Hugo_Symbol	Entrez_Gene_Id	Center	NCBI_Build	Chromosome	Start_position	End_position	Strand	Variant_Classification	Variant_Type	Reference_Allele	Tumor_Seq_Allele1	Tumor_Seq_Allele2	dbSNP_RS	dbSNP_Val_Status	Tumor_Sample_Barcode	Matched_Norm_Sample_Barcode	Match_Norm_Seq_Allele1	Match_Norm_Seq_Allele2	Tumor_Validation_Allele1	Tumor_Validation_Allele2	Match_Norm_Validation_Allele1	Match_Norm_Validation_Allele2	Verification_Status	Validation_Status	Mutation_Status	Sequencing_Phase	Sequence_Source	Validation_Method	Score	BAM_file	Sequencer	Tumor_Sample_UUID	Matched_Norm_Sample_UUID	Genome_Change	Annotation_Transcript	Transcript_Strand	Transcript_Exon	Transcript_Position	cDNA_Change	Codon_Change	Protein_Change	Other_Transcripts	Refseq_mRNA_Id	Refseq_prot_Id	SwissProt_acc_Id	SwissProt_entry_Id	Description	UniProt_AApos	UniProt_Region	UniProt_Site	UniProt_Natural_Variations	UniProt_Experimental_Info	GO_Biological_Process	GO_Cellular_Component	GO_Molecular_Function	COSMIC_overlapping_mutations	COSMIC_fusion_genes	COSMIC_tissue_types_affected	COSMIC_total_alterations_in_gene	Tumorscape_Amplification_Peaks	Tumorscape_Deletion_Peaks	TCGAscape_Amplification_Peaks	TCGAscape_Deletion_Peaks	DrugBank	ref_context	gc_content	CCLE_ONCOMAP_overlapping_mutations	CCLE_ONCOMAP_total_mutations_in_gene	CGC_Mutation_Type	CGC_Translocation_Partner	CGC_Tumor_Types_Somatic	CGC_Tumor_Types_Germline	CGC_Other_Diseases	DNARepairGenes_Role	FamilialCancerDatabase_Syndromes	MUTSIG_Published_Results	OREGANNO_ID	OREGANNO_Values	t_alt_count	t_ref_count	validation_alt_allele	validation_method	validation_status	validation_tumor_sample	pox	qox	pox_cutoff	isArtifactMode	oxoGCut
NCOA2	10499	broad.mit.edu	37	8	71069384	71069384	+	Missense_Mutation	SNP	G	G	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr8:71069384G>T	ENST00000452400.2	-	11	1397	c.1216C>A	c.(1216-1218)Cag>Aag	p.Q406K		NM_006540.2	NP_006531.1	Q15596	NCOA2_HUMAN	nuclear receptor coactivator 2	406					cellular lipid metabolic process|transcription, DNA-dependent	nucleoplasm	histone acetyltransferase activity|ligand-dependent nuclear receptor binding|nuclear hormone receptor binding|signal transducer activity		PAX3/NCOA2(4)|HEY1/NCOA2(10)	NS(1)|breast(4)|endometrium(7)|kidney(4)|large_intestine(10)|lung(25)|ovary(1)|pancreas(2)|prostate(2)|skin(4)	60	Breast(64;0.201)		Epithelial(68;0.0147)|OV - Ovarian serous cystadenocarcinoma(28;0.0455)|all cancers(69;0.0606)			CACAGGGCCTGATGGGCAGGG	0.498000			T	"""RUNXBP2, HEY1"""	"""AML, Chondrosarcoma"""								6	46					0.00198382	0.00207399	1	1	0
DAPK1	1612	broad.mit.edu	37	9	90321375	90321375	+	Missense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr9:90321375G>A	ENST00000469640.2	+	27	3839	c.3464G>A	c.(3463-3465)cGc>cAc	p.R1155H	DAPK1_ENST00000472284.1_Missense_Mutation_p.R1130H|DAPK1_ENST00000358077.5_Missense_Mutation_p.R1130H|DAPK1_ENST00000491893.1_Missense_Mutation_p.R1064H|DAPK1_ENST00000408954.3_Missense_Mutation_p.R1130H			P53355	DAPK1_HUMAN	death-associated protein kinase 1	1130					apoptosis|induction of apoptosis by extracellular signals|intracellular protein kinase cascade	actin cytoskeleton|cytoplasm	ATP binding|calmodulin binding|protein serine/threonine kinase activity			breast(5)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(27)|liver(2)|lung(17)|ovary(1)|prostate(2)|skin(3)|stomach(1)	72						GGTGGCGTGCGCATCGTGCCC	0.612000									Chronic Lymphocytic Leukemia, Familial Clustering of				3	31					0	0	1	0	0
TMEM63A	9725	broad.mit.edu	37	1	226059715	226059715	+	Nonsense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:226059715G>C	ENST00000366835.3	-	5	575	c.305C>G	c.(304-306)tCa>tGa	p.S102*		NM_014698.2	NP_055513.2	O94886	TM63A_HUMAN	transmembrane protein 63A	102						integral to membrane|lysosomal membrane	nucleotide binding	p.S102*(1)		breast(2)|endometrium(3)|large_intestine(5)|lung(6)|ovary(1)|skin(2)|stomach(1)|upper_aerodigestive_tract(3)|urinary_tract(1)	24	Breast(184;0.197)					TTGTTGACCTGAGGAGGAAGT	0.438000													4	68					0	0	1	0	0
TLR5	7100	broad.mit.edu	37	1	223285772	223285772	+	Missense_Mutation	SNP	A	A	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:223285772A>T	ENST00000540964.1	-	4	1063	c.602T>A	c.(601-603)tTt>tAt	p.F201Y	TLR5_ENST00000342210.6_Missense_Mutation_p.F201Y			O60602	TLR5_HUMAN	toll-like receptor 5	201					cellular response to mechanical stimulus|inflammatory response|innate immune response|MyD88-dependent toll-like receptor signaling pathway|positive regulation of interleukin-8 production|positive regulation of toll-like receptor signaling pathway	integral to membrane|plasma membrane	interleukin-1 receptor binding|transmembrane receptor activity			breast(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(4)|lung(8)|ovary(2)|skin(3)|stomach(2)|upper_aerodigestive_tract(1)|urinary_tract(2)	32				GBM - Glioblastoma multiforme(131;0.0851)		TGCGAGGCTAAAAAAGGAGAG	0.418000													19	92					0	0	1	0	0
SPG11	80208	broad.mit.edu	37	15	44864886	44864886	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr15:44864886G>C	ENST00000261866.7	-	33	6354	c.6338C>G	c.(6337-6339)tCt>tGt	p.S2113C	SPG11_ENST00000535302.2_Missense_Mutation_p.S2000C|SPG11_ENST00000427534.2_Missense_Mutation_p.S2113C	NM_025137.3	NP_079413.3	Q96JI7	SPTCS_HUMAN	spastic paraplegia 11 (autosomal recessive)	2113					cell death	cytosol|integral to membrane|nucleus	protein binding			autonomic_ganglia(1)|breast(5)|central_nervous_system(1)|cervix(1)|endometrium(2)|kidney(4)|large_intestine(16)|lung(24)|ovary(5)|prostate(3)|skin(3)|stomach(2)|upper_aerodigestive_tract(3)|urinary_tract(2)	72		all_cancers(109;1.29e-14)|all_epithelial(112;1.26e-12)|Lung NSC(122;1.34e-07)|all_lung(180;1.21e-06)|Melanoma(134;0.0122)		all cancers(107;2.93e-22)|GBM - Glioblastoma multiforme(94;1.55e-06)|COAD - Colon adenocarcinoma(120;0.0432)|Colorectal(105;0.0484)|Lung(196;0.104)|LUSC - Lung squamous cell carcinoma(244;0.214)		CTTACTGCAAGACAGTTCCCC	0.453000													12	79					0	0	1	0	0
