Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
C14orf39	317761	broad.mit.edu	37	14	60908817	60908817	+	Silent	SNP	A	A	G			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr14:60908817A>G	ENST00000321731.3	-	17	1695	c.1536T>C	c.(1534-1536)aaT>aaC	p.N512N		NM_174978.2	NP_777638.2	Q08AQ4	Q08AQ4_HUMAN	chromosome 14 open reading frame 39	512										breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(5)|lung(7)|ovary(2)|prostate(1)|skin(4)|upper_aerodigestive_tract(1)|urinary_tract(1)	30				OV - Ovarian serous cystadenocarcinoma(108;0.0448)		ATGACAGAGGATTTAGATTTC	0.274000													34	43					0	0	1	0	0
CD19	930	broad.mit.edu	37	16	28943382	28943382	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr16:28943382G>A	ENST00000538922.1	+	1	123	c.61G>A	c.(61-63)Gag>Aag	p.E21K	CD19_ENST00000567541.1_Missense_Mutation_p.E21K|CD19_ENST00000324662.3_Missense_Mutation_p.E21K	NM_001178098.1|NM_001770.5	NP_001171569.1|NP_001761.3	P15391	CD19_HUMAN	CD19 molecule	21	Ig-like C2-type 1.				cellular defense response	external side of plasma membrane|integral to plasma membrane	protein binding|receptor signaling protein activity			NS(1)|breast(3)|central_nervous_system(1)|endometrium(1)|kidney(1)|large_intestine(4)|lung(11)|ovary(2)|skin(4)|urinary_tract(1)	29						AGTCAGGCCCGAGGAACCTCT	0.597000													36	33					0	0	1	0	0
GPR124	25960	broad.mit.edu	37	8	37693223	37693223	+	Missense_Mutation	SNP	G	G	A	rs142661492	by1000genomes	TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr8:37693223G>A	ENST00000412232.2	+	13	1998	c.1985G>A	c.(1984-1986)cGc>cAc	p.R662H	GPR124_ENST00000315215.7_Intron	NM_032777.9	NP_116166.9	Q96PE1	GP124_HUMAN	G protein-coupled receptor 124	662					central nervous system development|endothelial cell migration|neuropeptide signaling pathway|regulation of angiogenesis|regulation of chemotaxis|sprouting angiogenesis	integral to membrane|plasma membrane	G-protein coupled receptor activity			central_nervous_system(1)|endometrium(5)|kidney(3)|large_intestine(4)|lung(16)|ovary(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)	37			BRCA - Breast invasive adenocarcinoma(5;2.75e-24)|LUSC - Lung squamous cell carcinoma(8;3.5e-10)			AACACCTCCCGCCCTGGAGCT	0.682000													25	44					0	0	1	0	0
HECW1	23072	broad.mit.edu	37	7	43477672	43477672	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr7:43477672G>A	ENST00000395891.1	+	9	1477	c.872G>A	c.(871-873)cGc>cAc	p.R291H	HECW1_ENST00000471043.1_3'UTR|HECW1_ENST00000453890.1_Missense_Mutation_p.R291H	NM_015052.3	NP_055867.3	Q76N89	HECW1_HUMAN	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	291	C2.				protein ubiquitination involved in ubiquitin-dependent protein catabolic process	cytoplasm|nucleus	ubiquitin-protein ligase activity			NS(2)|breast(10)|central_nervous_system(2)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(17)|lung(57)|ovary(8)|pancreas(2)|prostate(2)|skin(6)|urinary_tract(3)	125						GCCAAGAGCCGCCCCATCATC	0.473000													33	72					0	0	1	0	0
LSM14A	26065	broad.mit.edu	37	19	34685400	34685400	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:34685400G>A	ENST00000544216.3	+	2	216	c.139G>A	c.(139-141)Gaa>Aaa	p.E47K	LSM14A_ENST00000433627.5_Missense_Mutation_p.E47K|LSM14A_ENST00000540746.2_Missense_Mutation_p.E47K	NM_015578.2	NP_056393.2	Q8ND56	LS14A_HUMAN	LSM14A, SCD6 homolog A (S. cerevisiae)	47					cytoplasmic mRNA processing body assembly|multicellular organismal development|regulation of translation	cytoplasmic mRNA processing body|intracellular membrane-bounded organelle|stress granule				breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|lung(7)|skin(1)	22	Esophageal squamous(110;0.162)					CTTTGGTACAGAAGACAGACC	0.408000													88	119					0	0	1	0	0
FAM126B	285172	broad.mit.edu	37	2	201846441	201846441	+	Missense_Mutation	SNP	C	C	T	rs138872845		TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:201846441C>T	ENST00000418596.2	-	12	1332	c.1145G>A	c.(1144-1146)cGt>cAt	p.R382H	AC005037.3_ENST00000413848.1_RNA	NM_173822.3	NP_776183.1	Q8IXS8	F126B_HUMAN	family with sequence similarity 126, member B	382						intracellular				endometrium(2)|kidney(1)|large_intestine(3)|lung(5)|ovary(2)|prostate(2)|upper_aerodigestive_tract(1)	16						CTTGGCTGAACGCCCAGTTGC	0.493000													22	31					0	0	1	0	0
SLC25A4	291	broad.mit.edu	37	4	186066341	186066341	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr4:186066341G>A	ENST00000281456.5	+	2	667	c.535G>A	c.(535-537)Gtc>Atc	p.V179I	SLC25A4_ENST00000515584.1_3'UTR	NM_001151.3	NP_001142.2	P12235	ADT1_HUMAN	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4	179					energy reserve metabolic process|interspecies interaction between organisms|mitochondrial genome maintenance|negative regulation of necrotic cell death|regulation of insulin secretion|viral reproduction	integral to plasma membrane|mitochondrial inner membrane	adenine transmembrane transporter activity|protein binding			endometrium(2)|kidney(1)|large_intestine(3)|lung(2)|ovary(1)|prostate(1)	10		all_lung(41;1.19e-13)|Lung NSC(41;3.16e-13)|Hepatocellular(41;0.00826)|Colorectal(36;0.00872)|Renal(120;0.00988)|Prostate(90;0.0235)|all_hematologic(60;0.0592)|all_neural(102;0.243)		OV - Ovarian serous cystadenocarcinoma(60;4.48e-44)|Epithelial(43;2.1e-41)|all cancers(43;1.37e-36)|Colorectal(24;4.79e-05)|BRCA - Breast invasive adenocarcinoma(30;7.72e-05)|GBM - Glioblastoma multiforme(59;0.000274)|COAD - Colon adenocarcinoma(29;0.000362)|STAD - Stomach adenocarcinoma(60;0.000756)|LUSC - Lung squamous cell carcinoma(40;0.00902)|READ - Rectum adenocarcinoma(43;0.155)	Adenosine triphosphate(DB00171)|Clodronate(DB00720)	GGGTTTCAACGTCTCTGTCCA	0.562000													12	15					0	0	1	0	0
