T	ENST00000381031.3	+	13	1368	c.1292C>T	c.(1291-1293)tCc>tTc	p.S431F	TTC38_ENST00000445282.2_Missense_Mutation_p.S373F	NM_017931.2	NP_060401.2	Q5R3I4	TTC38_HUMAN	tetratricopeptide repeat domain 38	431							binding			endometrium(4)|large_intestine(3)|lung(4)|ovary(1)	12						AACTGCACCTCCAGCGTCCAT	0.597000													5	30					0	0	0.014758	0	0
PFKFB2	5208	broad.mit.edu	37	1	207235398	207235398	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:207235398C>T	ENST00000367080.3	+	3	310	c.186C>T	c.(184-186)ctC>ctT	p.L62L	PFKFB2_ENST00000545806.1_Silent_p.L29L|PFKFB2_ENST00000411990.2_5'UTR|PFKFB2_ENST00000367079.2_Silent_p.L62L	NM_006212.2	NP_006203.2	O60825	F262_HUMAN	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	62	6-phosphofructo-2-kinase.				fructose 2,6-bisphosphate metabolic process|glycolysis	cytosol	6-phosphofructo-2-kinase activity|ATP binding|fructose-2,6-bisphosphate 2-phosphatase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(2)|kidney(2)|large_intestine(3)|liver(1)|lung(7)|ovary(1)|skin(1)|urinary_tract(1)	20	Prostate(682;0.19)					CACGCTACCTCAACTGGATTG	0.498000													4	45					0	0	0.014758	0	0
HADHB	3032	broad.mit.edu	37	2	26486289	26486289	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:26486289A>T	ENST00000317799.5	+	4	255	c.151A>T	c.(151-153)Ata>Tta	p.I51L	HADHB_ENST00000545822.1_Missense_Mutation_p.I29L|HADHB_ENST00000537713.1_Missense_Mutation_p.I51L|HADHB_ENST00000405867.3_Missense_Mutation_p.I51L|HADHB_ENST00000494615.1_3'UTR	NM_000183.2	NP_000174.1	P55084	ECHB_HUMAN	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	51					fatty acid beta-oxidation	mitochondrial nucleoid	3-hydroxyacyl-CoA dehydrogenase activity|acetyl-CoA C-acyltransferase activity|enoyl-CoA hydratase activity|protein binding			breast(1)|endometrium(2)|kidney(1)|large_intestine(5)|lung(7)|ovary(1)|prostate(1)|skin(1)	19	Acute lymphoblastic leukemia(172;0.155)|all_hematologic(175;0.215)					CAAACCCAATATAAGGAATGT	0.338000													12	61					0	0	0.006122	0	0
KMT2E	55904	broad.mit.edu	37	7	104742407	104742407	+	Silent	SNP	T	T	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:104742407T>C	ENST00000334877.4	+	17	2496	c.1962T>C	c.(1960-1962)ttT>ttC	p.F654F	KMT2E_ENST00000311117.3_Silent_p.F654F|KMT2E_ENST00000257745.4_Silent_p.F654F|KMT2E_ENST00000334914.7_5'UTR					lysine (K)-specific methyltransferase 2E																		GAAAAAGTTTTTCTCGGAGTA	0.408000													19	103					0	0	0.016522	0	0
PCLO	27445	broad.mit.edu	37	7	82583174	82583174	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:82583174C>T	ENST00000423517.2	-	5	7432	c.7095G>A	c.(7093-7095)gaG>gaA	p.E2365E	PCLO_ENST00000333891.8_Silent_p.E2365E	NM_014510.2	NP_055325.2	Q9Y6V0	PCLO_HUMAN	piccolo presynaptic cytomatrix protein	2296	Pro-rich.				cytoskeleton organization|synaptic vesicle exocytosis	cell junction|cytoskeleton|synaptic vesicle	calcium ion binding|calcium-dependent phospholipid binding|profilin binding|transporter activity			breast(3)|central_nervous_system(3)|cervix(5)|endometrium(19)|haematopoietic_and_lymphoid_tissue(3)|kidney(19)|large_intestine(35)|lung(145)|ovary(7)|prostate(4)|upper_aerodigestive_tract(14)|urinary_tract(2)	259						GACCAAAGGTCTCTCCAGATG	0.433000													4	79					0	0	0.009096	0	0
LEPRE1	64175	broad.mit.edu	37	1	43221286	43221286	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:43221286C>T	ENST00000236040.4	-	6	1143	c.1103G>A	c.(1102-1104)cGa>cAa	p.R368Q	LEPRE1_ENST00000296388.5_Missense_Mutation_p.R368Q|LEPRE1_ENST00000397054.3_Missense_Mutation_p.R368Q	NM_001243246.1	NP_001230175.1	Q32P28	P3H1_HUMAN	leucine proline-enriched proteoglycan (leprecan) 1	368					negative regulation of cell proliferation	endoplasmic reticulum|proteinaceous extracellular matrix	iron ion binding|L-ascorbic acid binding|oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen|procollagen-proline 3-dioxygenase activity			large_intestine(2)|lung(15)|ovary(5)|prostate(1)|urinary_tract(3)	26	Ovarian(52;0.00744)|all_hematologic(146;0.0977)|Acute lymphoblastic leukemia(166;0.155)	Myeloproliferative disorder(586;0.0505)			L-Proline(DB00172)|Succinic acid(DB00139)|Vitamin C(DB00126)	CAGTAGGCTTCGCTGTCGGTA	0.517000													8	89					0	0	0.004482	0	0
RYR2	6262	broad.mit.edu	37	1	237608811	237608811	+	Silent	SNP	T	T	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:237608811T>C	ENST00000366574.2	+	14	1598	c.1281T>C	c.(1279-1281)aaT>aaC	p.N427N	RYR2_ENST00000542537.1_Silent_p.N411N|RYR2_ENST00000360064.6_Silent_p.N425N	NM_001035.2	NP_001026.2	Q92736	RYR2_HUMAN	ryanodine receptor 2 (cardiac)	427					cardiac muscle contraction|detection of calcium ion|induction of apoptosis by ionic changes|regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion|release of sequestered calcium ion into cytosol by sarcoplasmic reticulum|response to caffeine|response to hypoxia|response to redox state	calcium channel complex|cytosol|plasma membrane|plasma membrane enriched fraction|sarcoplasmic reticulum membrane	calcium ion binding|calmodulin binding|identical protein binding|protein kinase A catalytic subunit binding|protein kinase A regulatory subunit binding|receptor activity|ryanodine-sensitive calcium-release channel activity|suramin binding			NS(4)|breast(8)|central_nervous_system(11)|cervix(2)|endometrium(39)|haematopoietic_and_lymphoid_tissue(5)|kidney(17)|large_intestine(83)|liver(4)|lung(353)|ovary(18)|pancreas(5)|prostate(12)|skin(8)|stomach(1)|upper_aerodigestive_tract(12)|urinary_tract(4)	586	Ovarian(103;0.103)	all_cancers(173;0.000368)|Melanoma(53;0.0179)|all_epithelial(177;0.0225)	OV - Ovarian serous cystadenocarcinoma(106;0.00606)			TCCTTTTCAATAGATTTATAA	0.368000													20	101					0	0	0.010504	0	0
SLC37A3	84255	broad.mit.edu	37	7	140051137	140051137	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:140051137C>A	ENST00000326232.9	-	9	1021	c.818G>T	c.(817-819)aGt>aTt	p.S273I	SLC37A3_ENST00000340308.3_Missense_Mutation_p.S273I|SLC37A3_ENST00000447932.2_Missense_Mutation_p.S273I|SLC37A3_ENST00000429996.2_3'UTR	NM_207113.1	NP_996996.1	Q8NCC5	SPX3_HUMAN	solute carrier family 37, member 3	273					carbohydrate transport|transmembrane transport	integral to membrane				endometrium(4)|kidney(1)|large_intestine(5)|lung(7)|ovary(3)|prostate(1)|stomach(3)	24	Melanoma(164;0.0142)					GGCAACAGAACTATCATCTTG	0.453000													7	63					5.18039e-06	6.6013e-06	0.003080	1	0
WDR17	116966	broad.mit.edu	37	4	177017722	177017722	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:177017722G>C	ENST00000280190.4	+	2	208	c.52G>C	c.(52-54)Gaa>Caa	p.E18Q	WDR17_ENST00000508596.1_Intron|WDR17_ENST00000393643.2_Intron|WDR17_ENST00000509792.1_Intron|WDR17_ENST00000507824.2_Missense_Mutation_p.E18Q			Q8IZU2	WDR17_HUMAN	WD repeat domain 17	18										breast(2)|central_nervous_system(1)|cervix(1)|endometrium(3)|kidney(2)|large_intestine(18)|lung(46)|ovary(2)|pancreas(1)|prostate(3)|skin(5)|stomach(1)|upper_aerodigestive_tract(6)|urinary_tract(1)	92		Breast(14;0.00015)|Melanoma(52;0.00886)|Prostate(90;0.00996)|Renal(120;0.0183)|all_hematologic(60;0.107)|all_neural(102;0.164)		all cancers(43;2.21e-20)|Epithelial(43;9.71e-18)|OV - Ovarian serous cystadenocarcinoma(60;2.38e-09)|GBM - Glioblastoma multiforme(59;0.000295)|STAD - Stomach adenocarcinoma(60;0.000703)|LUSC - Lung squamous cell carcinoma(193;0.0232)		TGATTGGTATGAAGGACTACA	0.323000													10	96					0	0	0.008291	0	0
LYST	1130	broad.mit.edu	37	1	235970013	235970013	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:235970013C>T	ENST00000389794.3	-	6	2597	c.2423G>A	c.(2422-2424)tGc>tAc	p.C808Y	LYST_ENST00000536965.1_Missense_Mutation_p.C808Y|LYST_ENST00000389793.2_Missense_Mutation_p.C808Y			Q99698	LYST_HUMAN	lysosomal trafficking regulator	808					defense response to bacterium|defense response to protozoan|defense response to virus|endosome to lysosome transport via multivesicular body sorting pathway|leukocyte chemotaxis|mast cell secretory granule organization|melanosome organization|natural killer cell mediated cytotoxicity|protein transport	cytoplasm|microtubule cytoskeleton	protein binding			NS(1)|breast(13)|central_nervous_system(3)|cervix(3)|endometrium(17)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(27)|lung(66)|ovary(7)|pancreas(1)|prostate(4)|skin(4)|stomach(1)|upper_aerodigestive_tract(5)|urinary_tract(1)	162	Ovarian(103;0.0634)|Breast(184;0.23)	all_cancers(173;0.00246)|Prostate(94;0.0771)|Acute lymphoblastic leukemia(190;0.228)	OV - Ovarian serous cystadenocarcinoma(106;0.000674)			ACCATTTAAGCAATTTAATTC	0.328000													5	62					0	0	0.014758	0	0
SFTPB	6439	broad.mit.edu	37	2	85893804	85893804	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:85893804G>A	ENST00000342375.3	-	5	464	c.329C>T	c.(328-330)cCc>cTc	p.P110L	SFTPB_ENST00000409383.1_Missense_Mutation_p.P122L|SFTPB_ENST00000393822.3_Missense_Mutation_p.P122L|SFTPB_ENST00000519937.2_Missense_Mutation_p.P110L	NM_000542.3|NM_198843.2	NP_000533.3|NP_942140.2	P07988	PSPB_HUMAN	surfactant protein B	110	Saposin B-type 1.				organ morphogenesis|respiratory gaseous exchange|sphingolipid metabolic process	extracellular space|lysosome				central_nervous_system(1)|endometrium(1)|large_intestine(6)|lung(3)|ovary(1)|prostate(1)|skin(3)	16						GTTGCACTGGGGCATGAGCAG	0.612000													11	163					0	0	0.020292	0	0
NDN	4692	broad.mit.edu	37	15	23931409	23931409	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:23931409G>A	ENST00000331837.4	-	1	1041	c.956C>T	c.(955-957)tCt>tTt	p.S319F		NM_002487.2	NP_002478.1	Q99608	NECD_HUMAN	necdin, melanoma antigen (MAGE) family member	319					negative regulation of cell proliferation|regulation of growth|regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus|perikaryon	DNA binding			breast(2)|endometrium(3)|kidney(2)|large_intestine(5)|lung(23)|ovary(1)|prostate(2)|skin(1)	39		all_cancers(20;1.78e-24)|all_epithelial(15;7.75e-22)|Lung NSC(15;2.96e-18)|all_lung(15;2.8e-17)|Breast(32;0.000625)|Colorectal(260;0.14)		all cancers(64;8.37e-11)|Epithelial(43;9.29e-10)|BRCA - Breast invasive adenocarcinoma(123;0.00179)|GBM - Glioblastoma multiforme(186;0.018)|Lung(196;0.153)		CTAGTCCTCAGAGACACTGCT	0.577000									Prader-Willi syndrome				4	62					0	0	0.001168	0	0
KIF21B	23046	broad.mit.edu	37	1	200971448	200971448	+	Nonsense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:200971448C>A	ENST00000332129.2	-	9	1559	c.1243G>T	c.(1243-1245)Gag>Tag	p.E415*	KIF21B_ENST00000461742.2_Nonsense_Mutation_p.E415*|KIF21B_ENST00000422435.2_Nonsense_Mutation_p.E415*|KIF21B_ENST00000360529.5_Nonsense_Mutation_p.E415*	NM_001252102.1|NM_001252103.1|NM_017596.3	NP_001239031.1|NP_001239032.1|NP_060066.2	O75037	KI21B_HUMAN	kinesin family member 21B	415					microtubule-based movement	cytoplasm|microtubule	ATP binding|microtubule motor activity			autonomic_ganglia(1)|breast(4)|central_nervous_system(1)|cervix(1)|endometrium(15)|kidney(4)|large_intestine(8)|liver(1)|lung(27)|ovary(3)|pancreas(1)|prostate(5)|skin(8)|stomach(2)|urinary_tract(2)	83						CTATAGCCCTCAGCGCCATCC	0.607000													11	62					1.08611e-07	1.47684e-07	0.010729	1	0
ZHX1	11244	broad.mit.edu	37	8	124267459	124267459	+	Missense_Mutation	SNP	T	T	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:124267459T>A	ENST00000395571.3	-	3	1345	c.728A>T	c.(727-729)cAt>cTt	p.H243L	ZHX1_ENST00000297857.2_Missense_Mutation_p.H243L|ZHX1-C8ORF76_ENST00000357082.4_Intron|ZHX1_ENST00000522655.1_Missense_Mutation_p.H243L	NM_001017926.2|NM_007222.4	NP_001017926.1|NP_009153.3	Q9UKY1	ZHX1_HUMAN	zinc fingers and homeoboxes 1	243					negative regulation of transcription, DNA-dependent	nucleus	protein binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			breast(3)|cervix(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(6)|liver(1)|lung(5)|ovary(1)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	29	Lung NSC(37;1.25e-09)|Ovarian(258;0.0154)		STAD - Stomach adenocarcinoma(47;0.00527)			AGTACTTGGATGTATTCTGTT	0.398000													6	52					0	0	0.001168	0	0
PITPNC1	26207	broad.mit.edu	37	17	65665757	65665757	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:65665757G>A	ENST00000580974.1	+	7	1292	c.596G>A	c.(595-597)aGa>aAa	p.R199K	PITPNC1_ENST00000581322.1_Missense_Mutation_p.R199K|PITPNC1_ENST00000335257.6_Missense_Mutation_p.R199K|PITPNC1_ENST00000299954.9_Missense_Mutation_p.R199K	NM_012417.3|NM_181671.2	NP_036549.2|NP_858057.1	Q9UKF7	PITC1_HUMAN	phosphatidylinositol transfer protein, cytoplasmic 1	199					signal transduction	cytoplasm	lipid binding|phosphatidylinositol transporter activity|protein binding			breast(1)|kidney(2)|large_intestine(3)|liver(2)|lung(4)|prostate(2)|skin(3)	17	all_cancers(12;3.03e-10)		BRCA - Breast invasive adenocarcinoma(8;2.08e-08)|Colorectal(3;0.198)			CTTCAGACCAGAGTGGAACAA	0.493000													3	13					0	0	0.004672	0	0
ARPC3	10094	broad.mit.edu	37	12	110883275	110883275	+	Nonsense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:110883275C>A	ENST00000228825.7	-	2	234	c.88G>T	c.(88-90)Gga>Tga	p.G30*	RP11-478C19.2_ENST00000550231.1_RNA|ARPC3_ENST00000471641.1_5'UTR	NM_001278556.1|NM_005719.2	NP_001265485.1|NP_005710.1	O15145	ARPC3_HUMAN	actin related protein 2/3 complex, subunit 3, 21kDa	30					cellular component movement|regulation of actin filament polymerization	Arp2/3 protein complex|cytoplasm	actin binding|structural constituent of cytoskeleton			lung(1)|ovary(1)	2						GGGGCAGGTCCTTTGAATTGA	0.408000													7	53					0.000157383	0.000184718	0.003080	1	0
FAM179B	23116	broad.mit.edu	37	14	45432036	45432036	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:45432036C>T	ENST00000361462.2	+	1	595	c.412C>T	c.(412-414)Cgg>Tgg	p.R138W	FAM179B_ENST00000361577.3_Missense_Mutation_p.R138W|FAM179B_ENST00000382233.2_Missense_Mutation_p.R138W			Q9Y4F4	F179B_HUMAN	family with sequence similarity 179, member B	138							binding			endometrium(4)|kidney(5)|large_intestine(12)|lung(16)|prostate(2)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	45						AGCTTTGTATCGGGCACTGGG	0.632000													6	59					0	0	0.001168	0	0
RP11-403I13.8	0	broad.mit.edu	37	1	149288612	149288612	+	RNA	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:149288612G>C	ENST00000433084.1	+	0	1162																											GCTTCTTTCCGTTGCAGAGAA	0.652000													2	3					0	0	0.004672	0	0
HDAC9	9734	broad.mit.edu	37	7	18869166	18869166	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:18869166G>C	ENST00000406451.3	+	19	2602	c.2452G>C	c.(2452-2454)Gat>Cat	p.D818H	HDAC9_ENST00000441542.2_Missense_Mutation_p.D821H|HDAC9_ENST00000401921.1_Missense_Mutation_p.D777H|HDAC9_ENST00000432645.2_Missense_Mutation_p.D818H	NM_178423.1|NM_178425.2	NP_848510.1|NP_848512.1	Q9UKV0	HDAC9_HUMAN	histone deacetylase 9	818	Histone deacetylase.				B cell differentiation|cellular response to insulin stimulus|heart development|histone H3 deacetylation|histone H4 deacetylation|inflammatory response|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transcription, DNA-dependent|peptidyl-lysine deacetylation|positive regulation of cell migration involved in sprouting angiogenesis|regulation of skeletal muscle fiber development|transcription, DNA-dependent	cytoplasm|histone deacetylase complex|histone methyltransferase complex|transcription factor complex	histone deacetylase activity (H3-K16 specific)|histone deacetylase binding|NAD-dependent histone deacetylase activity (H3-K14 specific)|NAD-dependent histone deacetylase activity (H3-K9 specific)|NAD-dependent histone deacetylase activity (H4-K16 specific)|protein binding|protein kinase C binding|repressing transcription factor binding|transcription corepressor activity			breast(3)|central_nervous_system(4)|cervix(2)|endometrium(3)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(18)|liver(2)|lung(37)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(2)	82	all_lung(11;0.187)				Valproic Acid(DB00313)	ATTGATTGTAGATCTGGTATG	0.383000													6	68					0	0	0.001168	0	0
LRBA	987	broad.mit.edu	37	4	151773336	151773336	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:151773336C>T	ENST00000535741.1	-	23	3999	c.3526G>A	c.(3526-3528)Gat>Aat	p.D1176N	LRBA_ENST00000510413.1_Missense_Mutation_p.D1176N|LRBA_ENST00000507224.1_Missense_Mutation_p.D1176N|LRBA_ENST00000357115.3_Missense_Mutation_p.D1176N			P50851	LRBA_HUMAN	LPS-responsive vesicle trafficking, beach and anchor containing	1176						endoplasmic reticulum|Golgi apparatus|integral to membrane|lysosome|plasma membrane	protein binding			breast(6)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(9)|large_intestine(20)|lung(32)|ovary(4)|prostate(6)|skin(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	91	all_hematologic(180;0.151)					ATTCCAGAATCTTTAGAATCT	0.368000													4	108					0	0	0.009096	0	0
PCDHB10	56126	broad.mit.edu	37	5	140572893	140572893	+	Silent	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:140572893C>A	ENST00000239446.4	+	1	952	c.768C>A	c.(766-768)ccC>ccA	p.P256P		NM_018930.3	NP_061753.1	Q9UN67	PCDBA_HUMAN		256	Cadherin 3.				calcium-dependent cell-cell adhesion|homophilic cell adhesion|synapse assembly|synaptic transmission	integral to membrane|plasma membrane	calcium ion binding			breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(4)|large_intestine(14)|lung(30)|ovary(4)|prostate(5)|skin(3)|upper_aerodigestive_tract(4)|urinary_tract(2)	76			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			AAAACAGCCCCATTGGGTTCC	0.473000													7	59					2.17888e-05	2.66972e-05	0.006214	1	0
CHDC2	286464	broad.mit.edu	37	X	36091390	36091390	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:36091390G>A	ENST00000378660.1	+	4	513	c.325G>A	c.(325-327)Gag>Aag	p.E109K	CHDC2_ENST00000313548.4_Missense_Mutation_p.E109K					calponin homology domain containing 2																		CTACTTTTTTGAGAAGGTTGT	0.418000													5	37					0	0	0.001984	0	0
PDZD2	23037	broad.mit.edu	37	5	32072373	32072373	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:32072373G>A	ENST00000438447.1	+	17	3063	c.2675G>A	c.(2674-2676)gGa>gAa	p.G892E	PDZD2_ENST00000282493.3_Missense_Mutation_p.G892E			O15018	PDZD2_HUMAN	PDZ domain containing 2	892					cell adhesion	cell-cell junction|endoplasmic reticulum|extracellular region|nucleus				NS(2)|breast(4)|central_nervous_system(5)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(31)|lung(58)|ovary(6)|prostate(2)|skin(8)|stomach(1)|upper_aerodigestive_tract(4)|urinary_tract(1)	148						GATCACCCGGGAAGTGGCTGC	0.607000													4	36					0	0	0.009096	0	0
PCDHA13	56136	broad.mit.edu	37	5	140263970	140263970	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:140263970C>T	ENST00000289272.2	+	1	2117	c.2117C>T	c.(2116-2118)gCg>gTg	p.A706V	PCDHA6_ENST00000529310.1_Intron|PCDHA4_ENST00000530339.1_Intron|PCDHA1_ENST00000394633.3_Intron|PCDHA10_ENST00000506939.2_Intron|PCDHA1_ENST00000504120.2_Intron|PCDHA4_ENST00000512229.2_Intron|PCDHA10_ENST00000307360.5_Intron|PCDHA9_ENST00000532602.1_Intron|PCDHA5_ENST00000529619.1_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA3_ENST00000522353.2_Intron|PCDHA7_ENST00000525929.1_Intron|PCDHA13_ENST00000409494.1_Missense_Mutation_p.A706V|PCDHA8_ENST00000531613.1_Intron|PCDHA5_ENST00000529859.1_Intron|PCDHA6_ENST00000527624.1_Intron|PCDHA12_ENST00000398631.2_Intron|PCDHA11_ENST00000398640.2_Intron	NM_018904.2|NM_031865.1	NP_061727.1|NP_114071.1														NS(1)|biliary_tract(2)|breast(3)|central_nervous_system(2)|cervix(2)|endometrium(11)|haematopoietic_and_lymphoid_tissue(7)|kidney(2)|large_intestine(18)|liver(3)|lung(23)|ovary(4)|prostate(6)|skin(7)|upper_aerodigestive_tract(2)|urinary_tract(2)	95			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GCCATCTGCGCGGTGTCCAGC	0.657000													14	95					0	0	0.016723	0	0
CCT7	10574	broad.mit.edu	37	2	73471671	73471671	+	Splice_Site	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:73471671G>A	ENST00000539919.1	+	7	685		c.e7-1		CCT7_ENST00000538797.1_Splice_Site|CCT7_ENST00000258091.5_Splice_Site|CCT7_ENST00000473786.1_Splice_Site|CCT7_ENST00000540468.1_Splice_Site|CCT7_ENST00000537131.1_Splice_Site|CCT7_ENST00000398422.2_Intron	NM_001166285.1	NP_001159757.1	Q99832	TCPH_HUMAN	chaperonin containing TCP1, subunit 7 (eta)						'de novo' posttranslational protein folding		ATP binding|unfolded protein binding			breast(1)|cervix(1)|endometrium(1)|lung(3)|stomach(1)	7						TTGTGTCCCAGGGAGCAGAGG	0.493000													3	40					0	0	0.009096	0	0
NFKBID	84807	broad.mit.edu	37	19	36381356	36381356	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:36381356C>A	ENST00000396901.1	-	10	1216	c.643G>T	c.(643-645)Gtg>Ttg	p.V215L	NFKBID_ENST00000352614.2_Missense_Mutation_p.V367L|NFKBID_ENST00000606253.1_Missense_Mutation_p.V215L|NFKBID_ENST00000340950.2_Missense_Mutation_p.V52L	NM_139239.1	NP_640332.1	Q8NI38	IKBD_HUMAN	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, delta	215					inflammatory response	nucleus				breast(1)|cervix(1)|endometrium(2)|large_intestine(2)|lung(6)|ovary(1)|urinary_tract(1)	14						GCAGCCTGCACGGCCAAGTGC	0.612000													6	100					8.12818e-05	9.64141e-05	0.001984	1	0
