Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_Position	End_Position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_File	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	chromosome_name	start	stop	reference	variant	type	gene_name	transcript_name	transcript_species	transcript_source	transcript_version	strand	transcript_status	trv_type	c_position	amino_acid_change	ucsc_cons	domain	all_domains	deletion_substructures	transcript_error	NormalRefReads_WU	NormalVarReads_WU	NormalVAF_WU	TumorRefReads_WU	TumorVarReads_WU	TumorVAF_WU	RNARefReads_WU	RNAVarReads_WU	RNAVAF_WU
DMD	0	genome.wustl.edu	36	X	31764826	31764826	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	X	31764826	31764826	G	A	SNP	DMD	NM_004006.2	human	genbank	54_36p	-1	reviewed	missense	c.7130	p.P2377L	1.000	superfamily_Spectrin repeat	HMMPfam_ZZ,HMMSmart_SM00291,PatternScan_ZF_ZZ_1,HMMPfam_WW,HMMSmart_SM00456,PatternScan_WW_DOMAIN_1,superfamily_WW domain,PatternScan_ACTININ_1,PatternScan_ACTININ_2,HMMPfam_CH,HMMSmart_SM00033,HMMPfam_Spectrin,superfamily_Prefoldin,superfamily_t-snare proteins,HMMPfam_efhand_1,HMMPfam_efhand_2,superfamily_Calponin-homology domain CH-domain,HMMSmart_SM00150,superfamily_Spectrin repeat,superfamily_EF-hand	-	no_errors	112	9	7.38	209	161	42.93	NA	NA	NA
GPR88	0	genome.wustl.edu	36	1	100777515	100777515	+	Silent	SNP	C	C	A			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	A	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	1	100777515	100777515	C	A	SNP	GPR88	NM_022049.2	human	genbank	54_36p	+1	validated	silent	c.405	p.A135	0.994	HMMPfam_7tm_1,superfamily_SSF81321	HMMPfam_7tm_1,PatternScan_G_PROTEIN_RECEP_F1_1,superfamily_SSF81321	-	no_errors	15	1	6.25	18	21	52.50	NA	NA	NA
DCAF6	0	genome.wustl.edu	36	1	166227168	166227168	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	1	166227168	166227168	T	C	SNP	IQWD1	NM_018442.1	human	genbank	54_36p	+1	validated	missense	c.655	p.Y219H	1.000	HMMSmart_WD40,superfamily_WD40_like,HMMPfam_WD40	HMMSmart_IQ,HMMSmart_WD40,superfamily_WD40_like,HMMPfam_WD40	-	no_errors	68	17	20.00	122	116	48.33	8	10	55.56
CELSR3	0	genome.wustl.edu	36	3	48674114	48674114	+	Missense_Mutation	SNP	T	T	C			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	T	T	T	C	T	T	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	3	48674114	48674114	T	C	SNP	CELSR3	NM_001407.2	human	genbank	54_36p	-1	reviewed	missense	c.958	p.N320D	1.000	NULL	PatternScan_ASX_HYDROXYL,HMMPfam_GPS,HMMSmart_SM00303,HMMPfam_7tm_2,HMMSmart_SM00282,HMMPfam_HRM,HMMSmart_SM00008,HMMSmart_SM00179,HMMPfam_Laminin_EGF,HMMSmart_SM00180,PatternScan_EGF_LAM_1,HMMPfam_Cadherin,HMMSmart_SM00112,PatternScan_CADHERIN_1,HMMPfam_EGF,HMMSmart_SM00181,superfamily_Concanavalin A-like lectins/glucanases,HMMPfam_Laminin_G_2,PatternScan_EGF_1,PatternScan_EGF_2,superfamily_Cadherin-like,PatternScan_G_PROTEIN_RECEP_F2_2,superfamily_EGF/Laminin	-	no_errors	78	6	7.14	30	34	53.12	NA	NA	NA
CADPS	0	genome.wustl.edu	36	3	62493667	62493667	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	3	62493667	62493667	C	T	SNP	CADPS	NM_003716.3	human	genbank	54_36p	-1	reviewed	missense	c.2210	p.R737Q	1.000	NULL	HMMPfam_C2,HMMPfam_PH,HMMSmart_SM00233,HMMPfam_DUF1041,superfamily_PH domain-like	-	no_errors	238	12	4.80	135	111	44.40	NA	NA	NA
CMYA5	0	genome.wustl.edu	36	5	79063408	79063408	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	5	79063408	79063408	G	A	SNP	CMYA5	NM_153610.3	human	genbank	54_36p	+1	validated	missense	c.3064	p.E1022K	0.262	NULL	HMMPfam_SPRY,HMMPfam_fn3,HMMSmart_FN3,superfamily_FN_III-like	-	no_errors	188	14	6.93	203	169	44.83	NA	NA	NA
FCHSD1	0	genome.wustl.edu	36	5	141009287	141009287	+	Silent	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	5	141009287	141009287	C	T	SNP	FCHSD1	NM_033449.1	human	genbank	54_36p	-1	provisional	silent	c.234	p.R78	0.999	HMMPfam_FCH,HMMSmart_SM00055	HMMPfam_FCH,HMMSmart_SM00055,HMMPfam_SH3_1,HMMSmart_SM00326,superfamily_SH3-domain,HMMPfam_SH3_2	-	no_errors	195	21	9.72	51	34	39.53	0	0	0.00