NDOR1	27158	broad.mit.edu	37	9	140110110	140110110	+	Splice_Site	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr9:140110110G>A	ENST00000371521.4	+	11	1371		c.e11-1		NDOR1_ENST00000458322.2_Splice_Site|NDOR1_ENST00000344894.5_Splice_Site|NDOR1_ENST00000427047.2_Splice_Site	NM_001144026.1	NP_001137498.1	Q9UHB4	NDOR1_HUMAN	NADPH dependent diflavin oxidoreductase 1						cell death	cytosol|intermediate filament cytoskeleton|nucleus|perinuclear region of cytoplasm	flavin adenine dinucleotide binding|FMN binding|iron ion binding|NADP binding|oxidoreductase activity|protein binding			breast(1)|endometrium(5)|large_intestine(1)|lung(5)|prostate(1)|skin(1)|urinary_tract(1)	15	all_cancers(76;0.0926)		STAD - Stomach adenocarcinoma(284;0.0698)	OV - Ovarian serous cystadenocarcinoma(145;6.37e-05)|Epithelial(140;0.00057)		TCCTGCAATAGGACCTGTCCG	0.607000													20	15					0	0	1	0	0
ATG4D	84971	broad.mit.edu	37	19	10659651	10659651	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:10659651C>T	ENST00000309469.4	+	6	1080	c.907C>T	c.(907-909)Ctg>Ttg	p.L303L	ATG4D_ENST00000540862.1_Intron	NM_032885.4	NP_116274.3	Q86TL0	ATG4D_HUMAN	autophagy related 4D, cysteine peptidase	303					autophagy|protein transport	cytoplasm	cysteine-type endopeptidase activity			NS(1)|endometrium(1)|kidney(1)|large_intestine(5)|lung(6)|prostate(1)|upper_aerodigestive_tract(1)|urinary_tract(3)	19			Epithelial(33;9.2e-06)|all cancers(31;3.9e-05)			TGTGGTCATCCTGGTGCCCGT	0.632000													25	23					0	0	1	0	0
BMS1	9790	broad.mit.edu	37	10	43292066	43292066	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr10:43292066C>T	ENST00000374518.4	+	10	1437	c.1374C>T	c.(1372-1374)aaC>aaT	p.N458N		NM_014753.3	NP_055568.3	Q14692	BMS1_HUMAN	BMS1 ribosome biogenesis factor	458					ribosome assembly	nucleolus	ATP binding|GTP binding|GTPase activity			NS(1)|breast(3)|endometrium(5)|haematopoietic_and_lymphoid_tissue(1)|kidney(6)|large_intestine(15)|lung(23)|ovary(2)|prostate(2)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	62						GGTTGGAAAACGGCTCTAGTG	0.443000													16	8					0	0	1	0	0
LSM14A	26065	broad.mit.edu	37	19	34685448	34685448	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:34685448G>A	ENST00000544216.3	+	2	264	c.187G>A	c.(187-189)Gaa>Aaa	p.E63K	LSM14A_ENST00000433627.5_Missense_Mutation_p.E63K|LSM14A_ENST00000540746.2_Missense_Mutation_p.E63K	NM_015578.2	NP_056393.2	Q8ND56	LS14A_HUMAN	LSM14A, SCD6 homolog A (S. cerevisiae)	63					cytoplasmic mRNA processing body assembly|multicellular organismal development|regulation of translation	cytoplasmic mRNA processing body|intracellular membrane-bounded organelle|stress granule				breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|lung(7)|skin(1)	22	Esophageal squamous(110;0.162)					TGAAGTCTTTGAATACATTAT	0.433000													76	124					0	0	1	0	0
SRRM3	222183	broad.mit.edu	37	7	75894112	75894112	+	Missense_Mutation	SNP	A	A	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr7:75894112A>T	ENST00000388802.4	+	9	913	c.704A>T	c.(703-705)gAg>gTg	p.E235V	SRRM3_ENST00000326382.8_Missense_Mutation_p.E235V					serine/arginine repetitive matrix 3											NS(1)|cervix(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(1)|lung(3)|pancreas(1)	8						AAAAGAAAAGAGAAGAACAAA	0.567000													13	21					0	0	1	0	0
TTN	7273	broad.mit.edu	37	2	179485844	179485844	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:179485844G>A	ENST00000589042.1	-	246	45825	c.45601C>T	c.(45601-45603)Cac>Tac	p.H15201Y	TTN_ENST00000342175.6_Missense_Mutation_p.H6328Y|TTN_ENST00000460472.2_Missense_Mutation_p.H6136Y|TTN_ENST00000342992.6_Missense_Mutation_p.H12633Y|TTN_ENST00000359218.5_Missense_Mutation_p.H6261Y|TTN-AS1_ENST00000589487.1_RNA|TTN-AS1_ENST00000592630.1_RNA|TTN-AS1_ENST00000589907.1_RNA|TTN_ENST00000591111.1_Missense_Mutation_p.H13560Y|TTN-AS1_ENST00000590807.1_RNA|TTN-AS1_ENST00000589830.1_RNA|TTN-AS1_ENST00000585451.1_RNA	NM_001267550.1	NP_001254479.1	Q8WZ42	TITIN_HUMAN	titin	13560	Fibronectin type-III 10.						ATP binding|nucleic acid binding|protein serine/threonine kinase activity|protein tyrosine kinase activity			NS(24)|autonomic_ganglia(1)|breast(64)|central_nervous_system(14)|cervix(14)|endometrium(96)|haematopoietic_and_lymphoid_tissue(16)|kidney(91)|large_intestine(303)|liver(1)|lung(595)|ovary(58)|pancreas(17)|prostate(38)|skin(60)|stomach(29)|upper_aerodigestive_tract(1)|urinary_tract(26)	1448			OV - Ovarian serous cystadenocarcinoma(117;0.023)|Epithelial(96;0.0454)|all cancers(119;0.134)			ACTGTCAAGTGAGCTGCTGCT	0.383000													18	16					0	0	1	0	0
