Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
MT-CO2	0	genome.wustl.edu	36	MT	8156	8156	+	Silent	SNP	G	G	A			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	MT	8156	8156	G	A	SNP	MT-CO2	ENST00000361739	human	ensembl	54_36p	+1	known	silent	c.570	p.G190	NULL	PatternScan_COX2,HMMPfam_COX2,superfamily_Cupredoxins	PatternScan_COX2,HMMPfam_COX2,superfamily_Cupredoxins,HMMPfam_COX2_TM,superfamily_Cytochrome^^_^^c^^_^^oxidase^^_^^subunit^^_^^II-like^^_^^transmembrane^^_^^region	-	no_errors	2103	2	0.09	940	343	26.71	NA	NA	NA
MTMR8	0	genome.wustl.edu	36	X	63491437	63491437	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	X	63491437	63491437	C	T	SNP	MTMR8	NM_017677.2	human	genbank	54_36p	-1	provisional	missense	c.413	p.R138H	0.799	superfamily_(Phosphotyrosine protein) phosphatases II	HMMSmart_SM00404,HMMPfam_Myotub-related,PatternScan_TYR_PHOSPHATASE_1,superfamily_PH domain-like,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	199	4	1.97	14	53	77.94	0	3	100.00
ITGA10	0	genome.wustl.edu	36	1	144253183	144253183	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	1	144253183	144253183	C	T	SNP	ITGA10	NM_003637.3	human	genbank	54_36p	+1	reviewed	missense	c.3349	p.R1117W	0.811	superfamily_Integrin domains	HMMPfam_VWA,HMMSmart_SM00327,HMMPfam_FG-GAP,HMMSmart_SM00191,HMMPfam_Integrin_alpha2,superfamily_vWA-like,superfamily_Integrin domains,superfamily_Integrin alpha N-terminal domain	-	no_errors	282	0	0.00	78	75	48.39	NA	NA	NA
LRP1B	0	genome.wustl.edu	36	2	141243252	141243252	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	2	141243252	141243252	C	T	SNP	LRP1B	NM_018557.2	human	genbank	54_36p	-1	validated	missense	c.5758	p.E1920K	1.000	HMMSmart_LY,superfamily_SSF63825	HMMPfam_Ldl_recept_b,HMMSmart_LY,PatternScan_ASX_HYDROXYL,HMMPfam_NHL,HMMSmart_EGF_CA,HMMPfam_Ldl_recept_a,HMMSmart_LDLa,PatternScan_LDLRA_1,superfamily_LDL_rcpt_classA_cys-rich,HMMPfam_EGF,HMMSmart_EGF,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,superfamily_SSF57196,superfamily_SSF63825	-	no_errors	104	0	0.00	39	28	41.79	NA	NA	NA
XIRP2	0	genome.wustl.edu	36	2	167815650	167815650	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	2	167815650	167815650	G	A	SNP	XIRP2	NM_152381.2	human	genbank	54_36p	+1	validated	missense	c.9502	p.A3168T	0.001	NULL	HMMPfam_Xin	-	no_errors	179	0	0.00	50	43	46.24	1	0	0.00
BSN	0	genome.wustl.edu	36	3	49664602	49664602	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	3	49664602	49664602	C	T	SNP	BSN	NM_003458.3	human	genbank	54_36p	+1	validated	missense	c.2609	p.A870V	1.000	NULL	HMMPfam_zf-piccolo,superfamily_FYVE_PHD_ZnF	-	no_errors	65	0	0.00	1	8	88.89	NA	NA	NA
FAM40B	0	genome.wustl.edu	36	7	128881232	128881232	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	7	128881232	128881232	T	C	SNP	FAM40B	NM_020704.1	human	genbank	54_36p	+1	validated	missense	c.544	p.C182R	1.000	HMMPfam_N1221	HMMPfam_N1221	-	no_errors	215	0	0.00	10	21	67.74	NA	NA	NA
