Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name start stop reference variant type gene_name transcript_name transcript_species transcript_source transcript_version strand transcript_status trv_type c_position amino_acid_change ucsc_cons domain all_domains deletion_substructures transcript_error NormalRefReads_WU NormalVarReads_WU NormalVAF_WU TumorRefReads_WU TumorVarReads_WU TumorVAF_WU RNARefReads_WU RNAVarReads_WU RNAVAF_WU ITGB5 0 genome.wustl.edu 36 3 126010604 126010604 + Silent SNP G G A TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 3 126010604 126010604 G A SNP ITGB5 NM_002213.3 human genbank 54_36p -1 provisional silent c.1218 p.S406 1.000 HMMPfam_Integrin_beta,HMMSmart_INB,superfamily_SSF69179 HMMSmart_VWA,HMMPfam_Integrin_beta,HMMSmart_INB,HMMSmart_PSI,HMMSmart_EGF,HMMPfam_Integrin_B_tail,superfamily_Integrin_bsu_tail,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_2,HMMPfam_Integrin_b_cyt,PatternScan_INTEGRIN_BETA,superfamily_SSF53300,superfamily_SSF57196,superfamily_SSF69179 - no_errors 131 8 5.63 125 82 39.61 6 6 50.00 LRRC15 0 genome.wustl.edu 36 3 195561630 195561630 + Missense_Mutation SNP C C T TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 3 195561630 195561630 C T SNP LRRC15 NM_130830.1 human genbank 54_36p -1 validated missense c.1438 p.E480K 0.003 NULL HMMSmart_LRRNT,HMMSmart_LRRCT,HMMPfam_LRR_1,HMMSmart_LRR_TYP,superfamily_SSF52058 - no_errors 156 4 2.48 170 48 21.92 NA NA NA KIT 0 genome.wustl.edu 36 4 55294077 55294077 + Missense_Mutation SNP G G T rs121913506 TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 4 55294077 55294077 G T SNP KIT NM_000222.2 human genbank 54_36p +1 reviewed missense c.2446 p.D816Y 1.000 HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,HMMSmart_IGc2,HMMSmart_IG,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726 - no_errors 53 2 3.64 111 40 26.32 172 71 29.22 KLHL2 0 genome.wustl.edu 36 4 166454642 166454642 + Missense_Mutation SNP A A T TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 A A A T A A Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 4 166454642 166454642 A T SNP KLHL2 NM_007246.2 human genbank 54_36p +1 provisional missense c.1483 p.N495Y 1.000 HMMPfam_Kelch_1,HMMSmart_Kelch,superfamily_Gal_oxid_central HMMSmart_BTB,HMMPfam_Kelch_1,HMMSmart_Kelch,superfamily_Gal_oxid_central,superfamily_BTB/POZ_fold,HMMPfam_BACK,HMMPfam_BTB - no_errors 250 9 3.45 169 116 40.00 21 11 34.38 ESM1 0 genome.wustl.edu 36 5 54316851 54316851 + Silent SNP C C T TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 5 54316851 54316851 C T SNP ESM1 NM_007036.1 human genbank 54_36p -1 reviewed silent c.252 p.Q84 0.995 HMMSmart_IB HMMSmart_IB - no_errors 48 5 9.43 62 51 44.35 NA NA NA C6orf170 0 genome.wustl.edu 36 6 121475960 121475960 + Missense_Mutation SNP T T C TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 T T T C T T Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 6 121475960 121475960 T C SNP C6orf170 NM_152730.4 human genbank 54_36p -1 validated missense c.3116 p.K1039R 1.000 NULL superfamily_Ypt/Rab-GAP domain of gyp1p - no_errors 89 3 3.26 139 97 40.76 3 1 25.00 RUNX1T1 0 genome.wustl.edu 36 8 93073230 93073230 + Nonsense_Mutation SNP G G T TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 G G G T G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 8 93073230 93073230 G T SNP RUNX1T1 NM_175634.2 human genbank 54_36p -1 reviewed nonsense c.804 p.C268* 1.000 NULL HMMPfam_zf-MYND,PatternScan_ZF_MYND_1,HMMPfam_TAFH,HMMSmart_SM00549,HMMPfam_NHR2 - no_errors 161 10 5.78 154 102 39.38 NA NA NA SOGA2 0 genome.wustl.edu 36 18 8796946 8796946 + Missense_Mutation SNP G G A TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 G G G A G G Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 18 8796946 8796946 G A SNP KIAA0802 NM_015210.3 human genbank 54_36p +1 predicted missense c.2492 p.R831H 0.050 NULL NULL - no_errors 54 0 0.00 73 20 21.28 NA NA NA GNA15 0 genome.wustl.edu 36 19 3101277 3101277 + Missense_Mutation SNP C C T TCGA-AB-2881-03A-01W-0732-08 TCGA-AB-2881-11A-01W-0732-08 C C C T C C Verified Valid Somatic Phase_IV WXS Hybrid_Capture_Illumina_Seq 1 dbGAP Illumina HiSeq 82b9b9ce-b995-45f0-bf39-53cb56684024 510d78d5-f5a3-4be9-bb94-19f320ca3252 19 3101277 3101277 C T SNP GNA15 NM_002068.2 human genbank 54_36p +1 validated missense c.479 p.A160V 0.608 HMMPfam_G-alpha,superfamily_Transducin (alpha subunit) insertion domain,HMMSmart_SM00275,superfamily_P-loop containing nucleoside triphosphate hydrolases HMMPfam_G-alpha,superfamily_Transducin (alpha subunit) insertion domain,HMMSmart_SM00275,superfamily_P-loop containing nucleoside triphosphate hydrolases - no_errors 30 0 0.00 22 13 36.11 109 143 56.08