AHR	196	broad.mit.edu	37	7	17379426	17379426	+	Silent	SNP	C	C	T	rs139422560	byFrequency	TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr7:17379426C>T	ENST00000242057.4	+	10	2620	c.1977C>T	c.(1975-1977)ttC>ttT	p.F659F		NM_001621.4	NP_001612.1	P35869	AHR_HUMAN	aryl hydrocarbon receptor	659					apoptosis|blood vessel development|cell cycle|regulation of B cell proliferation|response to stress|transcription from RNA polymerase II promoter|xenobiotic metabolic process	cytosolic aryl hydrocarbon receptor complex|transcription factor complex	Hsp90 protein binding|ligand-dependent nuclear receptor activity|protein heterodimerization activity|sequence-specific DNA binding transcription factor activity|transcription factor binding|transcription regulatory region DNA binding			NS(1)|central_nervous_system(1)|endometrium(3)|kidney(4)|large_intestine(8)|lung(11)|ovary(1)|pancreas(1)|urinary_tract(3)	33	Lung NSC(10;0.0392)|all_lung(11;0.0754)					CTAACCAATTCGTGCCTTTCA	0.408000													45	102					0	0	1	0	0
MPDZ	8777	broad.mit.edu	37	9	13108990	13108990	+	Missense_Mutation	SNP	C	C	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr9:13108990C>A	ENST00000319217.7	-	46	6258	c.6011G>T	c.(6010-6012)gGa>gTa	p.G2004V	MPDZ_ENST00000541093.1_Missense_Mutation_p.G238V|MPDZ_ENST00000381022.2_Missense_Mutation_p.G1975V|MPDZ_ENST00000546205.1_Missense_Mutation_p.G2018V|MPDZ_ENST00000447879.1_Missense_Mutation_p.G1971V|MPDZ_ENST00000541718.1_Missense_Mutation_p.G1975V|MPDZ_ENST00000381015.4_Missense_Mutation_p.G2004V|MPDZ_ENST00000538841.1_Missense_Mutation_p.G863V|MPDZ_ENST00000536827.1_Missense_Mutation_p.G1942V	NM_001261406.1	NP_001248335.1	O75970	MPDZ_HUMAN	multiple PDZ domain protein	2004	PDZ 13.				interspecies interaction between organisms	apical plasma membrane|dendrite|postsynaptic density|postsynaptic membrane|synaptosome|tight junction	protein C-terminus binding			NS(1)|breast(2)|central_nervous_system(1)|endometrium(7)|haematopoietic_and_lymphoid_tissue(4)|kidney(2)|large_intestine(14)|lung(15)|ovary(5)|prostate(7)|stomach(1)|urinary_tract(2)	61				GBM - Glioblastoma multiforme(50;2.03e-06)		GCTGCCATATCCTCCAACTAT	0.413000													7	6					8.12818e-05	8.12818e-05	1	1	0
TBCE	6905	broad.mit.edu	37	1	235543460	235543460	+	Silent	SNP	G	G	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr1:235543460G>C	ENST00000543662.1	+	2	202	c.96G>C	c.(94-96)gtG>gtC	p.V32V	TBCE_ENST00000366601.3_Silent_p.V32V|TBCE_ENST00000406207.1_Silent_p.V32V|TBCE_ENST00000472011.1_3'UTR			Q15813	TBCE_HUMAN	tubulin folding cofactor E	32	CAP-Gly.				'de novo' posttranslational protein folding|post-chaperonin tubulin folding pathway	cytoplasm|microtubule|nucleus|plasma membrane	chaperone binding			NS(1)|endometrium(2)|large_intestine(3)|lung(6)|prostate(1)|skin(1)	14	Ovarian(103;0.0634)|Breast(184;0.23)	all_cancers(173;0.00192)|Prostate(94;0.0294)|all_epithelial(177;0.155)|Lung SC(1967;0.238)	OV - Ovarian serous cystadenocarcinoma(106;2.56e-05)			TCCCTCCCGTGGCAGGTAAGC	0.443000													17	28					0	0	1	0	0
HN1	51155	broad.mit.edu	37	17	73144759	73144759	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr17:73144759G>A	ENST00000409753.3	-	2	349	c.64C>T	c.(64-66)Cgg>Tgg	p.R22W	HN1_ENST00000482348.1_5'UTR|HN1_ENST00000581874.1_Missense_Mutation_p.R22W|HN1_ENST00000481647.1_5'UTR|HN1_ENST00000476258.1_5'UTR|HN1_ENST00000405458.3_5'UTR|HN1_ENST00000470924.1_5'UTR|HN1_ENST00000392566.2_5'UTR|HN1_ENST00000356033.4_Missense_Mutation_p.R22W|HN1_ENST00000465454.1_5'UTR	NM_016185.2	NP_057269.1	Q9UK76	HN1_HUMAN	hematological and neurological expressed 1	22						nucleus			HN1/USH1G(2)	breast(1)	1	all_lung(278;0.14)|Lung NSC(278;0.168)					CCTGGAGGCCGCAAAACTCTG	0.393000													3	51					0	0	1	0	0
STAT1	6772	broad.mit.edu	37	2	191865866	191865866	+	Silent	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:191865866G>A	ENST00000361099.3	-	6	783	c.396C>T	c.(394-396)agC>agT	p.S132S	STAT1_ENST00000540176.1_Silent_p.S132S|STAT1_ENST00000409465.1_Silent_p.S132S|STAT1_ENST00000392322.3_Silent_p.S132S|STAT1_ENST00000392323.2_Silent_p.S134S	NM_007315.3	NP_009330.1	P42224	STAT1_HUMAN	signal transducer and activator of transcription 1, 91kDa	132					activation of caspase activity|I-kappaB kinase/NF-kappaB cascade|interferon-gamma-mediated signaling pathway|interspecies interaction between organisms|regulation of interferon-gamma-mediated signaling pathway|regulation of type I interferon-mediated signaling pathway|response to virus|type I interferon-mediated signaling pathway|tyrosine phosphorylation of STAT protein	cytosol|nucleolus|nucleoplasm	calcium ion binding|protein binding|RNA polymerase II core promoter sequence-specific DNA binding|RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity|signal transducer activity			autonomic_ganglia(1)|breast(3)|central_nervous_system(2)|cervix(2)|endometrium(5)|kidney(2)|large_intestine(6)|lung(13)|ovary(2)|upper_aerodigestive_tract(2)|urinary_tract(1)	39			OV - Ovarian serous cystadenocarcinoma(117;0.00434)|Epithelial(96;0.0555)|all cancers(119;0.141)		Fludarabine(DB01073)	ACATCACTGTGCTCTGAATAT	0.413000													25	34					0	0	1	0	0
HAO1	54363	broad.mit.edu	37	20	7915166	7915166	+	Missense_Mutation	SNP	A	A	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr20:7915166A>T	ENST00000378789.3	-	2	305	c.254T>A	c.(253-255)aTg>aAg	p.M85K		NM_017545.2	NP_060015.1	Q9UJM8	HAOX1_HUMAN	hydroxyacid oxidase (glycolate oxidase) 1	85	FMN hydroxy acid dehydrogenase.				cellular nitrogen compound metabolic process|fatty acid alpha-oxidation|glycolate catabolic process|glyoxylate metabolic process	peroxisomal matrix	FMN binding|glycolate oxidase activity|glyoxylate oxidase activity			breast(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(7)|lung(19)|ovary(3)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	36						CACATGAGCCATGCGCTGCAT	0.532000													23	26					0	0	1	0	0
