Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_position End_position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID COSMIC_Codon COSMIC_Gene Transcript_Id Exon ChromChange AAChange Genome_Plus_Minus_10_Bp Drug_Target TTotCov_SOL TVarCov_SOL NTotCov_SOL NVarCov_SOL dbSNPPopFreq COSMIC_Gene_Freq HTATSF1 27336 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 X 135593803 135593803 + Frame_Shift_Del DEL A A - novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001163280 exon10 c.1898delC p.T633fs GGATACATATGAA . 65 17 118 0 . . SELP 6403 hgsc.bcm.edu 37 1 169564103 169564103 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 SELP,NS,carcinoma,0,1 SELP NM_003005 exon13 c.C2114A p.S705X AGTTCTGAGCATT . 35 2 107 0 . 0 ITK 3702 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 5 156670696 156670696 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_005546 exon12 c.G1124T p.G375V AATTTGGGTTGGT . 53 19 68 0 . . MYBL2 4605 hgsc.bcm.edu 37 20 42315650 42315650 + Silent SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 MYBL2,NS,carcinoma,0,1 MYBL2 NM_002466 exon5 c.C438A p.I146I CATCATCTGCGAG . 40 2 59 0 . 0 TTC8 123016 hgsc.bcm.edu 37 14 89338781 89338781 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 TTC8,colon,carcinoma,0,1 TTC8 NM_144596 exon13 c.G1332T p.K444N GCGGAAGGGCCAC . 44 2 77 0 . 0 SNX13 23161 hgsc.bcm.edu 37 7 17836491 17836491 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 SNX13,caecum,carcinoma,0,1 SNX13 NM_015132 exon25 c.C2585A p.T862K ACTCTTGTTCTCA . 43 2 91 0 . 0 HSD17B7 51478 hgsc.bcm.edu 37 1 162769603 162769603 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 HSD17B7,NS,carcinoma,0,5 HSD17B7 NM_016371 exon5 c.G518A p.S173N CTCGCAGTGCAAG . 25 2 72 0 . 0 FOLH1 2346 hgsc.bcm.edu 37 11 49175427 49175427 + Silent SNP A A G rs199517010 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 FOLH1,mouth,carcinoma,0,1 FOLH1 NM_004476 exon17 c.T1941C p.S647S TCTCTCACTGAAC . 50 2 68 0 0.001 0 ERMP1 79956 hgsc.bcm.edu 37 9 5825098 5825098 + Silent SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_024896 exon3 c.C762A p.V254V TTGCAAGACATTT . 71 4 126 0 . . OR2L8 391190 hgsc.bcm.edu 37 1 248112794 248112794 + Missense_Mutation SNP G G C rs200574966 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 OR2L8,NS,carcinoma,0,2 OR2L8 NM_001001963 exon1 c.G635C p.G212A TCATTGGTATTTC . 42 2 90 1 . 0 ARHGEF40 55701 hgsc.bcm.edu 37 14 21542360 21542360 + Silent SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ARHGEF40_ENST00000298694,colon,carcinoma,+1,1 ARHGEF40_ENST00000298694 NM_018071 exon3 c.G471A p.R157R GGACCGGCCAACA . 39 2 53 0 . +1 TP53 7157 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 17 7577539 7577539 + Missense_Mutation SNP G G A rs121912651 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 TP53_ENST00000545858,NS,adenocarcinoma,+1,704 TP53_ENST00000545858 NM_000546 exon7 c.C742T p.R248W GCCTCCGGTTCAT . 10 5 48 0 . +1 SLC22A5 6584 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 5 131729481 131729481 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_003060 exon9 c.G1564A p.D522N ACCATTGACCAGA . 31 5 59 0 . . PDE7B 27115 hgsc.bcm.edu 37 6 136512843 136512843 + Silent SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 PDE7B,NS,malignant_melanoma,+2,1 PDE7B NM_018945 exon13 c.C1218A p.L406L CCACCTCGCACAC . 