Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
BUB1	0	genome.wustl.edu	36	2	111135776	111135776	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	2	111135776	111135776	G	A	SNP	BUB1	NM_004336.3	human	genbank	54_36p	-1	reviewed	missense	c.1073	p.A358V	0.000	NULL	HMMSmart_SM00220,PatternScan_PROTEIN_KINASE_ST,superfamily_Protein kinase-like (PK-like),HMMPfam_Mad3_BUB1_I,HMMSmart_SM00777,PatternScan_PROTEIN_KINASE_ATP	-	no_errors	219	14	5.96	85	48	35.56	1	1	50.00
TPRG1	0	genome.wustl.edu	36	3	190521248	190521248	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	3	190521248	190521248	T	C	SNP	TPRG1	NM_198485.3	human	genbank	54_36p	+1	validated	missense	c.773	p.I258T	1.000	NULL	NULL	-	no_errors	133	10	6.99	109	104	48.83	1	0	0.00
SULF1	0	genome.wustl.edu	36	8	70698766	70698766	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	8	70698766	70698766	C	T	SNP	SULF1	NM_015170.1	human	genbank	54_36p	+1	validated	missense	c.1630	p.R544C	1.000	superfamily_Alkaline_phosphatase_core	HMMPfam_Sulfatase,PatternScan_SULFATASE_2,PatternScan_SULFATASE_1,superfamily_Alkaline_phosphatase_core	-	no_errors	47	2	4.08	57	38	40.00	NA	NA	NA
SMC3	0	genome.wustl.edu	36	10	112332346	112332346	+	Nonsense_Mutation	SNP	A	A	T			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	A	A	A	T	A	A	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	10	112332346	112332346	A	T	SNP	SMC3	NM_005445.3	human	genbank	54_36p	+1	reviewed	nonsense	c.760	p.R254*	1.000	HMMPfam_SMC_N,superfamily_P-loop containing nucleoside triphosphate hydrolases	HMMPfam_SMC_N,HMMPfam_SMC_hinge,superfamily_Smc hinge domain,PatternScan_ABC_TRANSPORTER_1,superfamily_P-loop containing nucleoside triphosphate hydrolases,superfamily_BAG domain	-	no_errors	49	5	9.26	63	41	39.42	39	4	9.30
FLT3	0	genome.wustl.edu	36	13	27490642	27490642	+	Missense_Mutation	SNP	C	C	A	rs121913488		TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	13	27490642	27490642	C	A	SNP	FLT3	NM_004119.2	human	genbank	54_36p	-1	reviewed	missense	c.2503	p.D835Y	1.000	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,superfamily_Kinase_like	HMMPfam_Pkinase_Tyr,HMMSmart_TyrKc,PatternScan_RECEPTOR_TYR_KIN_III,PatternScan_PROTEIN_KINASE_TYR,superfamily_Kinase_like,HMMPfam_ig,PatternScan_PROTEIN_KINASE_ATP,superfamily_SSF48726	-	no_errors	69	10	12.66	21	12	36.36	184	175	48.75
RYR1	0	genome.wustl.edu	36	19	43730855	43730855	+	Silent	SNP	C	C	T			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	19	43730855	43730855	C	T	SNP	RYR1	NM_000540.2	human	genbank	54_36p	+1	reviewed	silent	c.12237	p.Y4079	0.998	superfamily_EF-hand	HMMPfam_RYDR_ITPR,HMMPfam_RyR,HMMPfam_MIR,superfamily_MIR domain (Pfam 02815),HMMPfam_SPRY,HMMPfam_Ion_trans,HMMPfam_RR_TM4-6,HMMPfam_RIH_assoc,HMMPfam_Ins145_P3_rec,HMMSmart_SM00472,HMMSmart_SM00449,superfamily_EF-hand	-	no_errors	177	15	7.81	29	25	46.30	NA	NA	NA
DNMT3A	0	genome.wustl.edu	36	2	25320534	25320534	+	Frame_Shift_Del	DEL	C	C	-			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	C	C	C	-	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	2	25320534	25320534	C	-	DEL	DNMT3A	NM_022552.3	human	genbank	54_36p	-1	reviewed	frame_shift_del	c.1845	p.E616fs	1.000	NULL	HMMPfam_PWWP,HMMSmart_SM00293,HMMPfam_DNA_methylase,superfamily_FYVE/PHD zinc finger,PatternScan_C5_MTASE_1,superfamily_S-adenosyl-L-methionine-dependent methyltransferases,superfamily_Tudor/PWWP/MBT	-	no_errors	10	0	0.00	17	0	0.00	8	0	0.00
U2AF2	0	genome.wustl.edu	36	19	60865717	60865718	+	Frame_Shift_Ins	INS	-	-	G			TCGA-AB-2851-03B-01W-0728-08	TCGA-AB-2851-11B-01W-0729-08	-	-	-	G	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	1c8aef61-92b6-4a35-9a7f-89f5acf8265e	3d4d70a0-64f8-49a8-bc2d-d34a239168b5	19	60865717	60865718	-	G	INS	U2AF2	NM_007279.1	human	genbank	54_36p	+1	reviewed	frame_shift_ins	c.524_525	p.L178fs	0.997:0.995	HMMPfam_RRM_1,HMMSmart_SM00360,superfamily_RNA-binding domain RBD	HMMPfam_RRM_1,HMMSmart_SM00360,superfamily_RNA-binding domain RBD	-	no_errors	12	0	0.00	6	3	33.33	46	0	0.00