Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU RBKS 0 genome.wustl.edu 36 2 27923420 27923420 + Missense_Mutation SNP A A C TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 A A A C A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 2 27923420 27923420 A C SNP RBKS NM_022128.1 human genbank 54_36p -1 reviewed missense c.342 p.N114K 1.000 HMMPfam_PfkB,superfamily_SSF53613 PatternScan_PFKB_KINASES_1,PatternScan_PFKB_KINASES_2,HMMPfam_PfkB,superfamily_SSF53613 - no_errors 1349 0 0.00 1449 514 26.18 5 3 37.50 XIRP1 0 genome.wustl.edu 36 3 39200931 39200931 + Silent SNP T T C TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 3 39200931 39200931 T C SNP XIRP1 NM_194293.2 human genbank 54_36p -1 provisional silent c.5010 p.P1670 0.979 NULL HMMPfam_Xin - no_errors 752 2 0.26 819 359 30.09 NA NA NA CACNA2D3 0 genome.wustl.edu 36 3 54908903 54908903 + Missense_Mutation SNP T T C TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 3 54908903 54908903 T C SNP CACNA2D3 NM_018398.2 human genbank 54_36p +1 reviewed missense c.2417 p.L806P 1.000 NULL HMMPfam_VWA,HMMSmart_SM00327,HMMPfam_Cache_1,HMMPfam_VWA_N,superfamily_vWA-like - no_errors 1104 0 0.00 920 437 32.16 NA NA NA ASTE1 0 genome.wustl.edu 36 3 132220212 132220212 + Silent SNP G G A TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 3 132220212 132220212 G A SNP ASTE1 NM_014065.2 human genbank 54_36p -1 validated silent c.1341 p.T447 0.869 NULL HMMPfam_XPG_N,superfamily_SSF88723 - no_errors 928 1 0.11 845 316 27.17 1 3 75.00 DCT 0 genome.wustl.edu 36 13 93919166 93919166 + Missense_Mutation SNP C C T TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 13 93919166 93919166 C T SNP DCT NM_001922.1 human genbank 54_36p -1 validated missense c.430 p.A144T 0.599 superfamily_Di-copper_centre HMMPfam_Tyrosinase,PatternScan_TYROSINASE_1,PatternScan_TYROSINASE_2,superfamily_Di-copper_centre - no_errors 904 0 0.00 833 299 26.41 NA NA NA ENSG00000198229 0 genome.wustl.edu 36 16 33537438 33537438 + Missense_Mutation SNP C C G TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 C C C G C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 16 33537438 33537438 C G SNP ENSG00000198229 ENST00000354689 human ensembl 54_36p +1 known missense c.162 p.H54Q 0.984 HMMSmart_IGv,HMMPfam_V-set,superfamily_SSF48726 HMMSmart_IGv,HMMPfam_V-set,superfamily_SSF48726 - no_stop_codon 648 0 0.00 557 110 16.49 3 1 25.00 FLT3 0 genome.wustl.edu 36 13 27506255 27506256 + In_Frame_Ins INS - - ATCATATTCATATTCTCTGAA TCGA-AB-2980-03A-01D-0739-09 TCGA-AB-2980-11A-01D-0739-09 - - - ATCATATTCATATTCTCTGAA - - Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 2bcd56a1-1367-4b97-8f35-eceb3dce2e4d 3b04b48e-a9fa-4cc9-98a3-e65c1ee56543 13 27506255 27506256 - ATCATATTCATATTCTCTGAA INS FLT3 NM_004119.2 human genbank 54_36p -1 reviewed in_frame_ins c.1801_1800 p.600in_frame_insFREYEYD 1.000:0.998 superfamily_Kinase_like HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726 - no_errors NA NA NA NA NA NA NA NA NA