Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
B4GALT3	0	genome.wustl.edu	36	1	159410135	159410135	+	Silent	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	1	159410135	159410135	C	T	SNP	B4GALT3	NM_003779.2	human	genbank	54_36p	-1	reviewed	silent	c.687	p.P229	0.701	HMMPfam_Galactosyl_T_2,superfamily_Nucleotide-diphospho-sugar transferases	HMMPfam_Galactosyl_T_2,superfamily_Nucleotide-diphospho-sugar transferases	-	no_errors	611	17	2.70	109	76	40.86	35	45	55.56
DNMT3A	0	genome.wustl.edu	36	2	25320536	25320536	+	Nonsense_Mutation	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	2	25320536	25320536	G	A	SNP	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	nonsense	c.1843	p.Q615*	1.000	NULL	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	46	0	0.00	5	8	61.54	10	4	28.57
WIPF1	0	genome.wustl.edu	36	2	175140981	175140981	+	Missense_Mutation	SNP	G	G	C			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	C	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	2	175140981	175140981	G	C	SNP	WIPF1	NM_001077269.1	human	genbank	54_36p	-1	reviewed	missense	c.1196	p.P399R	1.000	NULL	HMMPfam_WH2,HMMSmart_SM00246	-	no_errors	182	2	1.09	37	32	46.38	37	33	47.14
ZNF197	0	genome.wustl.edu	36	3	44649065	44649065	+	Silent	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	3	44649065	44649065	C	T	SNP	ZNF197	NM_006991.1	human	genbank	54_36p	+1	reviewed	silent	c.739	p.L247	0.997	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352)	HMMPfam_KRAB,HMMSmart_SM00349,superfamily_KRAB domain (Kruppel-associated box Pfam 01352),HMMPfam_SCAN,HMMSmart_SM00431,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	232	15	6.07	129	96	42.48	4	3	42.86
MEPE	0	genome.wustl.edu	36	4	88986411	88986411	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	4	88986411	88986411	G	A	SNP	MEPE	NM_020203.2	human	genbank	54_36p	+1	validated	missense	c.1367	p.G456D	0.000	NULL	HMMPfam_Osteoregulin	-	no_errors	282	8	2.76	50	27	35.06	NA	NA	NA
VARS	0	genome.wustl.edu	36	6	31860190	31860190	+	Silent	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	6	31860190	31860190	G	A	SNP	VARS	NM_006295.2	human	genbank	54_36p	-1	reviewed	silent	c.1536	p.F512	1.000	HMMPfam_tRNA-synt_1,superfamily_ValRS/IleRS/LeuRS editing domain,superfamily_Nucleotidylyl transferase	PatternScan_AA_TRNA_LIGASE_I,HMMPfam_tRNA-synt_1,HMMPfam_GST_N,HMMPfam_GST_C,superfamily_ValRS/IleRS/LeuRS editing domain,superfamily_Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases,superfamily_Glutathione S-transferase (GST) C-terminal domain,HMMPfam_Anticodon_1,superfamily_Nucleotidylyl transferase	-	no_errors	110	3	2.63	15	12	44.44	65	85	56.67
PGM3	0	genome.wustl.edu	36	6	83938402	83938402	+	Missense_Mutation	SNP	A	A	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	6	83938402	83938402	A	T	SNP	PGM3	NM_015599.1	human	genbank	54_36p	-1	provisional	missense	c.1338	p.D446E	0.937	superfamily_Phosphoglucomutase C-terminal domain	HMMPfam_PGM_PMM_IV,HMMPfam_PGM_PMM_I,superfamily_Phosphoglucomutase first 3 domains,PatternScan_PGM_PMM,superfamily_Phosphoglucomutase C-terminal domain	-	no_errors	219	6	2.65	96	77	44.51	6	4	40.00
HDAC2	0	genome.wustl.edu	36	6	114381250	114381250	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	6	114381250	114381250	C	T	SNP	HDAC2	NM_001527.2	human	genbank	54_36p	-1	reviewed	missense	c.805	p.D269N	1.000	HMMPfam_Hist_deacetyl,superfamily_SSF52768	HMMPfam_Hist_deacetyl,superfamily_SSF52768	-	no_errors	90	0	0.00	80	42	34.15	58	40	40.82
ARHGEF5	0	genome.wustl.edu	36	7	143693292	143693292	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	7	143693292	143693292	G	A	SNP	ARHGEF5	NM_005435.3	human	genbank	54_36p	+1	reviewed	missense	c.2597	p.R866Q	0.023	NULL	HMMPfam_RhoGEF,HMMSmart_SM00325,superfamily_DBL homology domain (DH-domain),PatternScan_DH_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_SH3_2,superfamily_PH domain-like	-	no_errors	573	0	0.00	475	65	12.04	NA	NA	NA
TUSC3	0	genome.wustl.edu	36	8	15525008	15525008	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	8	15525008	15525008	C	T	SNP	TUSC3	NM_006765.2	human	genbank	54_36p	+1	reviewed	missense	c.187	p.R63C	1.000	HMMPfam_OST3_OST6,superfamily_Thioredoxin-like	HMMPfam_OST3_OST6,superfamily_Thioredoxin-like	-	no_errors	86	0	0.00	108	46	29.87	NA	NA	NA