PHF1	5252	broad.mit.edu	37	6	33382864	33382864	+	Nonsense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:33382864C>T	ENST00000374512.3	+	12	1442	c.1171C>T	c.(1171-1173)Caa>Taa	p.Q391*	PHF1_ENST00000374516.3_Silent_p.R394R	NM_002636.4	NP_002627.1	O43189	PHF1_HUMAN	PHD finger protein 1	469					chromatin modification	nucleus	nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(1)|lung(5)|ovary(2)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	19		Ovarian(999;0.0443)				CAGCAGTGCGCAATCAGCCCG	0.672000											OREG0017346	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	6	24					0	0	0.001168	0	0
ACAN	176	broad.mit.edu	37	15	89400400	89400400	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:89400400C>T	ENST00000439576.2	+	12	4958	c.4584C>T	c.(4582-4584)ctC>ctT	p.L1528L	ACAN_ENST00000561243.1_Silent_p.L1528L|ACAN_ENST00000559004.1_Silent_p.L1528L|ACAN_ENST00000352105.7_Silent_p.L1528L	NM_013227.3	NP_037359.3	E7EX88	E7EX88_HUMAN	aggrecan	1528					cell adhesion		hyaluronic acid binding|sugar binding			NS(1)|central_nervous_system(4)|cervix(1)|endometrium(3)|kidney(4)|large_intestine(15)|liver(2)|lung(40)|ovary(2)|prostate(5)|skin(5)|stomach(8)|upper_aerodigestive_tract(1)|urinary_tract(2)	93	Lung NSC(78;0.0392)|all_lung(78;0.077)		BRCA - Breast invasive adenocarcinoma(143;0.146)			TCAGCAGGCTCCCTTCTGGAG	0.502000													4	30					0	0	0.009096	0	0
DNAH2	146754	broad.mit.edu	37	17	7719956	7719956	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:7719956G>T	ENST00000572933.1	+	64	11257	c.9797G>T	c.(9796-9798)cGc>cTc	p.R3266L	DNAH2_ENST00000389173.2_Missense_Mutation_p.R3266L			Q9P225	DYH2_HUMAN	dynein, axonemal, heavy chain 2	3266	Stalk (By similarity).				ciliary or flagellar motility|microtubule-based movement	axonemal dynein complex|cilium axoneme|cytoplasm|microtubule	ATP binding|ATPase activity|microtubule motor activity			NS(3)|breast(11)|central_nervous_system(1)|cervix(3)|endometrium(18)|haematopoietic_and_lymphoid_tissue(2)|kidney(16)|large_intestine(53)|liver(2)|lung(49)|ovary(7)|prostate(7)|skin(15)|upper_aerodigestive_tract(1)|urinary_tract(1)	189		all_cancers(10;4.66e-07)|Prostate(122;0.081)				GAGGAGCTTCGCAAGAAGTCT	0.537000													22	215					2.89027e-11	4.00329e-11	0.014323	1	0
PCDHB7	56129	broad.mit.edu	37	5	140553607	140553607	+	Silent	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:140553607C>A	ENST00000231137.3	+	1	1365	c.1191C>A	c.(1189-1191)gtC>gtA	p.V397V		NM_018940.2	NP_061763.1	Q9Y5E2	PCDB7_HUMAN		397	Cadherin 4.				calcium-dependent cell-cell adhesion|homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			NS(2)|breast(2)|central_nervous_system(1)|endometrium(10)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(20)|lung(54)|ovary(5)|prostate(7)|skin(7)|upper_aerodigestive_tract(4)|urinary_tract(1)	119			KIRC - Kidney renal clear cell carcinoma(527;0.00185)|Kidney(363;0.00339)			AGCCATCTGTCGAAAACTTCT	0.493000													9	65					2.17888e-05	2.66972e-05	0.006214	1	0
NPHS1	4868	broad.mit.edu	37	19	36334405	36334405	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:36334405A>T	ENST00000378910.5	-	17	2302	c.2303T>A	c.(2302-2304)aTc>aAc	p.I768N	NPHS1_ENST00000353632.6_Missense_Mutation_p.I768N	NM_004646.3	NP_004637.1	O60500	NPHN_HUMAN	nephrosis 1, congenital, Finnish type (nephrin)	768	Ig-like C2-type 7.				cell adhesion|excretion|muscle organ development	integral to plasma membrane				NS(2)|breast(1)|cervix(3)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(16)|liver(1)|lung(26)|ovary(5)|prostate(1)|skin(7)|upper_aerodigestive_tract(1)|urinary_tract(1)	74	all_lung(56;7.14e-07)|Lung NSC(56;1.12e-06)|Esophageal squamous(110;0.162)		LUSC - Lung squamous cell carcinoma(66;0.0515)			GCCCGGGAGGATGGGATTGGC	0.567000													15	114					0	0	0.006122	0	0
OR5D18	219438	broad.mit.edu	37	11	55587308	55587308	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:55587308C>A	ENST00000333976.4	+	1	223	c.203C>A	c.(202-204)tCc>tAc	p.S68Y		NM_001001952.1	NP_001001952.1	Q8NGL1	OR5DI_HUMAN	olfactory receptor, family 5, subfamily D, member 18	68					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			NS(2)|breast(1)|endometrium(3)|large_intestine(6)|lung(33)|ovary(1)|prostate(3)|skin(3)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	55		all_epithelial(135;0.208)				AGCCAACTCTCCTTTGTGGAT	0.413000													15	221					5.03518e-11	6.93115e-11	0.007413	1	0
MAP3K4	4216	broad.mit.edu	37	6	161527689	161527689	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:161527689G>T	ENST00000392142.4	+	20	4148	c.4000G>T	c.(4000-4002)Gtt>Ttt	p.V1334F	MAP3K4_ENST00000366919.2_Missense_Mutation_p.V1284F|MAP3K4_ENST00000366920.2_Missense_Mutation_p.V1330F|MAP3K4_ENST00000348824.7_Missense_Mutation_p.V1280F	NM_005922.2	NP_005913.2	Q9Y6R4	M3K4_HUMAN	mitogen-activated protein kinase kinase kinase 4	1334					activation of MAPKK activity|JNK cascade|positive regulation of JUN kinase activity	perinuclear region of cytoplasm	ATP binding|MAP kinase kinase kinase activity|metal ion binding|protein binding			breast(6)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(20)|lung(28)|ovary(3)|skin(2)|stomach(1)	77		Breast(66;0.000776)|Ovarian(120;0.0367)|Prostate(117;0.0771)		OV - Ovarian serous cystadenocarcinoma(65;1.85e-18)|BRCA - Breast invasive adenocarcinoma(81;3.04e-05)		TGTTATGCACGTTGGCTTGAG	0.393000													6	106					0.00307968	0.00339984	0.003080	1	0
ZKSCAN4	387032	broad.mit.edu	37	6	28213679	28213679	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:28213679A>G	ENST00000377294.2	-	5	1096	c.853T>C	c.(853-855)Tgc>Cgc	p.C285R	ZKSCAN4_ENST00000423974.2_Missense_Mutation_p.C130R	NM_019110.3	NP_061983.2	Q969J2	ZKSC4_HUMAN	zinc finger with KRAB and SCAN domains 4	285	KRAB.				viral reproduction	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(2)|large_intestine(2)|lung(10)|ovary(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	18						CTCAGGTGGCATATCTTCCCA	0.488000													8	102					0	0	0.004482	0	0
GPR115	221393	broad.mit.edu	37	6	47681878	47681878	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:47681878G>T	ENST00000283303.2	+	6	1155	c.897G>T	c.(895-897)ggG>ggT	p.G299G	GPR115_ENST00000371220.1_Silent_p.G356G|GPR115_ENST00000327753.3_Silent_p.G299G	NM_153838.3	NP_722580.3	Q8IZF3	GP115_HUMAN	G protein-coupled receptor 115	299					neuropeptide signaling pathway	integral to membrane|plasma membrane	G-protein coupled receptor activity			NS(1)|breast(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(7)|lung(24)|ovary(3)|pancreas(1)|prostate(1)|skin(5)|upper_aerodigestive_tract(2)	52						CAACCTTGGGGGCTATCCTGA	0.468000													4	33					0.00909568	0.00979873	0.009096	1	0
KLF7	8609	broad.mit.edu	37	2	207953272	207953272	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:207953272C>A	ENST00000309446.6	-	3	1143	c.767G>T	c.(766-768)tGt>tTt	p.C256F	KLF7_ENST00000412414.2_Missense_Mutation_p.C228F|KLF7_ENST00000423015.1_Missense_Mutation_p.V189L|KLF7_ENST00000458272.1_Missense_Mutation_p.C66F|KLF7_ENST00000467833.1_5'UTR|KLF7_ENST00000421199.1_Missense_Mutation_p.C223F	NM_003709.3	NP_003700.1	O75840	KLF7_HUMAN	Kruppel-like factor 7 (ubiquitous)	256					regulation of transcription from RNA polymerase II promoter	nucleus	DNA binding|sequence-specific DNA binding transcription factor activity|transcription coactivator activity|zinc ion binding			breast(1)|central_nervous_system(1)|large_intestine(3)|liver(1)|lung(4)|skin(1)	11				LUSC - Lung squamous cell carcinoma(261;0.0856)|Lung(261;0.166)|Epithelial(149;0.173)		ACGCCACTCACATCCCTCCCA	0.517000													6	122					0.00116845	0.00131598	0.001168	1	0
RFWD2	64326	broad.mit.edu	37	1	175956199	175956199	+	Silent	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:175956199A>T	ENST00000367669.3	-	18	2527	c.2013T>A	c.(2011-2013)ctT>ctA	p.L671L	RFWD2_ENST00000308769.8_Silent_p.L647L	NM_022457.5	NP_071902.2	Q8NHY2	RFWD2_HUMAN	ring finger and WD repeat domain 2, E3 ubiquitin protein ligase	671					DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	centrosome|cytosol|focal adhesion|nuclear speck	protein binding|ubiquitin-protein ligase activity|zinc ion binding			endometrium(1)|kidney(2)|large_intestine(5)|lung(17)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	30						AAGTCTTAGAAAGTCCTTTAT	0.313000													8	69					0	0	0.006214	0	0
F5	2153	broad.mit.edu	37	1	169526045	169526045	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:169526045G>T	ENST00000367796.3	-	6	992	c.791C>A	c.(790-792)cCa>cAa	p.P264Q	F5_ENST00000546081.1_Missense_Mutation_p.P127Q|F5_ENST00000367797.3_Missense_Mutation_p.P264Q			P12259	FA5_HUMAN	coagulation factor V (proaccelerin, labile factor)	264	F5/8 type A 1.|Plastocyanin-like 2.				cell adhesion|platelet activation|platelet degranulation	plasma membrane|platelet alpha granule lumen	copper ion binding|oxidoreductase activity			NS(1)|breast(4)|central_nervous_system(4)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(24)|lung(55)|ovary(3)|prostate(4)|skin(5)|stomach(1)|upper_aerodigestive_tract(7)|urinary_tract(1)	128	all_hematologic(923;0.208)				Drotrecogin alfa(DB00055)	GAATAATTCTGGCCCCGAGCT	0.488000													16	35					3.52763e-06	4.54718e-06	0.004990	1	0
COL5A3	50509	broad.mit.edu	37	19	10079135	10079135	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:10079135G>T	ENST00000264828.3	-	59	4325	c.4240C>A	c.(4240-4242)Ccg>Acg	p.P1414T		NM_015719.3	NP_056534.2	P25940	CO5A3_HUMAN	collagen, type V, alpha 3	1414	Triple-helical region.				collagen fibril organization|skin development	collagen type V	collagen binding|extracellular matrix structural constituent			NS(2)|breast(3)|central_nervous_system(2)|endometrium(11)|kidney(23)|large_intestine(12)|liver(2)|lung(35)|ovary(8)|prostate(5)|skin(10)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	116			Epithelial(33;7.11e-05)			GCTTCTCCCGGGGGGCCAATG	0.597000													3	37					0.00024832	0.000288413	0.009096	1	0
COL13A1	1305	broad.mit.edu	37	10	71712696	71712696	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:71712696C>A	ENST00000356340.3	+	37	2620	c.2084C>A	c.(2083-2085)gCg>gAg	p.A695E	COL13A1_ENST00000398964.3_Missense_Mutation_p.A666E|COL13A1_ENST00000398973.3_Missense_Mutation_p.A669E|COL13A1_ENST00000398972.3_Missense_Mutation_p.A681E|COL13A1_ENST00000522165.1_Missense_Mutation_p.A664E|COL13A1_ENST00000398971.3_Missense_Mutation_p.A680E|COL13A1_ENST00000398968.3_Missense_Mutation_p.A676E|COL13A1_ENST00000398969.3_Missense_Mutation_p.A623E|COL13A1_ENST00000520267.1_Missense_Mutation_p.A623E|COL13A1_ENST00000357811.3_Missense_Mutation_p.A661E|COL13A1_ENST00000520133.1_Intron|COL13A1_ENST00000398978.3_Missense_Mutation_p.A695E|COL13A1_ENST00000517713.1_Missense_Mutation_p.A646E|COL13A1_ENST00000398974.3_Missense_Mutation_p.A683E|COL13A1_ENST00000398966.3_Missense_Mutation_p.A673E|COL13A1_ENST00000354547.3_Missense_Mutation_p.A673E			Q5TAT6	CODA1_HUMAN	collagen, type XIII, alpha 1	695	Triple-helical region 3 (COL3).				cell differentiation|cell-cell adhesion|cell-matrix adhesion|endochondral ossification|morphogenesis of a branching structure	collagen type XIII|integral to membrane	extracellular matrix structural constituent|heparin binding|protein binding			endometrium(5)|large_intestine(3)|lung(15)|ovary(1)|prostate(2)|skin(1)|urinary_tract(1)	28					Atorvastatin(DB01076)|Simvastatin(DB00641)	GACCAAGGAGCGCCTGGATTA	0.438000													5	61					0.000602214	0.000692236	0.014758	1	0
NAA25	80018	broad.mit.edu	37	12	112525588	112525588	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:112525588G>C	ENST00000261745.4	-	4	549	c.301C>G	c.(301-303)Ctt>Gtt	p.L101V		NM_024953.3	NP_079229.2	Q14CX7	NAA25_HUMAN	N(alpha)-acetyltransferase 25, NatB auxiliary subunit	101						cytoplasm	protein binding			autonomic_ganglia(1)|breast(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(10)|liver(1)|lung(14)|ovary(1)|pancreas(1)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(4)	46						GCCTCATAAAGTTTTGTAACT	0.363000													10	59					0	0	0.008291	0	0
FAM47A	158724	broad.mit.edu	37	X	34149052	34149052	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:34149052C>T	ENST00000346193.3	-	1	1395	c.1344G>A	c.(1342-1344)cgG>cgA	p.R448R		NM_203408.3	NP_981953.2	Q5JRC9	FA47A_HUMAN	family with sequence similarity 47, member A	448										NS(1)|biliary_tract(1)|breast(2)|central_nervous_system(1)|endometrium(9)|kidney(5)|large_intestine(17)|lung(44)|ovary(5)|prostate(2)|skin(4)|upper_aerodigestive_tract(4)|urinary_tract(2)	97						TTTTCTTCACCCGGGCCTCAC	0.562000													6	35					0	0	0.001168	0	0
CHDC2	286464	broad.mit.edu	37	X	36091419	36091419	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:36091419G>C	ENST00000378660.1	+	4	542	c.354G>C	c.(352-354)tgG>tgC	p.W118C	CHDC2_ENST00000313548.4_Missense_Mutation_p.W118C					calponin homology domain containing 2																		CACAGACCTGGTTCAGTCTCT	0.408000													4	44					0	0	0.014758	0	0
MAGEC3	139081	broad.mit.edu	37	X	140969493	140969493	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:140969493C>T	ENST00000298296.1	+	4	820	c.820C>T	c.(820-822)Cgc>Tgc	p.R274C	MAGEC3_ENST00000443323.2_Intron|MAGEC3_ENST00000448920.1_Intron|MAGEC3_ENST00000536088.1_Intron	NM_138702.1	NP_619647.1	Q8TD91	MAGC3_HUMAN	melanoma antigen family C, 3	274	MAGE 1.									NS(2)|breast(3)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(3)|kidney(2)|large_intestine(6)|liver(1)|lung(32)|ovary(1)|prostate(1)|skin(5)|stomach(1)|urinary_tract(2)	69	Acute lymphoblastic leukemia(192;6.56e-05)					GCCCCAGAACCGCCTCCTGAT	0.502000													9	77					0	0	0.004482	0	0
LOC220729	220729	broad.mit.edu	37	3	197348674	197348674	+	RNA	SNP	A	A	G	rs144273946	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:197348674A>G	ENST00000418868.1	-	0	585					NR_003266.2																						GGCTCTGTCCACCAAATGCAC	0.478000													3	59					0	0	0.004672	0	0
OTOGL	283310	broad.mit.edu	37	12	80661101	80661101	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:80661101G>A	ENST00000458043.2	+	21	2438	c.2432G>A	c.(2431-2433)gGc>gAc	p.G811D	OTOGL_ENST00000547103.1_Missense_Mutation_p.G811D	NM_173591.3	NP_775862.3			otogelin-like											breast(1)|endometrium(3)|kidney(2)|large_intestine(2)|lung(14)|prostate(1)	23						ACACCCTCGGGCTTATGGTAG	0.333000													5	14					0	0	0.001168	0	0
UACA	55075	broad.mit.edu	37	15	70961491	70961491	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:70961491C>T	ENST00000322954.6	-	16	1717	c.1532G>A	c.(1531-1533)gGt>gAt	p.G511D	UACA_ENST00000539319.1_Missense_Mutation_p.G402D|UACA_ENST00000560441.1_Missense_Mutation_p.G496D|UACA_ENST00000379983.2_Missense_Mutation_p.G498D	NM_018003.2	NP_060473.2	Q9BZF9	UACA_HUMAN	uveal autoantigen with coiled-coil domains and ankyrin repeats	511						cytoskeleton|extracellular region				breast(2)|endometrium(7)|kidney(4)|large_intestine(13)|lung(17)|ovary(2)|pancreas(1)|prostate(2)|skin(2)	50						TTTAACTTTACCTTCTGACTC	0.398000													33	217					0	0	0.012213	0	0
F13A1	2162	broad.mit.edu	37	6	6175039	6175039	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:6175039G>A	ENST00000264870.3	-	12	1786	c.1521C>T	c.(1519-1521)ctC>ctT	p.L507L		NM_000129.3	NP_000120.2	P00488	F13A_HUMAN	coagulation factor XIII, A1 polypeptide	507					peptide cross-linking|platelet activation|platelet degranulation	extracellular region|platelet alpha granule lumen	acyltransferase activity|metal ion binding|protein-glutamine gamma-glutamyltransferase activity			NS(1)|autonomic_ganglia(1)|breast(2)|central_nervous_system(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(10)|lung(37)|ovary(2)|pancreas(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	62	Ovarian(93;0.0816)	all_hematologic(90;0.152)			L-Glutamine(DB00130)	CTTCTGTGTTGAGGGGCTTTT	0.463000													3	39					0	0	0.014758	0	0
RP11-252A24.2	0	broad.mit.edu	37	16	74387769	74387769	+	RNA	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:74387769C>T	ENST00000429810.2	-	0	474																											TGGCAGTGCTCAGGATGCCAG	0.498000													7	39					0	0	0.001984	0	0
UFD1L	7353	broad.mit.edu	37	22	19463058	19463058	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:19463058C>T	ENST00000263202.9	-	2	200	c.71G>A	c.(70-72)cGc>cAc	p.R24H	UFD1L_ENST00000360834.4_Missense_Mutation_p.R24H|UFD1L_ENST00000484101.1_5'UTR|UFD1L_ENST00000399523.1_Missense_Mutation_p.R24H	NM_001035247.2|NM_005659.6	NP_001030324.2|NP_005650.2	Q92890	UFD1_HUMAN	ubiquitin fusion degradation 1 like (yeast)	24					skeletal system development|ubiquitin-dependent protein catabolic process	cytosol|nucleus	protein binding|ubiquitin-specific protease activity			large_intestine(3)|upper_aerodigestive_tract(1)	4	Colorectal(54;0.0993)					AGAGAAGCAGCGGTACTGTGT	0.438000													9	72					0	0	0.008291	0	0
RRN3P2	653390	broad.mit.edu	37	16	29110458	29110458	+	RNA	SNP	T	T	C	rs151074589	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:29110458T>C	ENST00000564580.1	+	0	1131																		p.W375R(25)									GAATTTTGAGTGGATAGTGAT	0.328000													3	24					0	0	0.004672	0	0
FGA	2243	broad.mit.edu	37	4	155507769	155507769	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:155507769C>G	ENST00000302053.3	-	5	890	c.812G>C	c.(811-813)cGa>cCa	p.R271P	FGA_ENST00000403106.3_Missense_Mutation_p.R271P	NM_000508.3	NP_000499.1	P02671	FIBA_HUMAN	fibrinogen alpha chain	271					platelet activation|platelet degranulation|protein polymerization|response to calcium ion|signal transduction	external side of plasma membrane|fibrinogen complex|platelet alpha granule lumen	eukaryotic cell surface binding|protein binding, bridging|receptor binding			NS(1)|breast(5)|central_nervous_system(2)|cervix(1)|endometrium(6)|kidney(2)|large_intestine(14)|liver(2)|lung(20)|ovary(3)|pancreas(1)|prostate(8)|skin(1)|upper_aerodigestive_tract(1)|urinary_tract(6)	73	all_hematologic(180;0.215)	Renal(120;0.0458)			Alteplase(DB00009)|Anistreplase(DB00029)|Reteplase(DB00015)|Sucralfate(DB00364)|Tenecteplase(DB00031)	GGAGCCTCCTCGAGTAATCTC	0.537000													10	110					0	0	0.010729	0	0
VASP	7408	broad.mit.edu	37	19	46027906	46027906	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:46027906G>C	ENST00000245932.6	+	11	1391	c.1035G>C	c.(1033-1035)caG>caC	p.Q345H		NM_003370.3	NP_003361.1	P50552	VASP_HUMAN	vasodilator-stimulated phosphoprotein	345	2 X 15 AA tandem repeats of L-[EQ]-[KR]- [MV]-K-[EQ]-E-[IL]-[IL]-E-[AEV]-[FV]- [KRV]-[KQ]-E.|EVH2 block C.|EVH2.				axon guidance|cell junction assembly|T cell receptor signaling pathway	actin cytoskeleton|cytosol|filopodium membrane|focal adhesion|lamellipodium membrane	actin binding|profilin binding|SH3 domain binding			endometrium(1)|kidney(1)|large_intestine(3)|lung(9)|ovary(1)|prostate(1)|skin(2)	18		Ovarian(192;0.051)|all_neural(266;0.112)		OV - Ovarian serous cystadenocarcinoma(262;0.0145)|GBM - Glioblastoma multiforme(486;0.154)		CGGACCTACAGAGGGTGAAAC	0.557000													8	60					0	0	0.003080	0	0
SMEK2	57223	broad.mit.edu	37	2	55792108	55792108	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:55792108C>T	ENST00000272313.5	-	12	2077	c.1750G>A	c.(1750-1752)Gtt>Att	p.V584I	SMEK2_ENST00000407823.3_Missense_Mutation_p.V637I|SMEK2_ENST00000345102.5_Missense_Mutation_p.V669I	NM_020463.2	NP_065196.1	Q5MIZ7	P4R3B_HUMAN	SMEK homolog 2, suppressor of mek1 (Dictyostelium)	669						microtubule organizing center|nucleus	protein binding			kidney(1)|large_intestine(4)|liver(1)|lung(7)|ovary(1)|prostate(1)|skin(1)	16			LUSC - Lung squamous cell carcinoma(58;0.127)|Lung(47;0.132)			AATGTCTGAACATATTCAATC	0.299000													3	27					0	0	0.009096	0	0
ABCB10	23456	broad.mit.edu	37	1	229685163	229685163	+	Missense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:229685163G>C	ENST00000344517.4	-	2	578	c.536C>G	c.(535-537)aCg>aGg	p.T179R		NM_012089.2	NP_036221.2	Q9NRK6	ABCBA_HUMAN	ATP-binding cassette, sub-family B (MDR/TAP), member 10	179	ABC transmembrane type-1.					integral to mitochondrial membrane|mitochondrial inner membrane	ATP binding|oligopeptide-transporting ATPase activity			breast(3)|endometrium(2)|kidney(1)|large_intestine(3)|lung(18)|prostate(2)|skin(2)	31	Breast(184;0.143)|Ovarian(103;0.249)	Prostate(94;0.167)				ACTGGACATCGTGAGAAATCC	0.512000													9	46					0	0	0.004482	0	0
ADCY8	114	broad.mit.edu	37	8	131861916	131861916	+	Missense_Mutation	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:131861916A>T	ENST00000286355.5	-	10	4436	c.2344T>A	c.(2344-2346)Tat>Aat	p.Y782N	ADCY8_ENST00000377928.3_Intron	NM_001115.2	NP_001106.1	P40145	ADCY8_HUMAN	adenylate cyclase 8 (brain)	782					activation of adenylate cyclase activity by G-protein signaling pathway|activation of phospholipase C activity|activation of protein kinase A activity|cellular response to glucagon stimulus|energy reserve metabolic process|inhibition of adenylate cyclase activity by G-protein signaling pathway|nerve growth factor receptor signaling pathway|synaptic transmission|transmembrane transport|water transport	integral to membrane|membrane fraction|plasma membrane	ATP binding|calcium- and calmodulin-responsive adenylate cyclase activity|metal ion binding			NS(1)|breast(4)|central_nervous_system(2)|cervix(1)|endometrium(10)|kidney(5)|large_intestine(21)|lung(67)|pancreas(1)|prostate(3)|skin(12)|upper_aerodigestive_tract(5)|urinary_tract(2)	134	Esophageal squamous(12;0.00693)|Ovarian(258;0.00707)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.000538)			CGGGCCAAATAGGTCTCATTA	0.463000										HNSCC(32;0.087)			23	118					0	0	0.018920	0	0