UNCX	340260	broad.mit.edu	37	7	1275471	1275471	+	Missense_Mutation	SNP	T	T	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr7:1275471T>C	ENST00000316333.8	+	3	565	c.454T>C	c.(454-456)Tgg>Cgg	p.W152R		NM_001080461.1	NP_001073930.1	A6NJT0	UNC4_HUMAN	UNC homeobox	152					cell differentiation	nucleus	sequence-specific DNA binding|sequence-specific DNA binding transcription factor activity			lung(2)|skin(1)|upper_aerodigestive_tract(1)	4		Ovarian(82;0.11)		UCEC - Uterine corpus endometrioid carcinoma (27;0.0178)|OV - Ovarian serous cystadenocarcinoma(56;1.74e-15)		GCTCTAGGTCTGGTTCCAAAA	0.697000													8	14					0	0	1	0	0
OBSCN	84033	broad.mit.edu	37	1	228564858	228564858	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr1:228564858C>T	ENST00000570156.2	+	112	26090	c.26016C>T	c.(26014-26016)cgC>cgT	p.R8672R	OBSCN_ENST00000366707.4_Silent_p.R5349R|OBSCN_ENST00000422127.1_Silent_p.R7715R	NM_001271223.2	NP_001258152.2	Q5VST9	OBSCN_HUMAN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	7715					apoptosis|cell differentiation|induction of apoptosis by extracellular signals|multicellular organismal development|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction	cytosol|M band|Z disc	ATP binding|metal ion binding|protein binding|protein serine/threonine kinase activity|protein tyrosine kinase activity|Rho guanyl-nucleotide exchange factor activity|structural constituent of muscle|titin binding			NS(2)|breast(7)|central_nervous_system(5)|cervix(2)|endometrium(30)|haematopoietic_and_lymphoid_tissue(1)|kidney(4)|large_intestine(37)|lung(89)|ovary(8)|pancreas(3)|prostate(13)|skin(6)|stomach(11)|upper_aerodigestive_tract(2)|urinary_tract(3)	223		Prostate(94;0.0405)				CAGTGCTGCGCGAATACGAGG	0.677000													6	10					0	0	1	0	0
IGKV2D-29	0	broad.mit.edu	37	2	89986862	89986862	+	RNA	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:89986862G>A	ENST00000491977.1	+	0	173																											TCTAGTCAGAGCCTCCTGCAT	0.522000													28	34					0	0	1	0	0
MAPK11	5600	broad.mit.edu	37	22	50705842	50705842	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr22:50705842C>T	ENST00000330651.6	-	4	475	c.375G>A	c.(373-375)gaG>gaA	p.E125E	MAPK11_ENST00000449719.2_Silent_p.E17E|MAPK11_ENST00000495277.1_5'UTR	NM_002751.5	NP_002742.3	Q15759	MK11_HUMAN	mitogen-activated protein kinase 11	125	Protein kinase.				activation of MAPK activity|innate immune response|mRNA metabolic process|muscle cell differentiation|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|nerve growth factor receptor signaling pathway|positive regulation of muscle cell differentiation|Ras protein signal transduction|regulation of sequence-specific DNA binding transcription factor activity|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	cytosol|nucleoplasm	ATP binding|MAP kinase activity|protein binding			breast(1)|central_nervous_system(1)|lung(4)	6		all_cancers(38;5.78e-13)|all_epithelial(38;1.71e-11)|all_lung(38;3.89e-05)|Breast(42;0.000523)|Lung NSC(38;0.000992)|Ovarian(80;0.0221)|Hepatocellular(38;0.0691)|Lung SC(80;0.113)		BRCA - Breast invasive adenocarcinoma(115;0.205)|LUAD - Lung adenocarcinoma(64;0.247)		ATTGAACGTGCTCGTCGCTCA	0.701000													10	2					0	0	1	0	0
NLRP2	55655	broad.mit.edu	37	19	55494752	55494752	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:55494752C>T	ENST00000543010.1	+	6	1829	c.1686C>T	c.(1684-1686)aaC>aaT	p.N562N	NLRP2_ENST00000538819.1_Silent_p.N538N|NLRP2_ENST00000537859.1_Silent_p.N540N|NLRP2_ENST00000339757.7_Silent_p.N540N|NLRP2_ENST00000427260.2_Silent_p.N539N|NLRP2_ENST00000391721.4_Silent_p.N538N|NLRP2_ENST00000263437.6_Silent_p.N559N|NLRP2_ENST00000448584.2_Silent_p.N562N	NM_001174081.1	NP_001167552.1	Q9NX02	NALP2_HUMAN	NLR family, pyrin domain containing 2	562					apoptosis|positive regulation of caspase activity|positive regulation of interleukin-1 beta secretion	cytoplasm	ATP binding|Pyrin domain binding			large_intestine(4)|liver(1)|ovary(1)|skin(2)|upper_aerodigestive_tract(3)	11			BRCA - Breast invasive adenocarcinoma(297;0.163)	GBM - Glioblastoma multiforme(193;0.028)		GCCTCGCTAACGAGAAGAGAG	0.542000													20	49					0	0	1	0	0
ETAA1	54465	broad.mit.edu	37	2	67631743	67631743	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:67631743C>T	ENST00000272342.5	+	5	2059	c.1929C>T	c.(1927-1929)tcC>tcT	p.S643S	ETAA1_ENST00000462772.1_Intron	NM_019002.3	NP_061875.2	Q9NY74	ETAA1_HUMAN	Ewing tumor-associated antigen 1	643						cytoplasm|nucleus				autonomic_ganglia(1)|breast(1)|central_nervous_system(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(10)|lung(9)|ovary(3)|prostate(1)|stomach(3)|urinary_tract(1)	33						ATAATAATTCCGAACATGGAG	0.358000													68	99					0	0	1	0	0
SERPINB13	5275	broad.mit.edu	37	18	61264400	61264400	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr18:61264400G>A	ENST00000344731.5	+	8	1081	c.979G>A	c.(979-981)Gcc>Acc	p.A327T	SERPINB13_ENST00000269489.5_Missense_Mutation_p.A275T	NM_012397.3	NP_036529.1	Q9UIV8	SPB13_HUMAN	serpin peptidase inhibitor, clade B (ovalbumin), member 13	327					regulation of proteolysis|response to UV	cytoplasm|extracellular region	serine-type endopeptidase inhibitor activity			breast(1)|endometrium(1)|kidney(1)|large_intestine(3)|lung(15)|ovary(1)|prostate(2)|urinary_tract(1)	25						CGGGTTGTACGCCCAGAAGTT	0.592000													23	30					0	0	1	0	0