GEMIN4	50628	broad.mit.edu	37	17	650236	650236	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr17:650236G>C	ENST00000576778.1	-	1	2355	c.1014C>G	c.(1012-1014)tgC>tgG	p.C338W	GEMIN4_ENST00000319004.5_Missense_Mutation_p.C349W|GEMIN4_ENST00000437269.1_3'UTR			P57678	GEMI4_HUMAN	gem (nuclear organelle) associated protein 4	349					rRNA processing|spliceosomal snRNP assembly	Cajal body|cytosol|nucleolus|small nuclear ribonucleoprotein complex|spliceosomal complex	protein binding			breast(1)|cervix(1)|endometrium(2)|kidney(3)|large_intestine(4)|lung(4)|ovary(4)|skin(1)|stomach(1)|upper_aerodigestive_tract(1)	22		Myeloproliferative disorder(207;0.204)		UCEC - Uterine corpus endometrioid carcinoma (25;0.022)		TCAGACTGTCGCACAGCCGGT	0.642000													25	78					0	0	1	0	0
AADACL4	343066	broad.mit.edu	37	1	12726598	12726598	+	Missense_Mutation	SNP	G	G	A	rs150325490	by1000genomes	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:12726598G>A	ENST00000376221.1	+	4	1076	c.1076G>A	c.(1075-1077)cGc>cAc	p.R359H		NM_001013630.1	NP_001013652.1	Q5VUY2	ADCL4_HUMAN	arylacetamide deacetylase-like 4	359						integral to membrane	carboxylesterase activity			breast(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(6)|lung(6)|prostate(1)	17	Ovarian(185;0.249)	Renal(390;0.000469)|Lung NSC(185;0.000937)|all_lung(284;0.00122)|Colorectal(325;0.00215)|Breast(348;0.0042)|Myeloproliferative disorder(586;0.0393)|Hepatocellular(190;0.0623)|Ovarian(437;0.0731)		UCEC - Uterine corpus endometrioid carcinoma (279;0.0228)|Colorectal(212;6.81e-07)|COAD - Colon adenocarcinoma(227;0.000274)|BRCA - Breast invasive adenocarcinoma(304;0.000311)|Kidney(185;0.00217)|KIRC - Kidney renal clear cell carcinoma(229;0.00579)|STAD - Stomach adenocarcinoma(313;0.00743)|READ - Rectum adenocarcinoma(331;0.0384)		TATAAGAAGCGCTTGGAGGAC	0.493000													69	155					0	0	1	0	0
KLRG2	346689	broad.mit.edu	37	7	139164979	139164979	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:139164979C>T	ENST00000340940.4	-	2	841	c.772G>A	c.(772-774)Gtg>Atg	p.V258M	KLRG2_ENST00000393039.2_Intron	NM_198508.2	NP_940910.1	A4D1S0	KLRG2_HUMAN	killer cell lectin-like receptor subfamily G, member 2	258						integral to membrane	sugar binding			central_nervous_system(1)|large_intestine(2)|lung(3)	6	Melanoma(164;0.233)					AGGGACTTCACGTACATGGGT	0.567000													7	49					0	0	1	0	0
OSBPL8	114882	broad.mit.edu	37	12	76786408	76786408	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr12:76786408G>C	ENST00000261183.3	-	10	1361	c.882C>G	c.(880-882)ttC>ttG	p.F294L	OSBPL8_ENST00000393250.4_Missense_Mutation_p.F252L|OSBPL8_ENST00000393249.2_Missense_Mutation_p.F252L	NM_020841.4	NP_065892.1	Q9BZF1	OSBL8_HUMAN	oxysterol binding protein-like 8	294					lipid transport		lipid binding			breast(1)|endometrium(3)|kidney(2)|large_intestine(6)|lung(14)|ovary(2)	28						GTAAGCCATAGAAAGTCACAT	0.413000													5	81					0	0	1	0	0
ZNF99	7652	broad.mit.edu	37	19	22940555	22940555	+	Missense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr19:22940555G>A	ENST00000397104.3	-	5	1882	c.1883C>T	c.(1882-1884)aCt>aTt	p.T628I	ZNF99_ENST00000596209.1_Missense_Mutation_p.T719I					zinc finger protein 99									p.T628N(1)		NS(1)|breast(1)|central_nervous_system(3)|endometrium(6)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(20)|lung(55)|ovary(2)|prostate(10)|skin(5)|stomach(9)|upper_aerodigestive_tract(2)|urinary_tract(3)	124		Lung NSC(12;0.0207)|all_lung(12;0.0214)|all_epithelial(12;0.102)				TTTTCTAAGAGTTGAGGACTG	0.358000													17	60					0	0	1	0	0
DEF8	54849	broad.mit.edu	37	16	90025437	90025437	+	Missense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr16:90025437G>A	ENST00000563594.1	+	6	1385	c.388G>A	c.(388-390)Gag>Aag	p.E130K	DEF8_ENST00000268676.7_Missense_Mutation_p.E191K|DEF8_ENST00000418391.2_Missense_Mutation_p.E130K|DEF8_ENST00000570182.1_Missense_Mutation_p.E120K|DEF8_ENST00000563795.1_Missense_Mutation_p.E130K|DEF8_ENST00000569453.1_Missense_Mutation_p.E130K|DEF8_ENST00000563848.1_3'UTR|DEF8_ENST00000567874.1_Missense_Mutation_p.E70K	NM_001242818.1|NM_001242819.1	NP_001229747.1|NP_001229748.1	Q6ZN54	DEFI8_HUMAN	differentially expressed in FDCP 8 homolog (mouse)	191					intracellular signal transduction		zinc ion binding			central_nervous_system(1)|cervix(1)|large_intestine(1)|lung(8)|upper_aerodigestive_tract(1)	12		all_cancers(9;7.59e-13)|Lung NSC(15;1.56e-06)|all_lung(18;2.18e-06)|all_neural(9;0.0019)|all_hematologic(23;0.0194)		BRCA - Breast invasive adenocarcinoma(80;0.0274)		CAATGAGGATGAGCCAAACAT	0.542000													11	153					0	0	1	0	0
MYOC	4653	broad.mit.edu	37	1	171621695	171621695	+	Missense_Mutation	SNP	C	C	A	rs2234925	by1000genomes	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:171621695C>A	ENST00000037502.5	-	1	116	c.57G>T	c.(55-57)caG>caT	p.Q19H		NM_000261.1	NP_000252.1	Q99972	MYOC_HUMAN	myocilin, trabecular meshwork inducible glucocorticoid response	19			Q -> H (in dbSNP:rs2234925).		anatomical structure morphogenesis	cilium|extracellular space|rough endoplasmic reticulum	structural molecule activity			breast(1)|endometrium(2)|haematopoietic_and_lymphoid_tissue(3)|kidney(1)|large_intestine(4)|lung(12)|ovary(2)|prostate(1)|urinary_tract(2)	28	all_cancers(6;5.47e-10)|all_hematologic(923;0.088)|Acute lymphoblastic leukemia(37;0.181)					GAAGCAGCAGCTGGACAGCTG	0.587000													10	38					0.000442599	0.000477177	1	1	0