IGLV9-49	28773	broad.mit.edu	37	22	22697799	22697799	+	RNA	SNP	A	A	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:22697799A>T	ENST00000427632.2	+	0	124																											CACCTTCTGCATCAGCCTCCC	0.597000											OREG0026357	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	3	21					0	0	0.004672	0	0
SPATA31D5P	347127	broad.mit.edu	37	9	84530644	84530644	+	RNA	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:84530644C>G	ENST00000527857.1	+	0	666					NR_026851.1																						CTTATTTTCACCCTCACCACT	0.532000													16	245					0	0	0.004007	0	0
AVL9	23080	broad.mit.edu	37	7	32598881	32598881	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:32598881G>A	ENST00000318709.4	+	10	1241	c.1020G>A	c.(1018-1020)gaG>gaA	p.E340E	AVL9_ENST00000404479.1_Silent_p.E340E|AVL9_ENST00000409301.1_Silent_p.E340E	NM_015060.1	NP_055875.1	Q8NBF6	AVL9_HUMAN	AVL9 homolog (S. cerevisiase)	340						integral to membrane				endometrium(3)|kidney(1)|large_intestine(3)|lung(7)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	18						GTGTCTTAGAGGACCCCAACT	0.443000													4	55					0	0	0.014758	0	0
SMG1	23049	broad.mit.edu	37	16	18883652	18883652	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:18883652G>A	ENST00000446231.2	-	15	2449	c.2037C>T	c.(2035-2037)atC>atT	p.I679I	SMG1_ENST00000389467.3_Silent_p.I679I			Q96Q15	SMG1_HUMAN	SMG1 phosphatidylinositol 3-kinase-related kinase	679	Interaction with SMG8 and SMG9.				DNA repair|mRNA export from nucleus|nuclear-transcribed mRNA catabolic process, nonsense-mediated decay|peptidyl-serine phosphorylation|phosphatidylinositol phosphorylation|protein autophosphorylation	cytoplasm|nucleus	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity			NS(2)|breast(8)|cervix(2)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(16)|lung(37)|ovary(1)|skin(1)|stomach(4)|urinary_tract(1)	92						GGCTACTAGAGATAAAGTGAT	0.338000													3	25					0	0	0.004672	0	0
TMEM117	84216	broad.mit.edu	37	12	44782164	44782164	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:44782164G>A	ENST00000266534.3	+	8	1381	c.1254G>A	c.(1252-1254)ttG>ttA	p.L418L	TMEM117_ENST00000551577.1_3'UTR|TMEM117_ENST00000536799.1_Silent_p.L314L|TMEM117_ENST00000546978.1_3'UTR	NM_032256.1	NP_115632.1	Q9H0C3	TM117_HUMAN	transmembrane protein 117	418						endoplasmic reticulum|integral to membrane				breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(4)|lung(14)|urinary_tract(1)	23	Lung SC(27;0.192)			GBM - Glioblastoma multiforme(48;0.124)		GACGATTTTTGAAAAATGAGC	0.408000													15	91					0	0	0.004990	0	0
ATP8B4	79895	broad.mit.edu	37	15	50226286	50226286	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:50226286C>A	ENST00000284509.6	-	15	1522	c.1381G>T	c.(1381-1383)Gat>Tat	p.D461Y	ATP8B4_ENST00000559829.1_Missense_Mutation_p.D461Y	NM_024837.2	NP_079113.2	Q8TF62	AT8B4_HUMAN	ATPase, class I, type 8B, member 4	461					ATP biosynthetic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			breast(6)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(14)|lung(27)|ovary(2)|pancreas(1)|prostate(1)|skin(7)|urinary_tract(1)	73		all_lung(180;0.00183)		all cancers(107;2.41e-07)|GBM - Glioblastoma multiforme(94;8.28e-05)		ACTTTGGGATCACCCATTTTA	0.418000													10	215					4.68919e-08	6.41527e-08	0.008291	1	0
SH3RF3	344558	broad.mit.edu	37	2	110015211	110015211	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:110015211G>A	ENST00000309415.6	+	4	1111	c.1111G>A	c.(1111-1113)Gat>Aat	p.D371N		NM_001099289.1	NP_001092759.1	Q8TEJ3	SH3R3_HUMAN	SH3 domain containing ring finger 3	371							zinc ion binding			endometrium(2)|kidney(1)|large_intestine(6)|liver(2)|lung(5)|ovary(2)	18						GCGGCGTGTGGATGGCAAGAA	0.607000													4	20					0	0	0.014758	0	0
ACHE	43	broad.mit.edu	37	7	100491143	100491143	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:100491143G>T	ENST00000302913.4	-	2	849	c.711C>A	c.(709-711)gcC>gcA	p.A237A	ACHE_ENST00000428317.1_Silent_p.A237A|ACHE_ENST00000411582.1_Silent_p.A237A|ACHE_ENST00000419336.2_Silent_p.A237A|ACHE_ENST00000241069.5_Silent_p.A237A|ACHE_ENST00000412389.1_Silent_p.A237A	NM_015831.2	NP_056646.1	P22303	ACES_HUMAN	acetylcholinesterase	237					acetylcholine catabolic process in synaptic cleft|amyloid precursor protein metabolic process|cell adhesion|cell proliferation|choline metabolic process|DNA replication|muscle organ development|neurotransmitter biosynthetic process|osteoblast development|positive regulation of protein secretion|regulation of axonogenesis|regulation of dendrite morphogenesis|response to wounding|synapse assembly	anchored to membrane|axon|basal lamina|cell junction|cell surface|dendrite|endoplasmic reticulum lumen|extracellular space|Golgi apparatus|neuromuscular junction|nucleus|perinuclear region of cytoplasm|postsynaptic membrane|presynaptic membrane|synaptic cleft	acetylcholine binding|acetylcholinesterase activity|beta-amyloid binding|carboxylesterase activity|cholinesterase activity|collagen binding|laminin-1 binding|protein homodimerization activity|serine hydrolase activity			large_intestine(3)|lung(7)|skin(3)|urinary_tract(3)	16	Lung NSC(181;0.041)|all_lung(186;0.0581)				Ambenonium(DB01122)|Atropine(DB00572)|Choline(DB00122)|Decamethonium(DB01245)|Demecarium bromide(DB00944)|Donepezil(DB00843)|Edrophonium(DB01010)|Ephedrine(DB01364)|Galantamine(DB00674)|Gallamine Triethiodide(DB00483)|Isoflurophate(DB00677)|Neostigmine(DB01400)|Physostigmine(DB00981)|Pyridostigmine(DB00545)|Rivastigmine(DB00989)|Tacrine(DB00382)|Tubocurarine(DB01199)	CCACCGAGGCGGCTCCCGCGC	0.701000													8	30					1.12685e-05	1.40384e-05	0.004482	1	0
DCBLD1	285761	broad.mit.edu	37	6	117846533	117846533	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:117846533G>T	ENST00000338728.5	+	5	641	c.521G>T	c.(520-522)tGc>tTc	p.C174F	DCBLD1_ENST00000296955.8_Missense_Mutation_p.C174F|DCBLD1_ENST00000368503.4_Missense_Mutation_p.C174F|GOPC_ENST00000467125.1_Intron			Q8N8Z6	DCBD1_HUMAN	discoidin, CUB and LCCL domain containing 1	174	LCCL.				cell adhesion	integral to membrane				breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(15)|ovary(1)|prostate(1)|stomach(1)|upper_aerodigestive_tract(1)	26		all_cancers(87;0.171)		GBM - Glioblastoma multiforme(226;0.0447)|OV - Ovarian serous cystadenocarcinoma(136;0.0921)|all cancers(137;0.125)		AGCAAATTCTGCCCAGCTGGT	0.303000													6	32					0.00116845	0.00131598	0.001168	1	0
EPHA4	2043	broad.mit.edu	37	2	222428866	222428866	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:222428866G>T	ENST00000281821.2	-	3	449	c.408C>A	c.(406-408)ttC>ttA	p.F136L	EPHA4_ENST00000409854.1_Missense_Mutation_p.F136L|EPHA4_ENST00000409938.1_Missense_Mutation_p.F136L|EPHA4_ENST00000392071.4_Missense_Mutation_p.F85L	NM_004438.3	NP_004429.1	P54764	EPHA4_HUMAN	EPH receptor A4	136						integral to plasma membrane	ATP binding|ephrin receptor activity			NS(1)|breast(1)|central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(9)|liver(1)|lung(21)|prostate(3)|skin(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	49		Renal(207;0.0183)		Epithelial(121;5.38e-09)|all cancers(144;2.47e-06)|LUSC - Lung squamous cell carcinoma(224;0.0115)|Lung(261;0.0154)		TCTCTCTGATGAAACGCTCTT	0.468000													10	72					0.000673444	0.000766214	0.008291	1	0
RPS27L	51065	broad.mit.edu	37	15	63447831	63447831	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:63447831C>T	ENST00000330964.5	-	3	611	c.215G>A	c.(214-216)aGa>aAa	p.R72K	RPS27L_ENST00000559763.1_5'UTR|RPS27L_ENST00000462430.1_Missense_Mutation_p.R88K|RPS27L_ENST00000455271.1_Missense_Mutation_p.R40K|RPS27L_ENST00000439025.1_Missense_Mutation_p.R72K|RPS27L_ENST00000411926.1_Missense_Mutation_p.R40K	NM_015920.3	NP_057004.1	Q71UM5	RS27L_HUMAN	ribosomal protein S27-like	72					DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis|DNA repair|mitotic cell cycle G1/S transition DNA damage checkpoint|positive regulation of anti-apoptosis|translation	nucleus|ribosome	caspase activator activity|metal ion binding|structural constituent of ribosome|translation activator activity			large_intestine(1)	1						TTCTGTGAGTCTGGCCTTTCC	0.413000													7	87					0	0	0.004482	0	0
MUC17	140453	broad.mit.edu	37	7	100683879	100683879	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:100683879C>T	ENST00000306151.4	+	3	9246	c.9182C>T	c.(9181-9183)cCt>cTt	p.P3061L		NM_001040105.1	NP_001035194.1	Q685J3	MUC17_HUMAN	mucin 17, cell surface associated	3061	59 X approximate tandem repeats.|Ser-rich.					extracellular region|integral to membrane|plasma membrane	extracellular matrix constituent, lubricant activity	p.P3061H(1)		NS(3)|breast(14)|central_nervous_system(2)|cervix(2)|endometrium(27)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(28)|lung(179)|ovary(19)|pancreas(1)|prostate(13)|skin(26)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(4)	343	Lung NSC(181;0.136)|all_lung(186;0.182)					GTGGCCATTCCTGAGGCTAGC	0.498000													13	151					0	0	0.008871	0	0
CHL1	10752	broad.mit.edu	37	3	423942	423942	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:423942G>A	ENST00000256509.2	+	17	2599	c.1957G>A	c.(1957-1959)Gac>Aac	p.D653N	CHL1-AS1_ENST00000417612.1_RNA|CHL1_ENST00000397491.2_Missense_Mutation_p.D637N	NM_001253387.1|NM_001253388.1|NM_006614.3	NP_001240316.1|NP_001240317.1|NP_006605.2	O00533	CHL1_HUMAN	cell adhesion molecule L1-like	637	Fibronectin type-III 1.				axon guidance|cell adhesion|signal transduction	integral to membrane|plasma membrane|proteinaceous extracellular matrix				NS(1)|central_nervous_system(5)|endometrium(11)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(25)|lung(31)|ovary(1)|prostate(4)|skin(10)|stomach(1)	93		all_cancers(2;1.14e-06)|all_epithelial(2;0.00367)|all_lung(1;0.061)|Lung NSC(2;0.201)		Epithelial(13;5.36e-06)|all cancers(10;1.4e-05)|OV - Ovarian serous cystadenocarcinoma(96;0.00323)|COAD - Colon adenocarcinoma(1;0.00925)|Colorectal(20;0.0198)		AGCTGGAGCTGACCACAACAG	0.413000													4	62					0	0	0.009096	0	0
KRAS	3845	broad.mit.edu	37	12	25398284	25398284	+	Missense_Mutation	SNP	C	C	A	rs121913529		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:25398284C>A	ENST00000311936.3	-	2	226	c.35G>T	c.(34-36)gGt>gTt	p.G12V	KRAS_ENST00000557334.1_Missense_Mutation_p.G12V|KRAS_ENST00000556131.1_Missense_Mutation_p.G12V|KRAS_ENST00000256078.4_Missense_Mutation_p.G12V	NM_004985.3	NP_004976.2	P01116	RASK_HUMAN	Kirsten rat sarcoma viral oncogene homolog	12			G -> A (in a colorectal cancer sample; somatic mutation).|G -> C (in lung carcinoma; somatic mutation).|G -> D (in pancreatic carcinoma, GASC and lung carcinoma; somatic mutation).|G -> R (in lung cancer and bladder cancer; somatic mutation).|G -> S (in lung carcinoma and GASC; somatic mutation).|G -> V (in lung carcinoma, pancreatic carcinoma, colon cancer and GASC; somatic mutation).		activation of MAPKK activity|axon guidance|blood coagulation|epidermal growth factor receptor signaling pathway|insulin receptor signaling pathway|leukocyte migration|nerve growth factor receptor signaling pathway|Ras protein signal transduction	plasma membrane	GTP binding|GTPase activity|protein binding	p.G12D(8562)|p.G12V(5775)|p.G12A(1407)|p.G12F(46)|p.G12L(8)|p.G12I(4)|p.G12E(3)|p.G12W(3)|p.G12Y(2)|p.G12fs*3(1)|p.G12C(1)|p.G12N(1)	UBE2L3/KRAS(2)	NS(6)|adrenal_gland(1)|autonomic_ganglia(3)|biliary_tract(532)|bone(2)|breast(32)|central_nervous_system(14)|cervix(50)|endometrium(411)|eye(4)|gastrointestinal_tract_(site_indeterminate)(7)|genital_tract(1)|haematopoietic_and_lymphoid_tissue(385)|kidney(8)|large_intestine(15267)|liver(29)|lung(3407)|oesophagus(16)|ovary(612)|pancreas(3739)|penis(1)|peritoneum(6)|prostate(96)|salivary_gland(6)|skin(45)|small_intestine(68)|soft_tissue(88)|stomach(207)|testis(17)|thymus(5)|thyroid(159)|upper_aerodigestive_tract(68)|urinary_tract(57)	25349	all_cancers(2;1e-35)|all_epithelial(2;1.97e-38)|all_lung(3;2.1e-23)|Lung NSC(3;1.16e-22)|Acute lymphoblastic leukemia(6;0.00231)|all_hematologic(7;0.00259)|Melanoma(3;0.0301)|Colorectal(261;0.11)|Ovarian(17;0.12)		OV - Ovarian serous cystadenocarcinoma(3;1.23e-21)|Epithelial(3;1.31e-20)|all cancers(3;5.45e-18)|STAD - Stomach adenocarcinoma(2;2.68e-05)			GCCTACGCCACCAGCTCCAAC	0.348000	G12A(KMS28BM_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(KPNSI9S_AUTONOMIC_GANGLIA)|G12A(MM1S_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(NCIH1573_LUNG)|G12A(NCIH2009_LUNG)|G12A(RERFLCAD1_LUNG)|G12A(RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12A(SW1116_LARGE_INTESTINE)|G12D(AGS_STOMACH)|G12D(ASPC1_PANCREAS)|G12D(COLO678_LARGE_INTESTINE)|G12D(HEC1A_ENDOMETRIUM)|G12D(HEC50B_ENDOMETRIUM)|G12D(HEYA8_OVARY)|G12D(HPAC_PANCREAS)|G12D(HPAFII_PANCREAS)|G12D(KARPAS620_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12D(KOPN8_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE)|G12D(KP4_PANCREAS)|G12D(L33_PANCREAS)|G12D(LS180_LARGE_INTESTINE)|G12D(LS513_LARGE_INTESTINE)|G12D(MCAS_OVARY)|G12D(PANC0203_PANCREAS)|G12D(PANC0403_PANCREAS)|G12D(PANC0504_PANCREAS)|G12D(PANC0813_PANCREAS)|G12D(PANC1_PANCREAS)|G12D(PK1_PANCREAS)|G12D(PK59_PANCREAS)|G12D(SKLU1_LUNG)|G12D(SNUC2A_LARGE_INTESTINE)|G12D(SU8686_PANCREAS)|G12D(SUIT2_PANCREAS)|G12D(SW1990_PANCREAS)|G12V(A498_KIDNEY)|G12V(CAPAN2_PANCREAS)|G12V(CFPAC1_PANCREAS)|G12V(COLO668_LUNG)|G12V(CORL23_LUNG)|G12V(DANG_PANCREAS)|G12V(HCC56_LARGE_INTESTINE)|G12V(HUPT4_PANCREAS)|G12V(KP3_PANCREAS)|G12V(LCLC97TM1_LUNG)|G12V(NCIH2444_LUNG)|G12V(NCIH441_LUNG)|G12V(NCIH727_LUNG)|G12V(PANC0327_PANCREAS)|G12V(PATU8902_PANCREAS)|G12V(PATU8988S_PANCREAS)|G12V(QGP1_PANCREAS)|G12V(RCM1_LARGE_INTESTINE)|G12V(RERFLCAD2_LUNG)|G12V(RKN_OVARY)|G12V(SH10TC_STOMACH)|G12V(SHP77_LUNG)|G12V(SNGM_ENDOMETRIUM)|G12V(SW403_LARGE_INTESTINE)|G12V(SW480_LARGE_INTESTINE)|G12V(SW620_LARGE_INTESTINE)|G12V(SW900_LUNG)|G12V(YAPC_PANCREAS)	119	Mis		"""pancreatic, colorectal, lung, thyroid, AML, others"""				Noonan syndrome;Cardiofaciocutaneous syndrome	TSP Lung(1;<1E-08)|Multiple Myeloma(2;<1E-6)			6	14					0.00198382	0.00222307	0.001984	1	0
POP1	10940	broad.mit.edu	37	8	99169980	99169980	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:99169980C>T	ENST00000401707.2	+	16	2637	c.2556C>T	c.(2554-2556)ttC>ttT	p.F852F	POP1_ENST00000349693.3_Silent_p.F852F	NM_001145860.1|NM_001145861.1	NP_001139332.1|NP_001139333.1	Q99575	POP1_HUMAN	processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)	852					tRNA 5'-leader removal|tRNA catabolic process	nucleolar ribonuclease P complex|ribonuclease MRP complex	identical protein binding|ribonuclease MRP activity|ribonuclease P activity			autonomic_ganglia(1)|breast(3)|endometrium(4)|large_intestine(9)|lung(15)|ovary(1)|upper_aerodigestive_tract(2)|urinary_tract(1)	36	Breast(36;1.78e-06)		OV - Ovarian serous cystadenocarcinoma(57;0.145)			TGGGCCACTTCCCCAGGGCCC	0.647000													4	82					0	0	0.009096	0	0
ACKR2	1238	broad.mit.edu	37	3	42906618	42906618	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:42906618C>T	ENST00000422265.1	+	3	799	c.624C>T	c.(622-624)ctC>ctT	p.L208L	KRBOX1_ENST00000426937.1_Intron|CYP8B1_ENST00000437102.1_Intron|ACKR2_ENST00000442925.1_Silent_p.L208L|ACKR2_ENST00000273145.2_Silent_p.L208L|ACKR2_ENST00000471537.1_Intron	NM_001296.4	NP_001287.2			atypical chemokine receptor 2																		TTTGGAAGCTCTTCCTCCGCT	0.522000													18	189					0	0	0.012319	0	0
GZMK	3003	broad.mit.edu	37	5	54329714	54329714	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:54329714C>A	ENST00000231009.2	+	5	825	c.755C>A	c.(754-756)aCt>aAt	p.T252N	CTD-2313F11.1_ENST00000595218.1_RNA	NM_002104.2	NP_002095.1	P49863	GRAK_HUMAN	granzyme K (granzyme 3; tryptase II)	252	Peptidase S1.				proteolysis	extracellular region	serine-type endopeptidase activity			autonomic_ganglia(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(7)|lung(4)	15		Lung NSC(810;4.08e-05)|Breast(144;0.0433)|Prostate(74;0.183)				AAATACCAGACTTGGATCAAA	0.408000													4	58					0.00024832	0.000288413	0.009096	1	0
STRIP1	85369	broad.mit.edu	37	1	110594385	110594385	+	Silent	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:110594385G>A	ENST00000369795.3	+	20	2164	c.2142G>A	c.(2140-2142)ctG>ctA	p.L714L	STRIP1_ENST00000369796.1_Silent_p.L619L	NM_033088.2	NP_149079.2			striatin interacting protein 1																		TCTATGTGCTGAAGCTGCTCA	0.532000													8	45					0	0	0.003080	0	0
IL1RL1	9173	broad.mit.edu	37	2	102957269	102957269	+	Silent	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:102957269C>A	ENST00000311734.2	+	5	930	c.591C>A	c.(589-591)acC>acA	p.T197T	IL1RL1_ENST00000233954.1_Silent_p.T197T|IL1RL1_ENST00000409584.1_Silent_p.T197T|IL1RL1_ENST00000393393.3_Silent_p.T197T|IL1RL1_ENST00000404917.2_Silent_p.T80T			Q01638	ILRL1_HUMAN	interleukin 1 receptor-like 1	197	Ig-like C2-type 2.				innate immune response	integral to membrane	interleukin-1 receptor activity|receptor signaling protein activity			NS(1)|central_nervous_system(1)|kidney(1)|large_intestine(3)|lung(5)|ovary(1)|skin(3)|urinary_tract(1)	16						TGACGGCGACCAGGTCCTTCA	0.433000													6	102					5.18039e-06	6.6013e-06	0.003080	1	0
INTS8	55656	broad.mit.edu	37	8	95888301	95888301	+	Splice_Site	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:95888301G>A	ENST00000523731.1	+	24	2821		c.e24-1		INTS8_ENST00000447247.1_Splice_Site	NM_017864.2	NP_060334.2	Q75QN2	INT8_HUMAN	integrator complex subunit 8						snRNA processing	integrator complex	protein binding			breast(3)|endometrium(3)|kidney(1)|large_intestine(9)|liver(1)|lung(9)|prostate(1)|upper_aerodigestive_tract(1)	28	Breast(36;1.05e-06)					TGTTAATGTAGGTGGCCATTT	0.294000													5	78					0	0	0.001984	0	0
PCED1A	64773	broad.mit.edu	37	20	2816935	2816935	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:2816935C>A	ENST00000360652.2	-	7	1369	c.867G>T	c.(865-867)gaG>gaT	p.E289D	PCED1A_ENST00000356872.3_Missense_Mutation_p.E238D	NM_022760.3	NP_073597.2			PC-esterase domain containing 1A																		GATGATTCATCTCTGCCCAGT	0.567000													12	84					2.27111e-07	3.05095e-07	0.013537	1	0
SEC14L3	266629	broad.mit.edu	37	22	30857437	30857437	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:30857437A>G	ENST00000403066.1	-	12	1047	c.764T>C	c.(763-765)aTc>aCc	p.I255T	SEC14L3_ENST00000215812.4_Missense_Mutation_p.I314T|SEC14L3_ENST00000415957.2_Missense_Mutation_p.I255T|SEC14L3_ENST00000402286.1_Missense_Mutation_p.I237T|SEC14L3_ENST00000540910.1_Missense_Mutation_p.I237T|SEC14L3_ENST00000539629.1_Missense_Mutation_p.I255T|SEC14L3_ENST00000401751.1_Missense_Mutation_p.I255T			Q9UDX4	S14L3_HUMAN	SEC14-like 3 (S. cerevisiae)	314						integral to membrane|intracellular	lipid binding|transporter activity			NS(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(4)|lung(3)|ovary(3)|pancreas(1)|skin(2)|urinary_tract(1)	19					Vitamin E(DB00163)	TCCGAAGCCGATGTCCGCACC	0.607000													4	47					0	0	0.001168	0	0
BRINP1	1620	broad.mit.edu	37	9	122004361	122004361	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:122004361C>A	ENST00000265922.3	-	4	1004	c.543G>T	c.(541-543)agG>agT	p.R181S	DBC1_ENST00000373964.2_Missense_Mutation_p.R181S	NM_014618.2	NP_055433.2	O60477	DBC1_HUMAN		181	MACPF.				cell cycle arrest|cell death	cytoplasm	protein binding			NS(1)|breast(3)|central_nervous_system(3)|endometrium(8)|kidney(2)|large_intestine(15)|liver(1)|lung(34)|ovary(3)|prostate(3)|skin(4)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	83						TCTCATGAAGCCTCCTCATGG	0.507000													5	82					3.59834e-05	4.36103e-05	0.001168	1	0
CSTB	1476	broad.mit.edu	37	21	45194582	45194582	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:45194582G>A	ENST00000291568.5	-	2	300	c.125C>T	c.(124-126)tCa>tTa	p.S42L		NM_000100.3	NP_000091.1	P04080	CYTB_HUMAN	cystatin B (stefin B)	42						cytoplasm|nucleolus	cysteine-type endopeptidase inhibitor activity|protease binding			lung(1)|prostate(1)	2				STAD - Stomach adenocarcinoma(101;0.168)		GCTCTTGAATGACACGGCCTT	0.537000													6	34					0	0	0.001984	0	0
MIEN1	84299	broad.mit.edu	37	17	37885794	37885794	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:37885794G>A	ENST00000394231.3	-	4	620	c.329C>T	c.(328-330)cCt>cTt	p.P110L	MIEN1_ENST00000577810.1_3'UTR|MIEN1_ENST00000474210.1_5'UTR|ERBB2_ENST00000584888.1_Intron			Q9BRT3	CQ037_HUMAN	migration and invasion enhancer 1	110					cell redox homeostasis	cytosol|membrane	selenium binding										GACGCAGGGAGGACGGCTGTT	0.557000													14	156					0	0	0.007413	0	0
SYNPO2	171024	broad.mit.edu	37	4	119952472	119952472	+	Missense_Mutation	SNP	A	A	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:119952472A>C	ENST00000307142.4	+	4	2738	c.2542A>C	c.(2542-2544)Aca>Cca	p.T848P	SYNPO2_ENST00000429713.2_Missense_Mutation_p.T848P|SYNPO2_ENST00000448416.2_Intron|SYNPO2_ENST00000434046.2_Missense_Mutation_p.T848P	NM_133477.2	NP_597734.2	Q9UMS6	SYNP2_HUMAN	synaptopodin 2	848						nucleus|Z disc	14-3-3 protein binding|actin binding|muscle alpha-actinin binding			breast(3)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(20)|lung(18)|ovary(2)|prostate(3)|skin(6)|upper_aerodigestive_tract(1)|urinary_tract(1)	64						AACAGTTTCCACACCAACAGT	0.527000													9	97					0	0	0.004482	0	0
EARS2	124454	broad.mit.edu	37	16	23541066	23541066	+	Splice_Site	SNP	T	T	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:23541066T>A	ENST00000449606.1	-	6	1251	c.1221_splice	c.e6+1	p.Q407_splice	EARS2_ENST00000564501.1_Splice_Site_p.Q407_splice|EARS2_ENST00000563232.1_Splice_Site_p.Q407_splice|EARS2_ENST00000563459.1_Splice_Site_p.Q407_splice|EARS2_ENST00000564987.1_5'UTR	NM_001083614.1	NP_001077083.1	Q5JPH6	SYEM_HUMAN	glutamyl-tRNA synthetase 2, mitochondrial	407					glutamyl-tRNA aminoacylation	mitochondrial matrix	ATP binding|glutamate-tRNA ligase activity|RNA binding			central_nervous_system(1)|endometrium(1)|lung(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	8				GBM - Glioblastoma multiforme(48;0.0353)	L-Glutamic Acid(DB00142)	ACACCACACCTGTCTCAGCAG	0.572000													9	67					0	0	0.004482	0	0
CSMD3	114788	broad.mit.edu	37	8	113323222	113323222	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:113323222C>A	ENST00000297405.5	-	50	8114	c.7870G>T	c.(7870-7872)Gtc>Ttc	p.V2624F	CSMD3_ENST00000343508.3_Missense_Mutation_p.V2584F|CSMD3_ENST00000455883.2_Missense_Mutation_p.V2520F|CSMD3_ENST00000352409.3_Missense_Mutation_p.V2554F	NM_198123.1	NP_937756.1	Q7Z407	CSMD3_HUMAN	CUB and Sushi multiple domains 3	2624	Sushi 14.					integral to membrane|plasma membrane				breast(7)|central_nervous_system(6)|endometrium(44)|haematopoietic_and_lymphoid_tissue(8)|kidney(36)|large_intestine(72)|liver(5)|lung(389)|ovary(24)|prostate(6)|skin(23)|upper_aerodigestive_tract(19)|urinary_tract(7)	646						CAGGCAGGGACTGGCGCATCC	0.433000										HNSCC(6;0.00088)|TCGA Ovarian(7;0.080)			6	71					8.12818e-05	9.64141e-05	0.001984	1	0
CDADC1	81602	broad.mit.edu	37	13	49841903	49841903	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr13:49841903A>G	ENST00000251108.6	+	5	821	c.708A>G	c.(706-708)atA>atG	p.I236M	CDADC1_ENST00000444959.1_Missense_Mutation_p.I38M	NM_001193478.1|NM_030911.3	NP_001180407.1|NP_112173.1	Q9BWV3	CDAC1_HUMAN	cytidine and dCMP deaminase domain containing 1	236							hydrolase activity|zinc ion binding			endometrium(3)|kidney(2)|large_intestine(6)|lung(4)|upper_aerodigestive_tract(1)	16		Lung NSC(96;0.000705)|Breast(56;0.0011)|Prostate(109;0.00446)|Hepatocellular(98;0.0556)|Glioma(44;0.236)	KIRC - Kidney renal clear cell carcinoma(9;0.206)	GBM - Glioblastoma multiforme(99;1.06e-08)|COAD - Colon adenocarcinoma(199;0.216)		AAGAAAGAATAAAAGAATATG	0.294000													5	27					0	0	0.014758	0	0
ZNF717	100131827	broad.mit.edu	37	3	75790824	75790824	+	Missense_Mutation	SNP	C	C	T	rs146969485	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:75790824C>T	ENST00000422325.1	-	3	443	c.121G>A	c.(121-123)Gat>Aat	p.D41N	ZNF717_ENST00000478296.1_5'UTR|ZNF717_ENST00000477374.1_Missense_Mutation_p.D41N|ZNF717_ENST00000491507.1_5'UTR|ZNF717_ENST00000400845.3_Missense_Mutation_p.D34N	NM_001128223.1	NP_001121695.1	C9JSV9	C9JSV9_HUMAN	zinc finger protein 717	41					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding			autonomic_ganglia(6)|endometrium(3)|lung(2)|ovary(1)|stomach(7)	19						CTCTGAGCATCATCCAGGTCC	0.527000													3	11					0	0	0.004672	0	0
PRKD3	23683	broad.mit.edu	37	2	37516584	37516584	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:37516584C>T	ENST00000379066.1	-	5	1394	c.632G>A	c.(631-633)cGt>cAt	p.R211H	PRKD3_ENST00000234179.2_Missense_Mutation_p.R211H			O94806	KPCD3_HUMAN	protein kinase D3	211					activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway|intracellular signal transduction	cytoplasm|membrane|nucleus	ATP binding|metal ion binding|protein binding|protein kinase C activity			breast(3)|central_nervous_system(2)|kidney(3)|large_intestine(8)|lung(9)|ovary(3)|prostate(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	33		all_hematologic(82;0.21)				ATTTGACAGACGTCTCTTTCT	0.408000													4	39					0	0	0.014758	0	0
OR6C3	254786	broad.mit.edu	37	12	55725897	55725897	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:55725897G>T	ENST00000379667.1	+	1	413	c.413G>T	c.(412-414)tGc>tTc	p.C138F		NM_054104.1	NP_473445.1	Q9NZP0	OR6C3_HUMAN	olfactory receptor, family 6, subfamily C, member 3	138					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			endometrium(3)|kidney(2)|large_intestine(2)|lung(1)|prostate(1)|skin(2)	11						AGGAAACTCTGCACTCTACTT	0.473000													21	183					3.5997e-14	5.04863e-14	0.014323	1	0
TRPM6	140803	broad.mit.edu	37	9	77354666	77354666	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:77354666C>A	ENST00000451710.3	-	33	5709	c.5472G>T	c.(5470-5472)gaG>gaT	p.E1824D	TRPM6_ENST00000361255.3_Missense_Mutation_p.E1815D|TRPM6_ENST00000360774.1_Missense_Mutation_p.E1820D|TRPM6_ENST00000449912.2_Missense_Mutation_p.E1815D|TRPM6_ENST00000376864.4_Missense_Mutation_p.E1824D|TRPM6_ENST00000376871.3_Missense_Mutation_p.E657D|TRPM6_ENST00000376872.3_Missense_Mutation_p.E775D			Q9BX84	TRPM6_HUMAN	transient receptor potential cation channel, subfamily M, member 6	1820	Alpha-type protein kinase.				response to toxin	integral to membrane	ATP binding|calcium channel activity|metal ion binding|protein binding|protein serine/threonine kinase activity			NS(2)|breast(1)|central_nervous_system(1)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(22)|liver(1)|lung(53)|ovary(1)|prostate(7)|skin(12)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(1)	126						GCACAGTGCTCTCCTGGAAGA	0.473000													17	171					5.3912e-06	6.8309e-06	0.006122	1	0
UBR2	23304	broad.mit.edu	37	6	42600601	42600601	+	Nonsense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:42600601G>T	ENST00000372901.1	+	13	1762	c.1504G>T	c.(1504-1506)Gaa>Taa	p.E502*	UBR2_ENST00000372883.3_5'UTR|UBR2_ENST00000372899.1_Nonsense_Mutation_p.E502*			Q8IWV8	UBR2_HUMAN	ubiquitin protein ligase E3 component n-recognin 2	502					cellular response to leucine|chromatin silencing|histone H2A ubiquitination|negative regulation of TOR signaling cascade	nucleus|plasma membrane	leucine binding|zinc ion binding			breast(1)|central_nervous_system(1)|endometrium(10)|kidney(7)|large_intestine(14)|lung(22)|ovary(3)|pancreas(1)|skin(5)	64	Colorectal(47;0.196)		Colorectal(64;0.00062)|COAD - Colon adenocarcinoma(64;0.00152)|all cancers(41;0.004)|KIRC - Kidney renal clear cell carcinoma(15;0.02)|Kidney(15;0.0388)|OV - Ovarian serous cystadenocarcinoma(102;0.196)			GAAGTTCCTAGAAGGGTTTGA	0.323000													5	44					0.000602214	0.000692236	0.014758	1	0
OR2C3	81472	broad.mit.edu	37	1	247695110	247695110	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:247695110C>A	ENST00000366487.3	-	2	1065	c.704G>T	c.(703-705)cGg>cTg	p.R235L	GCSAML_ENST00000366489.1_Intron|GCSAML_ENST00000463359.1_Intron|GCSAML_ENST00000366490.3_Intron|GCSAML_ENST00000527541.1_Intron|GCSAML_ENST00000531662.1_Intron|GCSAML_ENST00000366491.2_Intron|GCSAML_ENST00000527084.1_Intron	NM_198074.4	NP_932340.3	Q8N628	OR2C3_HUMAN	olfactory receptor, family 2, subfamily C, member 3	235					sensory perception of smell	integral to membrane|plasma membrane	olfactory receptor activity			breast(1)|endometrium(5)|large_intestine(2)|lung(31)|ovary(1)|prostate(1)|skin(2)	43	all_cancers(71;4.51e-05)|all_epithelial(71;1.3e-05)|Breast(184;0.0149)|Ovarian(71;0.0377)|all_lung(81;0.0662)|Lung NSC(105;0.0724)	all_cancers(173;0.0242)	OV - Ovarian serous cystadenocarcinoma(106;0.0241)			TGCCTTTCTCCGCCCTTCTGC	0.557000													11	82					0.010729	0.0115028	0.010729	1	0
RHBG	57127	broad.mit.edu	37	1	156347138	156347138	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:156347138C>T	ENST00000400992.2	+	3	395	c.27C>T	c.(25-27)ctC>ctT	p.L9L	RHBG_ENST00000368246.2_Silent_p.L78L|RHBG_ENST00000368249.1_Silent_p.L78L|RHBG_ENST00000537040.1_Intron|RHBG_ENST00000451864.2_Silent_p.L9L|RHBG_ENST00000255013.3_Silent_p.L9L			Q9H310	RHBG_HUMAN	Rh family, B glycoprotein (gene/pseudogene)	78					transepithelial ammonium transport	anchored to plasma membrane|basolateral plasma membrane|cytoplasmic vesicle membrane|integral to plasma membrane|spectrin-associated cytoskeleton	ammonia transmembrane transporter activity|ammonium transmembrane transporter activity|ankyrin binding			endometrium(1)|kidney(1)|large_intestine(4)|lung(9)|ovary(3)|skin(2)|stomach(1)|urinary_tract(1)	22	Hepatocellular(266;0.158)					TTGGCTTCCTCATGGTCTTCC	0.637000													10	118					0	0	0.004990	0	0
DAXX	1616	broad.mit.edu	37	6	33289692	33289692	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:33289692G>A	ENST00000374542.5	-	2	215	c.11C>T	c.(10-12)gCt>gTt	p.A4V	DAXX_ENST00000414083.2_Intron|DAXX_ENST00000266000.6_Missense_Mutation_p.A4V	NM_001141969.1|NM_001141970.1|NM_001350.4	NP_001135441.1|NP_001135442.1|NP_001341.1	Q9UER7	DAXX_HUMAN	death-domain associated protein	4	Necessary for interaction with USP7.				activation of JUN kinase activity|androgen receptor signaling pathway|apoptosis|induction of apoptosis via death domain receptors|interspecies interaction between organisms|negative regulation of transcription, DNA-dependent|regulation of protein ubiquitination|transcription, DNA-dependent	chromosome, centromeric region|cytosol|nucleolus|PML body	androgen receptor binding|heat shock protein binding|p53 binding|protein homodimerization activity|protein N-terminus binding|receptor signaling protein activity|transcription factor binding|ubiquitin protein ligase binding			breast(1)|central_nervous_system(2)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(5)|large_intestine(2)|lung(7)|ovary(3)|pancreas(18)|prostate(3)|skin(4)|upper_aerodigestive_tract(4)|urinary_tract(1)	55						GATGCTGTTAGCGGTGGCCAT	0.602000			"""Mis, F, N"""		Pancreatic neuroendocrine tumors. Paediatric GBM								12	48					0	0	0.003163	0	0
SYMPK	8189	broad.mit.edu	37	19	46351054	46351054	+	Missense_Mutation	SNP	A	A	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:46351054A>C	ENST00000245934.7	-	7	876	c.632T>G	c.(631-633)aTc>aGc	p.I211S		NM_004819.2	NP_004810.2	Q92797	SYMPK_HUMAN	symplekin	211					cell adhesion|mRNA processing	cytoplasm|cytoskeleton|nucleoplasm|tight junction	protein binding			breast(3)|central_nervous_system(1)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(7)|liver(1)|lung(25)|ovary(1)|urinary_tract(1)	45		all_neural(266;0.0299)|Ovarian(192;0.0308)		OV - Ovarian serous cystadenocarcinoma(262;0.00509)|GBM - Glioblastoma multiforme(486;0.0593)		GTCCAGGCTGATATCATGCTC	0.597000													6	31					0	0	0.001168	0	0
CAMK4	814	broad.mit.edu	37	5	110710570	110710570	+	Missense_Mutation	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:110710570C>T	ENST00000282356.4	+	3	661	c.263C>T	c.(262-264)aCt>aTt	p.T88I	CAMK4_ENST00000512453.1_Missense_Mutation_p.T88I	NM_001744.4	NP_001735.1	Q16566	KCC4_HUMAN	calcium/calmodulin-dependent protein kinase IV	88	Protein kinase.				activation of phospholipase C activity|nerve growth factor receptor signaling pathway|synaptic transmission	cytosol|nucleoplasm	ATP binding|calmodulin binding|calmodulin-dependent protein kinase activity			endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(13)|ovary(3)|prostate(2)|skin(1)|urinary_tract(1)	30		all_cancers(142;1.49e-05)|all_epithelial(76;1.82e-07)|Prostate(80;0.00964)|all_lung(232;0.0181)|Lung NSC(167;0.0298)|Ovarian(225;0.0446)|Colorectal(57;0.0478)|Breast(839;0.244)		OV - Ovarian serous cystadenocarcinoma(64;3.79e-08)|Epithelial(69;5.29e-08)|all cancers(49;1.1e-05)|COAD - Colon adenocarcinoma(37;0.109)		ATCGTAAGAACTGAGATAGGA	0.373000													7	71					0	0	0.001984	0	0
XIRP2	129446	broad.mit.edu	37	2	168105791	168105791	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:168105791C>G	ENST00000409195.1	+	9	7978	c.7889C>G	c.(7888-7890)tCc>tGc	p.S2630C	XIRP2_ENST00000409273.1_Missense_Mutation_p.S2408C|XIRP2_ENST00000409043.1_Intron|XIRP2_ENST00000420519.1_Intron|XIRP2_ENST00000409756.2_Intron|XIRP2_ENST00000409605.1_Intron|XIRP2_ENST00000409728.1_Intron|XIRP2_ENST00000295237.9_Missense_Mutation_p.S2630C	NM_152381.5	NP_689594.4	A4UGR9	XIRP2_HUMAN	xin actin-binding repeat containing 2	2455					actin cytoskeleton organization	cell junction	actin binding			NS(3)|biliary_tract(2)|breast(5)|cervix(3)|endometrium(16)|haematopoietic_and_lymphoid_tissue(2)|kidney(18)|large_intestine(51)|lung(160)|ovary(7)|pancreas(3)|prostate(11)|skin(14)|stomach(5)|upper_aerodigestive_tract(8)|urinary_tract(7)	315						AACCAACTCTCCACAACATCG	0.448000													12	148					0	0	0.013537	0	0
KCNG1	3755	broad.mit.edu	37	20	49620825	49620825	+	Silent	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:49620825G>T	ENST00000371571.4	-	3	1578	c.1293C>A	c.(1291-1293)gtC>gtA	p.V431V	RP5-955M13.4_ENST00000424566.1_RNA|RP5-955M13.3_ENST00000506387.1_RNA	NM_002237.3	NP_002228.2	Q9UIX4	KCNG1_HUMAN	potassium voltage-gated channel, subfamily G, member 1	431						voltage-gated potassium channel complex	voltage-gated potassium channel activity			breast(1)|central_nervous_system(2)|cervix(1)|endometrium(4)|kidney(1)|large_intestine(7)|liver(1)|lung(11)|ovary(2)|prostate(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	35						TGCTCCTGGGGACCATGTCGC	0.632000													6	77					3.59834e-05	4.36103e-05	0.001168	1	0
WDR96	80217	broad.mit.edu	37	10	105920842	105920842	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:105920842C>G	ENST00000357060.3	-	27	3608	c.3493G>C	c.(3493-3495)Gag>Cag	p.E1165Q	WDR96_ENST00000428666.1_Missense_Mutation_p.E1166Q	NM_025145.5	NP_079421.5	Q8NDM7	WDR96_HUMAN	WD repeat domain 96	1165										NS(1)|breast(3)|cervix(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|kidney(7)|large_intestine(14)|lung(21)|ovary(4)|prostate(2)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(3)	72						ACTTTTTTCTCATAATCTTTG	0.333000													6	105					0	0	0.001168	0	0
SERPINA3	12	broad.mit.edu	37	14	95085719	95085719	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:95085719C>T	ENST00000553947.1	+	6	1794	c.906C>T	c.(904-906)atC>atT	p.I302I	SERPINA3_ENST00000482740.1_Silent_p.I59I|SERPINA3_ENST00000467132.1_Silent_p.I277I|SERPINA3_ENST00000556388.1_Intron|SERPINA3_ENST00000393078.3_Silent_p.I277I|SERPINA3_ENST00000393080.4_Silent_p.I277I			P01011	AACT_HUMAN	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	277					acute-phase response|maintenance of gastrointestinal epithelium|regulation of lipid metabolic process|regulation of proteolysis	extracellular region|nucleus	DNA binding|protein binding|serine-type endopeptidase inhibitor activity			NS(1)|central_nervous_system(2)|endometrium(4)|kidney(3)|large_intestine(6)|lung(17)|ovary(2)|pancreas(1)|skin(3)|stomach(1)	40		all_cancers(154;0.0525)|all_epithelial(191;0.179)		COAD - Colon adenocarcinoma(157;0.212)|Epithelial(152;0.228)		CACTCTTCATCCTCCCTGATC	0.547000													5	14					0	0	0.001168	0	0
TLN2	83660	broad.mit.edu	37	15	62950011	62950011	+	Silent	SNP	C	C	T	rs148402491		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:62950011C>T	ENST00000561311.1	+	8	932	c.702C>T	c.(700-702)ttC>ttT	p.F234F	TLN2_ENST00000306829.6_Silent_p.F234F			Q9Y4G6	TLN2_HUMAN	talin 2	234	FERM.				cell adhesion|cell-cell junction assembly|cytoskeletal anchoring at plasma membrane	actin cytoskeleton|cytoplasm|focal adhesion|ruffle|synapse	actin binding|insulin receptor binding|structural constituent of cytoskeleton			NS(3)|breast(6)|central_nervous_system(3)|endometrium(8)|kidney(8)|large_intestine(20)|lung(34)|ovary(6)|prostate(1)|skin(4)|stomach(1)|upper_aerodigestive_tract(5)	99						CTGTCTCCTTCGAGAAAGCTT	0.453000													5	162					0	0	0.014758	0	0
F5	2153	broad.mit.edu	37	1	169526046	169526046	+	Missense_Mutation	SNP	G	G	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:169526046G>T	ENST00000367796.3	-	6	991	c.790C>A	c.(790-792)Cca>Aca	p.P264T	F5_ENST00000546081.1_Missense_Mutation_p.P127T|F5_ENST00000367797.3_Missense_Mutation_p.P264T			P12259	FA5_HUMAN	coagulation factor V (proaccelerin, labile factor)	264	F5/8 type A 1.|Plastocyanin-like 2.				cell adhesion|platelet activation|platelet degranulation	plasma membrane|platelet alpha granule lumen	copper ion binding|oxidoreductase activity	p.P264T(1)		NS(1)|breast(4)|central_nervous_system(4)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(10)|large_intestine(24)|lung(55)|ovary(3)|prostate(4)|skin(5)|stomach(1)|upper_aerodigestive_tract(7)|urinary_tract(1)	128	all_hematologic(923;0.208)				Drotrecogin alfa(DB00055)	AATAATTCTGGCCCCGAGCTC	0.493000													16	35					3.52763e-06	4.54718e-06	0.004990	1	0
MYH3	4621	broad.mit.edu	37	17	10533201	10533201	+	Silent	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:10533201C>A	ENST00000583535.1	-	39	5703	c.5616G>T	c.(5614-5616)ctG>ctT	p.L1872L	MYH3_ENST00000226209.7_Silent_p.L1872L	NM_002470.3	NP_002461.2	P11055	MYH3_HUMAN	myosin, heavy chain 3, skeletal muscle, embryonic	1872					muscle filament sliding|muscle organ development	cytosol|myofibril|myosin filament	actin binding|ATP binding|calmodulin binding|microfilament motor activity			breast(2)|central_nervous_system(2)|cervix(1)|endometrium(8)|kidney(5)|large_intestine(18)|lung(30)|ovary(4)|pancreas(1)|prostate(4)|skin(2)|upper_aerodigestive_tract(5)|urinary_tract(1)	83						CTTTCACTTGCAGTTTATCCA	0.517000													6	165					0.0135373	0.0144441	0.013537	1	0
ZNF318	24149	broad.mit.edu	37	6	43323078	43323078	+	Nonsense_Mutation	SNP	G	G	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:43323078G>C	ENST00000361428.2	-	4	2071	c.1994C>G	c.(1993-1995)tCa>tGa	p.S665*	ZNF318_ENST00000318149.3_Nonsense_Mutation_p.S665*	NM_014345.2	NP_055160.2	Q5VUA4	ZN318_HUMAN	zinc finger protein 318	665					meiosis|regulation of transcription, DNA-dependent|transcription, DNA-dependent	cytoplasm|nucleus	nucleic acid binding|zinc ion binding			autonomic_ganglia(1)|breast(8)|central_nervous_system(1)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(11)|lung(21)|ovary(3)|prostate(1)|skin(1)|stomach(1)|urinary_tract(1)	61			Colorectal(64;0.00245)|COAD - Colon adenocarcinoma(64;0.00536)|all cancers(41;0.0171)|OV - Ovarian serous cystadenocarcinoma(102;0.0579)			TCGATCAGCTGAGAAGCAGTG	0.547000													7	116					0	0	0.004482	0	0
ZFHX4	79776	broad.mit.edu	37	8	77766701	77766701	+	Missense_Mutation	SNP	A	A	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:77766701A>G	ENST00000521891.2	+	10	7992	c.7544A>G	c.(7543-7545)cAc>cGc	p.H2515R	ZFHX4_ENST00000455469.2_Missense_Mutation_p.H2470R|ZFHX4_ENST00000518282.1_Missense_Mutation_p.H2489R|ZFHX4_ENST00000050961.6_Missense_Mutation_p.H2470R	NM_024721.4	NP_078997.4	Q86UP3	ZFHX4_HUMAN	zinc finger homeobox 4	2470						nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			NS(3)|breast(11)|central_nervous_system(1)|endometrium(36)|haematopoietic_and_lymphoid_tissue(2)|kidney(15)|large_intestine(66)|liver(2)|lung(245)|ovary(11)|pancreas(3)|prostate(11)|skin(7)|upper_aerodigestive_tract(13)|urinary_tract(6)	432			BRCA - Breast invasive adenocarcinoma(89;0.0895)			CAGCACATGCACTTCCTTGCT	0.483000										HNSCC(33;0.089)			17	215					0	0	0.006122	0	0
PDE4B	5142	broad.mit.edu	37	1	66713200	66713200	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:66713200C>G	ENST00000423207.2	+	2	779	c.294C>G	c.(292-294)agC>agG	p.S98R	PDE4B_ENST00000371049.3_Missense_Mutation_p.S113R|PDE4B_ENST00000329654.4_Missense_Mutation_p.S113R	NM_001037340.1	NP_001032417.1	Q07343	PDE4B_HUMAN	phosphodiesterase 4B, cAMP-specific	113					signal transduction	cytosol|insoluble fraction|soluble fraction	3',5'-cyclic-AMP phosphodiesterase activity|metal ion binding			breast(1)|central_nervous_system(2)|cervix(1)|endometrium(2)|kidney(1)|large_intestine(6)|lung(14)|ovary(2)|prostate(2)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)	37					Adenosine monophosphate(DB00131)|Amrinone(DB01427)|Caffeine(DB00201)|Cilostazol(DB01166)|Dyphylline(DB00651)|Enprofylline(DB00824)|Papaverine(DB01113)|Pentoxifylline(DB00806)|Theophylline(DB00277)	CCCAGGCCAGCTCTTCCGCTG	0.532000													22	280					0	0	0.014323	0	0
NSUN2	54888	broad.mit.edu	37	5	6611068	6611068	+	Splice_Site	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:6611068C>T	ENST00000264670.6	-	11	1537	c.1226_splice	c.e11+1	p.C409_splice	NSUN2_ENST00000539938.1_Splice_Site_p.C173_splice|NSUN2_ENST00000506139.1_Splice_Site_p.C374_splice	NM_017755.5	NP_060225.4	Q08J23	NSUN2_HUMAN	NOP2/Sun RNA methyltransferase family, member 2	409						cytoplasm|nucleolus	tRNA (cytosine-5-)-methyltransferase activity|tRNA binding			breast(1)|endometrium(6)|kidney(2)|large_intestine(5)|lung(23)|ovary(1)|prostate(2)|upper_aerodigestive_tract(1)	41						ACCAGCTCACCATCGCTCCAG	0.617000													3	29					0	0	0.004672	0	0