32 2 59 0 . +2 ZMPSTE24 10269 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 1 40724003 40724003 + Silent SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_005857 exon1 c.C60T p.F20F TATCTTCGGGGCC . 32 5 26 0 . . ABCB5 340273 hgsc.bcm.edu 37 7 20778674 20778674 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ABCB5_ENST00000404938,right_upper_lobe,carcinoma,0,2 ABCB5_ENST00000404938 NM_001163941 exon24 c.C2936A p.S979Y AATATTCCAAAGC . 53 3 75 0 . 0 TUBGCP3 10426 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 13 113200144 113200144 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 TUBGCP3,NS,carcinoma,0,2 TUBGCP3 NM_006322 exon11 c.G1204A p.A402T TGTAGGCGTGGAC . 29 4 48 0 . 0 HAUS4 54930 hgsc.bcm.edu 37 14 23424312 23424312 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 HAUS4,NS,carcinoma,0,1 HAUS4 NM_001166270 exon2 c.C52A p.Q18K TACCTTGTTGAAG . 47 3 54 0 . 0 PTCHD1 139411 hgsc.bcm.edu;bcgsc.ca 37 X 23411591 23411591 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_173495 exon3 c.G1956T p.K652N GGCCAAGACCATG . 75 4 114 0 . . STAG2 10735 hgsc.bcm.edu 37 X 123220534 123220534 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001042749 exon30 c.G3191A p.S1064N GAATCAGCAGCCG . 80 4 92 0 . . KRTAP5-5 439915 hgsc.bcm.edu 37 11 1651251 1651251 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 KRTAP5-5,NS,carcinoma,0,2 KRTAP5-5 NM_001001480 exon1 c.G181A p.G61S GGCTCCGGCTGCT . 38 2 77 1 . 0 HEG1 57493 hgsc.bcm.edu 37 3 124732804 124732804 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 HEG1,colon,carcinoma,0,1 HEG1 NM_020733 exon6 c.G1619A p.G540D GCTGTGCCACGCA . 28 2 48 0 . 0 ANKRD34A 284615 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 1 145473924 145473924 + Missense_Mutation SNP T T G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 T T . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001039888 exon4 c.T596G p.M199R GTGGGATGTTATC . 28 7 50 0 . . WASF1 8936 hgsc.bcm.edu 37 6 110423269 110423269 + Silent SNP A A G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 WASF1,colon,carcinoma,0,1 WASF1 NM_001024935 exon9 c.T1044C p.P348P AGGGGGAGGAGTT . 22 4 32 1 . 0 LRRC9 341883 hgsc.bcm.edu;bcgsc.ca 37 14 60398337 60398337 + RNA SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . TTTTAGGGTTTGC . 87 4 130 0 . . DAGLB 221955 hgsc.bcm.edu;bcgsc.ca 37 7 6487440 6487440 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_139179 exon1 c.G34A p.A12T CGATGGCCCAGCG . 75 4 96 0 . . CALN1 83698 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 7 71868298 71868298 + Silent SNP G G A rs376303075 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_031468 exon2 c.C57T p.D19D TCCTCCGTCCCCC . 97 35 156 0 . . MCAM 4162 hgsc.bcm.edu 37 11 119181068 119181068 + Silent SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 MCAM,caecum,carcinoma,0,1 MCAM NM_006500 exon15 c.G1902A p.P634P GTCTCCCGGAGCC . 42 2 54 0 . 0 DNAJC11 55735 hgsc.bcm.edu;ucsc.edu;bcgsc.ca 37 1 6713011 6713011 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_018198 exon6 c.G508A p.A170T AGGGTGCCTAAAA . 34 4 58 0 . . PTMA 5757 hgsc.bcm.edu 37 2 232577559 232577559 + Missense_Mutation SNP T T C novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 T T . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 PTMA,NS,carcinoma,0,2 PTMA NM_001099285 exon5 c.T334C p.X112Q GATGACTAGACAG . 45 2 86 1 . 0 CEACAM5 1048 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 19 42222257 42222257 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_004363 exon6 c.C1448T p.A483V ACTCAGCCAGTGG . 33 4 59 0 . . FLNA 2316 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 X 153595859 153595859 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001456 exon5 c.G774T p.M258I GTAGGTCATGACA . 87 22 114 0 . . ZP4 57829 hgsc.bcm.edu;broad.mit.edu 37 1 238048735 238048735 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ZP4,right_lower_lobe,carcinoma,0,1 ZP4 NM_021186 exon8 c.C1116A p.S372R GTCAGTGCTGGGT . 42 3 68 0 . 0 C7orf33 202865 hgsc.bcm.edu 37 7 148288051 148288051 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 C7orf33,colon,carcinoma,0,1 C7orf33 NM_145304 exon1 c.G34T p.E12X CTTGAAGAGTGTC . 37 2 73 0 . 0 CADPS 8618 hgsc.bcm.edu 37 3 62477973 62477973 + Missense_Mutation SNP C C T rs376315928 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 CADPS_ENST00000383710,NS,carcinoma,0,2 CADPS_ENST00000383710 NM_183394 exon19 c.G2906A p.R969H TCAGTACGGAGAA . 37 2 72 0 . 0 IQCK 124152 hgsc.bcm.edu 37 16 19745076 19745076 + Silent SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 IQCK,colon,carcinoma,0,1 IQCK NM_153208 exon4 c.G303T p.P101P TTTTCCGGTTTCC . 52 3 88 0 . 0 CCDC136 64753 hgsc.bcm.edu 37 7 128446399 128446399 + Silent SNP C C A rs368845976 alternate_allele TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 CCDC136,NS,carcinoma,0,1 CCDC136 NM_022742 exon8 c.C1198A p.R400R GAGCTCCGGCAGC . 16 2 27 0 . 0 ATAD3A 55210 hgsc.bcm.edu;broad.mit.edu 37 1 1458913 1458913 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_018188 exon9 c.G1073A p.R358Q TCAGTCGACCCCA . 55 4 95 0 . . RBMXL3 139804 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 X 114426604 114426604 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001145346 exon1 c.G2600A p.R867H GAGGCCGCTCGCA . 82 20 115 0 . . MLL3 58508 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 7 151891214 151891214 + Splice_Site SNP C C G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 MLL3_ENST00000355193,bladder,carcinoma,0,2 MLL3_ENST00000355193 NM_170606 exon32 c.4541-1G>C . CAAGCTCTAGGAG . 50 9 88 0 . 0 ELMO1 9844 hgsc.bcm.edu 37 7 36910057 36910057 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ELMO1,NS,carcinoma,0,2 ELMO1 NM_014800 exon20 c.G1846T p.V616L TCACCACGGCTTT . 42 2 38 0 . 0 NSUN5 55695 hgsc.bcm.edu;bcgsc.ca 37 7 72722459 72722459 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_148956 exon2 c.C185A p.A62E TTCTCCGCACGGA . 46 4 70 0 . . WWOX 51741 hgsc.bcm.edu 37 16 78420808 78420808 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 WWOX_ENST00000408984,NS,carcinoma,0,3 WWOX_ENST00000408984 NM_016373 exon6 c.G568T p.V190L CGTAGCGTGCAGC . 28 2 32 0 . 0 ANKRD16 54522 hgsc.bcm.edu 37 10 5925099 5925099 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ANKRD16,caecum,carcinoma,0,1 ANKRD16 NM_001009943 exon5 c.C719T p.A240V GCCTGGGCACCCA . 16 2 16 0 . 0 GABRA1 2554 hgsc.bcm.edu 37 5 161324315 161324315 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 GABRA1,NS,carcinoma,0,1 GABRA1 NM_001127643 exon11 c.G1258T p.D420Y AAAATTGACCGAC . 41 3 67 0 . 0 ZNF334 55713 hgsc.bcm.edu 37 20 45130856 45130856 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ZNF334,NS,carcinoma,0,1 ZNF334 NM_018102 exon5 c.G1122T p.E374D TGGCTTCTCTCCT . 38 2 51 0 . 0 KDM2B 84678 hgsc.bcm.edu 37 12 121881589 121881589 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 KDM2B_ENST00000377071,rectum,carcinoma,0,2 KDM2B_ENST00000377071 NM_032590 exon17 c.C2459T p.S820L TGAAGCGATGAGG . 24 2 44 0 . 0 EFCAB5 374786 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 17 28268848 28268848 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_198529 exon1 c.C34A p.P12T CTCAGACCTGCTC . 30 7 55 0 . . COX2 5743 hgsc.bcm.edu;bcgsc.ca 37 MT 7827 7827 + Missense_Mutation SNP T T C novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 T T . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . ENST00000361739 exon1 c.T242C p.L81P CATCCCTACGCAT . 437 51 2160 2 . . ERMP1 79956 hgsc.bcm.edu 37 9 5810057 5810057 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ERMP1,colon,carcinoma,0,1 ERMP1 NM_024896 exon8 c.C1502A p.A501D ATTTTGGCTACAG . 38 2 64 1 . 0 OTUD6B 51633 hgsc.bcm.edu 37 8 92096314 92096314 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 OTUD6B,colon,carcinoma,0,2 OTUD6B NM_016023 exon6 c.G859T p.E287X GGTGAAGAATATT . 49 2 68 0 . 0 MIR548G 100313938 hgsc.bcm.edu 37 3 99524505 99524505 + RNA SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . AAGCAGCCAGGCC . 21 4 18 0 . . RAN 5901 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 12 131359125 131359125 + Silent SNP G G A rs1802283 alternate_allele TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 RAN,NS,carcinoma,0,1 RAN NM_006325 exon5 c.G282A p.S94S AACATCGAGAGTT . 38 13 95 1 . 0 NOTCH3 4854 hgsc.bcm.edu 37 19 15272347 15272347 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 NOTCH3_ENST00000263388,NS,carcinoma,0,2 NOTCH3_ENST00000263388 NM_000435 exon33 c.G6092A p.R2031H GGGCTGCGGGGCC . 15 2 16 0 . 0 EML5 161436 hgsc.bcm.edu 37 14 89171303 89171303 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_183387 exon13 c.C1952A p.P651H AGCTGAGGTAGAT . 60 4 79 0 . . NAA35 60560 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 9 88631517 88631517 + Missense_Mutation SNP A A T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_024635 exon18 c.A1632T p.Q544H CTCTCAAATGGCA . 27 18 60 0 . . CAST 831 hgsc.bcm.edu 37 5 96073607 96073607 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 CAST,NS,carcinoma,0,1 CAST NM_001042440 exon9 c.G631T p.E211X CCTGAAGAAACTG . 39 2 67 0 . 0 BACE1 23621 hgsc.bcm.edu 37 11 117186290 117186290 + Silent SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 BACE1,right_upper_lobe,carcinoma,0,1 BACE1 NM_138972 exon1 c.C222A p.G74G GTAGTAGCCCTGC . 56 3 84 0 . 0 SYT9 143425 hgsc.bcm.edu 37 11 7334708 7334708 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 .,1 . NM_175733 exon3 c.G580T p.G194X TTGACTGGAATTG . 47 2 60 0 . 91 SLC25A17 10478 hgsc.bcm.edu 37 22 41173096 41173096 + Missense_Mutation SNP G G A rs371543259 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 SLC25A17,caecum,carcinoma,0,1 SLC25A17 NM_006358 exon7 c.C641T p.A214V GCAATCGCTTTGG . 40 2 41 0 . 0 KIAA0368 23392 hgsc.bcm.edu 37 9 114133913 114133913 + Silent SNP C C T rs372133962 alternate_allele TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 KIAA0368,NS,carcinoma,0,1 KIAA0368 NM_001080398 exon44 c.G5259A p.T1753T TGCCCACGTTCTT . 44 2 81 0 . 0 RNF38 152006 hgsc.bcm.edu 37 9 36376031 36376031 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 RNF38,NS,carcinoma,0,1 RNF38 NM_022781 exon3 c.C256A p.P86T CCCATGGTCGCAT . 45 2 92 0 . 0 CDH7 1005 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 18 63511084 63511084 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_004361 exon7 c.C1018T p.R340W ACGCTACGGATAG . 43 16 60 0 . . C9orf135 138255 hgsc.bcm.edu;bcgsc.ca 37 9 72501779 72501779 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001010940 exon5 c.G475T p.D159Y TCAGAAGATTATG . 42 4 97 0 . . LMLN 89782 hgsc.bcm.edu;broad.mit.edu;bcgsc.ca 37 3 197703534 197703534 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001136049 exon5 c.G497T p.C166F GGGAGTGTGCCGC . 50 4 97 0 . . HFM1 164045 hgsc.bcm.edu 37 1 91784927 91784927 + Missense_Mutation SNP C C A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 HFM1,NS,carcinoma,0,1 HFM1 NM_001017975 exon24 c.G2603T p.G868V ATGCATCCTAGTT . 69 3 133 0 . 0 LAMA2 3908 hgsc.bcm.edu 37 6 129777488 129777488 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_000426 exon48 c.G6716T p.R2239I CTGGGAGAAATGG . 45 4 74 0 . . FLG 2312 hgsc.bcm.edu;bcgsc.ca 37 1 152281163 152281163 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 FLG,NS,carcinoma,0,1 FLG NM_002016 exon3 c.C6199T p.P2067S GATGGGGCCCAGC . 67 4 121 0 . 0 AP2A1 160 hgsc.bcm.edu 37 19 50303257 50303257 + Silent SNP C C T rs201906388 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 AP2A1,colon,carcinoma,0,1 AP2A1 NM_130787 exon11 c.C1305T p.Y435Y GAAGTACGCCGTG . 41 2 62 0 0.002 0 NEURL4 84461 hgsc.bcm.edu;broad.mit.edu 37 17 7232439 7232439 + Nonsense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001005408 exon1 c.C193T p.Q65X CCGGCTGCTGCCG . 10 5 25 0 . . DLG5 9231 hgsc.bcm.edu 37 10 79613209 79613209 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 DLG5,NS,carcinoma,0,1 DLG5 NM_004747 exon5 c.G767A p.R256Q CGCTCCCGCAGCA . 28 2 60 0 . 0 JAK3 3718 hgsc.bcm.edu 37 19 17951082 17951082 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 JAK3_ENST00000458235,colon,carcinoma,0,2 JAK3_ENST00000458235 NM_000215 exon9 c.G1211A p.S404N TGGGGGCTGCGGC . 24 2 28 0 . 0 SP4 6671 hgsc.bcm.edu;broad.mit.edu;ucsc.edu 37 7 21468306 21468306 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 SP4,colon,carcinoma,0,1 SP4 NM_003112 exon2 c.G19A p.E7K AAGAAGGAGGAGG . 39 5 67 1 . 0 FRG1 2483 hgsc.bcm.edu 37 4 190884267 190884267 + Missense_Mutation SNP G G A rs373037319 TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 FRG1,middle_lobe,carcinoma,0,1 FRG1 NM_004477 exon9 c.G760A p.D254N AAAGCCGACAGAT . 34 3 77 1 . 0 KRAS 3845 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 12 25398285 25398285 + Missense_Mutation SNP C C G rs121913530 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 KRAS_ENST00000256078,NS,adenocarcinoma,+1,6023 KRAS_ENST00000256078 NM_004985 exon2 c.G34C p.G12R CGCCACCAGCTCC . 45 9 56 0 . +1 ITGA6 3655 hgsc.bcm.edu 37 2 173349546 173349546 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ITGA6_ENST00000409080,NS,carcinoma,0,2 ITGA6_ENST00000409080 NM_000210 exon12 c.G1586T p.R529I AAAGAAGAAAATC . 39 2 102 0 . 0 RPL10A 4736 hgsc.bcm.edu 37 6 35438392 35438392 + Missense_Mutation SNP G G T rs1061530 alternate_allele TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 RPL10A,colon,carcinoma,0,1 RPL10A NM_007104 exon6 c.G519T p.K173N CGTGAAGATGACA . 53 2 122 0 . 0 FAM118B 79607 hgsc.bcm.edu;bcgsc.ca 37 11 126131328 126131328 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_024556 exon8 c.G991T p.V331L GGGATGGTGAGAG . 69 4 81 0 . . CKS1B 1163 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 1 154950570 154950570 + Missense_Mutation SNP A A T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001826 exon2 c.A167T p.H56L GGGTCCATTATAT . 73 15 148 0 . . TNFRSF21 27242 hgsc.bcm.edu 37 6 47251781 47251781 + Missense_Mutation SNP T T C novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 T T . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 TNFRSF21,right_lower_lobe,carcinoma,0,1 TNFRSF21 NM_014452 exon3 c.A1136G p.K379R GGCCCCTTTTTCA . 29 2 55 0 . 0 A1CF 29974 hgsc.bcm.edu;broad.mit.edu;ucsc.edu;bcgsc.ca 37 10 52601740 52601740 + Missense_Mutation SNP A A G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . NM_001198820 exon6 c.T271C p.Y91H TTTCATAAATTTT . 41 17 88 0 . . MIER1 57708 hgsc.bcm.edu 37 1 67411833 67411833 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G . . . . Unknown Untested Somatic . WXS none . . Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 MIER1_ENST00000401041,bladder,carcinoma,0,2 MIER1_ENST00000401041 NM_001077700 exon4 c.G194T p.G65V TACCAGGAGGTTC . 62 3 133 0 . 0 PLK3 1263 broad.mit.edu 37 1 45266806 45266806 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . PLK3 NM_004073 exon3 c.G417T p.L139F TTTCTTGGAGCTC . 25 3 48 0 . 41 WDFY4 57705 broad.mit.edu 37 10 49982677 49982677 + Nonsense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . WDFY4 NM_020945 exon14 c.G2728T p.E910X ATCTTTGAGAAGC . 27 9 47 0 . 205 PTPN21 11099 broad.mit.edu;bcgsc.ca 37 14 88946343 88946343 + Missense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . PTPN21 NM_007039 exon13 c.G1432A p.G478S AGCTGCCGATGTT . 13 4 21 0 . 113 CHD2 1106 broad.mit.edu 37 15 93552420 93552420 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . CHD2 NM_001271 exon35 c.G4459T p.D1487Y CAGCTCGACAAAC . 37 3 62 0 . 280 . 0 broad.mit.edu 37 16 32126964 32126964 + RNA DEL T T - novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . CCCCCCTGCCGCC . 6 2 4 0 . . PLIN4 729359 broad.mit.edu 37 19 4510665 4510665 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . PLIN4 NM_001080400 exon3 c.C3265A p.P1089T GCTCCGGGCCTAC . 38 3 76 0 . 191 ZNF837 116412 broad.mit.edu 37 19 58879979 58879979 + Frame_Shift_Del DEL G G - novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . ZNF837 NM_138466 exon3 c.721delC p.Q241fs CCGCCTGCTGCTG . 7 2 8 0 . 16 SULT4A1 25830 broad.mit.edu 37 22 44229568 44229568 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . SULT4A1 NM_014351 exon5 c.C555A p.H185Q CATGCGGTGCTCC . 17 3 40 0 . 26 CPNE9 151835 broad.mit.edu;bcgsc.ca 37 3 9746275 9746275 + Missense_Mutation SNP C C G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . CPNE9 . . . . AGGAACCTGCTAG . 19 8 49 0 . 45 C5orf60 285679 broad.mit.edu 37 5 179069979 179069979 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . C5orf60 NM_001142306 exon4 c.C574A p.L192M AGCTCAGGGATGA . 39 3 71 0 . 24 HSP90AB1 3326 broad.mit.edu 37 6 44221231 44221231 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 HSP90AB1,colon,carcinoma,-1,1 HSP90AB1 NM_007355 exon12 c.G2071T p.D691Y GGTATTGATGAAG . 34 3 38 0 . 83 ACHE 43 broad.mit.edu;ucsc.edu;bcgsc.ca 37 7 100490325 100490325 + Missense_Mutation SNP G G A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . ACHE NM_000665 exon3 c.C1183T p.R395W CGACCCGCACCCC . 116 16 102 1 . 80 GAGE12J 729396 broad.mit.edu 37 X 49179682 49179682 + Nonsense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 Untested Somatic Phase_I WXS none Illumina GAIIx 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . GAGE12J NM_001098406 exon2 c.C10T p.R4X AGTTGGCGAGGAA . 597 8 888 0 . 6 FLNB 2317 ucsc.edu 37 3 58090844 58090844 + Nonsense_Mutation SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . FLNB NM_001457 exon11 c.C1648T p.Q550X GGTATGCAGAAAG . 40 4 70 0 . 430 NAMPT 10135 ucsc.edu;bcgsc.ca 37 7 105894816 105894816 + Silent SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . NAMPT NM_005746 exon9 c.C1224A p.G408G CCCAAGGCCATTA . 36 4 70 0 . 37 STAT6 6778 ucsc.edu;bcgsc.ca 37 12 57498569 57498569 + Missense_Mutation SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . STAT6 NM_001178079 exon10 c.C1029A p.N343K CACAGTGTTGTTG . 12 4 25 0 . 69 ARG2 384 ucsc.edu;bcgsc.ca 37 14 68114848 68114848 + Silent SNP G G T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G G Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . ARG2 NM_001172 exon7 c.G807T p.G269G TGTCGGGGGACTA . 43 4 53 0 . 20 ISLR2 57611 ucsc.edu 37 15 74427081 74427081 + Silent SNP C C T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C C Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . ISLR2 NM_001130138 exon4 c.C1986T p.G662G AGGCGGCGAGGCG . 34 4 88 0 . 78 CYP2A6 1548 ucsc.edu 37 19 41355849 41355849 + Silent SNP A A G rs2302990 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 A A Unknown Untested Somatic WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . CYP2A6 NM_000762 exon2 c.T217C p.L73L GCCCCAAGTGAAT . 52 8 64 5 . 69 SNRNP200 23020 bcgsc.ca 37 2 96962808 96962808 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . SNRNP200 NM_014014 exon12 c.C1378A p.Q460K GCAGTTGCTAGAA . 21 3 34 0 . 195 NMUR1 10316 bcgsc.ca 37 2 232393062 232393062 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . NMUR1 NM_006056 exon2 c.C670A p.P224T CCCGTGGGCGGAC . 12 3 34 0 . 46 COPS7B 64708 bcgsc.ca 37 2 232653436 232653436 + Silent SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . COPS7B NM_022730 exon2 c.G156T p.V52V CAACGTGCAGGAG . 64 4 107 0 . 14 DMXL1 1657 bcgsc.ca 37 5 118580098 118580098 + Missense_Mutation SNP C A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . DMXL1 NM_005509 exon42 c.C8686A p.P2896T TATGCTCCAAAAC . 61 4 92 0 . 268 TMCO6 55374 bcgsc.ca 37 5 140024571 140024571 + Missense_Mutation SNP C T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . TMCO6 NM_018502 exon12 c.C1370T p.A457V CCTAGGCTGTTCA . 13 3 19 0 . 30 XPO5 57510 bcgsc.ca 37 6 43501688 43501688 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . XPO5 NM_020750 exon21 c.C2399A p.T800N GCCTTGGTGAAAG . 22 3 33 0 . 79 SGK1 6446 bcgsc.ca 37 6 134492266 134492266 + Missense_Mutation SNP G T T rs78176488 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 SGK1_ENST00000528577,NS,carcinoma,0,5 SGK1 NM_001143676 exon12 c.C1218A p.N406K AGGCTTGTTCAGA . 37 15 53 1 . 387 TBX20 57057 bcgsc.ca 37 7 35242184 35242184 + Missense_Mutation SNP G A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . TBX20 NM_001077653 exon8 c.C1202T p.A401V GCAATGGCCGATG . 47 4 77 0 . 96 POLM 27434 bcgsc.ca 37 7 44113248 44113248 + Silent SNP G A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . POLM NM_013284 exon10 c.C1374T p.S458S CCCATGGCTGTTC . 33 4 64 0 . 50 . 0 bcgsc.ca 37 9 90038777 90038777 + RNA SNP G A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . ATTACAGCAAACT . 12 3 30 0 . . MUC2 4583 bcgsc.ca 37 11 1093312 1093312 + Missense_Mutation SNP C G G novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . MUC2 NM_002457 exon30 c.C5131G p.P1711A CCAACCCCAACAC . 279 18 487 17 . 614 PHF21A 51317 bcgsc.ca 37 11 45986887 45986887 + Missense_Mutation SNP G T T rs188195248 bycluster TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . PHF21A NM_016621 exon9 c.C975A p.S325R TGGCTTGCTAAGC . 43 13 55 6 G|0.999;T|0.001 107 TRPM1 4308 bcgsc.ca 37 15 31355481 31355481 + Missense_Mutation SNP C T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . TRPM1 NM_001252020 exon7 c.G856A p.V286M GGGGCACGCCCTG . 22 3 27 0 . 183 CTDSPL2 51496 bcgsc.ca 37 15 44807020 44807020 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . CTDSPL2 NM_016396 exon10 c.G1090T p.D364Y ATACTAGACCCTA . 45 4 102 0 . 31 FAM20A 54757 bcgsc.ca 37 17 66538202 66538202 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . FAM20A NM_017565 exon7 c.C1033A p.P345T GGGACGGCAGGAA . 24 3 56 0 . 35 RPTOR 57521 bcgsc.ca 37 17 78811735 78811735 + Missense_Mutation SNP C A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . RPTOR NM_001163034 exon10 c.C1150A p.L384M TGGGACCTGGCTG . 22 3 37 0 . 122 KDM4B 23030 bcgsc.ca 37 19 5041222 5041222 + Missense_Mutation SNP C A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 C - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 KDM4B_ENST00000381759,NS,carcinoma,0,2 KDM4B NM_015015 exon5 c.C392A p.P131Q TCTCCCCGATCTA . 43 4 43 0 . 120 ZNF208 7757 bcgsc.ca 37 19 22154193 22154193 + Missense_Mutation SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 ZNF208_ENST00000428290,NS,carcinoma,+2,3 ZNF208 NM_007153 exon4 c.C3643A p.H1215N TCTTGTGATATCT . 29 3 46 0 . 817 . 6465 bcgsc.ca 37 X 63652534 63652534 + RNA SNP G A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . AGCCAGGAAGGGC . 11 4 23 0 . . . 642812 bcgsc.ca 37 X 115238617 115238617 + RNA SNP G A A novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . . . . . . AAATCTGGATGTT . 68 18 139 0 . . ELF4 2000 bcgsc.ca 37 X 129205393 129205393 + Silent SNP G T T novel TCGA-3X-AAVB-01A-31D-A417-09 TCGA-3X-AAVB-10A-01D-A41A-09 G - - - - - Unknown Untested Somatic Phase_1 WXS none Illumina HiSeq 3b4557a5-53c5-475e-81e1-945411375b6f d7040563-8449-489d-9155-a19f0819a6c7 . ELF4 NM_001421 exon6 c.C534A p.I178I CTTCCGGACTATG . 8 3 19 0 . 67