AGK	55750	broad.mit.edu	37	7	141315327	141315327	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:141315327G>C	ENST00000355413.4	+	8	740	c.480G>C	c.(478-480)ttG>ttC	p.L160F	AGK_ENST00000473247.1_Missense_Mutation_p.L132F|AGK_ENST00000535825.1_Missense_Mutation_p.L157F	NM_018238.3	NP_060708.1	Q53H12	AGK_HUMAN	acylglycerol kinase	160	DAGKc.				activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway	mitochondrial membrane	acylglycerol kinase activity|ATP binding|diacylglycerol kinase activity|NAD+ kinase activity			breast(1)|endometrium(1)|large_intestine(4)|lung(6)|ovary(1)|pancreas(1)|prostate(3)	17	Melanoma(164;0.0171)					CCAGTAGTTTGAGTCATACCC	0.433000													8	196					0	0	1	0	0
CPLX1	10815	broad.mit.edu	37	4	780459	780459	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr4:780459C>T	ENST00000304062.6	-	4	466	c.235G>A	c.(235-237)Gag>Aag	p.E79K	CPLX1_ENST00000505203.1_Missense_Mutation_p.E58K	NM_006651.3	NP_006642.1	O14810	CPLX1_HUMAN	complexin 1	79					glutamate secretion	cytosol				kidney(1)|lung(2)	3				Colorectal(103;0.187)		GCCTCGGCCTCGCGCTCCTCC	0.756000													4	37					0	0	1	0	0
CHRAC1	54108	broad.mit.edu	37	8	141525224	141525224	+	Splice_Site	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr8:141525224G>A	ENST00000220913.5	+	3	476		c.e3-1		CHRAC1_ENST00000519533.1_Splice_Site	NM_017444.5	NP_059140.1	Q9NRG0	CHRC1_HUMAN	chromatin accessibility complex 1						chromatin remodeling	chromatin accessibility complex|epsilon DNA polymerase complex	DNA-directed DNA polymerase activity|sequence-specific DNA binding			ovary(2)	2	all_cancers(97;5.52e-16)|all_epithelial(106;1.22e-13)|Lung NSC(106;4.09e-06)|all_lung(105;6e-06)|Ovarian(258;0.0154)|Acute lymphoblastic leukemia(118;0.155)		BRCA - Breast invasive adenocarcinoma(115;0.107)			ATGTTTTTAAGATATATTACC	0.333000													6	88					0	0	1	0	0
FKBP9	11328	broad.mit.edu	37	7	33020103	33020103	+	Missense_Mutation	SNP	T	T	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:33020103T>G	ENST00000242209.4	+	5	1000	c.831T>G	c.(829-831)agT>agG	p.S277R	FKBP9_ENST00000538443.1_Missense_Mutation_p.S139R|FKBP9_ENST00000490776.2_Missense_Mutation_p.S45R|FKBP9_ENST00000489038.1_3'UTR|AVL9_ENST00000404479.1_Intron|FKBP9_ENST00000538336.1_Missense_Mutation_p.S330R	NM_007270.3	NP_009201.2	O95302	FKBP9_HUMAN	FK506 binding protein 9, 63 kDa	277					protein folding	endoplasmic reticulum|membrane	calcium ion binding|FK506 binding|peptidyl-prolyl cis-trans isomerase activity			central_nervous_system(13)|cervix(1)|endometrium(1)|haematopoietic_and_lymphoid_tissue(1)|kidney(5)|large_intestine(6)|lung(9)|ovary(2)|upper_aerodigestive_tract(1)	39			GBM - Glioblastoma multiforme(11;0.0156)			TAAGTCAAAGTGGGGACTTTC	0.428000													8	176					0	0	1	0	0
UBXN2A	165324	broad.mit.edu	37	2	24194237	24194237	+	Missense_Mutation	SNP	C	C	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr2:24194237C>G	ENST00000309033.4	+	3	377	c.133C>G	c.(133-135)Cag>Gag	p.Q45E	UBXN2A_ENST00000446425.2_3'UTR|UBXN2A_ENST00000535786.1_Missense_Mutation_p.Q45E|UBXN2A_ENST00000404924.1_Missense_Mutation_p.Q45E	NM_181713.3	NP_859064.2	P68543	UBX2A_HUMAN	UBX domain protein 2A	45										endometrium(1)|large_intestine(3)|liver(1)|lung(6)	11						TGAGGAAGCTCAGAAGGTTAG	0.338000													9	110					0	0	1	0	0
HUWE1	10075	broad.mit.edu	37	X	53563554	53563554	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chrX:53563554C>T	ENST00000342160.3	-	78	12669	c.12212G>A	c.(12211-12213)cGa>cAa	p.R4071Q	HUWE1_ENST00000262854.6_Missense_Mutation_p.R4071Q			Q7Z6Z7	HUWE1_HUMAN	HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase	4071	HECT.				base-excision repair|cell differentiation|histone ubiquitination|protein monoubiquitination|protein polyubiquitination|protein ubiquitination involved in ubiquitin-dependent protein catabolic process	cytoplasm|nucleus	DNA binding|protein binding|ubiquitin-protein ligase activity			NS(1)|breast(15)|central_nervous_system(1)|cervix(1)|endometrium(17)|haematopoietic_and_lymphoid_tissue(4)|kidney(8)|large_intestine(29)|liver(2)|lung(52)|ovary(11)|prostate(2)|skin(5)|upper_aerodigestive_tract(3)|urinary_tract(2)	153						AAACATCTCTCGAGAGATGAT	0.483000													6	53					0	0	1	0	0
CEACAM7	1087	broad.mit.edu	37	19	42190921	42190921	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr19:42190921C>T	ENST00000006724.3	-	2	497	c.296G>A	c.(295-297)cGa>cAa	p.R99Q	CEACAM7_ENST00000401731.1_Missense_Mutation_p.R99Q|CEACAM7_ENST00000599715.1_5'UTR|CEACAM7_ENST00000602225.1_Missense_Mutation_p.R99Q|CEACAM7_ENST00000338196.4_Missense_Mutation_p.R99Q	NM_006890.3	NP_008821.1	Q14002	CEAM7_HUMAN	carcinoembryonic antigen-related cell adhesion molecule 7	99	Ig-like V-type.					anchored to membrane|integral to membrane|plasma membrane				breast(1)|endometrium(1)|large_intestine(3)|lung(6)|ovary(2)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	18				OV - Ovarian serous cystadenocarcinoma(3;0.0027)|all cancers(3;0.00979)|Epithelial(262;0.0366)		TATTGTCTCTCGACCGTTGTG	0.433000													11	282					0	0	1	0	0
LOC101927209	101927209	broad.mit.edu	37	1	142713774	142713774	+	RNA	SNP	A	A	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:142713774A>G	ENST00000369381.2	-	0	831																											CTTTTTCCACATTGTCATTTT	0.284000													4	48					0	0	1	0	0