TMEM126A	84233	broad.mit.edu	37	11	85367357	85367357	+	Missense_Mutation	SNP	C	C	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:85367357C>G	ENST00000304511.2	+	5	509	c.400C>G	c.(400-402)Caa>Gaa	p.Q134E	TMEM126A_ENST00000528105.1_Missense_Mutation_p.Q64E|TMEM126A_ENST00000532180.1_Missense_Mutation_p.Q64E	NM_032273.3	NP_115649.1	Q9H061	T126A_HUMAN	transmembrane protein 126A	134						integral to membrane|mitochondrion				breast(1)|endometrium(1)|large_intestine(1)|lung(1)|ovary(2)|stomach(1)	7		Acute lymphoblastic leukemia(157;4.88e-06)|all_hematologic(158;0.00572)				TTACAGGTATCAATCAGCTCT	0.348000													8	46					0	0	0.006214	0	0
TNFAIP8	25816	broad.mit.edu	37	5	118728517	118728517	+	Missense_Mutation	SNP	C	C	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:118728517C>A	ENST00000504771.2	+	2	1815	c.38C>A	c.(37-39)aCa>aAa	p.T13K	TNFAIP8_ENST00000513374.1_Missense_Mutation_p.T25K|TNFAIP8_ENST00000274456.6_Missense_Mutation_p.T3K|TNFAIP8_ENST00000503646.1_Missense_Mutation_p.T13K|TNFAIP8_ENST00000415806.2_3'UTR|TNFAIP8_ENST00000504642.1_Missense_Mutation_p.T15K	NM_014350.2	NP_055165.2	O95379	TFIP8_HUMAN	tumor necrosis factor, alpha-induced protein 8	13					anti-apoptosis|apoptosis|negative regulation of anti-apoptosis	cytoplasm	caspase inhibitor activity|protein binding			ovary(1)	1		all_cancers(142;0.0317)|Prostate(80;0.111)|Breast(839;0.231)		Epithelial(69;4.63e-83)|OV - Ovarian serous cystadenocarcinoma(64;1.39e-82)|all cancers(49;4.88e-75)|GBM - Glioblastoma multiforme(465;0.00338)|BRCA - Breast invasive adenocarcinoma(61;0.0148)|COAD - Colon adenocarcinoma(49;0.0829)		TTAGTGGCCACAGATGTCTTT	0.373000													3	2					0.00909568	0.00979873	0.009096	1	0
SCN8A	6334	broad.mit.edu	37	12	52163071	52163071	+	Silent	SNP	C	C	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:52163071C>T	ENST00000354534.5	+	17	3502	c.3324C>T	c.(3322-3324)ctC>ctT	p.L1108L	SCN8A_ENST00000545061.1_Silent_p.L1108L	NM_001177984.2|NM_014191.3	NP_001171455.1|NP_055006.1	Q9UQD0	SCN8A_HUMAN	sodium channel, voltage gated, type VIII, alpha subunit	1108					axon guidance|myelination|peripheral nervous system development	cytoplasmic membrane-bounded vesicle|node of Ranvier	ATP binding|voltage-gated sodium channel activity			breast(2)|central_nervous_system(1)|cervix(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(7)|lung(19)|ovary(8)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(2)	55				BRCA - Breast invasive adenocarcinoma(357;0.181)	Lamotrigine(DB00555)	TTGAGAACCTCAACACAGAGG	0.498000													4	38					0	0	0.009096	0	0
TCF7L2	6934	broad.mit.edu	37	10	114925376	114925376	+	Nonsense_Mutation	SNP	C	C	G	rs61724286		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:114925376C>G	ENST00000355995.4	+	15	2012	c.1505C>G	c.(1504-1506)tCa>tGa	p.S502*	TCF7L2_ENST00000369386.1_3'UTR|TCF7L2_ENST00000536810.1_Nonsense_Mutation_p.S485*|TCF7L2_ENST00000543371.1_Nonsense_Mutation_p.S485*|TCF7L2_ENST00000542695.1_Nonsense_Mutation_p.S218*|TCF7L2_ENST00000466338.1_3'UTR|TCF7L2_ENST00000538897.1_Missense_Mutation_p.Q478E|TCF7L2_ENST00000369389.1_Missense_Mutation_p.Q172E|TCF7L2_ENST00000355717.4_Missense_Mutation_p.Q485E|TCF7L2_ENST00000369397.4_Nonsense_Mutation_p.S479*|TCF7L2_ENST00000545257.1_Nonsense_Mutation_p.S502*			Q9NQB0	TF7L2_HUMAN	transcription factor 7-like 2 (T-cell specific, HMG-box)	502	Promoter-specific activation domain.				anti-apoptosis|blood vessel development|canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition|cell cycle arrest|cell proliferation|fat cell differentiation|glucose homeostasis|maintenance of DNA repeat elements|myoblast cell fate commitment|negative regulation of canonical Wnt receptor signaling pathway|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|pancreas development|positive regulation of heparan sulfate proteoglycan biosynthetic process|positive regulation of insulin secretion|positive regulation of protein binding|positive regulation of protein export from nucleus|positive regulation of protein kinase B signaling cascade|positive regulation of transcription from RNA polymerase II promoter|regulation of hormone metabolic process|regulation of smooth muscle cell proliferation|response to glucose stimulus	beta-catenin-TCF7L2 complex|PML body|protein-DNA complex	armadillo repeat domain binding|beta-catenin binding|gamma-catenin binding|nuclear hormone receptor binding|protein kinase binding|sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity|transcription factor binding|transcription regulatory region DNA binding		VTI1A/TCF7L2(8)	central_nervous_system(1)|endometrium(3)|kidney(1)|large_intestine(24)|liver(2)|lung(8)|ovary(1)|skin(1)	41		Breast(234;0.058)|Colorectal(252;0.0615)		Epithelial(162;0.00554)|all cancers(201;0.02)		CCACCCTCTTCAGATGGAAGC	0.557000			T	VTI1A	colorectal								14	117					0	0	0.004990	0	0
ADAMTS3	9508	broad.mit.edu	37	4	73178124	73178124	+	Missense_Mutation	SNP	G	G	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:73178124G>A	ENST00000286657.4	-	13	1841	c.1805C>T	c.(1804-1806)aCa>aTa	p.T602I		NM_014243.2	NP_055058.2	O15072	ATS3_HUMAN	ADAM metallopeptidase with thrombospondin type 1 motif, 3	602	TSP type-1 1.				collagen catabolic process|collagen fibril organization|proteolysis	proteinaceous extracellular matrix	heparin binding|metalloendopeptidase activity|zinc ion binding			NS(1)|breast(2)|cervix(1)|endometrium(5)|kidney(6)|large_intestine(21)|lung(33)|ovary(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	76			Epithelial(6;4.97e-05)|OV - Ovarian serous cystadenocarcinoma(6;5.66e-05)|all cancers(17;0.000486)|Lung(101;0.103)|LUSC - Lung squamous cell carcinoma(112;0.154)			GCATTCTTCTGTGTTACAAAG	0.433000													7	55					0	0	0.001984	0	0
LINC01389	102724077	broad.mit.edu	37	1	47848450	47848453	+	RNA	DEL	TTTC	TTTC	-	rs60232789		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:47848450_47848453delTTTC	ENST00000420876.1	-	0	267																											tttcttttcttttctttttttttt	0.363													2	4	---	---	---	---					
RP11-466L17.1	0	broad.mit.edu	37	1	56050062	56050063	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:56050062_56050063insC	ENST00000422374.1	+	0	158																											ATGAATGACGGCCCCTGAAAGT	0.495													2	4	---	---	---	---					
GNG12-AS1	100289178	broad.mit.edu	37	1	68410018	68410018	+	RNA	DEL	A	A	-	rs35608379		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:68410018delA	ENST00000420587.1	+	0	134				GNG12-AS1_ENST00000413628.1_RNA	NR_040077.1		Q6ZVV5	Q6ZVV5_HUMAN																			gctaaaatacaaaaaaaaaat	0.522													2	4	---	---	---	---					
RP5-965F6.2	0	broad.mit.edu	37	1	112800581	112800581	+	RNA	DEL	A	A	-	rs36056640		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:112800581delA	ENST00000427290.1	-	0	167																											gctccatctcaaaaaaaaaaa	0.502													2	4	---	---	---	---					
SLC16A1-AS1	100506392	broad.mit.edu	37	1	113513439	113513440	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:113513439_113513440insC	ENST00000435800.2	+	0	627																											CTACCCCATTTCCCCCTGCACA	0.446													2	4	---	---	---	---					
LOC101928995	101928995	broad.mit.edu	37	1	116462257	116462258	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:116462257_116462258insG	ENST00000438885.1	+	0	184																											gagggaaatttggggggcagct	0.505													2	4	---	---	---	---					
AL592494.5	0	broad.mit.edu	37	1	121168622	121168623	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:121168622_121168623insA	ENST00000417218.1	+	0	551				RP11-343N15.2_ENST00000445260.2_lincRNA																							caggctctaccaaaaaaaaaaa	0.480													3	3	---	---	---	---					
LOC101927209	101927209	broad.mit.edu	37	1	142623788	142623788	+	RNA	DEL	T	T	-	rs149122083		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:142623788delT	ENST00000369381.2	-	0	5218				RP11-417J8.3_ENST00000426408.1_lincRNA																							TGGGTTCTGGTTTTAGCACGT	0.438													9	5	---	---	---	---					
LOC101927209	101927209	broad.mit.edu	37	1	142642817	142642818	+	RNA	INS	-	-	T	rs71249303		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:142642817_142642818insT	ENST00000369381.2	-	0	2507				RP11-417J8.3_ENST00000426408.1_lincRNA																							GTTTTCTTGGGTTTTTTTTTTT	0.342													5	8	---	---	---	---					
RP11-782C8.2	0	broad.mit.edu	37	1	143161966	143161966	+	RNA	DEL	G	G	-	rs61786873	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:143161966delG	ENST00000412204.2	-	0	2503				RP11-782C8.1_ENST00000438000.1_lincRNA|RP11-782C8.4_ENST00000424474.2_lincRNA																							aggaAGAGACgggagaaaagt	0.388													4	9	---	---	---	---					
LOC101928979	101928979	broad.mit.edu	37	1	145381924	145381925	+	RNA	INS	-	-	AAAAAAAA	rs34675346		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:145381924_145381925insAAAAAAAA	ENST00000419817.1	-	0	307																											gactccgtctcaaaaaaaaaaa	0.490													2	4	---	---	---	---					
FMO9P	116123	broad.mit.edu	37	1	166583114	166583114	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:166583114delG	ENST00000477875.1	+	0	552					NR_002925.2																						ttaaataagtggtcatgaaaa	0.318													2	4	---	---	---	---					
RP1-15D23.2	0	broad.mit.edu	37	1	172793201	172793201	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:172793201delG	ENST00000432694.1	+	0	223																											ccatgtctgtgagttgggttc	0.413													4	2	---	---	---	---					
LOC102724601	102724601	broad.mit.edu	37	1	174104835	174104835	+	RNA	DEL	T	T	-	rs75165126		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:174104835delT	ENST00000426899.1	-	0	338																											aagttgctcctcctaaaattt	0.388													4	2	---	---	---	---					
LOC730102	730102	broad.mit.edu	37	1	178004395	178004396	+	RNA	INS	-	-	T	rs71949629		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:178004395_178004396insT	ENST00000476232.1	-	0	162																											CTTACTGAGGAttttttttttt	0.470													3	4	---	---	---	---					
LINC01031	101929184	broad.mit.edu	37	1	193296672	193296672	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:193296672delC	ENST00000420807.1	+	0	194																											tatttccctaccccactcccc	0.363													2	4	---	---	---	---					
LINC01031	101929184	broad.mit.edu	37	1	193300055	193300056	+	RNA	INS	-	-	A	rs58921440	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:193300055_193300056insA	ENST00000420807.1	+	0	194																											ttttcaaaaaccagtacttcat	0.292													6	5	---	---	---	---					
CTD-2090I13.1	0	broad.mit.edu	37	1	227589267	227589268	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:227589267_227589268insG	ENST00000445817.1	+	0	210																											tggccagaggcggggggaaaac	0.579													3	5	---	---	---	---					
RP11-518L10.5	0	broad.mit.edu	37	1	244570145	244570145	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr1:244570145delA	ENST00000417765.1	-	0	157																											ctactgaaggaaataaagaca	0.378													2	4	---	---	---	---					
LOC100506457	100506457	broad.mit.edu	37	2	12281761	12281762	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:12281761_12281762insC	ENST00000412294.1	+	0	197																											ACAAAATGCAGCCCCCCCATAA	0.431													3	4	---	---	---	---					
LINC00276	100499171	broad.mit.edu	37	2	14525600	14525605	+	RNA	DEL	ACACAC	ACACAC	-	rs72278719		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:14525600_14525605delACACAC	ENST00000418420.1	-	0	116					NR_103814.1																						acatacacatacacacacacacacac	0.398													3	3	---	---	---	---					
AC010880.1	0	broad.mit.edu	37	2	16564202	16564202	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:16564202delT	ENST00000427950.1	+	0	83																											agtttgtgtcttttttttttc	0.284													2	4	---	---	---	---					
AC012593.1	0	broad.mit.edu	37	2	35258363	35258364	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:35258363_35258364insT	ENST00000588944.1	+	0	115																											tttcctgtgccttttggttgta	0.450													3	5	---	---	---	---					
SLC8A1-AS1	100128590	broad.mit.edu	37	2	40283342	40283343	+	RNA	INS	-	-	G	rs139627901	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:40283342_40283343insG	ENST00000439606.1	+	0	249				SLC8A1-AS1_ENST00000418854.1_RNA|SLC8A1-AS1_ENST00000599740.1_RNA																							aatgacttgccggggggaataa	0.386													2	4	---	---	---	---					
AC007317.1	0	broad.mit.edu	37	2	40987092	40987093	+	RNA	DEL	AA	AA	-	rs57636926	byFrequency	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:40987092_40987093delAA	ENST00000420187.1	+	0	312																											acacacacacaaacacacacac	0.351													2	4	---	---	---	---					
RP11-444A22.1	0	broad.mit.edu	37	2	59656177	59656177	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:59656177delC	ENST00000606382.1	-	0	433																											CTGTTAATGGCCCCAGGGACC	0.393													2	4	---	---	---	---					
RP11-444A22.1	0	broad.mit.edu	37	2	60196405	60196414	+	RNA	DEL	TCCTACTCTA	TCCTACTCTA	-	rs70957447		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:60196405_60196414delTCCTACTCTA	ENST00000606382.1	-	0	110																											AATGTGTTTCTCCTACTCTATCTTTTATTC	0.433													3	4	---	---	---	---					
RP11-444A22.1	0	broad.mit.edu	37	2	60283597	60283598	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:60283597_60283598insG	ENST00000606382.1	-	0	110																											caaggtcccacggggggttgaa	0.460													2	4	---	---	---	---					
ANKRD36BP2	645784	broad.mit.edu	37	2	89075573	89075582	+	RNA	DEL	GGTCCTATTT	GGTCCTATTT	-	rs5832741		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:89075573_89075582delGGTCCTATTT	ENST00000393525.3	+	0	401																											ATCCTTCTGGGGTCCTATTTGGTCCTTTCG	0.386													4	4	---	---	---	---					
SULT1C2P1	151234	broad.mit.edu	37	2	108955195	108955195	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:108955195delA	ENST00000427208.1	+	0	445					NR_037191.1																						taaaaTAAAGAAAAAAAAGAA	0.308													2	4	---	---	---	---					
LOC100506797	100506797	broad.mit.edu	37	2	118907891	118907892	+	RNA	INS	-	-	T	rs140754322	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:118907891_118907892insT	ENST00000414886.1	-	0	533																											ACTTGATTTAATTTTTTTTCAA	0.396													2	4	---	---	---	---					
PTPN18	26469	broad.mit.edu	37	2	131129929	131129934	+	In_Frame_Del	DEL	GACGGG	GACGGG	-	rs112040677		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:131129929_131129934delGACGGG	ENST00000175756.5	+	13	1214_1219	c.1113_1118delGACGGG	c.(1111-1119)cag>ca	p.QTG371del	PTPN18_ENST00000347849.3_In_Frame_Del_p.QTG264del	NM_014369.3	NP_055184.2	Q99952	PTN18_HUMAN	protein tyrosine phosphatase, non-receptor type 18 (brain-derived)	371						cytoplasm|nucleus	non-membrane spanning protein tyrosine phosphatase activity	p.T378_G379delTG(1)		endometrium(1)|kidney(3)|large_intestine(2)|lung(5)|ovary(3)|prostate(1)	15	Colorectal(110;0.1)					gtgggacgcagacggggacggggacg	0.777													5	1	---	---	---	---					
AC023469.2	0	broad.mit.edu	37	2	151843065	151843066	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:151843065_151843066insC	ENST00000425983.1	+	0	10																											gctgctccctgcccccacccca	0.540													2	4	---	---	---	---					
AC018731.3	0	broad.mit.edu	37	2	152020960	152020960	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:152020960delA	ENST00000447078.1	-	0	90																											tacagcttataagcacttggc	0.428													2	4	---	---	---	---					
AC009478.1	0	broad.mit.edu	37	2	181504572	181504573	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:181504572_181504573insA	ENST00000429816.1	-	0	225																											aggaatacaacaaaaaacatca	0.297													2	4	---	---	---	---					
SSFA2	6744	broad.mit.edu	37	2	182756993	182756994	+	Frame_Shift_Ins	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:182756993_182756994insG	ENST00000431877.2	+	1	379_380	c.200_201insG	c.(199-201)gggfs	p.G67fs	SSFA2_ENST00000428267.2_5'UTR|SSFA2_ENST00000320370.7_Frame_Shift_Ins_p.G67fs|SSFA2_ENST00000409001.1_Frame_Shift_Ins_p.G67fs	NM_001130445.1	NP_001123917.1	P28290	SSFA2_HUMAN	sperm specific antigen 2	67						cytoplasm|plasma membrane	actin binding			breast(2)|central_nervous_system(1)|endometrium(3)|kidney(5)|large_intestine(5)|lung(18)|prostate(1)|skin(1)|upper_aerodigestive_tract(2)	38			OV - Ovarian serous cystadenocarcinoma(117;0.0856)			CTGCCGGCAGCGGGGGGAAGAG	0.723													2	4	---	---	---	---					
LINC01473	101927217	broad.mit.edu	37	2	186936625	186936625	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:186936625delA	ENST00000456653.2	-	0	167																											ccaaaggcagaaaaaaaaaaa	0.413													2	4	---	---	---	---					
AC019330.1	0	broad.mit.edu	37	2	199594334	199594335	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:199594334_199594335insT	ENST00000440609.1	-	0	98																											gtttttctttctttttttctat	0.406													2	4	---	---	---	---					
AC018717.1	0	broad.mit.edu	37	2	199813621	199813621	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:199813621delA	ENST00000456031.1	-	0	114																											attagtccagaaacaaatgag	0.398													2	4	---	---	---	---					
AC007879.5	0	broad.mit.edu	37	2	208135352	208135352	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:208135352delC	ENST00000412387.1	-	0	315				AC007879.6_ENST00000438824.1_lincRNA																							ctgatattttcttatagcagc	0.423													2	4	---	---	---	---					
AC007563.5	0	broad.mit.edu	37	2	217589782	217589782	+	RNA	DEL	A	A	-	rs113192629		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:217589782delA	ENST00000447289.1	+	0	388																											tccatctcggaaaaaaaaaaa	0.502													2	4	---	---	---	---					
AC067956.1	0	broad.mit.edu	37	2	221496746	221496747	+	RNA	INS	-	-	T	rs138897046	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:221496746_221496747insT	ENST00000414512.1	+	0	550																											TAATTATGTGGTTTTTTTCTCT	0.272													2	4	---	---	---	---					
LINC01237	101927289	broad.mit.edu	37	2	242892262	242892263	+	RNA	DEL	TG	TG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr2:242892262_242892263delTG	ENST00000430555.1	+	0	329				AC131097.3_ENST00000457686.1_RNA|AC131097.3_ENST00000415434.1_RNA|AC131097.3_ENST00000439601.1_RNA|AC131097.3_ENST00000429947.1_RNA																							AGCGTGTCCCtgtgtgtgtgtg	0.574													2	4	---	---	---	---					
LINC01266	101927215	broad.mit.edu	37	3	781710	781710	+	RNA	DEL	T	T	-	rs35173635		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:781710delT	ENST00000420823.1	+	0	176																											tctctcttgctcgctcactca	0.323													6	5	---	---	---	---					
AC026188.1	0	broad.mit.edu	37	3	3472232	3472234	+	RNA	DEL	TTG	TTG	-	rs35588614		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:3472232_3472234delTTG	ENST00000455703.1	-	0	59																											tgttctgcaattgttgttggaaa	0.433													5	3	---	---	---	---					
LMCD1-AS1	100288428	broad.mit.edu	37	3	8403840	8403840	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:8403840delT	ENST00000420095.1	-	0	571				LMCD1-AS1_ENST00000452802.1_RNA|LMCD1-AS1_ENST00000446281.1_RNA	NR_033378.1																						TCAAATAGGATTTTTTTTTTT	0.398													3	3	---	---	---	---					
SATB1-AS1	101927777	broad.mit.edu	37	3	18934577	18934578	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:18934577_18934578insG	ENST00000425799.2	+	0	463																											ATAGTGAGGTTGGGGGGATTCC	0.366													2	4	---	---	---	---					
AC133680.1	0	broad.mit.edu	37	3	24904188	24904189	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:24904188_24904189insG	ENST00000455576.1	+	0	345																											aagtatccactgggggtcttgg	0.351													2	4	---	---	---	---					
ENTPD3-AS1	285266	broad.mit.edu	37	3	40426834	40426835	+	RNA	DEL	TG	TG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:40426834_40426835delTG	ENST00000439293.1	-	0	143																											tgtgtgtgtctgtgtgtgtgtg	0.406													3	5	---	---	---	---					
SUCLG2-AS1	101927111	broad.mit.edu	37	3	67796200	67796201	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:67796200_67796201insA	ENST00000482677.1	+	0	615																											GTGGTCACTACAAAAAAAAATG	0.361													2	4	---	---	---	---					
ZNF717	100131827	broad.mit.edu	37	3	75786761	75786761	+	Frame_Shift_Del	DEL	C	C	-	rs145576551		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:75786761delC	ENST00000478296.1	-	4	2139	c.1863delG	c.(1861-1863)ggfs	p.G621fs	ZNF717_ENST00000400845.3_Frame_Shift_Del_p.G664fs|ZNF717_ENST00000477374.1_Intron|ZNF717_ENST00000422325.1_Frame_Shift_Del_p.G671fs|ZNF717_ENST00000491507.1_Intron			C9JSV9	C9JSV9_HUMAN	zinc finger protein 717	671					regulation of transcription, DNA-dependent	intracellular	nucleic acid binding|zinc ion binding			autonomic_ganglia(6)|endometrium(3)|lung(2)|ovary(1)|stomach(7)	19						TACGGTTTTTCCCCGTGTGAG	0.408													2	4	---	---	---	---					
LINC00635	151658	broad.mit.edu	37	3	107565409	107565409	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:107565409delA	ENST00000464359.2	-	0	1105					NR_015414.1																						TTAGCATCGGAAAAGCCCCTT	0.483											OREG0015701	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	2	4	---	---	---	---					
LOC101927056	101927056	broad.mit.edu	37	3	125595457	125595458	+	RNA	INS	-	-	T	rs151323894	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:125595457_125595458insT	ENST00000468859.1	-	0	1456																											GACAGGGTTCCTCCCCTCAAAA	0.505													3	3	---	---	---	---					
PBX2P1	5088	broad.mit.edu	37	3	142895210	142895211	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:142895210_142895211insG	ENST00000560287.1	+	0	84_85																											AGGCGGGGCCCGGGGGGGGCCT	0.762													3	6	---	---	---	---					
RP11-23D24.2	0	broad.mit.edu	37	3	153295089	153295089	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:153295089delA	ENST00000493214.2	-	0	260																											GCCACAGCTTAAAAGATGAGT	0.388													2	4	---	---	---	---					
TMEM212-AS1	100874219	broad.mit.edu	37	3	171602533	171602533	+	RNA	DEL	T	T	-	rs35261388		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:171602533delT	ENST00000449106.1	-	0	382																											cttttttctcttttttttttt	0.408													3	5	---	---	---	---					
LINC00578	100505566	broad.mit.edu	37	3	177401030	177401030	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:177401030delT	ENST00000442937.1	+	0	428					NR_047568.1																						TTCTTATCACTTTGAACCAAC	0.378													2	4	---	---	---	---					
LOC100507391	100507391	broad.mit.edu	37	3	194495369	194495369	+	RNA	DEL	T	T	-	rs59165142		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:194495369delT	ENST00000423318.1	+	0	940					NR_037891.1																						ttttctttccttttttttttt	0.408													3	5	---	---	---	---					
SDHAP1	255812	broad.mit.edu	37	3	195713385	195713386	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr3:195713385_195713386insT	ENST00000427841.1	-	0	176					NR_003264.2																						AAAGCATGAACTTACGGAATCT	0.401													3	5	---	---	---	---					
ZNF718	255403	broad.mit.edu	37	4	129821	129821	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:129821delT	ENST00000510175.1	+	0	136							Q3SXZ3	ZN718_HUMAN	zinc finger protein 718						regulation of transcription, DNA-dependent|transcription, DNA-dependent	nucleus	DNA binding|zinc ion binding						all_cancers(4;0.0738)|all_epithelial(65;0.139)		Lung(54;0.0681)|Epithelial(2;0.0838)|all cancers(2;0.135)|LUSC - Lung squamous cell carcinoma(95;0.18)		GCTGATGAGATTACCTCTGCT	0.368													2	4	---	---	---	---					
CTBP1-AS2	92070	broad.mit.edu	37	4	1260132	1260133	+	RNA	DEL	AC	AC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:1260132_1260133delAC	ENST00000578730.1	+	0	2372																											aCACACCTATACACACACACAC	0.450													2	4	---	---	---	---					
LOC101929019	101929019	broad.mit.edu	37	4	12230160	12230161	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:12230160_12230161insA	ENST00000505386.1	+	0	147																											cttattctagcaacagaataca	0.381													2	4	---	---	---	---					
TAPT1-AS1	202020	broad.mit.edu	37	4	16254680	16254680	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:16254680delA	ENST00000570786.1	+	0	234				TAPT1-AS1_ENST00000573308.1_RNA|TAPT1-AS1_ENST00000573950.1_RNA	NR_027696.1																						caaatctgataaaaaaaaaat	0.423													2	4	---	---	---	---					
TAPT1-AS1	202020	broad.mit.edu	37	4	16256491	16256496	+	RNA	DEL	TTGTTG	TTGTTG	-	rs36206850		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:16256491_16256496delTTGTTG	ENST00000570786.1	+	0	234				TAPT1-AS1_ENST00000573308.1_RNA|TAPT1-AS1_ENST00000573950.1_RNA	NR_027696.1																						ACGAGGTTTTttgttgttgttgttgt	0.490													4	2	---	---	---	---					
SLC34A2	10568	broad.mit.edu	37	4	25671423	25671425	+	In_Frame_Del	DEL	CTG	CTG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:25671423_25671425delCTG	ENST00000382051.3	+	7	840_842	c.790_792delCTG	c.(790-792)del	p.L264del	SLC34A2_ENST00000504570.1_In_Frame_Del_p.L263del|SLC34A2_ENST00000503434.1_In_Frame_Del_p.L263del	NM_001177998.1|NM_006424.2	NP_001171469.1|NP_006415.2	O95436	NPT2B_HUMAN	solute carrier family 34 (type II sodium/phosphate contransporter), member 2	264					cellular phosphate ion homeostasis	apical plasma membrane|brush border membrane|integral to plasma membrane	phosphate binding|sodium ion binding|sodium-dependent phosphate transmembrane transporter activity|sodium:phosphate symporter activity		SLC34A2/ROS1(14)	breast(1)|cervix(1)|endometrium(5)|kidney(1)|large_intestine(9)|lung(18)|ovary(1)|prostate(1)|skin(4)	41		Breast(46;0.0503)				CCCAGATCTTCTGAAAGTCATCA	0.493			T	ROS1	NSCLC								19	190	---	---	---	---					
LOC101928622	101928622	broad.mit.edu	37	4	33883559	33883559	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:33883559delC	ENST00000506650.1	+	0	57																											agggaatatacccagatctta	0.413													2	4	---	---	---	---					
RP11-625I7.1	0	broad.mit.edu	37	4	78401200	78401201	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:78401200_78401201insA	ENST00000513871.1	-	0	122																											ctggatagaacaaaaaggcaga	0.426													2	4	---	---	---	---					
LINC01088	100505875	broad.mit.edu	37	4	80015183	80015183	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:80015183delA	ENST00000509088.1	+	0	349				RP11-438E5.1_ENST00000513153.1_RNA|RP11-438E5.1_ENST00000510667.1_RNA	NR_038342.1																						ttaagtgtctaatacattatt	0.318													2	4	---	---	---	---					
FAM13A-AS1	285512	broad.mit.edu	37	4	89638525	89638526	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:89638525_89638526insT	ENST00000500765.1	+	0	640					NR_002806.2																						gctgattggagtttttttctct	0.386													2	4	---	---	---	---					
LOC100507053	100507053	broad.mit.edu	37	4	100116939	100116940	+	RNA	INS	-	-	T	rs113460633		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:100116939_100116940insT	ENST00000500358.2	+	0	3714				RP11-696N14.1_ENST00000506454.1_RNA|RP11-696N14.1_ENST00000506160.1_RNA	NR_037884.1																						TCAGGATATAAttttttttttt	0.436													3	5	---	---	---	---					
LOC256880	256880	broad.mit.edu	37	4	100979806	100979806	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:100979806delG	ENST00000515026.1	+	0	729																											TAATCAGTGTGGAAAAAGGTT	0.438													2	4	---	---	---	---					
RP11-297P16.3	0	broad.mit.edu	37	4	104505224	104505224	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:104505224delT	ENST00000502936.1	+	0	189				RP11-297P16.3_ENST00000512401.1_RNA																							tttttatgcatttgtctttta	0.294													2	4	---	---	---	---					
LOC101929468	101929468	broad.mit.edu	37	4	105525174	105525174	+	RNA	DEL	T	T	-	rs58379600		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:105525174delT	ENST00000500179.1	+	0	96																											tggaatgttctttgtgtgtct	0.413													3	3	---	---	---	---					
LOC101929468	101929468	broad.mit.edu	37	4	105538437	105538438	+	RNA	DEL	TT	TT	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:105538437_105538438delTT	ENST00000500179.1	+	0	96																											tgaatctttctttttttttttt	0.322													2	4	---	---	---	---					
LEF1-AS1	641518	broad.mit.edu	37	4	109098849	109098850	+	RNA	DEL	TG	TG	-	rs34287601		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:109098849_109098850delTG	ENST00000507799.1	+	0	360				LEF1-AS1_ENST00000512129.1_RNA																							cacacacacatgcacacacaca	0.530													2	4	---	---	---	---					
CTD-2325B11.1	0	broad.mit.edu	37	4	125081541	125081541	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:125081541delA	ENST00000507299.1	-	0	262																											TATTATGAGTAATTGCTTTTT	0.279													2	4	---	---	---	---					
RP11-404I7.2	0	broad.mit.edu	37	4	133859999	133859999	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:133859999delC	ENST00000509628.1	-	0	32																											tgtgttgctgcctacactcgg	0.473													2	4	---	---	---	---					
RP11-284M14.1	0	broad.mit.edu	37	4	143920028	143920028	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:143920028delA	ENST00000507826.1	-	0	354																											atgaagtcataaaggaagaca	0.363													2	4	---	---	---	---					
RP11-284M14.1	0	broad.mit.edu	37	4	144043634	144043635	+	RNA	INS	-	-	T	rs35768669		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:144043634_144043635insT	ENST00000507826.1	-	0	354																											cccaatcaggcttttttttttt	0.416													2	4	---	---	---	---					
RP11-526A4.1	0	broad.mit.edu	37	4	150615697	150615698	+	RNA	DEL	CA	CA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:150615697_150615698delCA	ENST00000511993.1	-	0	763				RP11-707F2.1_ENST00000505781.1_lincRNA																							CCCCTCCTTCCACACACACACA	0.356													2	4	---	---	---	---					
RP11-6C14.1	0	broad.mit.edu	37	4	160670071	160670073	+	RNA	DEL	AGA	AGA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:160670071_160670073delAGA	ENST00000513718.1	-	0	115																											gccaatatccagaaggtttttct	0.414													5	3	---	---	---	---					
LOC90768	90768	broad.mit.edu	37	4	182908948	182908951	+	RNA	DEL	TTTT	TTTT	-	rs139719737		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:182908948_182908951delTTTT	ENST00000507869.1	-	0	512				AC108142.1_ENST00000509012.1_RNA																							GAGAGATATCTTTTCTTTCTGGAT	0.373													4	5	---	---	---	---					
LINC01060	401164	broad.mit.edu	37	4	189455200	189455201	+	RNA	DEL	TA	TA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr4:189455200_189455201delTA	ENST00000510832.1	+	0	617																											CCCTTTGACTTATCTTTCATGG	0.490													2	4	---	---	---	---					
RP11-445O3.1	0	broad.mit.edu	37	5	4516439	4516442	+	RNA	DEL	ACAC	ACAC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:4516439_4516442delACAC	ENST00000503188.1	+	0	1226_1229				RP11-445O3.2_ENST00000507435.1_lincRNA																							CGCATGAGCAacacacacacacac	0.377													2	4	---	---	---	---					
GUSBP1	728411	broad.mit.edu	37	5	21521168	21521168	+	RNA	DEL	A	A	-	rs11367557		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:21521168delA	ENST00000607545.1	+	0	314					NR_027026.1																						gcccttttgcaggctgcagac	0.448													2	4	---	---	---	---					
GUSBP1	728411	broad.mit.edu	37	5	21534245	21534246	+	RNA	INS	-	-	TG	rs143137704		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:21534245_21534246insTG	ENST00000607545.1	+	0	314					NR_027026.1																						GCAGGTGTGTCTGTCACAAACA	0.520													4	7	---	---	---	---					
GUSBP1	728411	broad.mit.edu	37	5	21558318	21558322	+	RNA	DEL	GTTTA	GTTTA	-	rs2354609		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:21558318_21558322delGTTTA	ENST00000607545.1	+	0	314					NR_027026.1																						TCCGTTGGTTGTTTAGTTTATTCCT	0.346													6	7	---	---	---	---					
CTD-2066L21.3	0	broad.mit.edu	37	5	33294705	33294706	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:33294705_33294706insA	ENST00000510327.1	-	0	179																											ggtcaaattacaaaaactaaag	0.262													2	4	---	---	---	---					
LIFR-AS1	100506495	broad.mit.edu	37	5	38595830	38595832	+	RNA	DEL	TTT	TTT	-	rs70978897		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:38595830_38595832delTTT	ENST00000500733.2	+	0	2540				LIFR-AS1_ENST00000500817.2_RNA	NR_037423.1|NR_103553.1																						ACAATAGGTCttttttttttttt	0.453													2	4	---	---	---	---					
LOC100506674	100506674	broad.mit.edu	37	5	44800185	44800186	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:44800185_44800186insT	ENST00000503179.1	-	0	118				RP11-53O19.1_ENST00000508123.1_RNA|RP11-53O19.1_ENST00000514597.1_RNA|RP11-53O19.1_ENST00000508945.1_RNA|RP11-53O19.1_ENST00000503452.1_RNA|RP11-53O19.1_ENST00000505401.1_RNA|RP11-53O19.1_ENST00000505302.1_RNA|RP11-53O19.1_ENST00000505637.1_RNA																							TGAATTCTTGATTTTTTTTCTC	0.396													2	4	---	---	---	---					
CTD-2288O8.1	0	broad.mit.edu	37	5	52013870	52013871	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:52013870_52013871insT	ENST00000502995.1	-	0	167																											attcctttatgtttttttaatg	0.332													2	4	---	---	---	---					
CTC-365E16.1	0	broad.mit.edu	37	5	71657269	71657270	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:71657269_71657270insC	ENST00000606310.1	+	0	753_754																											acacatagcttccccacagcat	0.495													2	4	---	---	---	---					
CTD-2269F5.1	0	broad.mit.edu	37	5	83764635	83764636	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:83764635_83764636insG	ENST00000509406.1	+	0	458																											CCATTTCTTCTGGGGGAAAACA	0.342													2	4	---	---	---	---					
RP11-133F8.2	0	broad.mit.edu	37	5	91951345	91951346	+	RNA	DEL	AG	AG	-	rs34141820		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:91951345_91951346delAG	ENST00000512210.1	-	0	52																											TATGGAAGAAAGCATTAGATGT	0.446													2	4	---	---	---	---					
CTD-2337A12.1	0	broad.mit.edu	37	5	95309708	95309709	+	RNA	DEL	CA	CA	-	rs113896907		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:95309708_95309709delCA	ENST00000511775.1	+	0	35				CTD-2337A12.1_ENST00000502645.2_RNA|AC008592.7_ENST00000506070.1_lincRNA																							AATTTGcacgcacacacacaca	0.450													3	3	---	---	---	---					
SLC27A6	28965	broad.mit.edu	37	5	128070443	128070443	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:128070443delA	ENST00000514867.1	+	0	69																											ggttttacctaaaaccgccac	0.398													2	4	---	---	---	---					
NPY6R	4888	broad.mit.edu	37	5	137138924	137138925	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:137138924_137138925insA	ENST00000510937.1	+	0	260					NR_002713.3																						AAATGGTAAGGAAAAAAACAGA	0.371													2	4	---	---	---	---					
CTB-57H20.1	0	broad.mit.edu	37	5	143092225	143092225	+	RNA	DEL	A	A	-	rs78849212		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:143092225delA	ENST00000503323.1	+	0	379																											CAATTCGGAGAAAAAAAAGGA	0.423													4	5	---	---	---	---					
RP11-541P9.3	0	broad.mit.edu	37	5	162453166	162453166	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:162453166delG	ENST00000458002.2	-	0	424																											tgataggataggtagagagaa	0.423													2	4	---	---	---	---					
RP11-541P9.3	0	broad.mit.edu	37	5	162531461	162531461	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:162531461delC	ENST00000509211.1	-	0	117				RP11-541P9.3_ENST00000458002.2_RNA																							ATTTTTCCCTCCTTGCGAGTT	0.393													2	4	---	---	---	---					
RP11-541P9.3	0	broad.mit.edu	37	5	162757780	162757781	+	RNA	DEL	AA	AA	-	rs145791371		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:162757780_162757781delAA	ENST00000503504.1	-	0	355				RP11-541P9.3_ENST00000458002.2_RNA																							actctgtctcaaaaaaaaaaaa	0.450													2	4	---	---	---	---					
LOC102546299	102546299	broad.mit.edu	37	5	163735211	163735211	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:163735211delT	ENST00000524297.1	+	0	228				CTC-340A15.2_ENST00000517508.1_RNA|CTC-340A15.2_ENST00000523704.1_RNA|CTC-340A15.2_ENST00000522646.1_RNA|CTC-340A15.2_ENST00000522686.1_RNA|CTC-340A15.2_ENST00000522303.1_RNA|CTC-340A15.2_ENST00000519570.1_RNA|CTC-340A15.2_ENST00000523648.1_RNA																							ATATAACTGCTTTTTTTTTTG	0.313													2	4	---	---	---	---					
CTC-535M15.2	0	broad.mit.edu	37	5	164986979	164986979	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:164986979delT	ENST00000522189.1	+	0	21																											ggtgtggtggtttccttctgt	0.443													2	4	---	---	---	---					
LINC01187	100507267	broad.mit.edu	37	5	169625470	169625475	+	RNA	DEL	ATTCCT	ATTCCT	-	rs10581962		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:169625470_169625475delATTCCT	ENST00000506431.2	-	0	670_675																											cagtggttgaattcctattcctcaag	0.417													2	4	---	---	---	---					
CTD-2532K18.1	0	broad.mit.edu	37	5	174245012	174245013	+	RNA	DEL	GT	GT	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:174245012_174245013delGT	ENST00000502684.1	+	0	50																											ttataatatggtgtgtgtgtgt	0.431													3	4	---	---	---	---					
AACSP1	729522	broad.mit.edu	37	5	178202083	178202084	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr5:178202083_178202084insG	ENST00000503486.2	-	0	852					NR_024035.1																						GCACACCAGCCGGGGGGCGGTG	0.634													2	4	---	---	---	---					
RP11-532F6.4	0	broad.mit.edu	37	6	733501	733501	+	RNA	DEL	T	T	-	rs137899133		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:733501delT	ENST00000607644.1	+	0	243																											AGGGAAGCTATTTTTTTTTTT	0.353													2	4	---	---	---	---					
LY86-AS1	285780	broad.mit.edu	37	6	6430459	6430460	+	RNA	INS	-	-	AAAC	rs70975978	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:6430459_6430460insAAAC	ENST00000435641.1	-	0	639				LY86-AS1_ENST00000429345.1_RNA|LY86-AS1_ENST00000447858.1_RNA																							taaaaaaatcaaaacaaacaaa	0.351													7	1	---	---	---	---					
RP11-146I2.1	0	broad.mit.edu	37	6	15059048	15059049	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:15059048_15059049insT	ENST00000437648.1	-	0	426																											aaataacattcttttttttttt	0.416													3	4	---	---	---	---					
RP1-167F1.2	0	broad.mit.edu	37	6	19749646	19749646	+	RNA	DEL	T	T	-	rs35027296		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:19749646delT	ENST00000432171.2	-	0	263				RP3-471C18.2_ENST00000424083.1_lincRNA																							AATTGGATTATTTTTTTTTTA	0.373													2	4	---	---	---	---					
RP11-239H6.2	0	broad.mit.edu	37	6	20300667	20300668	+	RNA	DEL	AC	AC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:20300667_20300668delAC	ENST00000449143.2	+	0	191																											tactaaaagtacacacacacac	0.515													3	3	---	---	---	---					
RP1-209A6.1	0	broad.mit.edu	37	6	22810339	22810340	+	RNA	DEL	CA	CA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:22810339_22810340delCA	ENST00000420572.2	-	0	197																											TACACACACGCACACACACACA	0.416													2	4	---	---	---	---					
HCG20	414774	broad.mit.edu	37	6	30755440	30755440	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:30755440delA	ENST00000439406.1	+	0	127																											tgtctctactaaaagtacaaa	0.562													6	0	---	---	---	---					
RP1-90K10.4	0	broad.mit.edu	37	6	36911291	36911291	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:36911291delA	ENST00000427609.2	-	0	204																											tctcaggaataaaaaaaaaaa	0.303													4	1	---	---	---	---					
GSTA9P	100174857	broad.mit.edu	37	6	52807920	52807920	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:52807920delT	ENST00000448991.1	-	0	230																											CCAAGAATGGttttttttttt	0.507													3	2	---	---	---	---					
RP11-154D6.1	0	broad.mit.edu	37	6	72027450	72027453	+	RNA	DEL	ACAG	ACAG	-	rs72450664		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:72027450_72027453delACAG	ENST00000589255.1	-	0	240				RP11-154D6.1_ENST00000586232.1_RNA|RP11-154D6.1_ENST00000590780.1_RNA|RP11-154D6.1_ENST00000591156.1_RNA|RP11-154D6.1_ENST00000585882.1_RNA|RP11-154D6.1_ENST00000586030.1_RNA|RP11-154D6.1_ENST00000590213.1_RNA|RP11-154D6.1_ENST00000587036.1_RNA|RP11-154D6.1_ENST00000585945.1_RNA|RP11-154D6.1_ENST00000588612.1_RNA|RP11-154D6.1_ENST00000587015.1_RNA|RP11-154D6.1_ENST00000587397.1_RNA|RP11-154D6.1_ENST00000587253.1_RNA|RP11-154D6.1_ENST00000434683.1_RNA|RP11-154D6.1_ENST00000450998.1_RNA|RP3-331H24.5_ENST00000602823.1_lincRNA																							tataccaataacagacagacagcc	0.343													4	3	---	---	---	---					
LOC101928516	101928516	broad.mit.edu	37	6	74849495	74849496	+	RNA	INS	-	-	CC			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:74849495_74849496insCC	ENST00000435946.1	+	0	138																											catctggcattcccccctgctt	0.455													2	4	---	---	---	---					
LOC101927640	101927640	broad.mit.edu	37	6	112629375	112629376	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:112629375_112629376insC	ENST00000587816.1	+	0	111				RP11-506B6.6_ENST00000585504.1_RNA|RP11-506B6.6_ENST00000585611.1_RNA|RP11-506B6.6_ENST00000590673.1_RNA																							ATTTCTCACTGCCCCCCCTTCC	0.535													4	2	---	---	---	---					
LINC00271	100131814	broad.mit.edu	37	6	135978766	135978768	+	RNA	DEL	CTT	CTT	-	rs35786994		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:135978766_135978768delCTT	ENST00000421378.2	+	0	231					NR_026805.1																						GTCCCAAACACTTCTTGATGATT	0.360													5	2	---	---	---	---					
STXBP5-AS1	729178	broad.mit.edu	37	6	147256043	147256044	+	RNA	DEL	AC	AC	-	rs72302896		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr6:147256043_147256044delAC	ENST00000367477.3	-	0	695				STXBP5-AS1_ENST00000427394.1_RNA|STXBP5-AS1_ENST00000458125.1_RNA|STXBP5-AS1_ENST00000431143.1_RNA|STXBP5-AS1_ENST00000447072.1_RNA																							TCACAAGAATacacacacacac	0.332													3	3	---	---	---	---					
AC004485.3	0	broad.mit.edu	37	7	24261254	24261255	+	RNA	INS	-	-	ACTT	rs60472694	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:24261254_24261255insACTT	ENST00000439839.1	-	0	159																											tccagaaactgacttatacaca	0.416													4	2	---	---	---	---					
LOC646588	646588	broad.mit.edu	37	7	25699193	25699193	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:25699193delA	ENST00000446840.1	-	0	370																											CAGTACCTGGAAAAATTAAGG	0.358													2	4	---	---	---	---					
AC006380.1	0	broad.mit.edu	37	7	31356656	31356660	+	RNA	DEL	AAAAG	AAAAG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:31356656_31356660delAAAAG	ENST00000408824.1	+	0	45_49																											ttttgccattaaaagaaatgtcaaa	0.380													3	6	---	---	---	---					
RP11-340I6.7	0	broad.mit.edu	37	7	63353878	63353878	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:63353878delT	ENST00000587736.1	-	0	566																											CTGCAAGATATCCACCTGGAT	0.383													8	112	---	---	---	---					
RP5-945F2.3	0	broad.mit.edu	37	7	67651964	67651965	+	RNA	INS	-	-	T	rs71074110		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:67651964_67651965insT	ENST00000446187.1	-	0	317																											ttgttcttctattttttttttt	0.312													3	6	---	---	---	---					
COL26A1	136227	broad.mit.edu	37	7	101104589	101104590	+	RNA	INS	-	-	T	rs143066422	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:101104589_101104590insT	ENST00000313669.7	+	0	577				COL26A1_ENST00000397927.3_RNA|COL26A1_ENST00000528707.1_RNA	NM_133457.2	NP_597714.2			collagen, type XXVI, alpha 1																		CCTCCTCCttctttttttttga	0.540													3	2	---	---	---	---					
COL26A1	136227	broad.mit.edu	37	7	101133981	101133982	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:101133981_101133982insA	ENST00000313669.7	+	0	577				COL26A1_ENST00000397927.3_RNA|COL26A1_ENST00000528707.1_RNA	NM_133457.2	NP_597714.2			collagen, type XXVI, alpha 1																		gactctatctcaaaaaaaaaGG	0.540													2	4	---	---	---	---					
LINC01392	104355291	broad.mit.edu	37	7	114858990	114858991	+	RNA	INS	-	-	TCTC	rs146707020	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:114858990_114858991insTCTC	ENST00000419883.1	-	0	173																											TGAGATCTCTTTCTCTTTCTCT	0.391													4	5	---	---	---	---					
AC008060.8	0	broad.mit.edu	37	7	155226179	155226180	+	RNA	DEL	CT	CT	-	rs116602889	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr7:155226179_155226180delCT	ENST00000419225.1	-	0	266																											cacctcccccctctctctctct	0.579													2	4	---	---	---	---					
ERICH1-AS1	619343	broad.mit.edu	37	8	770607	770607	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:770607delC	ENST00000522092.1	+	0	175				ERICH1-AS1_ENST00000577187.1_RNA	NR_073397.1|NR_073466.1																						CTATTTTTTTCCACCAGAGGC	0.348													2	4	---	---	---	---					
ERICH1-AS1	619343	broad.mit.edu	37	8	1021355	1021355	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:1021355delA	ENST00000522092.1	+	0	332				ERICH1-AS1_ENST00000578889.1_RNA	NR_073397.1|NR_073466.1																						CTTGACTTTCAAGGGTGGCTT	0.567													2	4	---	---	---	---					
AC021613.1	0	broad.mit.edu	37	8	21013660	21013663	+	RNA	DEL	TGTG	TGTG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:21013660_21013663delTGTG	ENST00000401126.2	+	0	19_22																											ctcaatactatgtgtgtgtgtgtg	0.373													3	5	---	---	---	---					
RP11-17A4.4	0	broad.mit.edu	37	8	57563985	57563986	+	RNA	DEL	AG	AG	-	rs36050163		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:57563985_57563986delAG	ENST00000521215.1	-	0	316																											aggaactgacagagtgagagct	0.535													5	3	---	---	---	---					
RP11-1112C15.1	0	broad.mit.edu	37	8	58891190	58891190	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:58891190delA	ENST00000522992.1	+	0	127																											gttgtctgttaaaatctgttg	0.318													2	4	---	---	---	---					
LOC102724623	102724623	broad.mit.edu	37	8	64959952	64959953	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:64959952_64959953insT	ENST00000524360.1	-	0	195				RP11-32K4.1_ENST00000523191.1_RNA|RP11-32K4.1_ENST00000521958.1_RNA																							GAGAATTACCGTTTTTTATTCA	0.302													2	4	---	---	---	---					
LINC01592	100505718	broad.mit.edu	37	8	69843571	69843572	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:69843571_69843572insG	ENST00000518540.1	-	0	520					NR_039986.1																						acttctcttgaggggagacaat	0.411													2	4	---	---	---	---					
ZFHX4-AS1	100192378	broad.mit.edu	37	8	77548527	77548527	+	RNA	DEL	A	A	-	rs80118697		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:77548527delA	ENST00000518143.1	-	0	434				ZFHX4-AS1_ENST00000522961.1_RNA	NR_024360.1																						aattaaaaccaaaaaaaaaag	0.239													2	4	---	---	---	---					
RP11-653B10.1	0	broad.mit.edu	37	8	83446290	83446290	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:83446290delA	ENST00000522776.1	-	0	262																											tggggcatttagcccatttac	0.378													2	4	---	---	---	---					
RP11-653B10.1	0	broad.mit.edu	37	8	83446470	83446470	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:83446470delT	ENST00000522776.1	-	0	262																											tagtgcttcctttttttttta	0.403													2	4	---	---	---	---					
LOC101927141	101927141	broad.mit.edu	37	8	83851457	83851457	+	RNA	DEL	A	A	-	rs75589126		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:83851457delA	ENST00000522123.1	-	0	57				CTD-2272D18.1_ENST00000524359.1_lincRNA																							aacaatgattaaaaaaaaaaa	0.308													2	4	---	---	---	---					
RP11-120I21.2	0	broad.mit.edu	37	8	85046811	85046812	+	RNA	INS	-	-	T	rs66838730		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:85046811_85046812insT	ENST00000523678.1	+	0	279																											AGCTGCAAttcttttttttttt	0.455													2	4	---	---	---	---					
RP11-586K2.1	0	broad.mit.edu	37	8	89510915	89510915	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:89510915delT	ENST00000521433.1	+	0	179				RP11-586K2.1_ENST00000523254.1_RNA																							ACATTACttctttttttttta	0.318													2	4	---	---	---	---					
RP11-122C21.1	0	broad.mit.edu	37	8	92756466	92756466	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:92756466delA	ENST00000518416.1	-	0	415																											cagaagcaataaaaaaAAAAA	0.403													2	4	---	---	---	---					
LINC00535	642924	broad.mit.edu	37	8	94372825	94372826	+	RNA	DEL	AC	AC	-	rs33962637		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:94372825_94372826delAC	ENST00000501400.1	-	0	1474				LINC00535_ENST00000520096.1_RNA	NR_033858.1																						AAAAAGacatacacacacacac	0.391													2	4	---	---	---	---					
LINC00536	100859921	broad.mit.edu	37	8	117135575	117135575	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:117135575delT	ENST00000505156.2	-	0	1463					NR_046215.1																						GCTTCCCAGCttttttttttt	0.502													3	5	---	---	---	---					
CCDC26	137196	broad.mit.edu	37	8	130387972	130387985	+	RNA	DEL	TGTGTGTGTGTGTG	TGTGTGTGTGTGTG	-	rs138150886		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:130387972_130387985delTGTGTGTGTGTGTG	ENST00000446592.3	-	0	360																											ttgcattgtatgtgtgtgtgtgtgtgtgtgtgtg	0.360													2	4	---	---	---	---					
CCDC26	137196	broad.mit.edu	37	8	130482199	130482199	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr8:130482199delA	ENST00000446592.3	-	0	360																											tctctctctcaaaaaaaaaGG	0.403													2	4	---	---	---	---					
LINC00583	100113404	broad.mit.edu	37	9	13938906	13938906	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:13938906delT	ENST00000381010.3	+	0	91					NR_038194.1																						GTGAAGAGGCTTTTTTTTTCA	0.378													2	4	---	---	---	---					
MIR31HG	554202	broad.mit.edu	37	9	21514747	21514747	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:21514747delA	ENST00000304425.3	-	0	181					NR_027054.1																						AAATGCTGACAAAAAAATGCC	0.299													2	4	---	---	---	---					
RP11-764K9.1	0	broad.mit.edu	37	9	68405348	68405349	+	RNA	INS	-	-	T	rs149727388	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:68405348_68405349insT	ENST00000417843.2	-	0	224																											aaaattctcaataaatgaggta	0.312													7	32	---	---	---	---					
RP11-305L7.3	0	broad.mit.edu	37	9	93921646	93921647	+	RNA	INS	-	-	AGGAAAGAG	rs59115110		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:93921646_93921647insAGGAAAGAG	ENST00000457976.1	-	0	83																											ggaaggaaggaaagaaagagag	0.510													2	4	---	---	---	---					
LINC01492	101928496	broad.mit.edu	37	9	105911005	105911005	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:105911005delT	ENST00000411575.1	-	0	941																											ctttttacagtttttggctca	0.318													2	4	---	---	---	---					
RP11-202G18.1	0	broad.mit.edu	37	9	114043911	114043911	+	RNA	DEL	T	T	-	rs11368157		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr9:114043911delT	ENST00000426204.1	-	0	217																											CCCATCAGCAttttttttttt	0.458													3	3	---	---	---	---					
RP11-342D11.3	0	broad.mit.edu	37	10	33386434	33386435	+	RNA	DEL	TA	TA	-	rs150406042		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:33386434_33386435delTA	ENST00000414308.1	-	0	202																											tttgcaTTCTTATATGTTTTAA	0.396													4	3	---	---	---	---					
ANTXRLP1	100996567	broad.mit.edu	37	10	47630034	47630034	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:47630034delT	ENST00000454837.1	-	0	291					NR_103827.1																						ctgctccaacttttttcctcc	0.418													2	4	---	---	---	---					
RP11-170M17.1	0	broad.mit.edu	37	10	65591069	65591070	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:65591069_65591070insT	ENST00000444770.1	+	0	494																											GActctgtttcttttttttctc	0.371													2	4	---	---	---	---					
CTA-109P11.1	0	broad.mit.edu	37	10	119329923	119329923	+	RNA	DEL	G	G	-	rs75751695		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:119329923delG	ENST00000450247.1	-	0	162																											AAGTTGGCAAGGGGGAGTAGG	0.448													3	4	---	---	---	---					
DMBT1P1	375940	broad.mit.edu	37	10	124555371	124555371	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr10:124555371delA	ENST00000439464.2	+	0	3362					NR_003570.1																						AATTTAATACAAAAACCACCT	0.458													2	4	---	---	---	---					
SAA3P	6290	broad.mit.edu	37	11	18135968	18135969	+	RNA	INS	-	-	T	rs151309798	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:18135968_18135969insT	ENST00000534768.1	-	0	147					NR_026576.1															lung(2)	2						ggttctcaacctttgctgtgca	0.455													2	4	---	---	---	---					
LINC01495	102723378	broad.mit.edu	37	11	22473186	22473186	+	RNA	DEL	A	A	-	rs146684697		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:22473186delA	ENST00000532380.1	-	0	341																											GCTGTTGTTGAAAAAAAAAAA	0.328													3	4	---	---	---	---					
RP11-22P4.1	0	broad.mit.edu	37	11	28375573	28375573	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:28375573delT	ENST00000532947.1	+	0	52																											CCTCATATTCTAAGAGAGAAG	0.373													2	4	---	---	---	---					
LOC440040	440040	broad.mit.edu	37	11	49630929	49630929	+	RNA	DEL	T	T	-	rs59368430	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:49630929delT	ENST00000527477.1	+	0	1062																											TATCCAGAAATTTTTTTTTTT	0.383													3	3	---	---	---	---					
LOC101927495	101927495	broad.mit.edu	37	11	61370734	61370735	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:61370734_61370735insG	ENST00000506329.2	+	0	293																											CACAGATGTGAGGGGGGAGGGT	0.594													2	4	---	---	---	---					
RP11-119D9.1	0	broad.mit.edu	37	11	67654840	67654842	+	RNA	DEL	TTC	TTC	-	rs35955393		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:67654840_67654842delTTC	ENST00000511677.1	+	0	194																											gatctaggcgttcttcttcttct	0.384													2	4	---	---	---	---					
LOC101928989	101928989	broad.mit.edu	37	11	81776665	81776666	+	RNA	INS	-	-	TT	rs141457283		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:81776665_81776666insTT	ENST00000500502.1	-	0	813																											ggatgcatttcttttttttttt	0.381													3	3	---	---	---	---					
LOC100506368	100506368	broad.mit.edu	37	11	86701696	86701697	+	RNA	DEL	AC	AC	-	rs71939983		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:86701696_86701697delAC	ENST00000499504.3	+	0	139					NR_038905.1																						catagcttgtacacacacacac	0.406													3	4	---	---	---	---					
RP11-164N3.3	0	broad.mit.edu	37	11	87834215	87834215	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:87834215delT	ENST00000528458.1	+	0	138																											TGACATCAGGTTTTTGGTGTC	0.388													2	4	---	---	---	---					
FOLH1B	219595	broad.mit.edu	37	11	89385933	89385937	+	RNA	DEL	TATTT	TATTT	-	rs67101267		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:89385933_89385937delTATTT	ENST00000532352.1	+	0	402							Q9HBA9	FOH1B_HUMAN	folate hydrolase 1B						proteolysis	cytoplasm	dipeptidase activity|metal ion binding|metallopeptidase activity			breast(1)|central_nervous_system(1)|endometrium(1)|kidney(2)|large_intestine(7)|lung(26)|ovary(4)|skin(4)|urinary_tract(2)	48						ATATTGATTATATTTTATTAATGGT	0.293													3	3	---	---	---	---					
DISC1FP1	101929222	broad.mit.edu	37	11	90230804	90230805	+	RNA	DEL	CA	CA	-	rs149973660		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:90230804_90230805delCA	ENST00000562678.1	+	0	43																											ggaatttgtccatctcttctag	0.337													4	3	---	---	---	---					
DISC1FP1	101929222	broad.mit.edu	37	11	90235921	90235922	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:90235921_90235922insT	ENST00000562678.1	+	0	43																											GGTAGTTTAGCTTTTTTCATGA	0.332													5	2	---	---	---	---					
DISC1FP1	101929222	broad.mit.edu	37	11	90329740	90329740	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:90329740delT	ENST00000562678.1	+	0	185																											AAGGGAATCATTTTCTTTCAC	0.363													2	4	---	---	---	---					
DISC1FP1	101929222	broad.mit.edu	37	11	90433563	90433563	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:90433563delA	ENST00000562678.1	+	0	185																											AGTTATTTATAAGAATCTACT	0.303													2	4	---	---	---	---					
RP11-360K13.1	0	broad.mit.edu	37	11	96487720	96487721	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:96487720_96487721insC	ENST00000527528.1	+	0	158																											atcctccctcaccccccaacac	0.436													2	4	---	---	---	---					
RP11-563P16.1	0	broad.mit.edu	37	11	103622997	103623000	+	RNA	DEL	AATG	AATG	-	rs71822712		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:103622997_103623000delAATG	ENST00000533459.1	-	0	127																											AACAAGgaataatgaatgaatgaa	0.412													4	6	---	---	---	---					
RP11-262A12.1	0	broad.mit.edu	37	11	109624725	109624726	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:109624725_109624726insG	ENST00000534252.2	-	0	542																											ATGGTCAGCTTGGGGGGGTATA	0.475													2	4	---	---	---	---					
LOC283140	283140	broad.mit.edu	37	11	112213419	112213420	+	RNA	INS	-	-	T	rs34286682		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:112213419_112213420insT	ENST00000504610.2	+	0	238																											cacctagctaattttttttttt	0.505													2	4	---	---	---	---					
LOC100507431	100507431	broad.mit.edu	37	11	130730404	130730405	+	RNA	INS	-	-	T	rs72459859	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr11:130730404_130730405insT	ENST00000533812.2	-	0	946																											gttttgttttgtttttttttgt	0.431													2	4	---	---	---	---					
RP11-114G22.1	0	broad.mit.edu	37	12	23147990	23147990	+	RNA	DEL	A	A	-	rs58639198		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:23147990delA	ENST00000540895.1	+	0	508																											TTTTCCCCAGAAAAGCTCTAT	0.403													3	3	---	---	---	---					
RP11-444D3.1	0	broad.mit.edu	37	12	24607816	24607816	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:24607816delT	ENST00000538905.1	-	0	45																											CAGGAAAGAATATTAAGACAT	0.303													2	4	---	---	---	---					
LINC00477	144360	broad.mit.edu	37	12	24728697	24728697	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:24728697delA	ENST00000483544.1	-	0	1213					NR_029451.2																						acaaaaaaagaaaaaaaaaag	0.383													2	4	---	---	---	---					
RP11-625L16.1	0	broad.mit.edu	37	12	24866626	24866626	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:24866626delT	ENST00000536131.1	+	0	192																											TTAGTCCTCCTTTTTTTTTTC	0.458													3	6	---	---	---	---					
RP11-283G6.4	0	broad.mit.edu	37	12	26469285	26469286	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:26469285_26469286insA	ENST00000540392.1	-	0	130				RP11-283G6.5_ENST00000540625.1_RNA|RP11-612B6.1_ENST00000539552.1_lincRNA																							cactggggtacaaaaaaaaacc	0.545													2	4	---	---	---	---					
RP11-847H18.3	0	broad.mit.edu	37	12	34200729	34200730	+	RNA	INS	-	-	AGG	rs149021494	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:34200729_34200730insAGG	ENST00000537655.1	+	0	211																											gtctagtttgcagaagtttctg	0.515													4	2	---	---	---	---					
RP5-1057I20.2	0	broad.mit.edu	37	12	48227397	48227398	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:48227397_48227398insG	ENST00000550909.1	+	0	105																											GCAGGTGGGCAGGGGGGTGTCC	0.624													2	4	---	---	---	---					
LOC102724050	102724050	broad.mit.edu	37	12	54827689	54827690	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:54827689_54827690insT	ENST00000550474.1	+	0	116				RP11-753H16.5_ENST00000552785.1_RNA																							ttatttATTCAttttttttttg	0.490													3	3	---	---	---	---					
RP11-150C16.1	0	broad.mit.edu	37	12	59396517	59396518	+	RNA	INS	-	-	T	rs59197497		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:59396517_59396518insT	ENST00000547590.1	+	0	226																											TTTCTTTCTGATTTTTTTTTTT	0.356													2	4	---	---	---	---					
RP11-123O10.4	0	broad.mit.edu	37	12	67311757	67311758	+	RNA	DEL	GA	GA	-	rs111909371		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:67311757_67311758delGA	ENST00000535721.1	-	0	113																											cacacacacGgagagagagaga	0.426													2	4	---	---	---	---					
RP11-123O10.4	0	broad.mit.edu	37	12	67386322	67386323	+	RNA	DEL	AT	AT	-	rs72524413		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:67386322_67386323delAT	ENST00000535721.1	-	0	113																											aagATAAGACATGTGctatcaa	0.351													4	4	---	---	---	---					
RP11-335O4.1	0	broad.mit.edu	37	12	67967015	67967016	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:67967015_67967016insG	ENST00000540761.1	-	0	273																											ATGAACAGTTTGGGGGGGACAT	0.396													2	4	---	---	---	---					
RP11-314D7.4	0	broad.mit.edu	37	12	73648870	73648870	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:73648870delG	ENST00000549058.1	-	0	306																											tggccatagtggcaggaatgg	0.512													2	4	---	---	---	---					
RP11-54A9.1	0	broad.mit.edu	37	12	76679547	76679548	+	RNA	INS	-	-	T	rs111905363		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:76679547_76679548insT	ENST00000553247.1	+	0	77																											ACTATGGTTTGTTTTTTTTTTT	0.416													2	4	---	---	---	---					
RP11-511B23.2	0	broad.mit.edu	37	12	93578035	93578036	+	RNA	DEL	GT	GT	-	rs61096511		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:93578035_93578036delGT	ENST00000547432.1	-	0	316				RP11-511B23.2_ENST00000549930.1_RNA																							gacagacagagtgtgtgtgtgt	0.480													2	4	---	---	---	---					
RP11-511B23.2	0	broad.mit.edu	37	12	93583146	93583146	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:93583146delT	ENST00000547432.1	-	0	316				RP11-511B23.2_ENST00000549930.1_RNA																							cattttctacttttactctct	0.299													2	4	---	---	---	---					
RP11-328J6.1	0	broad.mit.edu	37	12	103520442	103520443	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:103520442_103520443insA	ENST00000548594.1	-	0	167				RP11-328J6.1_ENST00000548415.1_RNA																							tgaagttaactaaaaaAAAAAA	0.317													2	4	---	---	---	---					
RP11-797M17.1	0	broad.mit.edu	37	12	107512583	107512597	+	RNA	DEL	TGTTTGCCAAGGGTT	TGTTTGCCAAGGGTT	-	rs113939106		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:107512583_107512597delTGTTTGCCAAGGGTT	ENST00000547679.1	+	0	127																											GCCTGAACAGTGTTTGCCAAGGGTTTGTTTGCCAA	0.516													3	3	---	---	---	---					