LOC442255	0	genome.wustl.edu	36	6	122017543	122017543	+	RNA	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	6	122017543	122017543	C	T	SNP	LOC442255	XR_016618.2	human	genbank	54_36p	+1	model	rna	NULL	NULL	0.047	-	-	-	pseudogene	215	23	9.62	189	157	45.24	35	0	0.00
SMOC2	0	genome.wustl.edu	36	6	168750815	168750815	+	Missense_Mutation	SNP	G	G	A			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	6	168750815	168750815	G	A	SNP	SMOC2	NM_022138.1	human	genbank	54_36p	+1	provisional	missense	c.911	p.R304Q	0.973	NULL	HMMPfam_Thyroglobulin_1,HMMSmart_TY,PatternScan_THYROGLOBULIN_1_1,superfamily_Thyroglobulin_1,HMMSmart_EFh,HMMPfam_Kazal_1,HMMSmart_KAZAL,PatternScan_EF_HAND_1,HMMPfam_SPARC_Ca_bdg,superfamily_SSF47473	-	no_errors	70	9	11.39	28	29	50.88	NA	NA	NA
UNC5B	0	genome.wustl.edu	36	10	72721224	72721224	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	10	72721224	72721224	C	T	SNP	UNC5B	NM_170744.3	human	genbank	54_36p	+1	validated	missense	c.1324	p.P442S	1.000	NULL	HMMPfam_Death,HMMSmart_SM00005,HMMPfam_TSP_1,HMMSmart_SM00209,superfamily_TSP-1 type 1 repeat,HMMPfam_ZU5,HMMSmart_SM00218,HMMSmart_SM00408,HMMSmart_SM00409,superfamily_DEATH domain,HMMPfam_I-set,superfamily_Immunoglobulin	-	no_errors	171	14	7.57	48	32	39.02	NA	NA	NA
IDH2	0	genome.wustl.edu	36	15	88432938	88432938	+	Missense_Mutation	SNP	C	C	T	rs121913502		TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	15	88432938	88432938	C	T	SNP	IDH2	NM_002168.2	human	genbank	54_36p	-1	reviewed	missense	c.419	p.R140Q	1.000	HMMPfam_Iso_dh,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	HMMPfam_Iso_dh,PatternScan_IDH_IMDH,superfamily_Isocitrate/Isopropylmalate dehydrogenase-like	-	no_errors	186	20	9.66	64	49	42.98	153	162	51.27
TSHZ3	0	genome.wustl.edu	36	19	36461818	36461818	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	19	36461818	36461818	C	T	SNP	TSHZ3	NM_020856.2	human	genbank	54_36p	-1	validated	missense	c.721	p.D241N	1.000	NULL	HMMPfam_Homeobox,HMMSmart_HOX,HMMPfam_zf-C2H2,PatternScan_ZINC_FINGER_C2H2_1,superfamily_Homeodomain_like,HMMSmart_ZnF_C2H2,PatternScan_HOMEOBOX_1	-	no_errors	1001	126	11.14	164	146	46.79	NA	NA	NA
MEGF8	0	genome.wustl.edu	36	19	47530112	47530112	+	Silent	SNP	G	G	A			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	G	G	G	A	G	G	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	19	47530112	47530112	G	A	SNP	MEGF8	NM_001410.2	human	genbank	54_36p	+1	validated	silent	c.465	p.P155	0.000	HMMSmart_EGF	PatternScan_ASX_HYDROXYL,HMMPfam_CUB,HMMSmart_CUB,superfamily_CUB,HMMSmart_EGF_CA,HMMPfam_Laminin_EGF,HMMSmart_EGF_Lam,PatternScan_EGF_LAM_1,HMMPfam_PSI,HMMSmart_PSI,HMMSmart_EGF,HMMPfam_Kelch_1,superfamily_Gal_oxid_central,PatternScan_EGF_1,PatternScan_EGF_2,HMMPfam_EGF_CA,HMMPfam_EGF_2,PatternScan_EGF_CA,PatternScan_C_TYPE_LECTIN_1,superfamily_SSF57196	-	no_errors	72	10	12.20	48	44	47.31	4	2	33.33
SYNGR4	0	genome.wustl.edu	36	19	53570758	53570758	+	Silent	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	19	53570758	53570758	C	T	SNP	SYNGR4	NM_012451.2	human	genbank	54_36p	+1	reviewed	silent	c.408	p.F136	0.848	HMMPfam_MARVEL	HMMPfam_MARVEL	-	no_errors	591	62	9.47	49	41	45.05	0	1	100.00
CLDN14	0	genome.wustl.edu	36	21	36755479	36755479	+	Missense_Mutation	SNP	C	C	T			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	C	C	C	T	C	C	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	21	36755479	36755479	C	T	SNP	CLDN14	NM_012130.1	human	genbank	54_36p	-1	reviewed	missense	c.385	p.G129S	1.000	HMMPfam_PMP22_Claudin	HMMPfam_PMP22_Claudin,PatternScan_CLAUDIN	-	no_errors	148	10	6.33	53	19	26.39	NA	NA	NA
NPM1	0	genome.wustl.edu	36	5	170770148	170770149	+	Frame_Shift_Ins	INS	-	-	TCTG			TCGA-AB-2810-03B-01W-0728-08	TCGA-AB-2810-11B-01W-0728-08	-	-	-	TCTG	-	-	Verified	Valid	Somatic	Phase_IV	WXS	Hybrid_Capture_Illumina_Seq	1	dbGAP	Illumina HiSeq	0a3cc109-86cf-44a8-abf6-2c244c26656c	933b44ef-cb71-487d-8354-af1e55554415	5	170770148	170770149	-	TCTG	INS	NPM1	NM_002520.1	human	genbank	54_36p	+1	validated	frame_shift_ins	c.859_860	p.W288fs	1.000:1.000	NULL	HMMPfam_Nucleoplasmin,superfamily_Nucleoplasmin-like core domain	-	no_errors	NA	NA	NA	NA	NA	NA	NA	NA	NA