PRDM2	7799	broad.mit.edu	37	1	14106511	14106511	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:14106511C>T	ENST00000235372.7	+	8	3077	c.2221C>T	c.(2221-2223)Ccc>Tcc	p.P741S	PRDM2_ENST00000311066.5_Missense_Mutation_p.P741S|PRDM2_ENST00000505823.1_Intron|PRDM2_ENST00000376048.5_Intron|PRDM2_ENST00000343137.4_Missense_Mutation_p.P540S|PRDM2_ENST00000413440.1_Missense_Mutation_p.P540S|PRDM2_ENST00000503842.1_Intron	NM_012231.4	NP_036363.2	Q13029	PRDM2_HUMAN	PR domain containing 2, with ZNF domain	741						Golgi apparatus|nucleus	DNA binding|histone-lysine N-methyltransferase activity|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(16)|lung(20)|ovary(3)|prostate(3)|skin(1)|urinary_tract(2)	55	Ovarian(185;0.249)	all_lung(284;2.56e-05)|Lung NSC(185;4.94e-05)|Renal(390;0.000147)|Breast(348;0.000162)|Colorectal(325;0.00058)|Ovarian(437;0.00965)|Hepatocellular(190;0.0245)|Myeloproliferative disorder(586;0.0255)	GBM - Glioblastoma multiforme(2;0.00182)	UCEC - Uterine corpus endometrioid carcinoma (279;0.00224)|Colorectal(212;3.23e-08)|BRCA - Breast invasive adenocarcinoma(304;2.16e-05)|COAD - Colon adenocarcinoma(227;2.53e-05)|Kidney(185;0.000762)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.00446)|READ - Rectum adenocarcinoma(331;0.0276)|Lung(427;0.145)		CAGCTCTCCTCCCAGTTCTCC	0.502000													6	132					0	0	1	0	0
POMGNT2	84892	broad.mit.edu	37	3	43121309	43121309	+	Silent	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr3:43121309G>A	ENST00000344697.2	-	2	1960	c.1615C>T	c.(1615-1617)Ctg>Ttg	p.L539L	GTDC2_ENST00000441964.1_Silent_p.L539L	NM_032806.4	NP_116195.2																					TGCAGAGCCAGGATGTAAGGC	0.552000													5	103					0	0	1	0	0
ENPP1	5167	broad.mit.edu	37	6	132181556	132181556	+	Silent	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr6:132181556C>T	ENST00000360971.2	+	8	845	c.825C>T	c.(823-825)atC>atT	p.I275I		NM_006208.2	NP_006199.2	P22413	ENPP1_HUMAN	ectonucleotide pyrophosphatase/phosphodiesterase 1	275	Phosphodiesterase.				3'-phosphoadenosine 5'-phosphosulfate metabolic process|biomineral tissue development|cellular phosphate ion homeostasis|cellular response to insulin stimulus|generation of precursor metabolites and energy|immune response|inorganic diphosphate transport|negative regulation of cell growth|negative regulation of fat cell differentiation|negative regulation of glucose import|negative regulation of glycogen biosynthetic process|negative regulation of insulin receptor signaling pathway|negative regulation of protein autophosphorylation|nucleoside triphosphate catabolic process|phosphate metabolic process|sequestering of triglyceride|water-soluble vitamin metabolic process	basolateral plasma membrane|cell surface|extracellular space|integral to membrane	ATP binding|insulin receptor binding|metal ion binding|nucleic acid binding|nucleoside-triphosphate diphosphatase activity|nucleotide diphosphatase activity|phosphodiesterase I activity|polysaccharide binding|protein homodimerization activity|scavenger receptor activity			autonomic_ganglia(1)|breast(2)|endometrium(1)|kidney(3)|large_intestine(8)|lung(22)|ovary(2)|prostate(2)|skin(3)|upper_aerodigestive_tract(2)	46	Breast(56;0.0505)			GBM - Glioblastoma multiforme(226;0.0216)|OV - Ovarian serous cystadenocarcinoma(155;0.022)	Amifostine(DB01143)|Ribavirin(DB00811)	ATGGCATAATCGACAATAAAA	0.303000													4	13					0	0	1	0	0
BCRP7	100133163	broad.mit.edu	37	22	18844888	18844888	+	RNA	SNP	A	A	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr22:18844888A>G	ENST00000412938.1	+	0	3138																											GCTCACGGAAATACAGCTTCA	0.587000													4	38					0	0	1	0	0
SBNO2	22904	broad.mit.edu	37	19	1123582	1123582	+	Silent	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr19:1123582C>T	ENST00000361757.3	-	7	816	c.579G>A	c.(577-579)gcG>gcA	p.A193A	SBNO2_ENST00000438103.2_Silent_p.A136A|SBNO2_ENST00000587024.1_Silent_p.A193A	NM_014963.2	NP_055778.2	Q9Y2G9	SBNO2_HUMAN	strawberry notch homolog 2 (Drosophila)	193	Poly-Glu.				macrophage activation involved in immune response|negative regulation of transcription, DNA-dependent|regulation of inflammatory response|transcription, DNA-dependent					NS(1)|central_nervous_system(1)|cervix(1)|endometrium(5)|kidney(2)|lung(2)|upper_aerodigestive_tract(1)|urinary_tract(1)	14		Acute lymphoblastic leukemia(61;2.53e-14)|all_hematologic(61;8.18e-10)|Lung NSC(49;7.93e-06)|all_lung(49;1.25e-05)|Breast(49;0.000172)|Hepatocellular(1079;0.137)		UCEC - Uterine corpus endometrioid carcinoma (162;6.64e-05)|OV - Ovarian serous cystadenocarcinoma(105;1.09e-113)|Epithelial(107;3.79e-112)|all cancers(105;1.67e-104)|BRCA - Breast invasive adenocarcinoma(158;0.00136)|STAD - Stomach adenocarcinoma(1328;0.18)		CCAGctcctccgcctcctcct	0.662000													3	20					0	0	1	0	0
PTPN3	5774	broad.mit.edu	37	9	112166752	112166752	+	Silent	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr9:112166752G>A	ENST00000412145.1	-	14	4089	c.1536C>T	c.(1534-1536)agC>agT	p.S512S	PTPN3_ENST00000394827.3_Silent_p.S111S|PTPN3_ENST00000262539.3_Silent_p.S489S|PTPN3_ENST00000446349.1_Silent_p.S467S|PTPN3_ENST00000374541.2_Silent_p.S643S	NM_001145369.1|NM_001145371.1	NP_001138841.1|NP_001138843.1	P26045	PTN3_HUMAN	protein tyrosine phosphatase, non-receptor type 3	643	PDZ.				negative regulation of membrane protein ectodomain proteolysis|negative regulation of mitotic cell cycle	cytoplasm|cytoskeleton|internal side of plasma membrane	ATPase binding|cytoskeletal protein binding|phosphotyrosine binding|protein tyrosine phosphatase activity			breast(1)|endometrium(2)|kidney(2)|large_intestine(8)|liver(1)|lung(14)|ovary(4)|prostate(3)|skin(2)|upper_aerodigestive_tract(3)|urinary_tract(1)	41						GCACCGTCCCGCTTTCGAGGC	0.572000													5	58					0	0	1	0	0
ZXDC	79364	broad.mit.edu	37	3	126189852	126189852	+	Missense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr3:126189852G>A	ENST00000389709.3	-	4	1209	c.1156C>T	c.(1156-1158)Cgg>Tgg	p.R386W	ZXDC_ENST00000336332.5_Missense_Mutation_p.R386W	NM_025112.4	NP_079388.3	Q2QGD7	ZXDC_HUMAN	ZXD family zinc finger C	386					positive regulation of transcription, DNA-dependent	nucleus	C2H2 zinc finger domain binding|identical protein binding|LRR domain binding|nucleic acid binding|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(4)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(2)|lung(9)|ovary(1)	17				GBM - Glioblastoma multiforme(114;0.155)		GTAAACCTCCGGTCATCGTCA	0.458000													12	62					0	0	1	0	0
ATP10B	23120	broad.mit.edu	37	5	159992577	159992577	+	Silent	SNP	G	G	A	rs112214351		TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:159992577G>A	ENST00000327245.5	-	26	5115	c.4269C>T	c.(4267-4269)tcC>tcT	p.S1423S		NM_025153.2	NP_079429.2	O94823	AT10B_HUMAN	ATPase, class V, type 10B	1423					ATP biosynthetic process	integral to membrane	ATP binding|ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism|magnesium ion binding|phospholipid-translocating ATPase activity			NS(2)|autonomic_ganglia(1)|breast(2)|central_nervous_system(2)|endometrium(7)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|liver(2)|lung(37)|ovary(4)|pancreas(1)|prostate(5)|skin(3)|stomach(1)	75	Renal(175;0.00196)	Medulloblastoma(196;0.0377)|all_neural(177;0.121)	Kidney(164;7.83e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000525)			GGTGCTCCCCGGATGAGAGTT	0.557000													25	124					0	0	1	0	0
PRSS3P2	154754	broad.mit.edu	37	7	142480063	142480063	+	RNA	SNP	C	C	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:142480063C>A	ENST00000603901.1	+	0	195					NR_001296.3																						GTCACTGCTACAAGCCGTAAG	0.567000													8	45					3.03874e-20	3.49455e-20	1	1	0
INADL	10207	broad.mit.edu	37	1	62274164	62274164	+	Nonsense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:62274164C>T	ENST00000371158.2	+	14	1759	c.1645C>T	c.(1645-1647)Cag>Tag	p.Q549*	INADL_ENST00000316485.6_Nonsense_Mutation_p.Q549*	NM_176877.2	NP_795352.2	Q8NI35	INADL_HUMAN	InaD-like (Drosophila)	549					intracellular signal transduction|tight junction assembly	apical plasma membrane|perinuclear region of cytoplasm|tight junction	protein binding			breast(3)|endometrium(8)|haematopoietic_and_lymphoid_tissue(1)|kidney(11)|large_intestine(8)|liver(1)|lung(51)|ovary(3)|pancreas(1)|prostate(7)|skin(5)|stomach(1)|upper_aerodigestive_tract(3)	103						TTTGGACACACAGATTGCAGA	0.284000													3	28					0	0	1	0	0
BMS1P20	96610	broad.mit.edu	37	22	22663086	22663086	+	RNA	SNP	T	T	G	rs1054157	by1000genomes	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr22:22663086T>G	ENST00000426066.1	+	0	525					NR_027293.1																						AGCTGCCACATAAGTTGTCCT	0.299000													4	27					0	0	1	0	0
TGFBR2	7048	broad.mit.edu	37	3	30732969	30732969	+	Missense_Mutation	SNP	C	C	T	rs104893810		TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr3:30732969C>T	ENST00000295754.5	+	7	1964	c.1582C>T	c.(1582-1584)Cgt>Tgt	p.R528C	TGFBR2_ENST00000359013.4_Missense_Mutation_p.R553C	NM_003242.5	NP_003233.4	P37173	TGFR2_HUMAN	transforming growth factor, beta receptor II (70/80kDa)	528	Protein kinase.		R -> C (in LDS1B).|R -> H (in LDS1B).		activation of protein kinase activity|brain development|embryonic cranial skeleton morphogenesis|embryonic hemopoiesis|heart development|myeloid dendritic cell differentiation|palate development|pathway-restricted SMAD protein phosphorylation|patterning of blood vessels|peptidyl-serine phosphorylation|peptidyl-threonine phosphorylation|positive regulation of B cell tolerance induction|positive regulation of mesenchymal cell proliferation|positive regulation of NK T cell differentiation|positive regulation of reactive oxygen species metabolic process|positive regulation of T cell tolerance induction|positive regulation of tolerance induction to self antigen|response to cholesterol|response to drug|transforming growth factor beta receptor signaling pathway|vasculogenesis	caveola|external side of plasma membrane	ATP binding|glycosaminoglycan binding|metal ion binding|protein binding|receptor signaling protein serine/threonine kinase activity|SMAD binding|transforming growth factor beta binding|transforming growth factor beta receptor activity, type II|type I transforming growth factor beta receptor binding|type III transforming growth factor beta receptor binding	p.R528C(2)		breast(1)|central_nervous_system(1)|endometrium(2)|kidney(1)|large_intestine(15)|lung(10)|ovary(3)|pancreas(12)|skin(1)|stomach(5)|upper_aerodigestive_tract(2)	53						CCCAGAGGCCCGTCTCACAGC	0.597000													30	46					0	0	1	0	0
TRIO	7204	broad.mit.edu	37	5	14504698	14504698	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:14504698G>C	ENST00000344204.4	+	55	8632	c.8608G>C	c.(8608-8610)Gaa>Caa	p.E2870Q	TRIO_ENST00000344135.5_Missense_Mutation_p.E369Q|TRIO_ENST00000537187.1_Missense_Mutation_p.E2694Q	NM_007118.2	NP_009049.2	O75962	TRIO_HUMAN	trio Rho guanine nucleotide exchange factor	2870	Protein kinase.				apoptosis|axon guidance|induction of apoptosis by extracellular signals|nerve growth factor receptor signaling pathway|regulation of Rho protein signal transduction|small GTPase mediated signal transduction|transmembrane receptor protein tyrosine phosphatase signaling pathway	cytosol	ATP binding|protein serine/threonine kinase activity|Rho guanyl-nucleotide exchange factor activity			NS(2)|breast(6)|central_nervous_system(4)|endometrium(16)|haematopoietic_and_lymphoid_tissue(1)|kidney(7)|large_intestine(21)|lung(34)|ovary(4)|prostate(2)|skin(11)|stomach(3)|upper_aerodigestive_tract(3)|urinary_tract(4)	118	Lung NSC(4;0.000742)					CCTGGTCTTAGAAATGTGCGT	0.562000													11	219					0	0	1	0	0
HSD17B7P2	158160	broad.mit.edu	37	10	38654432	38654432	+	RNA	SNP	A	A	G	rs2257765		TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr10:38654432A>G	ENST00000494540.1	+	0	599					NR_003086.1																						TCATCTCGCAATGCAAGGAAA	0.453000													5	68					0	0	1	0	0
RRN3P2	653390	broad.mit.edu	37	16	29110458	29110458	+	RNA	SNP	T	T	C	rs151074589	by1000genomes	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr16:29110458T>C	ENST00000564580.1	+	0	1131																		p.W375R(25)									GAATTTTGAGTGGATAGTGAT	0.328000													4	47					0	0	1	0	0
TNKS1BP1	85456	broad.mit.edu	37	11	57076681	57076681	+	Silent	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr11:57076681C>T	ENST00000532437.1	-	5	3815	c.3504G>A	c.(3502-3504)agG>agA	p.R1168R	TNKS1BP1_ENST00000358252.3_Silent_p.R1168R			Q9C0C2	TB182_HUMAN	tankyrase 1 binding protein 1, 182kDa	1168	Acidic.|Gly-rich.				nuclear-transcribed mRNA poly(A) tail shortening|telomere maintenance via telomerase	cytoskeleton|cytosol|nuclear telomeric heterochromatin	ankyrin binding|enzyme binding			breast(3)|central_nervous_system(1)|endometrium(5)|haematopoietic_and_lymphoid_tissue(2)|kidney(5)|large_intestine(11)|lung(24)|ovary(3)|prostate(3)|skin(3)|upper_aerodigestive_tract(3)|urinary_tract(1)	64		all_epithelial(135;0.21)				CTTCCAAGTTCCTGAGACCCA	0.607000													5	101					0	0	1	0	0
BMS1P20	96610	broad.mit.edu	37	22	22663087	22663087	+	RNA	SNP	A	A	G	rs1054158		TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr22:22663087A>G	ENST00000426066.1	+	0	526					NR_027293.1																						GCTGCCACATAAGTTGTCCTT	0.303000													4	26					0	0	1	0	0
AFAP1L1	134265	broad.mit.edu	37	5	148687053	148687053	+	Nonsense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:148687053G>A	ENST00000296721.4	+	7	722	c.624G>A	c.(622-624)tgG>tgA	p.W208*	AFAP1L1_ENST00000522492.1_3'UTR|AFAP1L1_ENST00000515000.1_Nonsense_Mutation_p.W208*	NM_001146337.1|NM_152406.2	NP_001139809.1|NP_689619.1	Q8TED9	AF1L1_HUMAN	actin filament associated protein 1-like 1	208							protein binding			breast(1)|endometrium(3)|kidney(1)|large_intestine(6)|liver(1)|lung(10)|ovary(1)|pancreas(1)|skin(2)	26			KIRC - Kidney renal clear cell carcinoma(527;0.00112)|Kidney(363;0.00191)			GACACCAGTGGCCCTCAGAGG	0.592000													8	74					0	0	1	0	0
NOD1	10392	broad.mit.edu	37	7	30486608	30486608	+	Missense_Mutation	SNP	C	C	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:30486608C>T	ENST00000222823.4	-	8	2869	c.2344G>A	c.(2344-2346)Gaa>Aaa	p.E782K		NM_006092.2	NP_006083.1	Q9Y239	NOD1_HUMAN	nucleotide-binding oligomerization domain containing 1	782					activation of MAPK activity|detection of bacterium|induction of apoptosis|inflammatory response|innate immune response|interleukin-8 biosynthetic process|JNK cascade|MyD88-dependent toll-like receptor signaling pathway|MyD88-independent toll-like receptor signaling pathway|positive regulation of dendritic cell antigen processing and presentation|positive regulation of I-kappaB kinase/NF-kappaB cascade|positive regulation of NF-kappaB transcription factor activity|protein oligomerization|stress-activated MAPK cascade|Toll signaling pathway|toll-like receptor 1 signaling pathway|toll-like receptor 2 signaling pathway|toll-like receptor 3 signaling pathway|toll-like receptor 4 signaling pathway	basolateral plasma membrane|cytosol	ATP binding|CARD domain binding|caspase activator activity|peptidoglycan binding|protein homodimerization activity			breast(1)|central_nervous_system(2)|endometrium(6)|haematopoietic_and_lymphoid_tissue(1)|kidney(2)|large_intestine(5)|lung(17)|ovary(2)|prostate(1)|skin(2)	39						CCTTTGCATTCATCCAGGATT	0.453000													7	82					0	0	1	0	0
PRDM2	7799	broad.mit.edu	37	1	14108764	14108764	+	Missense_Mutation	SNP	C	C	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:14108764C>G	ENST00000235372.7	+	8	5330	c.4474C>G	c.(4474-4476)Cat>Gat	p.H1492D	PRDM2_ENST00000311066.5_Missense_Mutation_p.H1492D|PRDM2_ENST00000505823.1_Intron|PRDM2_ENST00000376048.5_Intron|PRDM2_ENST00000343137.4_Missense_Mutation_p.H1291D|PRDM2_ENST00000413440.1_Missense_Mutation_p.H1291D|PRDM2_ENST00000503842.1_Intron	NM_012231.4	NP_036363.2	Q13029	PRDM2_HUMAN	PR domain containing 2, with ZNF domain	1492						Golgi apparatus|nucleus	DNA binding|histone-lysine N-methyltransferase activity|sequence-specific DNA binding transcription factor activity|zinc ion binding			endometrium(9)|haematopoietic_and_lymphoid_tissue(1)|large_intestine(16)|lung(20)|ovary(3)|prostate(3)|skin(1)|urinary_tract(2)	55	Ovarian(185;0.249)	all_lung(284;2.56e-05)|Lung NSC(185;4.94e-05)|Renal(390;0.000147)|Breast(348;0.000162)|Colorectal(325;0.00058)|Ovarian(437;0.00965)|Hepatocellular(190;0.0245)|Myeloproliferative disorder(586;0.0255)	GBM - Glioblastoma multiforme(2;0.00182)	UCEC - Uterine corpus endometrioid carcinoma (279;0.00224)|Colorectal(212;3.23e-08)|BRCA - Breast invasive adenocarcinoma(304;2.16e-05)|COAD - Colon adenocarcinoma(227;2.53e-05)|Kidney(185;0.000762)|KIRC - Kidney renal clear cell carcinoma(229;0.00258)|STAD - Stomach adenocarcinoma(313;0.00446)|READ - Rectum adenocarcinoma(331;0.0276)|Lung(427;0.145)		AAAAGTTTCTCATTCATCTAA	0.443000													11	339					0	0	1	0	0
SDK1	221935	broad.mit.edu	37	7	4304762	4304762	+	Missense_Mutation	SNP	G	G	A			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr7:4304762G>A	ENST00000404826.2	+	45	6527	c.6388G>A	c.(6388-6390)Gac>Aac	p.D2130N	SDK1_ENST00000389531.3_Missense_Mutation_p.D2110N|SDK1_ENST00000466611.1_3'UTR	NM_152744.3	NP_689957.3	Q7Z5N4	SDK1_HUMAN	sidekick cell adhesion molecule 1	2130					cell adhesion	integral to membrane				NS(1)|breast(6)|central_nervous_system(3)|cervix(1)|endometrium(13)|haematopoietic_and_lymphoid_tissue(1)|kidney(8)|large_intestine(42)|lung(55)|ovary(4)|pancreas(1)|prostate(4)|skin(6)|upper_aerodigestive_tract(4)|urinary_tract(4)	153		all_cancers(1;0.127)|Ovarian(82;0.0177)|Myeloproliferative disorder(862;0.194)		UCEC - Uterine corpus endometrioid carcinoma (126;0.121)|OV - Ovarian serous cystadenocarcinoma(56;9.65e-15)		GCAGGCCACGGACTCTGACTA	0.687000													3	22					0	0	1	0	0
ASXL1	171023	broad.mit.edu	37	20	31023282	31023282	+	Missense_Mutation	SNP	G	G	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr20:31023282G>C	ENST00000375687.4	+	13	3191	c.2767G>C	c.(2767-2769)Gag>Cag	p.E923Q	ASXL1_ENST00000306058.5_Missense_Mutation_p.E918Q	NM_015338.5	NP_056153.2	Q8IXJ9	ASXL1_HUMAN	additional sex combs like 1 (Drosophila)	923					chromatin modification|regulation of transcription, DNA-dependent|transcription, DNA-dependent	PR-DUB complex	metal ion binding|protein binding			NS(1)|breast(2)|central_nervous_system(3)|endometrium(2)|haematopoietic_and_lymphoid_tissue(655)|kidney(5)|large_intestine(18)|liver(1)|lung(27)|ovary(1)|prostate(3)|skin(3)|upper_aerodigestive_tract(1)	722						ACCATCTGTTGAGCCCCAGGT	0.512000			"""F, N, Mis"""		"""MDS, CMML"""								4	68					0	0	1	0	0
PSD4	23550	broad.mit.edu	37	2	113955408	113955408	+	Missense_Mutation	SNP	A	A	C			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr2:113955408A>C	ENST00000245796.6	+	14	2737	c.2542A>C	c.(2542-2544)Acc>Ccc	p.T848P	PSD4_ENST00000441564.2_Missense_Mutation_p.T819P	NM_012455.2	NP_036587.2	Q8NDX1	PSD4_HUMAN	pleckstrin and Sec7 domain containing 4	848	PH.				regulation of ARF protein signal transduction	cytoplasm|plasma membrane	ARF guanyl-nucleotide exchange factor activity			cervix(1)|endometrium(2)|large_intestine(4)|lung(13)|ovary(4)|skin(2)|stomach(1)|upper_aerodigestive_tract(1)|urinary_tract(1)	29						CTCGCTGGCCACCCCCGCCAC	0.657000													7	19					0	0	1	0	0
GOLGA2P5	55592	broad.mit.edu	37	12	100559710	100559710	+	RNA	SNP	T	T	G			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr12:100559710T>G	ENST00000397112.4	-	0	599					NR_036632.1															large_intestine(1)|lung(3)	4						CAGAGGCTGGTGCCCGCCTTC	0.602000													6	26					0	0	1	0	0
CD1E	913	broad.mit.edu	37	1	158324402	158324402	+	Missense_Mutation	SNP	G	G	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr1:158324402G>T	ENST00000368160.3	+	2	294	c.294G>T	c.(292-294)caG>caT	p.Q98H	CD1E_ENST00000368161.3_Missense_Mutation_p.Q98H|CD1E_ENST00000368164.3_Intron|CD1E_ENST00000368156.1_Missense_Mutation_p.Q98H|CD1E_ENST00000368155.3_Missense_Mutation_p.Q98H|CD1E_ENST00000444681.2_Intron|CD1E_ENST00000368163.3_Missense_Mutation_p.Q98H|CD1E_ENST00000368154.1_Intron|CD1E_ENST00000368165.3_Missense_Mutation_p.Q98H|CD1E_ENST00000368157.1_Intron|CD1E_ENST00000464822.1_Intron|CD1E_ENST00000368166.3_Intron|CD1E_ENST00000452291.2_Intron|CD1E_ENST00000368167.3_Missense_Mutation_p.Q98H|CD1E_ENST00000434258.1_Missense_Mutation_p.Q96H	NM_001042583.2	NP_001036048.1	P15812	CD1E_HUMAN	CD1e molecule	98					antigen processing and presentation|immune response	early endosome|Golgi membrane|integral to plasma membrane|late endosome|lysosomal lumen				breast(2)|endometrium(2)|kidney(1)|large_intestine(6)|lung(27)|pancreas(1)|prostate(4)|skin(4)|stomach(1)|urinary_tract(1)	49	all_hematologic(112;0.0378)					CACTGTTCCAGTTATACTTCC	0.458000													4	63					1	1	1	1	0
BTNL8	79908	broad.mit.edu	37	5	180335804	180335804	+	Missense_Mutation	SNP	G	G	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:180335804G>T	ENST00000231229.4	+	2	502	c.268G>T	c.(268-270)Gat>Tat	p.D90Y	BTNL8_ENST00000340184.4_Missense_Mutation_p.D90Y|BTNL8_ENST00000400707.3_Intron|BTNL8_ENST00000511704.1_Intron|BTNL8_ENST00000508408.1_Missense_Mutation_p.D90Y	NM_001159708.1|NM_024850.2	NP_001153180.1|NP_079126.1	Q6UX41	BTNL8_HUMAN	butyrophilin-like 8	90	Ig-like V-type 1.					integral to membrane				breast(1)|endometrium(4)|kidney(2)|large_intestine(4)|lung(12)|prostate(3)|skin(1)|upper_aerodigestive_tract(1)	28	all_cancers(89;3.37e-05)|all_epithelial(37;3.77e-06)|Renal(175;0.000159)|Lung NSC(126;0.00211)|all_lung(126;0.00371)|Breast(19;0.114)	all_cancers(40;0.0801)|Medulloblastoma(196;0.0392)|all_neural(177;0.0529)|all_hematologic(541;0.191)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)			ACTGGTGAAGGATTCTATTGC	0.527000													9	237					0.000274275	0.000300397	1	1	0
PIK3R1	5295	broad.mit.edu	37	5	67591125	67591129	+	Frame_Shift_Del	DEL	TGAGA	TGAGA	-			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:67591125_67591129delTGAGA	ENST00000521381.1	+	13	2334_2338	c.1718_1722delTGAGA	c.(1717-1722)cfs	p.LR573fs	PIK3R1_ENST00000274335.5_Frame_Shift_Del_p.LR573fs|PIK3R1_ENST00000396611.1_Frame_Shift_Del_p.LR573fs|PIK3R1_ENST00000523872.1_Frame_Shift_Del_p.LR210fs|PIK3R1_ENST00000320694.8_Frame_Shift_Del_p.LR273fs|PIK3R1_ENST00000521657.1_Frame_Shift_Del_p.LR573fs|PIK3R1_ENST00000336483.5_Frame_Shift_Del_p.LR303fs	NM_181523.2	NP_852664.1	P27986	P85A_HUMAN	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	573					epidermal growth factor receptor signaling pathway|fibroblast growth factor receptor signaling pathway|growth hormone receptor signaling pathway|insulin receptor signaling pathway|insulin-like growth factor receptor signaling pathway|interspecies interaction between organisms|leukocyte migration|nerve growth factor receptor signaling pathway|phosphatidylinositol 3-kinase cascade|phosphatidylinositol phosphorylation|phosphatidylinositol-mediated signaling|platelet activation|positive regulation of establishment of protein localization in plasma membrane|positive regulation of glucose import|T cell costimulation|T cell receptor signaling pathway	1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex	1-phosphatidylinositol binding|ErbB-3 class receptor binding|insulin binding|insulin receptor binding|insulin receptor substrate binding|insulin-like growth factor receptor binding|phosphatidylinositol 3-kinase regulator activity|protein phosphatase binding	p.L573P(2)|p.L303P(2)|p.R574T(2)|p.R574_T576del(2)|p.L273P(2)|p.L570_D578del(1)|p.R574fs*27(1)|p.0?