Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
ELAVL4	0	genome.wustl.edu	36	1	50348217	50348217	+	Silent	SNP	G	G	A			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	1	50348217	50348217	G	A	SNP	ELAVL4	ENST00000371821	human	ensembl	54_36p	+1	known	silent	c.18	p.L6	1.000	NULL	HMMPfam_RRM_1,HMMSmart_RRM,superfamily_SSF54928	-	no_errors	262	36	12.00	121	126	50.20	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25315569	25315569	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	2	25315569	25315569	T	C	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	missense	c.2342	p.D781G	1.000	superfamily_S-adenosyl-L-methionine-dependent methyltransferases	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	59	6	9.23	57	39	40.62	29	54	65.06
DNMT3A	0	genome.wustl.edu	36	2	25324020	25324020	+	Nonsense_Mutation	SNP	G	G	A			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	2	25324020	25324020	G	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	nonsense	c.958	p.R320*	1.000	HMMPfam_PWWP,HMMSmart_SM00293,superfamily_Tudor/PWWP/MBT	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	88	14	13.46	73	59	44.36	40	16	28.57
IDH1	0	genome.wustl.edu	36	2	208821358	208821358	+	Missense_Mutation	SNP	G	G	A	rs121913499		TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	2	208821358	208821358	G	A	SNP	IDH1	NM_005896.2	human	genbank	54_36p	-1	reviewed	missense	c.394	p.R132C	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	94	11	10.48	102	63	37.72	26	38	59.38
TET2	0	genome.wustl.edu	36	4	106410226	106410226	+	Missense_Mutation	SNP	A	A	T			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	4	106410226	106410226	A	T	SNP	TET2	ENST00000265149	human	ensembl	54_36p	+1	known	missense	c.461	p.E154V	1.000	NULL	NULL	-	no_start_codon	152	21	11.86	181	118	39.46	19	19	50.00
SEMA3A	0	genome.wustl.edu	36	7	83430479	83430479	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	7	83430479	83430479	C	T	SNP	SEMA3A	NM_006080.2	human	genbank	54_36p	-1	reviewed	missense	c.1838	p.R613Q	0.991	HMMSmart_IG,HMMPfam_ig,superfamily_SSF48726	HMMPfam_Sema,HMMSmart_Sema,superfamily_Sema,HMMSmart_IG,HMMSmart_PSI,HMMPfam_ig,superfamily_Plexin-like_fold,superfamily_SSF48726	-	no_errors	190	10	4.98	138	34	19.65	NA	NA	NA
FLT3	0	genome.wustl.edu	36	13	27490629	27490629	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	13	27490629	27490629	T	C	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2516	p.D839G	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	171	11	5.98	130	43	24.02	171	59	25.65
PKD1L2	0	genome.wustl.edu	36	16	79738404	79738404	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	16	79738404	79738404	C	T	SNP	PKD1L2	ENST00000299598	human	ensembl	54_36p	-1	known	missense	c.5192	p.R1731K	1.000	NULL	HMMPfam_GPS,HMMSmart_SM00303,PatternScan_CHANNEL_COLICIN,HMMPfam_PLAT,HMMSmart_SM00308,HMMPfam_Lectin_C,HMMSmart_SM00034,superfamily_Lipase/lipooxygenase domain (PLAT/LH2 domain),HMMPfam_PKD_channel,superfamily_C-type lectin-like	-	no_errors	248	38	13.15	78	62	44.29	NA	NA	NA
CCBE1	0	genome.wustl.edu	36	18	55254269	55254269	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	18	55254269	55254269	C	T	SNP	CCBE1	NM_133459.1	human	genbank	54_36p	-1	provisional	missense	c.1072	p.G358R	1.000	NULL	PatternScan_ASX_HYDROXYL,HMMSmart_SM00179,HMMSmart_SM00181,HMMPfam_Collagen,PatternScan_EGF_2,HMMPfam_EGF_CA,PatternScan_EGF_CA,superfamily_EGF/Laminin	-	no_errors	116	21	15.22	118	84	41.38	NA	NA	NA
ZNF99	0	genome.wustl.edu	36	19	22743930	22743930	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	19	22743930	22743930	C	T	SNP	ZNF99	NM_001080409.1	human	genbank	54_36p	-1	provisional	missense	c.103	p.A35T	0.002	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box	HMMPfam_KRAB,HMMSmart_KRAB,superfamily_Krueppel-associated_box,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_ZnF_C2H2,superfamily_SSF57667	-	no_errors	87	16	15.24	85	70	44.59	0	0	0.00
TET2	0	genome.wustl.edu	36	4	106377891	106377891	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AB-2928-03A-01W-0745-08	TCGA-AB-2928-11A-01W-0745-08	C	C	C	-	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	39402967-4dad-4a46-b8d0-5fcb824bc2c2	233dc863-8cfb-4b4d-ad97-ee0685247f3a	4	106377891	106377891	C	-	DEL	TET2	NM_017628.1	human	genbank	54_36p	+1	validated	frame_shift_del	c.3343	p.P1115fs	0.996	NULL	NULL	-	no_errors	72	9	10.84	74	51	39.84	15	9	37.50