SLC27A2	11001	broad.mit.edu	37	15	50497454	50497454	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr15:50497454G>A	ENST00000267842.5	+	4	1098	c.866G>A	c.(865-867)cGg>cAg	p.R289Q	SLC27A2_ENST00000380902.4_Missense_Mutation_p.R236Q|SLC27A2_ENST00000544960.1_Missense_Mutation_p.R54Q	NM_003645.3	NP_003636.2	O14975	S27A2_HUMAN	solute carrier family 27 (fatty acid transporter), member 2	289					bile acid biosynthetic process|fatty acid alpha-oxidation	endoplasmic reticulum membrane|integral to membrane|peroxisomal matrix|peroxisomal membrane	ATP binding|long-chain fatty acid-CoA ligase activity|phytanate-CoA ligase activity|pristanate-CoA ligase activity			NS(1)|breast(2)|endometrium(3)|large_intestine(4)|lung(9)|ovary(1)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	25		all_lung(180;0.00177)		all cancers(107;1.16e-06)|GBM - Glioblastoma multiforme(94;0.000113)		CTTGCCTTGCGGACTAAATTT	0.398000													44	66					0	0	1	0	0
PCDHA3	0	broad.mit.edu	37	5	140182557	140182557	+	Missense_Mutation	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr5:140182557C>T	ENST00000522353.2	+	1	1775	c.1775C>T	c.(1774-1776)gCg>gTg	p.A592V	PCDHA2_ENST00000520672.2_Intron|PCDHA2_ENST00000526136.1_Intron|PCDHA3_ENST00000532566.2_Missense_Mutation_p.A592V|PCDHA1_ENST00000504120.2_Intron|PCDHA1_ENST00000394633.3_Intron	NM_018906.2	NP_061729.1														NS(1)|breast(1)|endometrium(16)|kidney(3)|large_intestine(19)|lung(36)|ovary(7)|prostate(8)|skin(3)|stomach(1)	95			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			CACGTGGTAGCGAAGGTGCGC	0.682000													42	42					0	0	1	0	0
RGPD4	285190	broad.mit.edu	37	2	108455411	108455411	+	Silent	SNP	T	T	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:108455411T>C	ENST00000408999.3	+	4	473	c.396T>C	c.(394-396)taT>taC	p.Y132Y	RGPD4_ENST00000354986.4_Silent_p.Y132Y	NM_182588.2	NP_872394.2	Q7Z3J3	RGPD4_HUMAN	RANBP2-like and GRIP domain containing 4	132					intracellular transport		binding			breast(1)|endometrium(7)|kidney(4)|lung(23)|pancreas(1)|prostate(1)|skin(3)|urinary_tract(3)	43						CTGCAATTTATAAACTAAAGG	0.318000													69	67					0	0	1	0	0
LSM14A	26065	broad.mit.edu	37	19	34685496	34685496	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:34685496G>A	ENST00000544216.3	+	2	312	c.235G>A	c.(235-237)Gag>Aag	p.E79K	LSM14A_ENST00000433627.5_Missense_Mutation_p.E79K|LSM14A_ENST00000540746.2_Missense_Mutation_p.E79K	NM_015578.2	NP_056393.2	Q8ND56	LS14A_HUMAN	LSM14A, SCD6 homolog A (S. cerevisiae)	79					cytoplasmic mRNA processing body assembly|multicellular organismal development|regulation of translation	cytoplasmic mRNA processing body|intracellular membrane-bounded organelle|stress granule				breast(1)|endometrium(4)|kidney(1)|large_intestine(8)|lung(7)|skin(1)	22	Esophageal squamous(110;0.162)					TACTGTTTGTGAGCCACCAAA	0.438000													82	108					0	0	1	0	0
CDRT4	284040	broad.mit.edu	37	17	15341350	15341350	+	Nonsense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr17:15341350G>A	ENST00000312177.6	-	4	476	c.196C>T	c.(196-198)Cag>Tag	p.Q66*	TVP23C_ENST00000519970.1_3'UTR|TVP23C-CDRT4_ENST00000522212.2_3'UTR|CDRT4_ENST00000519354.1_5'UTR	NM_001204477.1	NP_001191406.1	Q8N9R6	CDRT4_HUMAN	CMT1A duplicated region transcript 4	66										endometrium(3)|skin(1)	4				UCEC - Uterine corpus endometrioid carcinoma (92;0.0874)		GGTTTATTCTGCCTTGATGCC	0.483000													39	38					0	0	1	0	0
RAPSN	5913	broad.mit.edu	37	11	47469622	47469622	+	Silent	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr11:47469622G>A	ENST00000298854.2	-	2	486	c.273C>T	c.(271-273)cgC>cgT	p.R91R	RAPSN_ENST00000524487.1_Silent_p.R91R|RAPSN_ENST00000352508.3_Silent_p.R91R|RAPSN_ENST00000529341.1_Silent_p.R91R	NM_005055.4	NP_005046.2	Q13702	RAPSN_HUMAN	receptor-associated protein of the synapse	91					synaptic transmission, cholinergic	cell junction|cytoskeleton|postsynaptic membrane	acetylcholine receptor binding|zinc ion binding			endometrium(1)|large_intestine(3)|lung(6)|ovary(2)	12						TCTCGTTGCTGCGTGCCAGGT	0.632000													9	23					0	0	1	0	0
ASB10	136371	broad.mit.edu	37	7	150883516	150883516	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr7:150883516G>A	ENST00000422024.1	-	2	807	c.682C>T	c.(682-684)Cgc>Tgc	p.R228C	ASB10_ENST00000434669.1_Missense_Mutation_p.R228C|ASB10_ENST00000377867.3_Missense_Mutation_p.R168C|ASB10_ENST00000420175.2_Missense_Mutation_p.R183C|ASB10_ENST00000275838.1_Missense_Mutation_p.R183C	NM_001142459.1	NP_001135931.2	Q8WXI3	ASB10_HUMAN	ankyrin repeat and SOCS box containing 10	183					intracellular signal transduction					NS(1)|endometrium(2)|lung(7)|skin(2)	12			OV - Ovarian serous cystadenocarcinoma(82;0.00448)	UCEC - Uterine corpus endometrioid carcinoma (81;0.168)		TGCAGGGGGCGTTTCCCATCC	0.642000													4	5					0	0	1	0	0
HKDC1	80201	broad.mit.edu	37	10	70986987	70986987	+	Missense_Mutation	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr10:70986987C>T	ENST00000354624.5	+	2	221	c.88C>T	c.(88-90)Cgg>Tgg	p.R30W	RP11-227H15.4_ENST00000450995.1_RNA|HKDC1_ENST00000395086.2_Missense_Mutation_p.R30W	NM_025130.3	NP_079406.3	Q2TB90	HKDC1_HUMAN	hexokinase domain containing 1	30					glycolysis	mitochondrion|nucleus	ATP binding|hexokinase activity			breast(1)|endometrium(3)|haematopoietic_and_lymphoid_tissue(1)|kidney(1)|large_intestine(9)|lung(11)|ovary(5)|prostate(1)|skin(1)|upper_aerodigestive_tract(1)	34						GTATCACATGCGGCTCTCCGA	0.612000													4	35					0	0	1	0	0