(1)|p.?(1)|p.R574I(1)		breast(12)|central_nervous_system(31)|cervix(1)|endometrium(68)|haematopoietic_and_lymphoid_tissue(5)|kidney(1)|large_intestine(32)|lung(10)|ovary(9)|pancreas(1)|prostate(2)|skin(1)|upper_aerodigestive_tract(3)|urinary_tract(2)	178		Lung NSC(167;1.99e-05)|Prostate(74;0.00308)|Ovarian(174;0.00473)|Colorectal(97;0.0176)		OV - Ovarian serous cystadenocarcinoma(47;3.76e-51)|Lung(70;0.0211)	Isoproterenol(DB01064)	CTTATCCAGCTGAGAAAGACGAGAG	0.380			"""Mis, F, O"""		"""gliobastoma, ovarian, colorectal"""					TCGA GBM(4;<1E-08)			16	120	---	---	---	---					
TRIM7	81786	broad.mit.edu	37	5	180631987	180631987	+	Frame_Shift_Del	DEL	C	C	-			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr5:180631987delC	ENST00000274773.7	-	1	185	c.124delG	c.(124-126)tcfs	p.V42fs	TRIM7_ENST00000334421.5_Frame_Shift_Del_p.V42fs	NM_203293.1	NP_976038.1	Q9C029	TRIM7_HUMAN	tripartite motif containing 7	42						cytoplasm|nucleus	zinc ion binding			NS(1)|cervix(1)|endometrium(2)|large_intestine(3)|lung(6)|ovary(2)|skin(1)|stomach(1)	17	all_cancers(89;6.03e-06)|all_epithelial(37;7.1e-07)|Renal(175;0.000159)|Lung NSC(126;0.00354)|all_lung(126;0.00609)|Breast(19;0.0684)	all_cancers(40;0.000172)|Medulloblastoma(196;0.0133)|all_neural(177;0.0199)|all_lung(500;0.0221)|all_hematologic(541;0.0433)|Lung NSC(249;0.132)|Ovarian(839;0.238)	Kidney(164;2.23e-05)|KIRC - Kidney renal clear cell carcinoma(164;0.000178)	all cancers(165;2e-06)|Epithelial(171;1.35e-05)|OV - Ovarian serous cystadenocarcinoma(192;0.000128)|Kidney(146;0.0674)|GBM - Glioblastoma multiforme(465;0.0802)		CCGCACTCGACGGACACCGGC	0.746													2	4	---	---	---	---					
CLIP1	6249	broad.mit.edu	37	12	122812690	122812691	+	Frame_Shift_Ins	INS	-	-	T			TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr12:122812690_122812691insT	ENST00000358808.2	-	16	3173_3174	c.3019_3020insA	c.(3019-3021)ccafs	p.P1007fs	CLIP1_ENST00000540338.1_Frame_Shift_Ins_p.P1018fs|CLIP1_ENST00000537178.1_Frame_Shift_Ins_p.P972fs|CLIP1_ENST00000361654.4_Frame_Shift_Ins_p.P896fs|CLIP1_ENST00000302528.7_Frame_Shift_Ins_p.P1007fs|CLIP1_ENST00000545889.1_Frame_Shift_Ins_p.P593fs	NM_001247997.1|NM_002956.2	NP_001234926.1|NP_002947.1	P30622	CLIP1_HUMAN	CAP-GLY domain containing linker protein 1	1018					mitotic prometaphase|positive regulation of microtubule polymerization	centrosome|cytosol|endosome|intermediate filament|kinetochore	nucleic acid binding|protein homodimerization activity|zinc ion binding			NS(1)|breast(5)|endometrium(4)|kidney(5)|large_intestine(16)|liver(1)|lung(21)|ovary(2)|prostate(3)|upper_aerodigestive_tract(1)|urinary_tract(1)	60	all_neural(191;0.0837)|Medulloblastoma(191;0.163)			OV - Ovarian serous cystadenocarcinoma(86;1.81e-05)|Epithelial(86;6.85e-05)|BRCA - Breast invasive adenocarcinoma(302;0.226)		CTGGTTGTGGCTTGTTTCCATT	0.505													8	252	---	---	---	---					
EP400	57634	broad.mit.edu	37	12	132547135	132547136	+	In_Frame_Ins	INS	-	-	CAG	rs144787206	byFrequency	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr12:132547135_132547136insCAG	ENST00000333577.4	+	48	8440_8441	c.8331_8332insCAG	c.(8329-8334)caaaca>caCAGaaca	p.2777_2777Q>HR	EP400_ENST00000332482.4_In_Frame_Ins_p.2704_2704Q>HR|EP400_ENST00000389562.2_In_Frame_Ins_p.2740_2740Q>HR|EP400_ENST00000330386.6_In_Frame_Ins_p.2660_2660Q>HR|EP400_ENST00000389561.2_In_Frame_Ins_p.2741_2741Q>HR			Q96L91	EP400_HUMAN	E1A binding protein p400	2777	Interaction with ZNF42 (By similarity).|Poly-Gln.				histone H2A acetylation|histone H4 acetylation|regulation of transcription, DNA-dependent	NuA4 histone acetyltransferase complex|nuclear speck	ATP binding|DNA binding|helicase activity			NS(1)|breast(6)|central_nervous_system(10)|cervix(1)|endometrium(21)|kidney(13)|large_intestine(25)|lung(56)|ovary(5)|prostate(8)|skin(6)|stomach(4)|upper_aerodigestive_tract(2)|urinary_tract(3)	161	all_neural(191;0.0982)|Medulloblastoma(191;0.163)	all_epithelial(31;0.198)		OV - Ovarian serous cystadenocarcinoma(86;3.01e-08)|Epithelial(86;3.43e-07)|all cancers(50;2.01e-06)		agcagcagcagcaacagcagca	0.589													14	61	---	---	---	---					
VEZF1	7716	broad.mit.edu	37	17	56056605	56056607	+	In_Frame_Del	DEL	TGC	TGC	-	rs61731354	byFrequency	TCGA-DQ-7596-01A-11D-2229-08	TCGA-DQ-7596-10D-01D-2229-08								Untested	Somatic	Phase_I	WXS	none			Illumina GAIIx	012bfacf-0f67-4284-aab9-9898b621dc48	27a98375-2c5a-4e54-91b4-a7cd6c74f9e1	g.chr17:56056605_56056607delTGC	ENST00000584396.1	-	5	1105_1107	c.1017_1019delGCA	c.(1015-1020)caa>ca	p.QQ343del	VEZF1_ENST00000581208.1_In_Frame_Del_p.QQ352del			Q14119	VEZF1_HUMAN	vascular endothelial zinc finger 1	352	Poly-Gln.				cellular defense response|regulation of transcription from RNA polymerase II promoter|transcription from RNA polymerase II promoter	nucleus	DNA binding|zinc ion binding			breast(1)|endometrium(1)|kidney(2)|lung(5)|ovary(1)	10						ttgttgttgttgctgctgctgct	0.463													14	311	---	---	---	---