RP4-601P9.2	0	broad.mit.edu	37	12	115184901	115184902	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:115184901_115184902insC	ENST00000551875.1	+	0	541																											TTCTCTCCCAGCCCCCACATGG	0.649													2	4	---	---	---	---					
RP11-897M7.1	0	broad.mit.edu	37	12	131964557	131964557	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr12:131964557delT	ENST00000535133.1	-	0	195																											tttccgtcacttacaatggaa	0.383													2	4	---	---	---	---					
LINC00457	100874179	broad.mit.edu	37	13	35039556	35039556	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr13:35039556delT	ENST00000605909.1	+	0	170																											TCTTTCATTATTTATGAAAGA	0.403													2	4	---	---	---	---					
LINC00368	101927802	broad.mit.edu	37	13	111754309	111754309	+	RNA	DEL	T	T	-	rs34252111		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr13:111754309delT	ENST00000422994.1	+	0	250																											aaaaaaaaaattcataataca	0.502													3	3	---	---	---	---					
CTD-2591A6.2	0	broad.mit.edu	37	14	28851085	28851086	+	RNA	INS	-	-	AC	rs34008238	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:28851085_28851086insAC	ENST00000548280.1	+	0	392																											TATGTGTGCTTacacacacaca	0.307													4	3	---	---	---	---					
FOXG1-AS1	103695363	broad.mit.edu	37	14	29227587	29227588	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:29227587_29227588insG	ENST00000551395.1	-	0	278				RP11-966I7.1_ENST00000549487.1_RNA|RP11-966I7.1_ENST00000546560.1_RNA																							TTAAAAAGATAGGGGGAAAAGA	0.376													2	4	---	---	---	---					
CTD-2251F13.1	0	broad.mit.edu	37	14	30756751	30756752	+	RNA	INS	-	-	TG	rs72235466	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:30756751_30756752insTG	ENST00000508469.2	-	0	69																											ttccaatattatgtgtgtgtgt	0.337													3	3	---	---	---	---					
RP11-58E21.5	0	broad.mit.edu	37	14	50519464	50519465	+	RNA	DEL	AC	AC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:50519464_50519465delAC	ENST00000556019.2	-	0	186																											gcacacacagacacacacacac	0.495													2	4	---	---	---	---					
RP11-433J8.2	0	broad.mit.edu	37	14	97222125	97222126	+	RNA	INS	-	-	CA	rs10544450	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:97222125_97222126insCA	ENST00000556669.1	+	0	188																											GCTCAAAAATTcacacacacac	0.500													2	4	---	---	---	---					
LOC100129345	100129345	broad.mit.edu	37	14	98134690	98134691	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr14:98134690_98134691insA	ENST00000355909.3	-	0	414					NR_033943.1																						ATCTTAGTCAGACCCATAGTTG	0.421													2	4	---	---	---	---					
LOC101927079	101927079	broad.mit.edu	37	15	22336541	22336541	+	RNA	DEL	A	A	-	rs141660071		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:22336541delA	ENST00000558896.1	+	0	583																											tttttttactatttttttaat	0.299													6	4	---	---	---	---					
PWRN1	791114	broad.mit.edu	37	15	24827534	24827534	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:24827534delT	ENST00000568609.1	+	0	1230					NR_026646.1																						tccagtcCCCTTTCATATTTA	0.378													2	4	---	---	---	---					
CTD-2022H16.1	0	broad.mit.edu	37	15	30362894	30362895	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:30362894_30362895insT	ENST00000421447.1	-	0	445																											TTCCATGCCAGttttttttttt	0.490													2	4	---	---	---	---					
LOC101928174	101928174	broad.mit.edu	37	15	35102322	35102322	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:35102322delA	ENST00000503496.1	+	0	299																											gcttattactaaatacgcaca	0.403													2	4	---	---	---	---					
RP11-507B12.2	0	broad.mit.edu	37	15	61774823	61774824	+	RNA	INS	-	-	AA	rs35332157	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:61774823_61774824insAA	ENST00000559783.1	-	0	186																											ttatattagggaaaaaagacta	0.302													5	1	---	---	---	---					
PCAT29	104472713	broad.mit.edu	37	15	69900712	69900712	+	RNA	DEL	A	A	-	rs35858681		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:69900712delA	ENST00000558411.1	+	0	185																											actccaactcaaaaaaaaaaa	0.488													3	2	---	---	---	---					
DNM1P35	100128285	broad.mit.edu	37	15	76022680	76022681	+	RNA	INS	-	-	G	rs140139668	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:76022680_76022681insG	ENST00000501931.1	-	0	517_518					NR_024595.3																						GAAGGAATATTGGGGGGGGGTG	0.574													3	4	---	---	---	---					
CTD-2034I4.1	0	broad.mit.edu	37	15	81836011	81836013	+	RNA	DEL	TTG	TTG	-	rs113661396		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:81836011_81836013delTTG	ENST00000559211.1	+	0	98																											ttttgttgttttgttgttgttgt	0.448													3	4	---	---	---	---					
LOC101926928	101926928	broad.mit.edu	37	15	92014350	92014351	+	RNA	INS	-	-	AC	rs142279523	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:92014350_92014351insAC	ENST00000554333.1	+	0	295																											gatacacatagacacacacaca	0.351													3	3	---	---	---	---					
CTD-2147F2.1	0	broad.mit.edu	37	15	97912350	97912350	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:97912350delT	ENST00000560314.1	+	0	443																											ATTTGAAGGGTTTTCATTTAA	0.289													2	4	---	---	---	---					
CTD-2544M6.1	0	broad.mit.edu	37	15	98728794	98728795	+	RNA	INS	-	-	T	rs74854263		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr15:98728794_98728795insT	ENST00000560360.1	-	0	291																											TGCCttttttcttttttttttt	0.441													3	5	---	---	---	---					
RP11-420N3.2	0	broad.mit.edu	37	16	5844513	5844514	+	RNA	DEL	GT	GT	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:5844513_5844514delGT	ENST00000569895.1	+	0	403																											GCCAGCgtgcgtgtgtgtgtgt	0.460													3	4	---	---	---	---					
RP11-420N3.2	0	broad.mit.edu	37	16	5869115	5869115	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:5869115delG	ENST00000569895.1	+	0	403																											accacagactgggtggcttat	0.488													2	4	---	---	---	---					
U91319.1	0	broad.mit.edu	37	16	13554710	13554710	+	RNA	DEL	C	C	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:13554710delC	ENST00000571619.1	+	0	420																											GCAAATCCTGCCCCACATTCA	0.512													2	4	---	---	---	---					
RP11-67H24.2	0	broad.mit.edu	37	16	32831197	32831197	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:32831197delT	ENST00000569859.1	+	0	373																											tattatgtgatttttacctta	0.274													2	4	---	---	---	---					
CES1P1	51716	broad.mit.edu	37	16	55808825	55808826	+	RNA	DEL	AA	AA	-	rs112369837		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:55808825_55808826delAA	ENST00000571348.1	+	0	2246_2247					NR_003276.2																						ctgtctctacaaaaaaaaaaaa	0.510													2	4	---	---	---	---					
RP11-410D17.2	0	broad.mit.edu	37	16	58866958	58866958	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:58866958delT	ENST00000500117.1	+	0	679																											aattgcccccttttttttttc	0.428													2	4	---	---	---	---					
LOC101927580	101927580	broad.mit.edu	37	16	60079515	60079515	+	RNA	DEL	A	A	-	rs34808354		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:60079515delA	ENST00000568279.1	+	0	262																											CACTTGTGCCAAAAAAAAAAA	0.328													3	3	---	---	---	---					
RP11-467L24.1	0	broad.mit.edu	37	16	64424439	64424440	+	RNA	DEL	CT	CT	-	rs66609753		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:64424439_64424440delCT	ENST00000564046.1	+	0	116																											CCATGCATAACTCAGTGAATCT	0.351													6	1	---	---	---	---					
RP11-351A20.1	0	broad.mit.edu	37	16	65667020	65667021	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:65667020_65667021insA	ENST00000563811.1	+	0	167																											GAGGTTCTATGAAAAAAAAAAA	0.332													2	4	---	---	---	---					
LINC01572	101927957	broad.mit.edu	37	16	72652669	72652670	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:72652669_72652670insA	ENST00000561611.2	-	0	113																											tgtgaacagacaaaaaaaatca	0.332													2	4	---	---	---	---					
LINC01572	101927957	broad.mit.edu	37	16	72692167	72692168	+	RNA	INS	-	-	T	rs71737505		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:72692167_72692168insT	ENST00000561611.2	-	0	113																											CTCTTTTCTGgttttttttttt	0.396													6	8	---	---	---	---					
CTD-2336H13.2	0	broad.mit.edu	37	16	76852557	76852557	+	RNA	DEL	T	T	-	rs77790186		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:76852557delT	ENST00000567777.1	+	0	138																											atctgcctccttataagactg	0.448													7	3	---	---	---	---					
CTD-2336H13.2	0	broad.mit.edu	37	16	76908676	76908677	+	RNA	INS	-	-	TG	rs33944143	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:76908676_76908677insTG	ENST00000567777.1	+	0	138																											ATGGCAATGCCtgtgtgtgtgt	0.332													4	2	---	---	---	---					
RP11-679B19.2	0	broad.mit.edu	37	16	79247686	79247687	+	RNA	INS	-	-	A	rs34595115	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:79247686_79247687insA	ENST00000569677.1	-	0	144																											cacagcaatgcaaaagatagta	0.396													6	2	---	---	---	---					
LOC102724084	102724084	broad.mit.edu	37	16	80368367	80368368	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:80368367_80368368insA	ENST00000565050.1	-	0	598				RP11-525K10.3_ENST00000568819.1_RNA|RP11-525K10.3_ENST00000568776.1_RNA																							TGTGCTGATACAAAAAGTCATT	0.356													2	4	---	---	---	---					
LOC102724084	102724084	broad.mit.edu	37	16	80470530	80470531	+	RNA	DEL	AC	AC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr16:80470530_80470531delAC	ENST00000565050.1	-	0	598				RP11-525K10.3_ENST00000568819.1_RNA|RP11-525K10.3_ENST00000568776.1_RNA																							TTTGATAGTAACACACACACAC	0.426													2	4	---	---	---	---					
RP11-47L3.1	0	broad.mit.edu	37	17	33641439	33641440	+	RNA	DEL	GT	GT	-	rs72180184		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:33641439_33641440delGT	ENST00000585387.1	+	0	43																											gagttgcccggtgtgtgcagtc	0.564													6	5	---	---	---	---					
LOC339192	339192	broad.mit.edu	37	17	43294945	43294953	+	RNA	DEL	TTCGAGATG	TTCGAGATG	-	rs141786543	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:43294945_43294953delTTCGAGATG	ENST00000586376.1	-	0	604																											ccttccttccttcgagatggagtcttgct	0.550													3	3	---	---	---	---					
RP11-763E3.1	0	broad.mit.edu	37	17	53938945	53938946	+	RNA	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:53938945_53938946insG	ENST00000571972.1	-	0	133																											TTGTGTGTGTAGGGGGGGTGGT	0.347													2	4	---	---	---	---					
RP11-60A24.3	0	broad.mit.edu	37	17	55879299	55879300	+	RNA	INS	-	-	TTTCCTCTCAG	rs58515496	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:55879299_55879300insTTTCCTCTCAG	ENST00000580960.1	-	0	254																											gttccattacctttcctctcag	0.332													3	5	---	---	---	---					
UNK	85451	broad.mit.edu	37	17	73814801	73814802	+	Frame_Shift_Ins	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr17:73814801_73814802insC	ENST00000293218.3	+	12	1678_1679	c.1678_1679insC	c.(1678-1680)cccfs	p.P560fs	UNK_ENST00000589666.1_Frame_Shift_Ins_p.P484fs			Q9C0B0	UNK_HUMAN	unkempt family zinc finger	484							nucleic acid binding|zinc ion binding			cervix(3)|endometrium(8)|kidney(2)|large_intestine(5)|lung(3)|prostate(2)|stomach(1)|upper_aerodigestive_tract(1)	25			all cancers(21;2.61e-06)|Epithelial(20;7.39e-06)|BRCA - Breast invasive adenocarcinoma(9;0.00194)|LUSC - Lung squamous cell carcinoma(166;0.154)			CCTGGCAGCTACCCCCCCTAGC	0.614													8	26	---	---	---	---					
RP11-703M24.5	0	broad.mit.edu	37	18	2818263	2818264	+	RNA	INS	-	-	A	rs59490791	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:2818263_2818264insA	ENST00000583546.1	-	0	308																											gattctgtctcaaaaaaaaaag	0.361													3	2	---	---	---	---					
RP11-419J16.1	0	broad.mit.edu	37	18	10137647	10137648	+	RNA	DEL	GA	GA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:10137647_10137648delGA	ENST00000582470.1	+	0	162																											TAGTGAAGGGGAGAGAGAGAGA	0.436													2	4	---	---	---	---					
RP11-595B24.1	0	broad.mit.edu	37	18	19618750	19618750	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:19618750delA	ENST00000584898.1	+	0	39																											gaccctgtctaaaaaaaaaaa	0.418													2	4	---	---	---	---					
KC6	641516	broad.mit.edu	37	18	39069155	39069156	+	RNA	INS	-	-	G	rs33964236	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:39069155_39069156insG	ENST00000592302.1	-	0	507					NR_002838.1																						CTGCTCAGAAACACCTGGCAGG	0.431													2	4	---	---	---	---					
LINC00907	284260	broad.mit.edu	37	18	40014142	40014142	+	RNA	DEL	A	A	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:40014142delA	ENST00000593234.1	+	0	713					NR_046456.1																						agggtaaggtaaataaagagg	0.378													2	4	---	---	---	---					
RP11-157P23.2	0	broad.mit.edu	37	18	45073761	45073762	+	RNA	INS	-	-	A	rs111636344		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:45073761_45073762insA	ENST00000565127.1	+	0	515																											gagactgtctcaaaaaaaaaaG	0.515													2	4	---	---	---	---					
LINC01538	400654	broad.mit.edu	37	18	61919062	61919067	+	RNA	DEL	ACACAC	ACACAC	-	rs68104588		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:61919062_61919067delACACAC	ENST00000588074.1	-	0	443				RP11-146N18.1_ENST00000589376.1_lincRNA	NR_033983.1																						GAAATATACAacacacacacacacac	0.335													3	4	---	---	---	---					
LOC643542	643542	broad.mit.edu	37	18	65253690	65253691	+	RNA	INS	-	-	A			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:65253690_65253691insA	ENST00000583687.1	+	0	204					NR_033921.1																						GCGGTCTGCTGAAAAAACACAT	0.386													2	4	---	---	---	---					
LINC01541	100505776	broad.mit.edu	37	18	69190310	69190311	+	RNA	DEL	TA	TA	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:69190310_69190311delTA	ENST00000568095.1	-	0	897_898					NR_038325.1																						tatttatatgtatatatatgtg	0.386													2	4	---	---	---	---					
PARD6G	84552	broad.mit.edu	37	18	77917844	77917845	+	Frame_Shift_Ins	INS	-	-	G			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr18:77917844_77917845insG	ENST00000353265.3	-	3	1137_1138	c.940_941insC	c.(940-942)gacfs	p.D314fs	AC139100.2_ENST00000585422.1_Intron|AC139100.2_ENST00000586421.1_Intron|AC139100.2_ENST00000589574.1_Intron|AC139100.2_ENST00000587254.1_Intron	NM_032510.3	NP_115899.1	Q9BYG4	PAR6G_HUMAN	par-6 family cell polarity regulator gamma	314					cell cycle|cell division|tight junction assembly	cytosol|tight junction	protein binding			haematopoietic_and_lymphoid_tissue(1)|large_intestine(4)|lung(1)|skin(1)|upper_aerodigestive_tract(1)	8		all_cancers(4;5.63e-22)|all_epithelial(4;5.86e-15)|all_lung(4;1.32e-05)|Ovarian(4;1.33e-05)|Lung NSC(4;2.77e-05)|Esophageal squamous(42;0.0157)|all_hematologic(56;0.13)|Melanoma(33;0.144)		Epithelial(2;1.48e-13)|all cancers(1;5.77e-13)|OV - Ovarian serous cystadenocarcinoma(15;2.74e-10)|BRCA - Breast invasive adenocarcinoma(31;0.00166)|STAD - Stomach adenocarcinoma(84;0.18)|Lung(128;0.23)		GCCCGGGGTCTGGGGGGGACGT	0.748													3	6	---	---	---	---					
LOC100289333	100289333	broad.mit.edu	37	19	12334418	12334419	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:12334418_12334419insT	ENST00000426044.1	+	0	127																											ATTGAAATGTATTTTTTTTGTG	0.332													2	4	---	---	---	---					
CTD-2562J15.6	0	broad.mit.edu	37	19	16405928	16405930	+	RNA	DEL	GGG	GGG	-	rs5827330	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:16405928_16405930delGGG	ENST00000588799.1	-	0	208																											gggagggggagggggaggaggag	0.527													3	6	---	---	---	---					
LOC100420587	100420587	broad.mit.edu	37	19	29007036	29007036	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:29007036delT	ENST00000592347.1	-	0	642				AC005616.2_ENST00000592931.1_lincRNA|AC005616.1_ENST00000589999.1_RNA																							taaaatcaggtttttttgttt	0.438													2	4	---	---	---	---					
LOC284395	284395	broad.mit.edu	37	19	29881765	29881766	+	RNA	INS	-	-	A	rs143827567	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:29881765_29881766insA	ENST00000582581.1	-	0	2030					NR_040029.1																						aaggaaggaggaaaggaagaaa	0.376													3	4	---	---	---	---					
LENG8-AS1	104355426	broad.mit.edu	37	19	54958798	54958799	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:54958798_54958799insT	ENST00000429922.1	-	0	504				LENG8-AS1_ENST00000416022.1_RNA																							tgcaacttttcttttttttttt	0.431													3	5	---	---	---	---					
ZIM2-AS1	101929059	broad.mit.edu	37	19	57250331	57250331	+	RNA	DEL	C	C	-	rs1029839	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr19:57250331delC	ENST00000594400.1	+	0	266				AC006115.3_ENST00000600093.1_RNA|AC006115.3_ENST00000597822.1_RNA																							accctctcttcgggtctgaat	0.443													2	4	---	---	---	---					
LOC101929312	101929312	broad.mit.edu	37	20	7343306	7343306	+	RNA	DEL	G	G	-	rs2423216	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:7343306delG	ENST00000455299.1	+	0	395																											TTCCTTTTTTGTTCCAGTACA	0.403													2	4	---	---	---	---					
LINC01270	284751	broad.mit.edu	37	20	48917691	48917692	+	RNA	INS	-	-	GGATGGAT	rs76309641	by1000genomes	TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:48917691_48917692insGGATGGAT	ENST00000371639.3	+	0	369					NR_034124.1																						atggatgggtaggatggatgga	0.450													3	5	---	---	---	---					
RP5-843L14.1	0	broad.mit.edu	37	20	55155930	55155930	+	RNA	DEL	T	T	-	rs11479233		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr20:55155930delT	ENST00000434176.1	+	0	557																											aaaggttttctttttttttgt	0.438													4	2	---	---	---	---					
TEKT4P2	100132288	broad.mit.edu	37	21	9963465	9963466	+	RNA	INS	-	-	T			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:9963465_9963466insT	ENST00000416067.1	-	0	129					NR_037872.1|NR_038327.1																						CGTGCTAAACCAGAAACCCAAA	0.426													2	4	---	---	---	---					
BAGE2	85319	broad.mit.edu	37	21	11079710	11079711	+	RNA	INS	-	-	TA	rs74711197		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:11079710_11079711insTA	ENST00000470054.1	-	0	324									B melanoma antigen family, member 2															Colorectal(6;3.44e-05)|COAD - Colon adenocarcinoma(6;0.00727)|READ - Rectum adenocarcinoma(6;0.0723)	UCEC - Uterine corpus endometrioid carcinoma (6;0.0974)|all cancers(6;2.54e-22)|Epithelial(6;4.21e-19)|OV - Ovarian serous cystadenocarcinoma(6;1.16e-09)|BRCA - Breast invasive adenocarcinoma(6;7.72e-05)|Lung(8;0.000189)|LUSC - Lung squamous cell carcinoma(6;0.00379)|GBM - Glioblastoma multiforme(6;0.00391)|Kidney(17;0.0773)|LUAD - Lung adenocarcinoma(8;0.247)		aatttttttttaaaGCAAATTC	0.406													3	5	---	---	---	---					
ANKRD30BP2	149992	broad.mit.edu	37	21	14412202	14412203	+	RNA	INS	-	-	T	rs147346900		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:14412202_14412203insT	ENST00000507941.1	+	0	95																											acagtagaaaaccagaaacacc	0.322													2	4	---	---	---	---					
CHODL-AS1	54075	broad.mit.edu	37	21	19249695	19249695	+	RNA	DEL	T	T	-	rs35401761		TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:19249695delT	ENST00000447175.1	-	0	147					NR_024354.1																						aatttatagattttttttttt	0.308													3	3	---	---	---	---					
LINC00189	193629	broad.mit.edu	37	21	30628578	30628578	+	RNA	DEL	T	T	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr21:30628578delT	ENST00000420364.1	+	0	767					NR_027072.2																						AGGTTCCTCCTTTTTTTGTAC	0.393													2	4	---	---	---	---					
LARGE	9215	broad.mit.edu	37	22	33578377	33578378	+	RNA	DEL	TG	TG	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:33578377_33578378delTG	ENST00000421232.1	-	0	150																											CCTTTCATATTGTGTGTGTGTC	0.307													2	4	---	---	---	---					
ISX-AS1	101926957	broad.mit.edu	37	22	35391188	35391188	+	RNA	DEL	G	G	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chr22:35391188delG	ENST00000448318.4	-	0	1184																											tcagaaggcaggaagcaaaag	0.473													2	4	---	---	---	---					
PTCHD1-AS	100873065	broad.mit.edu	37	X	22683392	22683393	+	RNA	INS	-	-	C			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:22683392_22683393insC	ENST00000455399.1	-	0	178																											CTAGCTCTTCTCCCCCCCAGCT	0.480													4	4	---	---	---	---					
RP1-137H15.2	0	broad.mit.edu	37	X	136639295	136639296	+	RNA	DEL	AC	AC	-			TCGA-17-Z020-01A-01W-0746-08	TCGA-17-Z020-11A-01W-0746-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	7ea20aa3-68cf-4389-9ace-99d6149d16c1	cf1e2bab-df59-4068-8c13-c894b631d4a6	g.chrX:136639295_136639296delAC	ENST00000456631.1	-	0	190																											catccttaaaacacacacacac	0.441													2	4	---	---	---	---