GOLGA8DP	0	broad.mit.edu	37	15	22709637	22709637	+	RNA	SNP	T	T	G	rs140467724	by1000genomes	TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr15:22709637T>G	ENST00000314246.8	-	0	1147																											CCCATCTGGTTTTTGAGTTTG	0.547000													4	354					0	0	1	0	0
EDC4	23644	broad.mit.edu	37	16	67913854	67913854	+	Silent	SNP	T	T	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr16:67913854T>C	ENST00000358933.5	+	16	2162	c.1923T>C	c.(1921-1923)gcT>gcC	p.A641A		NM_014329.4	NP_055144.3	Q6P2E9	EDC4_HUMAN	enhancer of mRNA decapping 4	641	Ser-rich.				exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	cytoplasmic mRNA processing body|cytosol|nucleus	protein binding			breast(3)|central_nervous_system(2)|cervix(1)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(3)|large_intestine(4)|lung(8)|ovary(4)|skin(2)|upper_aerodigestive_tract(4)|urinary_tract(2)	41		Ovarian(137;0.0563)		OV - Ovarian serous cystadenocarcinoma(108;0.0042)|Epithelial(162;0.0185)|all cancers(182;0.121)		GCACCTCAGCTGTGGACCCCT	0.612000													6	9					0	0	1	0	0
WWP2	11060	broad.mit.edu	37	16	69971126	69971126	+	Silent	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr16:69971126C>T	ENST00000359154.2	+	20	2324	c.2223C>T	c.(2221-2223)gaC>gaT	p.D741D	WWP2_ENST00000568684.1_Silent_p.D302D|WWP2_ENST00000544162.1_3'UTR|WWP2_ENST00000448661.1_Silent_p.D741D|WWP2_ENST00000542271.1_Silent_p.D625D|WWP2_ENST00000356003.2_Silent_p.D741D	NM_001270454.1|NM_007014.4	NP_001257383.1|NP_008945.2	O00308	WWP2_HUMAN	WW domain containing E3 ubiquitin protein ligase 2	741	HECT.				entry of virus into host cell|negative regulation of protein transport|negative regulation of sequence-specific DNA binding transcription factor activity|negative regulation of transcription from RNA polymerase II promoter|negative regulation of transporter activity|proteasomal ubiquitin-dependent protein catabolic process|protein K63-linked ubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process	cytoplasm|nucleus|ubiquitin ligase complex	RNA polymerase II transcription factor binding|ubiquitin-protein ligase activity			breast(4)|endometrium(2)|kidney(2)|large_intestine(11)|lung(13)|ovary(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(2)|urinary_tract(1)	42						GCTACTTTGACGAGAAAGAGC	0.602000													13	12					0	0	1	0	0
TNFSF14	0	broad.mit.edu	37	19	6664992	6664992	+	Missense_Mutation	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:6664992C>T	ENST00000326176.9	-	5	941	c.560G>A	c.(559-561)cGc>cAc	p.R187H	TNFSF14_ENST00000599359.1_Missense_Mutation_p.R223H|TNFSF14_ENST00000245912.3_Missense_Mutation_p.R187H	NM_003807.3|NM_172014.2	NP_003798.2|NP_742011.2	O43557	TNF14_HUMAN	tumor necrosis factor (ligand) superfamily, member 14	223					cellular response to mechanical stimulus|immune response|induction of apoptosis|release of cytoplasmic sequestered NF-kappaB|T cell homeostasis|T cell proliferation	cytoplasm|extracellular space|integral to membrane|plasma membrane	caspase inhibitor activity|cytokine activity|tumor necrosis factor receptor binding			breast(1)|kidney(2)|large_intestine(4)|liver(1)|lung(4)|ovary(1)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	18						TCGAACCAGGCGTTCATCCAG	0.607000													41	73					0	0	1	0	0
SCN9A	6335	broad.mit.edu	37	2	167055493	167055493	+	Missense_Mutation	SNP	G	G	A			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:167055493G>A	ENST00000375387.4	-	27	5999	c.5659C>T	c.(5659-5661)Cgg>Tgg	p.R1887W	AC010127.3_ENST00000447809.2_RNA|SCN9A_ENST00000409435.1_Missense_Mutation_p.R1886W|SCN9A_ENST00000409672.1_Missense_Mutation_p.R1875W|SCN9A_ENST00000303354.6_Missense_Mutation_p.R1887W			Q15858	SCN9A_HUMAN	sodium channel, voltage-gated, type IX, alpha subunit	1886						voltage-gated sodium channel complex	voltage-gated sodium channel activity	p.R1875W(1)		NS(1)|breast(5)|central_nervous_system(6)|endometrium(6)|kidney(3)|large_intestine(27)|lung(38)|ovary(6)|prostate(8)|skin(4)|upper_aerodigestive_tract(2)|urinary_tract(2)	108					Lamotrigine(DB00555)|Lidocaine(DB00281)	TCTTGTTTCCGTTTTAGTGTG	0.403000													48	78					0	0	1	0	0
PCMTD1	115294	broad.mit.edu	37	8	52733212	52733212	+	Missense_Mutation	SNP	A	A	G			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr8:52733212A>G	ENST00000360540.5	-	7	1179	c.773T>C	c.(772-774)tTc>tCc	p.F258S	PCMTD1_ENST00000522514.1_Missense_Mutation_p.F258S|PCMTD1_ENST00000519559.1_5'UTR|PCMTD1_ENST00000544451.1_Missense_Mutation_p.F182S	NM_052937.2	NP_443169.2	Q96MG8	PCMD1_HUMAN	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	258						cytoplasm	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity			NS(2)|endometrium(1)|kidney(3)|large_intestine(3)|lung(17)|prostate(2)|skin(8)|soft_tissue(1)	37		Lung NSC(129;0.0795)|all_lung(136;0.144)				ATCATTTATGAAATTTCTAAG	0.393000													5	96					0	0	1	0	0
PPFIA2	8499	broad.mit.edu	37	12	81746923	81746923	+	Silent	SNP	A	A	G			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr12:81746923A>G	ENST00000550584.2	-	16	2264	c.1969T>C	c.(1969-1971)Ttg>Ctg	p.L657L	PPFIA2_ENST00000541017.1_5'UTR|PPFIA2_ENST00000541570.2_Silent_p.L224L|PPFIA2_ENST00000407050.4_Silent_p.L583L|PPFIA2_ENST00000550359.2_Silent_p.L504L|PPFIA2_ENST00000552948.1_Silent_p.L657L|PPFIA2_ENST00000548586.1_Silent_p.L657L|PPFIA2_ENST00000443686.3_Silent_p.L558L|PPFIA2_ENST00000333447.7_Silent_p.L639L|PPFIA2_ENST00000545296.2_Intron|PPFIA2_ENST00000549396.1_Silent_p.L657L|PPFIA2_ENST00000549325.1_Silent_p.L639L	NM_001220473.1	NP_001207402.1	B7Z663	B7Z663_HUMAN	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	583										NS(1)|autonomic_ganglia(1)|central_nervous_system(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(3)|large_intestine(15)|lung(37)|ovary(3)|pancreas(1)|prostate(2)|skin(2)|upper_aerodigestive_tract(5)	85						ATGGCATCCAATTGTTCCTGA	0.368000													19	28					0	0	1	0	0