BNC2	0	genome.wustl.edu	36	9	16426735	16426735	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	9	16426735	16426735	C	T	SNP	BNC2	NM_017637.5	human	genbank	54_36p	-1	validated	missense	c.1457	p.R486H	1.000	HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,HMMSmart_SM00355,superfamily_C2H2 and C2HC zinc fingers	-	no_errors	648	3	0.46	127	45	26.16	NA	NA	NA
BTBD16	0	genome.wustl.edu	36	10	124024603	124024603	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	10	124024603	124024603	C	T	SNP	BTBD16	NM_144587.2	human	genbank	54_36p	+1	validated	missense	c.17	p.T6M	0.000	NULL	superfamily_POZ domain,HMMPfam_BTB	-	no_errors	353	1	0.28	102	73	41.71	NA	NA	NA
KRAS	0	genome.wustl.edu	36	12	25289551	25289551	+	Missense_Mutation	SNP	C	C	A	rs121913529		TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	12	25289551	25289551	C	A	SNP	KRAS	NM_033360.3	human	genbank	54_36p	-1	reviewed	missense	c.35	p.G12V	1.000	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMSmart_SM00176,HMMSmart_SM00173,HMMSmart_SM00174,HMMSmart_SM00175,HMMPfam_Ras,superfamily_P-loop containing nucleoside triphosphate hydrolases	-	no_errors	30	1	3.23	35	15	30.00	18	9	33.33
LOC642458	0	genome.wustl.edu	36	14	18546106	18546106	+	RNA	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	14	18546106	18546106	G	A	SNP	LOC642458	XR_016116.2	human	genbank	54_36p	-1	model	rna	NULL	NULL	0.986	-	-	-	pseudogene	156	2	1.27	162	23	12.43	0	1	100.00
MEFV	0	genome.wustl.edu	36	16	3234588	3234588	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	16	3234588	3234588	C	T	SNP	MEFV	NM_000243.2	human	genbank	54_36p	-1	reviewed	missense	c.1612	p.A538T	0.911	NULL	HMMPfam_zf-B_box,HMMSmart_SM00336,HMMPfam_SPRY,HMMPfam_PAAD_DAPIN,HMMSmart_SM00589,superfamily_DEATH domain,HMMSmart_SM00449,superfamily_B-box zinc-binding domain	-	no_errors	205	15	6.82	22	31	58.49	10	5	33.33
NOMO2	0	genome.wustl.edu	36	16	18439649	18439649	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	16	18439649	18439649	C	T	SNP	NOMO2	NM_001004060.1	human	genbank	54_36p	-1	reviewed	missense	c.2212	p.V738M	0.986	NULL	HMMPfam_Cna_B,superfamily_Carboxypeptidase regulatory domain,superfamily_Starch-binding domain-like	-	no_errors	517	24	4.42	97	35	26.52	65	48	42.48
CACNG1	0	genome.wustl.edu	36	17	62471268	62471268	+	Silent	SNP	C	C	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	17	62471268	62471268	C	T	SNP	CACNG1	NM_000727.2	human	genbank	54_36p	+1	reviewed	silent	c.30	p.R10	0.962	HMMPfam_PMP22_Claudin	HMMPfam_PMP22_Claudin	-	no_errors	118	8	6.35	8	8	50.00	NA	NA	NA
KATNAL2	0	genome.wustl.edu	36	18	42879702	42879702	+	Missense_Mutation	SNP	C	C	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	18	42879702	42879702	C	A	SNP	KATNAL2	NM_031303.1	human	genbank	54_36p	+1	provisional	missense	c.1086	p.H362Q	0.999	HMMPfam_AAA,superfamily_SSF52540	HMMSmart_AAA,HMMPfam_AAA,superfamily_SSF52540	-	no_errors	223	2	0.89	39	34	46.58	3	0	0.00
WDR87	0	genome.wustl.edu	36	19	43075963	43075963	+	Silent	SNP	A	A	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	19	43075963	43075963	A	T	SNP	WDR87	ENST00000303868	human	ensembl	54_36p	-1	known	silent	c.2103	p.I701	1.000	NULL	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_C_TYPE_LECTIN_1,HMMPfam_WD40	-	no_stop_codon	535	17	3.07	75	62	45.26	NA	NA	NA
GRWD1	0	genome.wustl.edu	36	19	53646208	53646208	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	19	53646208	53646208	G	A	SNP	GRWD1	NM_031485.2	human	genbank	54_36p	+1	provisional	missense	c.931	p.V311I	0.990	HMMSmart_SM00320,superfamily_WD40 repeat-like,HMMPfam_WD40	HMMSmart_SM00320,superfamily_WD40 repeat-like,PatternScan_WD_REPEATS_1,HMMPfam_WD40	-	no_errors	122	0	0.00	21	7	25.00	48	22	31.43
U2AF1	0	genome.wustl.edu	36	21	43397525	43397525	+	Missense_Mutation	SNP	G	G	T			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	G	G	G	T	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	21	43397525	43397525	G	T	SNP	U2AF1	NM_001025203.1	human	genbank	54_36p	-1	reviewed	missense	c.101	p.S34Y	1.000	HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1	HMMPfam_RRM_1,HMMSmart_RRM,HMMPfam_zf-CCCH,HMMSmart_ZnF_C3H1,superfamily_SSF54928	-	no_errors	175	5	2.76	15	8	33.33	103	113	52.31
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2861-03B-01W-0728-08	TCGA-AB-2861-11B-01W-0729-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	6f4de42a-16ce-4536-b5a7-a9380540dda4	c2a59421-c7d4-4b57-a82d-ee675481ba9b	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA