Hugo_Symbol Entrez_Gene_Id Center NCBI_Build Chromosome Start_Position End_Position Strand Variant_Classification Variant_Type Reference_Allele Tumor_Seq_Allele1 Tumor_Seq_Allele2 dbSNP_RS dbSNP_Val_Status Tumor_Sample_Barcode Matched_Norm_Sample_Barcode Match_Norm_Seq_Allele1 Match_Norm_Seq_Allele2 Tumor_Validation_Allele1 Tumor_Validation_Allele2 Match_Norm_Validation_Allele1 Match_Norm_Validation_Allele2 Verification_Status Validation_Status Mutation_Status Sequencing_Phase Sequence_Source Validation_Method Score BAM_File Sequencer Tumor_Sample_UUID Matched_Norm_Sample_UUID chromosome_name_WU start_WU stop_WU reference_WU variant_WU type_WU gene_name_WU transcript_name_WU transcript_species_WU transcript_source_WU transcript_version_WU strand_WU transcript_status_WU trv_type_WU c_position_WU amino_acid_change_WU ucsc_cons_WU domain_WU all_domains_WU deletion_substructures_WU transcript_error_WU default_gene_name_WU gene_name_source_WU ensembl_gene_id normal_ref_reads normal_var_reads normal_vaf tumor_ref_reads tumors_var_reads tumor_vaf EVS_EA EVS_AA EVS_All APOBR 0 genome.wustl.edu 37 16 28507415 28507417 + In_Frame_Del DEL GGA GGA - TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 GGA GGA Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 16 28507415 28507417 GGA - DEL APOBR ENST00000564831 human ensembl 69_37n +1 known in_frame_del c.1053_1055 p.E353in_frame_del 0.000:0.005:0.010 NULL NULL - no_errors APOBR HGNC ENSG00000184730 17 0 0.00 16 4 18.18 - - - ARHGAP18 0 genome.wustl.edu 37 6 129937374 129937374 + Missense_Mutation SNP G G A TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 6 129937374 129937374 G A SNP ARHGAP18 ENST00000275189 human ensembl 69_37n -1 known missense c.1027 p.P343S 1.000 pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom pfam_RhoGAP_dom,superfamily_Rho_GTPase_activation_prot,smart_RhoGAP_dom,pfscan_RhoGAP_dom - no_errors ARHGAP18 HGNC ENSG00000146376 144 0 0.00 307 74 19.42 - - - CACNA1E 0 genome.wustl.edu 37 1 181726119 181726119 + Missense_Mutation SNP C C T TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 1 181726119 181726119 C T SNP CACNA1E ENST00000367573 human ensembl 69_37n +1 known missense c.4186 p.R1396C 1.000 pfam_Ion_trans_dom pfam_Ion_trans_dom,pfam_VDCC_a1su_IQ,pfam_PKD1_2_channel,pfscan_EF_HAND_2,prints_VDCCAlpha1,prints_VDCC_R_a1su - no_errors CACNA1E HGNC ENSG00000198216 261 0 0.00 510 115 18.40 - - - CIT 0 genome.wustl.edu 37 12 120156088 120156088 + Missense_Mutation SNP G G A TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 12 120156088 120156088 G A SNP CIT ENST00000261833 human ensembl 69_37n -1 known missense c.4004 p.P1335L 1.000 pirsf_Citron_Rho-interacting_kinase pfam_Citron,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_Pkinase_C,superfamily_Kinase-like_dom,superfamily_HR1_rho-bd,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,smart_AGC-kinase_C,smart_Prot_Kinase_C-like_PE/DAG-bd,smart_Pleckstrin_homology,smart_Citron,pirsf_Citron_Rho-interacting_kinase,pfscan_Pleckstrin_homology,pfscan_Prot_Kinase_C-like_PE/DAG-bd,pfscan_Prot_kinase_cat_dom - no_errors CIT HGNC ENSG00000122966 80 0 0.00 127 27 17.53 - - - CTAG2 0 genome.wustl.edu 37 X 153881613 153881613 + Silent SNP G G A TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 X 153881613 153881613 G A SNP CTAG2 ENST00000369585 human ensembl 69_37n -1 known silent c.177 p.G59 0.000 NULL pfam_EKC/KEOPS_Pcc1 - no_errors CTAG2 HGNC ENSG00000126890 11 0 0.00 70 28 28.57 - - - CTGF 0 genome.wustl.edu 37 6 132270681 132270681 + Missense_Mutation SNP C C T TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 6 132270681 132270681 C T SNP CTGF ENST00000367976 human ensembl 69_37n -1 known missense c.773 p.R258H 1.000 pfam_Cys_knot,pirsf_IGFBP_CNN,pfscan_Cys_knot_C pfam_Cys_knot,pfam_IGFBP-like,pfam_VWF_C,pfam_Thrombospondin_1_rpt,superfamily_Thrombospondin_1_rpt,smart_IGFBP-like,smart_VWF_C,smart_Thrombospondin_1_rpt,smart_Cys_knot_C,pirsf_IGFBP_CNN,pfscan_Cys_knot_C,pfscan_Thrombospondin_1_rpt,pfscan_VWF_C - no_errors CTGF HGNC ENSG00000118523 110 0 0.00 187 41 17.98 - - - DDC 0 genome.wustl.edu 37 7 50605566 50605566 + Missense_Mutation SNP C C T TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 7 50605566 50605566 C T SNP DDC ENST00000357936 human ensembl 69_37n -1 known missense c.427 p.V143M 1.000 pfam_PyrdxlP-dep_de-COase,pfam_ArAA_b-elim_lyase/Thr_aldolase,superfamily_PyrdxlP-dep_Trfase_major_dom,prints_Aromatic_deC pfam_PyrdxlP-dep_de-COase,pfam_ArAA_b-elim_lyase/Thr_aldolase,superfamily_PyrdxlP-dep_Trfase_major_dom,prints_Aromatic_deC - no_errors DDC HGNC ENSG00000132437 223 0 0.00 402 93 18.75 - - - HIPK2 0 genome.wustl.edu 37 7 139257730 139257730 + Silent SNP G G C TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 7 139257730 139257730 G C SNP HIPK2 ENST00000406875 human ensembl 69_37n -1 known silent c.3540 p.T1180 1.000 NULL pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,pfam_LipoPS_kinase,superfamily_Kinase-like_dom,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Prot_kinase_cat_dom - no_errors HIPK2 HGNC ENSG00000064393 152 0 0.00 199 58 22.57 - - - NARS2 0 genome.wustl.edu 37 11 78204212 78204212 + Missense_Mutation SNP G G C TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 11 78204212 78204212 G C SNP NARS2 ENST00000281038 human ensembl 69_37n -1 known missense c.719 p.P240R 1.000 pfam_aa-tRNA-synt_II,pfscan_aa-tRNA-synth_II,prints_Asp/Asn-tRNA-synth_IIb,tigrfam_Asn-tRNA-synth_IIb pfam_aa-tRNA-synt_II,pfam_NA-bd_OB_tRNA-helicase,superfamily_NA-bd_OB-fold-like,pfscan_aa-tRNA-synth_II,prints_Asp/Asn-tRNA-synth_IIb,tigrfam_Asn-tRNA-synth_IIb - no_errors NARS2 HGNC ENSG00000137513 43 0 0.00 189 31 13.96 - - - OR4N4 0 genome.wustl.edu 37 15 22382595 22382595 + Silent SNP A A G TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 15 22382595 22382595 A G SNP OR4N4 ENST00000328795 human ensembl 69_37n +1 known silent c.123 p.G41 0.998 pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_7TM_GPCR_Rhodpsn pfam_7TM_GPCR_Rhodpsn,pfscan_GPCR_Rhodpsn_supfam,prints_Olfact_rcpt,prints_7TM_GPCR_Rhodpsn - no_errors OR4N4 HGNC ENSG00000183706 478 0 0.00 1096 134 10.89 - - - PIK3CA 0 genome.wustl.edu 37 3 178936095 178936095 + Missense_Mutation SNP A A G TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 A A Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 3 178936095 178936095 A G SNP PIK3CA ENST00000263967 human ensembl 69_37n +1 known missense c.1637 p.Q546R 1.000 pfam_PInositide-3_kin_accessory_dom,superfamily_ARM-type_fold,smart_PInositide-3_kin_accessory_dom pfam_PInositide-3_kin_accessory_dom,pfam_PI3/4_kinase_cat_dom,pfam_PI3K_Ras-bd_dom,pfam_PI3K_C2_dom,pfam_PI3K_adapt-bd_dom,superfamily_Kinase-like_dom,superfamily_ARM-type_fold,superfamily_C2_Ca/lipid-bd_dom_CaLB,smart_PI3K_adapt-bd_dom,smart_PI3K_Ras-bd_dom,smart_PI3K_C2_dom,smart_PInositide-3_kin_accessory_dom,smart_PI3/4_kinase_cat_dom,pfscan_PI3/4_kinase_cat_dom - no_errors PIK3CA HGNC ENSG00000121879 63 0 0.00 140 42 23.08 - - - RAD21 0 genome.wustl.edu 37 8 117862955 117862955 + Missense_Mutation SNP C C G TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 C C Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 8 117862955 117862955 C G SNP RAD21 ENST00000297338 human ensembl 69_37n -1 known missense c.1522 p.E508Q 1.000 NULL pfam_Rad21_Rec8_N,pfam_Rad21/Rec8_C_eu,pfam_ScpA - no_errors RAD21 HGNC ENSG00000164754 228 0 0.00 487 126 20.55 - - - TTN 0 genome.wustl.edu 37 2 179467306 179467306 + Missense_Mutation SNP G G T TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 G G Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 2 179467306 179467306 G T SNP TTN ENST00000342992 human ensembl 69_37n -1 known missense c.47119 p.P15707T 0.922 pfam_Fibronectin_type3,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Fibronectin_type3,pfscan_Fibronectin_type3 pfam_Ig_I-set,pfam_Fibronectin_type3,pfam_Immunoglobulin,pfam_Ig_V-set,pfam_Titin_Z,pfam_PPAK_motif,pfam_Prot_kinase_cat_dom,pfam_Ser-Thr/Tyr_kinase_cat_dom,superfamily_Kinase-like_dom,superfamily_Fibronectin_type3,superfamily_Calpain_domain_III,superfamily_RNaseH-like_dom,smart_Ig_sub,smart_Ig_sub2,smart_Ig_V-set_subgr,smart_Fibronectin_type3,smart_Ser/Thr_dual-sp_kinase_dom,smart_Tyr_kinase_cat_dom,pfscan_Fibronectin_type3,pfscan_Prot_kinase_cat_dom,pfscan_Ig-like - no_errors TTN HGNC ENSG00000155657 78 0 0.00 180 55 23.40 - - - ZNF45 0 genome.wustl.edu 37 19 44418767 44418767 + Missense_Mutation SNP T T C TCGA-A2-A0EW-01A-21D-A10Y-09 TCGA-A2-A0EW-10A-01D-A110-09 T T Unknown Untested Somatic Phase_IV WXS none 1 dbGAP Illumina GAIIx a045a04e-4f7b-4f9a-a733-47ad24475496 7ada2974-e227-405b-82c2-53909e722858 19 44418767 44418767 T C SNP ZNF45 ENST00000269973 human ensembl 69_37n -1 known missense c.821 p.K274R 1.000 pfscan_Znf_C2H2 pfam_Znf_C2H2,pfam_Krueppel-associated_box,superfamily_Krueppel-associated_box,smart_Krueppel-associated_box,smart_Znf_C2H2-like,pfscan_Znf_C2H2,pfscan_Krueppel-associated_box - no_errors ZNF45 HGNC ENSG00000124459 127 0 0.00 222 56 20.14 - - -