CDH22	64405	broad.mit.edu	37	20	44839196	44839196	+	Missense_Mutation	SNP	G	G	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr20:44839196G>C	ENST00000372262.3	-	6	1436	c.1036C>G	c.(1036-1038)Ctg>Gtg	p.L346V	CDH22_ENST00000474438.1_5'UTR|CDH22_ENST00000537909.1_Missense_Mutation_p.L346V	NM_021248.1	NP_067071.1	Q9UJ99	CAD22_HUMAN	cadherin 22, type 2	346	Cadherin 3.				homophilic cell adhesion	integral to membrane|plasma membrane	calcium ion binding			endometrium(3)|kidney(1)|large_intestine(9)|lung(16)|ovary(4)|pancreas(1)|prostate(3)|skin(4)|urinary_tract(3)	44		Myeloproliferative disorder(115;0.0122)				TCGAAGTCCAGGCGCTGCGGG	0.682000													12	16					0	0	1	0	0
UGT2A1	10941	broad.mit.edu	37	4	70465099	70465099	+	Silent	SNP	C	C	T	rs141938191		TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr4:70465099C>T	ENST00000503640.1	-	2	784	c.729G>A	c.(727-729)acG>acA	p.T243T	UGT2A1_ENST00000512704.1_Silent_p.T243T|UGT2A2_ENST00000457664.2_Silent_p.T252T|UGT2A1_ENST00000502343.1_5'UTR|UGT2A1_ENST00000514019.1_Silent_p.T453T|UGT2A1_ENST00000286604.4_Silent_p.T287T	NM_006798.3	NP_006789.2	Q9Y4X1	UD2A1_HUMAN	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus	243					detection of chemical stimulus|sensory perception of smell	integral to membrane	glucuronosyltransferase activity			NS(1)|central_nervous_system(1)|endometrium(1)|kidney(3)|large_intestine(8)|lung(11)|ovary(2)|prostate(1)|skin(2)	30						TCTCACATAACGTAGTGGGTC	0.368000													27	37					0	0	1	0	0
SNED1	25992	broad.mit.edu	37	2	242002232	242002232	+	Missense_Mutation	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:242002232C>T	ENST00000310397.8	+	17	2282	c.2282C>T	c.(2281-2283)cCg>cTg	p.P761L	SNED1_ENST00000342631.6_Missense_Mutation_p.P761L|SNED1_ENST00000405547.3_Missense_Mutation_p.P761L|SNED1_ENST00000401884.1_Missense_Mutation_p.P761L|AC005237.4_ENST00000458377.1_RNA	NM_001080437.1	NP_001073906.1	Q8TER0	SNED1_HUMAN	sushi, nidogen and EGF-like domains 1	761	EGF-like 11; calcium-binding (Potential).				cell-matrix adhesion	extracellular region	calcium ion binding			NS(1)|breast(1)|central_nervous_system(3)|kidney(2)|large_intestine(6)|lung(4)|ovary(3)|prostate(3)|upper_aerodigestive_tract(1)	24		all_cancers(19;7.48e-31)|all_epithelial(40;1.35e-12)|Breast(86;0.000148)|Renal(207;0.00528)|Ovarian(221;0.104)|Esophageal squamous(248;0.131)|all_lung(227;0.17)|all_hematologic(139;0.182)|Melanoma(123;0.238)		Epithelial(32;6.46e-32)|all cancers(36;6.23e-29)|OV - Ovarian serous cystadenocarcinoma(60;2.1e-14)|Kidney(56;6.35e-09)|KIRC - Kidney renal clear cell carcinoma(57;5.98e-08)|BRCA - Breast invasive adenocarcinoma(100;3.66e-06)|Lung(119;0.00072)|LUSC - Lung squamous cell carcinoma(224;0.00553)|Colorectal(34;0.0162)|COAD - Colon adenocarcinoma(134;0.109)		CGGTCTCAGCCGTGCCTGCAT	0.557000													3	11					0	0	1	0	0
PXDN	7837	broad.mit.edu	37	2	1653369	1653369	+	Missense_Mutation	SNP	C	C	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr2:1653369C>T	ENST00000252804.4	-	17	2233	c.2183G>A	c.(2182-2184)cGc>cAc	p.R728H		NM_012293.1	NP_036425.1	Q92626	PXDN_HUMAN	peroxidasin homolog (Drosophila)	728					extracellular matrix organization|hydrogen peroxide catabolic process|immune response	endoplasmic reticulum|extracellular space|proteinaceous extracellular matrix	extracellular matrix structural constituent|heme binding|interleukin-1 receptor antagonist activity|peroxidase activity	p.R728H(1)		breast(1)|cervix(3)|endometrium(10)|haematopoietic_and_lymphoid_tissue(3)|kidney(6)|large_intestine(24)|lung(48)|ovary(3)|pancreas(8)|prostate(2)|upper_aerodigestive_tract(1)|urinary_tract(3)	112	Acute lymphoblastic leukemia(172;0.0627)|all_hematologic(175;0.0797)	all_cancers(51;0.0845)|Lung NSC(108;0.00641)|all_epithelial(98;0.00716)		all cancers(51;0.0492)|OV - Ovarian serous cystadenocarcinoma(76;0.0973)|Epithelial(75;0.17)|GBM - Glioblastoma multiforme(21;0.228)		GTTGTTCACGCGCCGGTGGGC	0.602000													29	32					0	0	1	0	0
CEACAM20	125931	broad.mit.edu	37	19	45017234	45017234	+	RNA	SNP	C	C	G			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:45017234C>G	ENST00000454753.1	-	0	1702							Q6UY09	CEA20_HUMAN	carcinoembryonic antigen-related cell adhesion molecule 20							integral to membrane				central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(2)|lung(8)|prostate(1)	15		Prostate(69;0.0352)				GTGTTACCGTCTGGCATTTCT	0.582000											OREG0025538	type=REGULATORY REGION|TFbs=CTCF|Dataset=CTCF ChIP-chip sites (Ren lab)|EvidenceSubtype=ChIP-on-chip (ChIP-chip)	18	25					0	0	1	0	0
ZC3H11A	9877	broad.mit.edu	37	1	203786224	203786225	+	Frame_Shift_Ins	INS	-	-	T			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr1:203786224_203786225insT	ENST00000545588.1	+	2	3853_3854	c.26_27insT	c.(25-27)tttfs	p.F9fs	ZC3H11A_ENST00000367214.1_Frame_Shift_Ins_p.F9fs|ZC3H11A_ENST00000367212.3_Frame_Shift_Ins_p.F9fs|ZC3H11A_ENST00000332127.4_Frame_Shift_Ins_p.F9fs|ZC3H11A_ENST00000367210.1_Frame_Shift_Ins_p.F9fs	NM_001271675.1	NP_001258604.1	O75152	ZC11A_HUMAN	zinc finger CCCH-type containing 11A	9							nucleic acid binding|protein binding|zinc ion binding			central_nervous_system(1)|endometrium(7)|kidney(1)|large_intestine(4)|lung(15)|prostate(1)|skin(2)|upper_aerodigestive_tract(1)	32	all_cancers(21;0.0904)|all_epithelial(62;0.234)		BRCA - Breast invasive adenocarcinoma(75;0.109)			GAAGACTGCTATTTTTTTTTCT	0.371													8	244	---	---	---	---					
PTEN	5728	broad.mit.edu	37	10	89712016	89712019	+	Splice_Site	DEL	AGTA	AGTA	-			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr10:89712016_89712019delAGTA	ENST00000371953.3	+	6	1991	c.634_splice	c.e6+1	p.212_splice	PTEN_ENST00000472832.1_3'UTR	NM_000314.4	NP_000305.3	P60484	PTEN_HUMAN	phosphatase and tensin homolog	212	C2 tensin-type.				activation of mitotic anaphase-promoting complex activity|apoptosis|canonical Wnt receptor signaling pathway|cell proliferation|central nervous system development|induction of apoptosis|inositol phosphate dephosphorylation|negative regulation of cell migration|negative regulation of cyclin-dependent protein kinase activity involved in G1/S|negative regulation of focal adhesion assembly|negative regulation of G1/S transition of mitotic cell cycle|negative regulation of protein kinase B signaling cascade|negative regulation of protein phosphorylation|nerve growth factor receptor signaling pathway|phosphatidylinositol dephosphorylation|phosphatidylinositol-mediated signaling|positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process|positive regulation of sequence-specific DNA binding transcription factor activity|protein stabilization|regulation of neuron projection development|T cell receptor signaling pathway	cytosol|internal side of plasma membrane|PML body	anaphase-promoting complex binding|enzyme binding|inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity|lipid binding|magnesium ion binding|PDZ domain binding|phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity|phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity|phosphatidylinositol-3-phosphatase activity|protein serine/threonine phosphatase activity|protein tyrosine phosphatase activity|protein tyrosine/serine/threonine phosphatase activity	p.0?(37)|p.?(11)|p.R55fs*1(5)|p.G165fs*9(3)|p.Y27fs*1(2)|p.G165_*404del(1)		NS(28)|autonomic_ganglia(2)|biliary_tract(6)|bone(5)|breast(92)|central_nervous_system(676)|cervix(26)|endometrium(1068)|eye(8)|haematopoietic_and_lymphoid_tissue(137)|kidney(24)|large_intestine(98)|liver(20)|lung(91)|meninges(2)|oesophagus(2)|ovary(82)|pancreas(6)|prostate(129)|salivary_gland(5)|skin(127)|soft_tissue(19)|stomach(30)|testis(1)|thyroid(29)|upper_aerodigestive_tract(29)|urinary_tract(12)|vulva(17)	2771		all_cancers(4;3.61e-31)|all_epithelial(4;3.96e-23)|Prostate(4;8.12e-23)|Breast(4;0.000111)|Melanoma(5;0.00146)|all_hematologic(4;0.00227)|Colorectal(252;0.00494)|all_neural(4;0.00513)|Acute lymphoblastic leukemia(4;0.0116)|Glioma(4;0.0274)|all_lung(38;0.132)	KIRC - Kidney renal clear cell carcinoma(1;0.214)	UCEC - Uterine corpus endometrioid carcinoma (6;0.000228)|all cancers(1;4.16e-84)|GBM - Glioblastoma multiforme(1;7.77e-49)|Epithelial(1;7.67e-41)|OV - Ovarian serous cystadenocarcinoma(1;6.22e-15)|BRCA - Breast invasive adenocarcinoma(1;1.1e-06)|Lung(2;3.18e-06)|Colorectal(12;4.88e-06)|LUSC - Lung squamous cell carcinoma(2;4.97e-06)|COAD - Colon adenocarcinoma(12;1.13e-05)|Kidney(1;0.000288)|KIRC - Kidney renal clear cell carcinoma(1;0.00037)|STAD - Stomach adenocarcinoma(243;0.218)		CGGAACTTGCAGTAAGTGCTTGAA	0.338		31	"""D, Mis, N, F, S"""		"""glioma,  prostate, endometrial"""	"""harmartoma, glioma,  prostate, endometrial"""			Proteus syndrome;Juvenile Polyposis;Hereditary Mixed Polyposis Syndrome type 1;Cowden syndrome;Bannayan-Riley-Ruvalcaba syndrome	HNSCC(9;0.0022)|TCGA GBM(2;<1E-08)|TSP Lung(26;0.18)			55	15	---	---	---	---					
SERPINB11	89778	broad.mit.edu	37	18	61388270	61388271	+	RNA	DEL	AC	AC	-			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr18:61388270_61388271delAC	ENST00000544088.1	+	0	836				SERPINB11_ENST00000382749.5_RNA|SERPINB11_ENST00000536691.1_RNA|SERPINB11_ENST00000538847.1_RNA	NM_080475.2	NP_536723.2	Q96P15	SPB11_HUMAN	serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)						regulation of proteolysis	cytoplasm	serine-type endopeptidase inhibitor activity			breast(1)|cervix(1)|kidney(1)|lung(3)	6		Esophageal squamous(42;0.129)				GTGCATGTTAACACACACACAC	0.386													2	4	---	---	---	---					
PRR12	57479	broad.mit.edu	37	19	50098262	50098263	+	Frame_Shift_Ins	INS	-	-	C			TCGA-TM-A84B-01A-11D-A36O-08	TCGA-TM-A84B-12A-01D-A367-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	6c782dd9-677c-4812-b310-acbef4325053	15750dd9-70fb-49e2-b349-b02ba6447d41	g.chr19:50098262_50098263insC	ENST00000418929.2	+	4	682_683	c.670_671insC	c.(670-672)cccfs	p.P224fs		NM_020719.1	NP_065770.1	Q9ULL5	PRR12_HUMAN	proline rich 12	4	Pro-rich.						DNA binding			NS(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(1)|lung(2)|pancreas(1)|prostate(2)	11		all_lung(116;2.45e-07)|Lung NSC(112;1.24e-06)|Ovarian(192;0.0728)|all_neural(266;0.0887)		OV - Ovarian serous cystadenocarcinoma(262;0.00319)|GBM - Glioblastoma multiforme(134;0.0132)		TCCAGCCCAGACCCCCCCTTAC	0.703													4	6	---	---	---	---