RFX3	0	genome.wustl.edu	36	9	3261010	3261010	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	9	3261010	3261010	C	T	SNP	RFX3	NM_134428.2	human	genbank	54_36p	-1	reviewed	missense	c.1195	p.E399K	1.000	NULL	"HMMPfam_RFX_DNA_binding,HMMPfam_RFX1_trans_act,superfamily_""Winged helix"" DNA-binding domain"	-	no_errors	386	0	0.00	93	68	42.24	11	7	38.89
MRE11A	0	genome.wustl.edu	36	11	93832293	93832293	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	11	93832293	93832293	G	C	SNP	MRE11A	NM_005591.3	human	genbank	54_36p	-1	reviewed	missense	c.1429	p.Q477E	1.000	NULL	HMMPfam_Metallophos,HMMPfam_Mre11_DNA_bind,superfamily_Metallo-dependent phosphatases	-	no_errors	331	1	0.30	165	76	31.40	53	35	39.77
PTPN11	0	genome.wustl.edu	36	12	111372546	111372546	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	12	111372546	111372546	G	T	SNP	PTPN11	NM_002834.3	human	genbank	54_36p	+1	reviewed	missense	c.179	p.G60V	1.000	HMMPfam_SH2,HMMSmart_SM00252,superfamily_SH2 domain	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_SH2,HMMSmart_SM00252,HMMSmart_SM00404,PatternScan_TYR_PHOSPHATASE_1,superfamily_(Phosphotyrosine protein) phosphatases II,superfamily_SH2 domain	-	no_errors	62	0	0.00	52	16	23.19	75	47	38.52
TP53	0	genome.wustl.edu	36	17	7518997	7518997	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	17	7518997	7518997	G	A	SNP	TP53	NM_000546.4	human	genbank	54_36p	-1	reviewed	missense	c.577	p.H193Y	1.000	superfamily_p53-like transcription factors,HMMPfam_P53	PatternScan_P53,superfamily_p53-like transcription factors,HMMPfam_P53_tetramer,superfamily_p53 tetramerization domain,HMMPfam_P53,HMMPfam_P53_TAD	-	no_errors	161	0	0.00	17	68	79.07	1	149	99.33
ASXL3	0	genome.wustl.edu	36	18	29568298	29568298	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	18	29568298	29568298	C	T	SNP	ASXL3	NM_030632.1	human	genbank	54_36p	+1	validated	missense	c.1003	p.R335W	1.000	NULL	NULL	-	no_errors	131	0	0.00	15	39	72.22	NA	NA	NA
PTPRT	0	genome.wustl.edu	36	20	40180498	40180498	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	20	40180498	40180498	C	T	SNP	PTPRT	NM_133170.5	human	genbank	54_36p	-1	reviewed	missense	c.2998	p.A1000T	0.987	HMMPfam_Y_phosphatase,HMMSmart_SM00194,superfamily_(Phosphotyrosine protein) phosphatases II	HMMPfam_Y_phosphatase,HMMSmart_SM00194,HMMPfam_MAM,HMMSmart_SM00137,PatternScan_MAM_1,HMMSmart_SM00404,HMMPfam_fn3,HMMSmart_SM00060,superfamily_Fibronectin type III,PatternScan_TYR_PHOSPHATASE_1,superfamily_Immunoglobulin,superfamily_(Phosphotyrosine protein) phosphatases II	-	no_errors	234	0	0.00	58	39	40.21	NA	NA	NA
FOXP4	0	genome.wustl.edu	36	6	41663552	41663553	+	Frame_Shift_Ins	INS	-	-	A			TCGA-AB-2885-03A-01W-0732-08	TCGA-AB-2885-11A-01W-0732-08	-	-	-	A	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	d5c78933-a17c-449c-a24d-730ea0f7a9cd	f62da227-622a-4139-9229-acd0939a17c3	6	41663552	41663553	-	A	INS	FOXP4	NM_001012426.1	human	genbank	54_36p	+1	reviewed	frame_shift_ins	c.916_917	p.H306fs	1.000:1.000	NULL	"HMMPfam_Fork_head,HMMSmart_SM00339,PatternScan_ZINC_FINGER_C2H2_1,PatternScan_FORK_HEAD_2,superfamily_""Winged helix"" DNA-binding domain"	-	no_errors	48	0	0.00	11	5	31.25	1	0	0.00